Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | adenosine monophosphate deaminase 3 | Starlite/ChEMBL | References |
Homo sapiens | adenosine monophosphate deaminase 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | AMP deaminase | 0.019 | 1 | 1 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.019 | 1 | 0.5 |
Leishmania major | AMP deaminase, putative | 0.019 | 1 | 0.5 |
Leishmania major | adenosine monophosphate deaminase, putative,AMP deaminase, putative | 0.019 | 1 | 0.5 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.019 | 1 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.019 | 1 | 0.5 |
Entamoeba histolytica | AMP deaminase, putative | 0.019 | 1 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.019 | 1 | 0.5 |
Echinococcus multilocularis | AMP deaminase 2 | 0.019 | 1 | 0.5 |
Leishmania major | AMP deaminase, putative,amp deaminase-like protein | 0.019 | 1 | 0.5 |
Echinococcus granulosus | AMP deaminase 2 | 0.019 | 1 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.019 | 1 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.019 | 1 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.019 | 1 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.019 | 1 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.019 | 1 | 0.5 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.019 | 1 | 0.5 |
Onchocerca volvulus | AMP deaminase 2 homolog | 0.019 | 1 | 0.5 |
Leishmania major | AMP deaminase, putative,adenosine monophosphate deaminase-like protein | 0.019 | 1 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.019 | 1 | 0.5 |
Toxoplasma gondii | AMP deaminase | 0.019 | 1 | 0.5 |
Plasmodium vivax | adenosine/AMP deaminase, putative | 0.019 | 1 | 0.5 |
Schistosoma mansoni | AMP deaminase | 0.019 | 1 | 0.5 |
Entamoeba histolytica | AMP deaminase, putative | 0.019 | 1 | 0.5 |
Plasmodium falciparum | AMP deaminase, putative | 0.019 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 0.41 uM | Inhibition of recombinant human E-type adenylate deaminase | ChEMBL. | 11170651 |
Ki (binding) | = 0.41 uM | Evaluated for the inhibition of porcine heart or human L-type Adenosine 5'-monophosphate deaminase (AMPDA) | ChEMBL. | 10780906 |
Ki (binding) | = 0.41 uM | Inhibition of recombinant human E-type adenylate deaminase | ChEMBL. | 11170651 |
Ki (binding) | = 0.41 uM | Evaluated for the inhibition of porcine heart or human L-type Adenosine 5'-monophosphate deaminase (AMPDA) | ChEMBL. | 10780906 |
Ki (binding) | > 1000 uM | Evaluated for the inhibition of calf intestinal Adenosine deaminase (ADA) | ChEMBL. | 10780906 |
Ki (binding) | > 1000 uM | Evaluated for the inhibition of calf intestinal Adenosine deaminase (ADA) | ChEMBL. | 10780906 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.