Detailed information for compound 518613

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 405.489 | Formula: C24H27N3O3
  • H donors: 3 H acceptors: 3 LogP: 3.92 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C1=C(O)C(NC1=O)CCc1ccccc1)Nc1ccc(cc1)N1CCCCC1
  • InChi: 1S/C24H27N3O3/c28-22-20(14-9-17-7-3-1-4-8-17)26-24(30)21(22)23(29)25-18-10-12-19(13-11-18)27-15-5-2-6-16-27/h1,3-4,7-8,10-13,20,28H,2,5-6,9,14-16H2,(H,25,29)(H,26,30)
  • InChiKey: MGOWFSPLAUIYQB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Undecaprenyl pyrophosphate synthase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania infantum cis-prenyltransferase-like protein Get druggable targets OG5_126777 All targets in OG5_126777
Plasmodium falciparum dehydrodolichyl diphosphate synthetase, putative Get druggable targets OG5_126777 All targets in OG5_126777
Echinococcus granulosus dehydrodolichyl diphosphate synthase Get druggable targets OG5_126777 All targets in OG5_126777
Wolbachia endosymbiont of Brugia malayi undecaprenyl pyrophosphate synthase Get druggable targets OG5_126777 All targets in OG5_126777
Mycobacterium ulcerans undecaprenyl pyrophosphate synthase Get druggable targets OG5_126777 All targets in OG5_126777
Candida albicans cis-prenyltransferase-like orf Get druggable targets OG5_126777 All targets in OG5_126777
Candida albicans cis-prenyltransferase-like orf Get druggable targets OG5_126777 All targets in OG5_126777
Schistosoma japonicum ko:K00810 dehydrodolichyl diphosphate synthase [EC:2.5.1.-], putative Get druggable targets OG5_126777 All targets in OG5_126777
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126777 All targets in OG5_126777
Mycobacterium tuberculosis Long (C50) chain Z-isoprenyl diphosphate synthase (Z-decaprenyl diphosphate synthase) Get druggable targets OG5_126777 All targets in OG5_126777
Trypanosoma congolense cis-prenyltransferase-like protein, putative Get druggable targets OG5_126777 All targets in OG5_126777
Toxoplasma gondii undecaprenyl diphosphate synthase Get druggable targets OG5_126777 All targets in OG5_126777
Giardia lamblia Undecaprenyl pyrophosphate synthase Get druggable targets OG5_126777 All targets in OG5_126777
Leishmania braziliensis cis-prenyltransferase-like protein Get druggable targets OG5_126777 All targets in OG5_126777
Brugia malayi Undecaprenyl diphosphate synthase family protein Get druggable targets OG5_126777 All targets in OG5_126777
Mycobacterium leprae SHORT (C15) CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHASE (Z-FPP SYNTHASE) (Z-FARNESYL DIPHOSPHATE SYNTHASE) (Z-FPP SYNTHETASE) (Z-FARN Get druggable targets OG5_126777 All targets in OG5_126777
Theileria parva undecaprenyl diphosphate synthase, putative Get druggable targets OG5_126777 All targets in OG5_126777
Neospora caninum GF20994, related Get druggable targets OG5_126777 All targets in OG5_126777
Onchocerca volvulus Dehydrodolichyl diphosphate synthase homolog Get druggable targets OG5_126777 All targets in OG5_126777
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126777 All targets in OG5_126777
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126777 All targets in OG5_126777
Candida albicans Cis-prenyltransferase Get druggable targets OG5_126777 All targets in OG5_126777
Leishmania major cis-prenyltransferase-like protein Get druggable targets OG5_126777 All targets in OG5_126777
Candida albicans Cis-prenyltransferase Get druggable targets OG5_126777 All targets in OG5_126777
Plasmodium vivax dehydrodolichyl diphosphate synthetase, putative Get druggable targets OG5_126777 All targets in OG5_126777
Mycobacterium ulcerans short (C15) chain Z-isoprenyl diphosphate synthase, UppS Get druggable targets OG5_126777 All targets in OG5_126777
Leishmania donovani cis-prenyltransferase-like protein Get druggable targets OG5_126777 All targets in OG5_126777
Mycobacterium ulcerans Z-decaprenyl diphosphate synthase Get druggable targets OG5_126777 All targets in OG5_126777
Plasmodium yoelii undecaprenyl pyrophosphate synthetase-like-related Get druggable targets OG5_126777 All targets in OG5_126777
Plasmodium berghei dehydrodolichyl diphosphate synthetase, putative Get druggable targets OG5_126777 All targets in OG5_126777
Plasmodium knowlesi dehydrodolichyl diphosphate synthetase, putative Get druggable targets OG5_126777 All targets in OG5_126777
Echinococcus multilocularis dehydrodolichyl diphosphate synthase Get druggable targets OG5_126777 All targets in OG5_126777
Schistosoma mansoni dehydrodolichyl diphosphate synthase (dedol-pp synthase) Get druggable targets OG5_126777 All targets in OG5_126777
Trichomonas vaginalis undecaprenyl diphosphate synthase, putative Get druggable targets OG5_126777 All targets in OG5_126777
Mycobacterium leprae Probable Long (C50) chain Z-isoprenyl diphosphate synthase (Z-DECAPRENYL DIPHOSPHATE SYNTHASE) Get druggable targets OG5_126777 All targets in OG5_126777
Mycobacterium tuberculosis Short (C15) chain Z-isoprenyl diphosphate synthase (Z-FPP synthase) (Z-farnesyl diphosphate synthase) (Z-FPP synthetase) (Z-farn Get druggable targets OG5_126777 All targets in OG5_126777
Babesia bovis undecaprenyl pyrophosphate synthetase, putative Get druggable targets OG5_126777 All targets in OG5_126777
Trypanosoma brucei cis-prenyltransferase-like protein Get druggable targets OG5_126777 All targets in OG5_126777
Schistosoma mansoni dehydrodolichyl diphosphate synthase (dedol-pp synthase) Get druggable targets OG5_126777 All targets in OG5_126777
Schistosoma mansoni dehydrodolichyl diphosphate synthase (dedol-pp synthase) Get druggable targets OG5_126777 All targets in OG5_126777
Treponema pallidum undecaprenyl pyrophosphate synthase Get druggable targets OG5_126777 All targets in OG5_126777
Leishmania mexicana cis-prenyltransferase-like protein Get druggable targets OG5_126777 All targets in OG5_126777
Trypanosoma brucei gambiense cis-prenyltransferase-like protein, putative Get druggable targets OG5_126777 All targets in OG5_126777
Chlamydia trachomatis isoprenyl transferase Get druggable targets OG5_126777 All targets in OG5_126777
Trypanosoma cruzi cis-prenyltransferase, putative Get druggable targets OG5_126777 All targets in OG5_126777
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus still life protein homolog Undecaprenyl pyrophosphate synthase   252 aa 233 aa 37.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0459 0.0449
Schistosoma mansoni hypothetical protein 0.0018 0.0086 0.0039
Echinococcus multilocularis musashi 0.0032 0.0339 0.0307
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0038 0.0459 0.071
Trichomonas vaginalis CAMK family protein kinase 0.0313 0.5561 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0261 0.029
Brugia malayi putative amidase 0.0027 0.0246 0.0335
Mycobacterium ulcerans hypothetical protein 0.0057 0.0811 0.1734
Loa Loa (eye worm) beta-lactamase 0.0035 0.04 0.0455
Echinococcus granulosus thyroid hormone receptor alpha 0.0017 0.0059 0.0026
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0289 0.0258
Onchocerca volvulus 0.002 0.0112 0.0096
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Schistosoma mansoni nuclear receptor nhr-48 0.0017 0.0059 0.0001
Onchocerca volvulus 0.0062 0.0898 0.1524
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0243 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0243 0.015
Schistosoma mansoni hypothetical protein 0.0042 0.052 0.0655
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0036 0.0408 0.0496
Schistosoma mansoni notch 0.002 0.0112 0.0076
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0185 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0243 0.015
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0403 0.0371
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.04 0.0442
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0223 0.3883 0.3863
Brugia malayi Amidase family protein 0.0027 0.0246 0.0335
Brugia malayi SET domain containing protein 0.0028 0.0267 0.0371
Schistosoma mansoni hypothetical protein 0.002 0.0112 0.0076
