Detailed information for compound 51500

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 430.52 | Formula: C17H19KN4O5S
  • H donors: 1 H acceptors: 6 LogP: 1.73 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCn1c2[nH]c(nc2c(=O)n(c1=O)CCC)c1ccc(cc1)S(=O)(=O)[O-].[K+]
  • InChi: 1S/C17H20N4O5S.K/c1-3-9-20-15-13(16(22)21(10-4-2)17(20)23)18-14(19-15)11-5-7-12(8-6-11)27(24,25)26;/h5-8H,3-4,9-10H2,1-2H3,(H,18,19)(H,24,25,26);/q;+1/p-1
  • InChiKey: SWTMHNGSYKBYJL-UHFFFAOYSA-M  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens adenosine A3 receptor Starlite/ChEMBL References
Homo sapiens adenosine A2b receptor Starlite/ChEMBL References
Rattus norvegicus Adenosine A2a receptor Starlite/ChEMBL References
Rattus norvegicus Adenosine A1 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni biogenic amine (5HT) receptor Adenosine A2a receptor   410 aa 399 aa 28.1 %
Onchocerca volvulus Adenosine A1 receptor   326 aa 306 aa 21.2 %
Onchocerca volvulus Ubiquinol-cytochrome-c reductase complex assembly factor 1 homolog Adenosine A1 receptor   326 aa 286 aa 22.7 %
Echinococcus granulosus allatostatin A receptor Adenosine A2a receptor   410 aa 368 aa 22.6 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Adenosine A2a receptor   410 aa 366 aa 25.4 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Adenosine A2a receptor   410 aa 352 aa 23.6 %
Brugia malayi hypothetical protein Adenosine A1 receptor   326 aa 305 aa 21.0 %
Onchocerca volvulus Adenosine A2a receptor   410 aa 337 aa 23.1 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Adenosine A2a receptor   410 aa 342 aa 23.1 %
Onchocerca volvulus Adenosine A2a receptor   410 aa 356 aa 23.9 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Adenosine A2a receptor   410 aa 346 aa 28.3 %
Schistosoma mansoni neuropeptide receptor Adenosine A1 receptor   326 aa 311 aa 21.2 %
Onchocerca volvulus Mitochondrial inner membrane protein homolog Adenosine A2a receptor   410 aa 340 aa 27.9 %
Schistosoma japonicum ko:K04134 cholinergic receptor, invertebrate, putative Adenosine A1 receptor   326 aa 317 aa 24.6 %
Schistosoma japonicum Alpha-1A adrenergic receptor, putative Adenosine A1 receptor   326 aa 295 aa 28.1 %
Echinococcus granulosus thyrotropin releasing hormone receptor Adenosine A2a receptor   410 aa 342 aa 23.1 %
Loa Loa (eye worm) neuropeptide F receptor Adenosine A1 receptor   326 aa 316 aa 19.9 %
Schistosoma japonicum 5-hydroxytryptamine receptor 4, putative Adenosine A1 receptor   326 aa 286 aa 26.9 %
Onchocerca volvulus Adenosine A1 receptor   326 aa 323 aa 20.7 %
Schistosoma mansoni neuropeptide receptor Adenosine A1 receptor   326 aa 274 aa 22.6 %
Schistosoma mansoni peptide (allatostatin)-like receptor Adenosine A1 receptor   326 aa 327 aa 24.8 %
Echinococcus granulosus neuropeptide receptor Adenosine A1 receptor   326 aa 299 aa 22.4 %
Loa Loa (eye worm) hypothetical protein Adenosine A1 receptor   326 aa 300 aa 24.3 %
Echinococcus multilocularis neuropeptide receptor Adenosine A1 receptor   326 aa 299 aa 22.4 %
Schistosoma mansoni dro/myosuppressin receptor Adenosine A1 receptor   326 aa 326 aa 22.1 %
Echinococcus multilocularis allatostatin A receptor Adenosine A2a receptor   410 aa 372 aa 22.8 %
Onchocerca volvulus Adenosine A1 receptor   326 aa 304 aa 21.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear receptor NHR-67 0.0033 0.0349 0.0488
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0007 0.0015 0.0024
Onchocerca volvulus 0.0045 0.0492 0.1187
Leishmania major hypothetical protein, conserved 0.0007 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0079 0.0934 0.1313
Brugia malayi small heat shock protein 0.0558 0.71 1
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0243 0.032
Echinococcus multilocularis protein C ets 2 0.002 0.018 0.0178
Mycobacterium ulcerans short-chain type oxidoreductase 0.0007 0.0015 0.0025
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0005 0.0012
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0378 0.0502
Echinococcus granulosus Chromo domain 0.0011 0.0064 0.0072
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0071 0.083 0.0974
Mycobacterium ulcerans carboxylesterase, LipT 0.0045 0.0492 0.1259
Echinococcus multilocularis BRK domain containing protein 0.0011 0.0063 0.0061
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0074 0.0101
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0012 0.0074 0.0084
Loa Loa (eye worm) hypothetical protein 0.0015 0.0117 0.0162
Onchocerca volvulus Protein ultraspiracle homolog 0.0071 0.083 0.2004
Schistosoma mansoni hypothetical protein 0.0297 0.3746 0.4406
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.2859 0.2857
Brugia malayi Dopamine receptor protein 1 0.0011 0.0067 0.0091
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0098 0.0134
Echinococcus granulosus snurportin 1 0.0297 0.3746 0.4406
Leishmania major quinonoid dihydropteridine reductase 0.0007 0.0015 0.0013
Echinococcus granulosus Ankyrin 0.0014 0.0099 0.0114
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0519 0.0727
Brugia malayi larval opioid receptor 0.0011 0.0067 0.0091
Brugia malayi Dopamine receptor 0.0011 0.0067 0.0091
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0025
Echinococcus granulosus glycine receptor subunit beta 0.0012 0.0074 0.0084
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0012 0.0074 0.0072
Echinococcus multilocularis GPCR, family 2 0.003 0.0311 0.0309
Echinococcus granulosus g-protein coupled receptor 0.0011 0.0067 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0067 0.0076
Schistosoma mansoni transcription factor LCR-F1 0.0106 0.1277 0.15
Schistosoma mansoni biogenic amine (5HT) receptor 0.0011 0.0067 0.0076
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0007 0.0015 0.0013
Brugia malayi Cell death protein 3 precursor 0.0083 0.0981 0.1379
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0012 0.0074 0.0101
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0084
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0012 0.0074 0.0101
Schistosoma mansoni hypothetical protein 0.0011 0.0067 0.0076
Brugia malayi excitatory GABA receptor EXP-1A 0.0012 0.0074 0.0101
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0378 0.0886
Brugia malayi Melatonin receptor type 1A 0.0011 0.0067 0.0091
Trypanosoma cruzi Double RNA binding domain protein 3 0.0009 0.0034 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Trypanosoma brucei DNA polymerase eta, putative 0.0014 0.0099 0.0126
Schistosoma mansoni steroid dehydrogenase 0.0007 0.0015 0.0015
Brugia malayi neuropeptide F receptor 0.0011 0.0067 0.0091
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0349 0.0838
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0071 0.083 0.1166
Schistosoma mansoni coup transcription factor 0.0071 0.083 0.0974
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0037 0.04 0.0468
Loa Loa (eye worm) carboxylesterase 0.0045 0.0492 0.069
Schistosoma mansoni Smad4 0.0016 0.0121 0.014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0099 0.0136
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0007 0.0015 0.0013
Brugia malayi hypothetical protein 0.0064 0.0739 0.1037
Onchocerca volvulus 0.0009 0.0034 0.0076
Echinococcus granulosus allatostatin A receptor 0.0011 0.0067 0.0076
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0012 0.0074 0.0101
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0444 0.0442
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Schistosoma mansoni flap endonuclease-1 0.0023 0.0212 0.0246
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0115 0.0159
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0012 0.0071 0.0584
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0099 0.0114
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0011 0.0067 0.0064
Brugia malayi Carboxylesterase family protein 0.0264 0.3313 0.4665
Echinococcus multilocularis FTZ F1 alpha 0.0071 0.083 0.0828
Leishmania major quinonoid dihydropteridine reductase 0.0007 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0011 0.0067 0.0091
Loa Loa (eye worm) hypothetical protein 0.0089 0.1058 0.1487
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0378 0.0502
Schistosoma mansoni neuropeptide F-like receptor 0.0011 0.0067 0.0076
Brugia malayi GnHR receptor homolog 0.0011 0.0067 0.0091
Entamoeba histolytica hypothetical protein 0.0106 0.1277 0.3006
Leishmania major short chain dehydrogenase, putative 0.0007 0.0015 0.0013
Schistosoma mansoni ran 0.0021 0.0183 0.0212
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0214 0.028
Schistosoma mansoni opsin-like receptor 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Loa Loa (eye worm) hypothetical protein 0.0045 0.0492 0.069
Brugia malayi MH2 domain containing protein 0.0016 0.0121 0.0167
Loa Loa (eye worm) hypothetical protein 0.0023 0.0214 0.0298
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0005 0.0003
Mycobacterium ulcerans dehydrogenase 0.0007 0.0015 0.0025
Trypanosoma brucei short-chain dehydrogenase, putative 0.0007 0.0015 0.0013
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0347 0.0461
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0164 0.0258
Onchocerca volvulus Neuropeptide F receptor homolog 0.0011 0.0067 0.0156
Echinococcus multilocularis neuropeptide s receptor 0.0011 0.0067 0.0064
Schistosoma mansoni jun-related protein 0.0066 0.0767 0.09
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Trypanosoma brucei short-chain dehydrogenase, putative 0.0007 0.0015 0.0013
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0007 0.0015 0.0024
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0469 1
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0098 0.0112
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0115 0.0159
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0011 0.0067 0.0064
Trypanosoma cruzi metacaspase, putative 0.0043 0.0469 0.0624
Onchocerca volvulus 0.0011 0.0067 0.0156
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0011 0.0067 0.0091
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0214 0.0498
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0115 0.0295
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0067 0.0076
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0099 0.0114
Brugia malayi hypothetical protein 0.0011 0.0067 0.0091
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0007 0.0015 0.0024
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0067 0.0076
Schistosoma mansoni amine GPCR 0.0011 0.0067 0.0076
Giardia lamblia Hypothetical protein 0.0089 0.1058 0.2468
Brugia malayi nuclear receptor NHR-88 0.0033 0.0349 0.0488
Loa Loa (eye worm) ets-domain-containing protein 0.002 0.018 0.025
Schistosoma mansoni acetylcholinesterase 0.0045 0.0492 0.0577
Brugia malayi BRM protein 0.0065 0.0754 0.1059
Loa Loa (eye worm) hypothetical protein 0.0014 0.0099 0.0136
Brugia malayi MH1 domain containing protein 0.0009 0.0031 0.004
Onchocerca volvulus 0.0007 0.0015 0.003
Schistosoma mansoni hypothetical protein 0.0013 0.0084 0.0096
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0007 0.0015 0.0036
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0059 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.04 0.056
Trypanosoma brucei short-chain dehydrogenase, putative 0.0007 0.0015 0.0013
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0183 0.0239
Schistosoma mansoni hypothetical protein 0.0066 0.0767 0.09
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0007 0.0015 0.0013
Plasmodium vivax DEAD/DEAH helicase, putative 0.001 0.0049 0.0941
Echinococcus multilocularis Smad4 0.0016 0.0121 0.0119
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0121 0.0119
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0005 0.0012
Schistosoma mansoni hypothetical protein 0.0066 0.0766 0.0899
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0007 0.0015 0.0013
Mycobacterium ulcerans hypothetical protein 0.0018 0.0154 0.0384
Schistosoma mansoni biogenic amine receptor 0.0011 0.0067 0.0076
Onchocerca volvulus 0.0011 0.0067 0.0156
Echinococcus multilocularis serotonin receptor 0.0011 0.0067 0.0064
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0029 0.0038
Schistosoma mansoni hypothetical protein 0.005 0.0562 0.0659
Schistosoma mansoni hypothetical protein 0.0011 0.0059 0.0067
Echinococcus multilocularis neuropeptide receptor 0.0011 0.0067 0.0064
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0005 0.0004
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0469 0.0739
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0007 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0117 0.0162
Leishmania major short chain dehydrogenase/reductase, putative 0.0007 0.0015 0.0013
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0115 0.0148
