Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.1084 | 0.1084 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0054 | 0.0054 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0207 | 0.2992 | 0.2992 |
Trichomonas vaginalis | importin beta-1, putative | 0.005 | 0.0531 | 0.0634 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.0066 | 0.0016 |
Leishmania major | hypothetical protein, conserved | 0.0055 | 0.062 | 0.0753 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0181 | 0.0181 |
Brugia malayi | Pre-SET motif family protein | 0.0239 | 0.3497 | 0.4431 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0561 | 0.0561 |
Echinococcus multilocularis | dna polymerase eta | 0.002 | 0.0066 | 0.0066 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.0066 | 0.0016 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.0316 | 0.1372 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Brugia malayi | MH1 domain containing protein | 0.002 | 0.0059 | 0.0075 |
Loa Loa (eye worm) | nuclear factor I | 0.002 | 0.0059 | 0.0059 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0061 | 0.0712 | 0.0876 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0531 | 0.0531 |
Schistosoma mansoni | glycogen phosphorylase | 0.0107 | 0.1433 | 0.1433 |
Schistosoma mansoni | thyroid hormone receptor | 0.0139 | 0.1935 | 0.1935 |
Leishmania major | thymidylate kinase-like protein | 0.0141 | 0.1962 | 0.254 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0066 | 0.0063 |
Schistosoma mansoni | hypothetical protein | 0.0654 | 1 | 1 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0045 | 0.0459 | 0.0581 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0061 | 0.0712 | 0.0876 |
Loa Loa (eye worm) | RNA binding protein | 0.0207 | 0.2992 | 0.2992 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0035 | 0.0307 | 0.0307 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0066 | 0.0066 |
Schistosoma mansoni | glycogen phosphorylase | 0.0046 | 0.0479 | 0.0479 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0045 | 0.0459 | 0.2121 |
Plasmodium falciparum | thymidylate kinase | 0.0141 | 0.1962 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.0066 | 0.0016 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0046 | 0.0479 | 0.2227 |
Mycobacterium tuberculosis | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) | 0.0141 | 0.1962 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.0022 | 0.0093 | 0.0052 |
Brugia malayi | TAR-binding protein | 0.0207 | 0.2992 | 0.3792 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0107 | 0.1433 | 0.1433 |
Brugia malayi | RNase H family protein | 0.0022 | 0.0093 | 0.0118 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0531 | 0.0531 |
Echinococcus granulosus | geminin | 0.036 | 0.5393 | 0.5393 |
Trypanosoma brucei | unspecified product | 0.0027 | 0.017 | 0.0155 |
Schistosoma mansoni | phosphoglucomutase | 0.0022 | 0.0093 | 0.0093 |
Echinococcus multilocularis | geminin | 0.036 | 0.5393 | 0.5393 |
Trypanosoma brucei | ribonuclease H1 | 0.0022 | 0.0093 | 0.0052 |
Schistosoma mansoni | thyroid hormone receptor | 0.0139 | 0.1935 | 0.1935 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.005 | 0.0531 | 0.0634 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.0066 | 0.0016 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0112 | 0.15 | 0.1901 |
Schistosoma mansoni | glycogen phosphorylase | 0.0107 | 0.1433 | 0.1433 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.1084 | 0.5396 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0022 | 0.0093 | 0.0052 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0107 | 0.1433 | 0.357 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0066 | 0.0016 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0107 | 0.1433 | 0.1433 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.2992 | 0.2992 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.0316 | 0.0348 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0561 | 0.0561 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0066 | 0.0066 |
Schistosoma mansoni | Smad4 | 0.0035 | 0.0307 | 0.0307 |
Treponema pallidum | ribonuclease H (rnhA) | 0.0022 | 0.0093 | 0.0205 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.0046 | 0.0479 | 0.0566 |
Echinococcus granulosus | ribonuclease H1 | 0.0022 | 0.0093 | 0.0093 |
Schistosoma mansoni | thymidylate kinase | 0.0141 | 0.1962 | 0.1962 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0499 | 0.7566 | 1 |
Brugia malayi | Importin beta-1 subunit | 0.0061 | 0.0712 | 0.0902 |
Toxoplasma gondii | hypothetical protein | 0.0029 | 0.0211 | 0.0822 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0054 | 0.0054 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.1084 | 0.5396 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0046 | 0.0479 | 0.0566 |
