Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.1082 | 0.1082 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Onchocerca volvulus | 0.0018 | 0.0229 | 0.0261 | |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0018 | 0.0203 | 0.0203 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.023 | 0.02 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0018 | 0.0229 | 0.0197 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0018 | 0.0229 | 0.0197 |
Onchocerca volvulus | 0.0023 | 0.036 | 0.1627 | |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0743 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.036 | 0.0409 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.3309 | 0.8096 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0018 | 0.0229 | 0.0197 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0018 | 0.0203 | 0.0203 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0023 | 0.036 | 0.183 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0018 | 0.0203 | 0.0203 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0743 | 0.0804 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.0836 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0133 | 0.3835 | 0.792 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0743 | 0.7194 |
Echinococcus multilocularis | nAChR subunit | 0.0018 | 0.0229 | 0.0229 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.1491 | 0.1491 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0743 | 0.1521 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0023 | 0.036 | 0.0744 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0023 | 0.036 | 0.036 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0023 | 0.036 | 0.036 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0023 | 0.036 | 0.0205 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0018 | 0.0203 | 0.042 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0203 | 0.042 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0041 | 0.0944 | 0.5659 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0041 | 0.0944 | 0.5659 |
Schistosoma mansoni | nAChR subunit | 0.0018 | 0.0229 | 0.0472 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0018 | 0.0229 | 0.0197 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.1168 | 0.2412 |
Loa Loa (eye worm) | ACC-1 protein | 0.0018 | 0.0229 | 0.0066 |
Loa Loa (eye worm) | ACC-1 protein | 0.0018 | 0.0229 | 0.0066 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0018 | 0.0229 | 0.0229 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0203 | 0.0203 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0018 | 0.0229 | 0.0229 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0203 | 0.0132 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0203 | 0.0132 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0018 | 0.0229 | 0.0229 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0018 | 0.0229 | 0.0197 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0018 | 0.0229 | 0.0197 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.036 | 0.0409 |
Echinococcus multilocularis | neuroligin | 0.0023 | 0.036 | 0.036 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0203 | 0.0132 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0018 | 0.0203 | 0.042 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0743 | 0.7194 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0426 | 0.0704 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.023 | 0.0474 |
Schistosoma mansoni | acetylcholinesterase | 0.0023 | 0.036 | 0.0744 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.036 | 0.0744 |
Brugia malayi | Carboxylesterase family protein | 0.0133 | 0.3835 | 0.9474 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0203 | 0.0132 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0743 | 0.0743 |
Schistosoma mansoni | nAChR subunit | 0.0018 | 0.0229 | 0.0472 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0018 | 0.0229 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0743 | 0.0804 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0018 | 0.0229 | 0.0229 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0018 | 0.0229 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0018 | 0.0229 | 0.0229 |
Echinococcus granulosus | geminin | 0.0166 | 0.4842 | 0.4842 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.4842 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0018 | 0.0229 | 0.0197 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0023 | 0.036 | 0.036 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0426 | 0.1553 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0018 | 0.0229 | 0.0472 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0743 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0203 | 0.0203 |
Echinococcus granulosus | acetylcholinesterase | 0.0133 | 0.3835 | 0.3835 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0018 | 0.0229 | 0.0197 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.036 | 0.0744 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0203 | 0.0132 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.023 | 0.023 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1491 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0023 | 0.036 | 0.1036 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0203 | 0.0132 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0018 | 0.0229 | 0.0472 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0041 | 0.0944 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0018 | 0.0203 | 0.042 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0203 | 0.0132 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0743 | 0.1535 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.036 | 0.0536 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.036 | 0.0536 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0023 | 0.036 | 0.036 |
Onchocerca volvulus | 0.0018 | 0.0229 | 0.0261 | |
Onchocerca volvulus | 0.0035 | 0.0743 | 0.5596 | |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.023 | 0.0069 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0018 | 0.0203 | 0.0132 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0018 | 0.0229 | 0.0229 |
