Detailed information for compound 514028

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 426.204 | Formula: C17H11Cl2F2N5O2
  • H donors: 2 H acceptors: 4 LogP: 3.94 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC(=O)c1cc(F)cc(c1NC(=O)c1cc(nn1c1ncccc1Cl)F)Cl
  • InChi: 1S/C17H11Cl2F2N5O2/c1-22-16(27)9-5-8(20)6-11(19)14(9)24-17(28)12-7-13(21)25-26(12)15-10(18)3-2-4-23-15/h2-7H,1H3,(H,22,27)(H,24,28)
  • InChiKey: GKHIVGMWLNWAMK-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0058 0.0161 0.0311
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0156 0.0455
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0018 0.0054
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.002 0.0019 0.0036
Schistosoma mansoni carbonyl reductase 0.002 0.0019 0.0036
Plasmodium vivax thioredoxin reductase, putative 0.0933 0.3424 1
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0078 0.0078
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0077 0.0234 0.0847
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0028 0.0082
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0046 0.0046
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0184 0.0631 0.1214
Onchocerca volvulus 0.0159 0.0539 0.2966
Brugia malayi Retinol dehydrogenase 12 0.002 0.0019 0.0055
Echinococcus multilocularis musashi 0.0056 0.0156 0.03
Leishmania major NADH dehydrogenase, putative 0.0197 0.0679 0.0679
Trichomonas vaginalis steroid dehydrogenase, putative 0.002 0.0019 0.0052
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0056 0.0192
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0741 0.2708 0.7905
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0191 0.0367
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.002 0.0019 0.0036
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0192 0.0561
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0197 0.0679 0.1931
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0019 0.0036
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0104 0.0333 0.0333
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0005 0.0005
Schistosoma mansoni steroid dehydrogenase 0.002 0.0019 0.0036
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0019 0.0053
Schistosoma mansoni steroid dehydrogenase 0.002 0.0019 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0151 0.029
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0028 0.0054
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0122 0.0122
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0019 0.0069
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0168 0.0323
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0018 0.0051
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0069 0.0203 0.0579
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0176 0.0338
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0168 0.0323
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0959 0.3532
Echinococcus granulosus dro:myosuppressin receptor 0.0055 0.0151 0.029
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0047 0.009
Brugia malayi hypothetical protein 0.0055 0.0151 0.044
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0046 0.0135
Loa Loa (eye worm) norepinephrine transporter 0.0159 0.0539 0.1573
Echinococcus multilocularis retinol dehydrogenase 13 0.002 0.0019 0.0036
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0046 0.0131
Mycobacterium ulcerans carboxylesterase, LipT 0.0058 0.0161 0.0596
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0019 0.0019
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0078 0.0225
Brugia malayi hypothetical protein 0.002 0.0019 0.0055
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0104 0.0333 0.0333
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0168 0.0323
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0078 0.0215
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0019 0.0019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.0151 0.029
Echinococcus granulosus 7TM GPCR rhodopsin 0.0055 0.0151 0.029
Echinococcus multilocularis sodium and chloride dependent glycine 0.0027 0.0046 0.0089
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0011 0.0021
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0005 0.0009
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0046 0.0089
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0019 0.0019
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0741 0.2708 0.5209
Echinococcus granulosus aryl hydrocarbon receptor 0.0026 0.0042 0.0081
Brugia malayi Carboxylesterase family protein 0.0343 0.1224 0.3574
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0122 0.0434
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0197 0.0679 0.1982
Echinococcus multilocularis survival motor neuron protein 1 0.0483 0.1745 0.3358
Brugia malayi Pre-SET motif family protein 0.0062 0.0176 0.0513
Loa Loa (eye worm) doublecortin family protein 0.012 0.0394 0.115
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0356 0.1301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0041 0.0134
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.0151 0.029
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0019 0.0019
Loa Loa (eye worm) melatonin receptor type 1A 0.0055 0.0151 0.044
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0005 0.0005
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0197 0.0679 0.1306
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0055
Schistosoma mansoni hypothetical protein 0.0054 0.0149 0.0286
Loa Loa (eye worm) oxidoreductase 0.002 0.0019 0.0055
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0078 0.0229
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0055 0.0151 0.029
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0192 0.0192
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0168 0.049
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2266 0.8396 0.8396
Brugia malayi hypothetical protein 0.0017 0.0009 0.0027
Brugia malayi glutamate synthase 0.0197 0.0679 0.1982
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0055 0.0151 0.029
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0019 0.0053
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Echinococcus multilocularis acetylcholinesterase 0.0343 0.1224 0.2354
Brugia malayi Dehydrogenases, short chain protein 30 0.002 0.0019 0.0055
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0197 0.0679 0.2494
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.026 0.0914 0.1759
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.0151 0.029
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.0356 0.1257
Onchocerca volvulus 0.0055 0.0151 0.0753
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0019 0.0053
Schistosoma mansoni chromobox protein 0.0071 0.0209 0.0402
Schistosoma mansoni neuropeptide receptor 0.0055 0.0151 0.029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0151 0.029
Schistosoma mansoni jun-related protein 0.0211 0.0733 0.141
Treponema pallidum NADH oxidase 0.0741 0.2708 1
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.002 0.0019 0.0052
Onchocerca volvulus 0.012 0.0394 0.2139
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0197 0.0679 0.1306
Loa Loa (eye worm) glutathione reductase 0.0933 0.3424 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Loa Loa (eye worm) hypothetical protein 0.0058 0.0161 0.0471
Trypanosoma brucei trypanothione reductase 0.0933 0.3424 0.3424
Echinococcus multilocularis serotonin transporter 0.0159 0.0539 0.1037
Schistosoma mansoni hypothetical protein 0.0055 0.0151 0.029
Brugia malayi Serotonin receptor 0.0055 0.0151 0.044
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.002 0.0019 0.0069
Loa Loa (eye worm) hypothetical protein 0.0335 0.1195 0.349
Loa Loa (eye worm) oxidoreductase 0.002 0.0019 0.0055
Onchocerca volvulus 0.0027 0.0046 0.0157
Plasmodium falciparum amino acid transporter, putative 0.0027 0.0046 0.0121
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0197 0.0679 0.2455
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0019 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0055
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0192 0.0369
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0005 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0151 0.029
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0197 0.0679 0.2506
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0191 0.0367
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0078 0.0078
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0197 0.0679 0.2494
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0019 0.0019
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0049 0.013 0.0249
Schistosoma mansoni loxhd1 0.012 0.0394 0.0758
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0413 0.1486 0.4228
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0175 0.0646
Loa Loa (eye worm) hypothetical protein 0.0197 0.0679 0.1982
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0078 0.0078
Entamoeba histolytica disulphide oxidoreductase, putative 0.0197 0.0679 1
Loa Loa (eye worm) inositol-1 0.0077 0.0234 0.0682
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Echinococcus granulosus allatostatin A receptor 0.0055 0.0151 0.029
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0019 0.0015 0.0029
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.002 0.0019 0.0052
Trichomonas vaginalis glutamate synthase, putative 0.0197 0.0679 0.2494
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0028 0.0054
Brugia malayi hypothetical protein 0.012 0.0394 0.115
Loa Loa (eye worm) oxidoreductase 0.002 0.0019 0.0055
Loa Loa (eye worm) oxidoreductase 0.002 0.0019 0.0055
Leishmania major hypothetical protein, conserved 0.0036 0.0078 0.0078
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0333 0.1216
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0019 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0041 0.0133
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0019 0.0053
Trichomonas vaginalis glutamate synthase, putative 0.0197 0.0679 0.2494
Leishmania major oxidoreductase-like protein 0.002 0.0019 0.0019
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0005 0.0009
Onchocerca volvulus 0.0055 0.0151 0.0753
Echinococcus multilocularis chromobox protein 1 0.0071 0.0209 0.0402
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0044 0.0044
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0055 0.0151 0.029
Leishmania major ATP-dependent phosphofructokinase 0.011 0.0356 0.0356
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0197 0.0679 0.1306
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0197 0.0679 0.0679
