Detailed information for compound 514892

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 254.301 | Formula: C9H18O6S
  • H donors: 5 H acceptors: 6 LogP: -1.44 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]([C@@H](C[S+]1C[C@H]([C@@H]([C@H]1CO)O)O)O)[O-]
  • InChi: 1S/C9H18O6S/c10-1-5(12)6(13)3-16-4-7(14)9(15)8(16)2-11/h5-11,13-15H,1-4H2/t5-,6+,7+,8+,9-,16?/m0/s1
  • InChiKey: RPLSMILMVIUFAQ-VVWMKKEXSA-N  

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase Starlite/ChEMBL References
Rattus norvegicus Sucrase-isomaltase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis glycogen debranching enzyme Get druggable targets OG5_128837 All targets in OG5_128837
Schistosoma japonicum Glycogen debranching enzyme, putative Get druggable targets OG5_128837 All targets in OG5_128837
Schistosoma japonicum ko:K00705 4-alpha-glucanotransferase [EC2.4.1.25], putative Get druggable targets OG5_128837 All targets in OG5_128837
Candida albicans closely related to C. albicans GCA1 cell wall mannoprotein glycosyl hydrolase Get druggable targets OG5_127055 All targets in OG5_127055
Echinococcus granulosus lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Brugia malayi Glycosyl hydrolases family 31 protein Get druggable targets OG5_127055 All targets in OG5_127055
Cryptosporidium parvum Gdb1p; glycogen debranching enzyme Get druggable targets OG5_128837 All targets in OG5_128837
Schistosoma mansoni hypothetical protein Get druggable targets OG5_128837 All targets in OG5_128837
Candida albicans closely related to C. albicans GCA1 cell wall mannoprotein glycosyl hydrolase Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans cell wall mannoprotein glycosyl hydrolase whose expression increases in presence of galatose Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Neospora caninum glycogen debranching enzyme, putative Get druggable targets OG5_128837 All targets in OG5_128837
Loa Loa (eye worm) glycosyl hydrolase family 31 protein Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans similar to S. cerevisiae GDB1 (YPR184W) glycogen debranching enzyme Get druggable targets OG5_128837 All targets in OG5_128837
Schistosoma japonicum Glycogen debranching enzyme, putative Get druggable targets OG5_128837 All targets in OG5_128837
Schistosoma japonicum Glycogen debranching enzyme, putative Get druggable targets OG5_128837 All targets in OG5_128837
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Giardia lamblia 4-alpha-glucanotransferase, amylo-alpha-1,6-glucosidase Get druggable targets OG5_128837 All targets in OG5_128837
Brugia malayi Amylo-alpha-1,6-glucosidase family protein Get druggable targets OG5_128837 All targets in OG5_128837
Trichomonas vaginalis glycogen debranching enzyme, putative Get druggable targets OG5_128837 All targets in OG5_128837
Brugia malayi hypothetical protein Get druggable targets OG5_128837 All targets in OG5_128837
Candida albicans cell wall mannoprotein glycosyl hydrolase whose expression increases in presence of galatose Get druggable targets OG5_127055 All targets in OG5_127055
Toxoplasma gondii Amylo-alpha-1,6-glucosidase Get druggable targets OG5_128837 All targets in OG5_128837
Echinococcus multilocularis lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Loa Loa (eye worm) amylo-alpha-1,6-glucosidase Get druggable targets OG5_128837 All targets in OG5_128837
Echinococcus granulosus glycogen debranching enzyme Get druggable targets OG5_128837 All targets in OG5_128837
Schistosoma mansoni hypothetical protein Get druggable targets OG5_128837 All targets in OG5_128837
Cryptosporidium hominis glycine-rich protein 2 (GRP2) Get druggable targets OG5_128837 All targets in OG5_128837
Schistosoma japonicum ko:K01187 alpha-glucosidase [EC3.2.1.20], putative Get druggable targets OG5_127055 All targets in OG5_127055
Trichomonas vaginalis glycogen debranching enzyme, putative Get druggable targets OG5_128837 All targets in OG5_128837
Schistosoma japonicum Lysosomal alpha-glucosidase precursor, putative Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans hypothetical protein Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma mansoni alpha-glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Echinococcus multilocularis lysosomal alpha glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Schistosoma mansoni alpha-glucosidase Get druggable targets OG5_127055 All targets in OG5_127055
Candida albicans similar to S. cerevisiae GDB1 (YPR184W) glycogen debranching enzyme Get druggable targets OG5_128837 All targets in OG5_128837
Entamoeba histolytica glycogen debranching enzyme, putative Get druggable targets OG5_128837 All targets in OG5_128837
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128837 All targets in OG5_128837
Onchocerca volvulus Get druggable targets OG5_127055 All targets in OG5_127055

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0236 0.0236
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0082 0.0755 0.1391
Brugia malayi Calcium binding EGF domain containing protein 0.0071 0.0633 0.0653
Onchocerca volvulus Slit protein homolog 0.0027 0.0126 0.0043
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0487 0.5427 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0098 0.0941 0.0969
Loa Loa (eye worm) Notch2 0.0027 0.0126 0.013
Loa Loa (eye worm) transcription factor SMAD2 0.0098 0.0941 0.0969
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0157 0.1626 1
Onchocerca volvulus 0.0069 0.0611 0.0548
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0487 0.5427 0.5591
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0923 0.1603
Onchocerca volvulus Putative cubilin 0.004 0.0275 0.0198
Schistosoma mansoni hypothetical protein 0.0069 0.0611 0.0611
Echinococcus granulosus PHD finger protein rhinoceros 0.0093 0.0882 0.1625
Brugia malayi SET domain containing protein 0.0029 0.0149 0.0153
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0103 0.0121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Echinococcus granulosus enteropeptidase 0.0101 0.0973 0.1794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0139