Onchocerca volvulus | 0.0018 | 0.0229 | 0.0261 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.0133 | 0.3835 | 0.3835 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0743 | 0.0804 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.3309 | 0.8121 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0018 | 0.0229 | 0.0197 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0018 | 0.0229 | 0.0229 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0041 | 0.0944 | 1 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.0836 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0743 | 0.4071 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.1082 | 0.1082 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0018 | 0.0229 | 0.0229 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.3309 | 0.8096 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0023 | 0.036 | 0.036 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0203 | 0.0132 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0203 | 0.042 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0018 | 0.0229 | 0.0229 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0743 | 0.1535 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0743 | 0.0804 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0743 | 0.0804 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0018 | 0.0229 | 0.0229 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0018 | 0.0229 | 0.0229 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0018 | 0.0203 | 0.0203 |
Loa Loa (eye worm) | LGC-31 protein | 0.0018 | 0.0229 | 0.0066 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0018 | 0.0203 | 0.0203 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0743 | 0.0804 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.023 | 0.0474 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0426 | 0.2745 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0018 | 0.0229 | 0.0472 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0203 | 0.0132 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0743 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0203 | 0.0203 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0023 | 0.036 | 0.0744 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1491 | 1 |
Onchocerca volvulus | 0.0023 | 0.036 | 0.1627 | |
Onchocerca volvulus | 0.0023 | 0.036 | 0.1627 | |
Schistosoma mansoni | nAChR subunit | 0.0018 | 0.0229 | 0.0472 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.1082 | 0.1082 |
Echinococcus multilocularis | tumor protein p63 | 0.033 | 1 | 1 |
Onchocerca volvulus | Putative nachr subunit | 0.0018 | 0.0229 | 0.0261 |
Onchocerca volvulus | 0.0035 | 0.0743 | 0.5596 | |
Echinococcus granulosus | neuroligin | 0.0023 | 0.036 | 0.036 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0203 | 0.0132 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0743 | 0.0804 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0743 | 0.4071 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0041 | 0.0944 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0203 | 0.0132 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0743 | 0.1521 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0203 | 0.0132 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0018 | 0.0229 | 0.0472 |
Brugia malayi | ecdysteroid receptor | 0.0018 | 0.0203 | 0.0132 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0.023 | 0.5 |
Echinococcus granulosus | nAChR subunit | 0.0018 | 0.0229 | 0.0229 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1491 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0018 | 0.0229 | 0.0197 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0426 | 0.1553 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0743 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0203 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0426 | 0.3231 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0018 | 0.0229 | 0.0229 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0018 | 0.0229 | 0.0229 |
Onchocerca volvulus | 0.0018 | 0.0229 | 0.0261 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0203 | 0.0132 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0018 | 0.0229 | 0.0229 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0018 | 0.0229 | 0.0229 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.023 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0133 | 0.3835 | 0.3835 |
Schistosoma mansoni | nAChR subunit | 0.0018 | 0.0229 | 0.0472 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0018 | 0.0229 | 0.0229 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1082 | 0.2234 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0018 | 0.0229 | 0.0066 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0743 | 0.4071 |
Onchocerca volvulus | 0.0048 | 0.1168 | 1 | |
Echinococcus granulosus | FTZ F1 alpha | 0.0018 | 0.0203 | 0.0203 |
Brugia malayi | Cation transporter family protein | 0.0018 | 0.0229 | 0.0197 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0018 | 0.0229 | 0.0229 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0743 | 0.4071 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0203 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0743 | 0.1407 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0743 | 0.0804 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1082 | 0.2234 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0018 | 0.0203 | 0.042 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0426 | 0.3231 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.1491 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0743 | 0.1407 |
Schistosoma mansoni | nAChR subunit | 0.0018 | 0.0229 | 0.0472 |
Echinococcus multilocularis | geminin | 0.0166 | 0.4842 | 0.4842 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0743 | 0.1407 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1491 | 0.3079 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.014 | 0.404 | 0.8342 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0018 | 0.0229 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.3835 | 0.9467 |
Brugia malayi | steroid hormone receptor | 0.0018 | 0.0203 | 0.0132 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0133 | 0.3835 | 0.9467 |
Echinococcus multilocularis | acetylcholinesterase | 0.0133 | 0.3835 | 0.3835 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0743 | 0.4071 |
Schistosoma mansoni | gliotactin | 0.0023 | 0.036 | 0.0744 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0203 | 0.0203 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.1082 | 0.229 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.036 | 0.0409 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0041 | 0.0944 | 0.0944 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.4842 | 1 |
Brugia malayi | hypothetical protein | 0.0023 | 0.036 | 0.0536 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0426 | 0.3815 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0018 | 0.0229 | 0.0472 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0743 | 0.7194 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0203 | 0.0203 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0018 | 0.0203 | 0.0132 |