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1978 0.7322 0.7322
Schistosoma mansoni lamin 0.0056 0.0156 0.03
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0015 0.0029
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0056 0.0161
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0197 0.0679 0.1971
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.002 0.0019 0.0019
Brugia malayi bZIP transcription factor family protein 0.026 0.0914 0.267
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0741 0.2708 0.7703
Echinococcus multilocularis lamin dm0 0.0056 0.0156 0.03
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.002 0.0019 0.0053
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0741 0.2708 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0055
Schistosoma mansoni steroid dehydrogenase 0.002 0.0019 0.0036
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0042 0.0042
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0018 0.0035
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0356 0.1301
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0959 0.3532
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0019 0.0053
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0055 0.0151 0.029
Onchocerca volvulus 0.0055 0.0151 0.0753
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0197 0.0679 1
Brugia malayi G protein-coupled receptor 0.0055 0.0151 0.044
Giardia lamblia GTOR 0.0047 0.0122 0.0385
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0388 0.1391 0.4063
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0191 0.0558
Echinococcus multilocularis lipoxygenase domain containing protein 0.012 0.0394 0.0758
Toxoplasma gondii selenide, water dikinase 0.0197 0.0679 0.1982
Schistosoma mansoni acetylcholinesterase 0.0058 0.0161 0.0311
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0019 0.0019
Onchocerca volvulus 0.0055 0.0151 0.0753
Brugia malayi jmjC domain containing protein 0.0016 0.0005 0.0014
Schistosoma mansoni sulfide quinone reductase 0.0197 0.0679 0.1306
Trypanosoma cruzi trypanothione reductase, putative 0.0933 0.3424 0.3424
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0055 0.0151 0.029
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.0151 0.029
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0019 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0077 0.0267
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0019 0.0053
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0019 0.0069
Brugia malayi Serotonin receptor 0.0539 0.1957 0.5715
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0044 0.0126
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0047 0.009
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0005 0.0014
Leishmania major short chain dehydrogenase, putative 0.002 0.0019 0.0019
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0019 0.0019
Plasmodium vivax JmjC domain containing protein 0.0016 0.0005 0.001
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0104 0.0369
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0056 0.0165
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Echinococcus multilocularis neuropeptide receptor A26 0.0055 0.0151 0.029
Trichomonas vaginalis adenylate cyclase, putative 0.0026 0.0042 0.0139
Loa Loa (eye worm) dehydrogenase 0.002 0.0019 0.0055
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0055
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.0151 0.044
Schistosoma mansoni glutamate synthase 0.0197 0.0679 0.1306
Schistosoma mansoni steroid dehydrogenase 0.002 0.0019 0.0036
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0197 0.0679 0.1931
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0055 0.0151 0.044
Brugia malayi hypothetical protein 0.0055 0.0151 0.044
Brugia malayi glutathione reductase 0.0933 0.3424 1
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.002 0.0019 0.0053
Loa Loa (eye worm) carboxylesterase 0.0058 0.0161 0.0471
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0027 0.0046 0.0089
Brugia malayi follicle stimulating hormone receptor 0.0055 0.0151 0.044
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Echinococcus multilocularis glutamate synthase 0.0197 0.0679 0.1306
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0042 0.0139
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0078 0.0229
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0015 0.0029
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Entamoeba histolytica thioredoxin reductase, putative 0.0197 0.0679 1
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0356 0.512
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0356 0.1301
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2266 0.8396 0.8396
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0356 0.0356
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0018 0.0035
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0197 0.0679 0.2494
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0078 0.0078
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0028 0.0054
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0019 0.0019
Brugia malayi TAR-binding protein 0.0066 0.0191 0.0558
Echinococcus granulosus glutamate synthase 0.0197 0.0679 0.1306
Brugia malayi hypothetical protein 0.012 0.0394 0.115
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.0151 0.029
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0104 0.0369
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0019 0.0069
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0197 0.0679 1
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0197 0.0679 0.1979
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0135
Echinococcus multilocularis sodium channel protein 0.0124 0.0409 0.0787
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0135
Brugia malayi oxidoreductase 0.002 0.0019 0.0055
Loa Loa (eye worm) hypothetical protein 0.0343 0.1224 0.3574
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0055 0.0151 0.044
Schistosoma mansoni ap endonuclease 0.002 0.0018 0.0035
Mycobacterium ulcerans dehydrogenase 0.002 0.0019 0.0069
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Treponema pallidum oxidoreductase 0.0197 0.0679 0.2455
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.03
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0019 0.0005
Loa Loa (eye worm) phosphofructokinase 0.011 0.0356 0.1041
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0197 0.0679 0.1971
Onchocerca volvulus 0.0055 0.0151 0.0753
Onchocerca volvulus Netrin receptor homolog 0.003 0.0058 0.0222
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0197 0.0679 1
Echinococcus multilocularis Ankyrin 0.003 0.0059 0.0113
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0168 0.0323
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0018 0.0018
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0124 0.0409 0.0409
Brugia malayi Augmenter of liver regeneration 0.0036 0.0078 0.0229
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0333 0.1216
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0135
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0197 0.0679 0.2506
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0005 0.0005
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.0151 0.029
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0019 0.0053
Leishmania major hypothetical protein, conserved 0.0197 0.0679 0.0679
Schistosoma mansoni opsin-like receptor 0.0055 0.0151 0.029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0151 0.029
Brugia malayi dehydrogenases, short chain protein 9 0.002 0.0019 0.0055
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0046 0.0046
Trypanosoma brucei C-8 sterol isomerase, putative 0.0388 0.1391 0.1391
Trichomonas vaginalis spcc417.12 protein, putative 0.0058 0.0161 0.058
Entamoeba histolytica hypothetical protein 0.0037 0.0085 0.1008
Leishmania major pteridine reductase 1 0.002 0.0019 0.0019
Schistosoma mansoni growth hormone secretagogue receptor 0.0055 0.0151 0.029
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0959 0.3532
Schistosoma mansoni lamin 0.0056 0.0156 0.03
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.002 0.0019 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0143 0.0275
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Giardia lamblia Short-chain dehydrogenase, putative 0.002 0.0019 0.0001
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0192 0.0369
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.003 0.0059 0.0113
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0056 0.0142
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0046 0.0135
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0027 0.0046 0.0089
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0197 0.0679 0.1306
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0079 0.0275
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0019 0.0036
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0197 0.0679 0.1306
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0019 0.0036
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0104 0.0489
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0046 0.0046
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0019 0.0019
Echinococcus granulosus microtubule associated protein 2 0.1408 0.5198 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0104 0.0333 0.0333
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0058 0.0161 0.0311
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0018 0.0018
Echinococcus granulosus lipoxygenase domain containing protein 0.012 0.0394 0.0758
Plasmodium vivax ferrodoxin reductase, putative 0.0197 0.0679 0.1979
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0019 0.0019
Plasmodium falciparum thioredoxin reductase 0.0933 0.3424 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0197 0.0679 0.1982
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0055 0.0151 0.029
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.002 0.0019 0.0053
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0197 0.0679 0.2494
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0019 0.0005
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0019 0.0019
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0191 0.0367
Echinococcus granulosus hypothetical protein 0.002 0.0019 0.0036
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0197 0.0679 0.2506
Schistosoma mansoni sodium/chloride dependent transporter 0.0028 0.005 0.0096
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0018 0.0018
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0019 0.0019
