Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0165 | 0.0588 | 0.1943 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.014 | 0.0489 | 0.832 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.005 | 0.0121 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0045 | 0.0362 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0038 | 0.0072 | 0.058 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Giardia lamblia | CDC8 | 0.0142 | 0.0497 | 0.0497 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0325 | 0.1239 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0189 | 0.0625 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Schistosoma mansoni | ap endonuclease | 0.0038 | 0.0072 | 0.0108 |
Trypanosoma brucei | cytidine deaminase | 0.0055 | 0.0142 | 0.0468 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0189 | 0.0625 |
Leishmania major | hypothetical protein, conserved | 0.005 | 0.0121 | 0.0399 |
Trichomonas vaginalis | cytidine deaminase, putative | 0.0055 | 0.0142 | 0.0468 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0038 | 0.0072 | 0.0238 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.014 | 0.0489 | 0.1617 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0045 | 0.0068 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0067 | 0.0189 | 0.0625 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0075 | 0.0224 | 0.074 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0038 | 0.0072 | 0.1223 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0283 | 0.0427 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0075 | 0.0224 | 0.074 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0325 | 0.1239 | 0.4095 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.0624 | 0.0941 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0045 | 0.0659 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Echinococcus multilocularis | thymidine kinase | 0.165 | 0.6632 | 1 |
Plasmodium falciparum | thymidylate kinase | 0.0142 | 0.0497 | 0.8237 |
Mycobacterium ulcerans | cytidine deaminase | 0.0055 | 0.0142 | 0.241 |
Trichomonas vaginalis | conserved hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0189 | 0.0625 |
Schistosoma mansoni | thymidylate kinase | 0.0142 | 0.0497 | 0.0749 |
Schistosoma mansoni | thyroid hormone receptor | 0.0147 | 0.0517 | 0.078 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0217 | 0.0802 | 0.6477 |
Schistosoma mansoni | hypothetical protein | 0.0107 | 0.0353 | 0.0533 |
Schistosoma mansoni | NADH-ubiquinone oxidoreductase | 0.008 | 0.0243 | 0.0366 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0325 | 0.1239 | 1 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.0022 | 0.0007 | 0.0022 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0038 | 0.0072 | 0.0108 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0283 | 0.0427 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0165 | 0.0588 | 1 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.014 | 0.0489 | 0.1617 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0038 | 0.0072 | 0.0238 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0189 | 0.0625 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.005 | 0.0121 | 0.0948 |
Brugia malayi | cytidine deaminase, identical | 0.0055 | 0.0142 | 0.1144 |
Echinococcus granulosus | glycogen phosphorylase | 0.0325 | 0.1239 | 0.1868 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0075 | 0.0224 | 0.074 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0038 | 0.0072 | 0.0108 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0038 | 0.0072 | 0.058 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0075 | 0.0224 | 0.074 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0325 | 0.1239 | 0.4095 |
Toxoplasma gondii | exonuclease III APE | 0.0038 | 0.0072 | 0.1124 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0022 | 0.0007 | 0.0022 |
Brugia malayi | thymidylate synthase | 0.0165 | 0.0588 | 0.4745 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0189 | 0.0625 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0165 | 0.0588 | 1 |
Entamoeba histolytica | Thymidylate kinase, putative | 0.0142 | 0.0497 | 0.1642 |
Trypanosoma cruzi | cytidine deaminase-like protein, putative | 0.0055 | 0.0142 | 0.0468 |
Echinococcus granulosus | NADH ubiquinone oxidoreductase 42 kDa subunit | 0.008 | 0.0243 | 0.0366 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.008 | 0.0243 | 0.0802 |
Trichomonas vaginalis | conserved hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0045 | 0.0068 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.005 | 0.0121 | 0.1399 |
Entamoeba histolytica | thymidine kinase, putative | 0.0763 | 0.3025 | 1 |
Echinococcus granulosus | cytidine deaminase | 0.0055 | 0.0142 | 0.0214 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0325 | 0.1239 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0052 | 0.0131 | 0.0433 |
