Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | mitochondrial ATP synthase delta chain | 0.0135 | 0.0285 | 0.0615 |
Mycobacterium tuberculosis | Probable ATP synthase a chain AtpB (protein 6) | 0.0382 | 0.105 | 0.0868 |
Brugia malayi | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0394 | 0.1091 | 0.2349 |
Echinococcus multilocularis | geminin | 0.0202 | 0.0492 | 0.1369 |
Echinococcus granulosus | synaptic glycoprotein sc2 | 0.0412 | 0.1144 | 0.3186 |
Loa Loa (eye worm) | hypothetical protein | 0.0412 | 0.1144 | 0.2465 |
Plasmodium falciparum | ATP synthase subunit beta, mitochondrial | 0.0074 | 0.0095 | 0.0833 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0216 | 0.0535 | 0.1153 |
Mycobacterium ulcerans | F0F1 ATP synthase subunit B | 0.3237 | 0.9921 | 1 |
Loa Loa (eye worm) | TK protein kinase | 0.0217 | 0.0539 | 0.1161 |
Brugia malayi | ATP synthase lipid-binding protein, mitochondrial precursor | 0.0114 | 0.0219 | 0.0472 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0312 | 0.0834 | 0.1796 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0047 | 0.0012 | 0.0026 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0204 | 0.0498 | 0.1386 |
Schistosoma mansoni | ATP synthase gamma subunit | 0.0108 | 0.02 | 0.0557 |
Schistosoma mansoni | tyrosine kinase | 0.0237 | 0.06 | 0.1671 |
Leishmania major | ATP synthase F1 subunit gamma protein, putative | 0.0108 | 0.02 | 0.0431 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.026 | 0.0674 | 0.1452 |
Chlamydia trachomatis | type III secretion system ATPase | 0.0074 | 0.0095 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0237 | 0.06 | 0.1671 |
Echinococcus multilocularis | suppressor of cytokine signaling 6 | 0.0047 | 0.0012 | 0.0033 |
Trypanosoma brucei | ATP synthase F1, alpha subunit | 0.0135 | 0.0285 | 0.0613 |
Leishmania major | ATPase subunit 9, putative | 0.0114 | 0.0219 | 0.0472 |
Plasmodium falciparum | ATP synthase subunit delta, mitochondrial, putative | 0.0135 | 0.0285 | 0.2494 |
Schistosoma mansoni | ATP synthase lipid-binding protein-like protein | 0.0114 | 0.0219 | 0.061 |
Trypanosoma cruzi | ATPase subunit 9, putative | 0.0114 | 0.0219 | 0.0472 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.006 | 0.0053 | 0.0147 |
Echinococcus granulosus | SH2 motif | 0.0047 | 0.0012 | 0.0033 |
Loa Loa (eye worm) | ATP synthase subunit delta | 0.0135 | 0.0285 | 0.0615 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0237 | 0.06 | 0.1671 |
Trypanosoma brucei | ATP synthase F1 subunit gamma protein, putative | 0.0108 | 0.02 | 0.0431 |
Mycobacterium ulcerans | F0F1 ATP synthase subunit gamma | 0.0108 | 0.02 | 0.0106 |
Brugia malayi | SH2 domain containing protein | 0.006 | 0.0053 | 0.0114 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0047 | 0.0012 | 0.0033 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0237 | 0.06 | 0.1671 |
Echinococcus granulosus | glycogen synthase kinase 3 beta | 0.026 | 0.0674 | 0.1877 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.006 | 0.0053 | 0.0114 |
Echinococcus granulosus | mitogen activated protein kinase 14 | 0.0678 | 0.1972 | 0.549 |
Giardia lamblia | Synaptic glycoprotein SC2 | 0.0412 | 0.1144 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Brugia malayi | Protein kinase domain containing protein | 0.006 | 0.0053 | 0.0114 |
Echinococcus granulosus | protein kinase shaggy | 0.026 | 0.0674 | 0.1877 |
Entamoeba histolytica | protein kinase, putative | 0.0052 | 0.0027 | 0.0059 |
Schistosoma mansoni | ATP synthase lipid-binding protein-like protein | 0.0114 | 0.0219 | 0.061 |
Brugia malayi | ATP synthase beta chain, mitochondrial precursor, putative | 0.0074 | 0.0095 | 0.0205 |
Trypanosoma brucei | Mitochondrial ATP synthase subunit c-3 | 0.0114 | 0.0219 | 0.0472 |
Leishmania major | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 0.026 | 0.0674 | 0.1452 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0678 | 0.1972 | 0.549 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.008 | 0.0114 | 0.0246 |