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.4034 0.4014
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0036 0.0408 0.0496
Trichomonas vaginalis bromodomain-containing protein, putative 0.005 0.0683 0.0965
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0035 0.0392 0.0373
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0948 0.1456
Echinococcus granulosus GPCR family 2 0.0018 0.0086 0.0053
Schistosoma mansoni retinoic acid receptor RXR 0.0036 0.0408 0.0496
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0117 0.1928 0.4724
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0818 0.1342
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Brugia malayi PHD-finger family protein 0.0068 0.1013 0.1686
Plasmodium vivax histone acetyltransferase GCN5, putative 0.005 0.0683 0.1598
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0087 0.006
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0028 0.0268 0.0338
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0101 0.0094
Leishmania major sterol C-24 reductase, putative 0.0047 0.0629 0.07
Giardia lamblia Heat shock protein HSP 90-alpha 0.0045 0.0589 0.0875
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0072 0.108 0.105
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0027 0.0243 0.021
Echinococcus granulosus neural cadherin 0.002 0.0112 0.0079
Loa Loa (eye worm) hypothetical protein 0.0031 0.0329 0.0369
Schistosoma mansoni thyroid hormone receptor 0.0036 0.0408 0.0496
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0162 0.0144
Brugia malayi nuclear hormone receptor 0.0036 0.0408 0.062
Echinococcus granulosus protein jagged 1 0.002 0.0112 0.0079
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Brugia malayi GCC2 and GCC3 family protein 0.002 0.0112 0.0099
Echinococcus granulosus neurogenic locus notch protein 0.002 0.0112 0.0079
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0392 0.0976
Plasmodium falciparum glutathione reductase 0.0038 0.0459 0.0944
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Loa Loa (eye worm) DR-78 0.0017 0.0059 0.0044
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.0339 0.0499
Loa Loa (eye worm) hypothetical protein 0.0036 0.0408 0.0465
Brugia malayi Heterochromatin protein 1 0.0163 0.2772 0.4784
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0408 0.0376
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0243 0.015
Echinococcus granulosus lamin dm0 0.0032 0.0339 0.0307
Brugia malayi jmjC domain containing protein 0.0022 0.0156 0.0176
Trypanosoma brucei heat shock protein 84, putative 0.0035 0.0401 0.0411
Mycobacterium leprae PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) 0.0027 0.0246 0.0441
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0027 0.0246 0.0214
Onchocerca volvulus Pyruvate kinase homolog 0.0079 0.1212 0.2095
Brugia malayi Delta serrate ligand family protein 0.002 0.0112 0.0099
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0038 0.0459 0.0476
Echinococcus multilocularis thioredoxin glutathione reductase 0.011 0.18 0.1773
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0017 0.0059 0.0001
Brugia malayi conserved hypotetical protein 0.0017 0.0059 0.0005
Plasmodium falciparum JmjC domain-containing protein, putative 0.0022 0.0156 0.0176
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0392 0.0426
Echinococcus multilocularis bloom syndrome protein 0.0079 0.1225 0.1196
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0243 0.0356
Loa Loa (eye worm) hypothetical protein 0.0036 0.0408 0.0465
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0098 0.1572 0.2148
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0053 0.0735 0.1979
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0017 0.0059 0.0001
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0108 0.175 1
Brugia malayi Pyruvate kinase, M2 isozyme 0.0079 0.1212 0.2035
Mycobacterium tuberculosis Conserved protein 0.0035 0.04 0.0753
Leishmania major hypothetical protein, conserved 0.0035 0.04 0.0446
Echinococcus granulosus lysine specific demethylase 6a 0.0022 0.0156 0.0123
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0033 0.0358 0.0687
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.0027 0.0246 0.0238
Trichomonas vaginalis phosphofructokinase, putative 0.0128 0.2133 0.3651
Echinococcus multilocularis pyruvate kinase 0.0062 0.0903 0.0873
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0019 0.0097 0.0064
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0268 0.0401
Schistosoma mansoni smad1 5 8 and 0.0019 0.0101 0.006
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0036 0.0408 0.0376
Trichomonas vaginalis hypothetical protein 0.0027 0.0243 0.015
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0128 0.2133 0.4273
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0087 0.0116
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0252 0.443 0.8939
Brugia malayi Endoplasmin precursor 0.0053 0.0731 0.1189
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0035 0.0401 0.0369
Loa Loa (eye worm) helicase 0.0027 0.0243 0.0265
Echinococcus multilocularis lysine specific demethylase 5A 0.0082 0.128 0.1251
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0017 0.0059 0.0044
Loa Loa (eye worm) animal heme peroxidase 0.0061 0.0876 0.1028
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0117 0.1928 0.3271
Brugia malayi CHD4 protein 0.0027 0.0243 0.0329
Loa Loa (eye worm) glutathione reductase 0.011 0.18 0.2141
Giardia lamblia Sgs1 DNA helicase, putative 0.0033 0.0358 0.045
Schistosoma mansoni hypothetical protein 0.002 0.0112 0.0076
Brugia malayi nuclear hormone receptor family member odr-7 0.0017 0.0059 0.0005
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0057 0.0811 0.1734
Mycobacterium tuberculosis Probable oxidoreductase 0.028 0.4953 1
Trypanosoma cruzi monoglyceride lipase, putative 0.023 0.4028 0.4448
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0033 0.0358 0.0875
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0074 0.1115 0.2205
Entamoeba histolytica hypothetical protein 0.0027 0.0243 0.0356
Entamoeba histolytica acyl-coA synthetase, putative 0.0028 0.0268 0.0401
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0038 0.0459 0.1172
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0038 0.0459 0.0829
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0028 0.027 0.0377
Onchocerca volvulus Huntingtin homolog 0.0264 0.4657 0.8357
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Echinococcus granulosus heat shock protein 0.0053 0.0731 0.07
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0162 0.0269
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.0392 0.1608
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Echinococcus multilocularis neurogenic locus notch protein 4 0.002 0.0112 0.0079
Brugia malayi MH2 domain containing protein 0.0019 0.0101 0.0079
Schistosoma mansoni Lamin B receptor (ERG24) 0.0047 0.0629 0.081
Brugia malayi EGF-like domain containing protein 0.002 0.0112 0.0099
Brugia malayi beta-lactamase 0.0035 0.04 0.0606
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0087 0.004
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0117 0.1928 0.547
Trichomonas vaginalis conserved hypothetical protein 0.023 0.4028 0.7162
Loa Loa (eye worm) pyruvate kinase 0.0079 0.1212 0.1432
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0589 0.0595
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0027 0.0243 0.021
Echinococcus multilocularis jumonji domain containing protein 0.0095 0.1509 0.1481
Echinococcus granulosus L aminoadipate semialdehyde 0.0098 0.1572 0.1544
Schistosoma mansoni lamin 0.0032 0.0339 0.0399
Loa Loa (eye worm) transcription factor SMAD2 0.0279 0.4931 0.5911
Echinococcus granulosus notch 0.002 0.0112 0.0079
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0033 0.0358 0.0325
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.0027 0.0246 0.0441
Treponema pallidum NADH oxidase 0.0038 0.0459 0.1931
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0818 0.0958