Echinococcus granulosus protein jagged 1 0.0027 0.0126 0.0232
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0146 0.0173
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0082 0.0755 0.1391
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0103 0.0121
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0653 0.0772
Brugia malayi CUB domain containing protein 0.0026 0.0107 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0025 0.01 0.01
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0025 0.0103 0.0189
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0064 0.0551 0.0568
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Loa Loa (eye worm) beta-lactamase 0.0073 0.0653 0.0673
Echinococcus granulosus neurogenic locus notch protein 0.0027 0.0126 0.0232
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0377 0.0388
Schistosoma mansoni hypothetical protein 0.0093 0.0882 0.0882
Brugia malayi Trypsin family protein 0.0857 0.9706 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0366 0.4037 0.4159
Loa Loa (eye worm) hypothetical protein 0.0096 0.0924 0.0952
Echinococcus granulosus Mastin 0.0101 0.0973 0.1794
Echinococcus granulosus protein jagged 2 0.0027 0.0126 0.0232
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0164 0.0194
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1268 0.7641
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0082 0.0755 0.0778
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0025 0.0103 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0139
Echinococcus multilocularis protein jagged 2 0.0027 0.0126 0.0232
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0653 0.1204
Onchocerca volvulus 0.0067 0.0591 0.0527
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0092 0.0871 0.0871
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.006 0.0502 0.0594
Schistosoma mansoni jumonji/arid domain-containing protein 0.0113 0.1122 0.1122
Schistosoma mansoni jumonji/arid domain-containing protein 0.0113 0.1122 0.1122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Brugia malayi Delta serrate ligand family protein 0.0027 0.0126 0.013
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0157 0.1626 0.2987
Echinococcus granulosus L aminoadipate semialdehyde 0.0092 0.0871 0.1605
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0653 0.0772
Echinococcus granulosus Chromo domain 0.0025 0.0103 0.0189
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.011 0.0203
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0653 0.0823
Echinococcus multilocularis fibrillin 1 0.0071 0.0633 0.1167
Trypanosoma brucei glycosyl hydrolase-like protein 0.0047 0.036 0.0454
Echinococcus granulosus chromobox protein 1 0.0154 0.1584 0.2919
Echinococcus multilocularis dnaJ subfamily B 0.0335 0.3678 0.6778
Echinococcus multilocularis L aminoadipate semialdehyde 0.0092 0.0871 0.1605
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0092 0.0871 0.0897
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0126 0.1268 0.2337
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0027 0.0027
Echinococcus multilocularis fibropellin Ia 0.0027 0.0126 0.0232
Schistosoma mansoni laminin gamma-3 chain 0.0027 0.0126 0.0126
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0653 0.107
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Schistosoma mansoni chromobox protein 0.0025 0.0103 0.0103
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0103 0.0189
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.0755 0.0951
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0136 0.016
Schistosoma mansoni survival motor neuron protein 0.0047 0.0355 0.0355
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Onchocerca volvulus 0.0101 0.0973 0.0924
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0908 0.0908
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0653 0.0673
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0002 0.0002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0087 0.0812 0.1383
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0037 0.0236 0.0436
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0061 0.0521 0.0537
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Trichomonas vaginalis chromobox protein, putative 0.0093 0.0881 0.1041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Schistosoma mansoni hypothetical protein 0.0113 0.1117 0.1117
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0047 0.036 0.0425
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0251 0.0278
Schistosoma mansoni cellular tumor antigen P53 0.0035 0.022 0.022
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0653 0.107
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Onchocerca volvulus 0.0027 0.0126 0.0043
Echinococcus granulosus chromobox protein 1 0.0154 0.1584 0.2919
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Plasmodium falciparum heterochromatin protein 1 0.0025 0.0103 0.0189
Echinococcus granulosus neuropeptide s receptor 0.0381 0.4205 0.7748
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0037 0.0236 0.0244
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0121
Mycobacterium tuberculosis Conserved protein 0.0073 0.0653 0.107
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0092 0.0871 0.0897
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0487 0.5427 0.6839
Loa Loa (eye worm) hypothetical protein 0.003 0.0158 0.0163
Loa Loa (eye worm) hypothetical protein 0.0071 0.0633 0.0653
Echinococcus multilocularis CREB binding protein 0.0057 0.047 0.0865
Brugia malayi Bromodomain containing protein 0.0094 0.0898 0.0926
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0084 0.0779 0.0802
Echinococcus multilocularis transmembrane protease serine 3 0.0101 0.0973 0.1794
Echinococcus granulosus neutral alpha glucosidase AB 0.0082 0.0755 0.1391
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Brugia malayi AF-10 protein 0.003 0.0162 0.0167
