Detailed information for compound 511366

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 332.394 | Formula: C18H24N2O4
  • H donors: 1 H acceptors: 3 LogP: 5.28 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCc1ccc(c(c1)O)Oc1nc(OC)cc(n1)OC
  • InChi: 1S/C18H24N2O4/c1-4-5-6-7-8-13-9-10-15(14(21)11-13)24-18-19-16(22-2)12-17(20-18)23-3/h9-12,21H,4-8H2,1-3H3
  • InChiKey: YNAUOGCPBHCMDN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Chlamydia trachomatis enoyl-acyl-carrier protein reductase Get druggable targets OG5_130466 All targets in OG5_130466
Plasmodium yoelii enoyl-acyl carrier reductase Get druggable targets OG5_130466 All targets in OG5_130466
Plasmodium vivax enoyl-acyl carrier protein reductase Get druggable targets OG5_130466 All targets in OG5_130466
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase Get druggable targets OG5_130466 All targets in OG5_130466
Plasmodium knowlesi enoyl-acyl carrier reductase, putative Get druggable targets OG5_130466 All targets in OG5_130466
Plasmodium berghei enoyl-acyl carrier reductase Get druggable targets OG5_130466 All targets in OG5_130466
Trichomonas vaginalis hypothetical protein Get druggable targets OG5_130466 All targets in OG5_130466
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) Get druggable targets OG5_130466 All targets in OG5_130466
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) Get druggable targets OG5_130466 All targets in OG5_130466
Neospora caninum enoyl-acyl carrier reductase, putative Get druggable targets OG5_130466 All targets in OG5_130466
Toxoplasma gondii enoyl-acyl carrier reductase ENR Get druggable targets OG5_130466 All targets in OG5_130466
Plasmodium falciparum enoyl-acyl carrier reductase Get druggable targets OG5_130466 All targets in OG5_130466
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase Get druggable targets OG5_130466 All targets in OG5_130466
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0048 0.0085
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0075 0.0596 0.0774
Loa Loa (eye worm) hypothetical protein 0.0454 0.4377 0.7779
Loa Loa (eye worm) hypothetical protein 0.0068 0.0532 0.0946
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0256 0.2403 0.3931
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.022 0.0239
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0596 0.0774
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.2577 0.8776
Echinococcus granulosus chromobox protein 1 0.0074 0.0585 0.0585
Loa Loa (eye worm) TK/EGFR protein kinase 0.0159 0.1435 0.2551
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0037 0.022 0.022
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0387 0.123
Echinococcus granulosus g protein coupled receptor 0.0141 0.1253 0.1253
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0387 0.0503
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.022 0.0239
Echinococcus granulosus glutamate receptor 2 0.0196 0.1803 0.1803
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0282 0.2663 0.5659
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0115 0.0245
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.022 0.022
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0016 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0062 0.0102
Schistosoma mansoni jumonji domain containing protein 0.008 0.065 0.0706
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0141 0.1253 0.1253
Echinococcus multilocularis g protein coupled receptor 0.0141 0.1253 0.1253
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0283 0.0307
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0148 0.1325 0.1325
Schistosoma mansoni hypothetical protein 0.0017 0.0016 0.0017
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0239 0.0814
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0152 0.0271
Treponema pallidum NADH oxidase 0.0282 0.2663 0.9055
Trypanosoma cruzi calmodulin 0.0026 0.0108 0.014
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0032 0.0172 0.0306
Echinococcus multilocularis receptor type guanylyl cyclase 0.003 0.0146 0.0146
Echinococcus multilocularis hyperpolarization activated cyclic 0.0042 0.0271 0.0271
Echinococcus granulosus nmda type glutamate receptor 0.0197 0.182 0.182
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0075 0.0596 0.1586
Loa Loa (eye worm) hypothetical protein 0.0081 0.0659 0.117
Schistosoma mansoni neuropeptide f receptor 76f 0.0141 0.1253 0.1361
Echinococcus granulosus neuropeptide s receptor 0.0628 0.6112 0.6112
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0136 0.1209 0.1209
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0016 0.0016
Brugia malayi CXXC zinc finger family protein 0.003 0.0152 0.0249
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0183 0.1678 0.1678
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0141 0.1253 0.1361
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0075 0.0596 0.2026
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0096 0.0204
Loa Loa (eye worm) hypothetical protein 0.0579 0.5626 1
Echinococcus granulosus epidermal growth factor receptor 0.0159 0.1435 0.1435
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Brugia malayi protein-tyrosine kinase 0.0037 0.0217 0.0355
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0283 0.06
Echinococcus granulosus lamin 0.0029 0.0134 0.0134
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.003 0.0146 0.0607
Schistosoma mansoni biogenic amine receptor 0.0141 0.1253 0.1361
Plasmodium vivax SET domain protein, putative 0.0032 0.0171 0.0363
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0209 0.0342
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0006 0.0017
Echinococcus multilocularis geminin 0.0179 0.1639 0.1639
Loa Loa (eye worm) neuropeptide F receptor 0.0141 0.1253 0.2227
Plasmodium vivax amine transporter, putative 0.0043 0.0283 0.06
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0062 0.0062
Schistosoma mansoni glutamate receptor AMPA 0.0172 0.1561 0.1696
Schistosoma mansoni cpg binding protein 0.003 0.0152 0.0165
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0037 0.022 0.036
Entamoeba histolytica hypothetical protein 0.0025 0.0096 0.0327
Treponema pallidum thioredoxin reductase (trxB) 0.0075 0.0596 0.1898
Schistosoma mansoni amine GPCR 0.0141 0.1253 0.1361
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.022 0.022
Echinococcus multilocularis insulin receptor 0.0052 0.0364 0.0364
Schistosoma mansoni glutamate receptor kainate 0.0172 0.1561 0.1696
Onchocerca volvulus 0.0141 0.1253 0.5214
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0151 0.1357 0.5096
Giardia lamblia Fructose-bisphosphate aldolase 0.0309 0.2936 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0398 0.3826 0.3826
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0037 0.022 0.0239
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0146 0.0259
Trypanosoma brucei trypanothione reductase 0.0487 0.4707 0.6112
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0727 0.079
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0273 0.2577 0.4216
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0016 0.0034
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0062 0.0068
Onchocerca volvulus 0.0043 0.0283 0.1176
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0096 0.036
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0096 0.0812 0.1054
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0221 0.2054 0.3651
Echinococcus granulosus microtubule associated protein 2 0.073 0.7138 0.7138
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0141 0.1253 0.205
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0015 0.0002 0.0004
Loa Loa (eye worm) norepinephrine transporter 0.0256 0.2403 0.4271
Echinococcus multilocularis RUN 0.0042 0.0265 0.0265
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0141 0.1253 0.2227
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0062 0.0102
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0376 0.0614
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.022 0.022
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0387 0.0503
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0141 0.1253 0.1253
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0198 0.0528
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0133 0.0448
Schistosoma mansoni myosin xvIII 0.0141 0.1253 0.1361
Brugia malayi follicle stimulating hormone receptor 0.0141 0.1253 0.205
Loa Loa (eye worm) hypothetical protein 0.0088 0.0727 0.1292
Echinococcus multilocularis shaker cognate 0.0037 0.022 0.022
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0021 0.0054 0.0201
Onchocerca volvulus 0.0042 0.0265 0.1105
Brugia malayi Transient-receptor-potential like protein 0.0037 0.022 0.036
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0283 0.06
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Echinococcus granulosus cpg binding protein 0.0032 0.017 0.017
Echinococcus multilocularis jun protein 0.0089 0.0736 0.0736
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0037 0.022 0.022
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0136 0.1209 0.1314
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0062 0.0111
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0601 0.5851 0.7598
Brugia malayi calmodulin 0.0026 0.0108 0.0176
Onchocerca volvulus 0.0141 0.1253 0.5214
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0073 0.0582 0.0582
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0024 0.0091 0.0161
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0211 0.0449
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0032 0.0167 0.0354
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0141 0.1253 0.1253
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0037 0.022 0.036
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0049 0.0334 0.1135
Plasmodium falciparum thioredoxin reductase 0.0487 0.4707 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0141 0.1253 0.1253
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0196 0.1803 0.1803
Echinococcus multilocularis calmodulin 0.0026 0.0108 0.0108
Schistosoma mansoni ABC transporter 0.0016 0.0005 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0105 0.0353
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0141 0.1253 0.1253
Schistosoma mansoni loxhd1 0.0042 0.0265 0.0288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0157 0.0531
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0229 0.213 0.8863
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0075 0.0596 0.1266
Schistosoma mansoni inositol monophosphatase 0.0039 0.0239 0.026
Echinococcus granulosus voltage dependent calcium channel 0.0056 0.0407 0.0407
Echinococcus multilocularis serotonin receptor 0.0398 0.3826 0.3826
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0041 0.0253 0.0712
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0227 0.0295
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0062 0.0102
Echinococcus granulosus metabotropic glutamate receptor 2 0.0024 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Toxoplasma gondii hypothetical protein 0.0043 0.0283 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0008 0.0023
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0256 0.0256
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0037 0.004
Onchocerca volvulus 0.0141 0.1253 0.5214
Echinococcus granulosus rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Echinococcus multilocularis glutamate receptor 2 0.0122 0.107 0.107
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.026 0.026
Schistosoma mansoni sodium/chloride dependent transporter 0.0043 0.0283 0.0307
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Giardia lamblia Calmodulin 0.0026 0.0108 0.0268
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0141 0.1253 0.1361
Echinococcus multilocularis orexin receptor type 2 0.0141 0.1253 0.1253
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0141 0.1253 0.5214
Brugia malayi Guanylyl cyclase protein 23 0.003 0.0146 0.0239
Loa Loa (eye worm) neuropeptide F receptor 0.0141 0.1253 0.2227
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0239 0.0239
Schistosoma mansoni tyrosine kinase 0.0086 0.0707 0.0768
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0075 0.0596 0.0596
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0282 0.2663 1
Leishmania major NADH dehydrogenase, putative 0.0075 0.0596 0.0774
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0048 0.0048
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0024 0.0091 0.0161
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0787 0.77 1