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0313 0.5561 0.667
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0268 0.0484
Treponema pallidum undecaprenyl pyrophosphate synthase 0.0026 0.0225 0.0802
Onchocerca volvulus Peroxidasin homolog 0.0061 0.0876 0.1485
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0027 0.0246 0.0267
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0087 0.0078
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0086 0.0053
Trichomonas vaginalis valacyclovir hydrolase, putative 0.023 0.4028 0.7162
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0036 0.0408 0.0376
Echinococcus multilocularis PHD finger protein rhinoceros 0.0068 0.1013 0.0983
Leishmania major hypothetical protein, conserved 0.0497 0.8983 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0087 0.0054
Toxoplasma gondii pyruvate kinase PyKII 0.004 0.0499 0.1289
Loa Loa (eye worm) hypothetical protein 0.0026 0.0225 0.0244
Mycobacterium ulcerans hypothetical protein 0.0057 0.0811 0.1734
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Mycobacterium tuberculosis Conserved protein 0.0035 0.04 0.0753
Echinococcus multilocularis neurogenic locus notch protein 0.002 0.0112 0.0079
Plasmodium falciparum heat shock protein 90 0.0053 0.0731 0.1635
Loa Loa (eye worm) nuclear receptor NHR-67 0.0017 0.0059 0.0044
Loa Loa (eye worm) hypothetical protein 0.0036 0.0408 0.0465
Mycobacterium tuberculosis Possible lysophospholipase 0.023 0.4028 0.8122
Trichomonas vaginalis endoplasmin, putative 0.0038 0.0462 0.0555
Loa Loa (eye worm) hypothetical protein 0.0036 0.0408 0.0465
Toxoplasma gondii aldehyde dehydrogenase 0.0072 0.108 0.299
Loa Loa (eye worm) hypothetical protein 0.0462 0.8326 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0243 0.0356
Echinococcus granulosus pyruvate kinase 0.004 0.0499 0.0467
Onchocerca volvulus 0.0035 0.04 0.062
Trypanosoma cruzi heat shock protein 90, putative 0.0022 0.016 0.0113
Brugia malayi hypothetical protein 0.0017 0.0059 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0036 0.0408 0.062
Loa Loa (eye worm) hypothetical protein 0.0032 0.0339 0.0382
Echinococcus multilocularis Chromobox protein 3 0.0027 0.0243 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0243 0.015
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0268 0.0373
Schistosoma mansoni hypothetical protein 0.034 0.607 0.8533
Echinococcus multilocularis heat shock protein 0.0053 0.0731 0.07
Loa Loa (eye worm) jmjC domain-containing protein 0.0141 0.2361 0.2816
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0408 0.0376
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0036 0.0408 0.0376
Echinococcus granulosus lamin b receptor 0.0047 0.0629 0.0598
Schistosoma mansoni DNA polymerase eta 0.0022 0.0162 0.0147
Mycobacterium ulcerans aldehyde dehydrogenase 0.0072 0.108 0.2425
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.1443 0.2373
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0098 0.1572 0.2749
Echinococcus granulosus jumonji domain containing protein 0.0095 0.1509 0.1481
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0097 0.0071
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0022 0.0161 0.0301
Schistosoma mansoni jumonji/arid domain-containing protein 0.0082 0.128 0.1733
Mycobacterium ulcerans short (C15) chain Z-isoprenyl diphosphate synthase, UppS 0.0026 0.0225 0.0227
Loa Loa (eye worm) intermediate filament protein 0.0032 0.0339 0.0382
Echinococcus multilocularis pyruvate kinase 0.004 0.0499 0.0467
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0057 0.0811 0.1203
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0243 0.015
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0087 0.0054
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.028 0.4953 1
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.023 0.4028 0.7162
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0459 0.0449
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.023 0.4028 0.7221
Trypanosoma cruzi polo-like protein kinase, putative 0.0313 0.5561 0.6165
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0033 0.0358 0.0404
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0038 0.0459 0.5249
Toxoplasma gondii PHD-finger domain-containing protein 0.0068 0.1013 0.2794
Echinococcus multilocularis lamin 0.0032 0.0339 0.0307
Mycobacterium tuberculosis Probable reductase 0.0252 0.443 0.8939
Loa Loa (eye worm) hypothetical protein 0.0264 0.4657 0.5581
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0403 0.0489
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0057 0.0811 0.1734
Onchocerca volvulus 0.0028 0.0268 0.0379
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0036 0.0408 0.0376
Loa Loa (eye worm) hypothetical protein 0.0322 0.5734 0.6878
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0036 0.0408 0.0376
Brugia malayi EGF-like domain containing protein 0.002 0.0115 0.0104
Plasmodium falciparum endoplasmin, putative 0.0038 0.0462 0.0951
Plasmodium falciparum heat shock protein 90, putative 0.0201 0.3476 0.8598
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0035 0.0401 0.0621
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0097 0.0071
Loa Loa (eye worm) hypothetical protein 0.04 0.7184 0.8625
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0162 0.0116
Loa Loa (eye worm) hypothetical protein 0.0039 0.0479 0.055
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0027 0.0243 0.0539
Loa Loa (eye worm) steroid hormone receptor 0.0036 0.0408 0.0465
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0038 0.0459 0.0829
Echinococcus granulosus jumonji domain containing 1A 0.0022 0.0156 0.0123
Schistosoma mansoni lamin 0.0032 0.0339 0.0399
Mycobacterium leprae Probable lipase LipE 0.0035 0.04 0.0753
Schistosoma mansoni hypothetical protein 0.002 0.0112 0.0076
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0036 0.0408 0.0496
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0403 0.1007
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0392 0.0774
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.4034 0.4014
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0313 0.5561 0.5546
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.04 0.0606
Schistosoma mansoni hypothetical protein 0.0396 0.7104 1
Trypanosoma brucei monoglyceride lipase, putative 0.023 0.4028 0.4464
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.04 0.0455
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.04 0.0753
Onchocerca volvulus Huntingtin homolog 0.0264 0.4657 0.8357
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0252 0.443 0.8939
Brugia malayi hypothetical protein 0.0019 0.0097 0.0071
Plasmodium falciparum pyruvate kinase 2 0.004 0.0499 0.1046
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0156 0.0123
Leishmania major heat shock protein, putative 0.0035 0.0401 0.0447
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0038 0.0459 0.0944
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0091 0.1443 0.2515
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0392 0.1585
Loa Loa (eye worm) hypothetical protein 0.0022 0.0161 0.0167
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0162 0.018
Onchocerca volvulus 0.0061 0.0876 0.1485
Loa Loa (eye worm) pyruvate kinase 0.0079 0.1212 0.1432
Toxoplasma gondii heat shock protein HSP90 0.0053 0.0731 0.1969
Plasmodium falciparum pyruvate kinase 0.0079 0.1212 0.2854
Echinococcus multilocularis pyruvate kinase 0.004 0.0499 0.0467
Brugia malayi Pre-SET motif family protein 0.0246 0.4315 0.7501
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0028 0.0268 0.0338
Echinococcus multilocularis pyruvate kinase 0.0079 0.1212 0.1182
Plasmodium vivax JmjC domain containing protein 0.0022 0.0156 0.0275
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0392 0.0426
Echinococcus granulosus peregrin 0.0072 0.1091 0.1062
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0313 0.5561 0.5546
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0392 0.0426