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0653 0.0823
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Loa Loa (eye worm) hypothetical protein 0.0159 0.1645 0.1695
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0026 0.0118 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.015 0.0177
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0071 0.0633 0.0653
Onchocerca volvulus 0.075 0.8463 0.8708
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0101 0.0973 0.1794
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0101 0.0973 0.1003
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0047 0.036 0.0425
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0086 0.0806 0.075
Onchocerca volvulus Alhambra homolog 0.0093 0.0882 0.0829
Entamoeba histolytica glycogen debranching enzyme, putative 0.0157 0.1618 0.2982
Loa Loa (eye worm) hypothetical protein 0.0194 0.2051 0.2113
Echinococcus multilocularis lysosomal alpha glucosidase 0.0366 0.4037 0.7439
Trichomonas vaginalis chromobox protein, putative 0.0093 0.0881 0.1041
Echinococcus granulosus GPCR family 2 0.0061 0.0521 0.096
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0026 0.0118 0.0218
Brugia malayi Glycosyl hydrolases family 31 protein 0.0366 0.4037 0.4159
Schistosoma mansoni alpha glucosidase 0.0082 0.0755 0.0755
Trichomonas vaginalis sucrase-isomaltase, putative 0.0082 0.0755 0.0892
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Schistosoma mansoni hypothetical protein 0.0047 0.0355 0.0355
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0044 0.0322 0.0592
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0146 0.0173
Loa Loa (eye worm) hypothetical protein 0.0035 0.022 0.0226
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Loa Loa (eye worm) jmjC domain-containing protein 0.0113 0.1122 0.1156
Echinococcus multilocularis neurogenic locus notch protein 0.0027 0.0126 0.0232
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0653 0.1034
Trichomonas vaginalis glycogen debranching enzyme, putative 0.0157 0.1618 0.1912
Echinococcus multilocularis protein jagged 1 0.0027 0.0126 0.0232
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.006 0.0502 0.0594
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0064 0.0551 0.1015
Onchocerca volvulus Arrow homolog 0.0084 0.0779 0.0722
Schistosoma mansoni lipoxygenase 0.0044 0.0322 0.0322
Onchocerca volvulus 0.0027 0.0126 0.0043
Trypanosoma brucei trypanothione reductase 0.0038 0.0251 0.0316
Brugia malayi Calcium binding EGF domain containing protein 0.004 0.0275 0.0283
Loa Loa (eye worm) amylo-alpha-1,6-glucosidase 0.0076 0.0692 0.0713
Schistosoma mansoni chromobox protein 0.0154 0.1584 0.1584
Trypanosoma cruzi hypothetical protein, conserved 0.0191 0.2014 0.2539
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0653 0.3583
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Schistosoma mansoni CREB-binding protein 2 0.0083 0.0771 0.0771
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0002 0.0002
Brugia malayi Muscle positioning protein 4 0.0096 0.0924 0.0952
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0487 0.5427 0.6413
Echinococcus granulosus fibropellin Ia 0.0027 0.0126 0.0232
Brugia malayi Cadherin domain containing protein 0.0027 0.0126 0.013
Plasmodium falciparum phd finger protein, putative 0.0093 0.0882 0.1625
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0189
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0377 0.0377
Brugia malayi PHD-finger family protein 0.0093 0.0882 0.0908
Echinococcus multilocularis lysine specific demethylase 5A 0.0112 0.1107 0.2039
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0095 0.0908 0.0936
Mycobacterium tuberculosis Conserved protein 0.0073 0.0653 0.107
Onchocerca volvulus 0.0027 0.0126 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0377 0.0445
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0653 0.0653
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.0973
Brugia malayi hypothetical protein 0.0101 0.0973 0.1003
Onchocerca volvulus 0.0101 0.0973 0.0924
Echinococcus granulosus tumor protein p63 0.0241 0.2594 0.478
Entamoeba histolytica hypothetical protein 0.0025 0.0103 0.0189
Brugia malayi Trypsin family protein 0.0101 0.0973 0.1003
Loa Loa (eye worm) hypothetical protein 0.0061 0.0521 0.0537
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1268 0.7641
Brugia malayi Valyl-tRNA synthetase 0.0025 0.0103 0.0106
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0251 0.0462
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Toxoplasma gondii kringle domain-containing protein 0.0191 0.2014 0.3712
Toxoplasma gondii calcium binding egf domain-containing protein 0.0071 0.0633 0.1167
Leishmania major alpha glucosidase II subunit, putative 0.0082 0.0755 0.1391
Schistosoma mansoni voltage-gated potassium channel 0.007 0.0619 0.0619
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0465 0.5183 1
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0487 0.5427 0.5591
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1268 0.1268
Trichomonas vaginalis chromobox protein, putative 0.0154 0.1584 0.1872
Mycobacterium tuberculosis Probable dehydrogenase 0.0087 0.0812 0.1383
Echinococcus multilocularis laminin 0.0071 0.0633 0.1167
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0487 0.5427 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1268 0.7641
Toxoplasma gondii aldehyde dehydrogenase 0.0126 0.1268 0.2337
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0139
Brugia malayi Glycosyl hydrolases family 31 protein 0.0082 0.0755 0.0778
Plasmodium falciparum thioredoxin reductase 0.0038 0.0251 0.0462
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0653 0.0772
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0019 0.0027 0.0027
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0251 0.0462
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0084 0.0782 0.0782
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0653 0.107
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0303 0.3314 0.6107