Onchocerca volvulus 0.049 0.1772 1
Echinococcus granulosus g protein coupled receptor 0.0055 0.0151 0.029
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0077 0.0234 0.0234
Schistosoma mansoni sulfide quinone reductase 0.0197 0.0679 0.1306
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0015 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0019 0.0019
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0197 0.0679 0.2506
Echinococcus granulosus phd:f box containing protein 0.0016 0.0005 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.005 0.0167
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0019 0.0015 0.0029
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0413 0.1486 0.4228
Loa Loa (eye worm) hypothetical protein 0.0183 0.0629 0.1837
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.002 0.0019 0.0069
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0413 0.1486 0.4228
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.002 0.0019 0.0053
Schistosoma mansoni glutamate synthase 0.0197 0.0679 0.1306
Onchocerca volvulus 0.0074 0.0221 0.1155
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0009 0.0018
Plasmodium falciparum thioredoxin reductase 0.0741 0.2708 0.7905
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0055 0.0151 0.029
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0343 0.1224 0.2354
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Brugia malayi Uncoordinated protein 44 0.003 0.0058 0.0168
Schistosoma mansoni hypothetical protein 0.0098 0.0313 0.0601
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0062 0.0176 0.0513
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.005 0.0167
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0544 0.1975 0.5767
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0135
Schistosoma mansoni opsin-like receptor 0.0055 0.0151 0.029
Brugia malayi Protein kinase domain containing protein 0.0031 0.0061 0.0179
Echinococcus granulosus neuropeptide s receptor 0.0055 0.0151 0.029
Onchocerca volvulus 0.0056 0.0156 0.0783
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0197 0.0679 0.1931
Schistosoma mansoni survival motor neuron protein 0.0098 0.0313 0.0601
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0151 0.029
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0197 0.0679 0.1931
Schistosoma mansoni neuropeptide receptor 0.0055 0.0151 0.029
Loa Loa (eye worm) hepatopoietin HPO2 0.0036 0.0078 0.0229
Brugia malayi PAS domain containing protein 0.01 0.0318 0.0929
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0175 0.0337
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0333 0.0641
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0019 0.0019
Plasmodium falciparum glutathione reductase 0.0741 0.2708 0.7905
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0027 0.0044 0.013
Echinococcus granulosus 7tm_1 domain containing protein 0.0055 0.0151 0.029
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0356 0.1041
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0741 0.2708 0.7907
Trypanosoma cruzi hypothetical protein, conserved 0.0197 0.0679 0.0679
Onchocerca volvulus 0.0055 0.0151 0.0753
Loa Loa (eye worm) hypothetical protein 0.0159 0.0539 0.1573
Schistosoma mansoni hypothetical protein 0.0197 0.0679 0.1306
Trypanosoma brucei hypothetical protein, conserved 0.0197 0.0679 0.0679
Onchocerca volvulus 0.0027 0.0046 0.0157
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0055
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0005 0.0014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Echinococcus granulosus chromobox protein 1 0.0071 0.0209 0.0402
Echinococcus multilocularis orexin receptor type 2 0.0055 0.0151 0.029
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0019 0.0036
Brugia malayi Dopamine receptor protein 1 0.0055 0.0151 0.044
Mycobacterium ulcerans ferredoxin reductase 0.0197 0.0679 0.2506
Mycobacterium ulcerans monoxygenase 0.0197 0.0679 0.2506
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0036 0.0078 0.0151
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0015 0.0038
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.002 0.0019 0.0019
Echinococcus multilocularis g protein coupled receptor 0.0055 0.0151 0.029
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0122 0.1568
Schistosoma mansoni hypothetical protein 0.0055 0.0151 0.029
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0413 0.1486 0.4228
Echinococcus multilocularis geminin 0.0176 0.0602 0.1159
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0176 0.0513
Loa Loa (eye worm) oxidoreductase 0.002 0.0019 0.0055
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0192 0.0561
Mycobacterium ulcerans dehydrogenase/reductase 0.002 0.0019 0.0069
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0191 0.0367
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.006 0.0205
Mycobacterium ulcerans hypothetical protein 0.0197 0.0679 0.2506
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0197 0.0679 1
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0333 0.1216
Brugia malayi hypothetical protein 0.0055 0.0151 0.044
Leishmania major hypothetical protein, conserved 0.002 0.0019 0.0019
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0015 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0058 0.0168
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0027 0.0046 0.0089
Echinococcus multilocularis G-protein coupled receptor, putative 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0159 0.0539 0.1573
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0005 0.0009
Echinococcus multilocularis para nitrobenzyl esterase 0.0058 0.0161 0.0311
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0073 0.0219 0.0421
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0046 0.0135
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0122 0.0122
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0058 0.0161 0.0459
Loa Loa (eye worm) hypothetical protein 0.0055 0.0152 0.0444
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0069 0.0203 0.0579
Echinococcus granulosus tachykinin peptides receptor 99D 0.0055 0.0151 0.029
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.0151 0.029
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0019 0.0052
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0055 0.0151 0.044
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0056 0.0151
Loa Loa (eye worm) hypothetical protein 0.0322 0.1145 0.3343
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0019 0.0069
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.002 0.0019 0.0053
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0356 0.512
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0028 0.0054
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.002 0.0019 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1978 0.7322 0.7322
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Brugia malayi hypothetical protein 0.0055 0.0151 0.044
Brugia malayi Dopamine receptor 0.0055 0.0151 0.044
Toxoplasma gondii thioredoxin reductase 0.0933 0.3424 1
Loa Loa (eye worm) hypothetical protein 0.012 0.0394 0.115
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0077 0.0234 0.326
Schistosoma mansoni aryl hydrocarbon receptor 0.01 0.0318 0.0612
Echinococcus granulosus alpha 1A adrenergic receptor 0.0055 0.0151 0.029
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0096 0.0338
Trichomonas vaginalis inositol monophosphatase, putative 0.0077 0.0234 0.0847
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0086 0.0086
Mycobacterium tuberculosis Probable dehydrogenase 0.0413 0.1486 0.4228
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.043 0.155 0.4525
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.0151 0.044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0077 0.0267
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0042 0.0139
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0055 0.0151 0.029
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0018 0.0054
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0046 0.0135
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0175 0.0646
Mycobacterium leprae Possible regulatory protein 0.0026 0.0042 0.012
Schistosoma mansoni rab6-interacting 0.012 0.0394 0.0758
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0175 0.0337
Brugia malayi hypothetical protein 0.0055 0.0151 0.044
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0055
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0055 0.0151 0.029
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0159 0.0539 0.1037
Echinococcus granulosus jun protein 0.026 0.0914 0.1759
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0044 0.0044
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0015 0.0029
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0356 0.512
Onchocerca volvulus 0.0055 0.0151 0.0753
Brugia malayi GnHR receptor homolog 0.0055 0.0151 0.044
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0019 0.0019
Brugia malayi G protein-coupled receptor F59B2.13 0.0055 0.0151 0.044
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0151 0.029
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0077 0.0234 0.0801
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0197 0.0679 0.1982
Plasmodium vivax steroid dehydrogenase, putative 0.002 0.0019 0.005
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0156 0.0455
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0176 0.0338
Brugia malayi putative neuropeptide receptor 0.0055 0.0151 0.044
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0192 0.0192
Schistosoma mansoni myosin xvIII 0.0055 0.0151 0.029
Leishmania major 3-keto-dihydrosphingosine reductase 0.002 0.0019 0.0019
Echinococcus granulosus biogenic amine 5HT receptor 0.0055 0.0151 0.029
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0088 0.017
Loa Loa (eye worm) oxidoreductase 0.002 0.0019 0.0055
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0463 0.1672 0.3217
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0019 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0041 0.0133
Echinococcus multilocularis inositol monophosphatase 1 0.0077 0.0234 0.045
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0086 0.0086
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0741 0.2708 1
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0197 0.0679 0.0679
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0055 0.0151 0.029
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0741 0.2708 1
Loa Loa (eye worm) oxidoreductase 0.002 0.0019 0.0055