Echinococcus multilocularis | 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal | 0.0412 | 0.1144 | 0.3186 |
Echinococcus granulosus | suppressor of cytokine signaling 6 | 0.0047 | 0.0012 | 0.0033 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0047 | 0.0012 | 0.0026 |
Entamoeba histolytica | trans-2,3-enoyl-CoA reductase, putative | 0.0412 | 0.1144 | 0.2465 |
Entamoeba histolytica | hypothetical protein | 0.0412 | 0.1144 | 0.2465 |
Loa Loa (eye worm) | cytokine inducible SH2-containing protein 5 | 0.0047 | 0.0012 | 0.0026 |
Leishmania major | ATPase subunit 9, putative | 0.0114 | 0.0219 | 0.0472 |
Entamoeba histolytica | protein kinase, putative | 0.026 | 0.0674 | 0.1452 |
Brugia malayi | protein-tyrosine kinase | 0.0217 | 0.0539 | 0.1161 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0205 | 0.0501 | 0.1079 |
Loa Loa (eye worm) | SRC-1 | 0.0237 | 0.06 | 0.1293 |
Echinococcus granulosus | SH2 motif | 0.0047 | 0.0012 | 0.0033 |
Onchocerca volvulus | 0.006 | 0.0053 | 0.0363 | |
Echinococcus granulosus | ATP synthase subunit beta mitochondrial | 0.0074 | 0.0095 | 0.0265 |
Trypanosoma brucei | Mitochondrial ATP synthase subunit c-2 | 0.0114 | 0.0219 | 0.0472 |
Brugia malayi | cytokine inducible SH2-containing protein 5 | 0.0047 | 0.0012 | 0.0026 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.1538 | 0.4643 | 1 |
Echinococcus granulosus | mitochondrial ATP synthase subunit 9 | 0.0114 | 0.0219 | 0.061 |
Schistosoma mansoni | hypothetical protein | 0.0202 | 0.0492 | 0.1369 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.008 | 0.0114 | 0.0318 |
Wolbachia endosymbiont of Brugia malayi | ATP synthase F0F1 subunit B | 0.0656 | 0.1904 | 1 |
Schistosoma mansoni | ATP synthase gamma subunit | 0.0108 | 0.02 | 0.0557 |
Plasmodium falciparum | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0412 | 0.1144 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0067 | 0.0073 | 0.0203 |
Mycobacterium ulcerans | F0F1 ATP synthase subunit epsilon | 0.0135 | 0.0285 | 0.0193 |
Loa Loa (eye worm) | ATP synthase subunit beta | 0.0049 | 0.0018 | 0.004 |
Loa Loa (eye worm) | CMGC/MAPK/P38 protein kinase | 0.0678 | 0.1972 | 0.4247 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0059 | 0.005 | 0.0107 |
Echinococcus granulosus | geminin | 0.0202 | 0.0492 | 0.1369 |
Schistosoma mansoni | SH2A | 0.0047 | 0.0012 | 0.0033 |
Trypanosoma cruzi | ATP synthase F1 subunit gamma protein, putative | 0.0108 | 0.02 | 0.0431 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0047 | 0.0012 | 0.0026 |
Onchocerca volvulus | 0.006 | 0.0053 | 0.0363 | |
Mycobacterium ulcerans | F0F1 ATP synthase subunit C | 0.0114 | 0.0219 | 0.0126 |
Mycobacterium leprae | PROBABLE ATP SYNTHASE EPSILON CHAIN ATPC | 0.0135 | 0.0285 | 0.0088 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0047 | 0.0012 | 0.0033 |
Echinococcus multilocularis | SH2 domain containing adapter protein F | 0.0047 | 0.0012 | 0.0033 |
Echinococcus granulosus | hypothetical protein | 0.0047 | 0.0012 | 0.0033 |
Brugia malayi | SRC-1 | 0.0237 | 0.06 | 0.1293 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0412 | 0.1144 | 0.2465 |
Onchocerca volvulus | 0.026 | 0.0674 | 0.5848 | |
Brugia malayi | SH2 domain containing protein | 0.0047 | 0.0012 | 0.0026 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.008 | 0.0114 | 0.0318 |
Trypanosoma brucei | ATP synthase F1, alpha subunit | 0.0135 | 0.0285 | 0.0613 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0205 | 0.0501 | 0.1079 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0047 | 0.0012 | 0.0033 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0678 | 0.1972 | 0.549 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0067 | 0.0073 | 0.0203 |
Brugia malayi | Protein kinase domain containing protein | 0.006 | 0.0053 | 0.0114 |