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0002 0.0002
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0103 0.0121
Toxoplasma gondii histone lysine demethylase JMJD6a 0.003 0.0158 0.0291
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0103 0.0189
Brugia malayi jmjC domain containing protein 0.003 0.0158 0.0163
Leishmania major trypanothione reductase 0.0038 0.0251 0.0462
Onchocerca volvulus 0.0101 0.0973 0.0924
Brugia malayi jmjC domain containing protein 0.003 0.0158 0.0163
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0653 0.0653
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0173 0.0319
Loa Loa (eye worm) glutathione reductase 0.0038 0.0251 0.0258
Schistosoma mansoni chromobox protein 0.0154 0.1584 0.1584
Onchocerca volvulus 0.012 0.1198 0.1158
Brugia malayi glutathione reductase 0.0038 0.0251 0.0258
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0487 0.5427 1
Onchocerca volvulus 0.0025 0.0103 0.0019
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Echinococcus multilocularis Tolloid protein 1 0.0084 0.0782 0.1441
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0516 0.0609
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0251 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0377 0.0475
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0121
Loa Loa (eye worm) notch protein 0.0027 0.0126 0.013
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0487 0.5427 0.6413
Onchocerca volvulus 0.0096 0.0924 0.0873
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0131 0.0155
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0047 0.0059
Echinococcus granulosus cpg binding protein 0.0025 0.01 0.0184
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0162 0.0204
Echinococcus multilocularis protein jagged 1 0.0027 0.0126 0.0232
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.012 0.1198 0.1198
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0882 0.1625
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0079 0.01
Onchocerca volvulus 0.0027 0.0126 0.0043
Onchocerca volvulus 0.0101 0.0973 0.0924
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0002
Loa Loa (eye worm) CHromoDomain protein family member 0.0026 0.0118 0.0122
Loa Loa (eye worm) helicase 0.0025 0.0103 0.0106
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0101 0.0973 0.1794
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0087 0.0812 0.1383
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0516 0.0609
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.015 0.0177
Brugia malayi jmjC domain containing protein 0.003 0.0158 0.0163
Echinococcus multilocularis neurogenic locus protein delta 0.0027 0.0126 0.0232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0377 0.0445
Loa Loa (eye worm) trypsin family protein 0.0101 0.0973 0.1003
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0487 0.5427 1
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0032 0.0179 0.0329
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.015 0.0177
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0377 0.0694
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0173 0.0319
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Echinococcus multilocularis fat cadherin tumor suppressor 0.0027 0.0126 0.0232
Schistosoma mansoni jumonji domain containing protein 0.003 0.0158 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Brugia malayi beta-lactamase 0.0073 0.0653 0.0673
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0377 0.0694
Echinococcus multilocularis phd:f box containing protein 0.003 0.0158 0.0291
Schistosoma mansoni chromobox protein 0.0025 0.0103 0.0103
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0086 0.0806 0.083
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0322 0.3524 0.6494
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Echinococcus multilocularis neutral alpha glucosidase AB 0.0082 0.0755 0.1391
Onchocerca volvulus 0.0069 0.0611 0.0548
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0103 0.0121
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0162 0.0299
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.003 0.0158 0.0158
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.0973
Brugia malayi Fibulin-1 precursor 0.0071 0.0633 0.0653
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Echinococcus multilocularis chromobox protein 2 0.0025 0.0103 0.0189
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Brugia malayi notch-like transmembrane receptor 0.0027 0.0126 0.013
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0064 0.0551 0.0568
Brugia malayi CXXC zinc finger family protein 0.0024 0.0084 0.0087
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0739 0.0874
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0236 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Schistosoma mansoni alpha-glucosidase 0.0332 0.3642 0.3642
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0377 0.0475
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0027 0.0049
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0487 0.5427 0.5427
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0162 0.0204
Brugia malayi Associated with TFs and helicases family protein 0.0025 0.0103 0.0106
Echinococcus granulosus neurogenic locus notch protein 4 0.0027 0.0126 0.0232
Brugia malayi jmjC domain containing protein 0.003 0.0158 0.0163
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Onchocerca volvulus 0.0857 0.9706 1
Echinococcus granulosus jumonji domain containing 1A 0.003 0.0158 0.0291
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0061 0.0521 0.096
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0103 0.00000000014506
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0487 0.5427 0.6839
Echinococcus multilocularis neuropeptide s receptor 0.0381 0.4205 0.7748
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0806 0.0952
Brugia malayi Latrophilin receptor protein 2 0.0061 0.0521 0.0537
Schistosoma mansoni mixed-lineage leukemia protein mll 0.004 0.027 0.027