Onchocerca volvulus 0.0141 0.1253 0.5214
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0141 0.1253 0.1253
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0153 0.0153
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0052 0.0364 0.0364
Schistosoma mansoni intermediate filament proteins 0.0029 0.0134 0.0145
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0141 0.1253 0.205
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0161
Schistosoma mansoni sodium-dependent amino acid transporter 0.0043 0.0283 0.0307
Loa Loa (eye worm) hypothetical protein 0.0075 0.0596 0.1059
Loa Loa (eye worm) TK protein kinase 0.0037 0.0217 0.0385
Loa Loa (eye worm) voltage-dependent calcium channel 0.0056 0.0407 0.0723
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0227 0.0295
Schistosoma mansoni chromobox protein 0.0074 0.0585 0.0635
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0196 0.1803 0.1803
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0324 0.0529
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0282 0.2663 0.3459
Toxoplasma gondii calmodulin, putative 0.0026 0.0108 0.0229
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0141 0.1253 0.1253
Schistosoma mansoni amine GPCR 0.0141 0.1253 0.1361
Echinococcus multilocularis neuropeptides capa receptor 0.0141 0.1253 0.1253
Schistosoma mansoni glutamate receptor NMDA 0.0347 0.3311 0.3597
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0141 0.1253 0.1361
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0283 0.0307
Onchocerca volvulus 0.0141 0.1253 0.5214
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0042 0.0271 0.0271
Onchocerca volvulus Glucosylceramidase homolog 0.0179 0.1639 0.682
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0265 0.0265
Loa Loa (eye worm) hypothetical protein 0.0256 0.2403 0.4271
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0387 0.1315
Schistosoma mansoni hypothetical protein 0.0017 0.0016 0.0017
Brugia malayi Bromodomain containing protein 0.0031 0.0157 0.0257
Echinococcus granulosus orexin receptor type 2 0.0141 0.1253 0.1253
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1639 0.558
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0062 0.0062
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0287 0.0312
Echinococcus multilocularis potassium voltage gated channel protein 0.0037 0.022 0.022
Echinococcus multilocularis voltage dependent calcium channel 0.0136 0.1209 0.1209
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0062 0.0068
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.2936 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0283 0.0462
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0041 0.0253 0.0538
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0036 0.0211 0.0211
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0222 0.0222
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0048 0.0062
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.022 0.0239
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0075 0.0596 0.0596
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0223 0.2079 0.5535
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0024 0.0091 0.0161
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0075 0.0596 0.0975
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0075 0.0596 0.0774
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0016 0.0021
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0062 0.0068
Brugia malayi Probable DNA topoisomerase II 0.0148 0.1325 0.2168
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0261 0.1088
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0062 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0105 0.0353
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0283 0.0307
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0265 0.0265
Schistosoma mansoni coup transcription factor 0.0021 0.0062 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0324 0.1098
Chlamydia trachomatis DNA gyrase subunit A 0.0032 0.0167 0.0625
Brugia malayi hypothetical protein 0.0141 0.1253 0.205
Echinococcus granulosus tyrosine protein kinase Src64B 0.0041 0.0256 0.0256
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0271 0.0295
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0265 0.0564
Echinococcus multilocularis g protein coupled receptor 0.0141 0.1253 0.1253
Brugia malayi G-protein coupled receptor 0.0141 0.1253 0.205
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0062 0.0062
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0256 0.0256
Onchocerca volvulus 0.0075 0.0596 0.248
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0435 0.0925
Loa Loa (eye worm) TK/INSR protein kinase 0.0052 0.0364 0.0646
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0157 0.0333
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0282 0.2663 0.2663
Schistosoma mansoni voltage-gated potassium channel 0.0077 0.062 0.0673
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0037 0.0217 0.0217
Echinococcus multilocularis cpg binding protein 0.0032 0.017 0.017
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0096 0.0812 0.1054
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0171 0.0186
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0075 0.0596 0.2238
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0054 0.0095
Echinococcus multilocularis g protein coupled receptor 0.0141 0.1253 0.1253
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Brugia malayi hypothetical protein 0.0017 0.0021 0.0034
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.0271 0.092
Plasmodium falciparum DNA topoisomerase 2 0.0148 0.1325 0.2816
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0387 0.0503
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1735 0.5908
Chlamydia trachomatis DNA gyrase subunit A 0.0032 0.0167 0.0625
Loa Loa (eye worm) glutamate receptor 2 0.0172 0.1561 0.2775
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0184 0.1689 0.3589
Brugia malayi isocitrate dehydrogenase 0.0017 0.0016 0.0026
Schistosoma mansoni neuropeptide receptor 0.0141 0.1253 0.1361
Schistosoma mansoni amine GPCR 0.0667 0.6501 0.7063
Loa Loa (eye worm) voltage-gated calcium channel 0.0037 0.022 0.0391
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Echinococcus granulosus neuropeptide FF receptor 2 0.0141 0.1253 0.1253
Giardia lamblia DNA topoisomerase II 0.014 0.1248 0.4193
Echinococcus multilocularis microtubule associated protein 2 0.073 0.7138 0.7138
Echinococcus multilocularis neuropeptide s receptor 0.0628 0.6112 0.6112
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0585 0.1989
Schistosoma mansoni lipoxygenase 0.0183 0.1678 0.1823
Trypanosoma brucei cytochrome P450, putative 0.0021 0.0054 0.007
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0546 0.0709
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0075 0.0596 0.1266
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0196 0.1803 0.1803
Schistosoma mansoni opsin-like receptor 0.0141 0.1253 0.1361
Echinococcus granulosus potassium large conductance calcium activated 0.0037 0.022 0.022
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0376 0.0667
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0136 0.1209 0.1314
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0387 0.1315
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0075 0.0596 0.0596
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0141 0.1253 0.1253
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0282 0.2663 0.5659
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.0659 0.1399
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0324 0.042
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1639 0.558
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0282 0.2663 1
Brugia malayi Pre-SET motif family protein 0.0032 0.0171 0.028
Echinococcus granulosus peptide allatostatin:somatostatin 0.0141 0.1253 0.1253
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0036 0.0211 0.0211
Loa Loa (eye worm) inositol-1 0.0039 0.0239 0.0425
Schistosoma mansoni ryanodine receptor related 0.0037 0.022 0.0239
Loa Loa (eye worm) heterochromatin protein 1 0.0074 0.0585 0.104
Onchocerca volvulus 0.003 0.0146 0.0607
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0141 0.0476
Echinococcus multilocularis calcium activated potassium channel 0.0038 0.0225 0.0225
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0075 0.0596 0.0596
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0387 0.0387
Echinococcus multilocularis short transient receptor potential channel 6 0.0037 0.0222 0.0222
Echinococcus multilocularis sodium and chloride dependent glycine 0.0043 0.0283 0.0283
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0062 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0324 0.1098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0008 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0126
Leishmania major cytochrome p450-like protein 0.0021 0.0054 0.007
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0256 0.0256
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0041 0.0253 0.0712
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0392 0.3757 0.7982
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0037 0.022 0.0239
Echinococcus granulosus sodium leak channel non selective protein 0.0037 0.022 0.022
Echinococcus granulosus sodium and chloride dependent glycine 0.0043 0.0283 0.0283
Mycobacterium ulcerans DNA gyrase subunit A 0.0032 0.0167 0.0625
Trypanosoma brucei calmodulin 0.0026 0.0108 0.014
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0037 0.022 0.0239
Schistosoma mansoni hypothetical protein 0.0075 0.0596 0.0647
Leishmania major extracellular receptor, putative 0.0024 0.0091 0.0118
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0283 0.0307
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0937 0.9205 0.9205
Echinococcus granulosus fmrfamide receptor 0.0141 0.1253 0.1253
Echinococcus granulosus serotonin receptor 0.0141 0.1253 0.1253
Schistosoma mansoni glutamate receptor kainate 0.0172 0.1561 0.1696
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0075 0.0596 0.2026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0227 0.0768
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0141 0.1253 0.205
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Mycobacterium ulcerans DNA gyrase subunit B 0.0086 0.071 0.2666
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0136 0.1209 0.1209
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0041 0.0256 0.0256
Echinococcus multilocularis neuropeptide receptor A26 0.0628 0.6112 0.6112
Schistosoma mansoni voltage-dependent calcium channel 0.0037 0.022 0.0239
Schistosoma mansoni tyrosine kinase 0.0084 0.0686 0.0746
Mycobacterium ulcerans dehydrogenase 0.0075 0.0596 0.2238
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0008 0.0011
Mycobacterium tuberculosis Probable dehydrogenase 0.0184 0.1689 0.3589
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0086 0.0712 0.1513
Echinococcus multilocularis serotonin transporter 0.0256 0.2403 0.2403
Echinococcus multilocularis ATP binding cassette sub family G 0.0018 0.0033 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0008 0.0023
Loa Loa (eye worm) hepatopoietin HPO2 0.0036 0.0211 0.0376
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0032 0.0167 0.0625
Trichomonas vaginalis glutamate synthase, putative 0.0075 0.0596 0.2026
Toxoplasma gondii NADPH-glutathione reductase 0.0282 0.2663 0.5659
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0036 0.0209 0.0272
Echinococcus multilocularis lamin 0.0029 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0141 0.1253 0.1361
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0074 0.0584 0.0584
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0239 0.031
Brugia malayi Glutamate receptor 1 precursor 0.0172 0.1561 0.2554
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0184 0.1689 0.3589
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0037 0.022 0.022
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0239 0.031
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0596 0.0774
Schistosoma mansoni neuropeptide receptor 0.0141 0.1253 0.1361
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0016 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1639 0.558
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0016 0.0016
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0141 0.1253 0.1253
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.022 0.022
Trypanosoma brucei calmodulin 0.0026 0.0108 0.014
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0324 0.1098
