Detailed information for compound 517702

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 273.761 | Formula: C15H16ClN3
  • H donors: 1 H acceptors: 2 LogP: 2.79 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)c1nc(C)nc2c1CCNCC2
  • InChi: 1S/C15H16ClN3/c1-10-18-14-7-9-17-8-6-13(14)15(19-10)11-2-4-12(16)5-3-11/h2-5,17H,6-9H2,1H3
  • InChiKey: ZUEGJLFXFLMUCB-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus hypothetical protein Get druggable targets OG5_144688 All targets in OG5_144688
Echinococcus multilocularis conserved hypothetical protein Get druggable targets OG5_144688 All targets in OG5_144688
Brugia malayi Serotonin receptor Get druggable targets OG5_135430 All targets in OG5_135430

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma cruzi cytochrome P450, putative 0.0052 0.0262 0.0265
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0092 0.0536 0.053
Loa Loa (eye worm) hypothetical protein 0.0039 0.0172 0.0436
Leishmania major hypothetical protein, conserved 0.0024 0.0068 0.0063
Onchocerca volvulus 0.0057 0.0295 0.085
Treponema pallidum thioredoxin reductase (trxB) 0.0104 0.0622 0.2276
Loa Loa (eye worm) hypothetical protein 0.002 0.0037 0.0079
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0048 0.0041
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0191 0.0184
Schistosoma mansoni hypothetical protein 0.0076 0.0426 0.042
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0012 0.0004
Schistosoma mansoni cellular tumor antigen P53 0.0105 0.0624 0.0618
Loa Loa (eye worm) norepinephrine transporter 0.0247 0.1612 0.424
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1032 0.7035 0.7327
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0108 0.0203
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1969 0.3829
Echinococcus multilocularis survival motor neuron protein 1 0.05 0.3361 0.3357
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.0426 0.042
Echinococcus granulosus geminin 0.0359 0.238 0.2375
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0117 0.0292
Brugia malayi Pre-SET motif family protein 0.0441 0.2951 0.6912
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0037 0.003
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0091 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0255 0.049
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0104 0.0622 0.19
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.067 0.2462
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0109 0.0657 0.0676
Trypanosoma cruzi target of rapamycin kinase 3 0.0076 0.0424 0.0433
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0393 0.2618 0.2721
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0048 0.0109
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0189 0.0182
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.067 0.069
Brugia malayi Cytochrome P450 family protein 0.0095 0.0557 0.1303
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0012 0.0004
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.067 0.2578
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0121 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0037 0.003
Echinococcus multilocularis fmrfamide receptor 0.0076 0.0426 0.042
Schistosoma mansoni DNA polymerase eta 0.002 0.0037 0.003
Schistosoma mansoni hypothetical protein 0.0042 0.0189 0.0182
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0104 0.0622 0.19
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0037 0.003
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0048 0.0041
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0104 0.0622 0.1763
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.003 0.0109 0.0251
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.067 0.1907
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0034 0.0134 0.0302
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.0911 0.3346
Echinococcus granulosus glutamate synthase 0.0104 0.0622 0.0615
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0037 0.003
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0017 0.0016 0.001
Echinococcus multilocularis G-protein coupled receptor, putative 0.0076 0.0426 0.042
Trichomonas vaginalis set domain proteins, putative 0.0502 0.3372 0.656
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0104 0.0622 0.1453
Echinococcus granulosus tumor protein p63 0.0715 0.4845 0.4842
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Echinococcus granulosus allatostatin A receptor 0.0076 0.0426 0.042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.0426 0.042
Mycobacterium leprae putative cytochrome p450 0.0034 0.0134 0.0318
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.003 0.0051
Giardia lamblia DNA repair protein RAD52 0.038 0.2527 0.9648
Leishmania major DNA polymerase eta, putative 0.002 0.0037 0.003
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0037 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0048 0.0109
Echinococcus granulosus tyrosine protein kinase Src42A 0.0039 0.0167 0.016
Loa Loa (eye worm) solute carrier family 6 member 4 0.0247 0.1612 0.424
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0012 0.0005
Echinococcus granulosus neuropeptide FF receptor 2 0.0076 0.0426 0.042
Mycobacterium ulcerans endonuclease IV 0.0084 0.0479 0.1337
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0085 0.0486 0.048
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0189 0.0182
Echinococcus granulosus mitogen activated protein kinase 0.0109 0.0657 0.065
Onchocerca volvulus 0.0247 0.1612 0.4766
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0108 0.0299
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0295 0.0761
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0059 0.0108
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0393 0.2618 1
Echinococcus multilocularis dna polymerase eta 0.002 0.0037 0.003
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0076 0.0426 0.1107
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.067 0.0663
Onchocerca volvulus 0.0076 0.0426 0.124
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0357 0.2369 0.7003
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0269 0.0272
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0066 0.0059
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0104 0.0622 0.2276
Loa Loa (eye worm) phosphatidylinositol 3 0.0095 0.0558 0.1456
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0108 0.0299
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Echinococcus granulosus thioredoxin glutathione reductase 0.048 0.3221 0.3216
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0321 0.0314
Giardia lamblia Fructose-bisphosphate aldolase 0.0299 0.1969 0.749
Schistosoma mansoni biogenic amine (5HT) receptor 0.0201 0.1288 0.1282
Giardia lamblia NADH oxidase lateral transfer candidate 0.0393 0.2618 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.003 0.0051
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0042 0.0188 0.0188
Schistosoma mansoni sulfide quinone reductase 0.0104 0.0622 0.0615
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0104 0.0622 0.1204
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0393 0.2618 0.8121
Echinococcus granulosus histone lysine methyltransferase setb 0.0081 0.0462 0.0456
Plasmodium vivax ferredoxin, putative 0.0024 0.0068 0.0176
Echinococcus multilocularis sex peptide receptor 0.0076 0.0426 0.042
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0295 0.0761
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0034 0.0134 0.0302
Onchocerca volvulus 0.0076 0.0426 0.124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0255 0.049
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0037 0.003
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0109 0.0657 0.1716
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.001 0.0003
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0037 0.0082
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0191 0.0184
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.118 0.8062 0.8399
Schistosoma mansoni 60S ribosomal protein L21 0.0016 0.001 0.0003
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0085 0.0486 0.1136
Brugia malayi neuropeptide F receptor 0.0076 0.0426 0.0995
Brugia malayi hypothetical protein 0.0076 0.0426 0.0995
Loa Loa (eye worm) blistered cuticle protein 3 0.0079 0.0449 0.1169
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0037 0.003
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0086 0.0492 0.1149
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0076 0.0426 0.042
Brugia malayi hypothetical protein 0.0034 0.0138 0.032
Loa Loa (eye worm) hypothetical protein 0.0377 0.2507 0.6604
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0076 0.0426 0.042
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0154 0.0148
Loa Loa (eye worm) hypothetical protein 0.0104 0.0622 0.1624
Brugia malayi putative neuropeptide receptor 0.0076 0.0426 0.0995
Schistosoma mansoni fkbp-rapamycin associated protein 0.0018 0.0025 0.0018
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0104 0.0622 0.0639
Schistosoma mansoni neuropeptide receptor 0.0076 0.0426 0.042
Echinococcus granulosus hyperpolarization activated cyclic 0.0023 0.0059 0.0052
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0042 0.0188 0.0182
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0141 0.0327
Trichomonas vaginalis Ferredoxin 3 0.0024 0.0068 0.0126
Schistosoma mansoni loxhd1 0.0042 0.0189 0.0182
Toxoplasma gondii ferredoxin, putative 0.0024 0.0068 0.0176
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0034 0.0134 0.0131
Loa Loa (eye worm) TYRA-2 protein 0.0076 0.0426 0.1107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0293 0.0564
Echinococcus granulosus ferredoxin 0.0024 0.0068 0.0062
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0421 0.281 0.2922
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0034 0.0134 0.0302
Schistosoma mansoni cpg binding protein 0.0035 0.0143 0.0136
Schistosoma mansoni hypothetical protein 0.0016 0.0012 0.0005
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0012 0.0005
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.018 0.0178
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0256 0.1668 0.4901
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0048 0.0117
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0085 0.0486 0.048
Loa Loa (eye worm) hypothetical protein 0.05 0.3361 0.886
Echinococcus multilocularis serotonin receptor 0.0201 0.1288 0.1282
Leishmania major protein kinase, putative 0.0017 0.0016 0.0008
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0025 0.0049
Chlamydia trachomatis endonuclease IV 0.0084 0.0479 0.1611
Loa Loa (eye worm) hypothetical protein 0.0104 0.0617 0.1612
Brugia malayi nuclear hormone receptor 0.0021 0.0048 0.0109
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0012 0.0005
Echinococcus granulosus potassium voltage gated channel subfamily H 0.003 0.0109 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0389 0.0751
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0048 0.0041
Loa Loa (eye worm) hypothetical protein 0.0045 0.0214 0.0549