Echinococcus multilocularis | SH2 motif | 0.0047 | 0.0012 | 0.0033 |
Schistosoma mansoni | ATP synthase gamma subunit | 0.0108 | 0.02 | 0.0557 |
Brugia malayi | Synaptic glycoprotein SC2 | 0.0412 | 0.1144 | 0.2465 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0241 | 0.0616 | 0.1713 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.006 | 0.0053 | 0.0114 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0237 | 0.06 | 0.1671 |
Loa Loa (eye worm) | hypothetical protein | 0.0394 | 0.1091 | 0.2349 |
Loa Loa (eye worm) | TK protein kinase | 0.017 | 0.0393 | 0.0845 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0205 | 0.0501 | 0.1079 |
Brugia malayi | Variant SH3 domain containing protein | 0.0067 | 0.0073 | 0.0157 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.006 | 0.0053 | 0.0114 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0678 | 0.1972 | 0.549 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0047 | 0.0012 | 0.0033 |
Echinococcus granulosus | SH2 domain containing adapter protein F | 0.0047 | 0.0012 | 0.0033 |
Loa Loa (eye worm) | RhoGAP domain-containing protein | 0.0047 | 0.0012 | 0.0026 |
Wolbachia endosymbiont of Brugia malayi | ATP synthase F0F1 subunit C | 0.0114 | 0.0219 | 0.0684 |
Schistosoma mansoni | tyrosine kinase | 0.0237 | 0.06 | 0.1671 |
Onchocerca volvulus | 0.006 | 0.0053 | 0.0363 | |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0237 | 0.06 | 0.1671 |
Schistosoma mansoni | nck2/grb4 | 0.0067 | 0.0073 | 0.0203 |
Mycobacterium leprae | PROBABLE ATP SYNTHASE C CHAIN ATPE (LIPID-BINDING PROTEIN) (DICYCLOHEXYLCARBODIIMIDE-BINDING PROTEIN) | 0.0114 | 0.0219 | 0.002 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0059 | 0.005 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.02 | 0.0431 |
Trypanosoma cruzi | ATPase subunit 9, putative | 0.0114 | 0.0219 | 0.0472 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0012 | 0.0033 |
Onchocerca volvulus | ATP synthase subunit delta, mitochondrial homolog | 0.0135 | 0.0285 | 0.2416 |
Echinococcus granulosus | signal transduction protein lnk realted | 0.0047 | 0.0012 | 0.0033 |
Plasmodium vivax | ATP synthase subunit gamma, mitochondrial, putative | 0.0108 | 0.02 | 0.1747 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Schistosoma mansoni | suppressor of cytokine signaling | 0.0047 | 0.0012 | 0.0033 |
Echinococcus multilocularis | mitochondrial ATP synthase subunit 9 | 0.0114 | 0.0219 | 0.061 |
Leishmania major | ATPase subunit 9, putative | 0.0114 | 0.0219 | 0.0472 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0237 | 0.06 | 0.1671 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0217 | 0.0539 | 0.15 |
Echinococcus multilocularis | tyrosine kinase | 0.006 | 0.0053 | 0.0147 |
Echinococcus granulosus | SHC transforming protein 3 | 0.0047 | 0.0012 | 0.0033 |
Brugia malayi | Variant SH3 domain containing protein | 0.0067 | 0.0073 | 0.0157 |
Echinococcus multilocularis | glycogen synthase kinase 3 beta | 0.026 | 0.0674 | 0.1877 |
Schistosoma mansoni | tyrosine-protein kinase zap-70 | 0.0047 | 0.0012 | 0.0033 |
Onchocerca volvulus | ATP synthase subunit gamma, mitochondrial homolog | 0.0108 | 0.02 | 0.1661 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative | 0.1538 | 0.4643 | 1 |
Entamoeba histolytica | steroid 5-alpha reductase, putative | 0.1538 | 0.4643 | 1 |
Mycobacterium tuberculosis | Probable ATP synthase epsilon chain AtpC | 0.0135 | 0.0285 | 0.0087 |
Mycobacterium tuberculosis | Probable ATP synthase alpha chain AtpA | 0.016 | 0.0362 | 0.0165 |
Schistosoma mansoni | vav2 | 0.0047 | 0.0012 | 0.0033 |
Echinococcus granulosus | expressed conserved protein | 0.0047 | 0.0012 | 0.0033 |
Echinococcus multilocularis | suppressor of cytokine signaling 7 | 0.0047 | 0.0012 | 0.0033 |
Echinococcus multilocularis | synaptic glycoprotein sc2 | 0.0412 | 0.1144 | 0.3186 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0067 | 0.0073 | 0.0157 |
