Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0034 | 0.0066 | 0.0764 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0041 | 0.0094 | 0.0875 |
Leishmania major | fructose-1,6-bisphosphate aldolase | 0.0088 | 0.0275 | 0.3039 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0041 | 0.0094 | 0.1331 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0041 | 0.0094 | 0.0875 |
Echinococcus multilocularis | fructose 1,6 bisphosphate aldolase | 0.0088 | 0.0275 | 0.426 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0041 | 0.0094 | 0.178 |
Loa Loa (eye worm) | succinate-CoA ligase | 0.0023 | 0.0028 | 0.0206 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0041 | 0.0094 | 0.0875 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0041 | 0.0094 | 0.0875 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0091 | 0.1046 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0068 | 0.0197 | 0.2992 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0068 | 0.0197 | 0.354 |
Brugia malayi | ecdysteroid receptor | 0.0041 | 0.0094 | 0.0875 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.0088 | 0.0275 | 0.2949 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0022 | 0.0021 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Onchocerca volvulus | 0.0064 | 0.0183 | 0.7911 | |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0228 | 0.2331 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0041 | 0.0094 | 0.0875 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.1046 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.1046 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0094 | 0.0913 |
Echinococcus granulosus | fructose 16 bisphosphate aldolase | 0.0088 | 0.0275 | 0.5694 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0032 | 0.0061 | 0.0527 |
Mycobacterium tuberculosis | 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) | 0.2646 | 1 | 1 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.0083 | 0.2253 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0041 | 0.0094 | 0.0875 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0041 | 0.0094 | 0.0875 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0041 | 0.0094 | 0.3807 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0042 | 0.0096 | 0.0746 |
Echinococcus granulosus | FTZ F1 alpha | 0.0041 | 0.0094 | 0.178 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0042 | 0.0096 | 0.1441 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0021 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0021 | 0.0094 |
Toxoplasma gondii | ATP-citrate lyase, putative | 0.0149 | 0.0506 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0036 | 0.0294 |
Schistosoma mansoni | thyroid hormone receptor | 0.0182 | 0.063 | 0.6576 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0022 | 0.0021 | 0.0191 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.0091 | 0.0063 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0183 | 0.1819 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0022 | 0.0021 | 0.0094 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0041 | 0.0094 | 0.0875 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0041 | 0.0094 | 0.0913 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.0752 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0017 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0094 | 0.0913 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0038 | 0.0556 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0122 | 0.1169 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0041 | 0.0094 | 0.0875 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0038 | 0.0273 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0032 | 0.0061 | 0.0527 |
Echinococcus multilocularis | fructose 1,6 bisphosphate aldolase | 0.0088 | 0.0275 | 0.426 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Brugia malayi | nuclear receptor RXR | 0.0022 | 0.0021 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0061 | 0.0566 |
Brugia malayi | nuclear receptor NHR-88 | 0.0041 | 0.0094 | 0.0875 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0064 | 0.0591 |
Toxoplasma gondii | fructose-1,6-bisphosphate aldolase | 0.0088 | 0.0275 | 0.5176 |
Mycobacterium ulcerans | glutaminase | 0.0266 | 0.0951 | 0.0926 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0041 | 0.0094 | 0.0875 |
Echinococcus multilocularis | jun protein | 0.0082 | 0.025 | 0.3848 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0022 | 0.0022 | 0.0144 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.1046 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.1046 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0041 | 0.0094 | 0.0913 |
Echinococcus multilocularis | fructose bisphosphate aldolase class I | 0.0088 | 0.0275 | 0.426 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0068 | 0.0197 | 0.017 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0224 | 0.079 | 0.8287 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0032 | 0.0061 | 0.0527 |
Schistosoma mansoni | carbonic anhydrase | 0.0032 | 0.0061 | 0.0527 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0038 | 0.0314 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0019 | 0.0012 | 0.0041 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0032 | 0.0061 | 0.0801 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0041 | 0.0094 | 0.178 |