Echinococcus multilocularis SPRY domain containing protein 0.0015 0.0117 0.0115
Toxoplasma gondii oxidoreductase, putative 0.0007 0.0015 0.0084
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0007 0.0015 0.0024
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0243 0.024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0469 0.0739
Entamoeba histolytica hypothetical protein 0.0007 0.0015 0.003
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0378 0.0963
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.4359 0.6875
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0071 0.083 0.1166
Loa Loa (eye worm) oxidoreductase 0.0007 0.0015 0.0018
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0099 0.0096
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0164 0.0258
Echinococcus multilocularis serotonin receptor 0.0011 0.0067 0.0064
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.083 0.0828
Brugia malayi Flap endonuclease-1 0.0025 0.0243 0.0339
Schistosoma mansoni nAChR subunit 0.0012 0.0074 0.0084
Echinococcus multilocularis ETS transcription factor Elf 5 0.002 0.018 0.0178
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0081 0.0963 0.1131
Brugia malayi putative neuropeptide receptor NPR1 0.0011 0.0067 0.0091
Onchocerca volvulus 0.0047 0.0519 0.125
Schistosoma mansoni ran 0.0021 0.0183 0.0212
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0243 0.032
Mycobacterium tuberculosis Probable oxidoreductase 0.0007 0.0015 0.0036
Trichomonas vaginalis replication factor C large subunit, putative 0.0019 0.0164 0.0258
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.021 0.0275
Echinococcus multilocularis ETS transcription factor Elf 2 0.002 0.018 0.0178
Schistosoma mansoni patched 1 0.0041 0.0444 0.052
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0011 0.0067 0.0091
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0276 0.3473 0.4671
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0011 0.0067 0.0064
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0071 0.083 0.0828
Trypanosoma cruzi hypothetical protein, conserved 0.0007 0.0015 0.0013
Echinococcus granulosus dna polymerase eta 0.0014 0.0099 0.0114
Echinococcus granulosus dna polymerase kappa 0.004 0.0429 0.0503
Leishmania major hypothetical protein, conserved 0.0024 0.0232 0.0306
Loa Loa (eye worm) hypothetical protein 0.0045 0.0492 0.069
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0011 0.0067 0.0076
Schistosoma mansoni hypothetical protein 0.002 0.018 0.0209
Mycobacterium tuberculosis Conserved hypothetical protein 0.0307 0.3874 1
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0084
Leishmania major mitochondrial DNA polymerase beta 0.0584 0.7428 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0115 0.2371
Echinococcus granulosus BRK domain containing protein 0.0011 0.0063 0.0072
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0007 0.0015 0.0013
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0011 0.0067 0.0156
Onchocerca volvulus 0.0033 0.0349 0.0838
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0214 0.0538
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0036
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0153 0.0198
Echinococcus multilocularis musashi 0.0052 0.0589 0.0587
Loa Loa (eye worm) hypothetical protein 0.0289 0.3633 0.5116
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0139 0.0357
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0007 0.0015 0.0013
Echinococcus multilocularis mothers against decapentaplegic 6 0.0007 0.0009 0.0007
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0278 0.0388
Echinococcus multilocularis BRK domain containing protein 0.0011 0.0063 0.0061
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0074 0.0101
Schistosoma mansoni neuropeptide receptor 0.0011 0.0067 0.0076
Onchocerca volvulus 0.0012 0.0074 0.0173
Plasmodium vivax replication factor C subunit 1, putative 0.0019 0.0164 0.3415
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0011 0.0067 0.0064
Brugia malayi G-protein coupled receptor 0.0011 0.0067 0.0091
Schistosoma mansoni steroid dehydrogenase 0.0007 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0067 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0429 0.0571
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0277 0.0366
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0584 0.7428 1
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0007 0.0015 0.0084
Trypanosoma brucei short-chain dehydrogenase, putative 0.0007 0.0015 0.0013
Echinococcus granulosus neuropeptide receptor 0.0011 0.0067 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.0007 0.0015 0.0013
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0153 0.0198
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0007 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0083 0.0981 0.1379
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.068 0.0678
Echinococcus granulosus tumor protein p63 0.0326 0.412 0.4846
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0378 0.0596
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0098 0.0112
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0011 0.0067 0.0064
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0164 0.1407
Schistosoma mansoni hypothetical protein 0.003 0.0311 0.0363
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Echinococcus granulosus nAChR subunit 0.0012 0.0074 0.0084
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0378 0.0502
Schistosoma mansoni hypothetical protein 0.003 0.0311 0.0363
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0082 0.0975 0.1306
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Schistosoma mansoni nuclear hormone receptor 0.0071 0.083 0.0974
Schistosoma mansoni nuclear receptor 0.0033 0.0349 0.0408
Plasmodium vivax steroid dehydrogenase, putative 0.0007 0.0015 0.0205
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0005 0.0004
Schistosoma mansoni topbp1 0.0019 0.0164 0.019
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0429 0.0571
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0164 0.1407
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Mycobacterium tuberculosis Probable oxidoreductase 0.0007 0.0015 0.0036
Schistosoma mansoni myosin xvIII 0.0011 0.0067 0.0076
Brugia malayi MH1 domain containing protein 0.0016 0.0121 0.0167
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0183 0.3826
Schistosoma mansoni thyroid hormone receptor 0.0071 0.083 0.0974
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0115 0.0113
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.068 0.1753
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0429 0.0571
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0007 0.0015 0.0025
Toxoplasma gondii RNA recognition motif-containing protein 0.0012 0.0073 0.0597
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0243 0.032
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0007 0.0015 0.0015
Onchocerca volvulus 0.0007 0.0015 0.003
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0429 0.1096
Schistosoma mansoni nAChR subunit 0.0012 0.0074 0.0084
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Echinococcus multilocularis dro:myosuppressin receptor 0.0011 0.0067 0.0064
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Mycobacterium tuberculosis Conserved hypothetical protein 0.0014 0.0099 0.0253
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0305 0.0404
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0276 0.3473 0.4671
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0232 0.4895
Loa Loa (eye worm) ACC-1 protein 0.0012 0.0074 0.0101
Onchocerca volvulus 0.0033 0.0349 0.0838
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0011 0.0067 0.0064
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Schistosoma mansoni hypothetical protein 0.0039 0.0425 0.0498
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0153 0.3178
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0007 0.0015 0.0013
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0074 0.0101
Mycobacterium tuberculosis Probable oxidoreductase 0.0007 0.0015 0.0036
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Onchocerca volvulus 0.0048 0.0534 0.1287
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.083 0.1166
Brugia malayi Importin beta-1 subunit 0.0028 0.0277 0.0387
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0469 0.0739
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0064 0.0086
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0005 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0214 0.0538
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0005 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.083 0.1166
Echinococcus granulosus tachykinin peptides receptor 99D 0.0011 0.0067 0.0076
Trypanosoma cruzi DNA repair and recombination protein RAD54, putative 0.0015 0.0117 0.0151
Echinococcus multilocularis neuropeptide receptor 0.0011 0.0067 0.0064
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0059 0.0067
Brugia malayi orphan nuclear receptor NR2E1 0.0033 0.0349 0.0488
Echinococcus multilocularis Regulator of differentiation 1 0.0012 0.0073 0.007
Onchocerca volvulus 0.0011 0.0067 0.0156
Leishmania major hypothetical protein, conserved 0.0007 0.0015 0.0013
Schistosoma mansoni lamin 0.0052 0.0589 0.0691
Brugia malayi MH2 domain containing protein 0.0007 0.0009 0.001
Echinococcus granulosus nibrin 0.0019 0.0164 0.019
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Brugia malayi putative neuropeptide receptor 0.0011 0.0067 0.0091
Brugia malayi MH2 domain containing protein 0.0016 0.0121 0.0167
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Echinococcus granulosus hypothetical protein 0.0007 0.0015 0.0015
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0005 0.0012
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Echinococcus granulosus neuroligin 0.0045 0.0492 0.0577
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0277 0.0275
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0305 0.0404
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Schistosoma mansoni thyroid hormone receptor 0.0071 0.083 0.0974
Brugia malayi AKH receptor 0.0011 0.0067 0.0091
Leishmania major dehydrogenase-like protein 0.0007 0.0015 0.0013
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0007 0.0015 0.0036
Brugia malayi G protein-coupled receptor 0.0011 0.0067 0.0091
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0005 0.0012
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0084
Loa Loa (eye worm) oxidoreductase 0.0007 0.0015 0.0018
Entamoeba histolytica short chain dehydrogenase family protein 0.0007 0.0015 0.003
Echinococcus granulosus Smad4 0.0016 0.0121 0.014
Brugia malayi Protein kinase domain containing protein 0.0014 0.0098 0.0134
Entamoeba histolytica CAAX prenyl protease family 0.0089 0.1058 0.2491
Schistosoma mansoni zinc finger protein 0.0033 0.0349 0.0408
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Entamoeba histolytica hypothetical protein 0.0106 0.1277 0.3006
Mycobacterium ulcerans short-chain dehydrogenase 0.0007 0.0015 0.0025
Schistosoma mansoni hypothetical protein 0.002 0.018 0.0209
Brugia malayi hypothetical protein 0.0011 0.0067 0.0091
Chlamydia trachomatis DNA ligase 0.0019 0.0164 1
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0429 0.0571
Brugia malayi Intermediate filament tail domain containing protein 0.0052 0.0589 0.0827
Loa Loa (eye worm) hypothetical protein 0.0024 0.023 0.0321
Echinococcus granulosus smad 0.0016 0.0121 0.014
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0071 0.083 0.0974
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0007 0.0015 0.0036
Brugia malayi tailless protein 0.0033 0.0349 0.0488
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0214 0.0538
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0037 0.04 0.056
Echinococcus granulosus g protein coupled receptor 0.0011 0.0067 0.0076
Schistosoma mansoni amine GPCR 0.0011 0.0067 0.0076
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.033 1
Plasmodium vivax hypothetical protein, conserved 0.0007 0.0015 0.0205
Echinococcus granulosus flap endonuclease 1 0.0025 0.0243 0.0283
Schistosoma mansoni neuropeptide receptor 0.0011 0.0067 0.0076
Loa Loa (eye worm) nuclear factor I 0.0009 0.0031 0.004
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0834 0.0832
Chlamydia trachomatis hypothetical protein 0.0018 0.0154 0.604
Brugia malayi hypothetical protein 0.0012 0.0073 0.0099
Echinococcus multilocularis neuropeptide receptor A26 0.0011 0.0067 0.0064
Brugia malayi Carboxylesterase family protein 0.0045 0.0492 0.069
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0011 0.0067 0.0091
Echinococcus granulosus sex peptide receptor 0.0011 0.0067 0.0076