Schistosoma mansoni | ATP synthase gamma subunit | 0.0108 | 0.02 | 0.0557 |
Schistosoma mansoni | ATP synthase beta subunit | 0.0074 | 0.0095 | 0.0265 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0312 | 0.0834 | 0.1796 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.006 | 0.0053 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0053 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Leishmania major | ATP synthase, epsilon chain, putative | 0.0135 | 0.0285 | 0.0615 |
Mycobacterium ulcerans | F0F1 ATP synthase subunit A | 0.0382 | 0.105 | 0.0972 |
Leishmania major | ATPase alpha subunit | 0.0135 | 0.0285 | 0.0613 |
Plasmodium vivax | polyprenol reductase, putative | 0.0412 | 0.1144 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0312 | 0.0834 | 0.1796 |
Schistosoma mansoni | tyrosine kinase | 0.1153 | 0.3446 | 0.9592 |
Trypanosoma brucei | mitogen-activated protein kinase 3, putative | 0.0678 | 0.1972 | 0.4247 |
Schistosoma mansoni | signal transduction protein lnk-related | 0.0047 | 0.0012 | 0.0033 |
Leishmania major | ATPase alpha subunit | 0.0135 | 0.0285 | 0.0613 |
Mycobacterium leprae | PROBABLE ATP SYNTHASE ALPHA CHAIN ATPA | 0.016 | 0.0362 | 0.0166 |
Echinococcus granulosus | c src tyrosine kinase | 0.008 | 0.0114 | 0.0318 |
Echinococcus multilocularis | c src tyrosine kinase | 0.008 | 0.0114 | 0.0318 |
Echinococcus granulosus | ATP synthase subunit alpha mitochondrial | 0.016 | 0.0362 | 0.1007 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.026 | 0.0674 | 0.1452 |
Mycobacterium tuberculosis | Probable ATP synthase beta chain AtpD | 0.0171 | 0.0395 | 0.0199 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0217 | 0.0539 | 0.15 |
Plasmodium falciparum | polyprenol reductase, putative | 0.0412 | 0.1144 | 1 |
Brugia malayi | RhoGAP domain containing protein | 0.0047 | 0.0012 | 0.0026 |
Echinococcus multilocularis | ATP synthase subunit delta, mitochondrial | 0.0135 | 0.0285 | 0.0795 |
Trypanosoma cruzi | ATPase subunit 9, putative | 0.0114 | 0.0219 | 0.0472 |
Schistosoma mansoni | tyrosine kinase | 0.008 | 0.0114 | 0.0318 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0067 | 0.0073 | 0.0157 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0047 | 0.0012 | 0.0026 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.006 | 0.0053 | 0.0114 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0412 | 0.1144 | 0.2465 |
Plasmodium vivax | ATP synthase alpha chain, putative | 0.016 | 0.0362 | 0.3161 |
Echinococcus multilocularis | 0.0047 | 0.0012 | 0.0033 | |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0067 | 0.0073 | 0.0203 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0412 | 0.1144 | 0.3186 |
Brugia malayi | Tensin | 0.0047 | 0.0012 | 0.0026 |
Brugia malayi | Protein kinase domain containing protein | 0.006 | 0.0053 | 0.0114 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0412 | 0.1144 | 0.2465 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.006 | 0.0053 | 0.0114 |
Schistosoma mansoni | ATP synthase F0 subunit 6 | 0.023 | 0.058 | 0.1615 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0237 | 0.06 | 0.1671 |
Brugia malayi | Variant SH3 domain containing protein | 0.0047 | 0.0012 | 0.0026 |
Toxoplasma gondii | ATP synthase beta subunit ATP-B | 0.0074 | 0.0095 | 0.0205 |
Schistosoma mansoni | hypothetical protein | 0.0202 | 0.0492 | 0.1369 |
Plasmodium falciparum | ATP synthase subunit gamma, mitochondrial | 0.0108 | 0.02 | 0.1747 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0412 | 0.1144 | 0.2465 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0678 | 0.1972 | 0.549 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.017 | 0.0393 | 0.1093 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.12 | 0.3592 | 1 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.006 | 0.0053 | 0.0147 |