Leishmania major | ribonuclease H1, putative | 0.0022 | 0.0093 | 0.0052 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0055 | 0.062 | 0.0753 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0582 | 0.0582 |
Brugia malayi | MH1 domain containing protein | 0.0035 | 0.0307 | 0.0389 |
Brugia malayi | N-terminal motif family protein | 0.0183 | 0.2625 | 0.3327 |
Brugia malayi | RNase H family protein | 0.0022 | 0.0093 | 0.0118 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0052 | 0.0561 | 0.0561 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0032 | 0.0257 | 0.1062 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.15 | 0.15 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0183 | 0.2625 | 0.654 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0034 | 0.0289 | 0.0289 |
Chlamydia trachomatis | thymidylate kinase | 0.0141 | 0.1962 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0129 | 0.1773 | 0.1773 |
Echinococcus multilocularis | thymidine kinase | 0.0249 | 0.3661 | 0.3661 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0085 | 0.1084 | 0.5396 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0289 | 0.0289 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0066 | 0.0066 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.2992 | 0.2992 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0059 | 0.0059 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0316 | 0.1372 |
Treponema pallidum | thymidylate kinase (tmk) | 0.0141 | 0.1962 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0066 | 0.0066 |
Schistosoma mansoni | smad1 5 8 and | 0.0035 | 0.0307 | 0.0307 |
Echinococcus multilocularis | Smad4 | 0.0035 | 0.0307 | 0.0307 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0029 | 0.0211 | 0.0822 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0499 | 0.7566 | 1 |
Onchocerca volvulus | Putative thymidylate kinase | 0.0141 | 0.1962 | 0.4888 |
Leishmania major | importin beta-1 subunit, putative | 0.005 | 0.0531 | 0.0634 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0531 | 0.0531 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.2992 | 0.2992 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0066 | 0.0084 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0035 | 0.0307 | 0.0307 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.2309 | 0.2309 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.1084 | 0.1084 |
Echinococcus granulosus | tar DNA binding protein | 0.0207 | 0.2992 | 0.2992 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0519 | 0.7891 | 0.7891 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Schistosoma mansoni | smad1 5 8 and | 0.0035 | 0.0307 | 0.0307 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Trypanosoma brucei | thymidine kinase | 0.0499 | 0.7566 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0066 | 0.0063 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0499 | 0.7566 | 1 |
Mycobacterium ulcerans | thymidylate kinase | 0.0141 | 0.1962 | 1 |
Plasmodium falciparum | importin beta, putative | 0.0061 | 0.0712 | 0.3449 |
Giardia lamblia | Deoxynucleoside kinase | 0.04 | 0.6027 | 0.7951 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0129 | 0.1773 | 0.1773 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0034 | 0.0289 | 0.0289 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0499 | 0.7566 | 1 |
Echinococcus granulosus | thymidine kinase | 0.0249 | 0.3661 | 0.3661 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0129 | 0.1773 | 0.1773 |
Echinococcus multilocularis | snurportin 1 | 0.0654 | 1 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0289 | 0.1233 |
Onchocerca volvulus | 0.0272 | 0.4014 | 1 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.2992 | 0.2992 |
Giardia lamblia | Ribonuclease H | 0.0022 | 0.0093 | 0.0052 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0066 | 0.0066 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0029 | 0.0211 | 0.0822 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0239 | 0.3497 | 0.3497 |
Echinococcus multilocularis | thymidine kinase | 0.0249 | 0.3661 | 0.3661 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0531 | 0.0531 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0055 | 0.062 | 0.0753 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0035 | 0.0307 | 0.0307 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0141 | 0.1962 | 0.254 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0027 | 0.017 | 0.0155 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0085 | 0.1084 | 0.1084 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0052 | 0.0561 | 0.0561 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0139 | 0.1935 | 0.1935 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0316 | 0.1372 |