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.002 0.0019 0.0053
Echinococcus granulosus carbonyl reductase 1 0.002 0.0019 0.0036
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0211 0.0733 0.141
Loa Loa (eye worm) hypothetical protein 0.0044 0.0111 0.0323
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0046 0.0089
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0056 0.0142
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0156 0.0455
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0184 0.0631 0.233
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.0137
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0019 0.0052
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0019 0.0069
Toxoplasma gondii exonuclease III APE 0.002 0.0018 0.0054
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0168 0.0323
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Brugia malayi hypothetical protein 0.0058 0.0161 0.0471
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0056 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0093 0.0327
Loa Loa (eye worm) hypothetical protein 0.0022 0.0028 0.0082
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.0151 0.029
Schistosoma mansoni ap endonuclease 0.002 0.0018 0.0035
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0018 0.005
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0197 0.0679 0.2494
Loa Loa (eye worm) hypothetical protein 0.0159 0.0539 0.1573
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0042 0.0139
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0019 0.0069
Echinococcus multilocularis netrin receptor unc 5 0.003 0.0058 0.0111
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.003 0.0058 0.0111
Brugia malayi jmjC domain containing protein 0.0016 0.0005 0.0014
Echinococcus granulosus sodium and chloride dependent glycine 0.0027 0.0046 0.0089
Echinococcus granulosus geminin 0.0176 0.0602 0.1159
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0124 0.0409 0.0787
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0019 0.0019
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.002 0.0019 0.0055
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0005 0.0005
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0197 0.0679 0.1306
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Mycobacterium ulcerans oxidoreductase 0.002 0.0019 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0077 0.0267
Loa Loa (eye worm) hypothetical protein 0.0026 0.0043 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.03
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0209 0.0756
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0176 0.0338
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0122 0.0235
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0029 0.0029
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0058 0.0161 0.0311
Trichomonas vaginalis set domain proteins, putative 0.049 0.1771 0.6535
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0055 0.0151 0.044
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0197 0.0679 0.2494
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0164 0.0558 0.1629
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0028 0.0087
Echinococcus granulosus fmrfamide receptor 0.0055 0.0151 0.029
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0055 0.0151 0.029
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0197 0.0679 0.1982
Echinococcus multilocularis Polycystic kidney disease protein 0.012 0.0394 0.0758
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0356 0.0686
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.0168
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0077 0.0234 0.0847
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0005 0.0014
Onchocerca volvulus 0.0027 0.0046 0.0157
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2696 1 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0077 0.0234 0.0234
Onchocerca volvulus 0.0058 0.0161 0.0814
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.0151 0.029
Schistosoma mansoni polycystin 1-related 0.012 0.0394 0.0758
Schistosoma mansoni hypothetical protein 0.0037 0.0085 0.0163
Loa Loa (eye worm) hypothetical protein 0.0491 0.1776 0.5188
Leishmania major hypothetical protein, conserved 0.002 0.0019 0.0019
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0192 0.263
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0197 0.0679 0.1931
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.002 0.0019 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0041 0.0134
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Onchocerca volvulus 0.0055 0.0151 0.0753
Schistosoma mansoni 60S ribosomal protein L21 0.0017 0.0009 0.0018
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0151 0.029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0077 0.0267
Echinococcus granulosus sodium and chloride dependent glycine 0.0027 0.0046 0.0089
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0197 0.0679 0.2494
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0413 0.1486 0.4228
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.002 0.0019 0.0053
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Echinococcus granulosus acetylcholinesterase 0.0343 0.1224 0.2354
Echinococcus granulosus survival motor neuron protein 1 0.0483 0.1745 0.3358
Echinococcus granulosus lamin dm0 0.0056 0.0156 0.03
Brugia malayi hypothetical protein 0.0335 0.1195 0.349
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0056 0.0192
Leishmania major hypothetical protein, conserved 0.002 0.0019 0.0019
Schistosoma mansoni alpha-1 adrenergic receptor 0.0055 0.0151 0.029
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0019 0.0015 0.0029
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0086 0.0086
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0015 0.0029
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0055 0.0151 0.029
Entamoeba histolytica hypothetical protein 0.002 0.0019 0.0005
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0085 0.0163
Loa Loa (eye worm) hypoxia-induced factor 1 0.0309 0.1098 0.3208
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0014
Schistosoma mansoni gliotactin 0.0058 0.0161 0.0311
Echinococcus granulosus g-protein coupled receptor 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0184 0.0631 0.0631
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0019 0.0019
Chlamydia trachomatis thioredoxin reductase 0.0197 0.0679 0.2388
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.002 0.0019 0.0036
Brugia malayi Carboxylesterase family protein 0.0058 0.0161 0.0471
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0122 0.0235
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0058 0.0161 0.0459
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0019 0.0019
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0197 0.0679 0.0679
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.03
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.0151 0.029
Leishmania major dehydrogenase-like protein 0.002 0.0019 0.0019
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0356 0.0356
Echinococcus granulosus mitogen activated protein kinase 0.0104 0.0333 0.0641
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0055 0.0151 0.029
Brugia malayi phosphofructokinase 0.011 0.0356 0.1041
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0151 0.029
Echinococcus granulosus thioredoxin glutathione reductase 0.0933 0.3424 0.6588
Loa Loa (eye worm) hypothetical protein 0.0058 0.0161 0.0471
Mycobacterium ulcerans dehydrogenase 0.0197 0.0679 0.2506
Echinococcus multilocularis BC026374 protein (S09 family) 0.0058 0.0161 0.0311
Giardia lamblia Glutamate synthase 0.0197 0.0679 0.2455
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0027 0.0046 0.0135
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0959 0.3532
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0151 0.029
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0027 0.0046 0.0089
Onchocerca volvulus 0.0031 0.0061 0.0243
Brugia malayi Carboxylesterase family protein 0.0058 0.0161 0.0471
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Treponema pallidum sodium- and chloride- dependent transporter 0.0159 0.0539 0.1935
Schistosoma mansoni neuropeptide receptor 0.0055 0.0151 0.029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0051 0.0171
Echinococcus granulosus orexin receptor type 2 0.0055 0.0151 0.029
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0046 0.0089
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0272 0.0959 0.2802
Plasmodium falciparum steroid dehydrogenase, putative 0.002 0.0019 0.0041
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0184 0.0631 0.1842
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0197 0.0679 0.2455
Onchocerca volvulus 0.0055 0.0151 0.0753
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0197 0.0679 0.0679
Echinococcus multilocularis transfer RNA-Lys 0.0074 0.0221 0.0425
Brugia malayi hypothetical protein 0.002 0.0019 0.0055
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0176 0.0602 0.1159
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0197 0.0679 0.1931
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0927 0.3402 0.6545
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0741 0.2708 1
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.002 0.0019 0.0055
Echinococcus granulosus carbonyl reductase 1 0.002 0.0019 0.0036
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0197 0.0679 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0741 0.2708 0.7908
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0197 0.0679 0.1306
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0197 0.0679 0.2455
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0647 0.2375
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0611 0.2242
Schistosoma mansoni steroid dehydrogenase 0.002 0.0019 0.0036
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0019 0.0053
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0055 0.0151 0.029
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0741 0.2708 0.5209
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Mycobacterium ulcerans glutamate synthase subunit beta 0.0197 0.0679 0.2506
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0055 0.0151 0.044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0176 0.0338
Giardia lamblia Hypothetical protein 0.002 0.0019 0.0001
Schistosoma mansoni histamine h1 receptor 0.0055 0.0151 0.029
Brugia malayi MAP kinase sur-1 0.0104 0.0333 0.0973
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0058 0.0161 0.0311