Schistosoma mansoni | glycogen phosphorylase | 0.014 | 0.0489 | 0.0737 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0038 | 0.0072 | 0.1332 |
Echinococcus granulosus | thymidylate synthase | 0.0165 | 0.0588 | 0.0886 |
Mycobacterium ulcerans | thymidylate synthase | 0.0165 | 0.0588 | 1 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0165 | 0.0588 | 0.1943 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0027 | 0.0027 | 0.0088 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0118 | 0.0952 |
Toxoplasma gondii | thymidylate kinase | 0.0142 | 0.0497 | 0.8435 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0049 | 0.0395 |
Brugia malayi | RNase H family protein | 0.0022 | 0.0007 | 0.0053 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0189 | 0.0625 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0189 | 0.0625 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0038 | 0.0072 | 0.0238 |
Echinococcus granulosus | thymidine kinase | 0.165 | 0.6632 | 1 |
Echinococcus multilocularis | transfer RNA-Ile | 0.165 | 0.6632 | 1 |
Entamoeba histolytica | cytidine deaminase, putative | 0.0055 | 0.0142 | 0.0468 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.0283 | 0.2285 |
Giardia lamblia | Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative | 0.008 | 0.0243 | 0.0243 |
Schistosoma mansoni | phosphoglucomutase | 0.0022 | 0.0007 | 0.001 |
Trypanosoma brucei | ribonuclease H1 | 0.0022 | 0.0007 | 0.0022 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.014 | 0.0489 | 0.832 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0121 | 0.0975 |
Echinococcus multilocularis | cytidine deaminase | 0.0055 | 0.0142 | 0.0214 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.005 | 0.0121 | 0.0948 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0038 | 0.0072 | 0.0238 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.005 | 0.0121 | 0.1966 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0189 | 0.0625 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.005 | 0.0121 | 0.0399 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.008 | 0.0243 | 0.0802 |
Trichomonas vaginalis | conserved hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0027 | 0.0027 | 0.0088 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0165 | 0.0588 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0075 | 0.0224 | 0.0338 |
Brugia malayi | RNase H family protein | 0.0022 | 0.0007 | 0.0053 |
Brugia malayi | hypothetical protein | 0.0078 | 0.0237 | 0.191 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0022 | 0.0009 | 0.0013 |
Giardia lamblia | Glycogen phosphorylase | 0.0325 | 0.1239 | 0.1239 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0165 | 0.0588 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0325 | 0.1239 | 0.1868 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0075 | 0.0224 | 0.4432 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.008 | 0.0243 | 0.0802 |
Trichomonas vaginalis | conserved hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0045 | 0.0068 |
Brugia malayi | Inositol-1 | 0.0075 | 0.0224 | 0.1807 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0038 | 0.0072 | 0.0072 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0165 | 0.0588 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0189 | 0.0625 |
Giardia lamblia | Ribonuclease H | 0.0022 | 0.0007 | 0.0007 |
Echinococcus multilocularis | thymidylate synthase | 0.0165 | 0.0588 | 0.0886 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0325 | 0.1239 | 0.1868 |
Leishmania major | ribonuclease H1, putative | 0.0022 | 0.0007 | 0.0022 |
Echinococcus granulosus | geminin | 0.0174 | 0.0624 | 0.0941 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0189 | 0.0625 |
Toxoplasma gondii | cytidine and deoxycytidylate deaminase zinc-binding region domain-containing protein | 0.0055 | 0.0142 | 0.2325 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0038 | 0.0072 | 0.1332 |
Schistosoma mansoni | phosphoglucomutase | 0.0022 | 0.0007 | 0.001 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0038 | 0.0072 | 0.0238 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0075 | 0.0224 | 0.0338 |
Wolbachia endosymbiont of Brugia malayi | thymidylate kinase | 0.0142 | 0.0497 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0075 | 0.0224 | 0.074 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.008 | 0.0243 | 0.0802 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0325 | 0.1239 | 0.4095 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0189 | 0.0625 |
Loa Loa (eye worm) | inositol-1 | 0.0075 | 0.0224 | 0.1807 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0038 | 0.0072 | 0.0238 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0056 | 0.0145 | 0.048 |
Plasmodium vivax | thymidylate kinase, putative | 0.0142 | 0.0497 | 0.8325 |