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0032 0.0121 0.0117
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.003 0.0051
Brugia malayi RE15519p 0.0076 0.0426 0.0995
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0109
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0048 0.0041
Brugia malayi Dopamine receptor protein 1 0.0076 0.0426 0.0995
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0059 0.0108
Schistosoma mansoni biogenic amine receptor 0.0076 0.0426 0.042
Brugia malayi follicle stimulating hormone receptor 0.0563 0.3793 0.8885
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0191 0.0184
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0095 0.0558 0.0573
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0034 0.0134 0.0416
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0167 0.016
Brugia malayi hypothetical protein 0.0104 0.0618 0.1445
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0104 0.0622 0.193
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.0426 0.042
Brugia malayi Cyclic-nucleotide gated cation channel 0.0023 0.0059 0.0134
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0066 0.0059
Trichomonas vaginalis Ferredoxin 6 0.0024 0.0068 0.0126
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1032 0.7035 0.7327
Brugia malayi Dopamine receptor protein 2 0.0076 0.0426 0.0995
Chlamydia trachomatis thioredoxin reductase 0.0104 0.0622 0.2169
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1181 0.2292
Schistosoma mansoni glutamate synthase 0.0104 0.0622 0.0615
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0757 0.5138 1
Schistosoma mansoni adrenodoxin 0.0024 0.0068 0.0062
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.1249 0.2427
Onchocerca volvulus 0.0057 0.0295 0.085
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.067 0.2578
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0048 0.0109
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0112 0.0258
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0048 0.0109
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0024 0.0068 0.0176
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0084 0.0479 0.1488
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0076 0.0426 0.042
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.018 0.0173
Schistosoma mansoni hypothetical protein 0.0024 0.0066 0.0059
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0109 0.0657 0.0676
Echinococcus granulosus tm gpcr rhodopsin 0.0076 0.0426 0.042
Schistosoma mansoni hypothetical protein 0.0359 0.238 0.2375
Loa Loa (eye worm) hypothetical protein 0.0028 0.0091 0.0221
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0076 0.0426 0.042
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0046 0.0104
Onchocerca volvulus 0.0076 0.0426 0.124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0255 0.049
Echinococcus granulosus intermediate filament protein 0.0057 0.0295 0.0288
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0048 0.0041
Onchocerca volvulus 0.0042 0.0191 0.0541
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0189 0.0182
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0037 0.0158 0.0156
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0084 0.0479 0.1119
Echinococcus multilocularis mitogen activated protein kinase 0.0109 0.0657 0.065
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0035 0.0141 0.0134
Echinococcus granulosus serine protein kinase ATM 0.0018 0.0025 0.0018
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0042 0.0191 0.0184
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0039 0.0173 0.0172
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0108 0.0648 0.249
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0048 0.0109
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0042 0.0188 0.0438
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0109 0.0657 0.0676
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0034 0.0134 0.0416
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.025 0.1626 0.1621
Echinococcus multilocularis fmrfamide receptor 0.0076 0.0426 0.042
Loa Loa (eye worm) TK protein kinase 0.0031 0.0114 0.0283
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0009 0.0002
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0048 0.0109
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0039 0.0167 0.016
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0059 0.0052
Brugia malayi Serotonin receptor 0.0076 0.0426 0.0995
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0393 0.2618 0.8121
Schistosoma mansoni polycystin 1-related 0.0042 0.0189 0.0182
Treponema pallidum quinoline 2-oxidoreductase 0.012 0.0732 0.2702
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0023 0.0059 0.0052
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0042 0.0188 0.055
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0048 0.0041
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0104 0.0622 0.1204
Brugia malayi phosphofructokinase 0.0111 0.067 0.1566
Trichomonas vaginalis conserved hypothetical protein 0.004 0.018 0.0343
Brugia malayi hypothetical protein 0.0076 0.0426 0.0995
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0269 0.0801
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1969 0.3829
Loa Loa (eye worm) hypothetical protein 0.004 0.018 0.0456
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0104 0.0622 0.1453
Trypanosoma brucei electron transfer protein, putative 0.0024 0.0068 0.0063
Mycobacterium ulcerans monoxygenase 0.0104 0.0622 0.1763
Echinococcus granulosus RUN 0.0042 0.0189 0.0182
Treponema pallidum oxidoreductase 0.0104 0.0622 0.2276
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.067 0.1751
Schistosoma mansoni rab6-interacting 0.0042 0.0189 0.0182
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0032 0.0121 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0016 0.001
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0104 0.0622 0.19
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0024 0.0068 0.0176
Schistosoma mansoni hypothetical protein 0.0085 0.0486 0.048
Treponema pallidum hypothetical protein 0.0123 0.0751 0.2779
Schistosoma mansoni ap endonuclease 0.0019 0.0033 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0289 0.0556
Brugia malayi hypothetical protein 0.0042 0.0189 0.0438
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0104 0.0622 0.2218
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1181 0.2292
Brugia malayi 6-phosphofructokinase 0.0111 0.067 0.1566
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0034 0.0134 0.0416
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0072 0.0399 0.0407
Loa Loa (eye worm) melatonin receptor type 1A 0.0076 0.0426 0.1107
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0024 0.0068 0.0106
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0034 0.0134 0.0416
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0048 0.0041
Echinococcus multilocularis neuropeptides capa receptor 0.0076 0.0426 0.042
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0393 0.2618 0.2613
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0048 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0037 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1181 0.2292
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0282 0.1852 0.4336
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0076 0.0426 0.042
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0048 0.0109
Echinococcus multilocularis cpg binding protein 0.0035 0.0143 0.0136
Schistosoma mansoni amine GPCR 0.0076 0.0426 0.042
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0076 0.0426 0.042
Trichomonas vaginalis Ferredoxin 7 0.0024 0.0068 0.0126
Echinococcus granulosus neuropeptide receptor 0.0076 0.0426 0.042
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0109 0.0102
Echinococcus granulosus neuropeptide s receptor 0.0579 0.3902 0.3898
Onchocerca volvulus 0.0076 0.0426 0.124
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0034 0.0134 0.0302
Entamoeba histolytica hypothetical protein 0.0108 0.0648 0.249
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0042 0.0191 0.0184
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0012 0.0024
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0104 0.0622 0.1204
Giardia lamblia Glutamate synthase 0.0104 0.0622 0.2276
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1402 0.9598 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0076 0.0426 0.042
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.067 0.2406
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0042 0.0191 0.0479
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0109
Echinococcus granulosus tyrosine protein kinase HCK 0.0031 0.0114 0.0107
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0033 0.0035
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0034 0.0134 0.0416
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0012 0.0013
Echinococcus granulosus mitogen activated protein kinase 11 0.0421 0.281 0.2805
Schistosoma mansoni cpg binding protein 0.0035 0.0143 0.0136
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0108 0.0203
Brugia malayi PHD-finger family protein 0.0027 0.0089 0.0204
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0024 0.0068 0.0213
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0042 0.0191 0.0184
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0269 0.0272
Brugia malayi hypothetical protein 0.0042 0.0189 0.0438
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0012 0.0005
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0037 0.003
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0037 0.003
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0034 0.0134 0.0302
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0076 0.0426 0.124
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0133 0.0127
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0048 0.0109
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0377 0.2507 0.5872
Trichomonas vaginalis apoptosis inducing factor, putative 0.0104 0.0622 0.1204
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0048 0.0041
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0072 0.0399 0.0931
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0109 0.0102
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0269 0.0272
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0393 0.2618 0.2613
Schistosoma mansoni apoptosis regulator bax 0.0085 0.0486 0.048
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.067 0.069
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0042 0.0188 0.0188
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0076 0.0426 0.042
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0104 0.0622 0.0615
Brugia malayi N-terminal motif family protein 0.0195 0.1249 0.2924
Brugia malayi Cytochrome P450 family protein 0.0052 0.0262 0.0611
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0072 0.0065
Brugia malayi GnHR receptor homolog 0.0076 0.0426 0.0995
Brugia malayi Serotonin receptor 0.0632 0.4268 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0399 0.0407
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1181 0.2292