Schistosoma mansoni | ATP-citrate synthase | 0.0131 | 0.0436 | 0.4518 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0068 | 0.0197 | 0.1968 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0122 | 0.1205 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0038 | 0.0416 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.0088 | 0.0275 | 0.2949 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0032 | 0.0061 | 0.0527 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Leishmania major | hypothetical protein, conserved | 0.0076 | 0.0228 | 0.2485 |
Echinococcus granulosus | fructose 16 bisphosphate aldolase | 0.0088 | 0.0275 | 0.5694 |
Onchocerca volvulus | 0.0026 | 0.0038 | 0.1189 | |
Schistosoma mansoni | thyroid hormone receptor | 0.0182 | 0.063 | 0.6576 |
Echinococcus multilocularis | Squalene phytoene synthase | 0.0076 | 0.0228 | 0.3497 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0041 | 0.0094 | 0.1331 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Brugia malayi | follicle stimulating hormone receptor | 0.0224 | 0.079 | 0.828 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Trypanosoma brucei | squalene synthase, putative | 0.0244 | 0.0867 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0122 | 0.1205 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0137 | 0.046 | 0.9706 |
Brugia malayi | glutaminase DH11.1 | 0.0266 | 0.0951 | 1 |
Trypanosoma cruzi | squalene synthase, putative | 0.0244 | 0.0867 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0038 | 0.0416 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0122 | 0.1169 |
Schistosoma mansoni | glutaminase | 0.0266 | 0.0951 | 1 |
Toxoplasma gondii | fructose-bisphosphate aldolase, putative | 0.0088 | 0.0275 | 0.5176 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.0088 | 0.0275 | 0.2949 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0041 | 0.0094 | 0.1331 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0032 | 0.0061 | 0.0566 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0228 | 0.2299 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0032 | 0.0061 | 0.0527 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0141 | 0.0475 | 0.7504 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0041 | 0.0094 | 0.0913 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.004 | 0.0091 | 0.0684 |
Echinococcus multilocularis | fructose 1,6 bisphosphate aldolase | 0.0088 | 0.0275 | 0.426 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0191 | 0.191 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0032 | 0.0061 | 0.0566 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0041 | 0.0094 | 0.0875 |
Schistosoma mansoni | succinyl-CoA synthetase-related | 0.0023 | 0.0028 | 0.0165 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0041 | 0.0094 | 0.0875 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0038 | 0.0314 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0038 | 0.0273 |
Echinococcus granulosus | fructose 16 bisphosphate aldolase | 0.0088 | 0.0275 | 0.5694 |
Schistosoma mansoni | hypothetical protein | 0.0141 | 0.0474 | 0.4919 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0021 | 0.0135 |
Echinococcus granulosus | succinyl coenzyme A synthetase alpha subunit | 0.0023 | 0.0028 | 0.0336 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0042 | 0.0096 | 0.1828 |
Schistosoma mansoni | jun-related protein | 0.0066 | 0.0191 | 0.191 |
Leishmania major | succinyl-CoA synthetase alpha subunit, putative | 0.0023 | 0.0028 | 0.0128 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0068 | 0.0197 | 0.017 |
Schistosoma mansoni | coup transcription factor | 0.0041 | 0.0094 | 0.0875 |
Leishmania major | succinyl-CoA synthetase alpha subunit, putative | 0.0023 | 0.0028 | 0.0128 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0094 | 0.0913 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.0083 | 1 |
Trypanosoma cruzi | squalene synthase, putative | 0.0244 | 0.0867 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0068 | 0.0197 | 0.1968 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0038 | 0.0314 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0041 | 0.0094 | 0.1331 |
Loa Loa (eye worm) | ATP-citrate synthase | 0.0149 | 0.0506 | 0.5278 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.1046 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0041 | 0.0094 | 0.0913 |
Leishmania major | squalene synthase, putative | 0.0244 | 0.0867 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.0266 | 0.0951 | 1 |
Trypanosoma brucei | succinyl-CoA synthetase alpha subunit, putative | 0.0023 | 0.0028 | 0.0318 |
Leishmania major | carbonic anhydrase-like protein | 0.0032 | 0.0061 | 0.0528 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0064 | 0.0552 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.0088 | 0.0275 | 0.2949 |
Brugia malayi | succinyl-CoA ligase [GDP-forming] alpha-chain, mitochindrial | 0.0023 | 0.0028 | 0.0165 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.1046 |
Brugia malayi | polk-prov protein | 0.003 | 0.0054 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0094 | 0.0913 |
Schistosoma mansoni | fructose 16-bisphosphate aldolase | 0.0088 | 0.0275 | 0.2801 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0032 | 0.0061 | 0.0527 |
Plasmodium falciparum | carbonic anhydrase | 0.0032 | 0.0061 | 0.1372 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0141 | 0.0474 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0041 | 0.0094 | 0.0875 |