Schistosoma mansoni hypothetical protein 0.0039 0.0479 0.0597
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0289 0.0512
Entamoeba histolytica hypothetical protein 0.0042 0.052 0.0858
Schistosoma mansoni jumonji/arid domain-containing protein 0.0082 0.128 0.1733
Mycobacterium ulcerans heat shock protein 90 0.005 0.0671 0.1373
Brugia malayi MH1 domain containing protein 0.0019 0.0101 0.0079
Trichomonas vaginalis chromobox protein, putative 0.0027 0.0243 0.015
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0319 0.0292
Loa Loa (eye worm) hypothetical protein 0.0035 0.0403 0.0458
Loa Loa (eye worm) jmjC domain-containing protein 0.0082 0.128 0.1514
Brugia malayi Muscleblind-like protein 0.0322 0.5734 1
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0243 0.0492
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0043
Echinococcus granulosus dna polymerase eta 0.0022 0.0162 0.0129
Brugia malayi Animal haem peroxidase family protein 0.0061 0.0876 0.1445
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0289 0.0608
Echinococcus multilocularis neurogenic locus protein delta 0.002 0.0112 0.0079
Echinococcus granulosus geminin 0.0396 0.7104 0.7094
Loa Loa (eye worm) hypothetical protein 0.0021 0.0136 0.0137
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Echinococcus multilocularis dehydrodolichyl diphosphate synthase 0.0026 0.0225 0.0192
Trypanosoma cruzi pyruvate kinase 2, putative 0.0079 0.1212 0.1292
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.0027 0.0246 0.0441
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Echinococcus multilocularis endoplasmin 0.005 0.0671 0.064
Echinococcus granulosus protein jagged 1 0.002 0.0112 0.0079
Onchocerca volvulus Bile acid receptor homolog 0.0036 0.0408 0.0634
Loa Loa (eye worm) hypothetical protein 0.0036 0.0408 0.0465
Loa Loa (eye worm) animal heme peroxidase 0.0061 0.0876 0.1028
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0162 0.0129
Echinococcus multilocularis lysine specific demethylase 6a 0.0022 0.0156 0.0123
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Echinococcus granulosus pyruvate kinase 0.004 0.0499 0.0467
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0171 0.2928 0.2905
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0265
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.028 0.4953 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0223 0.3893 0.3873
Loa Loa (eye worm) hypothetical protein 0.0021 0.0136 0.0137
Mycobacterium ulcerans aldehyde dehydrogenase 0.0072 0.108 0.2425
Loa Loa (eye worm) Notch2 0.002 0.0112 0.0108
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0038 0.0459 0.0511
Echinococcus granulosus chromobox protein 2 0.0027 0.0243 0.021
Leishmania major trypanothione reductase 0.011 0.18 0.2004
Brugia malayi notch-like transmembrane receptor 0.002 0.0112 0.0099
Plasmodium falciparum histone acetyltransferase GCN5 0.0046 0.0605 0.1315
Trypanosoma brucei cis-prenyltransferase-like protein 0.0026 0.0225 0.0214
Schistosoma mansoni coup transcription factor 0.0036 0.0408 0.0496
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0268 0.0373
Brugia malayi hypothetical protein 0.0027 0.0243 0.0329
Brugia malayi hypothetical protein 0.0019 0.0097 0.0072
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0268 0.0373
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Loa Loa (eye worm) nuclear hormone receptor 0.0017 0.0059 0.0044
Echinococcus multilocularis mothers against decapentaplegic 5 0.0019 0.0101 0.0068
Toxoplasma gondii thioredoxin reductase 0.011 0.18 0.5097
Echinococcus multilocularis protein jagged 1 0.002 0.0112 0.0079
Loa Loa (eye worm) 6-phosphofructokinase 0.0128 0.2133 0.2542
Echinococcus multilocularis slit 2 protein 0.002 0.0115 0.0082
Trichomonas vaginalis heat shock protein, putative 0.0053 0.0731 0.1055
Trypanosoma cruzi heat shock protein 85, putative 0.0053 0.0731 0.0754
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Toxoplasma gondii PHD-finger domain-containing protein 0.0022 0.0161 0.0301
Schistosoma mansoni jumonji domain containing protein 0.0022 0.0156 0.0139
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0036 0.0408 0.0376
Plasmodium falciparum esterase, putative 0.023 0.4028 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0019 0.0097 0.0089
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0392 0.0774
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0022 0.0156 0.0137
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0459 0.0449
Brugia malayi 6-phosphofructokinase 0.0128 0.2133 0.3658
Trichomonas vaginalis set domain proteins, putative 0.028 0.4946 0.8861
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0403 0.0371
Echinococcus granulosus lamin 0.0032 0.0339 0.0307
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0243 0.015
Schistosoma mansoni chromobox protein 0.0027 0.0243 0.0261
Plasmodium falciparum dehydrodolichyl diphosphate synthetase, putative 0.0026 0.0225 0.035
Plasmodium vivax heat shock protein, putative 0.0201 0.3476 0.8612
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0087 0.0054
Echinococcus granulosus mothers against decapentaplegic 5 0.0019 0.0101 0.0068
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0027 0.0246 0.0906
Loa Loa (eye worm) hypothetical protein 0.0021 0.0136 0.0137
Loa Loa (eye worm) hypothetical protein 0.0033 0.0358 0.0404
Loa Loa (eye worm) notch protein 0.002 0.0112 0.0108
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0086 0.0053
Plasmodium falciparum lysophospholipase, putative 0.023 0.4028 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0087 0.0054
Loa Loa (eye worm) heat shock protein 75 0.0035 0.0401 0.0456
Trichomonas vaginalis CAMK family protein kinase 0.0313 0.5561 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.04 0.0485
Brugia malayi Animal haem peroxidase family protein 0.0061 0.0876 0.1445
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0042 0.0537 0.0598
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0265
Trichomonas vaginalis heat shock protein, putative 0.0045 0.0589 0.0791
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0265
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0036 0.0408 0.062
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.002 0.0112 0.0076
Schistosoma mansoni slit 0.002 0.0115 0.008
Leishmania major cis-prenyltransferase-like protein 0.0026 0.0225 0.025
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0036 0.0408 0.062
Plasmodium vivax PST-A protein 0.023 0.4028 1
Echinococcus granulosus slit 2 protein 0.002 0.0115 0.0082
Schistosoma mansoni phd/f-box containing protein 0.0022 0.0156 0.0139
Loa Loa (eye worm) heterochromatin protein 1 0.0163 0.2772 0.3312
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0261 0.0592
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0017 0.0059 0.0026
Echinococcus granulosus neurogenic locus notch protein 4 0.002 0.0112 0.0079
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0108 0.175 0.1722
Schistosoma mansoni hypothetical protein 0.0396 0.7104 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0068 0.1013 0.0983
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0028 0.0261 0.032
Trichomonas vaginalis heat shock protein, putative 0.005 0.0671 0.0943
Echinococcus granulosus fibropellin Ia 0.002 0.0112 0.0079
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0117 0.1928 0.4671
Schistosoma mansoni hypothetical protein 0.002 0.0112 0.0076
Schistosoma mansoni nuclear receptor 0.0017 0.0059 0.0001
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0038 0.0459 0.0944
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0068 0.1013 0.1355
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0017 0.0059 0.0026
Schistosoma mansoni dehydrodolichyl diphosphate synthase (dedol-pp synthase) 0.0026 0.0225 0.0236
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0022 0.0156 0.0109
Trichomonas vaginalis chromobox protein, putative 0.0027 0.0243 0.015
Onchocerca volvulus 0.0072 0.1077 0.185
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0243 0.015