Trypanosoma brucei metacaspase 5, putative 0.0043 0.0469 0.0624
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0121 0.014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0025
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0096 0.1158 0.1629
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0007 0.0015 0.003
Onchocerca volvulus Huntingtin homolog 0.0118 0.1442 0.3486
Onchocerca volvulus 0.0011 0.0067 0.0156
Schistosoma mansoni nAChR subunit 0.0012 0.0074 0.0084
Schistosoma mansoni nAChR subunit 0.0012 0.0074 0.0084
Leishmania major DNA repair and recombination protein RAD54, putative 0.0015 0.0117 0.0151
Schistosoma mansoni hypothetical protein 0.0011 0.0064 0.0072
Echinococcus granulosus jun protein 0.0081 0.0963 0.1131
Echinococcus granulosus tm gpcr rhodopsin 0.0011 0.0067 0.0076
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0007 0.0015 0.0015
Brugia malayi Ets-domain containing protein 0.002 0.018 0.025
Schistosoma mansoni hypothetical protein 0.0327 0.4132 0.4861
Echinococcus multilocularis G-protein coupled receptor, putative 0.0011 0.0067 0.0064
Echinococcus granulosus mothers against decapentaplegic 6 0.0007 0.0009 0.0008
Schistosoma mansoni steroid dehydrogenase 0.0007 0.0015 0.0015
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0012 0.0074 0.0084
Loa Loa (eye worm) hypothetical protein 0.0071 0.083 0.1166
Echinococcus granulosus caspase 2 0.0083 0.0981 0.1152
Echinococcus multilocularis dna repair and recombination protein rad54 0.0015 0.0117 0.0115
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Trypanosoma brucei Double RNA-binding domain containing protein 4 0.0012 0.0073 0.009
Mycobacterium tuberculosis Carboxylesterase LipT 0.0045 0.0492 0.1269
Brugia malayi Dehydrogenases, short chain protein 2 0.0007 0.0015 0.0018
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0071 0.083 0.0974
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.083 0.1166
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0071 0.083 0.0974
Schistosoma mansoni amine GPCR 0.0011 0.0067 0.0076
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0067 0.0076
Schistosoma mansoni ap endonuclease 0.0018 0.0153 0.0177
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0005 0.0012
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0007 0.0015 0.0292
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0012 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0011 0.0067 0.0064
Loa Loa (eye worm) hypothetical protein 0.0019 0.0164 0.0227
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0469 0.0739
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0469 0.4121
Brugia malayi Ets-domain containing protein 0.014 0.1719 0.2419
Trichomonas vaginalis glucosylceramidase, putative 0.0327 0.4132 0.6517
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.1143 0.1141
Loa Loa (eye worm) hypothetical protein 0.0045 0.0492 0.069
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.004
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0011 0.0067 0.0076
Schistosoma mansoni nuclear receptor nhr-48 0.0033 0.0349 0.0408
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Entamoeba histolytica CAAX amino terminal protease family 0.0018 0.0154 0.0358
Onchocerca volvulus 0.0011 0.0067 0.0156
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0099 0.0114
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0012 0.0074 0.0084
Brugia malayi nuclear receptor NHR-67 0.0033 0.0349 0.0488
Toxoplasma gondii CAAX amino terminal protease family protein 0.0018 0.0154 0.1321
Brugia malayi hypothetical protein 0.004 0.0431 0.0604
Mycobacterium tuberculosis Possible oxidoreductase 0.0007 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0025
Leishmania major quinonoid dihydropteridine reductase 0.0007 0.0015 0.0013
Loa Loa (eye worm) BRM protein 0.0041 0.0452 0.0634
Onchocerca volvulus 0.0007 0.0015 0.003
Echinococcus multilocularis acetylcholinesterase 0.0264 0.3313 0.3312
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Brugia malayi hypothetical protein 0.0011 0.0067 0.0091
Echinococcus multilocularis BRK domain containing protein 0.0011 0.0063 0.0061
Echinococcus granulosus g protein coupled receptor 0.0011 0.0067 0.0076
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0012 0.0074 0.0072
Loa Loa (eye worm) dehydrogenase 0.0007 0.0015 0.0018
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0115 0.0148
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0007 0.0015 0.0015
Plasmodium falciparum DEAD/DEAH box helicase, putative 0.001 0.0049 0.0941
Plasmodium falciparum importin beta, putative 0.0028 0.0277 0.5868
Plasmodium falciparum steroid dehydrogenase, putative 0.0007 0.0015 0.0205
Echinococcus multilocularis muscleblind protein 1 0.0289 0.3633 0.3632
Echinococcus multilocularis ETS transcription factor Elf 1 0.002 0.018 0.0178
Schistosoma mansoni amine GPCR 0.0011 0.0067 0.0076
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0007 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0067 0.0076
Brugia malayi ORL1-like opioid receptor 0.0011 0.0067 0.0091
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Echinococcus multilocularis fmrfamide receptor 0.0011 0.0067 0.0064
Toxoplasma gondii hypothetical protein 0.0094 0.113 1
Treponema pallidum DNA ligase (lig) 0.0019 0.0164 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0036
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0019 0.0164 0.0409
Entamoeba histolytica hypothetical protein 0.0096 0.1149 0.2704
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0164 0.0213
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0007 0.0015 0.0015
Trypanosoma cruzi short chain dehydrogenase, putative 0.0007 0.0015 0.0013
Echinococcus multilocularis 0.0015 0.0117 0.0115
Loa Loa (eye worm) helicase DNA-binding protein 0.0011 0.0063 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0429 0.0571
Loa Loa (eye worm) hypothetical protein 0.0264 0.3313 0.4665
Leishmania major hypothetical protein, conserved 0.0007 0.0015 0.0013
Echinococcus multilocularis snurportin 1 0.0297 0.3746 0.3744
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0469 0.0739
Plasmodium falciparum replication factor C subunit 1, putative 0.0019 0.0164 0.3415
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0007 0.0015 0.0024
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0011 0.0067 0.0064
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0499 0.634 0.893
Leishmania major DNA polymerase eta, putative 0.0014 0.0099 0.0126
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0378 0.0596
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0.0067 0.0076
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0276 0.0385
Echinococcus multilocularis retinol dehydrogenase 13 0.0007 0.0015 0.0013
Schistosoma mansoni hypothetical protein 0.0039 0.0425 0.0498
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0349 0.0408
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0444 0.0622
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.0074 0.0084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0067 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0071 0.083 0.1166
Loa Loa (eye worm) hypothetical protein 0.0118 0.1442 0.2028
Mycobacterium ulcerans dehydrogenase/reductase 0.0007 0.0015 0.0025
Schistosoma mansoni hypothetical protein 0.0011 0.0067 0.0076
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Echinococcus multilocularis g protein coupled receptor 0.0011 0.0067 0.0064
Brugia malayi recombination factor GdRad54 0.0015 0.0117 0.0162
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0008 0.0005
Echinococcus granulosus tm gpcr rhodopsin 0.0011 0.0067 0.0076
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0007 0.0015 0.0036
Giardia lamblia Replication factor C, subunit 1 0.0019 0.0164 0.0352
Echinococcus granulosus dnaJ subfamily B 0.0395 0.5004 0.5887
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Echinococcus granulosus carbonyl reductase 1 0.0007 0.0015 0.0015
Echinococcus granulosus fmrfamide receptor 0.0011 0.0067 0.0076
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0007 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.023 0.0321
Echinococcus multilocularis apoptotic protease activating factor 1 0.004 0.0431 0.0429
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0098 0.0095
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0139 0.2885
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0098 0.0112
Echinococcus granulosus retinol dehydrogenase 11 0.0007 0.0015 0.0015
Echinococcus granulosus SPRY domain containing protein 0.0015 0.0117 0.0135
Echinococcus multilocularis SPRY domain containing protein 0.0015 0.0117 0.0115
Onchocerca volvulus 0.0011 0.0067 0.0156
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0214 0.0538
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0164 0.019
Echinococcus granulosus importin subunit beta 1 0.0028 0.0277 0.0324
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0018 0.0154 0.0395
Loa Loa (eye worm) hypothetical protein 0.0015 0.0117 0.0162
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0115 0.0977
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0037 0.04 0.0468
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0082 0.0975 0.1306
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0096 0.1158 0.1629
Echinococcus granulosus neuropeptide Y receptor 0.0011 0.0067 0.0076
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.083 0.0974
Loa Loa (eye worm) hypothetical protein 0.0009 0.0034 0.0044
Schistosoma mansoni cpg binding protein 0.0029 0.0296 0.0346
Loa Loa (eye worm) TYRA-2 protein 0.0011 0.0067 0.0091
Brugia malayi Retinol dehydrogenase 12 0.0007 0.0015 0.0018
Echinococcus granulosus carboxylesterase 5A 0.0264 0.3313 0.3897
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0074 0.0084
Echinococcus granulosus nuclear receptor nhr 48 0.0033 0.0349 0.0408
Loa Loa (eye worm) Smad1 0.0016 0.0121 0.0167
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.068 0.0955
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0429 0.0571
Loa Loa (eye worm) oxidoreductase 0.0007 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.003 0.0305 0.0427
Loa Loa (eye worm) hypothetical protein 0.012 0.1458 0.2051
Loa Loa (eye worm) dehydrogenase 0.0007 0.0015 0.0018
Leishmania major hypothetical protein, conserved 0.0007 0.0015 0.0013
Schistosoma mansoni carbonyl reductase 0.0007 0.0015 0.0015
Brugia malayi Serotonin receptor 0.0011 0.0067 0.0091
Trypanosoma brucei unspecified product 0.0033 0.0347 0.0461
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0469 0.0739
Echinococcus multilocularis nibrin 0.0019 0.0164 0.0161
Brugia malayi hypothetical protein 0.0011 0.0067 0.0091
Schistosoma mansoni hypothetical protein 0.004 0.0431 0.0505
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Leishmania major 3-keto-dihydrosphingosine reductase 0.0007 0.0015 0.0013
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0153 0.0392
Echinococcus multilocularis neuropeptides capa receptor 0.0011 0.0067 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0327 0.4132 0.6517
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0469 0.0739
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0444 0.052
Mycobacterium ulcerans short-chain dehydrogenase 0.0007 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0492 0.069
Echinococcus multilocularis somatostatin receptor 0.0011 0.0067 0.0064
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0071 0.083 0.0974
Brugia malayi Cation transporter family protein 0.0012 0.0074 0.0101
Loa Loa (eye worm) hypothetical protein 0.0023 0.0214 0.0298
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0074 0.0101
Brugia malayi Latrophilin receptor protein 2 0.003 0.0311 0.0435
Trichomonas vaginalis ran, putative 0.0021 0.0183 0.0288
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Onchocerca volvulus 0.0045 0.0492 0.1187
Echinococcus granulosus orexin receptor type 2 0.0011 0.0067 0.0076
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0115 0.0148
Onchocerca volvulus 0.0011 0.0067 0.0156
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0012 0.0074 0.0084
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0007 0.0015 0.0025
Schistosoma mansoni lamin 0.0052 0.0589 0.0691
Schistosoma mansoni cpg binding protein 0.0028 0.0276 0.0322
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0469 0.0739
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0214 0.0549
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0164 0.019
Echinococcus multilocularis mothers against decapentaplegic 2 0.0007 0.0009 0.0007
Trypanosoma brucei metacaspase MCA3 0.0043 0.0469 0.0624
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0011 0.0057 0.0456