Brugia malayi MAP kinase sur-1 0.0054 0.0387 0.0633
Echinococcus granulosus g-protein coupled receptor 0.0141 0.1253 0.1253
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0283 0.06
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0037 0.022 0.036
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0166 0.1506 0.1956
Echinococcus multilocularis calmodulin 0.0026 0.0108 0.0108
Loa Loa (eye worm) programmed cell death 8 0.0075 0.0596 0.1059
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0075 0.0596 0.0596
Onchocerca volvulus 0.0141 0.1253 0.5214
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0049 0.0334 0.1135
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0546 0.0709
Schistosoma mansoni glutamate synthase 0.0075 0.0596 0.0647
Echinococcus multilocularis fmrfamide receptor 0.0141 0.1253 0.1253
Schistosoma mansoni amine GPCR 0.0141 0.1253 0.1361
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0062 0.0102
Loa Loa (eye worm) hypothetical protein 0.006 0.0449 0.0799
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0256 0.0256
Loa Loa (eye worm) TYRA-2 protein 0.0141 0.1253 0.2227
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0121 0.1061 0.3985
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0092
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0239 0.026
Echinococcus multilocularis musashi 0.0029 0.0134 0.0134
Brugia malayi Receptor family ligand binding region containing protein 0.0024 0.0091 0.0148
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.022 0.022
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0141 0.1253 0.2227
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0081 0.0659 0.1077
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0042 0.0271 0.0271
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0309 0.2936 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0075 0.0596 0.2026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.2936 1
Leishmania major hypothetical protein, conserved 0.0037 0.022 0.0285
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0043 0.0283 0.1061
Echinococcus multilocularis chromobox protein 1 0.0074 0.0585 0.0585
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0046 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Schistosoma mansoni adenoreceptor 0.0141 0.1253 0.1361
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0601 0.5851 0.7598
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0324 0.0324
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0115 0.0245
Leishmania major hypothetical protein, conserved 0.0036 0.0211 0.0274
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0075 0.0596 0.2026
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0115 0.015
Schistosoma mansoni hypothetical protein 0.0073 0.0582 0.0632
Giardia lamblia NADH oxidase lateral transfer candidate 0.0282 0.2663 0.9061
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0502
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0157 0.0157
Echinococcus multilocularis adenylate cyclase 9 0.0082 0.0672 0.0672
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0075 0.0596 0.2026
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.1194
Schistosoma mansoni microtubule-associated protein tau 0.073 0.7138 0.7755
Onchocerca volvulus 0.0037 0.022 0.0915
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0141 0.1253 0.1253
Toxoplasma gondii hypothetical protein 0.0037 0.022 0.0467
Schistosoma mansoni transient receptor potential channel 0.0037 0.022 0.0239
Mycobacterium ulcerans hypothetical protein 0.0021 0.0062 0.0232
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0376 0.0614
Echinococcus granulosus voltage gated hydrogen channel 1 0.0037 0.022 0.022
Onchocerca volvulus 0.0082 0.0672 0.2796
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0096 0.0204
Echinococcus granulosus tachykinin peptides receptor 99D 0.0141 0.1253 0.1253
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0037 0.022 0.022
Plasmodium falciparum ferrodoxin reductase-like protein 0.0075 0.0596 0.1266
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0086 0.0712 0.2673
Schistosoma mansoni sulfide quinone reductase 0.0075 0.0596 0.0647
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0141 0.1253 0.1361
Onchocerca volvulus 0.0042 0.0265 0.1105
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.2577 0.8776
Echinococcus multilocularis rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0016 0.0016
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0239 0.0898
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0141 0.1253 0.1361
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0141 0.0476
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0086 0.0712 0.2673
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0062 0.0062
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0146 0.0259
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0075 0.0596 0.1266
Onchocerca volvulus 0.0141 0.1253 0.5214
Schistosoma mansoni tyrosine kinase 0.0041 0.0256 0.0278
Schistosoma mansoni biogenic amine (5HT) receptor 0.0398 0.3826 0.4156
Loa Loa (eye worm) hypothetical protein 0.0046 0.0307 0.0546
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0134 0.0219
Loa Loa (eye worm) hypothetical protein 0.0398 0.3826 0.6799
Schistosoma mansoni jun-related protein 0.0072 0.057 0.0619
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0062 0.0068
Loa Loa (eye worm) hypothetical protein 0.025 0.2347 0.4171
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0157 0.0157
Brugia malayi intermediate filament protein 0.0029 0.0134 0.0219
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0347 0.3311 0.3311
Echinococcus multilocularis voltage gated potassium channel 0.0046 0.0307 0.0307
Echinococcus granulosus glutamate synthase 0.0075 0.0596 0.0596
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0075 0.0596 0.1266
Echinococcus granulosus two pore calcium channel protein 1 0.0037 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Echinococcus granulosus calcium activated potassium channel 0.0038 0.0225 0.0225
Echinococcus granulosus ATP binding cassette sub family G 0.0018 0.0033 0.0033
Chlamydia trachomatis DNA gyrase subunit B 0.0086 0.071 0.2666
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0016 0.0016
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0141 0.1253 0.1253
Trypanosoma cruzi ABC transporter, putative 0.0018 0.0033 0.0043
Onchocerca volvulus 0.0141 0.1253 0.5214
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0089 0.0736 0.0736
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0211 0.0274
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0151 0.1357 0.2883
Schistosoma mansoni hypothetical protein 0.0433 0.4169 0.453
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0161
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Schistosoma mansoni voltage-gated ion channel 0.0037 0.022 0.0239
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0183 0.1679 0.5717
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.2936 1
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0075 0.0596 0.0975
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0062 0.0232
Loa Loa (eye worm) CYP4Cod1 0.0021 0.0054 0.0095
Echinococcus granulosus atrial natriuretic peptide receptor 0.0024 0.0091 0.0091
Onchocerca volvulus 0.0029 0.0134 0.0557
Brugia malayi neuropeptide F receptor 0.0141 0.1253 0.205
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.2936 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0062 0.0068
Echinococcus granulosus TRP transient receptor potential channel 0.0037 0.022 0.022
Plasmodium vivax DNA topoisomerase II, putative 0.0148 0.1325 0.2816
Trypanosoma cruzi extracellular receptor, putative 0.0024 0.0091 0.0118
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0183 0.1679 0.5717
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0042 0.0271 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0062 0.0102
Plasmodium falciparum ABC transporter G family member 2 0.0018 0.0033 0.007
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Schistosoma mansoni sulfide quinone reductase 0.0075 0.0596 0.0647
Brugia malayi ERG2 and Sigma1 receptor like protein 0.039 0.3738 0.6116
Loa Loa (eye worm) ryanodine receptor 0.0037 0.022 0.0391
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Loa Loa (eye worm) hypothetical protein 0.0056 0.0407 0.0723
Loa Loa (eye worm) hypothetical protein 0.0256 0.2403 0.4271
Onchocerca volvulus Dual oxidase homolog 0.0077 0.0616 0.2565
Loa Loa (eye worm) serotonin transporter b 0.0256 0.2403 0.4271
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0075 0.0596 0.1266
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0727 0.0727
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0392 0.3757 0.7982
Loa Loa (eye worm) hypothetical protein 0.0036 0.0209 0.0371
Loa Loa (eye worm) hypothetical protein 0.0042 0.0271 0.0482
Echinococcus multilocularis neuropeptide FF receptor 2 0.0141 0.1253 0.1253
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0502
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0596 0.0774
Brugia malayi jmjC domain containing protein 0.0039 0.0239 0.0391
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0502
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0075 0.0596 0.2238
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0282 0.2663 0.3459
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0105 0.0353
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0062 0.0062
Echinococcus granulosus survival motor neuron protein 1 0.025 0.2347 0.2347
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0184 0.1689 0.4497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0141 0.1253 0.1361
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0239 0.081
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0062 0.0062
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0075 0.0596 0.1266
Brugia malayi Protein kinase domain containing protein 0.0052 0.0364 0.0595
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0454 0.4377 0.7161
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0207 0.1916 0.3135
Echinococcus granulosus dro:myosuppressin receptor 0.0141 0.1253 0.1253
Echinococcus granulosus sodium channel protein 0.0451 0.4346 0.4346
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0037 0.022 0.022
Echinococcus granulosus rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0239 0.0508
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0075 0.0596 0.1948
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0283 0.0307
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0048 0.0062
Onchocerca volvulus 0.0141 0.1253 0.5214
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0062 0.0062
Echinococcus granulosus calmodulin 0.0026 0.0108 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0062 0.0111
Echinococcus multilocularis neuropeptides capa receptor 0.0141 0.1253 0.1253
Echinococcus multilocularis somatostatin receptor 0.0141 0.1253 0.1253
Brugia malayi Glutamate receptor 2 precursor 0.0172 0.1561 0.2554
Schistosoma mansoni DNA topoisomerase II 0.0148 0.1325 0.144
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0283 0.0502
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0075 0.0596 0.0774
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0016 0.0026
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0324 0.042
Echinococcus multilocularis g-protein coupled receptor 0.0141 0.1253 0.1253
Echinococcus granulosus intermediate filament protein 0.0029 0.0134 0.0134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0141 0.1253 0.1361
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.2936 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0283 0.0307
Entamoeba histolytica DNA topoisomerase II, putative 0.0148 0.1325 0.4514
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0148 0.1325 0.1325
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0082 0.0672 0.2796
Echinococcus granulosus short transient receptor potential channel 6 0.0037 0.022 0.022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0504 0.0548
Brugia malayi metabotropic glutamate receptor type 2 0.0024 0.0091 0.0148
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0037 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0062 0.0111
Mycobacterium ulcerans hypothetical protein 0.003 0.0146 0.055
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0062 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0062 0.0102
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0126
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0048 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0105 0.0354