Brugia malayi Pre-SET motif family protein 0.0064 0.0342 0.0797
Echinococcus granulosus neuropeptide Y receptor 0.0076 0.0426 0.042
Brugia malayi ecdysteroid receptor 0.0021 0.0048 0.0109
Brugia malayi hypothetical protein 0.0076 0.0426 0.0995
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0076 0.0426 0.042
Trypanosoma brucei protein kinase, putative 0.0109 0.0657 0.0676
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0076 0.0426 0.042
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0085 0.0486 0.048
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0037 0.003
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0393 0.2618 0.8128
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0048 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0423 0.0817
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0091 0.0084
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0189 0.0551
Echinococcus multilocularis allatostatin A receptor 0.0076 0.0426 0.042
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0034 0.0134 0.0302
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0095 0.0558 0.0551
Echinococcus multilocularis dnaJ subfamily B 0.0447 0.2991 0.2986
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0042 0.0188 0.055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0389 0.0751
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0421 0.281 0.2922
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0037 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.1852 0.36
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0037 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.0426 0.042
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0039 0.0167 0.016
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0076 0.0424 0.0433
Echinococcus granulosus nuclear factor of activated T cells 5 0.008 0.0457 0.045
Echinococcus granulosus cytochrome P450 2K1 0.0034 0.0134 0.0127
Plasmodium vivax ferrodoxin reductase, putative 0.0104 0.0622 0.19
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0037 0.0049
Echinococcus granulosus g-protein coupled receptor 0.0076 0.0426 0.042
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Trypanosoma cruzi NADH dehydrogenase, putative 0.0104 0.0622 0.0639
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0039 0.0167 0.016
Echinococcus multilocularis geminin 0.0359 0.238 0.2375
Echinococcus granulosus serotonin receptor 0.0076 0.0426 0.042
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0024 0.0068 0.0063
Trypanosoma cruzi cytochrome P450, putative 0.0052 0.0262 0.0265
Trichomonas vaginalis glutamate synthase, putative 0.0104 0.0622 0.1204
Echinococcus multilocularis expressed conserved protein 0.0017 0.0016 0.001
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0606 0.1417
Echinococcus granulosus sex peptide receptor 0.0076 0.0426 0.042
Mycobacterium ulcerans electron transfer protein 0.0024 0.0068 0.0106
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0076 0.0426 0.042
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0037 0.0114
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0379 0.252 0.5902
Loa Loa (eye worm) hypothetical protein 0.0072 0.0401 0.1041
Loa Loa (eye worm) hypothetical protein 0.0042 0.0191 0.0488
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0037 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.118 0.8062 0.8399
Echinococcus granulosus tachykinin peptides receptor 99D 0.0076 0.0426 0.042
Echinococcus granulosus fmrfamide receptor 0.0076 0.0426 0.042
Echinococcus multilocularis g protein coupled receptor 0.0076 0.0426 0.042
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0108 0.0299
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0121 0.0228
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0104 0.0622 0.1204
Schistosoma mansoni zinc finger protein 0.0022 0.0051 0.0044
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0095 0.0558 0.0573
Schistosoma mansoni disulfide oxidoreductase 0.0104 0.0622 0.0615
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0104 0.0622 0.0615
Echinococcus multilocularis neuropeptide s receptor 0.0579 0.3902 0.3898
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0052 0.0163
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0191 0.0443
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0033 0.0026
Echinococcus multilocularis G protein coupled receptor 139 0.0076 0.0426 0.042
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0095 0.0558 0.0573
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0191 0.0557
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0393 0.2618 0.2721
Toxoplasma gondii NADPH-glutathione reductase 0.0393 0.2618 0.8121
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.0426 0.042
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0034 0.0134 0.0302
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0189 0.0481
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0072 0.0399 0.0392
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0012 0.0024
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0037 0.003
Echinococcus granulosus peptide allatostatin:somatostatin 0.0076 0.0426 0.042
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0104 0.0622 0.1763
Echinococcus multilocularis voltage gated potassium channel 0.003 0.0109 0.0102
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.018 0.0173
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0034 0.0134 0.0131
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0104 0.0622 0.2276
Echinococcus granulosus lamin dm0 0.0057 0.0295 0.0288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0558 0.108
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0037 0.0158 0.0156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.0426 0.042
Onchocerca volvulus 0.0076 0.0426 0.124
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.0426 0.042
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0045 0.0211 0.0211
Brugia malayi G protein-coupled receptor F59B2.13 0.0076 0.0426 0.0995
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Loa Loa (eye worm) hypothetical protein 0.0071 0.0393 0.1021
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0086 0.0492 0.0486
Schistosoma mansoni voltage-gated potassium channel 0.0093 0.0542 0.0535
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0024 0.0068 0.0106
Leishmania major DNA polymerase kappa, putative 0.002 0.0037 0.003
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0018 0.0025 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0289 0.0556
Echinococcus granulosus mitogen activated protein kinase 3 0.0109 0.0657 0.065
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0657 0.1272
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0191 0.0184
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.0426 0.042
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0024 0.0068 0.0157
Brugia malayi intermediate filament protein 0.0057 0.0295 0.0687
Brugia malayi Uncoordinated protein 44 0.0016 0.0009 0.0017
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0042 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Loa Loa (eye worm) hypothetical protein 0.0081 0.0462 0.1204
Echinococcus granulosus dna polymerase kappa 0.002 0.0037 0.003
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0393 0.2618 0.8121
Trypanosoma cruzi hypothetical protein, conserved 0.0104 0.0622 0.0639
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0018 0.0025 0.0017
Loa Loa (eye worm) apoptosis regulator protein 0.0085 0.0486 0.1267
Schistosoma mansoni hypothetical protein 0.0085 0.0486 0.048
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0657 0.065
Brugia malayi 6-phosphofructokinase 0.0111 0.0671 0.1568
Loa Loa (eye worm) hypothetical protein 0.0042 0.0191 0.0486
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0191 0.0184
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0104 0.0622 0.0615
Brugia malayi G-protein coupled receptor 0.0076 0.0426 0.0995
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.003 0.0109 0.0102
Loa Loa (eye worm) thioredoxin reductase 0.048 0.3221 0.849
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0104 0.0622 0.1763
Echinococcus multilocularis g protein coupled receptor 0.0076 0.0426 0.042
Leishmania major cytochrome p450-like protein 0.0034 0.0134 0.0131
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0262 0.0675
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0104 0.0622 0.1204
Toxoplasma gondii thioredoxin reductase 0.048 0.3221 1
Loa Loa (eye worm) hypothetical protein 0.0247 0.1612 0.424
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.1852 0.36
Trypanosoma cruzi hypothetical protein, conserved 0.0104 0.0622 0.0639
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1181 0.2292
Toxoplasma gondii cytochrome p450 superfamily protein 0.0034 0.0134 0.038
Echinococcus multilocularis neuropeptide FF receptor 2 0.0076 0.0426 0.042
Loa Loa (eye worm) hypothetical protein 0.0042 0.0188 0.048
Plasmodium falciparum thioredoxin reductase 0.0393 0.2618 0.8121
Echinococcus multilocularis glutamate synthase 0.0104 0.0622 0.0615
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0048 0.0109
Schistosoma mansoni tyrosine kinase 0.0039 0.0167 0.016
Echinococcus granulosus mitogen activated protein kinase 14 0.0421 0.281 0.2805
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0077 0.0432 0.0834
Loa Loa (eye worm) hypothetical protein 0.0042 0.0191 0.0486
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0034 0.0134 0.0131
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.0426 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0293 0.0564
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0104 0.0622 0.0615
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1969 0.3829
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0289 0.1897 0.4441
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.0426 0.042
Onchocerca volvulus 0.0104 0.0617 0.1808
Loa Loa (eye worm) G-protein coupled receptor 0.0076 0.0426 0.1107
Trichomonas vaginalis Ferredoxin 2 0.0024 0.0068 0.0126
Echinococcus multilocularis mitogen activated protein kinase 11 0.0421 0.281 0.2805
Trypanosoma cruzi adrenodoxin precursor, putative 0.0024 0.0068 0.0063
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0109 0.0657 0.2009
Onchocerca volvulus Glucosylceramidase homolog 0.0185 0.1181 0.3483
Brugia malayi isocitrate dehydrogenase 0.0016 0.0012 0.0024
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0167 0.016
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0012 0.0005
Schistosoma mansoni hypothetical protein 0.0016 0.0012 0.0005
Trypanosoma brucei unspecified product 0.002 0.0037 0.003
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.0622 0.193
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0393 0.2618 1
Schistosoma mansoni hypothetical protein 0.0016 0.0012 0.0005
Echinococcus multilocularis thioredoxin glutathione reductase 0.048 0.3221 0.3216
Schistosoma mansoni cpg binding protein 0.0031 0.0117 0.011
Trypanosoma cruzi trypanothione reductase, putative 0.0393 0.2618 0.2721
Schistosoma mansoni lipoxygenase 0.0174 0.1107 0.1101