Onchocerca volvulus 0.0058 0.0161 0.0814
Mycobacterium tuberculosis Carboxylesterase LipT 0.0058 0.0161 0.0459
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.002 0.0019 0.0053
Leishmania major hypothetical protein, conserved 0.002 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0055
Schistosoma mansoni inositol monophosphatase 0.0077 0.0234 0.045
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0015 0.0029
Brugia malayi 6-phosphofructokinase 0.011 0.0356 0.1041
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0026 0.0042 0.0081
Echinococcus multilocularis chromobox protein 1 0.0071 0.0209 0.0402
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0019 0.0015 0.0029
Echinococcus multilocularis G protein coupled receptor 139 0.0055 0.0151 0.029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0041 0.0134
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0093 0.0425
Leishmania major hypothetical protein, conserved 0.0016 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.006 0.0168 0.049
Mycobacterium ulcerans short-chain type oxidoreductase 0.002 0.0019 0.0069
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0028 0.0087
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0197 0.0679 0.1982
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0159 0.0539 0.1573
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.03
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0184 0.0631 0.1795
Onchocerca volvulus 0.0098 0.0313 0.1676
Echinococcus granulosus carboxylesterase 5A 0.0343 0.1224 0.2354
Onchocerca volvulus 0.0055 0.0151 0.0753
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0019 0.0069
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0184 0.0631 0.233
Brugia malayi RNA binding protein 0.0066 0.0191 0.0558
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Brugia malayi Carboxylesterase family protein 0.0058 0.0161 0.0471
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2696 1 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0197 0.0679 0.1982
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0019 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0611 0.2242
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.0356 0.1014
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0015 0.0029
Trypanosoma cruzi NADH dehydrogenase, putative 0.0197 0.0679 0.0679
Treponema pallidum thioredoxin reductase (trxB) 0.0197 0.0679 0.2455
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0077 0.0224
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0356 0.0686
Brugia malayi hypothetical protein 0.0027 0.0046 0.0135
Schistosoma mansoni sodium/chloride dependent transporter 0.0159 0.0539 0.1037
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2696 1 1
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0026 0.0042 0.0081
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0005 0.0014
Echinococcus multilocularis carboxylesterase 5A 0.0343 0.1224 0.2354
Entamoeba histolytica hypothetical protein 0.0037 0.0085 0.1008
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0151 0.029
Echinococcus granulosus sodium channel protein 0.0124 0.0409 0.0787
Brugia malayi hypothetical protein 0.0055 0.0151 0.044
Brugia malayi RE15519p 0.0055 0.0151 0.044
Onchocerca volvulus 0.0055 0.0151 0.0753
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.002 0.0019 0.0036
Schistosoma mansoni lipoxygenase 0.0247 0.0865 0.1665
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0014
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0055 0.0151 0.044
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0019 0.0053
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0019 0.0053
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.002 0.0019 0.0053
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Echinococcus multilocularis neuropeptide receptor 0.0055 0.0151 0.029
Leishmania major hypothetical protein, conserved 0.0027 0.0044 0.0044
Schistosoma mansoni amine GPCR 0.0055 0.0151 0.029
Echinococcus granulosus hypothetical protein 0.002 0.0019 0.0036
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0005 0.0014
Echinococcus granulosus carbonyl reductase 1 0.002 0.0019 0.0036
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0018 0.004
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.002 0.0019 0.0055
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0019 0.0069
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0028 0.0054
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0088 0.017
Echinococcus granulosus biogenic amine 5HT receptor 0.0183 0.0629 0.121
Onchocerca volvulus 0.0204 0.0706 0.3922
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0018 0.0051
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0005 0.0005
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0001 0.0002
Echinococcus granulosus death domain containing protein 0.003 0.0058 0.0111
Echinococcus multilocularis jun protein 0.026 0.0914 0.1759
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.0151 0.029
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0036 0.0078 0.0151
Brugia malayi ORL1-like opioid receptor 0.0055 0.0151 0.044
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0019 0.0041
Echinococcus granulosus peptide allatostatin:somatostatin 0.0055 0.0151 0.029
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.0151 0.044
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0019 0.0069
Toxoplasma gondii hypothetical protein 0.0027 0.0046 0.0135
Schistosoma mansoni amine GPCR 0.0055 0.0151 0.029
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.002 0.0019 0.0052
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0647 0.2375
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0151 0.029
Onchocerca volvulus 0.012 0.0394 0.2139
Echinococcus multilocularis neuropeptide receptor 0.0055 0.0151 0.029
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0005 0.0009
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0044 0.0116
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0055
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0028 0.0054
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0176 0.0338
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0027 0.0046 0.0089
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0184 0.0631 0.1214
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.002 0.0019 0.0036
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0027 0.0046 0.0089
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0197 0.0679 0.2506
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0959 0.3532
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.0356 0.0686
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0049 0.013 0.0378
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.002 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0043
Mycobacterium tuberculosis Probable oxidoreductase 0.0957 0.3516 1
Brugia malayi hypothetical protein 0.0055 0.0151 0.044
Echinococcus multilocularis fmrfamide receptor 0.0055 0.0151 0.029
Schistosoma mansoni biogenic amine (5HT) receptor 0.0183 0.0629 0.121
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0104 0.0333 0.0333
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0098 0.0313 0.0913
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.004 0.0093 0.0272
Schistosoma mansoni BC026374 protein (S09 family) 0.0058 0.0161 0.0311
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.003 0.0058 0.0111
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0123
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0055
Onchocerca volvulus 0.0055 0.0151 0.0753
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0018 0.0052
Mycobacterium ulcerans carveol-like dehydrogenase 0.002 0.0019 0.0069
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0014
Echinococcus granulosus tar DNA binding protein 0.0066 0.0191 0.0367
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0049 0.013 0.0249
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.002 0.0019 0.0053
Leishmania major trypanothione reductase 0.0933 0.3424 0.3424
Brugia malayi hypothetical protein 0.0123 0.0406 0.1185
Schistosoma mansoni neuropeptide f receptor 76f 0.0055 0.0151 0.029
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0005 0.0005
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0015 0.0043
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0197 0.0679 0.1306
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0055 0.0151 0.044
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0005 0.0009
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.026 0.0914 0.1759
Brugia malayi hypothetical protein 0.0055 0.0151 0.044
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0005 0.0009
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0027 0.0046 0.0089
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.0151 0.029
Brugia malayi dehydrogenases, short chain protein 2 0.002 0.0019 0.0055
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.0333 0.0333
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0056 0.0192
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0151 0.029
Echinococcus granulosus Ankyrin 0.003 0.0059 0.0113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0151 0.029
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0019 0.0069
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0192 0.0192
Giardia lamblia Kinase, CMGC MAPK 0.0104 0.0333 0.1171
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0056 0.0151
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0122 0.0122
Echinococcus multilocularis lipoxygenase domain containing protein 0.012 0.0394 0.0758
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0019 0.0053
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0019 0.0036
Echinococcus granulosus single minded 2 0.0077 0.0234 0.0451
Brugia malayi hypothetical protein 0.0204 0.0706 0.2063
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.0151 0.029
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0055 0.0151 0.029
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.002 0.0019 0.0036
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0055 0.0151 0.044
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0019 0.0069
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0197 0.0679 0.0679
Schistosoma mansoni biogenic amine receptor 0.0055 0.0151 0.029
Brugia malayi putative neuropeptide receptor NPR1 0.0055 0.0151 0.044
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0044 0.013
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0176 0.0338
Echinococcus granulosus sex peptide receptor 0.0055 0.0151 0.029