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0387 0.0503
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0283 0.0462
Onchocerca volvulus 0.0032 0.0172 0.0717
Onchocerca volvulus 0.007 0.0546 0.227
Entamoeba histolytica calmodulin, putative 0.0026 0.0108 0.0367
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0136 0.1209 0.1978
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0062 0.0102
Plasmodium falciparum thioredoxin reductase 0.0282 0.2663 0.5659
Echinococcus multilocularis transfer RNA-Gly 0.0037 0.022 0.022
Schistosoma mansoni metabotropic glutamate receptor 0.0024 0.0091 0.0099
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0075 0.0596 0.1266
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.022 0.022
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.0271 0.0295
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0133 0.0448
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0024 0.0091 0.0148
Echinococcus granulosus voltage gated potassium channel 0.0046 0.0307 0.0307
Echinococcus granulosus jun protein 0.0089 0.0736 0.0736
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0048 0.0078
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0282 0.2663 1
Echinococcus granulosus tumor protein p63 0.0358 0.3418 0.3418
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0048 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0126
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0282 0.2663 0.2663
Schistosoma mansoni tyrosine kinase 0.0159 0.1435 0.1559
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0075 0.0596 0.2238
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0018 0.0033 0.0043
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0041 0.0256 0.0256
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Schistosoma mansoni transient receptor potential channel 4 0.0037 0.022 0.0239
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.2936 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0141 0.1253 0.1253
Chlamydia trachomatis DNA gyrase subunit B 0.0068 0.0529 0.1987
Schistosoma mansoni voltage-gated potassium channel 0.0077 0.062 0.0673
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0157 0.017
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0037 0.022 0.022
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0075 0.0596 0.0774
Echinococcus granulosus alpha 1A adrenergic receptor 0.0141 0.1253 0.1253
Echinococcus granulosus sex peptide receptor 0.0141 0.1253 0.1253
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0008 0.0011
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0324 0.1102
Leishmania major DNA topoisomerase ii 0.014 0.1246 0.1618
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0105 0.0354
Echinococcus granulosus ATP binding cassette sub family G 0.0018 0.0033 0.0033
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0293 0.0993
Schistosoma mansoni calmodulin 0.0026 0.0108 0.0117
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0223 0.2079 0.7807
Onchocerca volvulus 0.003 0.0152 0.0634
Onchocerca volvulus 0.0141 0.1253 0.5214
Schistosoma mansoni transient receptor potential channel 0.0037 0.0222 0.0242
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0016 0.0021
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0075 0.0596 0.1059
Toxoplasma gondii selenide, water dikinase 0.0075 0.0596 0.1266
Plasmodium vivax ABC transporter G family member 2, putative 0.0018 0.0033 0.007
Echinococcus multilocularis epidermal growth factor receptor 0.0159 0.1435 0.1435
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0037 0.022 0.022
Brugia malayi RE15519p 0.0141 0.1253 0.205
Schistosoma mansoni glutamate receptor NMDA 0.0279 0.2636 0.2864
Loa Loa (eye worm) hypothetical protein 0.0199 0.1837 0.3265
Brugia malayi hypothetical protein 0.0141 0.1253 0.205
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0042 0.0271 0.0482
Leishmania major hypothetical protein, conserved 0.0075 0.0596 0.0774
Loa Loa (eye worm) SRC-1 0.0041 0.0256 0.0454
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0075 0.0596 0.0596
Echinococcus multilocularis ATP binding cassette sub family G 0.0018 0.0033 0.0033
Onchocerca volvulus Neuropeptide F receptor homolog 0.0141 0.1253 0.5214
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0502
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0111
Schistosoma mansoni neuropeptide receptor 0.0141 0.1253 0.1361
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0035 0.0198 0.0745
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0062 0.0062
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0239 0.0898
Schistosoma mansoni glutamate receptor kainate 0.0172 0.1561 0.1696
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0114 0.0986 0.0986
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.111 0.1973
Loa Loa (eye worm) TOPoisomerase family member 0.0148 0.1325 0.2356
Echinococcus granulosus GPCR family 2 0.0017 0.0016 0.0016
Brugia malayi Dopamine receptor protein 1 0.0579 0.5626 0.9205
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0256 0.0256
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0075 0.0596 0.0596
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0282 0.2663 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0134 0.0238
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0454 0.4377 0.4755
Entamoeba histolytica thioredoxin reductase, putative 0.0075 0.0596 0.203
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0048 0.0158
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Echinococcus multilocularis nmda type glutamate receptor 0.0197 0.182 0.182
Schistosoma mansoni hypothetical protein 0.0179 0.1639 0.178
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0046 0.006
Echinococcus granulosus thioredoxin glutathione reductase 0.0487 0.4707 0.4707
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0016 0.0028
Brugia malayi GnHR receptor homolog 0.0141 0.1253 0.205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Schistosoma mansoni hypothetical protein 0.0015 0.0002 0.0002
Brugia malayi hypothetical protein 0.0141 0.1253 0.205
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0037 0.022 0.0915
Loa Loa (eye worm) hypothetical protein 0.0398 0.3826 0.6799
Echinococcus multilocularis sodium channel protein 0.0491 0.4751 0.4751
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0196 0.1803 0.1803
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1639 0.558
Plasmodium vivax DNA gyrase subunit A, putative 0.0032 0.0167 0.0354
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0062 0.0068
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0037 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0048 0.0101
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0207 0.1916 0.3135
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0008 0.0008
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0002 0.0003
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0387 0.0387
Schistosoma mansoni amine GPCR 0.0141 0.1253 0.1361
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0239 0.081
Toxoplasma gondii transporter, cation channel family protein 0.0037 0.022 0.0467
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0008 0.0011
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0307 0.0334
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0048 0.0048
Leishmania major mitochondrial DNA topoisomerase II 0.0166 0.1506 0.1956
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0211 0.0274
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0211 0.0274
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0075 0.0596 0.0774
Entamoeba histolytica protein kinase, putative 0.0033 0.0177 0.0603
Onchocerca volvulus 0.0141 0.1253 0.5214
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0064
Onchocerca volvulus 0.0043 0.0283 0.1176
Trypanosoma cruzi DNA topoisomerase II, putative 0.014 0.1246 0.1618
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0075 0.0596 0.2026
Onchocerca volvulus DNA topoisomerase 2 homolog 0.01 0.0847 0.3524
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0036 0.0209 0.0272
Loa Loa (eye worm) ion channel NompC 0.0037 0.022 0.0391
Trypanosoma brucei calmodulin 0.0026 0.0108 0.014
Giardia lamblia PHD finger protein 15 0.0031 0.0157 0.0438
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0141 0.1253 0.205
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0253 0.0253
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0273 0.2577 0.458
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0239 0.0425
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0171 0.0186
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Echinococcus multilocularis glutamate synthase 0.0075 0.0596 0.0596
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0042 0.0271 0.0295
Echinococcus granulosus calmodulin 0.0026 0.0107 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0261 0.0887
Giardia lamblia GTOR 0.0048 0.0324 0.1011
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0161
Echinococcus granulosus geminin 0.0179 0.1639 0.1639
Leishmania major ferric reductase, putative 0.0036 0.0209 0.0272
Trypanosoma cruzi calmodulin, putative 0.0026 0.0108 0.014
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0075 0.0596 0.2238
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0141 0.1253 0.1361
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0041 0.0256 0.0256
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Schistosoma mansoni biogenic amine receptor 0.0141 0.1253 0.1361
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0022 0.007
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Echinococcus granulosus hyperpolarization activated cyclic 0.0042 0.0271 0.0271
Onchocerca volvulus 0.0024 0.0091 0.0377
Onchocerca volvulus 0.0043 0.0283 0.1176
Echinococcus granulosus transient receptor potential gamma protein 0.0037 0.022 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0227 0.0768
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0141 0.1253 0.1361
Echinococcus granulosus calmodulin 0.0026 0.0108 0.0108
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0141 0.1253 0.1361
Echinococcus granulosus RUN 0.0042 0.0265 0.0265
Echinococcus granulosus rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Loa Loa (eye worm) hypothetical protein 0.0027 0.0115 0.0205
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0075 0.0596 0.1266
Schistosoma mansoni glutamate synthase 0.0075 0.0596 0.0647
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0196 0.1803 0.1803
Echinococcus granulosus voltage dependent calcium channel 0.0136 0.1209 0.1209
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0324 0.042
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0037 0.022 0.0467
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0141 0.1253 0.1253
Echinococcus multilocularis GPCR, family 2 0.0017 0.0016 0.0016
Schistosoma mansoni opsin-like receptor 0.0141 0.1253 0.1361
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0037 0.022 0.036
Brugia malayi Furin-like cysteine rich region family protein 0.0159 0.1435 0.2348
Echinococcus multilocularis epidermal growth factor receptor 0.0086 0.0707 0.0707
Trypanosoma cruzi C-8 sterol isomerase, putative 0.039 0.3738 0.4855
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0018 0.0033 0.0124
Brugia malayi voltage-dependent calcium channel 0.0037 0.022 0.036
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0293 0.0993
Loa Loa (eye worm) TK protein kinase 0.0033 0.0177 0.0315
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0387 0.1315
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0075 0.0596 0.1266
Echinococcus granulosus sodium and chloride dependent glycine 0.0043 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0161
Loa Loa (eye worm) hypothetical protein 0.0256 0.2403 0.4271
Echinococcus granulosus tyrosine protein kinase Blk 0.0037 0.0217 0.0217
Echinococcus multilocularis rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Leishmania major C-8 sterol isomerase-like protein 0.039 0.3738 0.4855
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0037 0.022 0.0285
Echinococcus multilocularis tyrosine protein kinase Blk 0.0037 0.0217 0.0217
Trichomonas vaginalis glutamate synthase, putative 0.0075 0.0596 0.2026
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0075 0.0596 0.2238
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0043 0.0283 0.0462
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0141 0.1253 0.1361
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0024 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0101 0.0858 0.0858