Giardia lamblia GTOR 0.0095 0.0558 0.203
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0076 0.0426 0.1107
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0095 0.0558 0.2131
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0059 0.0052
Trypanosoma brucei cytochrome P450, putative 0.0052 0.0262 0.0265
Loa Loa (eye worm) hypothetical protein 0.0247 0.1612 0.424
Leishmania major hypothetical protein, conserved 0.0104 0.0622 0.0639
Schistosoma mansoni hypothetical protein 0.0034 0.0134 0.0127
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0441 0.2951 0.7777
Loa Loa (eye worm) hypothetical protein 0.0022 0.0052 0.0121
Echinococcus multilocularis serotonin receptor 0.0201 0.1288 0.1282
Echinococcus granulosus survival motor neuron protein 1 0.05 0.3361 0.3357
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.067 0.069
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0048 0.0041
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0145 0.09 0.2794
Echinococcus multilocularis serotonin transporter 0.0247 0.1612 0.1606
Leishmania major trypanothione reductase 0.048 0.3221 0.335
Onchocerca volvulus 0.0105 0.0624 0.1829
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0048 0.0041
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0104 0.0622 0.0639
Plasmodium vivax glutathione reductase, putative 0.048 0.3221 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0037 0.0064
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0108 0.0299
Echinococcus multilocularis neuropeptide receptor 0.0076 0.0426 0.042
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.067 0.0663
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0034 0.0134 0.0131
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0563 0.3793 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0076 0.0426 0.042
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0657 0.1272
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0076 0.0426 0.042
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0034 0.0134 0.0416
Leishmania major C-8 sterol isomerase-like protein 0.0377 0.2507 0.2606
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0076 0.0426 0.1107
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0076 0.0426 0.0995
Loa Loa (eye worm) hypothetical protein 0.0042 0.0191 0.0486
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0048 0.0041
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0104 0.0622 0.0639
Schistosoma mansoni tyrosine kinase 0.0039 0.0167 0.016
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.0426 0.042
Loa Loa (eye worm) hypothetical protein 0.0035 0.0141 0.0356
Schistosoma mansoni hypothetical protein 0.0359 0.238 0.2375
Loa Loa (eye worm) serotonin transporter b 0.0247 0.1612 0.424
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0032 0.0121 0.0114
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0104 0.0622 0.193
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.0426 0.042
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0109 0.0657 0.0676
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0104 0.0622 0.19
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0068 0.0063
Brugia malayi hypothetical protein 0.0076 0.0426 0.0995
Brugia malayi hypothetical protein 0.0042 0.0191 0.0443
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0018 0.0025 0.0018
Schistosoma mansoni rab6-interacting 0.0042 0.0189 0.0182
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0108 0.0203
Brugia malayi sulfakinin receptor protein 0.0076 0.0426 0.0995
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0037 0.003
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0033 0.0027
Echinococcus granulosus serotonin transporter 0.0247 0.1612 0.1606
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0024 0.0068 0.0213
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0104 0.0622 0.1763
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0104 0.0622 0.2386
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0327 0.063
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0104 0.0622 0.2386
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0076 0.0426 0.042
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0048 0.0041
Onchocerca volvulus 0.0076 0.0422 0.123
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.067 0.1751
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0034 0.0134 0.0416
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0393 0.2618 1
Mycobacterium ulcerans oxidoreductase 0.0024 0.0068 0.0106
Echinococcus granulosus voltage gated potassium channel 0.003 0.0109 0.0102
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0393 0.2618 1
Schistosoma mansoni neuropeptide receptor 0.0076 0.0426 0.042
Schistosoma mansoni amine GPCR 0.0415 0.2771 0.2766
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.038 0.2527 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0423 0.0817
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0002
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.0184 0.0177
Loa Loa (eye worm) hypothetical protein 0.0026 0.0083 0.0202
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0191 0.0557
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0012 0.0024
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0084
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0109
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0191 0.0184
Toxoplasma gondii FATC domain-containing protein 0.0018 0.0025 0.0039
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0335 0.0329
Brugia malayi CHD4 protein 0.0015 0.0007 0.0012
Brugia malayi Tachykinin-like peptides receptor 99D 0.0076 0.0426 0.0995
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0059 0.0052
Loa Loa (eye worm) hypothetical protein 0.0379 0.252 0.6638
Echinococcus granulosus Ankyrin 0.0016 0.001 0.0003
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0095 0.0558 0.0573
Schistosoma mansoni neuropeptide f receptor 76f 0.0076 0.0426 0.042
Mycobacterium leprae Conserved hypothetical protein 0.0034 0.0134 0.0318
Onchocerca volvulus 0.0104 0.0622 0.1822
Echinococcus multilocularis microtubule associated protein 2 0.146 1 1
Echinococcus multilocularis g protein coupled receptor 0.0076 0.0426 0.042
Onchocerca volvulus 0.0076 0.0426 0.124
Schistosoma mansoni sodium-dependent amino acid transporter 0.0042 0.0191 0.0184
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0104 0.0622 0.19
Leishmania major ferredoxin, 2fe-2s-like protein 0.0024 0.0068 0.0063
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0084 0.0479 0.1664
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1969 0.3829
Echinococcus multilocularis mitogen activated protein kinase 14 0.0421 0.281 0.2805
Echinococcus multilocularis hyperpolarization activated cyclic 0.0023 0.0059 0.0052
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0034 0.0134 0.0302
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0048 0.0041
Brugia malayi hypothetical protein 0.0053 0.0269 0.0627
Schistosoma mansoni hypothetical protein 0.0016 0.0009 0.0002
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0042 0.0188 0.048
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0034 0.0134 0.0416
Loa Loa (eye worm) hypothetical protein 0.0042 0.0191 0.0486
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0092 0.0536 0.053
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0042 0.0188 0.0182
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0032 0.0121 0.0114
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0042 0.0188 0.055
Brugia malayi hypothetical protein 0.0076 0.0426 0.0995
Brugia malayi Blistered cuticle protein 3 0.0079 0.0449 0.1049
Trypanosoma cruzi NADH dehydrogenase, putative 0.0104 0.0622 0.0639
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0121 0.0279
Echinococcus granulosus 7tm_1 domain containing protein 0.0076 0.0426 0.042
Loa Loa (eye worm) phosphofructokinase 0.0111 0.067 0.1751
Echinococcus multilocularis mitogen activated protein kinase 14 0.0421 0.281 0.2805
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Toxoplasma gondii exonuclease III APE 0.0019 0.0033 0.0066
Echinococcus granulosus alpha 1A adrenergic receptor 0.0076 0.0426 0.042
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0224 0.1453 0.4254
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0104 0.0622 0.0615
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.018 0.0566
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0104 0.0622 0.2386
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0034 0.0134 0.0302
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0104 0.0622 0.2276
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0025 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.018 0.0343
Mycobacterium ulcerans oxidoreductase 0.0024 0.0068 0.0106
Echinococcus granulosus GPCR family 2 0.0016 0.0012 0.0005
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0024 0.0068 0.0063
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0191 0.0184
Leishmania major hypothetical protein, conserved 0.0104 0.0622 0.0639
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0034 0.0134 0.0416
Schistosoma mansoni adrenodoxin 0.0024 0.0068 0.0062
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0104 0.0622 0.2218
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0145 0.09 0.2598
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0012 0.0005
Echinococcus multilocularis zinc finger protein 0.0022 0.0051 0.0044
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.003 0.0051
Echinococcus multilocularis neuropeptide Y receptor 0.0076 0.0426 0.042
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.1969 0.7771
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0108 0.0299
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0048 0.0041
Onchocerca volvulus 0.0076 0.0426 0.124
Schistosoma mansoni cytochrome P450 0.0034 0.0134 0.0127
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0018 0.0025 0.0017
Onchocerca volvulus 0.0042 0.0191 0.0541
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0042 0.0188 0.0438
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0035 0.0141 0.0134
Schistosoma mansoni neuropeptide F-like receptor 0.0076 0.0426 0.042
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0076 0.0426 0.042
Onchocerca volvulus 0.0021 0.0048 0.0117
Schistosoma mansoni ap endonuclease 0.0019 0.0033 0.0027
Mycobacterium ulcerans oxygenase 0.0024 0.0068 0.0106
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0052 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0034 0.0134 0.0416
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.0622 0.193
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0048 0.0041
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0076 0.0426 0.0995
Brugia malayi larval opioid receptor 0.0076 0.0426 0.0995
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0189 0.0182
Toxoplasma gondii hypothetical protein 0.0042 0.0191 0.0557
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0121 0.0228
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0048 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0048 0.0109
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.067 0.1297