Echinococcus multilocularis | ATP synthase subunit alpha, mitochondrial | 0.016 | 0.0362 | 0.1007 |
Brugia malayi | Protein kinase domain containing protein | 0.006 | 0.0053 | 0.0114 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.12 | 0.3592 | 1 |
Schistosoma mansoni | tensin | 0.0047 | 0.0012 | 0.0033 |
Trypanosoma brucei | ATP synthase subunit beta, mitochondrial | 0.0074 | 0.0095 | 0.0205 |
Schistosoma mansoni | adapter molecule crk | 0.0067 | 0.0073 | 0.0203 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0047 | 0.0012 | 0.0033 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.026 | 0.0674 | 0.1452 |
Onchocerca volvulus | ATP synthase subunit alpha, mitochondrial homolog | 0.016 | 0.0362 | 0.3089 |
Trichomonas vaginalis | CMGC family protein kinase | 0.026 | 0.0674 | 0.1452 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0237 | 0.06 | 0.1671 |
Echinococcus multilocularis | protein kinase shaggy | 0.026 | 0.0674 | 0.1877 |
Onchocerca volvulus | 0.006 | 0.0053 | 0.0363 | |
Echinococcus granulosus | tyrosine kinase | 0.006 | 0.0053 | 0.0147 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0237 | 0.06 | 0.1671 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.006 | 0.0053 | 0.0114 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.026 | 0.0674 | 0.5891 |
Brugia malayi | SH2 domain containing protein | 0.0047 | 0.0012 | 0.0026 |
Plasmodium vivax | ATP synthase lipid-binding protein, mitochondrial precursor, putative | 0.0114 | 0.0219 | 0.1915 |
Entamoeba histolytica | protein kinase, putative | 0.017 | 0.0393 | 0.0845 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0052 | 0.0027 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0412 | 0.1144 | 0.2465 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.006 | 0.0053 | 0.0114 |
Toxoplasma gondii | ATP synthase F1 gamma subunit | 0.0108 | 0.02 | 0.0431 |
Brugia malayi | Protein kinase domain containing protein | 0.006 | 0.0053 | 0.0114 |
Entamoeba histolytica | 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein | 0.0412 | 0.1144 | 0.2465 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.006 | 0.0053 | 0.0114 |
Echinococcus granulosus | 5'partial|ATP synthase subunit delta mitochondrial | 0.0135 | 0.0285 | 0.0795 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.1538 | 0.4643 | 1 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0217 | 0.0539 | 0.15 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0047 | 0.0012 | 0.0033 |
Trypanosoma cruzi | ATP synthase subunit beta, mitochondrial, putative | 0.0074 | 0.0095 | 0.0205 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0205 | 0.0501 | 0.1079 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0012 | 0.0033 |
Wolbachia endosymbiont of Brugia malayi | ATP synthase F0F1 subunit epsilon | 0.0135 | 0.0285 | 0.1051 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0237 | 0.06 | 0.1671 |
Brugia malayi | SH2 domain containing protein | 0.0047 | 0.0012 | 0.0026 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0205 | 0.0501 | 0.1079 |
Brugia malayi | hypothetical protein | 0.006 | 0.0053 | 0.0114 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0204 | 0.0498 | 0.1386 |
Echinococcus multilocularis | ATP synthase subunit beta, mitochondrial | 0.0074 | 0.0095 | 0.0265 |
Trypanosoma cruzi | ATP synthase F1 subunit gamma protein, putative | 0.0108 | 0.02 | 0.0431 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0412 | 0.1144 | 0.3186 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.006 | 0.0053 | 0.0114 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.026 | 0.0674 | 0.5891 |
Echinococcus granulosus | N chimaerin | 0.0047 | 0.0012 | 0.0033 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0237 | 0.06 | 0.1671 |
Echinococcus granulosus | guanine nucleotide exchange factor VAV2 | 0.0047 | 0.0012 | 0.0033 |