Trypanosoma brucei | fructose-bisphosphate aldolase, glycosomal, putative | 0.0088 | 0.0275 | 0.3173 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0082 | 0.025 | 0.5144 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0041 | 0.0094 | 0.0875 |
Toxoplasma gondii | hypothetical protein | 0.0032 | 0.0061 | 0.071 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0141 | 0.0475 | 0.4935 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0054 | 0.0484 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0032 | 0.0061 | 0.0405 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0019 | 0.0012 | 0.0041 |
Onchocerca volvulus | 0.0026 | 0.0038 | 0.1189 | |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0182 | 0.063 | 1 |
Trypanosoma brucei | unspecified product | 0.0034 | 0.0066 | 0.0764 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0082 | 0.025 | 0.3848 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0064 | 0.0552 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0042 | 0.0096 | 0.0746 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0041 | 0.0094 | 0.0875 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0041 | 0.0094 | 0.178 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0041 | 0.0094 | 0.0913 |
Echinococcus granulosus | carbonic anhydrase II | 0.0032 | 0.0061 | 0.1071 |
Schistosoma mansoni | nuclear hormone receptor | 0.0041 | 0.0094 | 0.0875 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0141 | 0.0475 | 0.4935 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Chlamydia trachomatis | succinyl-CoA ligase subunit alpha | 0.0023 | 0.0028 | 0.5 |
Echinococcus granulosus | fructose bisphosphate aldolase class I | 0.0088 | 0.0275 | 0.5694 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0041 | 0.0094 | 0.0875 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.0083 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0021 | 0.0094 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0032 | 0.0061 | 0.0527 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.003 | 0.0054 | 0.062 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.0752 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0041 | 0.0094 | 0.0875 |
Echinococcus granulosus | Squalene phytoene synthase | 0.0076 | 0.0228 | 0.4675 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0041 | 0.0094 | 0.178 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0041 | 0.0094 | 0.0875 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0032 | 0.0061 | 0.0527 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0041 | 0.0094 | 0.0875 |
Echinococcus granulosus | dna polymerase kappa | 0.004 | 0.0091 | 0.1703 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0032 | 0.0061 | 0.0527 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0041 | 0.0094 | 0.178 |
Onchocerca volvulus | 0.0041 | 0.0094 | 0.3807 | |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0038 | 0.0273 |
Trypanosoma cruzi | phytoene synthase, putative | 0.0076 | 0.0228 | 0.2388 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.1046 |
Mycobacterium tuberculosis | Probable phytoene synthase PhyA | 0.0076 | 0.0228 | 0.0212 |
Mycobacterium ulcerans | 3-dehydroquinate dehydratase | 0.2646 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0072 | 0.0637 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0068 | 0.0197 | 0.2119 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0041 | 0.0094 | 0.0875 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0041 | 0.0094 | 0.0875 |
Brugia malayi | fructose-bisphosphate aldolase 1 | 0.0088 | 0.0275 | 0.2801 |
Schistosoma mansoni | lamin | 0.0026 | 0.0038 | 0.0273 |
Toxoplasma gondii | fructose-1,6-bisphosphate aldolase | 0.0088 | 0.0275 | 0.5176 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0094 | 0.0913 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0042 | 0.0096 | 0.1441 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0041 | 0.0094 | 0.3807 |
Brugia malayi | fructose-bisphosphate aldolase 2 | 0.0088 | 0.0275 | 0.2801 |
Echinococcus granulosus | carbonic anhydrase | 0.0032 | 0.0061 | 0.1071 |
Loa Loa (eye worm) | DR-78 | 0.0019 | 0.0012 | 0.0041 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0041 | 0.0094 | 0.178 |
Echinococcus multilocularis | carbonic anhydrase | 0.0032 | 0.0061 | 0.0801 |
Echinococcus granulosus | lamin | 0.0026 | 0.0038 | 0.0556 |
Schistosoma mansoni | fructose 16-bisphosphate aldolase | 0.0088 | 0.0275 | 0.2801 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0072 | 0.0637 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0019 | 0.0012 | 0.0041 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0072 | 0.0637 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.1046 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0032 | 0.0061 | 0.0527 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.0091 | 0.0063 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0041 | 0.0094 | 0.1331 |
Echinococcus granulosus | carbonic anhydrase | 0.0032 | 0.0061 | 0.1071 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0042 | 0.0096 | 0.2785 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0041 | 0.0094 | 0.0913 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0041 | 0.0094 | 0.0875 |
Echinococcus multilocularis | carbonic anhydrase | 0.0032 | 0.0061 | 0.0801 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0094 | 0.0913 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0032 | 0.0061 | 0.0709 |
Mycobacterium tuberculosis | Probable succinyl-CoA synthetase (alpha chain) SucD (SCS-alpha) | 0.0023 | 0.0028 | 0.0011 |