Schistosoma mansoni biogenic amine (5HT) receptor 0.0937 0.9205 1
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0239 0.081
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0171 0.0363
Toxoplasma gondii DNA topoisomerase 2, putative 0.0148 0.1325 0.2816
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0111
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0041 0.0256 0.0256
Echinococcus granulosus lamin dm0 0.0029 0.0134 0.0134
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.022 0.022
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0041 0.0256 0.0256
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0041 0.0253 0.0951
Brugia malayi hypothetical protein 0.0141 0.1253 0.205
Onchocerca volvulus 0.0141 0.1253 0.5214
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0037 0.022 0.036
Brugia malayi ecdysteroid receptor 0.0021 0.0062 0.0102
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0387 0.0387
Schistosoma mansoni hypothetical protein 0.0141 0.1253 0.1361
Trypanosoma cruzi NADH dehydrogenase, putative 0.0075 0.0596 0.0774
Brugia malayi neuropeptide F receptor 0.0141 0.1253 0.205
Echinococcus multilocularis peregrin 0.0031 0.0157 0.0157
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0075 0.0596 0.2238
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0283 0.0307
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0086 0.071 0.2666
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.022 0.0239
Leishmania major calmodulin, putative 0.0026 0.0108 0.014
Loa Loa (eye worm) blistered cuticle protein 3 0.0077 0.0616 0.1096
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0041 0.0256 0.0256
Leishmania major calmodulin, putative 0.0026 0.0108 0.014
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0074 0.0584 0.0955
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0075 0.0596 0.0596
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0037 0.022 0.0239
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0054 0.0088
Loa Loa (eye worm) hypothetical protein 0.0028 0.0129 0.0229
Schistosoma mansoni voltage-gated cation channel 0.0136 0.1209 0.1314
Brugia malayi hypothetical protein 0.0042 0.0265 0.0434
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0307 0.0334
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0075 0.0596 0.2238
Loa Loa (eye worm) melatonin receptor type 1A 0.0141 0.1253 0.2227
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0062 0.0068
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0134 0.0238
Schistosoma mansoni tyrosine kinase 0.0052 0.0364 0.0395
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0037 0.022 0.036
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0038 0.0126
Brugia malayi hypothetical protein 0.0141 0.1253 0.205
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0054 0.0095
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0546 0.0709
Echinococcus granulosus epidermal growth factor receptor 0.0086 0.0707 0.0707
Echinococcus granulosus rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Schistosoma mansoni cpg binding protein 0.0032 0.017 0.0184
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0282 0.2663 1
Echinococcus granulosus allatostatin A receptor 0.0141 0.1253 0.1253
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0052 0.0364 0.0364
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0688 0.672 0.672
Brugia malayi Metabotropic glutamate receptor precursor. 0.0024 0.0091 0.0148
Echinococcus multilocularis voltage gated potassium channel 0.0037 0.022 0.022
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0546 0.0593
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0387 0.0503
Schistosoma mansoni rab6-interacting 0.0042 0.0265 0.0288
Schistosoma mansoni polycystin 1-related 0.0042 0.0265 0.0288
Echinococcus granulosus neuropeptides capa receptor 0.0141 0.1253 0.1253
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0239 0.0239
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.0659 0.1399
Brugia malayi Cytochrome P450 family protein 0.0021 0.0054 0.0088
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0075 0.0596 0.2026
Schistosoma mansoni hypothetical protein 0.0179 0.1639 0.178
Loa Loa (eye worm) glutamate receptor 0.0024 0.0091 0.0161
Brugia malayi hypothetical protein 0.0024 0.0091 0.0148
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.2577 0.8776
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0062 0.0102
Echinococcus granulosus neuropeptide receptor A26 0.0628 0.6112 0.6112
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0073 0.0582 0.0582
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0358 0.0586
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.0217 0.0217
Echinococcus multilocularis rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0141 0.1253 0.1361
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0075 0.0596 0.1266
Brugia malayi Pre-SET motif family protein 0.0221 0.2054 0.336
Leishmania major hypothetical protein, conserved 0.0027 0.0115 0.015
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0073 0.0582 0.0582
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0035 0.0198 0.0745
Chlamydia trachomatis endonuclease IV 0.0081 0.0659 0.2473
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0041 0.0256 0.0256
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0075 0.0596 0.0774
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0062 0.0111
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0026 0.0108 0.0108
Loa Loa (eye worm) G-protein coupled receptor 0.0141 0.1253 0.2227
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0048 0.0158
Echinococcus multilocularis calmodulin 0.0026 0.0108 0.0108
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0016 0.0034
Schistosoma mansoni sodium/chloride dependent transporter 0.0256 0.2403 0.2611
Giardia lamblia Glutamate synthase 0.0075 0.0596 0.1948
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0546 0.0971
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0283 0.0502
Echinococcus granulosus rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Schistosoma mansoni hypothetical protein 0.0051 0.0358 0.0389
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0141 0.1253 0.1361
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0387 0.0503
Echinococcus multilocularis allatostatin A receptor 0.0141 0.1253 0.1253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.013 0.0438
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0096 0.036
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0092
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0062 0.0467 0.1753
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0239 0.0239
Echinococcus granulosus g protein coupled receptor 0.0141 0.1253 0.1253
Schistosoma mansoni metabotropic glutamate receptor 0.0024 0.0091 0.0099
Loa Loa (eye worm) hypothetical protein 0.01 0.0848 0.1507
Echinococcus multilocularis nmda type glutamate receptor 0.0108 0.0924 0.0924
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0136 0.1209 0.1209
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0141 0.1253 0.1253
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Treponema pallidum quinoline 2-oxidoreductase 0.0029 0.014 0.0318
Echinococcus granulosus two pore calcium channel protein 2 0.0037 0.022 0.022
Onchocerca volvulus 0.0026 0.0107 0.0447
Schistosoma mansoni tyrosine kinase 0.0084 0.0686 0.0746
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0148 0.1325 0.2168
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0062 0.0062
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0075 0.0596 0.1586
Brugia malayi PHD-finger family protein 0.0031 0.0157 0.0257
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0141 0.1253 0.1253
Echinococcus granulosus biogenic amine 5HT receptor 0.0937 0.9205 0.9205
Trypanosoma cruzi DNA topoisomerase II, putative 0.014 0.1246 0.1618
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0037 0.022 0.022
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0196 0.1803 0.1803
Trypanosoma cruzi calmodulin, putative 0.0026 0.0108 0.014
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0387 0.1315
Trypanosoma cruzi trypanothione reductase, putative 0.0282 0.2663 0.3459
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Echinococcus multilocularis fmrfamide receptor 0.0141 0.1253 0.1253
Brugia malayi hypothetical protein 0.0027 0.0115 0.0188
Brugia malayi sulfakinin receptor protein 0.0141 0.1253 0.205
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0062 0.0111
Brugia malayi putative neuropeptide receptor 0.0141 0.1253 0.205
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0291 0.0317
Onchocerca volvulus 0.0141 0.1253 0.5214
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0161
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0046 0.0307 0.0307
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0037 0.022 0.0285
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0062 0.0068
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0196 0.1803 0.1803
Schistosoma mansoni neuropeptide F-like receptor 0.0141 0.1253 0.1361
Brugia malayi cation channel family protein 0.0037 0.022 0.036
Plasmodium falciparum calmodulin 0.0026 0.0108 0.0229
Loa Loa (eye worm) hypothetical protein 0.0086 0.0712 0.1265
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0062 0.026
Echinococcus multilocularis potassium voltage gated channel protein 0.0037 0.022 0.022
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0054 0.0391 0.147
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0283 0.06
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0054 0.007
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0016 0.0021
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0282 0.2663 0.5659
Brugia malayi olfactory channel protein osm-9 0.0037 0.0222 0.0364
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1017 1 1
Plasmodium falciparum DNA gyrase subunit B 0.0086 0.071 0.1508
Schistosoma mansoni neuropeptide F-like receptor 0.0141 0.1253 0.1361
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0075 0.0596 0.203
Toxoplasma gondii exonuclease III APE 0.002 0.0048 0.0101
Schistosoma mansoni 60S ribosomal protein L21 0.0041 0.0256 0.0278
Schistosoma mansoni growth hormone secretagogue receptor 0.0141 0.1253 0.1361
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0096 0.036
Echinococcus granulosus neuropeptide receptor 0.0141 0.1253 0.1253
Echinococcus multilocularis NMDA receptor 0.0073 0.0582 0.0582
Brugia malayi AKH receptor 0.0141 0.1253 0.205
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0141 0.1253 0.1253
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0283 0.0283
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1639 0.558
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0223 0.2079 0.7807
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0256 0.2403 0.2611
Brugia malayi larval opioid receptor 0.0141 0.1253 0.205
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.2577 0.8776
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0062 0.0068
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0265 0.0564
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0161
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0157 0.0279
Toxoplasma gondii transporter, cation channel family protein 0.0037 0.022 0.0467
Echinococcus multilocularis short transient receptor potential channel 6 0.0037 0.022 0.022
Plasmodium vivax calmodulin, putative 0.0026 0.0108 0.0229
Trypanosoma brucei ATP-binding cassette protein, putative 0.0018 0.0033 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0032 0.0167 0.0412
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0293 0.1218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Echinococcus multilocularis two pore calcium channel protein 1 0.0037 0.022 0.022
Schistosoma mansoni transient receptor potential channel 0.0037 0.022 0.0239
Schistosoma mansoni calcium-activated potassium channel 0.0037 0.022 0.0239
Mycobacterium ulcerans monoxygenase 0.0075 0.0596 0.2238
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0062 0.0102
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0198 0.0421
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0546 0.186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0167 0.0566
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0042 0.0271 0.0271
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0075 0.0596 0.0774
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.2577 0.8776
Echinococcus multilocularis calmodulin 0.0026 0.0108 0.0108