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0197 0.0679 0.1931
Onchocerca volvulus Glucosylceramidase homolog 0.0178 0.0611 0.3377
Entamoeba histolytica hypothetical protein 0.0037 0.0085 0.1008
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0154 0.052 0.1001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0079 0.0275
Schistosoma mansoni hypothetical protein 0.0055 0.0151 0.029
Brugia malayi Dehydrogenases, short chain protein 2 0.002 0.0019 0.0055
Schistosoma mansoni intermediate filament proteins 0.0056 0.0156 0.03
Schistosoma mansoni inositol monophosphatase 0.0077 0.0234 0.045
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0046 0.0089
Onchocerca volvulus 0.0058 0.0161 0.0814
Loa Loa (eye worm) carboxylesterase 0.0058 0.0161 0.0471
Brugia malayi bHLH-PAS transcription factor 0.0074 0.0221 0.0646
Echinococcus granulosus neuropeptide receptor 0.0055 0.0151 0.029
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0019 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0042 0.0139
Trypanosoma brucei protein kinase, putative 0.0104 0.0333 0.0333
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0197 0.0679 0.2506
Loa Loa (eye worm) hypothetical protein 0.0058 0.0161 0.0471
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0175 0.0646
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0019 0.0019
Mycobacterium tuberculosis Probable dehydrogenase 0.002 0.0019 0.0053
Loa Loa (eye worm) solute carrier family 6 member 4 0.0159 0.0539 0.1573
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0197 0.0679 0.1931
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0179
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2266 0.8396 0.8396
Brugia malayi chromobox protein homolog 3 0.004 0.0093 0.0272
Schistosoma mansoni sodium-dependent amino acid transporter 0.0027 0.0046 0.0089
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0122 0.0122
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.0151 0.029
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0044 0.0116
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0209 0.061
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.002 0.0019 0.0019
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.002 0.0019 0.0069
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0197 0.0679 0.0679
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.002 0.0019 0.0053
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0019 0.0005
Echinococcus multilocularis lamin 0.0056 0.0156 0.03
Giardia lamblia Reductase, putative 0.002 0.0019 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0093 0.0327
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0019 0.0069
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0019 0.0019
Echinococcus multilocularis sodium and chloride dependent glycine 0.0027 0.0046 0.0089
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Loa Loa (eye worm) carboxylesterase 0.0343 0.1224 0.3574
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.0151 0.044
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Loa Loa (eye worm) hypothetical protein 0.0058 0.0161 0.0471
Schistosoma mansoni retinal dehydrogenase 0.002 0.0019 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0611 0.2242
Echinococcus granulosus acetylcholinesterase 0.0343 0.1224 0.2354
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0041 0.0133
Schistosoma mansoni microtubule-associated protein tau 0.1408 0.5198 1
Schistosoma mansoni rab6-interacting 0.012 0.0394 0.0758
Schistosoma mansoni steroid dehydrogenase 0.002 0.0019 0.0036
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0191 0.0558
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0356 0.1301
Echinococcus granulosus Polycystic kidney disease protein 0.012 0.0394 0.0758
Echinococcus multilocularis thioredoxin glutathione reductase 0.0933 0.3424 0.6588
Leishmania major hypothetical protein, conserved 0.002 0.0019 0.0019
Leishmania major protein kinase, putative 0.0027 0.0046 0.0046
Echinococcus multilocularis microtubule associated protein 2 0.1408 0.5198 1
Trypanosoma cruzi hypothetical protein, conserved 0.0197 0.0679 0.0679
Loa Loa (eye worm) hypothetical protein 0.0058 0.0161 0.0471
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0046 0.0135
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.0151 0.029
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0019 0.0019
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1978 0.7322 0.7322
Giardia lamblia Thioredoxin reductase 0.0197 0.0679 0.2455
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0019 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0051 0.0171
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0019 0.0052
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0077 0.0267
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0019 0.0036
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0028 0.0054
Loa Loa (eye worm) hypothetical protein 0.0058 0.0161 0.0471
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0056 0.0192
Schistosoma mansoni short-chain dehydrogenase/reductase 0.002 0.0019 0.0036
Schistosoma mansoni adenoreceptor 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0135
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0058 0.017
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.002 0.0019 0.0053
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0197 0.0679 0.1979
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0055
Plasmodium falciparum transporter, putative 0.0027 0.0046 0.0121
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0611 0.2242
Loa Loa (eye worm) hypothetical protein 0.0483 0.1745 0.5097
Toxoplasma gondii oxidoreductase, putative 0.002 0.0019 0.0055
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0026 0.0042 0.0139
Schistosoma mansoni glutamate synthase 0.0197 0.0679 0.1306
Loa Loa (eye worm) programmed cell death 8 0.0197 0.0679 0.1982
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0197 0.0679 0.2494
Brugia malayi Inositol-1 0.0077 0.0234 0.0682
Echinococcus granulosus BC026374 protein S09 family 0.0058 0.0161 0.0311
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0019 0.0019
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.2266 0.8396 0.8396
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0058 0.0161 0.0311
Schistosoma mansoni biogenic amine receptor 0.0055 0.0151 0.029
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0027 0.0046 0.0135
Echinococcus multilocularis somatostatin receptor 0.0055 0.0151 0.029
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0197 0.0679 0.1982
Echinococcus multilocularis aryl hydrocarbon receptor 0.0026 0.0042 0.0081
Echinococcus granulosus somatostatin receptor 0.0055 0.0151 0.029
Schistosoma mansoni opsin-like receptor 0.0055 0.0151 0.029
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0611 0.2242
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0019 0.0019
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0143 0.0275
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0183 0.0629 0.1837
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Schistosoma mansoni jumonji domain containing protein 0.006 0.0168 0.0323
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0019 0.0019
Brugia malayi Death domain containing protein 0.003 0.0058 0.0168
Loa Loa (eye worm) hypothetical protein 0.0056 0.0156 0.0455
Onchocerca volvulus 0.0073 0.0219 0.114
Schistosoma mansoni single-minded 0.01 0.0318 0.0612
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0104 0.0333 0.0973
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0005 0.0005
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.0151 0.029
Brugia malayi jmjC domain containing protein 0.0016 0.0005 0.0014
Echinococcus granulosus para nitrobenzyl esterase 0.0058 0.0161 0.0311
Onchocerca volvulus 0.0055 0.0151 0.0753
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0197 0.0679 0.1982
Schistosoma mansoni steroid dehydrogenase 0.002 0.0019 0.0036
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0741 0.2708 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0055 0.0151 0.029
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0957 0.3516 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0741 0.2708 1
Onchocerca volvulus 0.0056 0.0156 0.0783
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0197 0.0679 0.2506
Brugia malayi Cyclic-nucleotide gated cation channel 0.0019 0.0015 0.0043
Echinococcus multilocularis oxidoreductase 0.002 0.0019 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0151 0.029
Echinococcus multilocularis dro:myosuppressin receptor 0.0055 0.0151 0.029
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0122 0.1568
Echinococcus multilocularis conserved hypothetical protein 0.0726 0.2655 0.5108
Echinococcus multilocularis serotonin receptor 0.0183 0.0629 0.121
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0042 0.0139
Mycobacterium tuberculosis Probable reductase 0.0413 0.1486 0.4228
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0055 0.0151 0.029
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0167 0.0321
Brugia malayi hypothetical protein 0.0055 0.0151 0.044
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0197 0.0679 0.0679
Echinococcus granulosus g protein coupled receptor 0.0055 0.0151 0.029
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0046 0.0089
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0151 0.029
Echinococcus granulosus serotonin transporter 0.0159 0.0539 0.1037
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Schistosoma mansoni amine GPCR 0.0055 0.0151 0.029
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.002 0.0019 0.0069
Echinococcus granulosus nuclear factor of activated T cells 5 0.0154 0.052 0.1001
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0019 0.0053
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0077 0.0234 0.0863
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0019 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0077 0.0267
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0019 0.0019
Plasmodium vivax SET domain protein, putative 0.0062 0.0176 0.0509
Echinococcus granulosus WW domain containing oxidoreductase 0.002 0.0019 0.0036
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0197 0.0679 0.1931
Echinococcus granulosus bloom syndrome protein 0.0022 0.0028 0.0054
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Echinococcus granulosus RUN 0.012 0.0394 0.0758
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.0151 0.029
Schistosoma mansoni amine GPCR 0.0055 0.0151 0.029
Loa Loa (eye worm) dehydrogenase 0.002 0.0019 0.0055
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0184 0.0631 0.1214