Plasmodium vivax | fructose 1,6-bisphosphate aldolase, putative | 0.0088 | 0.0275 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0072 | 0.0969 |
Echinococcus multilocularis | dna polymerase kappa | 0.004 | 0.0091 | 0.1274 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.1046 |
Echinococcus granulosus | jun protein | 0.0082 | 0.025 | 0.5144 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0068 | 0.0197 | 0.017 |
Brugia malayi | ATP-citrate synthase | 0.0149 | 0.0506 | 0.5258 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.0752 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0068 | 0.0197 | 0.4001 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0091 | 0.1046 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0094 | 0.0913 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.003 | 0.0054 | 0.062 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0141 | 0.0474 | 0.748 |
Schistosoma mansoni | lamin | 0.0026 | 0.0038 | 0.0273 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0041 | 0.0094 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0061 | 0.0566 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0041 | 0.0094 | 0.1331 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0041 | 0.0094 | 0.1331 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0041 | 0.0094 | 0.0875 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0241 | 0.2471 |
Loa Loa (eye worm) | fructose-bisphosphate aldolase 1 | 0.0088 | 0.0275 | 0.2831 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0021 | 0.0135 |
Onchocerca volvulus | 0.0023 | 0.0028 | 0.0719 | |
Brugia malayi | bZIP transcription factor family protein | 0.0082 | 0.025 | 0.253 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0021 | 0.0094 |
Plasmodium falciparum | fructose-bisphosphate aldolase | 0.0088 | 0.0275 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0021 | 0.0135 |
Loa Loa (eye worm) | fructose-bisphosphate aldolase 2 | 0.0088 | 0.0275 | 0.2831 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0041 | 0.0094 | 0.0875 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0032 | 0.0061 | 0.0527 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.004 | 0.0091 | 0.0684 |
Echinococcus multilocularis | carbonic anhydrase | 0.0032 | 0.0061 | 0.0801 |
Echinococcus granulosus | carbonic anhydrase | 0.0032 | 0.0061 | 0.1071 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0072 | 0.1295 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0032 | 0.0061 | 0.0405 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0022 | 0.0021 | 0.0135 |
Loa Loa (eye worm) | acetyltransferase | 0.0141 | 0.0475 | 0.4956 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0041 | 0.0094 | 0.3807 |
Mycobacterium ulcerans | phytoene synthase, CrtB | 0.0076 | 0.0228 | 0.0201 |
Brugia malayi | nuclear hormone receptor | 0.0041 | 0.0094 | 0.0875 |
Brugia malayi | steroid hormone receptor | 0.0041 | 0.0094 | 0.0875 |
Echinococcus multilocularis | succinyl coenzyme A synthetase alpha subunit | 0.0023 | 0.0028 | 0.0251 |
Wolbachia endosymbiont of Brugia malayi | succinyl-CoA synthetase, alpha subunit | 0.0023 | 0.0028 | 0.5 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0032 | 0.0061 | 0.0527 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0021 | 0.0094 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0041 | 0.0094 | 0.1331 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0041 | 0.0094 | 0.178 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0091 | 0.0752 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0094 | 0.0913 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0038 | 0.0416 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0068 | 0.0197 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0021 | 0.0135 |
Onchocerca volvulus | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog | 0.0076 | 0.0228 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0061 | 0.0566 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0038 | 0.0556 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.0022 | 0.0103 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0022 | 0.0021 | 0.0094 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0041 | 0.0094 | 0.0913 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0032 | 0.0061 | 0.0566 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0041 | 0.0094 | 0.0875 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0041 | 0.0094 | 0.178 |
Trichomonas vaginalis | glutaminase, putative | 0.0266 | 0.0951 | 1 |
Loa Loa (eye worm) | glutaminase | 0.0266 | 0.0951 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0061 | 0.0527 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (ADMET) | = 129.8 uM | Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay | ChEMBL. | 18304818 |
MIC (functional) | = 0.39 uM | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis by agar dilution method | ChEMBL. | 18304818 |
MIC (functional) | = 0.39 uM | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis by agar dilution method | ChEMBL. | 18304818 |
MIC (functional) | = 1.62 uM | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv by agar dilution method | ChEMBL. | 18304818 |
MIC (functional) | = 1.62 uM | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv by agar dilution method | ChEMBL. | 18304818 |
MIC (functional) | = 103.85 uM | Antimycobacterial activity against Mycobacterium smegmatis MC2 by agar dilution method | ChEMBL. | 18304818 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.