Echinococcus granulosus | acetylcholinesterase | 0.0133 | 0.3835 | 0.3835 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.036 | 0.0409 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.1491 | 0.1491 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0743 | 0.0743 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0018 | 0.0203 | 0.042 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0018 | 0.0229 | 0.0066 |
Brugia malayi | Carboxylesterase family protein | 0.0133 | 0.3835 | 0.9474 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1168 | 0.2515 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0018 | 0.0203 | 0.042 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0203 | 0.0132 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0203 | 0.0203 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0018 | 0.0203 | 0.0132 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0018 | 0.0229 | 0.0229 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0023 | 0.036 | 0.036 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0136 | 0.3917 | 0.3917 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0743 | 0.1407 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0018 | 0.0203 | 0.042 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0743 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0743 | 0.7194 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0743 | 0.1521 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0018 | 0.0229 | 0.0472 |
Brugia malayi | Cation transporter family protein | 0.0018 | 0.0229 | 0.0197 |
Onchocerca volvulus | 0.0018 | 0.0229 | 0.0261 | |
Brugia malayi | acetyltransferase, GNAT family protein | 0.014 | 0.404 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0018 | 0.0203 | 0.042 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.014 | 0.404 | 0.404 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0018 | 0.0229 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.036 | 0.0409 |
Echinococcus granulosus | carboxylesterase 5A | 0.0133 | 0.3835 | 0.3835 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0426 | 0.3815 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0018 | 0.0229 | 0.0229 |
Onchocerca volvulus | 0.0035 | 0.0743 | 0.5596 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0023 | 0.036 | 0.0744 |
Onchocerca volvulus | 0.0018 | 0.0229 | 0.0261 | |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0018 | 0.0229 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.036 | 0.0409 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.1491 | 0.1976 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0018 | 0.0229 | 0.0229 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0018 | 0.0229 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.036 | 0.0409 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.036 | 0.0409 |
Schistosoma mansoni | nAChR subunit | 0.0018 | 0.0229 | 0.0472 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0023 | 0.036 | 0.183 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.1491 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.1082 | 0.1082 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0203 | 0.0132 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0743 | 0.1521 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0018 | 0.0229 | 0.0197 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0743 | 0.1407 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0743 | 0.7194 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0018 | 0.0229 | 0.0197 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.1082 | 0.2392 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0018 | 0.0203 | 0.0203 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.036 | 0.0536 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0018 | 0.0229 | 0.0229 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0222 | 0.6614 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.023 | 0.023 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0743 | 0.7194 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0018 | 0.0229 | 0.0066 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0743 | 0.4071 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0743 | 0.1407 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0743 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0426 | 0.0579 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0743 | 0.1407 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0018 | 0.0203 | 0.0203 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0743 | 0.4071 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0018 | 0.0229 | 0.0197 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0743 | 0.0804 |
Onchocerca volvulus | 0.0023 | 0.036 | 0.1627 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0743 | 0.7194 |
Loa Loa (eye worm) | carboxylesterase | 0.0133 | 0.3835 | 0.9467 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Brugia malayi | Cation transporter family protein | 0.0018 | 0.0229 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.3835 | 0.9467 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0203 | 0.042 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0203 | 0.042 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0023 | 0.036 | 0.0205 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0018 | 0.0229 | 0.0066 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1082 | 0.2234 |
Schistosoma mansoni | coup transcription factor | 0.0018 | 0.0203 | 0.042 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0743 | 0.1407 |
Schistosoma mansoni | nAChR subunit | 0.0018 | 0.0229 | 0.0472 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0023 | 0.036 | 0.0205 |
Onchocerca volvulus | 0.0023 | 0.036 | 0.1627 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0426 | 0.3815 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0018 | 0.0229 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.0836 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0018 | 0.0229 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.036 | 0.0409 |
Loa Loa (eye worm) | acetyltransferase | 0.014 | 0.404 | 1 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0018 | 0.0229 | 0.0197 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0203 | 0.0203 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.036 | 0.0536 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1491 | 0.3079 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0229 | 0.0066 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0203 | 0.0203 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0018 | 0.0229 | 0.0197 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Relative activity (functional) | = 6 | Relative Analgesic activity of compound to the N-methyl homologue assayed by the mouse hot-plate method | ChEMBL. | 7057419 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.