Schistosoma mansoni | hypothetical protein | 0.036 | 0.5393 | 0.5393 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0056 | 0.0625 | 0.0625 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0054 | 0.0068 |
Trichomonas vaginalis | ran, putative | 0.0045 | 0.0459 | 0.0539 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0289 | 0.0289 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0141 | 0.1962 | 0.254 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.1084 | 0.1084 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0316 | 0.0316 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0316 | 0.0348 |
Leishmania major | thymidine kinase, putative | 0.0499 | 0.7566 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0181 | 0.0667 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0054 | 0.0054 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0499 | 0.7566 | 1 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0141 | 0.1962 | 0.254 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0027 | 0.017 | 0.0155 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0107 | 0.1433 | 0.1836 |
Entamoeba histolytica | thymidine kinase, putative | 0.0499 | 0.7566 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0181 | 0.0169 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0052 | 0.0561 | 0.0711 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.0066 | 0.0066 |
Leishmania major | GTP-binding protein, putative | 0.0045 | 0.0459 | 0.0539 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0107 | 0.1433 | 0.1433 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0181 | 0.0169 |
Loa Loa (eye worm) | thymidylate kinase | 0.0141 | 0.1962 | 0.1962 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0289 | 0.0289 |
Echinococcus multilocularis | transfer RNA-Ile | 0.0249 | 0.3661 | 0.3661 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0107 | 0.1433 | 0.1836 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0316 | 0.0348 |
Brugia malayi | thymidylate kinase | 0.0141 | 0.1962 | 0.2486 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0163 | 0.2309 | 0.2926 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0054 | 0.0054 |
Schistosoma mansoni | hypothetical protein | 0.0112 | 0.15 | 0.15 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0316 | 0.0348 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0056 | 0.0625 | 0.2992 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0085 | 0.1084 | 0.4983 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0056 | 0.0625 | 0.2992 |
Toxoplasma gondii | thymidylate kinase | 0.0141 | 0.1962 | 1 |
Giardia lamblia | Thymidine kinase | 0.0499 | 0.7566 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0316 | 0.0316 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.0289 | 0.0289 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0316 | 0.0316 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0066 | 0.0016 |
Echinococcus granulosus | smad | 0.0035 | 0.0307 | 0.0307 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0034 | 0.0289 | 0.0289 |
Echinococcus multilocularis | GPCR, family 2 | 0.0052 | 0.0561 | 0.0561 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0207 | 0.2992 | 0.3792 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0531 | 0.0531 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0027 | 0.017 | 0.0155 |
Brugia malayi | RNA, U transporter 1 | 0.0174 | 0.2482 | 0.3145 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0066 | 0.0084 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0561 | 0.0561 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0066 | 0.0016 |
Echinococcus granulosus | thymidine kinase | 0.0249 | 0.3661 | 0.3661 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0035 | 0.0307 | 0.0307 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0316 | 0.0348 |
Brugia malayi | RNase H family protein | 0.0022 | 0.0093 | 0.0118 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0045 | 0.0459 | 0.0539 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0066 | 0.0063 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.0066 | 0.0016 |
Giardia lamblia | Glycogen phosphorylase | 0.0107 | 0.1433 | 0.1836 |
Echinococcus granulosus | glycogen phosphorylase | 0.0107 | 0.1433 | 0.1433 |
Entamoeba histolytica | Thymidylate kinase, putative | 0.0141 | 0.1962 | 0.254 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0289 | 0.0289 |
Entamoeba histolytica | Ran family GTPase | 0.0045 | 0.0459 | 0.0539 |
Echinococcus granulosus | dna polymerase eta | 0.002 | 0.0066 | 0.0066 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0181 | 0.0169 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0056 | 0.0625 | 0.0625 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0066 | 0.0016 |