Echinococcus multilocularis | tensin | 0.0047 | 0.0012 | 0.0033 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0412 | 0.1144 | 0.2465 |
Echinococcus granulosus | SH2 domain containing protein 7 | 0.0047 | 0.0012 | 0.0033 |
Echinococcus multilocularis | phosphatidylinositol 3 kinase regulatory subunit | 0.0047 | 0.0012 | 0.0033 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0205 | 0.0501 | 0.1079 |
Brugia malayi | ATP synthase alpha chain, mitochondrial precursor, putative | 0.016 | 0.0362 | 0.0779 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0067 | 0.0073 | 0.0203 |
Echinococcus multilocularis | SH2 domain containing protein 7 | 0.0047 | 0.0012 | 0.0033 |
Trypanosoma brucei | Mitochondrial ATP synthase subunit c-1 | 0.0114 | 0.0219 | 0.0472 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0205 | 0.0501 | 0.4319 |
Echinococcus multilocularis | suppressor of cytokine signaling 7 | 0.0047 | 0.0012 | 0.0033 |
Echinococcus granulosus | mitogen activated protein kinase 11 | 0.0678 | 0.1972 | 0.549 |
Echinococcus multilocularis | SH2 motif | 0.0047 | 0.0012 | 0.0033 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.006 | 0.0053 | 0.0114 |
Echinococcus granulosus | tensin | 0.0047 | 0.0012 | 0.0033 |
Echinococcus granulosus | tyrosine kinase | 0.0217 | 0.0539 | 0.15 |
Wolbachia endosymbiont of Brugia malayi | ATP synthase F0F1 subunit alpha | 0.016 | 0.0362 | 0.1473 |
Brugia malayi | SH2 domain containing protein | 0.0047 | 0.0012 | 0.0026 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0237 | 0.06 | 0.1671 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.006 | 0.0053 | 0.0114 |
Echinococcus granulosus | tensin C1 domain containing phosphatase | 0.0047 | 0.0012 | 0.0033 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0394 | 0.1091 | 0.2349 |
Schistosoma mansoni | glycogen synthase kinase 3-related (gsk3) (cmgc group III) | 0.026 | 0.0674 | 0.1877 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0217 | 0.0539 | 0.15 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0412 | 0.1144 | 0.2465 |
Brugia malayi | ATP synthase gamma chain, mitochondrial precursor, putative | 0.0108 | 0.02 | 0.0431 |
Mycobacterium leprae | PROBABLE ATP SYNTHASE B CHAIN ATPF | 0.3237 | 0.9921 | 1 |
Toxoplasma gondii | ATP synthase F0 subunit 9, putative | 0.0114 | 0.0219 | 0.0472 |
Schistosoma mansoni | ATP synthase delta chain mitochondrial | 0.0135 | 0.0285 | 0.0795 |
Echinococcus multilocularis | guanine nucleotide exchange factor VAV2 | 0.0047 | 0.0012 | 0.0033 |
Brugia malayi | ATP synthase delta chain, mitochondrial precursor, putative | 0.0135 | 0.0285 | 0.0615 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0312 | 0.0834 | 0.1796 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.005 | 0.0107 |
Echinococcus granulosus | phosphatidylinositol 3 kinase regulatory subunit | 0.0047 | 0.0012 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Trypanosoma cruzi | ATP synthase, epsilon chain, putative | 0.0135 | 0.0285 | 0.0615 |
Echinococcus multilocularis | SH2 motif | 0.0047 | 0.0012 | 0.0033 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0312 | 0.0834 | 0.1796 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.006 | 0.0053 | 0.0114 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0412 | 0.1144 | 0.2465 |
Brugia malayi | SH2 domain containing protein | 0.0047 | 0.0012 | 0.0026 |
Trypanosoma cruzi | glycogen synthase kinase 3, putative | 0.026 | 0.0674 | 0.1452 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Schistosoma mansoni | tyrosine kinase | 0.008 | 0.0114 | 0.0318 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0047 | 0.0012 | 0.0026 |
Echinococcus granulosus | suppressor of cytokine signaling 7 | 0.0047 | 0.0012 | 0.0033 |
Echinococcus multilocularis | N chimaerin | 0.0047 | 0.0012 | 0.0033 |
Entamoeba histolytica | SH2 domain containing protein | 0.0047 | 0.0012 | 0.0026 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0412 | 0.1144 | 0.2465 |