Echinococcus granulosus Tolloid protein 1 0.0084 0.0782 0.1441
Loa Loa (eye worm) hypothetical protein 0.0032 0.0178 0.0183
Trichomonas vaginalis maltase-glucoamylase, putative 0.0047 0.036 0.0425
Mycobacterium ulcerans hypothetical protein 0.0073 0.0653 0.3583
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Brugia malayi Amylo-alpha-1,6-glucosidase family protein 0.0157 0.1618 0.1668
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.011 0.0203
Echinococcus multilocularis jumonji domain containing 1A 0.003 0.0158 0.0291
Schistosoma mansoni cpg binding protein 0.0024 0.0084 0.0084
Onchocerca volvulus 0.0101 0.0973 0.0924
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Schistosoma mansoni cpg binding protein 0.0025 0.01 0.01
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0251 0.0258
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0101 0.0973 0.1794
Mycobacterium ulcerans hypothetical protein 0.0101 0.0973 0.5695
Loa Loa (eye worm) hypothetical protein 0.0056 0.0453 0.0467
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Brugia malayi Protein cec-1. 0.0025 0.0103 0.0106
Loa Loa (eye worm) hypothetical protein 0.0084 0.0779 0.0802
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Echinococcus granulosus protein jagged 1 0.0027 0.0126 0.0232
Loa Loa (eye worm) hypothetical protein 0.0084 0.0782 0.0806
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0103 0.0103
Echinococcus multilocularis notch 0.0027 0.0126 0.0232
Loa Loa (eye worm) hypothetical protein 0.0067 0.0591 0.0609
Plasmodium falciparum JmjC domain-containing protein, putative 0.003 0.0158 0.0291
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.0862 0.1588
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0653 0.3583
Echinococcus multilocularis cpg binding protein 0.0025 0.01 0.0184
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0026 0.0118 0.0118
Loa Loa (eye worm) TK/ROR protein kinase 0.0191 0.2014 0.2075
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0084 0.0782 0.0806
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0377 0.0694
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0027 0.0126 0.013
Loa Loa (eye worm) DOMON domain-containing protein 0.0069 0.0611 0.063
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0025 0.0103 0.0106
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0027
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0653 0.3583
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0027 0.0049
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.011 0.0014
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.0973
Loa Loa (eye worm) CXXC zinc finger family protein 0.0024 0.0084 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0377 0.0445
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Echinococcus granulosus lysosomal alpha glucosidase 0.0366 0.4037 0.7439
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0087 0.0812 0.1383
Schistosoma mansoni jumonji domain containing protein 0.0241 0.2594 0.2594
Schistosoma mansoni phosphatidylserine receptor 0.003 0.0158 0.0158
Entamoeba histolytica hypothetical protein 0.0026 0.011 0.0203
Loa Loa (eye worm) hypothetical protein 0.0157 0.1618 0.1668
Brugia malayi Cadherin domain containing protein 0.0027 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0047 0.036 0.0371
Schistosoma mansoni voltage-gated potassium channel 0.007 0.0619 0.0619
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0136 0.016
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0659 0.7413 0.7638
Trypanosoma brucei Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0908 0.1673
Toxoplasma gondii thioredoxin reductase 0.0038 0.0251 0.0462
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.011 0.0203
Schistosoma mansoni hypothetical protein 0.0101 0.0973 0.0973
Echinococcus granulosus Chromobox protein 3 0.0025 0.0103 0.0189
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0096 0.0923 0.1603
Echinococcus multilocularis chromobox protein 1 0.0154 0.1584 0.2919
Echinococcus granulosus glycoprotein Antigen 5 0.0101 0.0973 0.1794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0908 0.0908
Brugia malayi M-phase phosphoprotein, mpp8 0.0025 0.0103 0.0106
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0322 0.3524 0.6494
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0087 0.0812 0.4629
Schistosoma mansoni hypothetical protein 0.0061 0.0521 0.0521
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0236 0.0236
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0164 0.0194
Toxoplasma gondii calcium binding egf domain-containing protein 0.0071 0.0633 0.1167
Echinococcus granulosus survival motor neuron protein 1 0.023 0.2471 0.4553
Echinococcus granulosus phd:f box containing protein 0.003 0.0158 0.0291
Brugia malayi Protein kinase domain containing protein 0.0191 0.2014 0.2075
Mycobacterium tuberculosis Conserved protein 0.0073 0.0653 0.107
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0037 0.0236 0.0244
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0103 0.0103
Onchocerca volvulus 0.0069 0.0611 0.0548
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0653 0.0673
Echinococcus granulosus CREB binding protein 0.0051 0.0404 0.0744
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0103 0.0103
Schistosoma mansoni hypothetical protein 0.0133 0.1343 0.1343
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0064 0.0551 0.1015
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0158 0.0163
Onchocerca volvulus 0.0069 0.0611 0.0548
Echinococcus granulosus neuropeptide receptor A26 0.0381 0.4205 0.7748
Toxoplasma gondii ABC1 family protein 0.0073 0.0653 0.1204
Loa Loa (eye worm) PHD-finger family protein 0.0093 0.0882 0.0908
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.1794
Echinococcus multilocularis neuropeptide receptor A26 0.0381 0.4205 0.7748
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0158 0.0163
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0653 0.107