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.1668 0.1666
Mycobacterium ulcerans hypothetical protein 0.0018 0.0154 0.0384
Schistosoma mansoni neuropeptide F-like receptor 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0019 0.0164 0.0227
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0007 0.0015 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0499 0.634 1
Loa Loa (eye worm) ACC-1 protein 0.0012 0.0074 0.0101
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0005 0.0012
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0214 0.028
Schistosoma mansoni nAChR subunit 0.0012 0.0074 0.0084
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0011 0.0067 0.0076
Echinococcus multilocularis acetylcholinesterase 0.0264 0.3313 0.3312
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0181 0.0236
Echinococcus granulosus Regulator of differentiation 1 0.0012 0.0073 0.0083
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.068 0.0798
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0012 0.0074 0.0084
Brugia malayi Dopamine receptor protein 2 0.0011 0.0067 0.0091
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0183 0.0239
Echinococcus multilocularis carbonyl reductase 1 0.0007 0.0015 0.0013
Onchocerca volvulus 0.0011 0.0067 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0469 0.0739
Brugia malayi sulfakinin receptor protein 0.0011 0.0067 0.0091
Trichomonas vaginalis glucosylceramidase, putative 0.0499 0.634 1
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0243 0.5119
Loa Loa (eye worm) hypothetical protein 0.002 0.018 0.025
Onchocerca volvulus 0.0012 0.0074 0.0173
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.04 0.056
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0089 0.1058 0.1418
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0183 0.0212
Echinococcus multilocularis BRK domain 0.0011 0.0063 0.0061
Schistosoma mansoni DNA repair and recombination protein rad54-related 0.0015 0.0117 0.0135
Loa Loa (eye worm) G-protein coupled receptor 0.0011 0.0067 0.0091
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0011 0.0067 0.0076
Brugia malayi ecdysone receptor 0.0033 0.0349 0.0488
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0018
Loa Loa (eye worm) G-protein coupled receptor 0.0011 0.0067 0.0091
Loa Loa (eye worm) melatonin receptor type 1A 0.0011 0.0067 0.0091
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0429 0.0571
Leishmania major hypothetical protein, conserved 0.0009 0.0034 0.0038
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0074 0.0101
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0113 0.1373 0.1613
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0164 0.0258
Echinococcus granulosus steroid dehydrogenase 0.0007 0.0015 0.0015
Schistosoma mansoni steroid dehydrogenase 0.0007 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0018
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Echinococcus granulosus somatostatin receptor 0.0011 0.0067 0.0076
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0012 0.0074 0.0101
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0378 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0139 0.0346
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0071 0.083 0.0828
Loa Loa (eye worm) hypothetical protein 0.0037 0.04 0.056
Echinococcus granulosus GPCR family 2 0.003 0.0311 0.0363
Brugia malayi polk-prov protein 0.003 0.0305 0.0427
Schistosoma mansoni caspase-3 (C14 family) 0.0113 0.1373 0.1613
Echinococcus granulosus para nitrobenzyl esterase 0.0045 0.0492 0.0577
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0071 0.083 0.1166
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.1668 0.1961
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0011 0.0067 0.0064
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0067 0.0064
Mycobacterium ulcerans short-chain dehydrogenase 0.0007 0.0015 0.0025
Brugia malayi hypothetical protein 0.0011 0.0067 0.0091
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0012 0.0074 0.0101
Onchocerca volvulus 0.0007 0.0015 0.003
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0243 0.0539
Echinococcus granulosus neuropeptide receptor 0.0011 0.0067 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0067 0.0076
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0012 0.0074 0.0101
Loa Loa (eye worm) hypothetical protein 0.0264 0.3313 0.4665
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0007 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0018
Echinococcus multilocularis caspase 0.0113 0.1373 0.1371
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Leishmania major quinonoid dihydropteridine reductase 0.0007 0.0015 0.0013
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Loa Loa (eye worm) DR-78 0.0033 0.0349 0.0488
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Schistosoma mansoni Smad4 0.0007 0.0009 0.0008
Brugia malayi nuclear receptor RXR 0.0033 0.0349 0.0488
Loa Loa (eye worm) hypothetical protein 0.0118 0.1442 0.2028
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0012 0.0074 0.0084
Loa Loa (eye worm) hypothetical protein 0.0037 0.04 0.056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0071 0.083 0.1166
Brugia malayi Death domain containing protein 0.0014 0.0098 0.0134
Echinococcus multilocularis nAChR subunit 0.0012 0.0074 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0067 0.0076
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0007 0.0015 0.0292
Loa Loa (eye worm) BRM protein 0.0034 0.0351 0.0491
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0584 0.7428 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0292
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Trypanosoma cruzi DNA repair and recombination protein RAD54, putative 0.0015 0.0117 0.0151
Onchocerca volvulus 0.0007 0.0005 0.0007
Brugia malayi nuclear receptor NHR-88 0.0071 0.083 0.1166
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Schistosoma mansoni steroid dehydrogenase 0.0007 0.0015 0.0015
Brugia malayi bZIP transcription factor family protein 0.0081 0.0963 0.1353
Echinococcus multilocularis ETS transcription factor Elf 2 0.002 0.018 0.0178
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0005 0.0012
Brugia malayi ecdysteroid receptor 0.0071 0.083 0.1166
Onchocerca volvulus 0.0012 0.0074 0.0173
Echinococcus multilocularis conserved hypothetical protein 0.0007 0.0015 0.0013
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0469 0.4121
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.014 0.1719 0.2419
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Brugia malayi mothers against decapentaplegic homolog 3 0.0007 0.0009 0.001
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0007 0.0015 0.0292
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.2859 0.3362
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0067 0.0064
Schistosoma mansoni polypyrimidine tract binding protein 0.0012 0.0073 0.0083
Echinococcus multilocularis retinol dehydrogenase 11 0.0007 0.0015 0.0013
Brugia malayi topoisomerase 0.0019 0.0164 0.0227
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0011 0.0067 0.0076
Echinococcus granulosus dna repair and recombination protein rad54 0.0015 0.0117 0.0135
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0336 0.4241 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0071 0.083 0.1166
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0297 0.3746 0.5274
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0015 0.0117 0.0162
Loa Loa (eye worm) intermediate filament protein 0.0052 0.0589 0.0827
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0007 0.0015 0.0013
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0214 0.6416
Loa Loa (eye worm) hypothetical protein 0.0012 0.0073 0.0099
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.083 0.0828
Trichomonas vaginalis steroid dehydrogenase, putative 0.0007 0.0015 0.0024
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0007 0.0015 0.0024
Schistosoma mansoni retinal dehydrogenase 0.0007 0.0015 0.0015
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0214 0.0538
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.1162 0.1365
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0429 0.0571
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Echinococcus granulosus intermediate filament protein 0.0052 0.0589 0.0691
Echinococcus granulosus apoptotic protease activating factor 1 0.004 0.0431 0.0505
Onchocerca volvulus 0.0052 0.0589 0.1421
Onchocerca volvulus 0.0011 0.0067 0.0156
Schistosoma mansoni nAChR subunit 0.0012 0.0074 0.0084
Onchocerca volvulus 0.0071 0.083 0.2004
Brugia malayi Steroid receptor seven-up type 2 0.0071 0.083 0.1166
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Loa Loa (eye worm) hypothetical protein 0.0017 0.0139 0.0193
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0096 0.1149 0.2704
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.068 0.1744
Echinococcus granulosus carbonyl reductase 1 0.0007 0.0015 0.0015
Echinococcus multilocularis g protein coupled receptor 0.0011 0.0067 0.0064
Schistosoma mansoni BC026374 protein (S09 family) 0.0045 0.0492 0.0577
Loa Loa (eye worm) hypothetical protein 0.0017 0.0139 0.0193
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0071 0.083 0.0974
Loa Loa (eye worm) hypothetical protein 0.0096 0.1158 0.1629
Trypanosoma cruzi metacaspase, putative 0.0043 0.0469 0.0624
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0349 0.0488
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0115 0.0133
Trichomonas vaginalis glucosylceramidase, putative 0.0327 0.4132 0.6517
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0011 0.0067 0.0064
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0007 0.0015 0.0205
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0121 0.0119
Echinococcus multilocularis transient receptor potential cation channel 0.0007 0.0015 0.0013
Onchocerca volvulus 0.0064 0.0739 0.1783
Echinococcus granulosus ETS transcription factor Elf 1 0.002 0.018 0.0209
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0007 0.0015 0.003
Echinococcus granulosus SPRY domain containing protein 0.0015 0.0117 0.0135
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0153 0.0198
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0018
Echinococcus multilocularis smad 0.0016 0.0121 0.0119
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Schistosoma mansoni opsin-like receptor 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.002 0.018 0.025
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0125 0.0161
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0011 0.0067 0.0076
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0153 0.0381
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.002 0.018 0.025
Onchocerca volvulus 0.0007 0.0015 0.003
Onchocerca volvulus 0.0007 0.0005 0.0007
Brugia malayi hypothetical protein 0.0033 0.0349 0.0488
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0164 0.0258
Trypanosoma brucei unspecified product 0.001 0.0043 0.0051
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.033 0.0849
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.5004 0.5003
Echinococcus granulosus mothers against decapentaplegic 2 0.0007 0.0009 0.0008
Entamoeba histolytica hypothetical protein, conserved 0.0007 0.0015 0.003
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0115 0.2371
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0125 0.0161
Echinococcus multilocularis g-protein coupled receptor 0.0011 0.0067 0.0064
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Onchocerca volvulus 0.004 0.0431 0.1038
Brugia malayi G-protein coupled receptor 0.0011 0.0067 0.0091
Loa Loa (eye worm) hypothetical protein 0.0028 0.0277 0.0387
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0011 0.0067 0.0076
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.8498 0.8498
Trypanosoma cruzi metacaspase, putative 0.0043 0.0469 0.0624
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.0074 0.0072
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0127 0.0326
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0033 0.0349 0.0346
Schistosoma mansoni caspase-7 (C14 family) 0.0113 0.1373 0.1613
Schistosoma mansoni hypothetical protein 0.0039 0.0425 0.0498
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0183 0.0397
Trypanosoma cruzi polypyrimidine tract-binding protein, putative 0.0012 0.0073 0.009
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0007 0.0015 0.0036
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0243 0.0339
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0007 0.0015 0.003
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0115 0.0113
Onchocerca volvulus 0.0011 0.0067 0.0156
Loa Loa (eye worm) LGC-31 protein 0.0012 0.0074 0.0101