Mycobacterium leprae | PROBABLE ATP SYNTHASE DELTA CHAIN ATPH | 0.0682 | 0.1984 | 0.1835 |
Brugia malayi | SH2 domain containing protein | 0.006 | 0.0053 | 0.0114 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0047 | 0.0012 | 0.0026 |
Leishmania major | ATPase beta subunit, putative | 0.0074 | 0.0095 | 0.0205 |
Leishmania major | mitogen-activated protein kinase 3, putative,map kinase 3, putative | 0.0678 | 0.1972 | 0.4247 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0205 | 0.0501 | 0.1079 |
Mycobacterium ulcerans | F0F1 ATP synthase subunit alpha | 0.016 | 0.0362 | 0.0271 |
Brugia malayi | SH2 domain containing protein | 0.0047 | 0.0012 | 0.0026 |
Brugia malayi | P38 map kinase family protein 2 | 0.0678 | 0.1972 | 0.4247 |
Loa Loa (eye worm) | STAT protein | 0.0047 | 0.0012 | 0.0026 |
Wolbachia endosymbiont of Brugia malayi | ATP synthase F0F1 subunit A | 0.0382 | 0.105 | 0.528 |
Echinococcus multilocularis | ATP synthase gamma subunit | 0.0108 | 0.02 | 0.0557 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.017 | 0.0393 | 0.1093 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0067 | 0.0073 | 0.0157 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0237 | 0.06 | 0.1671 |
Entamoeba histolytica | protein kinase domain containing protein | 0.026 | 0.0674 | 0.1452 |
Mycobacterium tuberculosis | Probable ATP synthase C chain AtpE (lipid-binding protein) (dicyclohexylcarbodiimide-binding protein) | 0.0114 | 0.0219 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Mycobacterium ulcerans | F0F1 ATP synthase subunit delta | 0.0682 | 0.1984 | 0.1922 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0216 | 0.0535 | 0.1153 |
Plasmodium vivax | hypothetical protein, conserved | 0.0135 | 0.0285 | 0.2494 |
Schistosoma mansoni | tensin | 0.0047 | 0.0012 | 0.0033 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0312 | 0.0834 | 0.1796 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.008 | 0.0114 | 0.0318 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0237 | 0.06 | 0.1671 |
Trypanosoma cruzi | ATPase subunit 9, putative | 0.0114 | 0.0219 | 0.0472 |
Schistosoma mansoni | tensin-related | 0.0047 | 0.0012 | 0.0033 |
Plasmodium falciparum | ATP synthase subunit C, putative | 0.0114 | 0.0219 | 0.1915 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0047 | 0.0012 | 0.0033 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.1538 | 0.4643 | 1 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.1538 | 0.4643 | 1 |
Echinococcus multilocularis | NCK adaptor protein | 0.0067 | 0.0073 | 0.0203 |
Entamoeba histolytica | protein kinase domain containing protein | 0.026 | 0.0674 | 0.1452 |
Giardia lamblia | Kinase, CMGC GSK | 0.026 | 0.0674 | 0.5891 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0067 | 0.0073 | 0.0203 |
Schistosoma mansoni | tyrosine kinase | 0.006 | 0.0053 | 0.0147 |
Mycobacterium leprae | PROBABLE ATP SYNTHASE BETA CHAIN ATPD | 0.0171 | 0.0395 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0073 | 0.0157 |
Toxoplasma gondii | ATP synthase, putative | 0.0135 | 0.0285 | 0.0615 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.1538 | 0.4643 | 1 |
Echinococcus granulosus | NCK adaptor protein | 0.0067 | 0.0073 | 0.0203 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0312 | 0.0834 | 0.1796 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Trypanosoma brucei | protein kinase, putative | 0.026 | 0.0674 | 0.1452 |
Brugia malayi | tRNA modification GTPase TrmE family protein | 0.0047 | 0.0012 | 0.0026 |
Mycobacterium leprae | PROBABLE ATP SYNTHASE A CHAIN ATPB (PROTEIN 6) | 0.0382 | 0.105 | 0.0875 |
Brugia malayi | intracellular kinase | 0.026 | 0.0674 | 0.1452 |
Plasmodium vivax | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0412 | 0.1144 | 1 |