Echinococcus granulosus slit 2 protein 0.0027 0.0126 0.0232
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.011 0.5
Schistosoma mansoni hypothetical protein 0.0335 0.3678 0.3678
Brugia malayi jmjC domain containing protein 0.0303 0.3314 0.3414
Schistosoma mansoni hypothetical protein 0.0061 0.0521 0.0521
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0138
Brugia malayi SEA domain containing protein 0.0069 0.0611 0.063
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0191 0.2014 0.3591
Brugia malayi Pre-SET motif family protein 0.0659 0.7413 0.7638
Echinococcus multilocularis GPCR, family 2 0.0061 0.0521 0.096
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0044 0.0322 0.0592
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0103 0.0189
Brugia malayi F/Y-rich N-terminus family protein 0.0041 0.0285 0.0294
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0037 0.0236 0.0436
Loa Loa (eye worm) latrophilin receptor protein 2 0.0061 0.0521 0.0537
Schistosoma mansoni hypothetical protein 0.003 0.0162 0.0162
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0158 0.0199
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0377 0.0694
Echinococcus granulosus tissue type plasminogen activator 0.0191 0.2014 0.3712
Brugia malayi Pre-SET motif family protein 0.0095 0.0908 0.0936
Brugia malayi hypothetical protein 0.0035 0.0218 0.0225
Loa Loa (eye worm) hypothetical protein 0.0857 0.9706 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0096 0.0923 0.5365
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0487 0.5427 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Echinococcus multilocularis Chromo domain 0.0025 0.0103 0.0189
Echinococcus granulosus jumonji domain containing protein 0.0129 0.13 0.2396
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.003 0.0158 0.0199
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0047 0.036 0.0663
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Brugia malayi hypothetical protein 0.023 0.2471 0.2546
Loa Loa (eye worm) hypothetical protein 0.0069 0.0611 0.063
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0189
Echinococcus granulosus delta-like protein 1 0.0027 0.0126 0.0232
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0377 0.0388
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.003 0.0158 0.0291
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0002 0.0003
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0027 0.0126 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0653 0.0823
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0355 0.0366
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0882 0.1625
Schistosoma mansoni protein phosphatase 2C 0.003 0.0158 0.0158
Echinococcus granulosus chromobox protein 2 0.0025 0.0103 0.0189
Trichomonas vaginalis Heterochromatin protein, putative 0.0025 0.0103 0.0121
Toxoplasma gondii histone lysine methyltransferase SET1 0.0049 0.0384 0.0707
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0908 0.1673
Plasmodium falciparum glutathione reductase 0.0038 0.0251 0.0462
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.011 0.0203
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Brugia malayi MH2 domain containing protein 0.0098 0.0941 0.0969
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0082 0.0755 0.1391
Entamoeba histolytica hypothetical protein 0.0025 0.0103 0.0189
Trichomonas vaginalis hypothetical protein 0.0025 0.0103 0.0121
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0262 0.033
Mycobacterium leprae Probable lipase LipE 0.0073 0.0653 0.3583
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0053 0.0428 0.0428
Echinococcus granulosus neurogenic locus notch protein 0.0027 0.0126 0.0232
Echinococcus multilocularis tumor protein p63 0.0241 0.2594 0.478
Schistosoma mansoni hypothetical protein 0.0061 0.0521 0.0521
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0027 0.0126 0.0126
Trypanosoma brucei hypothetical protein, conserved 0.0704 0.7935 1
Onchocerca volvulus 0.0047 0.0355 0.0281
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.003 0.0162 0.0299
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0126 0.1268 0.2282
Onchocerca volvulus 0.0073 0.0653 0.0592
Brugia malayi Calcitonin receptor-like protein seb-1 0.0194 0.2051 0.2113
Schistosoma mansoni phd/f-box containing protein 0.003 0.0158 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Loa Loa (eye worm) hypothetical protein 0.0026 0.0107 0.011
Treponema pallidum fructose-bisphosphate aldolase 0.0322 0.3524 1
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0101 0.0973 0.0973
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Plasmodium vivax hypothetical protein, conserved 0.0093 0.0882 0.1463
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0126 0.1268 0.2337
Brugia malayi GCC2 and GCC3 family protein 0.0027 0.0126 0.013
Echinococcus multilocularis peregrin 0.0094 0.0898 0.1656
Toxoplasma gondii Amylo-alpha-1,6-glucosidase 0.0157 0.1618 0.2982
Schistosoma mansoni slit 0.0027 0.0126 0.0126
Trypanosoma brucei glucosidase, putative 0.0082 0.0755 0.0951
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0294 0.0348
Brugia malayi hypothetical protein 0.0025 0.0103 0.0106
Echinococcus multilocularis tissue type plasminogen activator 0.0191 0.2014 0.3712
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0027 0.0049
Echinococcus multilocularis Chromobox protein 3 0.0025 0.0103 0.0189
Echinococcus multilocularis chromobox protein 1 0.0154 0.1584 0.2919
Loa Loa (eye worm) hypothetical protein 0.004 0.0275 0.0283
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Echinococcus multilocularis glycogen debranching enzyme 0.0157 0.1618 0.2982
Echinococcus multilocularis neurogenic locus notch protein 0.0027 0.0126 0.0232
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0027 0.0049
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Brugia malayi Thioredoxin reductase 0.0038 0.0251 0.0258
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0026 0.011 0.5