Echinococcus granulosus GA binding protein alpha chain 0.014 0.1719 0.2021
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0534 0.0625
Schistosoma mansoni gabp alpha 0.014 0.1719 0.2021
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0007 0.0015 0.003
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0012 0.0074 0.0101
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0098 0.0134
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0036
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0127 0.0326
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.003 0.0311 0.0309
Trypanosoma cruzi metacaspase, putative 0.0043 0.0469 0.0624
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0081 0.0963 0.0961
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0469 0.0739
Onchocerca volvulus Huntingtin homolog 0.0118 0.1442 0.3486
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0007 0.0015 0.003
Onchocerca volvulus Cell death protein 3 homolog 0.0083 0.0981 0.237
Brugia malayi isocitrate dehydrogenase 0.0015 0.0115 0.0159
Leishmania major short chain dehydrogenase/reductase, putative 0.0007 0.0015 0.0013
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0121 0.014
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0018
Schistosoma mansoni opsin-like receptor 0.0011 0.0067 0.0076
Brugia malayi latrophilin 2 splice variant baaae 0.0066 0.0766 0.1076
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.068 0.0798
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0444 0.052
Brugia malayi hypothetical protein 0.0011 0.0067 0.0091
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0113 0.1373 0.1371
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0011 0.0067 0.0091
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0164 0.0213
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Schistosoma mansoni hypothetical protein 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0051 0.0577 0.081
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0164 0.0258
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0074 0.0101
Schistosoma mansoni polypyrimidine tract binding protein 0.0012 0.0073 0.0083
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0007 0.0015 0.0036
Schistosoma mansoni inositol monophosphatase 0.0036 0.0378 0.0442
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0378 0.0442
Brugia malayi Carboxylesterase family protein 0.0264 0.3313 0.4665
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0005 0.0012
Echinococcus multilocularis glycine receptor subunit beta 0.0012 0.0074 0.0072
Mycobacterium ulcerans ketoacyl reductase 0.0007 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Loa Loa (eye worm) type III restriction enzyme 0.0015 0.0117 0.0162
Onchocerca volvulus 0.0028 0.0276 0.0662
Onchocerca volvulus 0.0011 0.0067 0.0156
Mycobacterium ulcerans short-chain dehydrogenase 0.0007 0.0015 0.0025
Trypanosoma brucei Metacaspase-4 0.0043 0.0469 0.0624
Echinococcus granulosus DNA repair and recombination protein RAD54B 0.0015 0.0117 0.0135
Echinococcus granulosus ETS domain containing protein Elk 1 0.002 0.018 0.0209
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Plasmodium falciparum DNA repair and recombination protein RAD54, putative 0.0015 0.0117 0.2416
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0429 0.0571
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0214 0.028
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0183 0.3826
Brugia malayi CHE-14 protein 0.0041 0.0444 0.0622
Schistosoma mansoni smad 0.0007 0.0009 0.0008
Brugia malayi intermediate filament protein 0.0052 0.0589 0.0827
Schistosoma mansoni steroid dehydrogenase 0.0007 0.0015 0.0015
Onchocerca volvulus Sepiapterin reductase homolog 0.0007 0.0015 0.003
Echinococcus multilocularis Ankyrin 0.0014 0.0099 0.0097
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0011 0.0067 0.0091
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0018
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0005 0.0004
Echinococcus multilocularis caspase 2 0.0083 0.0981 0.0979
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0164 0.0258
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0232 0.0306
Echinococcus multilocularis BRK domain containing protein 0.0011 0.0063 0.0061
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0007 0.0015 0.0013
Echinococcus multilocularis orexin receptor type 2 0.0011 0.0067 0.0064
Schistosoma mansoni growth hormone secretagogue receptor 0.0011 0.0067 0.0076
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0011 0.0067 0.0076
Schistosoma mansoni smad1 5 8 and 0.0016 0.0121 0.014
Echinococcus granulosus g protein coupled receptor 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0009 0.0034 0.0044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0067 0.0064
Schistosoma mansoni biogenic amine receptor 0.0011 0.0067 0.0076
Brugia malayi follicle stimulating hormone receptor 0.0011 0.0067 0.0091
Brugia malayi DKFZp564C0469 protein 0.0019 0.0164 0.0227
Echinococcus granulosus neuropeptide s receptor 0.0011 0.0067 0.0076
Echinococcus multilocularis BRK domain containing protein 0.0011 0.0063 0.0061
Trichomonas vaginalis glucosylceramidase, putative 0.0499 0.634 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0007 0.0015 0.0036
Loa Loa (eye worm) oxidoreductase 0.0007 0.0015 0.0018
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.0492 0.0577
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0349 0.0408
Mycobacterium ulcerans carveol-like dehydrogenase 0.0007 0.0015 0.0025
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0029 0.0027
Onchocerca volvulus 0.0014 0.0101 0.024
Trypanosoma brucei metacaspase MCA2 0.0043 0.0469 0.0624
Brugia malayi hypothetical protein 0.0019 0.0164 0.0227
Echinococcus granulosus biogenic amine 5HT receptor 0.0011 0.0067 0.0076
Echinococcus multilocularis geminin 0.0327 0.4132 0.4131
Schistosoma mansoni hypothetical protein 0.003 0.0311 0.0363
Onchocerca volvulus 0.0007 0.0015 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.4359 0.6875
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0429 0.0571
Loa Loa (eye worm) hypothetical protein 0.0071 0.083 0.1166
Brugia malayi RNA, U transporter 1 0.0079 0.0938 0.1319
Loa Loa (eye worm) hypothetical protein 0.0048 0.0534 0.0749
Echinococcus granulosus lamin dm0 0.0052 0.0589 0.0691
Brugia malayi Cation transporter family protein 0.0012 0.0074 0.0101
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0164 0.0213
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0429 0.0571
Loa Loa (eye worm) hypothetical protein 0.0066 0.0766 0.1076
Loa Loa (eye worm) hypothetical protein 0.0043 0.0469 0.0657
Onchocerca volvulus 0.0045 0.0492 0.1187
Brugia malayi oxidoreductase 0.0007 0.0015 0.0018
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Trypanosoma brucei short-chain dehydrogenase, putative 0.0007 0.0015 0.0013
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0084
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0183 0.018
Echinococcus multilocularis CAAX prenyl protease 2 0.0089 0.1058 0.1056
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0011 0.0067 0.0064
Schistosoma mansoni biogenic amine receptor 0.0011 0.0067 0.0076
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0153 0.0198
Brugia malayi hypothetical protein 0.0106 0.1277 0.1795
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0045 0.0492 0.049
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0099 0.0136
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0011 0.0067 0.0091
Schistosoma mansoni carbonyl reductase 0.0007 0.0015 0.0015
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0469 0.4121
Toxoplasma gondii carbonyl reductase 1, putative 0.0007 0.0015 0.0084
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0074 0.0084
Brugia malayi Calcitonin receptor-like protein seb-1 0.0096 0.1158 0.1629
Brugia malayi Muscleblind-like protein 0.0289 0.3633 0.5116
Onchocerca volvulus 0.0011 0.0067 0.0156
Echinococcus granulosus biogenic amine 5HT receptor 0.0011 0.0067 0.0076
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0099 0.0136
Entamoeba histolytica DNA repair protein, putative 0.0015 0.0117 0.0271
Trypanosoma brucei CAAX amino terminal protease, putative 0.0089 0.1058 0.1418
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.021 0.0331
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.021 0.0331
Mycobacterium ulcerans oxidoreductase 0.0007 0.0015 0.0025
Plasmodium falciparum protease, putative 0.0018 0.0154 0.3205
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0153 0.3794
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0007 0.0015 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.083 0.1166
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0011 0.0067 0.0076
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0183 0.0254
Onchocerca volvulus 0.0045 0.0492 0.1187
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0243 0.2109
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0099 0.0136
Mycobacterium ulcerans ketoacyl reductase 0.0007 0.0015 0.0025
Onchocerca volvulus 0.0052 0.0589 0.1421
Trypanosoma cruzi hypothetical protein, conserved 0.0007 0.0015 0.0013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.083 0.1166
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0349 0.0408
Trichomonas vaginalis glucosylceramidase, putative 0.0327 0.4132 0.6517
Echinococcus granulosus neuropeptide Y receptor 0.0011 0.0067 0.0076
Trypanosoma cruzi DNA polymerase eta, putative 0.0014 0.0099 0.0126
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0183 0.1576
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0012 0.0074 0.0084
Echinococcus granulosus FTZ F1 alpha 0.0071 0.083 0.0974
Echinococcus multilocularis sex peptide receptor 0.0011 0.0067 0.0064
Echinococcus granulosus ETS transcription factor Elf 2 0.002 0.018 0.0209
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0025
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0071 0.083 0.0974
Echinococcus granulosus oxidoreductase 0.0007 0.0015 0.0015
Entamoeba histolytica hypothetical protein 0.0106 0.1277 0.3006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0.0067 0.0076
Brugia malayi hypothetical protein 0.0011 0.0067 0.0091
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0276 0.3473 0.4671
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0232 0.2017
Brugia malayi hypothetical protein 0.0007 0.0015 0.0018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0469 0.0739
Echinococcus granulosus peptide allatostatin:somatostatin 0.0011 0.0067 0.0076
Echinococcus multilocularis neuropeptide Y receptor 0.0011 0.0067 0.0064
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0232 0.0306
Onchocerca volvulus 0.0007 0.0015 0.003
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0045 0.0492 0.1269
Entamoeba histolytica hypothetical protein 0.0023 0.021 0.0489
Loa Loa (eye worm) hypothetical protein 0.0017 0.0139 0.0193
Trypanosoma brucei Double RNA binding domain protein 3 0.0009 0.0034 0.0038
Leishmania major oxidoreductase-like protein 0.0007 0.0015 0.0013
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0045 0.0492 0.0777
Toxoplasma gondii exonuclease III APE 0.0018 0.0153 0.1309
Echinococcus multilocularis neuropeptides capa receptor 0.0011 0.0067 0.0064
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0025
Mycobacterium ulcerans oxidoreductase 0.0007 0.0015 0.0025
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0164 0.0161
Loa Loa (eye worm) latrophilin receptor protein 2 0.003 0.0311 0.0435
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0071 0.083 0.1166
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0071 0.083 0.1166
Echinococcus multilocularis Chromo domain 0.0011 0.0064 0.0061
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0089 0.1058 0.1243
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0011 0.0067 0.0076
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0012 0.0074 0.0101
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Leishmania major short chain dehydrogenase-like protein 0.0007 0.0015 0.0013
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0074 0.0101
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0264 0.3313 0.3897
Echinococcus multilocularis glycine receptor subunit beta 0.0012 0.0074 0.0072
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0012 0.0074 0.0101
Loa Loa (eye worm) hypothetical protein 0.0019 0.0164 0.0227
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0033 0.0349 0.0408
Brugia malayi hypothetical protein 0.0045 0.0492 0.069
Toxoplasma gondii hypothetical protein 0.0018 0.0154 0.1321
Echinococcus granulosus geminin 0.0327 0.4132 0.4861
Loa Loa (eye worm) hypothetical protein 0.004 0.0431 0.0604