Echinococcus multilocularis | solute carrier family 28 | 0.0352 | 0.135 | 0.2036 |
Leishmania major | thymidylate kinase-like protein | 0.0142 | 0.0497 | 0.1642 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0165 | 0.0588 | 0.1943 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0061 | 0.0166 | 0.0547 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0075 | 0.0224 | 0.074 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0045 | 0.0068 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0038 | 0.0072 | 0.0498 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.0624 | 0.0941 |
Treponema pallidum | thymidylate kinase (tmk) | 0.0142 | 0.0497 | 1 |
Onchocerca volvulus | 0.0031 | 0.0045 | 0.0311 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0078 | 0.0237 | 0.0782 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0283 | 0.0427 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0189 | 0.0625 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0078 | 0.0237 | 0.0782 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0165 | 0.0588 | 0.0886 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0189 | 0.0625 |
Trypanosoma brucei | thymidine kinase | 0.0763 | 0.3025 | 1 |
Giardia lamblia | Hypothetical protein | 0.008 | 0.0243 | 0.0243 |
Schistosoma mansoni | inositol monophosphatase | 0.0075 | 0.0224 | 0.0338 |
Onchocerca volvulus | 0.0055 | 0.0142 | 0.1096 | |
Echinococcus multilocularis | glycogen phosphorylase | 0.0325 | 0.1239 | 0.1868 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0118 | 0.0952 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0283 | 0.0427 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0142 | 0.0497 | 0.1642 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.014 | 0.0489 | 0.1617 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0283 | 0.0427 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0129 | 0.0443 | 0.0668 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0075 | 0.0224 | 0.3808 |
Brugia malayi | RNase H family protein | 0.0022 | 0.0007 | 0.0053 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0142 | 0.0497 | 0.1642 |
Echinococcus granulosus | concentrative Na nucleoside cotransporter | 0.0352 | 0.135 | 0.2036 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0022 | 0.0009 | 0.0013 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0067 | 0.0192 | 0.3263 |
Echinococcus multilocularis | concentrative Na+ nucleoside cotransporter | 0.0352 | 0.135 | 0.2036 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.004 | 0.0061 |
Schistosoma mansoni | hypothetical protein | 0.0218 | 0.0804 | 0.1212 |
Echinococcus multilocularis | ribonuclease H1 | 0.0022 | 0.0007 | 0.001 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0129 | 0.0443 | 0.0668 |
Mycobacterium ulcerans | thymidylate kinase | 0.0142 | 0.0497 | 0.8452 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0189 | 0.0625 |
Echinococcus multilocularis | thymidylate kinase | 0.0142 | 0.0497 | 0.0749 |
Giardia lamblia | Hypothetical protein | 0.008 | 0.0243 | 0.0243 |
Brugia malayi | Pre-SET motif family protein | 0.0217 | 0.0802 | 0.6477 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0118 | 0.0952 |
Leishmania major | cytidine deaminase-like protein | 0.0055 | 0.0142 | 0.0468 |
Echinococcus granulosus | thymidine kinase | 0.165 | 0.6632 | 1 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0056 | 0.0145 | 0.048 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0189 | 0.0625 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.0283 | 0.2285 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0142 | 0.0497 | 0.1642 |
Schistosoma mansoni | thyroid hormone receptor | 0.0147 | 0.0517 | 0.078 |
Trichomonas vaginalis | conserved hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0067 | 0.0192 | 0.1124 |
Trypanosoma cruzi | cytidine deaminase-like protein | 0.0055 | 0.0142 | 0.0468 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0078 | 0.0237 | 0.4026 |
Brugia malayi | carbohydrate phosphorylase | 0.0325 | 0.1239 | 1 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0075 | 0.0224 | 0.074 |
Trypanosoma brucei | unspecified product | 0.0027 | 0.0027 | 0.0088 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0325 | 0.1239 | 0.4095 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0075 | 0.0224 | 0.0338 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0022 | 0.0007 | 0.0022 |
Trichomonas vaginalis | cytidine deaminase, putative | 0.0055 | 0.0142 | 0.0468 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0763 | 0.3025 | 1 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0027 | 0.0027 | 0.0088 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0142 | 0.0497 | 0.1642 |
Schistosoma mansoni | hypothetical protein | 0.0129 | 0.0443 | 0.0668 |
Mycobacterium leprae | probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) | 0.0142 | 0.0497 | 0.7961 |