Leishmania major | ATPase beta subunit, putative | 0.0074 | 0.0095 | 0.0205 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0237 | 0.06 | 0.1671 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0678 | 0.1972 | 0.4247 |
Schistosoma mansoni | GTPase activating protein | 0.0047 | 0.0012 | 0.0033 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0412 | 0.1144 | 0.2465 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.008 | 0.0114 | 0.0318 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0059 | 0.005 | 0.0107 |
Echinococcus multilocularis | signal transduction protein lnk realted | 0.0047 | 0.0012 | 0.0033 |
Onchocerca volvulus | 0.006 | 0.0053 | 0.0363 | |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0394 | 0.1091 | 0.2349 |
Trypanosoma cruzi | ATPase subunit 9, putative | 0.0114 | 0.0219 | 0.0472 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.1538 | 0.4643 | 1 |
Wolbachia endosymbiont of Brugia malayi | ATP synthase F0F1 subunit gamma | 0.0108 | 0.02 | 0.0578 |
Echinococcus granulosus | ATP synthase gamma subunit | 0.0108 | 0.02 | 0.0557 |
Plasmodium vivax | ATP synthase subunit beta, mitochondrial, putative | 0.0074 | 0.0095 | 0.0833 |
Schistosoma mansoni | ATP synthase alpha subunit mitochondrial | 0.016 | 0.0362 | 0.1007 |
Plasmodium falciparum | ATP synthase F1, alpha subunit | 0.016 | 0.0362 | 0.3161 |
Onchocerca volvulus | 0.0412 | 0.1144 | 1 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0312 | 0.0834 | 0.1796 |
Echinococcus multilocularis | SHC transforming protein 3 | 0.0047 | 0.0012 | 0.0033 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.006 | 0.0053 | 0.0147 |
Schistosoma mansoni | ATP synthase gamma subunit | 0.0108 | 0.02 | 0.0557 |
Echinococcus multilocularis | tensin | 0.0047 | 0.0012 | 0.0033 |
Schistosoma mansoni | shc transforming protein | 0.0047 | 0.0012 | 0.0033 |
Brugia malayi | Variant SH3 domain containing protein | 0.0047 | 0.0012 | 0.0026 |
Echinococcus granulosus | 3 oxo 5 alpha steroid 4 dehydrogenase C terminal | 0.0412 | 0.1144 | 0.3186 |
Schistosoma mansoni | suppressor of cytokine signaling | 0.0047 | 0.0012 | 0.0033 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0412 | 0.1144 | 0.2465 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0237 | 0.06 | 0.1671 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0047 | 0.0012 | 0.0026 |
Schistosoma mansoni | tensin-related | 0.0047 | 0.0012 | 0.0033 |
Mycobacterium ulcerans | hypothetical protein | 0.1538 | 0.4643 | 0.4629 |
Trypanosoma brucei | hypothetical protein | 0.0099 | 0.0174 | 0.0375 |
Schistosoma mansoni | tensin | 0.0047 | 0.0012 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.1538 | 0.4643 | 1 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.006 | 0.0053 | 0.0147 |
Onchocerca volvulus | 0.006 | 0.0053 | 0.0363 | |
Brugia malayi | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 0.1538 | 0.4643 | 1 |
Brugia malayi | SH2 domain containing protein | 0.0047 | 0.0012 | 0.0026 |
Schistosoma mansoni | tyrosine kinase | 0.12 | 0.3592 | 1 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0394 | 0.1091 | 0.2349 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0217 | 0.0539 | 0.15 |
Treponema pallidum | flagellum-specific ATP synthase (fliI) | 0.0074 | 0.0095 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.026 | 0.0674 | 0.1452 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0678 | 0.1972 | 0.4247 |
Giardia lamblia | Kinase, CMGC GSK | 0.026 | 0.0674 | 0.5891 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0012 | 0.0026 |
Mycobacterium tuberculosis | Probable ATP synthase B chain AtpF | 0.3237 | 0.9921 | 0.9919 |
Leishmania major | 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein | 0.1538 | 0.4643 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | 0 M | Inhibitory activity against Glucosylceramidase in mouse liver at a concentration of 10e-4 M; NA is inactive | ChEMBL. | 10386923 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.