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0027 0.0243 0.0261
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0042 0.0537 0.0563
Echinococcus granulosus smad 0.0019 0.0101 0.0068
Loa Loa (eye worm) hypothetical protein 0.0035 0.04 0.0455
Onchocerca volvulus Dehydrodolichyl diphosphate synthase homolog 0.0026 0.0225 0.0301
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0162 0.0116
Plasmodium vivax hypothetical protein, conserved 0.0068 0.1013 0.2428
Schistosoma mansoni aldehyde dehydrogenase 0.0072 0.108 0.145
Plasmodium vivax heat shock protein 90, putative 0.0035 0.0401 0.089
Brugia malayi phosphofructokinase 0.0128 0.2133 0.3658
Loa Loa (eye worm) hypothetical protein 0.0028 0.0268 0.0296
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0028 0.0261 0.047
Brugia malayi Cadherin domain containing protein 0.002 0.0112 0.0099
Schistosoma mansoni hypothetical protein 0.002 0.0112 0.0076
Echinococcus granulosus intermediate filament protein 0.0032 0.0339 0.0307
Brugia malayi Smad1 0.0019 0.0101 0.0079
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0035 0.0401 0.0643
Echinococcus granulosus endoplasmin 0.005 0.0671 0.064
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0252 0.443 0.8939
Plasmodium vivax pyruvate kinase, putative 0.0079 0.1212 0.2926
Brugia malayi nuclear receptor RXR 0.0019 0.0097 0.0071
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0036 0.0408 0.0376
Brugia malayi photoreceptor-specific nuclear receptor 0.0036 0.0408 0.062
Plasmodium falciparum thioredoxin reductase 0.0038 0.0459 0.0944
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0027 0.0243 0.021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0097 0.0089
Schistosoma mansoni pyruvate kinase 0.0079 0.1212 0.1637
Mycobacterium ulcerans amidase 0.0027 0.0246 0.0283
Brugia malayi PHD-finger family protein 0.0022 0.0161 0.0185
Loa Loa (eye worm) hypothetical protein 0.0068 0.1013 0.1193
Onchocerca volvulus Chorion peroxidase homolog 0.0061 0.0876 0.1485
Echinococcus multilocularis ecdysone induced protein 78C 0.0036 0.0408 0.0376
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0028 0.027 0.0377
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0153 0.2597 0.5214
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.0027 0.0246 0.0682
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0086 0.0053
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.023 0.4028 0.7162
Echinococcus granulosus thioredoxin glutathione reductase 0.011 0.18 0.1773
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0162 0.0144
Trichomonas vaginalis glutathione reductase, putative 0.0038 0.0459 0.055
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.04 0.0442
Schistosoma mansoni peroxidasin 0.0061 0.0876 0.1161
Mycobacterium leprae conserved hypothetical protein 0.0028 0.0261 0.047
Loa Loa (eye worm) animal heme peroxidase 0.0061 0.0876 0.1028
Onchocerca volvulus Pyruvate kinase homolog 0.0079 0.1212 0.2095
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0243 0.015
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0028 0.0261 0.0771
Onchocerca volvulus Peroxidase homolog 0.0061 0.0876 0.1485
Mycobacterium tuberculosis Conserved protein 0.0035 0.04 0.0753
Schistosoma mansoni DNA helicase recq5 0.0033 0.0358 0.0424
Echinococcus granulosus 6 phosphofructokinase 0.0128 0.2133 0.2107
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0115 0.0174
Leishmania major DNA polymerase kappa, putative 0.0022 0.0162 0.018
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0156 0.0123
Schistosoma mansoni smad1 5 8 and 0.0019 0.0101 0.006
Echinococcus multilocularis lamin b receptor 0.0047 0.0629 0.0598
Loa Loa (eye worm) hypothetical protein 0.0055 0.0769 0.0899
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0036 0.0408 0.062
Mycobacterium leprae Probable pyruvate kinase PykA 0.0079 0.1212 0.2401
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0162 0.0147
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Schistosoma mansoni hypothetical protein 0.0047 0.0622 0.08
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0162 0.0129
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0252 0.443 0.8939
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0086 0.0053
Giardia lamblia Kinase, PLK 0.0313 0.5561 1
Loa Loa (eye worm) RecQ helicase 0.0079 0.1225 0.1448
Echinococcus granulosus phd:f box containing protein 0.0022 0.0156 0.0123
Brugia malayi Bloom's syndrome protein homolog 0.0079 0.1225 0.2059
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0072 0.108 0.2134
Loa Loa (eye worm) hypothetical protein 0.0015 0.0033 0.0013
Echinococcus granulosus lysine specific demethylase 5A 0.0082 0.128 0.1251
Echinococcus multilocularis dna polymerase eta 0.0022 0.0162 0.0129
Leishmania major C-14 sterol reductase, putative 0.0047 0.0629 0.07
Echinococcus multilocularis neuropeptide s receptor 0.0552 1 1
Echinococcus multilocularis FTZ F1 alpha 0.0036 0.0408 0.0376
Trypanosoma cruzi amidase, putative 0.0027 0.0246 0.0211
Brugia malayi hypothetical protein 0.0231 0.4034 0.7007
Entamoeba histolytica recQ family DNA helicase 0.0017 0.0059 0.0021
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.023 0.4028 0.7162
Echinococcus multilocularis Smad4 0.0019 0.0101 0.0068
Onchocerca volvulus Dual oxidase homolog 0.0061 0.0876 0.1485
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0036 0.0408 0.0496
Brugia malayi ecdysone receptor 0.0017 0.0059 0.0005
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0087 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Trypanosoma brucei unspecified product 0.0022 0.0162 0.0144
Chlamydia trachomatis pyruvate kinase 0.0079 0.1212 0.6666
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0128 0.2133 0.4273
Plasmodium falciparum lysophospholipase, putative 0.023 0.4028 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0136 0.0217
Echinococcus granulosus delta-like protein 1 0.002 0.0112 0.0079
Mycobacterium tuberculosis Probable dehydrogenase 0.0252 0.443 0.8939
Leishmania major DNA polymerase eta, putative 0.0022 0.0162 0.018
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0057 0.0811 0.1588
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0027 0.0243 0.0261
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0035 0.0401 0.0369
Brugia malayi serine/threonine-protein kinase plk-2 0.0313 0.5561 0.9695
Trypanosoma brucei C-14 sterol reductase, putative 0.0047 0.0629 0.0666
Schistosoma mansoni pyruvate kinase 0.004 0.0499 0.0625
Loa Loa (eye worm) hypothetical protein 0.0019 0.0097 0.0089
Echinococcus granulosus chromobox protein 1 0.0163 0.2772 0.2748
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.0027 0.0246 0.0441
Onchocerca volvulus 0.0098 0.1572 0.275
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0038 0.0459 0.0427
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0087 0.0097
Trichomonas vaginalis DNA helicase recq, putative 0.0079 0.1225 0.1969
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0108 0.175 0.8151
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0898 0.1191
Echinococcus granulosus fatty acid amide hydrolase 1 0.0223 0.3883 0.3863
Onchocerca volvulus 0.002 0.0112 0.0096
Schistosoma mansoni phosphatidylserine receptor 0.0022 0.0156 0.0139
Giardia lamblia DINP protein human, muc B family 0.0022 0.0162 0.0091
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Trypanosoma brucei heat shock protein, putative 0.0053 0.0731 0.078
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0019 0.0101 0.0068
Brugia malayi intermediate filament protein 0.0032 0.0339 0.0499
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0261 0.0592
Brugia malayi nuclear receptor NHR-67 0.0017 0.0059 0.0005
Trypanosoma cruzi heat shock protein 90, putative 0.0045 0.0589 0.0595
Brugia malayi AF-10 protein 0.0022 0.0161 0.0185
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0042 0.0537 0.0536
Onchocerca volvulus 0.0035 0.04 0.062
Brugia malayi MH1 domain containing protein 0.0019 0.0101 0.0079