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Echinococcus multilocularis lamin dm0 0.0057 0.0295 0.0288
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0086 0.0492 0.0486
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0037 0.003
Loa Loa (eye worm) hypothetical protein 0.0042 0.0191 0.0486
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0104 0.0622 0.1763
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0253 0.0651
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0104 0.0622 0.0615
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0016 0.001
Plasmodium falciparum cGMP-dependent protein kinase 0.0017 0.0016 0.0014
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0095 0.0558 0.0573
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0076 0.0426 0.042
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0342 0.0335
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1969 0.3829
Loa Loa (eye worm) hypothetical protein 0.0247 0.1612 0.424
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0048 0.0041
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0033 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0389 0.0751
Echinococcus granulosus neuropeptide Y receptor 0.0076 0.0426 0.042
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0154 0.0148
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0072 0.0399 0.1036
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0479 0.1456
Echinococcus multilocularis hyperpolarization activated cyclic 0.0023 0.0059 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0255 0.0489
Echinococcus multilocularis tumor protein p63 0.0715 0.4845 0.4842
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0104 0.0622 0.2218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0423 0.0817
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.0911 0.2631
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0076 0.0426 0.042
Schistosoma mansoni netrin receptor unc5 0.0016 0.0009 0.0002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0009 0.0017
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0357 0.2369 0.7356
Brugia malayi cytochrome P450 0.0034 0.0134 0.031
Echinococcus granulosus dro:myosuppressin receptor 0.0076 0.0426 0.042
Plasmodium vivax SET domain protein, putative 0.0064 0.0342 0.1028
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0068 0.0213
Echinococcus multilocularis lamin 0.0057 0.0295 0.0288
Onchocerca volvulus 0.0042 0.0189 0.0535
Loa Loa (eye worm) hypothetical protein 0.0104 0.0618 0.1615
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.018 0.0178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0255 0.049
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0104 0.0622 0.1204
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0377 0.2507 0.2606
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0048 0.0109
Brugia malayi Death domain containing protein 0.0016 0.0009 0.0017
Echinococcus granulosus tm gpcr rhodopsin 0.0924 0.6288 0.6286
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.0622 0.193
Schistosoma mansoni histamine h1 receptor 0.0076 0.0426 0.042
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0376 0.037
Trichomonas vaginalis glutamate synthase, putative 0.0104 0.0622 0.1204
Brugia malayi Dopamine receptor 0.0076 0.0426 0.0995
Echinococcus multilocularis RUN 0.0042 0.0189 0.0182
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0104 0.0622 0.0615
Toxoplasma gondii hypothetical protein 0.0042 0.0191 0.0557
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Giardia lamblia DINP protein human, muc B family 0.002 0.0037 0.0013
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0052 0.0262 0.0686
Echinococcus multilocularis 0.0034 0.0134 0.0127
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0108 0.0289
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0007 0.0007
Echinococcus multilocularis dna polymerase kappa 0.002 0.0037 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.003 0.0051
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0121 0.0301
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0189 0.0182
Schistosoma mansoni amine GPCR 0.0076 0.0426 0.042
Echinococcus granulosus g protein coupled receptor 0.0076 0.0426 0.042
Onchocerca volvulus 0.0076 0.0426 0.124
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0033 0.0058
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0037 0.0158 0.0156
Loa Loa (eye worm) neuropeptide F receptor 0.0076 0.0426 0.1107
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0104 0.0622 0.0615
Leishmania major hypothetical protein, conserved 0.0053 0.0269 0.0272
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0037 0.0114
Plasmodium falciparum ferrodoxin reductase-like protein 0.0104 0.0622 0.19
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0037 0.003
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0034 0.0134 0.0416
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0059 0.0052
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0076 0.0426 0.0995
Echinococcus granulosus tyrosine protein kinase Blk 0.0035 0.0141 0.0134
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.0622 0.193
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0032 0.0121 0.0117
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0048 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0034 0.0134 0.0416
Brugia malayi MAP kinase sur-1 0.0109 0.0657 0.1535
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.1969 0.7771
Leishmania major protein kinase, putative 0.0017 0.0016 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.0426 0.042
Schistosoma mansoni hypothetical protein 0.0021 0.0046 0.0039
Entamoeba histolytica protein kinase, putative 0.0031 0.0114 0.0358
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0112 0.0277
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0023 0.0059 0.0138
Onchocerca volvulus 0.0076 0.0426 0.124
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.0007
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0048 0.0109
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0167 0.016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0341 0.0658
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0048 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0072
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0023 0.0059 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0121 0.0228
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0121 0.0228
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0191 0.0184
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1969 0.3829
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0104 0.0622 0.193
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0357 0.2369 0.7003
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0048 0.0117
Onchocerca volvulus 0.0042 0.0189 0.0535
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0012 0.0005
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0104 0.0622 0.2386
Loa Loa (eye worm) AGC/PKG protein kinase 0.0017 0.0016 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0389 0.0751
Trypanosoma brucei NADH dehydrogenase 0.0104 0.0622 0.0639
Entamoeba histolytica thioredoxin reductase, putative 0.0104 0.0622 0.2386
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.067 0.2079
Treponema pallidum sodium- and chloride- dependent transporter 0.0247 0.1612 0.6107
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0042 0.0188 0.0655
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0167 0.016
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0104 0.0622 0.0639
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0393 0.2618 0.8128
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0005
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0191 0.0184
Schistosoma mansoni microtubule-associated protein tau 0.146 1 1
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0034 0.0134 0.0416
Schistosoma mansoni neuropeptide receptor 0.0076 0.0426 0.042
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0104 0.0622 0.2218
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0076 0.0426 0.042
Echinococcus granulosus neuropeptides capa receptor 0.0076 0.0426 0.042
Echinococcus multilocularis ferredoxin adrenodoxin 0.0024 0.0068 0.0062
Loa Loa (eye worm) hypothetical protein 0.0053 0.0269 0.0693
Brugia malayi G-protein coupled receptor 0.0076 0.0426 0.0995
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0191 0.0557
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0034 0.0134 0.0302
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0009 0.0002
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0121 0.0117
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0104 0.0622 0.0639
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.1249 0.2427
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0033 0.0066
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0104 0.0622 0.19
Plasmodium vivax amine transporter, putative 0.0042 0.0191 0.0557
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0033 0.0058
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0104 0.0622 0.0615
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0269 0.0801
Trichomonas vaginalis mercuric reductase, putative 0.0393 0.2618 0.5092
Schistosoma mansoni hypothetical protein 0.0085 0.0486 0.048
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0033 0.0026
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0104 0.0622 0.193
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1402 0.9598 1
Brugia malayi neuropeptide F receptor 0.0076 0.0426 0.0995
Echinococcus granulosus biogenic amine 5HT receptor 0.0201 0.1288 0.1282
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0024 0.0068 0.0063
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0109 0.0657 0.0676
Echinococcus granulosus 7TM GPCR rhodopsin 0.0076 0.0426 0.042
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Brugia malayi Bromodomain containing protein 0.0079 0.0443 0.1035
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0048 0.0041
Brugia malayi G protein-coupled receptor 0.0076 0.0426 0.0995
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0104 0.0622 0.1763
Schistosoma mansoni biogenic amine receptor 0.0076 0.0426 0.042
Schistosoma mansoni hypothetical protein 0.0076 0.0426 0.042
Mycobacterium tuberculosis Possible oxygenase 0.0024 0.0068 0.0213
Onchocerca volvulus 0.0102 0.0606 0.1776
Echinococcus granulosus dna polymerase eta 0.002 0.0037 0.003
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0021 0.0014
Entamoeba histolytica disulphide oxidoreductase, putative 0.0104 0.0622 0.2386
Loa Loa (eye worm) cytochrome P450 0.0034 0.0134 0.0336
Schistosoma mansoni hypothetical protein 0.0016 0.0012 0.0005
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0092 0.0536 0.053
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0012 0.0004
Schistosoma mansoni intermediate filament proteins 0.0057 0.0295 0.0288
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0393 0.2618 0.6132
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0344 0.1035
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0033 0.0026