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Echinococcus granulosus protein C ets 2 0.002 0.018 0.0209
Brugia malayi F/Y-rich N-terminus family protein 0.0008 0.0028 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0018
Schistosoma mansoni steroid dehydrogenase 0.0007 0.0015 0.0015
Onchocerca volvulus 0.0023 0.0214 0.0512
Leishmania major quinonoid dihydropteridine reductase 0.0007 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.003 0.0311 0.0435
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Onchocerca volvulus 0.0007 0.0015 0.003
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0181 0.0236
Trichomonas vaginalis glucosylceramidase, putative 0.0327 0.4132 0.6517
Echinococcus multilocularis chromodomain helicase DNA binding protein 7 0.0011 0.0063 0.0061
Echinococcus multilocularis carbonyl reductase 1 0.0007 0.0015 0.0013
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0429 0.0571
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0007 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Echinococcus multilocularis nuclear receptor nhr 48 0.0033 0.0349 0.0346
Schistosoma mansoni smad1 5 8 and 0.0016 0.0121 0.014
Schistosoma mansoni intermediate filament proteins 0.0052 0.0589 0.0691
Schistosoma mansoni hypothetical protein 0.0106 0.1277 0.15
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.0469 0.0624
Echinococcus granulosus hypothetical protein 0.0007 0.0015 0.0015
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0074 0.0084
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0153 0.0326
Echinococcus multilocularis ets variant gene 4 0.002 0.018 0.0178
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0007 0.0015 0.0013
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0084
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.083 0.1166
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0153 0.3178
Echinococcus multilocularis g protein coupled receptor 0.0011 0.0067 0.0064
Echinococcus granulosus lamin 0.0052 0.0589 0.0691
Echinococcus multilocularis dna repair and recombination protein rad54 0.0015 0.0117 0.0115
Loa Loa (eye worm) nuclear hormone receptor 0.0033 0.0349 0.0488
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0071 0.083 0.1166
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0181 0.0465
Schistosoma mansoni DNA repair and recombination protein rad54-related 0.0015 0.0117 0.0135
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0019 0.0164 0.0381
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0164 0.0213
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0007 0.0015 0.0013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0082 0.0975 0.1306
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0005 0.0012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0074 0.0101
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0007 0.0015 0.0025
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0005 0.0009
Schistosoma mansoni cpg binding protein 0.0029 0.0296 0.0346
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0071 0.083 0.1166
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0214 0.0298
Plasmodium falciparum flap endonuclease 1 0.0025 0.0243 0.5119
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0429 0.0677
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0033 0.0349 0.0488
Schistosoma mansoni hypothetical protein 0.0395 0.5004 0.5887
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0349 0.0346
Brugia malayi Tachykinin-like peptides receptor 99D 0.0011 0.0067 0.0091
Loa Loa (eye worm) MH2 domain-containing protein 0.0007 0.0009 0.001
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0043 0.0469 0.0657
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.068 0.1744
Echinococcus granulosus WW domain containing oxidoreductase 0.0007 0.0015 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0018 0.0154 0.0395
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0558 0.71 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0019 0.0164 0.0227
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0378 0.0502
Echinococcus granulosus dro:myosuppressin receptor 0.0011 0.0067 0.0076
Echinococcus granulosus acetylcholinesterase 0.0264 0.3313 0.3897
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Entamoeba histolytica hypothetical protein 0.0019 0.0164 0.0381
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0469 0.0739
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0007 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0007 0.0009 0.001
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0277 0.2418
Mycobacterium tuberculosis Conserved hypothetical protein 0.0018 0.0154 0.0395
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0012 0.0074 0.0101
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0098 0.0231
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0214 0.0498
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0153 0.0241
Echinococcus multilocularis caspase 8 0.0043 0.0469 0.0467
Echinococcus multilocularis muscleblind protein 0.0289 0.3633 0.3632
Loa Loa (eye worm) hypothetical protein 0.0045 0.0492 0.069
Echinococcus multilocularis cpg binding protein 0.0029 0.0296 0.0294
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0008 0.0006
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0115 0.0113
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0349 0.0488
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0007 0.0015 0.0013
Mycobacterium ulcerans integral membrane protein 0.0018 0.0154 0.0384
Loa Loa (eye worm) carboxylesterase 0.0264 0.3313 0.4665
Loa Loa (eye worm) hypothetical protein 0.0019 0.0164 0.0227
Loa Loa (eye worm) hypothetical protein 0.0014 0.0098 0.0134
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0007 0.0015 0.0024
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0033 0.0349 0.0408
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.003 0.0311 0.0363
Echinococcus multilocularis BC026374 protein (S09 family) 0.0045 0.0492 0.049
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Schistosoma mansoni carbonyl reductase 0.0007 0.0015 0.0015
Schistosoma mansoni nuclear receptor 0.0033 0.0349 0.0408
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0349 0.0346
Schistosoma mansoni netrin receptor unc5 0.0014 0.0098 0.0112
Echinococcus granulosus neuropeptides capa receptor 0.0011 0.0067 0.0076
Schistosoma mansoni ets-related 0.0425 0.5385 0.6336
Loa Loa (eye worm) oxidoreductase 0.0007 0.0015 0.0018
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0292
Trypanosoma brucei DNA repair and recombination protein RAD54, putative 0.0015 0.0117 0.0151
Onchocerca volvulus 0.0007 0.0015 0.003
Loa Loa (eye worm) fli-1 protein 0.0425 0.5385 0.7585
Schistosoma mansoni ets-related 0.002 0.018 0.0209
Onchocerca volvulus 0.0012 0.0074 0.0173
Schistosoma mansoni DNA ligase IV 0.0019 0.0164 0.019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Onchocerca volvulus 0.0007 0.0005 0.0007
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0429 0.1096
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0025
Echinococcus granulosus expressed conserved protein 0.0089 0.1069 0.1255
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0232 0.4895
Mycobacterium tuberculosis Probable integral membrane protein 0.0018 0.0154 0.0395
Echinococcus granulosus serotonin receptor 0.0011 0.0067 0.0076
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0153 0.0212
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0115 0.0148
Brugia malayi Carboxylesterase family protein 0.0045 0.0492 0.069
Loa Loa (eye worm) hypothetical protein 0.0007 0.0005 0.0004
Leishmania major RNA-binding protein, putative 0.0009 0.0034 0.0038
Schistosoma mansoni steroid dehydrogenase 0.0007 0.0015 0.0015
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0378 0.0376
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0011 0.0067 0.0076
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0073 0.0099
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0349 0.0408
Entamoeba histolytica Ran family GTPase 0.0021 0.0183 0.0425
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0005 0.0004
Leishmania major quinonoid dihydropteridine reductase 0.0007 0.0015 0.0013
Onchocerca volvulus 0.0007 0.0015 0.003
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0011 0.0067 0.0076
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0139 0.0193
Loa Loa (eye worm) hypothetical protein 0.0052 0.0589 0.0827
Onchocerca volvulus 0.0011 0.0067 0.0156
Mycobacterium ulcerans hypothetical protein 0.0023 0.0214 0.0538
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0834 0.0979
Schistosoma mansoni steroid dehydrogenase 0.0007 0.0015 0.0015
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0153 0.0177
Schistosoma mansoni hypothetical protein 0.0039 0.0425 0.0498
Echinococcus granulosus neuropeptides capa receptor 0.0011 0.0067 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0125 0.0161
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0378 0.3313
Loa Loa (eye worm) neuropeptide F receptor 0.0011 0.0067 0.0091
Echinococcus granulosus glycine receptor subunit beta 0.0012 0.0074 0.0084
Onchocerca volvulus Bile acid receptor homolog 0.0071 0.083 0.2004
Schistosoma mansoni histamine h1 receptor 0.0011 0.0067 0.0076
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0012 0.0074 0.0072
Brugia malayi hypothetical protein 0.0016 0.0121 0.0167
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0071 0.083 0.2004
Echinococcus multilocularis dna polymerase kappa 0.004 0.0429 0.0427
Schistosoma mansoni alpha-1 adrenergic receptor 0.0011 0.0067 0.0076
Mycobacterium tuberculosis Possible oxidoreductase 0.0007 0.0015 0.0036
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0214 0.0538
Onchocerca volvulus 0.0045 0.0492 0.1187
Echinococcus granulosus G protein coupled receptor 139 0.0011 0.0067 0.0076
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0007 0.0015 0.0084
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.0074 0.0084
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0005 0.0004
Echinococcus granulosus CAAX prenyl protease 2 0.0089 0.1058 0.1243
Echinococcus multilocularis protein patched 0.0041 0.0444 0.0442
Onchocerca volvulus 0.0011 0.0067 0.0156
Schistosoma mansoni steroid hormone receptor ad4bp 0.0071 0.083 0.0974
Echinococcus multilocularis carboxylesterase 5A 0.0264 0.3313 0.3312
Toxoplasma gondii oxidoreductase, putative 0.0007 0.0015 0.0084
Brugia malayi nuclear hormone receptor family member nhr-6 0.0033 0.0349 0.0488
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0033 0.0349 0.0408
Schistosoma mansoni survival motor neuron protein 0.0047 0.0519 0.0608
Brugia malayi dehydrogenases, short chain protein 2 0.0007 0.0015 0.0018
Echinococcus multilocularis global transcription activator snf2l2 0.0065 0.0754 0.0752
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0067 0.0064
Mycobacterium tuberculosis Probable oxidoreductase 0.0007 0.0015 0.0036
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.01 0.1206 0.1617
Trichomonas vaginalis glucosylceramidase, putative 0.0327 0.4132 0.6517
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0089 0.1058 0.1418
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0214 0.6416
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0019 0.0164 0.4096
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0067 0.0064
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0089 0.1058 0.1243
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0011 0.0067 0.0064
Brugia malayi MH1 domain containing protein 0.0016 0.0121 0.0167
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0012 0.0074 0.0084
Schistosoma mansoni hypothetical protein 0.0327 0.4132 0.4861
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0469 0.0739
Brugia malayi G protein-coupled receptor F59B2.13 0.0011 0.0067 0.0091
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0067 0.0064
Echinococcus multilocularis protein dispatched 1 0.0047 0.0518 0.0516
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0025
Loa Loa (eye worm) steroid hormone receptor 0.0071 0.083 0.1166
Leishmania major quinonoid dihydropteridine reductase 0.0007 0.0015 0.0013
Echinococcus multilocularis ETS domain containing protein Elk 1 0.002 0.018 0.0178
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0007 0.0015 0.0036
Echinococcus multilocularis steroid dehydrogenase 0.0007 0.0015 0.0013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.083 0.0974
Brugia malayi Carboxylesterase family protein 0.0045 0.0492 0.069
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.0492 0.0577
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0067 0.0076
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0019 0.0164 0.4876