Schistosoma mansoni notch 0.002 0.0112 0.0076
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0027 0.0243 0.0395
Schistosoma mansoni kinase 0.0159 0.2702 0.3752
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0022 0.0156 0.0139
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0268 0.0484
Echinococcus granulosus citrate lyase subunit beta protein 0.0057 0.0811 0.0781
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0243 0.0492
Echinococcus granulosus heat shock protein 90 0.0053 0.0731 0.07
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0036 0.0408 0.062
Trichomonas vaginalis conserved hypothetical protein 0.023 0.4028 0.7162
Schistosoma mansoni 6-phosphofructokinase 0.0128 0.2133 0.2944
Mycobacterium ulcerans pyruvate kinase 0.0079 0.1212 0.2763
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0408 0.0376
Schistosoma mansoni dehydrodolichyl diphosphate synthase (dedol-pp synthase) 0.0026 0.0225 0.0236
Loa Loa (eye worm) PHD-finger family protein 0.0068 0.1013 0.1193
Echinococcus granulosus X box binding protein 1 0.034 0.607 0.6057
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0038 0.0459 0.0476
Loa Loa (eye worm) hypothetical protein 0.0231 0.4034 0.4831
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Echinococcus multilocularis JmjC domain containing protein 4 0.0022 0.0156 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0243 0.015
Trypanosoma brucei Heat shock protein 83, putative 0.0053 0.0731 0.078
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0108 0.175 0.1918
Trypanosoma cruzi trypanothione reductase, putative 0.011 0.18 0.1952
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Onchocerca volvulus Slit protein homolog 0.002 0.0115 0.0101
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0289 0.0258
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0036 0.0408 0.062
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.0339 0.0382
Trypanosoma brucei heat shock protein, putative 0.0053 0.0731 0.078
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.0027 0.0246 0.0441
Loa Loa (eye worm) hypothetical protein 0.002 0.0115 0.0111
Toxoplasma gondii heat shock protein 75, putative 0.0035 0.0401 0.1003
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0057 0.0811 0.0843
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0017 0.0059 0.0026
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0022 0.0156 0.0109
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0115 0.0174
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0622 0.0997
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0027 0.0246 0.0214
Toxoplasma gondii ABC1 family protein 0.0035 0.04 0.1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0017 0.0059 0.0026
Leishmania major pyruvate kinase 0.0079 0.1212 0.1349
Loa Loa (eye worm) hypothetical protein 0.0322 0.5734 0.6878
Echinococcus multilocularis neurogenic locus protein delta 0.002 0.0112 0.0079
Toxoplasma gondii undecaprenyl diphosphate synthase 0.0026 0.0225 0.0487
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0162 0.0144
Echinococcus granulosus peroxidasin 0.0061 0.0879 0.0849
Brugia malayi Protein cec-1. 0.0027 0.0243 0.0329
Entamoeba histolytica heat shock protein 90, putative 0.0053 0.0731 0.1242
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0162 0.0147
Loa Loa (eye worm) acetyltransferase 0.0171 0.2928 0.35
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0017 0.0059 0.0005
Schistosoma mansoni smad 0.0019 0.0101 0.006
Schistosoma mansoni jumonji domain containing protein 0.0177 0.3041 0.4233
Echinococcus multilocularis heat shock protein 90 0.0045 0.0589 0.0558
Trichomonas vaginalis chromobox protein, putative 0.0163 0.2772 0.4835
Plasmodium vivax heterochromatin protein 1, putative 0.0027 0.0243 0.0492
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0038 0.0459 0.0568
Trypanosoma brucei heat shock protein, putative 0.0053 0.0731 0.078
Trypanosoma cruzi heat shock protein, putative 0.0035 0.0401 0.0384
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0162 0.0269
Plasmodium vivax glutathione reductase, putative 0.011 0.18 0.4405
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0243 0.015
Brugia malayi MH2 domain containing protein 0.0019 0.0101 0.0079
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0108 0.175 0.208
Schistosoma mansoni notch 0.002 0.0112 0.0076
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0243 0.015
Trichomonas vaginalis esterase, putative 0.0035 0.04 0.0442
Echinococcus multilocularis thyroid hormone receptor alpha 0.0036 0.0408 0.0376
Schistosoma mansoni zinc finger protein 0.0017 0.0059 0.0001
Plasmodium vivax dehydrodolichyl diphosphate synthetase, putative 0.0026 0.0225 0.0448
Brugia malayi Amidase family protein 0.0027 0.0246 0.0335
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0268 0.0338
Loa Loa (eye worm) hypothetical protein 0.0035 0.04 0.0455
Loa Loa (eye worm) hypothetical protein 0.0021 0.0136 0.0137
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0045 0.0589 0.0558
Trypanosoma cruzi pyruvate kinase 2, putative 0.0079 0.1212 0.1292
Loa Loa (eye worm) thioredoxin reductase 0.011 0.18 0.2141
Echinococcus granulosus neurogenic locus notch protein 0.002 0.0112 0.0079
Echinococcus multilocularis pyruvate kinase 0.004 0.0499 0.0467
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0027 0.0243 0.0261
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0162 0.0186
Brugia malayi Nuclear hormone receptor E75 0.0017 0.0059 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0162 0.0144
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0028 0.0261 0.0975
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0243 0.015
Brugia malayi Associated with TFs and helicases family protein 0.0027 0.0243 0.0329
Mycobacterium ulcerans undecaprenyl pyrophosphate synthase 0.0026 0.0225 0.0227
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Brugia malayi glutathione reductase 0.011 0.18 0.3072
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0162 0.0129
Loa Loa (eye worm) hypothetical protein 0.0098 0.1572 0.1866
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0038 0.0459 0.0511
Brugia malayi glucose-6-phosphate dehydrogenase 0.0108 0.175 0.2983
Brugia malayi M-phase phosphoprotein, mpp8 0.0027 0.0243 0.0329
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Echinococcus granulosus pyruvate kinase 0.0079 0.1212 0.1182
Mycobacterium ulcerans amidase 0.0027 0.0246 0.0283
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0108 0.175 0.24
Loa Loa (eye worm) hypothetical protein 0.0028 0.0268 0.0296
Trypanosoma cruzi C-14 sterol reductase, putative 0.0047 0.0629 0.064
Trichomonas vaginalis CAMK family protein kinase 0.0313 0.5561 1
Echinococcus multilocularis citrate lyase subunit beta protein 0.0057 0.0811 0.0781
Loa Loa (eye worm) hypothetical protein 0.0072 0.1077 0.127
Entamoeba histolytica hypothetical protein 0.0042 0.052 0.0858
Schistosoma mansoni hypothetical protein 0.0018 0.0086 0.0039
Chlamydia trachomatis isoprenyl transferase 0.0026 0.0225 0.0548
Brugia malayi EGF-like domain containing protein 0.002 0.0112 0.0099
Brugia malayi Pre-SET motif family protein 0.0035 0.0403 0.0611
Trypanosoma cruzi Heat shock protein 83, putative 0.0053 0.0731 0.0754
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0036 0.0408 0.062
Entamoeba histolytica recQ family helicase, putative 0.0042 0.0537 0.0889
Brugia malayi nuclear receptor RXR 0.0017 0.0059 0.0005
Brugia malayi EGF-like domain containing protein 0.002 0.0112 0.0099
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0036 0.0408 0.0465
Echinococcus multilocularis heat shock protein 90 0.0053 0.0731 0.07
Loa Loa (eye worm) CHromoDomain protein family member 0.0027 0.0243 0.0265
Brugia malayi MH2 domain containing protein 0.0279 0.4931 0.8585
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0065 0.0051
Brugia malayi Pyruvate kinase, muscle isozyme 0.0079 0.1212 0.2035
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.04 0.0753
Onchocerca volvulus Pyruvate kinase homolog 0.0079 0.1212 0.2095