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0247 0.1612 0.1606
Schistosoma mansoni opsin-like receptor 0.0076 0.0426 0.042
Brugia malayi hypothetical protein 0.0076 0.0426 0.0995
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Loa Loa (eye worm) TK protein kinase 0.0035 0.0141 0.0354
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0104 0.0622 0.0639
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0076 0.0426 0.042
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0021 0.0014
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0095 0.0558 0.1304
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0081 0.0462 0.0456
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0048 0.0109
Loa Loa (eye worm) hypothetical protein 0.003 0.0109 0.0269
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0042 0.0188 0.036
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.0426 0.042
Brugia malayi Protein kinase domain containing protein 0.0018 0.0026 0.0057
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0104 0.0622 0.1453
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0048 0.0041
Onchocerca volvulus 0.0076 0.0426 0.124
Schistosoma mansoni sulfide quinone reductase 0.0104 0.0622 0.0615
Loa Loa (eye worm) hypothetical protein 0.0201 0.1288 0.3385
Leishmania major phosphatidylinositol 3-kinase, putative 0.0032 0.0121 0.0117
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0012 0.0005
Brugia malayi hypothetical protein 0.0076 0.0426 0.0995
Brugia malayi Cytochrome P450 family protein 0.0052 0.0262 0.0611
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0076 0.0426 0.042
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.048 0.3221 1
Echinococcus granulosus hypothetical protein 0.0909 0.619 0.6187
Loa Loa (eye worm) glutathione reductase 0.048 0.3221 0.849
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0195 0.1249 0.3688
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0048 0.0041
Giardia lamblia Kinase, CMGC MAPK 0.0109 0.0657 0.2411
Schistosoma mansoni hypothetical protein 0.0076 0.0426 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0423 0.0817
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0342 0.0335
Echinococcus granulosus cGMP dependent protein kinase 0.0017 0.0016 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0025 0.0041
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0421 0.281 0.2922
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0104 0.0622 0.193
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0042 0.0188 0.0188
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0033 0.007
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0034 0.0134 0.0302
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0039 0.0167 0.016
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0342 0.1028
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0034 0.0134 0.0416
Loa Loa (eye worm) hypothetical protein 0.0195 0.1249 0.3282
Echinococcus granulosus neuropeptide receptor 0.0076 0.0426 0.042
Trypanosoma brucei hypothetical protein, conserved 0.0104 0.0622 0.0639
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0108 0.0203
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0076 0.0426 0.042
Onchocerca volvulus 0.0076 0.0426 0.124
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0295 0.0687
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0255 0.0489
Mycobacterium tuberculosis Probable reductase 0.0104 0.0622 0.193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0558 0.108
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0104 0.0622 0.0615
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0076 0.0426 0.0995
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0108 0.0203
Loa Loa (eye worm) hypothetical protein 0.0042 0.0189 0.0481
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0076 0.0426 0.042
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0009 0.0002
Mycobacterium ulcerans dehydrogenase 0.0104 0.0622 0.1763
Loa Loa (eye worm) neuropeptide F receptor 0.0076 0.0426 0.1107
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.0426 0.042
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0048 0.0109
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.018 0.0178
Loa Loa (eye worm) hypothetical protein 0.0042 0.0189 0.0481
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0023 0.0059 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0034 0.0134 0.0416
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0086 0.0492 0.1282
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.0039 0.0083
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0023 0.0059 0.0052
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1181 0.2292
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0104 0.0622 0.0639
Echinococcus granulosus tyrosine protein kinase Src64B 0.0039 0.0167 0.016
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0059 0.0052
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0393 0.2618 0.8121
Mycobacterium ulcerans epimerase 0.0022 0.0052 0.0057
Brugia malayi Melatonin receptor type 1A 0.0076 0.0426 0.0995
Trypanosoma cruzi adrenodoxin precursor, putative 0.0024 0.0068 0.0063
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0109 0.0657 0.0676
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0034 0.0134 0.0302
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1181 0.2292
Schistosoma mansoni hypothetical protein 0.0102 0.0606 0.06
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.067 0.1297
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1402 0.9598 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0076 0.0426 0.042
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Onchocerca volvulus 0.0502 0.3373 1
Schistosoma mansoni hypothetical protein 0.0104 0.0622 0.0615
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0072 0.0065
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0167 0.016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1032 0.7035 0.7327
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0039 0.0167 0.016
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0247 0.1612 0.3774
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0076 0.0422 0.0416
Toxoplasma gondii ferodoxin FD 0.0024 0.0068 0.0176
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.067 0.0663
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.118 0.8062 0.8399
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0048 0.0109
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0048 0.0041
Brugia malayi SRC-1 0.0039 0.0167 0.0387
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0042 0.0188 0.036
Echinococcus multilocularis serine protein kinase ATM 0.0018 0.0025 0.0018
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.003 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0121 0.0228
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0037 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0109
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0048 0.0041
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0191 0.0557
Schistosoma mansoni amine GPCR 0.0076 0.0426 0.042
Giardia lamblia [2Fe-2S] ferredoxin 0.0024 0.0068 0.0136
Brugia malayi Cytochrome P450 family protein 0.0034 0.0134 0.031
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0025 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0389 0.0751
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0393 0.2618 0.7748
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0024 0.0068 0.0062
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0048 0.0041
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0104 0.0622 0.0639
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0048 0.0109
Trichomonas vaginalis glutathione reductase, putative 0.0393 0.2618 0.5092
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0037 0.001
Schistosoma mansoni opsin-like receptor 0.0076 0.0426 0.042
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0034 0.0134 0.0302
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1032 0.7035 0.7327
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0104 0.0622 0.19
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0048 0.0109
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0479 0.1456
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0104 0.0622 0.1204
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0191 0.0486
Echinococcus granulosus cGMP dependent protein kinase 1 0.0017 0.0016 0.001
Loa Loa (eye worm) hypothetical protein 0.0201 0.1288 0.3385
Brugia malayi glutamate synthase 0.0104 0.0622 0.1453
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1402 0.9598 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0191 0.0443
Schistosoma mansoni sodium/chloride dependent transporter 0.0045 0.0208 0.0201
Echinococcus granulosus tyrosine kinase 0.0035 0.0141 0.0134
Schistosoma mansoni bromodomain containing protein 0.0067 0.036 0.0354
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0023 0.0059 0.0052
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0039 0.0167 0.016
Onchocerca volvulus 0.0076 0.0426 0.124
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0012 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.1852 0.36
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0039 0.0068
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0092 0.0536 0.053
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0108 0.0155
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0048 0.0109
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0023 0.0059 0.0138
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0289 0.1897 0.4441
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Onchocerca volvulus Dual oxidase homolog 0.0079 0.0449 0.1309
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0189 0.0182
Brugia malayi M-phase phosphoprotein, mpp8 0.0104 0.0617 0.1442
Leishmania major hypothetical protein, conserved 0.0104 0.0622 0.0639
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0191 0.0184
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0059 0.0052
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Treponema pallidum hypothetical protein 0.0101 0.0601 0.2197
Echinococcus multilocularis tyrosine protein kinase Blk 0.0035 0.0141 0.0134
Schistosoma mansoni biogenic amine receptor 0.0076 0.0426 0.042
Schistosoma mansoni growth hormone secretagogue receptor 0.0076 0.0426 0.042
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0095 0.0558 0.0551
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Schistosoma mansoni myosin xvIII 0.0076 0.0426 0.042
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0104 0.0622 0.1204
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0048 0.0117
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0034 0.0134 0.0302
Schistosoma mansoni neuropeptide F-like receptor 0.0076 0.0426 0.042
Trichomonas vaginalis Ferredoxin 1 0.0024 0.0068 0.0126
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0076 0.0424 0.0433
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0109 0.0657 0.0676
Loa Loa (eye worm) hypothetical protein 0.0379 0.252 0.6638
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0037 0.0064