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0115 0.0148
Loa Loa (eye worm) oxidoreductase 0.0007 0.0005 0.0004
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0121 0.014
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0012 0.0074 0.0084
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0007 0.0015 0.0024
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0115 0.0113
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0214 0.0549
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0007 0.0015 0.0024
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0499 0.634 0.893
Loa Loa (eye worm) hypothetical protein 0.0025 0.0242 0.0338
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0121 0.0167
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0037 0.04 0.0468
Onchocerca volvulus 0.0007 0.0015 0.003
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0007 0.0015 0.0013
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0007 0.0009 0.0017
Brugia malayi conserved hypotetical protein 0.0033 0.0349 0.0488
Trypanosoma cruzi hypothetical protein, conserved 0.0007 0.0015 0.0013
Schistosoma mansoni neuroligin 3 (S09 family) 0.0045 0.0492 0.0577
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0166 0.2055 0.2417
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.003 0.0311 0.0309
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0067 0.0076
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0089 0.1058 0.1418
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0071 0.083 0.1166
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0005 0.0012
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0007 0.0015 0.0036
Echinococcus multilocularis thyroid hormone receptor alpha 0.0071 0.083 0.0828
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0074 0.0101
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.0074 0.0084
Loa Loa (eye worm) oxidoreductase 0.0007 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0023 0.0214 0.0298
Leishmania major importin beta-1 subunit, putative 0.0023 0.021 0.0275
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0106 0.1277 0.15
Schistosoma mansoni Smad4 0.0007 0.0009 0.0008
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0007 0.0015 0.003
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0071 0.083 0.0828
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0183 0.0254
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0153 0.015
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0129 0.1574 0.1572
Loa Loa (eye worm) oxidoreductase 0.0007 0.0015 0.0018
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0045 0.0492 0.1269
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0378 0.0596
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Schistosoma mansoni nAChR subunit 0.0012 0.0074 0.0084
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0214 0.0298
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Loa Loa (eye worm) neuropeptide F receptor 0.0011 0.0067 0.0091
Echinococcus multilocularis dna repair and recombination protein rad54 0.0015 0.0117 0.0115
Brugia malayi Ets-domain containing protein 0.014 0.1719 0.2419
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0007 0.0015 0.0205
Echinococcus granulosus 7TM GPCR rhodopsin 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0041 0.0444 0.0622
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Schistosoma mansoni ap endonuclease 0.0018 0.0153 0.0177
Echinococcus granulosus retinol dehydrogenase 11 0.0007 0.0015 0.0015
Schistosoma mansoni inositol monophosphatase 0.0036 0.0378 0.0442
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0007 0.0015 0.0024
Leishmania major GTP-binding protein, putative 0.0021 0.0183 0.0239
Schistosoma mansoni importin beta-1 0.0028 0.0277 0.0324
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Echinococcus granulosus microtubule associated protein 2 0.0667 0.8498 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0007 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Echinococcus granulosus SPRY domain containing protein 0.0015 0.0117 0.0135
Loa Loa (eye worm) hypothetical protein 0.0071 0.083 0.1166
Onchocerca volvulus 0.0012 0.0074 0.0173
Plasmodium vivax importin-beta 2, putative 0.0028 0.0277 0.5868
Loa Loa (eye worm) hypothetical protein 0.0095 0.1143 0.1607
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0164 0.0258
Brugia malayi MH1 domain containing protein 0.0009 0.0031 0.004
Loa Loa (eye worm) hypothetical protein 0.0037 0.04 0.056
Echinococcus multilocularis carbonyl reductase 1 0.0007 0.0015 0.0013
Trichomonas vaginalis spcc417.12 protein, putative 0.0045 0.0492 0.0777
Entamoeba histolytica hypothetical protein, conserved 0.0007 0.0015 0.003
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0012 0.0074 0.0072
Brugia malayi MH2 domain containing protein 0.0231 0.2887 0.4065
Brugia malayi CXXC zinc finger family protein 0.0028 0.0276 0.0385
Brugia malayi RE15519p 0.0011 0.0067 0.0091
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0007 0.0015 0.0013
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0007 0.0015 0.0036
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0469 0.0739
Plasmodium vivax protease, putative 0.0018 0.0154 0.3205
Leishmania major hypothetical protein, conserved 0.0007 0.0015 0.0013
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0025 0.0242 0.024
Schistosoma mansoni smad1 5 8 and 0.0016 0.0121 0.014
Loa Loa (eye worm) hypothetical protein 0.0045 0.0492 0.069
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.04 0.056
Mycobacterium tuberculosis Probable oxidoreductase 0.0007 0.0015 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0011 0.0067 0.0076
Echinococcus multilocularis caspase 3 0.007 0.0823 0.0821
Loa Loa (eye worm) hypothetical protein 0.0017 0.0139 0.0193
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0025 0.0242 0.0283
Echinococcus multilocularis oxidoreductase 0.0007 0.0015 0.0013
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0019 0.0164 0.0227
Brugia malayi Uncoordinated protein 44 0.0014 0.0098 0.0134
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0214 0.0298
Loa Loa (eye worm) hypothetical protein 0.0071 0.083 0.1166
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0277 0.0366
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0067 0.0076
Loa Loa (eye worm) MH2 domain-containing protein 0.0231 0.2887 0.4065
Plasmodium vivax metacaspase 1, putative 0.0043 0.0469 1
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Loa Loa (eye worm) carboxylesterase 0.0045 0.0492 0.069
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0121 0.0167
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.0469 0.0624
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0012 0.0074 0.0072
Plasmodium falciparum polypyrimidine tract-binding protein, putative 0.0012 0.0073 0.1449
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.1143 0.1342
Trypanosoma brucei unspecified product 0.001 0.0043 0.0051
Brugia malayi hypothetical protein 0.0024 0.0232 0.0324
Entamoeba histolytica short chain dehydrogenase family protein 0.0007 0.0015 0.003
Schistosoma mansoni adenoreceptor 0.0011 0.0067 0.0076
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.003 0.0311 0.0435
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Onchocerca volvulus Glucosylceramidase homolog 0.0327 0.4132 1
Echinococcus granulosus caspase 3 0.007 0.0823 0.0966
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0127 0.0326
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0011 0.0067 0.0064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0067 0.0076
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0232 0.0306
Echinococcus multilocularis lamin dm0 0.0052 0.0589 0.0587
Mycobacterium tuberculosis Probable oxidoreductase 0.0007 0.0015 0.0036
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0005 0.0004
Onchocerca volvulus 0.0019 0.0164 0.0391
Echinococcus granulosus hypothetical protein 0.0011 0.0067 0.0076
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0015 0.0117 0.0162
Echinococcus granulosus global transcription activator snf2l2 0.0065 0.0754 0.0885
Echinococcus multilocularis dna polymerase eta 0.0014 0.0099 0.0096
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0007 0.0015 0.0013
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0007 0.0015 0.0015
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0007 0.0015 0.0084
Onchocerca volvulus 0.0011 0.0067 0.0156
Schistosoma mansoni hypothetical protein 0.0014 0.0098 0.0112
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Echinococcus granulosus ETS transcription factor Elf 2 0.002 0.018 0.0209
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0617 0.5441
Brugia malayi hypothetical protein 0.0037 0.04 0.056
Echinococcus multilocularis ewsr:fli fusion protein type 0.002 0.018 0.0178
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0139 0.2885
Loa Loa (eye worm) hypothetical protein 0.0045 0.0492 0.069
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0469 0.0739
Brugia malayi hypothetical protein 0.0011 0.0067 0.0091
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0153 0.0241
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0071 0.083 0.1166
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0007 0.0015 0.0013
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0029 0.0032
Loa Loa (eye worm) D-ets-2 protein 0.002 0.018 0.025
Echinococcus multilocularis tumor protein p63 0.0326 0.412 0.4118
Brugia malayi hypothetical protein 0.0037 0.04 0.056
Brugia malayi hypothetical protein 0.0007 0.0015 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0071 0.083 0.1166
Schistosoma mansoni neuropeptide receptor 0.0011 0.0067 0.0076
Brugia malayi Inositol-1 0.0036 0.0378 0.0529
Plasmodium vivax polypyrimidine tract binding protein, putative 0.0012 0.0073 0.1449
Entamoeba histolytica hypothetical protein 0.0106 0.1277 0.3006
Schistosoma mansoni biogenic amine (5HT) receptor 0.0011 0.0067 0.0076
Brugia malayi Pax transcription activation domain interacting protein 0.0019 0.0164 0.0227
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0115 0.0113
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.003 0.0311 0.0363
Brugia malayi nuclear hormone receptor family member odr-7 0.0033 0.0349 0.0488
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0098 0.0095
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0007 0.0015 0.0018
Loa Loa (eye worm) oxidoreductase 0.0007 0.0015 0.0018
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0011 0.0067 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0071 0.083 0.1166
Brugia malayi Fli-1 protein 0.0425 0.5385 0.7585
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0082 0.0975 0.1306
Schistosoma mansoni polypyrimidine tract binding protein 0.0009 0.0034 0.0037
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0033 0.0349 0.0488
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0153 0.0355
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Brugia malayi hypothetical protein 0.0011 0.0067 0.0091
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0007 0.0015 0.0013
Plasmodium falciparum metacaspase-like protein 0.0043 0.0469 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0011 0.0067 0.0091
Echinococcus granulosus neuropeptide receptor A26 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Brugia malayi DNA-binding protein D-ETS-3 0.002 0.018 0.025
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0007 0.0015 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0444 0.0701
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0011 0.0067 0.0076
Leishmania major metacaspase, putative 0.0043 0.0469 0.0624
Trichomonas vaginalis importin beta-1, putative 0.0023 0.021 0.0331
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0052 0.0589 0.0827
Echinococcus granulosus cpg binding protein 0.0029 0.0296 0.0346
Loa Loa (eye worm) acetylcholinesterase 1 0.0264 0.3313 0.4665
Plasmodium vivax DNA repair protein RAD54, putative 0.0015 0.0117 0.2416
Mycobacterium ulcerans hypothetical protein 0.0307 0.3874 1
Echinococcus multilocularis lamin 0.0052 0.0589 0.0587
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0007 0.0015 0.0013
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0012 0.0074 0.0084
Echinococcus granulosus neuropeptide FF receptor 2 0.0011 0.0067 0.0076
Brugia malayi Smad1 0.0016 0.0121 0.0167
Echinococcus multilocularis GA binding protein alpha chain 0.014 0.1719 0.1717
Onchocerca volvulus 0.0007 0.0015 0.003
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0584 0.082
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0099 0.0114
Echinococcus multilocularis para nitrobenzyl esterase 0.0045 0.0492 0.049
Brugia malayi hypothetical protein 0.0118 0.1442 0.2028