Schistosoma mansoni tyrosine kinase 0.0086 0.0707 0.0768
Brugia malayi steroid hormone receptor 0.0021 0.0062 0.0102
Schistosoma mansoni lipoxygenase 0.0108 0.0928 0.1008
Echinococcus granulosus hypothetical protein 0.0871 0.8542 0.8542
Leishmania major hypothetical protein, conserved 0.0075 0.0596 0.0774
Echinococcus multilocularis tumor protein p63 0.0358 0.3418 0.3418
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0211 0.0449
Echinococcus granulosus hypothetical protein 0.0037 0.022 0.022
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0136 0.1209 0.1209
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Echinococcus multilocularis glutamate receptor 2 0.0172 0.1561 0.1561
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0227 0.0768
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0151 0.1357 0.3612
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0183 0.1678 0.1678
Schistosoma mansoni lamin 0.0029 0.0134 0.0145
Echinococcus multilocularis rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Mycobacterium tuberculosis Probable reductase 0.0184 0.1689 0.3589
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0008 0.0011
Echinococcus multilocularis sodium leak channel non selective protein 0.0037 0.022 0.022
Brugia malayi hypothetical protein 0.0141 0.1253 0.205
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0037 0.022 0.022
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0042 0.0271 0.0271
Brugia malayi glutamate synthase 0.0075 0.0596 0.0975
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0042 0.0271 0.0295
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0197 0.0197
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.111 0.1973
Echinococcus multilocularis conserved hypothetical protein 0.0037 0.022 0.022
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0043 0.0283 0.0283
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0239 0.031
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0016 0.0016
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0075 0.0596 0.1586
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0062 0.0062
Schistosoma mansoni ap endonuclease 0.002 0.0048 0.0052
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0727 0.119
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0278 0.0278
Onchocerca volvulus 0.0141 0.1253 0.5214
Echinococcus granulosus short transient receptor potential channel 6 0.0037 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0161
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0037 0.022 0.0239
Onchocerca volvulus 0.0079 0.0637 0.2651
Brugia malayi G protein-coupled receptor 0.0141 0.1253 0.205
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0075 0.0596 0.203
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0008 0.0011
Schistosoma mansoni chromobox protein 0.0074 0.0585 0.0635
Brugia malayi Dopamine receptor protein 2 0.0141 0.1253 0.205
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0485 0.0862
Loa Loa (eye worm) hypothetical protein 0.0052 0.0371 0.066
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0546 0.0894
Brugia malayi SRC-1 0.0041 0.0256 0.0418
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0048 0.0101
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0037 0.022 0.036
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1735 0.5908
Brugia malayi hypothetical protein 0.0141 0.1253 0.205
Echinococcus multilocularis serotonin receptor 0.0398 0.3826 0.3826
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0324 0.042
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0062 0.0062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0062 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0227 0.0768
Schistosoma mansoni tyrosine kinase 0.0026 0.0111 0.012
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0546 0.0546
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0075 0.0596 0.0774
Trichomonas vaginalis calmodulin, putative 0.0026 0.0108 0.0362
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0096 0.0125
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0451 0.4346 0.5644
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0676 0.6592 0.8561
Plasmodium vivax glutathione reductase, putative 0.0487 0.4707 1
Entamoeba histolytica disulphide oxidoreductase, putative 0.0075 0.0596 0.203
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0184 0.1689 0.3589
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0177 0.0177
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0008 0.0008
Trichomonas vaginalis DNA topoisomerase II, putative 0.0148 0.1325 0.4512
Onchocerca volvulus 0.0088 0.0727 0.3026
Loa Loa (eye worm) calcium channel 0.0136 0.1209 0.2149
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0024 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0053 0.0376 0.0667
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0008 0.0023
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0032 0.0167 0.0354
Brugia malayi Heterochromatin protein 1 0.0074 0.0585 0.0957
Schistosoma mansoni opsin-like receptor 0.0141 0.1253 0.1361
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0037 0.022 0.036
Echinococcus multilocularis glutamate receptor 2 0.0196 0.1803 0.1803
Schistosoma mansoni hypothetical protein 0.0017 0.0016 0.0017
Mycobacterium ulcerans glutamate synthase subunit beta 0.0075 0.0596 0.2238
Echinococcus granulosus shaker cognate 0.0037 0.022 0.022
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Echinococcus multilocularis rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0171 0.0171
Echinococcus multilocularis tyrosine kinase 0.0026 0.0111 0.0111
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0141 0.1253 0.1361
Mycobacterium ulcerans endonuclease IV 0.0081 0.0659 0.2473
Echinococcus granulosus tyrosine kinase 0.0026 0.0111 0.0111
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0008 0.0014
Trichomonas vaginalis hypothetical protein 0.0223 0.2079 0.708
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0086 0.0707 0.0707
Onchocerca volvulus 0.0141 0.1253 0.5214
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0141 0.1253 0.1361
Loa Loa (eye worm) hypothetical protein 0.0041 0.0256 0.0455
Schistosoma mansoni glutamate synthase 0.0075 0.0596 0.0647
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0075 0.0596 0.1266
Schistosoma mansoni hypothetical protein 0.0017 0.0016 0.0017
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0115 0.015
Brugia malayi hypothetical protein 0.007 0.0546 0.0892
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.2936 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0048 0.0101
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0111
Echinococcus multilocularis voltage dependent calcium channel 0.0136 0.1209 0.1209
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Echinococcus multilocularis neuropeptide receptor 0.0141 0.1253 0.1253
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0111
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0148 0.1325 0.2168
Plasmodium vivax ferrodoxin reductase, putative 0.0075 0.0596 0.1266
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Brugia malayi MH2 domain containing protein 0.0126 0.111 0.1816
Brugia malayi ABC transporter family protein 0.0016 0.0005 0.0009
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0101 0.0858 0.0858
Echinococcus granulosus somatostatin receptor 0.0141 0.1253 0.1253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0227 0.0768
Loa Loa (eye worm) hypothetical protein 0.0031 0.0157 0.0279
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0222 0.0222
Trypanosoma brucei NADH dehydrogenase 0.0075 0.0596 0.0774
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0041 0.0253 0.0951
Onchocerca volvulus DNA topoisomerase 2 homolog 0.01 0.0847 0.3524
Echinococcus multilocularis neuropeptide Y receptor 0.0141 0.1253 0.1253
Loa Loa (eye worm) solute carrier family 6 member 4 0.0256 0.2403 0.4271
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0075 0.0596 0.1266
Schistosoma mansoni biogenic amine receptor 0.0141 0.1253 0.1361
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0283 0.0307
Echinococcus granulosus ATP binding cassette sub family G 0.0018 0.0033 0.0033
Brugia malayi putative neuropeptide receptor NPR1 0.0141 0.1253 0.205
Brugia malayi hypothetical protein 0.0043 0.0283 0.0462
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0134 0.0238
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.022 0.022
Schistosoma mansoni hypothetical protein 0.0036 0.0209 0.0227
Onchocerca volvulus 0.0252 0.236 0.9822
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0018 0.0033 0.0043
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.022 0.022
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0265 0.0265
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0062 0.0068
Mycobacterium ulcerans NADH dehydrogenase 0.0075 0.0596 0.2238
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0096 0.0167
Onchocerca volvulus 0.0051 0.0358 0.1492
Chlamydia trachomatis glutamine binding protein 0.0041 0.0253 0.0951
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0324 0.0575
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0008 0.0013
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0546 0.0709
Echinococcus multilocularis transient receptor potential gamma protein 0.0037 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0502
Schistosoma mansoni alpha-1 adrenergic receptor 0.0141 0.1253 0.1361
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0096 0.0204
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0196 0.1803 0.1803
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0062 0.0257
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0787 0.77 1
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0062 0.0062
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0202 0.0429
Echinococcus multilocularis rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0141 0.1253 0.1361
Echinococcus granulosus rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Toxoplasma gondii hypothetical protein 0.0019 0.0036 0.0076
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0282 0.2663 0.3459
Brugia malayi hypothetical protein 0.0141 0.1253 0.205
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0211 0.0449
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0133 0.0448
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0136 0.1209 0.1209
Echinococcus multilocularis conserved hypothetical protein 0.073 0.7138 0.7138
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0037 0.022 0.036
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0073 0.0582 0.0582
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0282 0.2663 0.4357
Echinococcus multilocularis tyrosine protein kinase Srms 0.0037 0.0217 0.0217
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0177 0.0177
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0157 0.0333
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0016 0.0016
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0046 0.0307 0.0502
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0727 0.0727
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0171 0.0171
Schistosoma mansoni inositol monophosphatase 0.0039 0.0239 0.026
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Echinococcus granulosus calmodulin 0.0026 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0042 0.0265 0.0472
Schistosoma mansoni hypothetical protein 0.0031 0.0157 0.017
Loa Loa (eye worm) hypothetical protein 0.0032 0.0171 0.0304
Loa Loa (eye worm) hypothetical protein 0.0026 0.0108 0.0191
Toxoplasma gondii hypothetical protein 0.0037 0.022 0.0467
Leishmania major calmodulin, putative 0.0026 0.0108 0.014
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0043 0.0283 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.013 0.0438
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0018 0.0033 0.0124
Loa Loa (eye worm) voltage-gated potassium channel 0.0037 0.022 0.0391
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0111
Schistosoma mansoni ATP-binding cassette transporter 0.0172 0.1565 0.17
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0787 0.77 1
Echinococcus granulosus tm gpcr rhodopsin 0.0688 0.672 0.672
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0042 0.0271 0.0271
Schistosoma mansoni tyrosine kinase 0.0041 0.0256 0.0278
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0075 0.0596 0.1586
Echinococcus granulosus glutamate receptor 2 0.0122 0.107 0.107
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0223 0.2079 0.4418
Loa Loa (eye worm) hypothetical protein 0.0579 0.5626 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0111
