Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.02 | 0.02 |
Schistosoma mansoni | jun-related protein | 0.0073 | 0.1355 | 0.1355 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0052 | 0.0378 | 0.0378 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0087 | 0.2025 | 0.4783 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0257 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.011 | 0.3091 | 0.3091 |
Plasmodium falciparum | transporter, putative | 0.0044 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.011 | 0.3091 | 0.3091 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0059 | 0.0705 | 0.0705 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0076 | 0.151 | 0.151 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0052 | 0.0378 | 0.0378 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0052 | 0.0378 | 0.0378 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0669 | 0.0669 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | nuclear hormone receptor | 0.0052 | 0.0378 | 0.0378 |
Plasmodium vivax | amine transporter, putative | 0.0044 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.151 | 0.151 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | gabp alpha | 0.0076 | 0.151 | 0.151 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.2024 | 0.2024 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.1064 | 0.1064 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0052 | 0.0378 | 0.0378 |
Onchocerca volvulus | Bile acid receptor homolog | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | coup transcription factor | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.1064 | 0.1064 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0058 | 0.0669 | 0.0669 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0058 | 0.0669 | 0.0669 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | nuclear receptor RXR | 0.0058 | 0.0669 | 0.0669 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | fli-1 protein | 0.023 | 0.8746 | 0.8746 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.02 | 0.02 |
Schistosoma mansoni | nuclear hormone receptor | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | hypothetical protein | 0.0058 | 0.0669 | 0.0669 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0052 | 0.0378 | 0.0378 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0052 | 0.0378 | 0.0378 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0052 | 0.0378 | 0.0378 |
Plasmodium falciparum | amino acid transporter, putative | 0.0044 | 0 | 0.5 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 | 0.0062 | 0.0869 | 0.1125 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.011 | 0.3091 | 0.3091 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.02 | 0.02 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0052 | 0.0378 | 0.0378 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | DR-78 | 0.0052 | 0.0378 | 0.0378 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0052 | 0.0378 | 0.0378 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.02 | 0.02 |
Schistosoma mansoni | nuclear receptor | 0.0052 | 0.0378 | 0.0378 |
Brugia malayi | conserved hypotetical protein | 0.0052 | 0.0378 | 0.0378 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | lipoxygenase | 0.0059 | 0.0705 | 0.0705 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0044 | 0 | 0.5 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0257 | 1 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0052 | 0.0378 | 0.0378 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.1064 | 0.1064 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0044 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0058 | 0.0669 | 0.0669 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.1355 | 0.1355 |
Brugia malayi | nuclear receptor RXR | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.3091 | 0.3091 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.1064 | 0.1064 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0058 | 0.0669 | 0.0669 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.011 | 0.3091 | 0.3091 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.011 | 0.3091 | 0.3091 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | hypothetical protein | 0.0058 | 0.0669 | 0.0669 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0052 | 0.0378 | 0.0378 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (large chain) | 0.0087 | 0.2025 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.011 | 0.3091 | 0.3091 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0052 | 0.0378 | 0.0378 |
Trichomonas vaginalis | aldehyde oxidase, putative | 0.0184 | 0.6587 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.011 | 0.3091 | 0.3091 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0184 | 0.6587 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0669 | 0.0669 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.011 | 0.3091 | 0.3091 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0052 | 0.0378 | 0.0378 |
Brugia malayi | steroid hormone receptor | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0669 | 0.0669 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.011 | 0.3091 | 0.3091 |
Onchocerca volvulus | 0.0257 | 1 | 1 | |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0052 | 0.0378 | 0.0378 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0076 | 0.151 | 0.151 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0044 | 0 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0058 | 0.0669 | 0.0669 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.1064 | 0.1064 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0089 | 0.2139 | 0.2139 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.011 | 0.3091 | 0.3091 |
Echinococcus granulosus | jun protein | 0.0089 | 0.2139 | 0.2139 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.1064 | 0.1064 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 | 0.0087 | 0.2025 | 0.4783 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.151 | 0.151 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.1064 | 0.1064 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.011 | 0.3091 | 0.3091 |
Echinococcus granulosus | serotonin transporter | 0.0257 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.011 | 0.3091 | 0.3091 |
Onchocerca volvulus | 0.0052 | 0.0378 | 0.0378 | |