Schistosoma mansoni helicase 0.0065 0.0754 0.0885
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Leishmania major DNA polymerase kappa, putative 0.002 0.0181 0.0236
Echinococcus multilocularis ecdysone induced protein 78C 0.0071 0.083 0.0828
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0127 0.0326
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0037 0.04 0.056
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Brugia malayi transcription factor E74 isoform 0.002 0.018 0.025
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0012 0.0074 0.0101
Onchocerca volvulus Putative nachr subunit 0.0012 0.0074 0.0173
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0011 0.0067 0.0091
Echinococcus multilocularis BRK domain containing protein 0.0011 0.0063 0.0061
Echinococcus multilocularis jun protein 0.0081 0.0963 0.0961
Echinococcus multilocularis carbonyl reductase 1 0.0007 0.0015 0.0013
Echinococcus multilocularis fmrfamide receptor 0.0011 0.0067 0.0064
Schistosoma mansoni retinoic acid receptor RXR 0.0166 0.2055 0.2417
Schistosoma mansoni topbp1 0.0019 0.0164 0.019
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0429 0.0571
Echinococcus multilocularis steroid dehydrogenase 0.0007 0.0015 0.0013
Schistosoma mansoni hypothetical protein 0.0011 0.0067 0.0076
Echinococcus multilocularis allatostatin A receptor 0.0011 0.0067 0.0064
Schistosoma mansoni hypothetical protein 0.003 0.0311 0.0363
Trypanosoma cruzi hypothetical protein, conserved 0.0007 0.0015 0.0013
Trypanosoma brucei metacaspase 0.0043 0.0469 0.0624
Brugia malayi Carboxylesterase family protein 0.0045 0.0492 0.069
Echinococcus multilocularis expressed conserved protein 0.0089 0.1069 0.1066
Giardia lamblia DINP protein human, muc B family 0.002 0.0181 0.0393
Schistosoma mansoni ets 0.002 0.018 0.0209
Trichomonas vaginalis glucosylceramidase, putative 0.0499 0.634 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0067 0.0076
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0349 0.0408
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0007 0.0015 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0429 0.0571
Schistosoma mansoni hypothetical protein 0.0047 0.0519 0.0608
Mycobacterium leprae Probable oxidoreductase 0.0007 0.0015 0.0292
Loa Loa (eye worm) hypothetical protein 0.0007 0.0005 0.0004
Onchocerca volvulus 0.0012 0.0074 0.0173
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Brugia malayi Dehydrogenases, short chain protein 30 0.0007 0.0015 0.0018
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0007 0.0015 0.003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0011 0.0067 0.0091
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.002 0.018 0.0209
Onchocerca volvulus 0.0011 0.0067 0.0156
Schistosoma mansoni elf1 0.002 0.018 0.0209
Schistosoma mansoni neuropeptide f receptor 76f 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.005 0.0562 0.0789
Loa Loa (eye worm) oxidoreductase 0.0007 0.0015 0.0018
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.0492 0.0577
Echinococcus granulosus carbonyl reductase 1 0.0007 0.0015 0.0015
Echinococcus multilocularis G protein coupled receptor 139 0.0011 0.0067 0.0064
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0007 0.0015 0.0013
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0007 0.0015 0.0013
Echinococcus granulosus muscleblind protein 0.0289 0.3633 0.4274
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0071 0.083 0.1166
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0007 0.0015 0.0018
Schistosoma mansoni short chain dehydrogenase 0.0007 0.0015 0.0015
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0012 0.0074 0.0101
Loa Loa (eye worm) hypothetical protein 0.0024 0.0232 0.0324
Leishmania major pteridine reductase 1 0.0007 0.0015 0.0013
Echinococcus granulosus ETS transcription factor Elf 5 0.002 0.018 0.0209
Loa Loa (eye worm) MH1 domain-containing protein 0.0007 0.0009 0.001
Echinococcus granulosus death domain containing protein 0.0014 0.0098 0.0112
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0278 0.0388
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0071 0.083 0.0974
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0243 0.0383
Trypanosoma cruzi short chain dehydrogenase, putative 0.0007 0.0015 0.0013
Echinococcus multilocularis neuropeptide FF receptor 2 0.0011 0.0067 0.0064
Loa Loa (eye worm) hypothetical protein 0.0071 0.083 0.1166
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0214 0.0538
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0429 0.0677
Entamoeba histolytica DNA repair protein, putative 0.0015 0.0117 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0164 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0164 0.0258
Echinococcus granulosus caspase 8 0.0043 0.0469 0.0549
Echinococcus granulosus thyroid hormone receptor alpha 0.0033 0.0349 0.0408
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.1143 0.1607
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Schistosoma mansoni amine GPCR 0.0011 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0012 0.0074 0.0072
Brugia malayi neuropeptide F receptor 0.0011 0.0067 0.0091
Brugia malayi hypothetical protein 0.0011 0.0067 0.0091
Brugia malayi nuclear hormone receptor 0.0033 0.0349 0.0488
Loa Loa (eye worm) transcription factor SMAD2 0.0231 0.2887 0.4065
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0429 0.0571
Trypanosoma brucei oxidoreductase-like protein 0.0007 0.0015 0.0013
Trypanosoma cruzi FHA domain containing protein, putative 0.0019 0.0164 0.0213
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0089 0.1058 0.1669
Onchocerca volvulus 0.0011 0.0067 0.0156
Giardia lamblia DNA repair protein RAD52 0.0336 0.4241 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Schistosoma mansoni RAR-like nuclear receptor 0.0071 0.083 0.0974
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Trichomonas vaginalis glucosylceramidase, putative 0.0327 0.4132 0.6517
Echinococcus granulosus 7tm_1 domain containing protein 0.0011 0.0067 0.0076
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0.0067 0.0076
Brugia malayi hypothetical protein 0.0019 0.0164 0.0227
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0243 0.0567
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0153 0.0212
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0045 0.0492 0.0577
Schistosoma mansoni caspase-7 (C14 family) 0.0083 0.0981 0.1152
Toxoplasma gondii hypothetical protein 0.0018 0.0154 0.1321
Echinococcus multilocularis neuroligin 0.0045 0.0492 0.049
Plasmodium falciparum metacaspase 1 0.0043 0.0469 1
Schistosoma mansoni smad 0.0016 0.0121 0.014
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Brugia malayi Serotonin receptor 0.0011 0.0067 0.0091
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0676 0.0793
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0214 0.0498
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0018
Brugia malayi nuclear receptor RXR 0.0037 0.04 0.056
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.8498 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.083 0.1166
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0232 0.4895
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.068 0.0909
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0067 0.0064
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.002 0.018 0.025
Echinococcus granulosus BC026374 protein S09 family 0.0045 0.0492 0.0577
Echinococcus granulosus ewsr:fli fusion protein type 0.002 0.018 0.0209
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0106 0.1277 0.1275
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.1143 0.2691
Mycobacterium ulcerans ketoacyl reductase 0.0007 0.0015 0.0025
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0043 0.0469 0.0549
Schistosoma mansoni DNA polymerase eta 0.0014 0.0099 0.0114
Brugia malayi Cation transporter family protein 0.0012 0.0074 0.0101
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0012 0.0074 0.0101
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0008 0.0006
Loa Loa (eye worm) inositol-1 0.0036 0.0378 0.0529
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0018
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0012 0.0074 0.0084
Echinococcus granulosus caspase 0.0113 0.1373 0.1613
Brugia malayi nuclear hormone receptor 0.0071 0.083 0.1166
Trichomonas vaginalis lymphoid specific helicase, putative 0.0012 0.0071 0.0112
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0115 0.0133
Trichomonas vaginalis glucosylceramidase, putative 0.0499 0.634 1
Brugia malayi hypothetical protein 0.0033 0.0349 0.0488
Echinococcus multilocularis 0.0015 0.0117 0.0115
Loa Loa (eye worm) hypothetical protein 0.0228 0.2859 0.4024
Brugia malayi photoreceptor-specific nuclear receptor 0.0071 0.083 0.1166
Entamoeba histolytica CAAX amino terminal protease family 0.0018 0.0154 0.0358
Echinococcus granulosus alpha 1A adrenergic receptor 0.0011 0.0067 0.0076
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0007 0.0015 0.0013
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0007 0.0015 0.0024
Loa Loa (eye worm) hypothetical protein 0.0033 0.0349 0.0488
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.083 0.1166
Loa Loa (eye worm) hypothetical protein 0.0289 0.3633 0.5116
Echinococcus granulosus ecdysone induced protein 78C 0.0071 0.083 0.0974
Loa Loa (eye worm) hypothetical protein 0.0009 0.0034 0.0044
Brugia malayi hypothetical protein 0.0228 0.2859 0.4024
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0584 0.7428 1
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0115 0.0977
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0071 0.083 0.0974
Leishmania major short chain dehydrogenase, putative 0.0007 0.0015 0.0013
Treponema pallidum hypothetical protein 0.0018 0.0154 0.1145
Trichomonas vaginalis glucosylceramidase, putative 0.0499 0.634 1
Schistosoma mansoni neuropeptide receptor 0.0011 0.0067 0.0076
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0071 0.083 0.0974
Schistosoma mansoni gliotactin 0.0045 0.0492 0.0577
Loa Loa (eye worm) hypothetical protein 0.0011 0.0067 0.0091
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0101
Schistosoma mansoni steroid dehydrogenase 0.0007 0.0015 0.0015
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.001 0.0049 0.0388
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0071 0.083 0.1166
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0349 0.0838
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0349 0.0346
Brugia malayi steroid hormone receptor 0.0071 0.083 0.1166
Echinococcus multilocularis neuropeptide Y receptor 0.0011 0.0067 0.0064
Echinococcus multilocularis retinol dehydrogenase 11 0.0007 0.0015 0.0013
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0183 0.0239
Brugia malayi dehydrogenases, short chain protein 9 0.0007 0.0015 0.0018
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0037 0.04 0.0398
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0071 0.083 0.0828
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0007 0.0005 0.0007
Mycobacterium ulcerans short chain dehydrogenase 0.0007 0.0015 0.0025
Entamoeba histolytica deoxycytidyl transferase, putative 0.0014 0.0099 0.0228
Echinococcus granulosus carbonyl reductase 1 0.0007 0.0015 0.0015
Echinococcus granulosus acetylcholinesterase 0.0264 0.3313 0.3897
Loa Loa (eye worm) hypothetical protein 0.0019 0.0164 0.0227
Brugia malayi CAAX amino terminal protease family protein 0.0089 0.1058 0.1487

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 183 nM Inhibition of [3H]-PSB-11 binding to human Adenosine A3 receptor ChEMBL. 11906291
Ki (binding) = 183 nM Inhibition of [3H]-PSB-11 binding to human Adenosine A3 receptor ChEMBL. 11906291
Ki (binding) = 210 nM Inhibition of [3H]-CCPA binding to rat adenosine A1 receptor ChEMBL. 11906291
Ki (binding) = 210 nM Inhibition of [3H]-CCPA binding to rat adenosine A1 receptor ChEMBL. 11906291
Ki (binding) = 250 nM Inhibition of [3H]-ZM-241,385 binding to human adenosine A2B receptor ChEMBL. 11906291
Ki (binding) = 250 nM Inhibition of [3H]-ZM-241,385 binding to human adenosine A2B receptor ChEMBL. 11906291
Ki (binding) = 1400 nM Inhibition of [3H]-MSX-2 binding to rat adenosine A2A receptor ChEMBL. 11906291
Ki (binding) = 1400 nM Inhibition of [3H]-MSX-2 binding to rat adenosine A2A receptor ChEMBL. 11906291
Ratio (binding) = 6 Selectivity ratio of the compound( A2A/A2B) ChEMBL. 11906291
Ratio (binding) = 1 Selectivity ratio of the compound (A1/A2B) ChEMBL. 11906291
Ratio (binding) = 1 Selectivity ratio (A3/A2B). ChEMBL. 11906291
Ratio (binding) = 6 Selectivity ratio of the compound( A2A/A2B) ChEMBL. 11906291

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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