Schistosoma mansoni hypothetical protein 0.0141 0.1253 0.1361
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0016 0.0016
Onchocerca volvulus 0.0021 0.0062 0.026
Echinococcus granulosus tyrosine kinase 0.0037 0.0217 0.0217
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0096 0.0204
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0141 0.1253 0.1361
Loa Loa (eye worm) voltage-gated potassium channel 0.0037 0.022 0.0391
Schistosoma mansoni hypothetical protein 0.0037 0.022 0.0239
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.022 0.022
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0062 0.0101
Brugia malayi Dopamine receptor 0.0141 0.1253 0.205
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0141 0.1253 0.2227
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.0271 0.0295
Plasmodium falciparum glutathione reductase 0.0282 0.2663 0.5659
Onchocerca volvulus 0.0044 0.0291 0.1212
Loa Loa (eye worm) adenylyl cyclase 3 0.0082 0.0672 0.1194
Echinococcus granulosus G protein coupled receptor 139 0.0141 0.1253 0.1253
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0075 0.0596 0.0596
Echinococcus multilocularis calmodulin 0.0026 0.0107 0.0107
Brugia malayi Thioredoxin reductase 0.0487 0.4707 0.77
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0225 0.2095 0.3723
Brugia malayi hypothetical protein 0.0042 0.0265 0.0434
Toxoplasma gondii hypothetical protein 0.0043 0.0283 0.06
Brugia malayi Adenylyl cyclase protein 0.0082 0.0672 0.1099
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0075 0.0596 0.1266
Echinococcus granulosus glutamate NMDA receptor subunit 0.0347 0.3311 0.3311
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0054 0.007
Echinococcus multilocularis G-protein coupled receptor, putative 0.0141 0.1253 0.1253
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0043 0.0283 0.0283
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0171 0.0171
Loa Loa (eye worm) G-protein coupled receptor 0.0141 0.1253 0.2227
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0037 0.022 0.022
Schistosoma mansoni protein kinase 0.003 0.0146 0.0158
Echinococcus multilocularis sodium and chloride dependent glycine 0.0043 0.0283 0.0283
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0041 0.0256 0.0256
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0075 0.0596 0.2238
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0171 0.0186
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0324 0.0324
Trypanosoma cruzi trypanothione reductase, putative 0.0487 0.4707 0.6112
Loa Loa (eye worm) hypothetical protein 0.0037 0.0222 0.0395
Plasmodium falciparum enoyl-acyl carrier reductase 0.0223 0.2079 0.4418
Brugia malayi Blistered cuticle protein 3 0.0077 0.0616 0.1008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0105 0.0354
Trichomonas vaginalis set domain proteins, putative 0.0251 0.2358 0.8029
Mycobacterium ulcerans ferredoxin reductase 0.0075 0.0596 0.2238
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.2936 1
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0024 0.0091 0.0091
Loa Loa (eye worm) thioredoxin reductase 0.0487 0.4707 0.8365
Echinococcus multilocularis neuropeptide Y receptor 0.0141 0.1253 0.1253
Plasmodium falciparum glutathione reductase 0.0487 0.4707 1
Brugia malayi cation channel family protein 0.0037 0.022 0.036
Echinococcus granulosus rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Echinococcus granulosus CalModulin family member cmd 1 0.0026 0.0108 0.0108
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0585 0.1989
Echinococcus granulosus neuropeptide Y receptor 0.0141 0.1253 0.1253
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0062 0.0102
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0282 0.2663 1
Schistosoma mansoni tyrosine kinase 0.0052 0.0364 0.0395
Schistosoma mansoni tyrosine kinase 0.0084 0.0686 0.0746
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0787 0.77 1
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0136 0.1209 0.1209
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0223 0.2079 0.4418
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0073 0.0582 0.0582
Brugia malayi ORL1-like opioid receptor 0.0141 0.1253 0.205
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0081 0.0659 0.1753
Schistosoma mansoni survival motor neuron protein 0.0051 0.0358 0.0389
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0096 0.0125
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0008 0.0011
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0223 0.2079 0.4418
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0487 0.4707 1
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1639 0.558
Brugia malayi Melatonin receptor type 1A 0.0141 0.1253 0.205
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0546 0.0546
Trypanosoma brucei DNA topoisomerase ii 0.0166 0.1506 0.1956
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0064
Brugia malayi hypothetical protein 0.025 0.2347 0.3839
Leishmania major trypanothione reductase 0.0487 0.4707 0.6112
Echinococcus multilocularis survival motor neuron protein 1 0.025 0.2347 0.2347
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0239 0.026
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0075 0.0596 0.2238
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0062 0.0102
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0111
Brugia malayi chromobox protein homolog 3 0.0041 0.0261 0.0428
Echinococcus granulosus insulin receptor 0.0052 0.0364 0.0364
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0227 0.0295
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0136 0.1209 0.1209
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0502
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0601 0.5851 0.7598
Trichomonas vaginalis glutathione reductase, putative 0.0282 0.2663 0.907
Echinococcus multilocularis lamin dm0 0.0029 0.0134 0.0134
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0062 0.0062
Echinococcus granulosus dnaJ subfamily B 0.0433 0.4169 0.4169
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0141 0.1253 0.1361
Echinococcus granulosus serotonin transporter 0.0256 0.2403 0.2403
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0075 0.0596 0.2026
Trypanosoma brucei protein kinase, putative 0.0054 0.0387 0.0503
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0146 0.0259
Echinococcus multilocularis thioredoxin glutathione reductase 0.0487 0.4707 0.4707
Loa Loa (eye worm) hypothetical protein 0.0026 0.0111 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0008 0.0023
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0387 0.0688
Giardia lamblia Thioredoxin reductase 0.0075 0.0596 0.1948
Echinococcus granulosus ryanodine receptor 44f 0.0037 0.022 0.022
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0166 0.1506 0.1956
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0016 0.0025
Echinococcus multilocularis sex peptide receptor 0.0141 0.1253 0.1253
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0075 0.0596 0.203
Echinococcus multilocularis potassium voltage gated channel protein 0.0037 0.022 0.022
Echinococcus granulosus chromobox protein 1 0.0074 0.0585 0.0585
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0062 0.0068
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0048 0.0179
Echinococcus granulosus receptor type guanylyl cyclase 0.003 0.0146 0.0146
Brugia malayi G protein-coupled receptor F59B2.13 0.0141 0.1253 0.205
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0075 0.0596 0.1266
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0075 0.0596 0.203
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Loa Loa (eye worm) hypothetical protein 0.0454 0.4377 0.7779
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0018 0.0033 0.007
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0073 0.0095
Trypanosoma brucei calmodulin 0.0026 0.0108 0.014
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0197 0.0197
Toxoplasma gondii endonuclease IV APN 0.0081 0.0659 0.1399
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0265 0.0472
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0016 0.0016
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0371 0.0403
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0043 0.0283 0.0283
Schistosoma mansoni hypothetical protein 0.0072 0.057 0.0619
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0037 0.022 0.036
Plasmodium falciparum amino acid transporter, putative 0.0043 0.0283 0.06
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0016 0.0034
Entamoeba histolytica hypothetical protein 0.0024 0.0091 0.0309
Echinococcus multilocularis glutamate receptor NMDA 0.0083 0.0682 0.0682
Loa Loa (eye worm) hypothetical protein 0.006 0.0449 0.0799
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0282 0.2663 0.5659
Brugia malayi Serotonin receptor 0.0141 0.1253 0.205
Brugia malayi Cyclic-nucleotide gated cation channel 0.0042 0.0271 0.0444
Schistosoma mansoni rab6-interacting 0.0042 0.0265 0.0288
Trichomonas vaginalis apoptosis inducing factor, putative 0.0075 0.0596 0.2026
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0062 0.0068
Schistosoma mansoni tyrosine kinase 0.0026 0.0111 0.012
Onchocerca volvulus 0.0256 0.2403 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0283 0.0462
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0239 0.031
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0089 0.0736 0.0736
Echinococcus multilocularis rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0282 0.2663 0.5659
Echinococcus granulosus glutamate receptor NMDA 0.0083 0.0682 0.0682
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0062 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Brugia malayi Tachykinin-like peptides receptor 99D 0.0141 0.1253 0.205
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0075 0.0596 0.0596
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0075 0.0596 0.203
Trypanosoma brucei DNA topoisomerase II beta, putative 0.014 0.1246 0.1618
Plasmodium vivax thioredoxin reductase, putative 0.0487 0.4707 1
Schistosoma mansoni vesicular amine transporter 0.0037 0.022 0.0239
Echinococcus granulosus tm gpcr rhodopsin 0.0141 0.1253 0.1253
Trypanosoma cruzi NADH dehydrogenase, putative 0.0075 0.0596 0.0774
Onchocerca volvulus Alhambra homolog 0.0031 0.0157 0.0653
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0018 0.0033 0.0036
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0141 0.1253 0.1253
Echinococcus granulosus tyrosine protein kinase Src42A 0.0041 0.0256 0.0256
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0141 0.1253 0.1253
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0324 0.042
Echinococcus multilocularis dnaJ subfamily B 0.0433 0.4169 0.4169
Brugia malayi Inositol-1 0.0039 0.0239 0.0391
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0075 0.0596 0.0975
Onchocerca volvulus 0.0141 0.1253 0.5214
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0062 0.0467 0.0992
Echinococcus granulosus voltage gated potassium channel 0.0037 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0075 0.0596 0.0596
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0062 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0265 0.0265
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0115 0.0245
Echinococcus granulosus nmda type glutamate receptor 0.0108 0.0924 0.0924
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0141 0.1253 0.1361
Echinococcus granulosus transcription factor Dp 1 0.004 0.0253 0.0253
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0324 0.042
Treponema pallidum hypothetical protein 0.003 0.0146 0.0342
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0211 0.0274
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0282 0.2663 0.2893
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0387 0.0421
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Brugia malayi hypothetical protein 0.0037 0.022 0.036
Brugia malayi nuclear receptor NHR-88 0.0021 0.0062 0.0102
Treponema pallidum sodium- and chloride- dependent transporter 0.0256 0.2403 0.8154
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0157 0.0333
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0042 0.0271 0.0271
Onchocerca volvulus 0.0029 0.0134 0.0557
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0062 0.0467 0.1753
Treponema pallidum fructose-bisphosphate aldolase 0.0309 0.2936 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0141 0.1253 0.1361
Schistosoma mansoni histamine h1 receptor 0.0141 0.1253 0.1361
Plasmodium vivax DNA gyrase subunit B, putative 0.0086 0.071 0.1508