Schistosoma mansoni | phosphoglucomutase | 0.0022 | 0.0007 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0142 | 0.0497 | 0.0749 |
Giardia lamblia | Cytidine deaminase | 0.0055 | 0.0142 | 0.0142 |
Mycobacterium tuberculosis | Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase) | 0.0055 | 0.0142 | 0.241 |
Giardia lamblia | Thymidine kinase | 0.0763 | 0.3025 | 0.3025 |
Echinococcus granulosus | Thymidine kinase 2 mitochondrial | 0.165 | 0.6632 | 1 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0027 | 0.0027 | 0.0088 |
Echinococcus granulosus | solute carrier family 28 | 0.0352 | 0.135 | 0.2036 |
Loa Loa (eye worm) | deoxynucleoside kinase | 0.008 | 0.0243 | 0.1959 |
Leishmania major | hypothetical protein, conserved | 0.0056 | 0.0145 | 0.048 |
Brugia malayi | thymidylate kinase | 0.0142 | 0.0497 | 0.4011 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0055 | 0.0082 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0283 | 0.0427 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0075 | 0.0224 | 0.3739 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0009 | 0.0013 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0283 | 0.0427 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.005 | 0.0121 | 0.0399 |
Mycobacterium tuberculosis | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) | 0.0142 | 0.0497 | 0.8452 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0189 | 0.0625 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0325 | 0.1239 | 0.1868 |
Echinococcus granulosus | glycogen phosphorylase | 0.0325 | 0.1239 | 0.1868 |
Schistosoma mansoni | thymidylate kinase | 0.0142 | 0.0497 | 0.0749 |
Schistosoma mansoni | ap endonuclease | 0.0038 | 0.0072 | 0.0108 |
Trichomonas vaginalis | set domain proteins, putative | 0.0247 | 0.0925 | 0.3056 |
Echinococcus granulosus | Na+ dependent nucleoside transporter | 0.0352 | 0.135 | 0.2036 |
Echinococcus granulosus | ribonuclease H1 | 0.0022 | 0.0007 | 0.001 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0045 | 0.0068 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0055 | 0.0441 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0045 | 0.0068 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0142 | 0.0497 | 0.1642 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0325 | 0.1239 | 0.1868 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0142 | 0.0497 | 0.1642 |
Schistosoma mansoni | thymidine kinase | 0.165 | 0.6632 | 1 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0763 | 0.3025 | 1 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0763 | 0.3025 | 1 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0763 | 0.3025 | 1 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0763 | 0.3025 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0147 | 0.0517 | 0.078 |
Echinococcus multilocularis | NADH ubiquinone oxidoreductase 42 kDa subunit | 0.008 | 0.0243 | 0.0366 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0038 | 0.0072 | 0.0238 |
Echinococcus multilocularis | sodium:nucleoside cotransporter 2 | 0.023 | 0.0852 | 0.1285 |
Loa Loa (eye worm) | thymidylate synthase | 0.0165 | 0.0588 | 0.4745 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.0243 | 0.0802 |
Echinococcus multilocularis | thymidine kinase | 0.165 | 0.6632 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0118 | 0.0952 |
Leishmania major | thymidine kinase, putative | 0.0763 | 0.3025 | 1 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0038 | 0.0072 | 0.1223 |
Brugia malayi | hypothetical protein | 0.005 | 0.0121 | 0.0975 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0045 | 0.0362 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0189 | 0.0625 |
Trypanosoma brucei | RNA helicase, putative | 0.0218 | 0.0804 | 0.2656 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0075 | 0.0224 | 0.074 |
Loa Loa (eye worm) | thymidylate kinase | 0.0142 | 0.0497 | 0.4011 |
Onchocerca volvulus | 0.0247 | 0.0925 | 0.745 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0055 | 0.0441 |
Onchocerca volvulus | 0.0055 | 0.0142 | 0.1096 | |
Onchocerca volvulus | 0.0165 | 0.0588 | 0.4717 | |
Echinococcus granulosus | thymidylate kinase | 0.0142 | 0.0497 | 0.0749 |
Onchocerca volvulus | Putative thymidylate kinase | 0.0142 | 0.0497 | 0.3979 |
Echinococcus multilocularis | geminin | 0.0174 | 0.0624 | 0.0941 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0045 | 0.0068 |
Brugia malayi | Deoxynucleoside kinase family protein | 0.008 | 0.0243 | 0.1959 |
Schistosoma mansoni | glycogen phosphorylase | 0.0325 | 0.1239 | 0.1868 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 75 uM | Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay | ChEMBL. | 17194716 |
IC50 (binding) | = 75 uM | Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay | ChEMBL. | 17194716 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.