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.0622 0.2218
Schistosoma mansoni hypothetical protein 0.0447 0.2991 0.2986
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0034 0.0134 0.0302
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0253 0.0589
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0039 0.0167 0.016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.0426 0.042
Echinococcus granulosus neuropeptide receptor A26 0.0579 0.3902 0.3898
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0191 0.0486
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0012 0.0005
Trichomonas vaginalis Ferredoxin 4 0.0024 0.0068 0.0126
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0335 0.0329
Leishmania major NADH dehydrogenase, putative 0.0104 0.0622 0.0639
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0145 0.09 0.2598
Loa Loa (eye worm) hypothetical protein 0.05 0.3357 0.885
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.1852 0.36
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.067 0.1297
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0034 0.0134 0.0131
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0282 0.1852 0.4873
Schistosoma mansoni biogenic amine (5HT) receptor 0.0487 0.327 0.3266
Echinococcus granulosus tm gpcr rhodopsin 0.0076 0.0426 0.042
Echinococcus granulosus cGMP dependent protein kinase 1 0.0017 0.0016 0.001
Loa Loa (eye worm) hypothetical protein 0.0051 0.0253 0.0651
Schistosoma mansoni sodium/chloride dependent transporter 0.0247 0.1612 0.1606
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0072 0.0399 0.0392
Echinococcus multilocularis mitogen activated protein kinase 3 0.0109 0.0657 0.065
Mycobacterium ulcerans glutamate synthase subunit beta 0.0104 0.0622 0.1763
Echinococcus granulosus g protein coupled receptor 0.0076 0.0426 0.042
Loa Loa (eye worm) CYP4Cod1 0.0052 0.0262 0.0675
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0012 0.0005
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0393 0.2618 0.7748
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.118 0.8062 0.8399
Schistosoma mansoni lipoxygenase 0.025 0.1626 0.1621
Brugia malayi AKH receptor 0.0076 0.0426 0.0995
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0085 0.0486 0.048
Brugia malayi glutathione reductase 0.048 0.3221 0.7545
Echinococcus granulosus death domain containing protein 0.0016 0.0009 0.0002
Onchocerca volvulus 0.0076 0.0426 0.124
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0393 0.2618 0.8121
Loa Loa (eye worm) hypothetical protein 0.05 0.3357 0.885
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0034 0.0134 0.0302
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0025 0.0054
Giardia lamblia Thioredoxin reductase 0.0104 0.0622 0.2276
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0399 0.0407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0025 0.0041
Echinococcus granulosus neuropeptides capa receptor 0.0076 0.0426 0.042
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0256 0.1668 0.518
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.1852 0.36
Echinococcus multilocularis orexin receptor type 2 0.0076 0.0426 0.042
Brugia malayi Doublecortin family protein 0.0042 0.0189 0.0438
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0048 0.0041
Echinococcus granulosus biogenic amine 5HT receptor 0.0487 0.327 0.3266
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0024 0.0068 0.0157
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0024 0.0068 0.0136
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0037 0.003
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0189 0.0182
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0095 0.0558 0.0551
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0034 0.0134 0.0416
Loa Loa (eye worm) hypothetical protein 0.0084 0.0479 0.1248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0558 0.108
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0042 0.0188 0.048
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0109
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0042 0.0188 0.0182
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0256 0.1668 0.4901
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0072 0.0065
Mycobacterium tuberculosis Probable oxidoreductase 0.0393 0.2618 0.8128
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.0426 0.042
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0191 0.0184
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.0426 0.042
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0095 0.0558 0.2131
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0012 0.0014
Brugia malayi Egg laying defective protein 4 0.0017 0.0016 0.0034
Plasmodium falciparum glutathione reductase 0.048 0.3221 1
Mycobacterium ulcerans ferredoxin reductase 0.0104 0.0622 0.1763
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.018 0.0178
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0076 0.0426 0.042
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0191 0.0184
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0379 0.252 0.2515
Onchocerca volvulus 0.0076 0.0426 0.124
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0104 0.0622 0.1763
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0024 0.0068 0.0163
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0104 0.0622 0.19
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0021 0.0014
Brugia malayi CXXC zinc finger family protein 0.0031 0.0117 0.0271
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0108 0.0155
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0104 0.0622 0.0639
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0048 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1969 0.3829
Echinococcus multilocularis Ankyrin 0.0016 0.001 0.0003
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0034 0.0134 0.0302
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.018 0.0173
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0048 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0034 0.0134 0.0416
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0104 0.0622 0.19
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0037 0.003
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0189 0.0551
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0269 0.0801
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0393 0.2618 0.8128
Mycobacterium ulcerans hypothetical protein 0.0022 0.0052 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0048 0.0109
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0009 0.0002
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.018 0.0173
Schistosoma mansoni amine GPCR 0.0076 0.0426 0.042
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0033 0.0026
Loa Loa (eye worm) G-protein coupled receptor 0.0076 0.0426 0.1107
Schistosoma mansoni lamin 0.0057 0.0295 0.0288
Brugia malayi ORL1-like opioid receptor 0.0076 0.0426 0.0995
Echinococcus granulosus Adrenodoxin mitochondrial 0.0024 0.0068 0.0062
Trypanosoma cruzi adrenodoxin precursor, putative 0.0024 0.0068 0.0063
Onchocerca volvulus 0.0076 0.0426 0.124
Leishmania major ferric reductase, putative 0.0037 0.0158 0.0156
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0462 0.0456
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0085 0.0486 0.048
Plasmodium falciparum transporter, putative 0.0042 0.0191 0.0557
Echinococcus granulosus dnaJ subfamily B 0.0447 0.2991 0.2986
Leishmania major cytochrome p450-like protein 0.0034 0.0134 0.0131
Echinococcus multilocularis tyrosine protein kinase HCK 0.0031 0.0114 0.0107
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0037 0.003
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0104 0.0622 0.1204
Schistosoma mansoni neuropeptide receptor 0.0076 0.0426 0.042
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0104 0.0622 0.0639
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0048 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0462 0.0456
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.0426 0.042
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0393 0.2618 0.7748
Trypanosoma brucei trypanothione reductase 0.048 0.3221 0.335
Brugia malayi hypothetical protein 0.0076 0.0426 0.0995
Onchocerca volvulus 0.0076 0.0426 0.124
Echinococcus multilocularis neuropeptide Y receptor 0.0076 0.0426 0.042
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0104 0.0622 0.0639
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.018 0.0417
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0042 0.0191 0.0184
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0076 0.0426 0.042
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0057
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0191 0.0184
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.1852 0.36
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0034 0.0134 0.0416
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0034 0.0134 0.0416
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0191 0.0184
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0389 0.0751
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0076 0.0426 0.042
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.001 0.0003
Treponema pallidum NADH oxidase 0.0393 0.2618 1
Echinococcus granulosus lamin 0.0057 0.0295 0.0288
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0253 0.0589
Loa Loa (eye worm) hypothetical protein 0.0042 0.0191 0.0486
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0048 0.0041
Echinococcus granulosus orexin receptor type 2 0.0076 0.0426 0.042
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.018 0.0173
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0108 0.0299
Plasmodium vivax thioredoxin reductase, putative 0.048 0.3221 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0009 0.0005
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0033 0.0027
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0104 0.0622 0.193
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0037 0.003
Echinococcus multilocularis dro:myosuppressin receptor 0.0076 0.0426 0.042
Echinococcus granulosus G protein coupled receptor 139 0.0076 0.0426 0.042
Echinococcus granulosus hyperpolarization activated cyclic 0.0023 0.0059 0.0052
Echinococcus multilocularis somatostatin receptor 0.0076 0.0426 0.042
Echinococcus multilocularis nuclear factor of activated T cells 5 0.008 0.0457 0.045
Onchocerca volvulus Neuropeptide F receptor homolog 0.0076 0.0426 0.124
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0018 0.0025 0.0018
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0269 0.0801
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0108 0.0203
Echinococcus multilocularis neuropeptides capa receptor 0.0076 0.0426 0.042
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.067 0.1297
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1969 0.3829
Loa Loa (eye worm) hypothetical protein 0.0057 0.0295 0.0761
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.0426 0.042
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0037 0.003
Brugia malayi Thioredoxin reductase 0.048 0.3221 0.7545