Onchocerca volvulus 0.002 0.0112 0.0096
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0537 0.0694
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0036 0.0408 0.0465
Echinococcus granulosus neuropeptide receptor A26 0.0552 1 1
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0108 0.175 0.1722
Schistosoma mansoni notch 0.002 0.0112 0.0076
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0027 0.0246 0.0502
Schistosoma mansoni protein phosphatase 2C 0.0022 0.0156 0.0139
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0086 0.0053
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.005 0.0671 0.0747
Brugia malayi hypothetical protein 0.0042 0.052 0.0817
Loa Loa (eye worm) hypothetical protein 0.0022 0.0156 0.0161
Entamoeba histolytica pyruvate kinase, putative 0.0055 0.0769 0.131
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.04 0.0442
Echinococcus granulosus nuclear receptor nhr 48 0.0017 0.0059 0.0026
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0128 0.2133 0.2324
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0265
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0162 0.0066
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0036 0.0408 0.0496
Giardia lamblia PHD finger protein 15 0.0068 0.1013 0.1654
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0162 0.0144
Echinococcus multilocularis jumonji domain containing 1A 0.0022 0.0156 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0162 0.0144
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0087 0.0083
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0392 0.0976
Schistosoma mansoni pyruvate kinase 0.0079 0.1212 0.1637
Brugia malayi Animal haem peroxidase family protein 0.0061 0.0876 0.1445
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0038 0.0459 0.1036
Loa Loa (eye worm) heat shock protein 90 0.0053 0.0731 0.0854
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0027 0.0246 0.0214
Onchocerca volvulus 0.0032 0.0339 0.0509
Schistosoma mansoni nuclear receptor 0.0017 0.0059 0.0001
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0022 0.0161 0.0143
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0243 0.015
Leishmania major monoglyceride lipase, putative 0.023 0.4028 0.4484
Mycobacterium ulcerans peptide amidase, GatA 0.0027 0.0246 0.0283
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0038 0.0459 0.2
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0108 0.175 0.4145
Echinococcus multilocularis phd:f box containing protein 0.0022 0.0156 0.0123
Giardia lamblia Undecaprenyl pyrophosphate synthase 0.0026 0.0225 0.0207
Schistosoma mansoni hypothetical protein 0.0022 0.0161 0.0146
Echinococcus multilocularis peroxidasin 0.0061 0.0879 0.0849
Plasmodium vivax endoplasmin, putative 0.0053 0.0731 0.172
Echinococcus multilocularis smad 0.0019 0.0101 0.0068
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Loa Loa (eye worm) Smad1 0.0019 0.0101 0.0094
Schistosoma mansoni hypothetical protein 0.0027 0.0243 0.0261
Schistosoma mansoni hypothetical protein 0.002 0.0112 0.0076
Loa Loa (eye worm) hypothetical protein 0.0036 0.0408 0.0465
Trypanosoma cruzi polo-like protein kinase, putative 0.0313 0.5561 0.6165
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0027 0.0243 0.0539
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Echinococcus multilocularis chromobox protein 1 0.0163 0.2772 0.2748
Schistosoma mansoni chromobox protein 0.0163 0.2772 0.3852
Trypanosoma cruzi heat shock protein 85, putative 0.0053 0.0731 0.0754
Mycobacterium ulcerans lipoprotein LpqF 0.0074 0.1115 0.2515
Entamoeba histolytica heat shock protein 90, putative 0.0053 0.0731 0.1242
Echinococcus multilocularis 6 phosphofructokinase 0.0128 0.2133 0.2107
Schistosoma mansoni notch 0.002 0.0112 0.0076
Schistosoma mansoni DNA helicase recq1 0.0033 0.0358 0.0424
Brugia malayi hypothetical protein 0.0019 0.0097 0.0071
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Schistosoma mansoni hypothetical protein 0.0018 0.0086 0.0039
Schistosoma mansoni thyroid hormone receptor 0.0036 0.0408 0.0496
Loa Loa (eye worm) hypothetical protein 0.0035 0.04 0.0455
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0153 0.2597 0.6321
Brugia malayi Calcium binding EGF domain containing protein 0.002 0.0112 0.0099
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.04 0.0753
Trypanosoma cruzi cis-prenyltransferase, putative 0.0026 0.0225 0.0186
Echinococcus granulosus Smad4 0.0019 0.0101 0.0068
Toxoplasma gondii NADPH-glutathione reductase 0.0038 0.0459 0.1172
Trypanosoma brucei heat shock protein, putative 0.0053 0.0731 0.078
Loa Loa (eye worm) pyruvate kinase 0.0079 0.1212 0.1432
Brugia malayi Muscle positioning protein 4 0.002 0.0112 0.0099
Echinococcus multilocularis X box binding protein 1 0.034 0.607 0.6057
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0027 0.0243 0.0395
Trichomonas vaginalis CAMK family protein kinase 0.0313 0.5561 1
Onchocerca volvulus 0.0061 0.0876 0.1485
Brugia malayi hypothetical protein 0.0029 0.0289 0.041
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0128 0.2133 0.2346
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.007 0.1046 0.2432
Mycobacterium ulcerans amidase 0.0027 0.0246 0.0283
Loa Loa (eye worm) pyruvate kinase-PB 0.0055 0.0769 0.0899
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Loa Loa (eye worm) MH2 domain-containing protein 0.0279 0.4931 0.5911
Schistosoma mansoni septate junction protein 0.002 0.0112 0.0076
Entamoeba histolytica phosphofructokinase, putative 0.0128 0.2133 0.3784
Schistosoma mansoni intermediate filament proteins 0.0032 0.0339 0.0399
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0086 0.0077
Trypanosoma cruzi amidase, putative 0.0027 0.0246 0.0211
Brugia malayi nuclear hormone receptor 0.0017 0.0059 0.0005
Onchocerca volvulus Peroxidase homolog 0.0061 0.0876 0.1485
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0629 0.064
Brugia malayi nuclear receptor NHR-88 0.0017 0.0059 0.0005
Brugia malayi Hsp90 protein 0.0035 0.0401 0.0608
Schistosoma mansoni peroxidasin 0.0061 0.0879 0.1165
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0392 0.0868
Schistosoma mansoni RAR-like nuclear receptor 0.0036 0.0408 0.0496
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0265
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0074 0.1115 0.2205
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.005 0.0683 0.0965
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0162 0.0144
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0162 0.0066
Trichomonas vaginalis CAMK family protein kinase 0.0313 0.5561 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0038 0.0459 0.0636
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0252 0.443 0.8939
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0261 0.0441
Loa Loa (eye worm) hypothetical protein 0.0223 0.3883 0.4649
Leishmania major hypothetical protein, conserved 0.0029 0.0289 0.0321
Schistosoma mansoni nuclear hormone receptor 0.0036 0.0408 0.0496
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0036 0.0411 0.0395
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Echinococcus granulosus dehydrodolichyl diphosphate synthase 0.0026 0.0225 0.0192
Entamoeba histolytica hypothetical protein 0.0042 0.052 0.0858
Loa Loa (eye worm) hypothetical protein 0.0019 0.0097 0.0089
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.052 0.0488
Entamoeba histolytica hypothetical protein 0.0042 0.052 0.0858
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0054 0.0747 0.1758
Mycobacterium ulcerans beta-lactamase 0.0035 0.04 0.0678
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0038 0.0459 0.0511
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0162 0.0116
Echinococcus multilocularis geminin 0.0396 0.7104 0.7094
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0097 0.0054
Echinococcus multilocularis muscleblind protein 1 0.0322 0.5734 0.5719
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0036 0.0408 0.0496