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Echinococcus granulosus neuropeptide receptor 0.0055 0.0151 0.029
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0175 0.0337
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.002 0.0019 0.0036
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0197 0.0679 0.2494
Onchocerca volvulus 0.0055 0.0151 0.0753
Echinococcus granulosus g protein coupled receptor 0.0055 0.0151 0.029
Trypanosoma brucei oxidoreductase-like protein 0.002 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0198 0.0684 0.1999
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0741 0.2708 0.7907
Loa Loa (eye worm) oxidoreductase 0.002 0.0019 0.0055
Echinococcus granulosus neuropeptide receptor A26 0.0055 0.0151 0.029
Echinococcus multilocularis g-protein coupled receptor 0.0055 0.0151 0.029
Brugia malayi hypothetical protein 0.0037 0.0085 0.0248
Onchocerca volvulus 0.0026 0.0042 0.0135
Echinococcus multilocularis allatostatin A receptor 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0388 0.1391 0.4063
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0055 0.0151 0.029
Brugia malayi larval opioid receptor 0.0055 0.0151 0.044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0033
Onchocerca volvulus 0.0055 0.0151 0.0753
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0077 0.0267
Schistosoma mansoni carbonyl reductase 0.002 0.0019 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0051 0.0171
Brugia malayi Melatonin receptor type 1A 0.0055 0.0151 0.044
Mycobacterium tuberculosis Possible ketoacyl reductase 0.002 0.0019 0.0053
Brugia malayi jmjC domain containing protein 0.0016 0.0005 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0741 0.2708 0.5209
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0191 0.0367
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0122 0.0235
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0175 0.0498
Toxoplasma gondii hypothetical protein 0.0027 0.0046 0.0135
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0135
Trichomonas vaginalis mercuric reductase, putative 0.0741 0.2708 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0019 0.0053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0151 0.029
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0019 0.0052
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0356 0.1041
Echinococcus granulosus intermediate filament protein 0.0056 0.0156 0.03
Brugia malayi Carboxylesterase family protein 0.0058 0.0161 0.0471
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0741 0.2708 1
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Schistosoma mansoni steroid dehydrogenase 0.002 0.0019 0.0036
Echinococcus multilocularis serotonin receptor 0.0183 0.0629 0.121
Brugia malayi hypothetical protein 0.0055 0.0151 0.044
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0175 0.0175
Loa Loa (eye worm) acetylcholinesterase 1 0.0343 0.1224 0.3574
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0151 0.029
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0019 0.0069
Schistosoma mansoni hypothetical protein 0.0176 0.0602 0.1159
Schistosoma mansoni ankyrin 23/unc44 0.003 0.0058 0.0111
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0056 0.0192
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0027 0.0046 0.0135
Entamoeba histolytica hypothetical protein 0.0037 0.0085 0.1008
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0197 0.0679 0.1931
Plasmodium falciparum ferrodoxin reductase-like protein 0.0197 0.0679 0.1971
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0005 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0042 0.0139
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.002 0.0019 0.0036
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0056 0.0053
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0019 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0135
Schistosoma mansoni hypothetical protein 0.012 0.0394 0.0758
Echinococcus multilocularis acetylcholinesterase 0.0343 0.1224 0.2354
Echinococcus multilocularis neuropeptide FF receptor 2 0.0055 0.0151 0.029
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0122 0.0356
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.002 0.0019 0.0055
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0056 0.0053
Schistosoma mansoni steroid dehydrogenase 0.002 0.0019 0.0036
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0016 0.0005 0.0009
Echinococcus multilocularis neuroligin 0.0058 0.0161 0.0311
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0019 0.0069
Echinococcus multilocularis neuropeptide s receptor 0.0055 0.0151 0.029
Brugia malayi jmjC domain containing protein 0.006 0.0168 0.049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0019 0.0019
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0055 0.0151 0.029
Schistosoma mansoni lipoxygenase 0.0463 0.1672 0.3217
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0085 0.0163
Brugia malayi neuropeptide F receptor 0.0055 0.0151 0.044
Echinococcus granulosus netrin receptor unc 5 0.003 0.0058 0.0111
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0197 0.0679 0.0679
Leishmania major short chain dehydrogenase, putative 0.002 0.0019 0.0019
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0005 0.0009
Mycobacterium ulcerans putative regulatory protein 0.0074 0.0221 0.0817
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0741 0.2708 0.2708
Echinococcus multilocularis transient receptor potential cation channel 0.002 0.0019 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0056 0.0192
Echinococcus multilocularis mitogen activated protein kinase 3 0.0104 0.0333 0.0641
Echinococcus granulosus mitogen activated protein kinase 3 0.0104 0.0333 0.0641
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0055 0.0151 0.044
Brugia malayi Tachykinin-like peptides receptor 99D 0.0055 0.0151 0.044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.03
Brugia malayi hypoxia-induced factor 1 0.0309 0.1098 0.3208
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.002 0.0019 0.0041
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.002 0.0019 0.0001
Plasmodium vivax multidomain scavenger receptor, putative 0.012 0.0394 0.1146
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0015 0.0029
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0016 0.0005 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0611 0.2242
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.002 0.0019 0.0019
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.0151 0.029
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0019 0.0036
Leishmania major hypothetical protein, conserved 0.0197 0.0679 0.0679
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0197 0.0679 0.0679
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0122 0.0434
Echinococcus granulosus carbonyl reductase 1 0.002 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0019 0.0019
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0741 0.2708 0.2708
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0027 0.0046 0.0015
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0056 0.0165
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0019 0.0019
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0019 0.0019
Echinococcus granulosus chromobox protein 1 0.0071 0.0209 0.0402
Brugia malayi Heterochromatin protein 1 0.0071 0.0209 0.061
Loa Loa (eye worm) RNA binding protein 0.0066 0.0191 0.0558
Echinococcus granulosus oxidoreductase 0.002 0.0019 0.0036
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0058 0.0168
Brugia malayi AKH receptor 0.0055 0.0151 0.044
Trypanosoma cruzi NADH dehydrogenase, putative 0.0197 0.0679 0.0679
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0122 0.0122
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0018 0.0039
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0197 0.0679 0.1306
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Brugia malayi sulfakinin receptor protein 0.0055 0.0151 0.044
Onchocerca volvulus 0.0055 0.0151 0.0753
Loa Loa (eye worm) hypothetical protein 0.0343 0.1224 0.3574
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0005 0.0009
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0104 0.0333 0.0973
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0197 0.0679 0.0679
Echinococcus granulosus neuroligin 0.0058 0.0161 0.0311
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1978 0.7322 0.7322
Loa Loa (eye worm) hypothetical protein 0.0026 0.0043 0.0126
Echinococcus granulosus hypothetical protein 0.0782 0.286 0.5503
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0192 0.0369
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0005 0.0005
Toxoplasma gondii NADPH-glutathione reductase 0.0741 0.2708 0.7908
Leishmania major C-8 sterol isomerase-like protein 0.0388 0.1391 0.1391
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Loa Loa (eye worm) TYRA-2 protein 0.0055 0.0151 0.044
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Echinococcus granulosus 6 phosphofructokinase 0.011 0.0356 0.0686
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0272 0.0959 0.2802
Plasmodium falciparum LCCL domain-containing protein 0.012 0.0394 0.1138
Trichomonas vaginalis glutathione reductase, putative 0.0741 0.2708 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0161 0.0471
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0041 0.0134
Brugia malayi hypothetical protein 0.0027 0.0044 0.013
Onchocerca volvulus Neuropeptide F receptor homolog 0.0055 0.0151 0.0753
Brugia malayi Thioredoxin reductase 0.0933 0.3424 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0064 0.0219
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0005 0.0009
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0019 0.0019
Schistosoma mansoni biogenic amine (5HT) receptor 0.0055 0.0151 0.029
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0197 0.0679 0.0679
Trichomonas vaginalis apoptosis inducing factor, putative 0.0197 0.0679 0.2494
Echinococcus multilocularis g protein coupled receptor 0.0055 0.0151 0.029
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0611 0.2242
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0741 0.2708 0.7905
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0197 0.0679 0.1306
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0027 0.0046 0.0089
Trypanosoma brucei NADH dehydrogenase 0.0197 0.0679 0.0679
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0741 0.2708 0.2708
Brugia malayi Dopamine receptor protein 2 0.0055 0.0151 0.044
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0049 0.013 0.0378