Mycobacterium ulcerans hypothetical protein 0.0123 0.0751 0.2153
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0016 0.0014 0.0007
Echinococcus granulosus somatostatin receptor 0.0076 0.0426 0.042
Schistosoma mansoni sodium/chloride dependent transporter 0.0042 0.0191 0.0184
Echinococcus multilocularis neuropeptide receptor A26 0.0579 0.3902 0.3898
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0034 0.0134 0.0302
Brugia malayi hypothetical protein 0.05 0.3361 0.7873
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0072 0.0399 0.1496
Loa Loa (eye worm) hypothetical protein 0.0056 0.0288 0.0742
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.067 0.2578
Brugia malayi protein-tyrosine kinase 0.0035 0.0141 0.0326
Echinococcus multilocularis conserved hypothetical protein 0.0833 0.5664 0.5661
Schistosoma mansoni zinc finger protein 0.0016 0.0008 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0389 0.0751
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0393 0.2618 0.2613
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.018 0.0173
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Plasmodium falciparum amino acid transporter, putative 0.0042 0.0191 0.0557
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0037 0.003
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0017 0.0016 0.0014
Trichomonas vaginalis aldehyde oxidase, putative 0.0757 0.5138 1
Loa Loa (eye worm) hypothetical protein 0.0193 0.1232 0.3238
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.0911 0.2828
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0108 0.0299
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0042 0.0191 0.0184
Schistosoma mansoni survival motor neuron protein 0.0102 0.0606 0.06
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0095 0.0558 0.0573
Mycobacterium ulcerans hypothetical protein 0.0104 0.0622 0.1763
Onchocerca volvulus 0.0042 0.0191 0.0541
Schistosoma mansoni voltage-gated potassium channel 0.0093 0.0542 0.0535
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0393 0.2618 0.2721
Leishmania major cytochrome p450-like protein 0.0052 0.0262 0.0265
Toxoplasma gondii endonuclease IV APN 0.0084 0.0479 0.1456
Brugia malayi hypothetical protein 0.0076 0.0426 0.0995
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0077 0.0142
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0138
Plasmodium falciparum thioredoxin reductase 0.048 0.3221 1
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0104 0.0622 0.2276
Echinococcus multilocularis musashi 0.0057 0.0295 0.0288
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0033 0.0074
Mycobacterium ulcerans NADH dehydrogenase 0.0104 0.0622 0.1763
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0104 0.0622 0.0615
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0023 0.0059 0.0052
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0052 0.0119
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0042 0.0191 0.0443
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0017 0.0016 0.001
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0012 0.0004
Toxoplasma gondii selenide, water dikinase 0.0104 0.0622 0.19
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0032 0.0121 0.0114
Schistosoma mansoni alpha-1 adrenergic receptor 0.0076 0.0426 0.042
Brugia malayi nuclear receptor NHR-88 0.0021 0.0048 0.0109
Echinococcus multilocularis mitogen activated protein kinase 11 0.0421 0.281 0.2805
Echinococcus multilocularis tyrosine protein kinase Srms 0.0035 0.0141 0.0134
Toxoplasma gondii target of rapamycin (TOR), putative 0.0071 0.0389 0.1176
Echinococcus granulosus arachidonate 5 lipoxygenase 0.025 0.1626 0.1621
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0037 0.003
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0108 0.0334
Treponema pallidum fructose-bisphosphate aldolase 0.0299 0.1969 0.749
Schistosoma mansoni coup transcription factor 0.0021 0.0048 0.0041
Schistosoma mansoni adenoreceptor 0.0076 0.0426 0.042
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.018 0.0173
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0108 0.0289
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.0426 0.042
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0037 0.0079
Schistosoma mansoni glutamate synthase 0.0104 0.0622 0.0615
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0104 0.0622 0.0615
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0393 0.2618 0.2721
Schistosoma mansoni lamin 0.0057 0.0295 0.0288
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0024 0.0068 0.0178
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0072 0.0399 0.0392
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0012 0.0005
Plasmodium falciparum ferredoxin, putative 0.0024 0.0068 0.0176
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0167 0.016
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0191 0.0443
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0109
Leishmania major ferredoxin 2fe-2s-like protein 0.0024 0.0068 0.0063
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0262 0.0675
Brugia malayi putative neuropeptide receptor NPR1 0.0076 0.0426 0.0995
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0133 0.0127
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0109
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0009 0.0002
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0104 0.0622 0.1624
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0048 0.0041
Loa Loa (eye worm) hypothetical protein 0.0085 0.0486 0.1267
Echinococcus multilocularis g-protein coupled receptor 0.0076 0.0426 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0025 0.0041
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.018 0.0343
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.0426 0.042
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0104 0.0622 0.1204
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0052 0.013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0924 0.6288 0.6286
Onchocerca volvulus 0.0031 0.0117 0.0322
Onchocerca volvulus 0.0104 0.0617 0.1808
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0021 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0293 0.0564
Loa Loa (eye worm) programmed cell death 8 0.0104 0.0622 0.1624
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0421 0.281 0.7405
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.0426 0.042
Schistosoma mansoni glutamate synthase 0.0104 0.0622 0.0615
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0189 0.0182
Brugia malayi Bromodomain containing protein 0.0039 0.0171 0.0397
Loa Loa (eye worm) cytochrome P450 family protein 0.0095 0.0557 0.1455
Echinococcus granulosus zinc finger protein 0.0022 0.0051 0.0044
Loa Loa (eye worm) hypothetical protein 0.0026 0.0083 0.0202
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0399 0.0407
Trypanosoma cruzi trypanothione reductase, putative 0.048 0.3221 0.335
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0462 0.0892
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.003 0.0051
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0076 0.0426 0.1107
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.0622 0.193
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0421 0.281 0.2922
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0048 0.0109
Loa Loa (eye worm) hypothetical protein 0.0042 0.0191 0.0486
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0034 0.0134 0.0416
Trypanosoma brucei C-8 sterol isomerase, putative 0.0377 0.2507 0.2606
Loa Loa (eye worm) SRC-1 0.0039 0.0167 0.0422
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0076 0.0426 0.042
Echinococcus multilocularis GPCR, family 2 0.0016 0.0012 0.0005
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0076 0.0426 0.042
Brugia malayi steroid hormone receptor 0.0021 0.0048 0.0109
Brugia malayi P38 map kinase family protein 2 0.0421 0.281 0.6583
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0657 0.1272
Loa Loa (eye worm) hypothetical protein 0.0105 0.0624 0.163
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0077 0.0432 0.0834
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0757 0.5138 1
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0034 0.0134 0.0302
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.018 0.0173
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0039 0.0167 0.016
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0012 0.0004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.018 0.062
Onchocerca volvulus 0.0024 0.0068 0.0178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0423 0.0817
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0076 0.0426 0.042
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.003 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0016 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0255 0.0489
Echinococcus granulosus g protein coupled receptor 0.0076 0.0426 0.042
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0034 0.0134 0.0302
Mycobacterium ulcerans electron transfer protein FdxB 0.0024 0.0068 0.0106
Schistosoma mansoni opsin-like receptor 0.0076 0.0426 0.042
Loa Loa (eye worm) hypothetical protein 0.0076 0.0426 0.1107
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0108 0.0203
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0023 0.0059 0.0052
Echinococcus multilocularis neuropeptide receptor 0.0076 0.0426 0.042
Plasmodium falciparum glutathione reductase 0.0393 0.2618 0.8121
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0048 0.0109
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0502 0.3369 1
Schistosoma mansoni hypothetical protein 0.0076 0.0426 0.042
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0487 0.327 0.3266
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.0426 0.042
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0657 0.1272
Echinococcus granulosus cpg binding protein 0.0035 0.0143 0.0136
Brugia malayi hypothetical protein 0.0076 0.0426 0.0995
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.067 0.0663
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0076 0.0426 0.042
Onchocerca volvulus 0.0076 0.0426 0.124
Schistosoma mansoni hypothetical protein 0.0035 0.0141 0.0135
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0033 0.0103
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0104 0.0622 0.2386

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 270 nM Displacement of [3H]mesulergine from human recombinant 5HT2B receptor expressed in CHO cells ChEMBL. 18282705
Ki (binding) = 270 nM Displacement of [3H]mesulergine from human recombinant 5HT2B receptor expressed in CHO cells ChEMBL. 18282705
Ki (binding) = 1200 nM Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in mouse NIH3T3 cells ChEMBL. 18282705
Ki (binding) = 1200 nM Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in mouse NIH3T3 cells ChEMBL. 18282705
Ki (binding) = 5000 nM Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO cells ChEMBL. 18282705
Ki (binding) = 5000 nM Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO cells ChEMBL. 18282705

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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