Echinococcus granulosus | Thymidine kinase 2 mitochondrial | 0.0249 | 0.3661 | 0.3661 |
Schistosoma mansoni | smad | 0.0035 | 0.0307 | 0.0307 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0029 | 0.0037 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0066 | 0.0016 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.2992 | 0.2992 |
Echinococcus granulosus | glycogen phosphorylase | 0.0107 | 0.1433 | 0.1433 |
Mycobacterium leprae | probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) | 0.0141 | 0.1962 | 1 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0045 | 0.0459 | 0.0539 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0141 | 0.1962 | 0.254 |
Loa Loa (eye worm) | TAR-binding protein | 0.0207 | 0.2992 | 0.2992 |
Onchocerca volvulus | 0.0034 | 0.0289 | 0.0721 | |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0056 | 0.0625 | 0.2364 |
Echinococcus granulosus | GPCR family 2 | 0.0052 | 0.0561 | 0.0561 |
Brugia malayi | RNA binding protein | 0.0207 | 0.2992 | 0.3792 |
Echinococcus multilocularis | thymidylate kinase | 0.0141 | 0.1962 | 0.1962 |
Plasmodium vivax | importin-beta 2, putative | 0.0061 | 0.0712 | 0.3449 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0045 | 0.0459 | 0.2121 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0654 | 1 | 1 |
Brugia malayi | Smad1 | 0.0035 | 0.0307 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0561 | 0.0561 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0107 | 0.1433 | 0.1433 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.1084 | 0.5396 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0033 | 0.027 | 0.027 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Brugia malayi | MH1 domain containing protein | 0.0035 | 0.0307 | 0.0389 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0107 | 0.1433 | 0.3981 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0045 | 0.0459 | 0.0459 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0316 | 0.0348 |
Schistosoma mansoni | ran | 0.0045 | 0.0459 | 0.0459 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0046 | 0.0479 | 0.0566 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Schistosoma mansoni | ran | 0.0045 | 0.0459 | 0.0459 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0085 | 0.1084 | 0.5396 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0531 | 0.0531 |
Echinococcus granulosus | Smad4 | 0.0035 | 0.0307 | 0.0307 |
Brugia malayi | MH1 domain containing protein | 0.002 | 0.0059 | 0.0075 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Loa Loa (eye worm) | Smad1 | 0.0035 | 0.0307 | 0.0307 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.1084 | 0.5396 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0107 | 0.1433 | 0.1433 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Trypanosoma brucei | RNA helicase, putative | 0.0218 | 0.3163 | 0.4138 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0163 | 0.2309 | 0.2309 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0029 | 0.0211 | 0.0822 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0316 | 0.0316 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0107 | 0.1433 | 0.1836 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0066 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0141 | 0.1962 | 0.254 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0045 | 0.0459 | 0.0459 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0045 | 0.0459 | 0.0539 |
Wolbachia endosymbiont of Brugia malayi | thymidylate kinase | 0.0141 | 0.1962 | 1 |
Schistosoma mansoni | hypothetical protein | 0.036 | 0.5393 | 0.5393 |
Giardia lamblia | CDC8 | 0.0141 | 0.1962 | 0.254 |
Schistosoma mansoni | thymidine kinase | 0.0249 | 0.3661 | 0.3661 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0531 | 0.0531 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.0289 | 0.1233 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0046 | 0.0479 | 0.2227 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0531 | 0.0531 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0035 | 0.0307 | 0.0307 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0061 | 0.0712 | 0.3449 |
Brugia malayi | carbohydrate phosphorylase | 0.0107 | 0.1433 | 0.1816 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0052 | 0.0561 | 0.0561 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.005 | 0.0531 | 0.0634 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0045 | 0.0459 | 0.2121 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2625 | 0.2625 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0181 | 0.0667 |