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.002 0.0019 0.0019
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0042 0.0139
Brugia malayi G-protein coupled receptor 0.0055 0.0151 0.044
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Brugia malayi Carboxylesterase family protein 0.0343 0.1224 0.3574
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Loa Loa (eye worm) thioredoxin reductase 0.0933 0.3424 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0741 0.2708 0.2708
Brugia malayi neuropeptide F receptor 0.0055 0.0151 0.044
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0027 0.0046 0.0089
Echinococcus granulosus lamin 0.0056 0.0156 0.03
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0197 0.0679 0.2455
Schistosoma mansoni neuroligin 3 (S09 family) 0.0058 0.0161 0.0311
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0046 0.0089
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0151 0.029
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0197 0.0679 0.1306
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0019 0.0069
Brugia malayi 6-phosphofructokinase 0.011 0.0357 0.1042
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0028 0.0082
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0046 0.0046
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0959 0.3532
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.0151 0.029
Brugia malayi G-protein coupled receptor 0.0055 0.0151 0.044
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0005 0.0009
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0055 0.0151 0.029
Onchocerca volvulus 0.0197 0.0679 0.3764
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0544 0.1975 0.5767
Schistosoma mansoni steroid dehydrogenase 0.002 0.0019 0.0036
Mycobacterium ulcerans NADH dehydrogenase 0.0197 0.0679 0.2506
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0042 0.0139
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0056 0.0192
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0044 0.0044
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0175 0.0337
Plasmodium falciparum glutathione reductase 0.0933 0.3424 1
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0015 0.0029
Schistosoma mansoni biogenic amine receptor 0.0055 0.0151 0.029
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0058 0.017
Brugia malayi intermediate filament protein 0.0056 0.0156 0.0455
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0019 0.0069
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0019 0.0053
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.002 0.0019 0.0053
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0077 0.0234 0.0234
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0019 0.0053
Echinococcus multilocularis g protein coupled receptor 0.0055 0.0151 0.029
Echinococcus granulosus G protein coupled receptor 139 0.0055 0.0151 0.029
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.0333 0.0333
Loa Loa (eye worm) hypothetical protein 0.0491 0.1776 0.5188
Schistosoma mansoni netrin receptor unc5 0.003 0.0058 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.005 0.0168
Schistosoma mansoni chromobox protein 0.0071 0.0209 0.0402
Loa Loa (eye worm) hypothetical protein 0.012 0.0394 0.115
Leishmania major short chain dehydrogenase-like protein 0.002 0.0019 0.0019
Toxoplasma gondii carbonyl reductase 1, putative 0.002 0.0019 0.0055
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0741 0.2708 0.7908
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0175 0.0511
Mycobacterium ulcerans oxidoreductase 0.002 0.0019 0.0069
Schistosoma mansoni amine GPCR 0.0578 0.2102 0.4043
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Leishmania major protein kinase, putative 0.0032 0.0065 0.0065
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0055 0.0151 0.029
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0077 0.0234 0.0234
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0046 0.0135
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0019 0.0019
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0122 0.0356
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.002 0.0019 0.0055
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0058 0.0161 0.058
Echinococcus granulosus steroid dehydrogenase 0.002 0.0019 0.0036
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0019 0.0019
Onchocerca volvulus 0.0055 0.0151 0.0753
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0005 0.0009
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0104 0.0333 0.0333
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0026 0.0042 0.0123
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0019 0.0005
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0019 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0191 0.0367
Onchocerca volvulus 0.0058 0.0161 0.0814
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.0356 0.1316
Echinococcus multilocularis conserved hypothetical protein 0.002 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.003 0.0058 0.0111
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0005 0.0014
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0957 0.3516 1
Plasmodium vivax hypothetical protein, conserved 0.002 0.0019 0.005
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.002 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0253 0.0888 0.2593
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0005 0.0014
Schistosoma mansoni neuropeptide receptor 0.0055 0.0151 0.029
Schistosoma mansoni short chain dehydrogenase 0.002 0.0019 0.0036
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0055 0.0151 0.044
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Loa Loa (eye worm) hypothetical protein 0.003 0.0059 0.0171
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0018 0.0018
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0018 0.0068
Echinococcus granulosus lipoxygenase domain containing protein 0.012 0.0394 0.0758
Echinococcus multilocularis RUN 0.012 0.0394 0.0758
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0463 0.1672 0.3217
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0151 0.029
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.0356 0.1014
Echinococcus multilocularis mitogen activated protein kinase 0.0104 0.0333 0.0641
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0122 0.0434
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0019 0.0055
Toxoplasma gondii oxidoreductase, putative 0.002 0.0019 0.0055
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0015 0.0029
Brugia malayi Doublecortin family protein 0.012 0.0394 0.115
Onchocerca volvulus 0.0058 0.0161 0.0814
Loa Loa (eye worm) RecQ helicase 0.0022 0.0028 0.0082
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0015 0.0029
Schistosoma mansoni carbonyl reductase 0.002 0.0019 0.0036
Brugia malayi hypothetical protein 0.0483 0.1745 0.5097
Leishmania major hypothetical protein, conserved 0.0197 0.0679 0.0679
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0046 0.0089
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Loa Loa (eye worm) oxidoreductase 0.002 0.0019 0.0055
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0122 0.0122
Schistosoma mansoni disulfide oxidoreductase 0.0197 0.0679 0.1306
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0933 0.3424 0.974
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0019 0.0036
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0019 0.0052
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0197 0.0679 0.1982
Echinococcus granulosus inositol monophosphatase 1 0.0077 0.0234 0.045
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0077 0.0234 0.0682
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0333 0.1216
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0056 0.0577
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0019 0.0053
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0056 0.0165
Brugia malayi Pre-SET motif family protein 0.043 0.155 0.4525
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0209 0.0756
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0191 0.0558
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0055 0.0151 0.0753
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.0168 0.0323
Trypanosoma cruzi trypanothione reductase, putative 0.0741 0.2708 0.2708
Loa Loa (eye worm) serotonin transporter b 0.0159 0.0539 0.1573
Echinococcus multilocularis sex peptide receptor 0.0055 0.0151 0.029
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0019 0.0069
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0019 0.0019
Mycobacterium leprae Probable oxidoreductase 0.002 0.0019 0.0053
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0197 0.0679 0.1306
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0085 0.0163
Plasmodium vivax glutathione reductase, putative 0.0933 0.3424 1
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0015 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0151 0.029
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0026 0.0042 0.0139
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0197 0.0679 0.2494
Echinococcus granulosus tm gpcr rhodopsin 0.0927 0.3402 0.6545
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0151 0.029
Loa Loa (eye worm) hypothetical protein 0.0055 0.0151 0.044
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0957 0.3516 1
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0005 0.0005
Plasmodium vivax amine transporter, putative 0.0027 0.0046 0.0131
Echinococcus multilocularis fmrfamide receptor 0.0055 0.0151 0.029
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0388 0.1391 0.1391
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.005 0.0168
Echinococcus granulosus serotonin receptor 0.0055 0.0151 0.029

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 Insecticidal activity against Myzus persicae Sulzer in raddish plant assessed as mortality at 250 ppm by systemic plant assay ChEMBL. 18207749
Activity (functional) = 65 % Insecticidal activity against Myzus persicae Sulzer in raddish plant assessed as mortality at 100 ppm ChEMBL. 18207749
Activity (functional) = 89 % Insecticidal activity against Aphis gossypii glover in cotton/melon plant assessed as mortality at 100 ppm ChEMBL. 18207749
EC50 (functional) < 100 ppm Insecticidal activity against Aphis gossypii glover in cotton/melon plant ChEMBL. 18207749
EC50 (functional) < 100 ppm Insecticidal activity against Myzus persicae Sulzer in raddish plant ChEMBL. 18207749

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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