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0025 0.0103 0.0189
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0194 0.2051 0.2113
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Plasmodium vivax glutathione reductase, putative 0.0038 0.0251 0.0278
Schistosoma mansoni hypothetical protein 0.0101 0.0973 0.0973
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0487 0.5427 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0158 0.0163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0191 0.0226
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.2471 0.4553
Onchocerca volvulus 0.0757 0.8545 0.8794
Loa Loa (eye worm) hypothetical protein 0.0097 0.0928 0.0956
Schistosoma mansoni alpha-glucosidase 0.0332 0.3642 0.3642
Trypanosoma brucei hypothetical protein, conserved 0.0704 0.7935 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Echinococcus multilocularis Mastin 0.0101 0.0973 0.1794
Brugia malayi Trypsin family protein 0.0101 0.0973 0.1003
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0653 0.0772
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0158 0.0199
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0377 0.0475
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0179 0.0143
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Echinococcus multilocularis lysine specific demethylase 6a 0.003 0.0158 0.0291
Echinococcus multilocularis JmjC domain containing protein 4 0.003 0.0158 0.0291
Mycobacterium ulcerans beta-lactamase 0.0073 0.0653 0.3583
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0857 0.9706 0.9706
Echinococcus granulosus transmembrane protease serine 3 0.0101 0.0973 0.1794
Onchocerca volvulus Neurogenic locus notch homolog 0.0027 0.0126 0.0043
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0377 0.0694
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0157 0.1626 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Schistosoma mansoni septate junction protein 0.0027 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0093 0.0882 0.0908
Leishmania major glycosyl hydrolase-like protein 0.0047 0.036 0.0663
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1268 0.1268
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Giardia lamblia Fructose-bisphosphate aldolase 0.0322 0.3524 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0082 0.0755 0.0892
Brugia malayi Kringle domain containing protein 0.0191 0.2014 0.2075
Schistosoma mansoni hypothetical protein 0.0191 0.2014 0.2014
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0251 0.0277
Brugia malayi Heterochromatin protein 1 0.0154 0.1584 0.1632
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0061 0.0521 0.096
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0377 0.0694
Loa Loa (eye worm) hypothetical protein 0.023 0.2471 0.2546
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0138
Echinococcus granulosus lysine specific demethylase 5A 0.0113 0.1122 0.2068
Echinococcus multilocularis enteropeptidase 0.0101 0.0973 0.1794
Onchocerca volvulus 0.0035 0.022 0.0141
Brugia malayi PHD-finger family protein 0.0032 0.0178 0.0183
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0487 0.5427 1
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0084 0.0779 0.0802
Giardia lamblia GTOR 0.0049 0.0377 0.1069
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0093 0.0881 0.0828
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0487 0.5427 0.6839
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.0973
Loa Loa (eye worm) heterochromatin protein 1 0.0154 0.1584 0.1632
Echinococcus multilocularis slit 2 protein 0.0027 0.0126 0.0232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Brugia malayi jmjC domain containing protein 0.0113 0.1122 0.1156
Leishmania major hypothetical protein, conserved 0.0073 0.0653 0.1204
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0806 0.0952
Schistosoma mansoni hypothetical protein 0.0025 0.0103 0.0103
Mycobacterium ulcerans lipase LipD 0.0073 0.0653 0.3583
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Echinococcus multilocularis glycoprotein Antigen 5 0.0101 0.0973 0.1794
Onchocerca volvulus 0.0073 0.0653 0.0592
Entamoeba histolytica hypothetical protein 0.0025 0.0103 0.0189
Echinococcus multilocularis neural cadherin 0.0027 0.0126 0.0232
Brugia malayi beta-lactamase family protein 0.0073 0.0653 0.0673
Brugia malayi chromobox protein homolog 3 0.0086 0.0806 0.083
Schistosoma mansoni cell polarity protein 0.0027 0.0126 0.0126
Mycobacterium tuberculosis Probable reductase 0.0087 0.0812 0.1383
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0653 0.107
Loa Loa (eye worm) hypothetical protein 0.0857 0.9706 1
Brugia malayi latrophilin 2 splice variant baaae 0.0133 0.1343 0.1383
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0908 0.1673
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0653 0.1204
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.011 0.0139
Echinococcus multilocularis jumonji domain containing protein 0.0129 0.13 0.2396
Trichomonas vaginalis chromobox protein, putative 0.0154 0.1584 0.1872
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0126 0.013
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0487 0.5427 0.5591
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0232 0.0428
Loa Loa (eye worm) hypothetical protein 0.0039 0.0262 0.027
Schistosoma mansoni egf-like domain protein 0.0071 0.0633 0.0633
Giardia lamblia High cysteine protein 0.0027 0.0126 0.0357
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0087 0.0812 0.1383
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Echinococcus granulosus glycogen debranching enzyme 0.0157 0.1618 0.2982
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0037 0.0236 0.0436
Echinococcus multilocularis neurogenic locus notch protein 4 0.0027 0.0126 0.0232
Toxoplasma gondii EGF family domain-containing protein 0.0027 0.0126 0.0232
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0113 0.1122 0.1122
Schistosoma mansoni hypothetical protein 0.0061 0.0521 0.0521