Plasmodium falciparum DNA gyrase subunit A 0.0032 0.0167 0.0354
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0075 0.0596 0.0774
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0016 0.0028
Schistosoma mansoni two-pore calcium channel 0.0037 0.022 0.0239
Echinococcus granulosus hyperpolarization activated cyclic 0.0042 0.0271 0.0271
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0075 0.0596 0.2238
Brugia malayi Cytochrome P450 family protein 0.0021 0.0054 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.2577 0.8776
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0048 0.0162
Schistosoma mansoni lamin 0.0029 0.0134 0.0145
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0048 0.0179
Mycobacterium ulcerans epimerase 0.0021 0.0062 0.0232
Loa Loa (eye worm) hypothetical protein 0.039 0.3738 0.6644
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0062 0.0111
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0211 0.0449
Echinococcus granulosus glutamate receptor subunit protein glur 0.0073 0.0582 0.0582
Loa Loa (eye worm) hypothetical protein 0.0041 0.0261 0.0465
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0223 0.2079 0.7807
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0096 0.0255
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0096 0.036
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0037 0.022 0.0467
Brugia malayi jmjC domain containing protein 0.0101 0.0858 0.1403
Schistosoma mansoni neuropeptide receptor 0.0141 0.1253 0.1361
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0126
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Echinococcus granulosus neuropeptides capa receptor 0.0141 0.1253 0.1253
Echinococcus multilocularis two pore calcium channel protein 2 0.0037 0.022 0.022
Echinococcus multilocularis ryanodine receptor 44f 0.0037 0.022 0.022
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0324 0.0352
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0062 0.0062
Onchocerca volvulus 0.0141 0.1253 0.5214
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0037 0.022 0.022
Echinococcus multilocularis potassium voltage gated channel protein 0.0037 0.022 0.022
Schistosoma mansoni hypothetical protein 0.0141 0.1253 0.1361
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0115 0.0245
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0387 0.0503
Toxoplasma gondii thioredoxin reductase 0.0487 0.4707 1
Echinococcus multilocularis ATP binding cassette sub family G 0.0018 0.0033 0.0033
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0387 0.0387
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0016 0.0034
Echinococcus multilocularis G protein coupled receptor 139 0.0141 0.1253 0.1253
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0043 0.0283 0.0283
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0018 0.0033 0.0043
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.022 0.0239
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0062 0.0111
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.0271 0.0295
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0141 0.1253 0.2227
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0141 0.1253 0.2227
Trypanosoma brucei ABC transporter, putative 0.0018 0.0033 0.0043
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0309 0.2936 1
Echinococcus multilocularis 0.0049 0.0337 0.0337
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0184 0.1689 0.3589
Brugia malayi Serotonin receptor 0.0628 0.6112 1
Echinococcus multilocularis calmodulin 0.0026 0.0108 0.0108
Brugia malayi Receptor family ligand binding region containing protein 0.003 0.0146 0.0239
Trichomonas vaginalis aldehyde oxidase, putative 0.0183 0.1679 0.5717
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0282 0.2663 0.5659
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0073 0.0582 0.0582
Schistosoma mansoni disulfide oxidoreductase 0.0075 0.0596 0.0647
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.0271 0.092
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0062 0.0062
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0387 0.0823
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0074 0.0584 0.0584
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0008 0.0009
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0491 0.4751 0.4751
Loa Loa (eye worm) glutamate receptor 1 0.0172 0.1561 0.2775
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0256 0.0256
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0676 0.6592 0.8561
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0161
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0038 0.0233 0.0619
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1639 0.558
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0081 0.0659 0.1399
Echinococcus granulosus metabotropic glutamate receptor 5 0.0024 0.0091 0.0091
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0601 0.5851 0.7598
Plasmodium falciparum transporter, putative 0.0043 0.0283 0.06
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0115 0.015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0038 0.0126
Echinococcus granulosus 7TM GPCR rhodopsin 0.0141 0.1253 0.1253
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0016 0.0034
Brugia malayi glutathione reductase 0.0487 0.4707 0.77
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0086 0.071 0.2293
Schistosoma mansoni glutamate receptor AMPA 0.0172 0.1561 0.1696
Brugia malayi G-protein coupled receptor 0.0141 0.1253 0.205
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.014 0.1246 0.1618
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0075 0.0596 0.2026
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0261 0.0887
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0254 0.0862
Brugia malayi bZIP transcription factor family protein 0.0089 0.0736 0.1204
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0075 0.0596 0.0596
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0282 0.2663 0.3459
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0037 0.022 0.022
Mycobacterium ulcerans hypothetical protein 0.0075 0.0596 0.2238
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0048 0.0062
Loa Loa (eye worm) hypothetical protein 0.0579 0.5626 1
Brugia malayi Augmenter of liver regeneration 0.0036 0.0211 0.0346
Onchocerca volvulus 0.0052 0.0371 0.1545
Echinococcus granulosus adenylate cyclase 9 0.0082 0.0672 0.0672
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0016 0.0016
Brugia malayi ion channel NompC 0.0037 0.022 0.036
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0075 0.0596 0.1266
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0086 0.071 0.1508
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.0391
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0265 0.0265
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0002 0.0003
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0075 0.0596 0.0774
Echinococcus multilocularis potassium large conductance calcium activated 0.0037 0.022 0.022
Onchocerca volvulus Calmodulin homolog 0.0026 0.0108 0.0448
Trypanosoma cruzi calmodulin, putative 0.0026 0.0108 0.014
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.01 0.0847 0.3524
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0676 0.6592 0.8561
Echinococcus multilocularis rhodopsin orphan GPCR 0.0141 0.1253 0.1253
Echinococcus multilocularis hyperpolarization activated cyclic 0.0042 0.0271 0.0271
Schistosoma mansoni hypothetical protein 0.0042 0.0265 0.0288
Leishmania major hypothetical protein, unknown function 0.0037 0.022 0.0285
Treponema pallidum hypothetical protein 0.0025 0.0094 0.0161
Loa Loa (eye worm) ABC transporter 0.0016 0.0005 0.0009
Brugia malayi nuclear hormone receptor 0.0021 0.0062 0.0102
Leishmania major hypothetical protein, conserved 0.0075 0.0596 0.0774
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0062 0.026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0006 0.0017
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0086 0.071 0.1508
Schistosoma mansoni ap endonuclease 0.002 0.0048 0.0052
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0018 0.0033 0.0124
Treponema pallidum oxidoreductase 0.0075 0.0596 0.1898
Brugia malayi hypothetical protein 0.0141 0.1253 0.205
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0035 0.0198 0.0422
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0392 0.3757 1
Entamoeba histolytica ABC transporter, putative 0.0018 0.0033 0.0113
Brugia malayi hypothetical protein 0.0141 0.1253 0.205
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0037 0.022 0.036
Trichomonas vaginalis mercuric reductase, putative 0.0282 0.2663 0.907
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0265 0.0265
Trypanosoma cruzi calmodulin 0.0026 0.0108 0.014
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0075 0.0596 0.0774
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Loa Loa (eye worm) hypothetical protein 0.0043 0.0283 0.0502
Mycobacterium tuberculosis Probable oxidoreductase 0.0392 0.3757 0.7982
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0074 0.0584 0.1038
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0141 0.1253 0.1253
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0028
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0062 0.0062
Loa Loa (eye worm) glutathione reductase 0.0487 0.4707 0.8365
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0141 0.1253 0.1361
Loa Loa (eye worm) hypothetical protein 0.0042 0.0265 0.0472
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0062 0.026
Brugia malayi Doublecortin family protein 0.0042 0.0265 0.0434
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0037 0.022 0.0915
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0111
Toxoplasma gondii transporter, cation channel family protein 0.0056 0.0407 0.0864
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Loa Loa (eye worm) hypothetical protein 0.0141 0.1253 0.2227
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0096 0.0204
Echinococcus granulosus g protein coupled receptor 0.0141 0.1253 0.1253
Trypanosoma brucei C-8 sterol isomerase, putative 0.039 0.3738 0.4855
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0075 0.0596 0.2026
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0042 0.0271 0.0271
Chlamydia trachomatis thioredoxin reductase 0.0075 0.0596 0.2238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0105 0.0354
Echinococcus granulosus neuropeptide Y receptor 0.0141 0.1253 0.1253
Loa Loa (eye worm) hypothetical protein 0.01 0.0848 0.1507
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0036 0.0209 0.0272
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0016 0.0021
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0062 0.0102
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0676 0.6592 0.8561
Plasmodium falciparum phd finger protein, putative 0.0031 0.0157 0.0333
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0037 0.022 0.036
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0062 0.0102
Echinococcus granulosus neuropeptide receptor 0.0141 0.1253 0.1253
Echinococcus multilocularis neuropeptide receptor 0.0141 0.1253 0.1253
Echinococcus granulosus peregrin 0.0031 0.0157 0.0157
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0222 0.0222
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0324 0.1102
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0062 0.0102
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0256 0.0278
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0037 0.022 0.022
Echinococcus multilocularis chromobox protein 1 0.0074 0.0585 0.0585
Loa Loa (eye worm) hypothetical protein 0.0053 0.0377 0.067
Schistosoma mansoni cpg binding protein 0.0032 0.017 0.0184
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0136 0.1209 0.2149
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0092
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0022 0.007

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA ChEMBL. 18457948
Activity (binding) 0 Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA ChEMBL. 18457948
Ki (binding) = 1 nM Inhibition of Mycobacterium tuberculosis H37RV InhA ChEMBL. 18457948
Ki (binding) = 1 nM Inhibition of Mycobacterium tuberculosis H37RV InhA ChEMBL. 18457948
MIC90 (functional) = 100 ug ml-1 Antimicrobial activity against Mycobacterium tuberculosis H37RV ChEMBL. 18457948
MIC90 (functional) = 100 ug ml-1 Antimicrobial activity against Mycobacterium tuberculosis H37RV ChEMBL. 18457948

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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