Loa Loa (eye worm) | steroid hormone receptor | 0.011 | 0.3091 | 0.3091 |
Echinococcus granulosus | FTZ F1 alpha | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 1 | 1 |
Schistosoma mansoni | ets-related | 0.023 | 0.8746 | 0.8746 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0994 | 0.0994 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase medium chain CoxM | 0.0062 | 0.0869 | 0.1125 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.011 | 0.3091 | 0.3091 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0184 | 0.6587 | 0.5 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0052 | 0.0378 | 0.0378 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.011 | 0.3091 | 0.3091 |
Echinococcus multilocularis | FTZ F1 alpha | 0.011 | 0.3091 | 0.3091 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0257 | 1 | 0.5 |
Brugia malayi | tailless protein | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.011 | 0.3091 | 0.3091 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | nuclear receptor NHR-88 | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | nuclear hormone receptor | 0.0052 | 0.0378 | 0.0378 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.011 | 0.3091 | 0.3091 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.3091 | 0.3091 |
Mycobacterium ulcerans | carbon monoxide dehydrogenase | 0.0122 | 0.3673 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.011 | 0.3091 | 0.3091 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Onchocerca volvulus | 0.011 | 0.3091 | 0.3091 | |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0052 | 0.0378 | 0.0378 |
Brugia malayi | nuclear hormone receptor | 0.0052 | 0.0378 | 0.0378 |
Toxoplasma gondii | hypothetical protein | 0.0044 | 0 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.02 | 0.02 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0052 | 0.0378 | 0.0378 |
Brugia malayi | Fli-1 protein | 0.023 | 0.8746 | 0.8746 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.011 | 0.3091 | 0.3091 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0058 | 0.0669 | 0.0669 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0052 | 0.0378 | 0.0378 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | bZIP transcription factor family protein | 0.0089 | 0.2139 | 0.2139 |
Brugia malayi | nuclear receptor NHR-88 | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Plasmodium vivax | hypothetical protein, conserved | 0.0044 | 0 | 0.5 |
Brugia malayi | ecdysone receptor | 0.0052 | 0.0378 | 0.0378 |
Schistosoma mansoni | thyroid hormone receptor | 0.011 | 0.3091 | 0.3091 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0059 | 0.0705 | 0.0705 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0669 | 0.0669 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0052 | 0.0385 | 0.0385 |
Brugia malayi | hypothetical protein | 0.007 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Echinococcus multilocularis | jun protein | 0.0089 | 0.2139 | 0.2139 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.1064 | 0.1064 |
Brugia malayi | ecdysteroid receptor | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0257 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 1 | 1 |
Echinococcus multilocularis | serotonin transporter | 0.0257 | 1 | 1 |
Loa Loa (eye worm) | serotonin transporter b | 0.0257 | 1 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0052 | 0.0385 | 0.0385 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | nuclear receptor | 0.0052 | 0.0378 | 0.0378 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0089 | 0.2139 | 0.2139 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0257 | 1 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0044 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0052 | 0.0378 | 0.0378 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.011 | 0.3091 | 0.3091 |
Onchocerca volvulus | 0.0052 | 0.0378 | 0.0378 | |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0076 | 0.151 | 0.151 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0058 | 0.0669 | 0.0669 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | RNA binding protein | 0.0066 | 0.1064 | 0.1064 |
Schistosoma mansoni | thyroid hormone receptor | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.3091 | 0.3091 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Toxoplasma gondii | hypothetical protein | 0.0044 | 0 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.011 | 0.3091 | 0.3091 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.02 | 0.02 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0052 | 0.0378 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0669 | 0.0669 |
Brugia malayi | nuclear receptor NHR-67 | 0.0052 | 0.0378 | 0.0378 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.011 | 0.3091 | 0.3091 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.02 | 0.02 |
Onchocerca volvulus | 0.007 | 0.124 | 0.124 | |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0378 | 0.0378 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.02 | 0.02 |
Schistosoma mansoni | zinc finger protein | 0.0052 | 0.0378 | 0.0378 |
Brugia malayi | nuclear hormone receptor | 0.011 | 0.3091 | 0.3091 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.02 | 0.02 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | 0 | Induction of p21 expression in human U937 cells at 5 uM after 24 hrs | ChEMBL. | 18381238 |
Activity (functional) | = 30.3 % | Induction of granulocytic differentiation in human U937 cells assessed as CD11c expression at 5 uM after 30 hrs | ChEMBL. | 18381238 |
Activity (functional) | = 30.3 % | Induction of granulocytic differentiation in human U937 cells assessed as CD11c expression at 5 uM after 30 hrs | ChEMBL. | 18381238 |
Activity (binding) | = 84.7 % | Inhibition of human HDAC1 in U937 cells assessed as residual activity at 5 uM | ChEMBL. | 18381238 |
Activity (binding) | = 84.7 % | Inhibition of human HDAC1 in U937 cells assessed as residual activity at 5 uM | ChEMBL. | 18381238 |
Activity (binding) | = 97 % | Inhibition of human HDAC4 in U937 cells assessed as residual activity at 5 uM | ChEMBL. | 18381238 |
Activity (binding) | = 97 % | Inhibition of human HDAC4 in U937 cells assessed as residual activity at 5 uM | ChEMBL. | 18381238 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.