Brugia malayi | MH2 domain containing protein | 0.0035 | 0.0307 | 0.0389 |
Schistosoma mansoni | phosphoglucomutase | 0.0022 | 0.0093 | 0.0093 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0066 | 0.0066 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0163 | 0.2309 | 0.2926 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.005 | 0.0531 | 0.0634 |
Onchocerca volvulus | Ribonuclease H1 homolog | 0.0022 | 0.0093 | 0.0232 |
Echinococcus multilocularis | tar DNA binding protein | 0.0207 | 0.2992 | 0.2992 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0022 | 0.0093 | 0.0052 |
Echinococcus granulosus | thymidylate kinase | 0.0141 | 0.1962 | 0.1962 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0027 | 0.017 | 0.0155 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0061 | 0.0712 | 0.0712 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0085 | 0.1084 | 0.5396 |
Brugia malayi | MH2 domain containing protein | 0.0035 | 0.0307 | 0.0389 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0032 | 0.0257 | 0.0262 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0052 | 0.0561 | 0.0561 |
Schistosoma mansoni | hypothetical protein | 0.0141 | 0.1962 | 0.1962 |
Schistosoma mansoni | hypothetical protein | 0.0218 | 0.3163 | 0.3163 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0561 | 0.0561 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0052 | 0.0561 | 0.0561 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0052 | 0.0561 | 0.0711 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0181 | 0.0667 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.1084 | 0.5396 |
Schistosoma mansoni | thymidylate kinase | 0.0141 | 0.1962 | 0.1962 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0054 | 0.0054 |
Echinococcus multilocularis | ribonuclease H1 | 0.0022 | 0.0093 | 0.0093 |
Trichomonas vaginalis | set domain proteins, putative | 0.0272 | 0.4014 | 0.5272 |
Wolbachia endosymbiont of Brugia malayi | ribonuclease HI | 0.0022 | 0.0093 | 0.0205 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0712 | 0.0712 |
Schistosoma mansoni | importin beta-1 | 0.0061 | 0.0712 | 0.0712 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0316 | 0.0348 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0181 | 0.0169 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0035 | 0.0307 | 0.0307 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0316 | 0.04 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0066 | 0.0063 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0066 | 0.0016 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0531 | 0.0673 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0316 | 0.0316 |
Echinococcus multilocularis | smad | 0.0035 | 0.0307 | 0.0307 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0045 | 0.0459 | 0.0459 |
Brugia malayi | Probable ClpP-like protease | 0.0085 | 0.1084 | 0.1373 |
Echinococcus granulosus | importin subunit beta 1 | 0.0061 | 0.0712 | 0.0712 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0316 | 0.0348 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0181 | 0.023 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0107 | 0.1433 | 0.1836 |
Schistosoma mansoni | phosphoglucomutase | 0.0022 | 0.0093 | 0.0093 |
Schistosoma mansoni | smad1 5 8 and | 0.0035 | 0.0307 | 0.0307 |
Brugia malayi | MH2 domain containing protein | 0.0519 | 0.7891 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0519 | 0.7891 | 0.7891 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0045 | 0.0459 | 0.0539 |
Entamoeba histolytica | hypothetical protein | 0.005 | 0.0531 | 0.0634 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0035 | 0.0307 | 0.0307 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0181 | 0.0667 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0066 | 0.0016 |
Plasmodium vivax | thymidylate kinase, putative | 0.0141 | 0.1962 | 1 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0141 | 0.1962 | 0.254 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.0066 | 0.0016 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.0289 | 0.0367 |
Toxoplasma gondii | ribonuclease HI protein | 0.0022 | 0.0093 | 0.0205 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 25 uM | Inhibition of Rap1a protein modification in human K562 cells by Western blot relative to lovastatin | ChEMBL. | 18308574 |
Activity (functional) | = 25 uM | Inhibition of Rap1a protein modification in human K562 cells by Western blot relative to lovastatin | ChEMBL. | 18308574 |
GI50 (functional) | > 100 uM | Growth inhibition of human K562 cells after 24 hrs | ChEMBL. | 18308574 |
GI50 (functional) | > 100 uM | Growth inhibition of human K562 cells after 24 hrs | ChEMBL. | 18308574 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.