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0179 0.0211
Onchocerca volvulus 0.0191 0.2014 0.2006
Brugia malayi Glycosyl hydrolases family 31 protein 0.0047 0.036 0.0371
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Trichomonas vaginalis maltase-glucoamylase, putative 0.0082 0.0755 0.0892
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0908 0.0908
Trichomonas vaginalis set domain proteins, putative 0.075 0.8463 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0262 0.033
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.0755 0.0951
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Onchocerca volvulus 0.0332 0.3642 0.3698
Brugia malayi Trypsin-like protease protein 5 0.0101 0.0973 0.1003
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Brugia malayi beta-lactamase family protein 0.0073 0.0653 0.0673
Plasmodium vivax SET domain protein, putative 0.0095 0.0908 0.1513
Brugia malayi CHD4 protein 0.0026 0.0118 0.0122
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Plasmodium falciparum cysteine repeat modular protein 1 0.0191 0.2014 0.3712
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0071 0.0633 0.0653
Echinococcus granulosus notch 0.0027 0.0126 0.0232
Brugia malayi Trypsin family protein 0.0101 0.0973 0.1003
Echinococcus granulosus lysine specific demethylase 6a 0.003 0.0158 0.0291
Schistosoma mansoni hypothetical protein 0.0201 0.2134 0.2134
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0126 0.013
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0377 0.0475
Echinococcus granulosus peregrin 0.0094 0.0898 0.1656
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0487 0.5427 0.5591
Onchocerca volvulus 0.0025 0.0103 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0138
Echinococcus granulosus laminin 0.0071 0.0633 0.1167
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0083 0.0771 0.0771
Loa Loa (eye worm) hypothetical protein 0.0133 0.1343 0.1383
Echinococcus granulosus dnaJ subfamily B 0.0335 0.3678 0.6778
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0908 0.1673
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0037 0.0236 0.0436
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0093 0.0882 0.0882
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0047 0.036 0.0454
Trichomonas vaginalis esterase, putative 0.0073 0.0653 0.0772
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0653 0.107
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0061 0.0521 0.096
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0126 0.1268 0.2337
Echinococcus granulosus neural cadherin 0.0027 0.0126 0.0232
Echinococcus granulosus JmjC domain containing protein 4 0.003 0.0158 0.0291
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0262 0.0483
Echinococcus granulosus CREB binding protein 0.0083 0.0771 0.142
Echinococcus granulosus protein jagged 2 0.0027 0.0126 0.0232
Trichomonas vaginalis glycogen debranching enzyme, putative 0.0157 0.1618 0.1912
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0082 0.0755 0.0892
Echinococcus multilocularis lysosomal alpha glucosidase 0.0366 0.4037 0.7439
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0061 0.0521 0.096
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0303 0.3314 0.6107
Brugia malayi TAZ zinc finger family protein 0.0083 0.0771 0.0794
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0191 0.2014 0.2075
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0025 0.0103 0.0189
Echinococcus multilocularis PHD finger protein rhinoceros 0.0093 0.0882 0.1625
Echinococcus multilocularis neurogenic locus protein delta 0.0027 0.0126 0.0232
Onchocerca volvulus 0.0092 0.0871 0.0818
Loa Loa (eye worm) jmjC domain-containing protein 0.0191 0.202 0.2081
Onchocerca volvulus 0.0073 0.0653 0.0592
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0047 0.036 0.0454
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0047 0.036 0.0287
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0158 0.0163
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0653 0.0772
Giardia lamblia 4-alpha-glucanotransferase, amylo-alpha-1,6-glucosidase 0.0157 0.1618 0.4593
Plasmodium vivax JmjC domain containing protein 0.003 0.0158 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Giardia lamblia PHD finger protein 15 0.0093 0.0882 0.2502
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0096 0.0923 0.1603
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Leishmania major hypothetical protein, conserved 0.0191 0.2014 0.3712
Loa Loa (eye worm) CBP-B 0.0058 0.0478 0.0492
Echinococcus granulosus neurogenic locus protein delta 0.0027 0.0126 0.0232
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0194 0.2051 0.2113
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0653 0.107
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Leishmania major hypothetical protein, conserved 0.003 0.0158 0.0291
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.64 uM Inhibition of rat isomaltase ChEMBL. 18258441
IC50 (binding) = 0.64 uM Inhibition of rat isomaltase ChEMBL. 18258441
IC50 (binding) = 4.4 uM Inhibition of human lysosomal alpha glucosidase ChEMBL. 18258441
IC50 (binding) = 5.2 uM Inhibition of rat sucrase ChEMBL. 18258441
IC50 (binding) = 5.2 uM Inhibition of rat sucrase ChEMBL. 18258441
IC50 (binding) = 8.6 uM Inhibition of rice alpha-glucosidase ChEMBL. 18258441
IC50 (binding) = 10 uM Inhibition of rat intestinal maltase ChEMBL. 18258441
IC50 (binding) = 10 uM Inhibition of rat intestinal maltase ChEMBL. 18258441
IC50 (binding) = 16 uM Inhibition of amylo-1,6-glucosidase (unknown origin) ChEMBL. 18258441
IC50 (binding) = 16 uM Inhibition of amylo-1,6-glucosidase (unknown origin) ChEMBL. 18258441
IC50 (binding) = 900 uM Inhibition of yeast alpha-glucosidase ChEMBL. 18258441
Inhibition (binding) = 30 % Inhibition of maltase in human Caco2 cell membrane at 1 uM ChEMBL. 18258441
Inhibition (binding) < 50 % Inhibition of rabbit muscle glycogen phosphorylase b at 400 uM ChEMBL. 18258441

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.