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0033 0.0358 0.0531
Brugia malayi beta-lactamase family protein 0.0035 0.04 0.0606
Echinococcus granulosus Chromo domain 0.0027 0.0243 0.021
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0022 0.0161 0.0143
Trichomonas vaginalis CAMK family protein kinase 0.0313 0.5561 1
Loa Loa (eye worm) phosphofructokinase 0.0128 0.2133 0.2542
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0038 0.0459 0.0427
Loa Loa (eye worm) hypothetical protein 0.0036 0.0408 0.0465
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Brugia malayi Steroid receptor seven-up type 2 0.0036 0.0408 0.062
Schistosoma mansoni blooms syndrome DNA helicase 0.0063 0.0914 0.1214
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.04 0.0383
Brugia malayi Thioredoxin reductase 0.011 0.18 0.3072
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0059 0.0001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0403 0.0371
Trypanosoma brucei heat shock protein, putative 0.0053 0.0731 0.078
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0057 0.0811 0.1734
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0392 0.0868
Onchocerca volvulus 0.0047 0.0622 0.1023
Brugia malayi steroid hormone receptor 0.0036 0.0408 0.062
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Entamoeba histolytica phosphofructokinase, putative 0.0128 0.2133 0.3784
Trypanosoma cruzi C-14 sterol reductase, putative 0.0047 0.0629 0.064
Giardia lamblia Pyruvate kinase 0.004 0.0499 0.071
Schistosoma mansoni notch 0.002 0.0112 0.0076
Loa Loa (eye worm) hypothetical protein 0.0021 0.0136 0.0137
Trichomonas vaginalis chromobox protein, putative 0.0098 0.1572 0.2612
Toxoplasma gondii Hsp90 domain-containing protein 0.0201 0.3476 1
Trypanosoma brucei trypanothione reductase 0.011 0.18 0.1974
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0162 0.0144
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.04 0.0753
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0403 0.0489
Trypanosoma cruzi hypothetical protein, conserved 0.0497 0.8983 1
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0087 0.0054
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0261 0.0254
Onchocerca volvulus Neurogenic locus notch homolog 0.002 0.0112 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0036 0.0408 0.062
Echinococcus granulosus chromobox protein 1 0.0163 0.2772 0.2748
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0028 0.0268 0.0484
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0022 0.0156 0.0286
Schistosoma mansoni chromobox protein 0.0027 0.0243 0.0261
Echinococcus multilocularis Chromo domain 0.0027 0.0243 0.021
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0117 0.1928 0.3332
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.04 0.0485
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0038 0.0459 0.0829
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.0027 0.0246 0.0405
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0033 0.0358 0.0325
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.04 0.0753
Entamoeba histolytica serine/threonine protein kinase, putative 0.0313 0.5561 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0162 0.0168
Brugia malayi heat shock protein 90 0.0053 0.0731 0.1189
Toxoplasma gondii heat shock protein 90, putative 0.0053 0.0731 0.1969
Trypanosoma brucei beta lactamase 0.0074 0.1115 0.1209
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0117 0.1928 0.3271
Loa Loa (eye worm) hypothetical protein 0.0019 0.0097 0.0089
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0057 0.0811 0.0843
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0038 0.0459 0.0511
Brugia malayi EGF-like domain containing protein 0.002 0.0112 0.0099
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.04 0.0753
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0162 0.0144
Brugia malayi jmjC domain containing protein 0.0022 0.0156 0.0176
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Schistosoma mansoni endoplasmin 0.0053 0.0731 0.0955
Mycobacterium ulcerans lipase LipD 0.0035 0.04 0.0678
Mycobacterium ulcerans Z-decaprenyl diphosphate synthase 0.0026 0.0225 0.0227
Echinococcus granulosus JmjC domain containing protein 4 0.0022 0.0156 0.0123
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Leishmania major hypothetical protein, conserved 0.0027 0.0246 0.0274
Plasmodium vivax thioredoxin reductase, putative 0.011 0.18 0.4405
Plasmodium vivax hypothetical protein, conserved 0.0035 0.04 0.0888
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0268 0.0484
Mycobacterium leprae PROBABLE AMIDASE AMIC (AMINOHYDROLASE) 0.0027 0.0246 0.0441
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0268 0.0298
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0087 0.0054
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0268 0.0338
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0036 0.0408 0.0465
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0036 0.0408 0.0465
Trichomonas vaginalis chromobox protein, putative 0.0163 0.2772 0.4835
Echinococcus multilocularis protein jagged 2 0.002 0.0112 0.0079
Schistosoma mansoni Smad4 0.0019 0.0101 0.006
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0108 0.175 0.1948
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.04 0.0368
Schistosoma mansoni hypothetical protein 0.0068 0.1013 0.1355
Echinococcus multilocularis muscleblind protein 0.0322 0.5734 0.5719
Schistosoma mansoni endoplasmin 0.0053 0.0731 0.0955
Loa Loa (eye worm) amidase 0.0027 0.0246 0.027
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0087 0.0054
Brugia malayi tailless protein 0.0017 0.0059 0.0005
Brugia malayi Valyl-tRNA synthetase 0.0027 0.0243 0.0329
Brugia malayi Calcium binding EGF domain containing protein 0.002 0.0112 0.0099
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0036 0.0408 0.0634
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0268 0.0298
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0108 0.175 0.1895
Brugia malayi hypothetical protein 0.0017 0.0059 0.0005
Loa Loa (eye worm) hypothetical protein 0.0058 0.0818 0.0958
Trichomonas vaginalis pyruvate kinase, putative 0.0079 0.1212 0.1945
Schistosoma mansoni dehydrodolichyl diphosphate synthase (dedol-pp synthase) 0.0026 0.0225 0.0236
Echinococcus granulosus fatty acid amide hydrolase 1 0.0027 0.0246 0.0214
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0459 0.0449
Brugia malayi jmjC domain containing protein 0.0022 0.0156 0.0176
Loa Loa (eye worm) hypothetical protein 0.0035 0.04 0.0455
Onchocerca volvulus 0.0032 0.0339 0.0509
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.023 0.4028 0.7162
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0948 0.1456
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0243 0.015
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0392 0.0426
Loa Loa (eye worm) pyruvate kinase 0.0017 0.0056 0.0041
Echinococcus granulosus bloom syndrome protein 0.0079 0.1225 0.1196
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0038 0.0459 0.0449
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0059 0.0026
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0028 0.0261 0.032
Brugia malayi Cadherin domain containing protein 0.002 0.0112 0.0099
Brugia malayi Calcium binding EGF domain containing protein 0.002 0.0112 0.0099
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0065 0.0015
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0017 0.0059 0.0026
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.04 0.0442
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0128 0.2133 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0818 0.1342
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0101 0.0094
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Onchocerca volvulus Peroxidasin homolog 0.0061 0.0879 0.149
Plasmodium falciparum phd finger protein, putative 0.0068 0.1013 0.2351
Trypanosoma brucei polo-like protein kinase 0.0313 0.5561 0.6176
Loa Loa (eye worm) hypothetical protein 0.0028 0.0268 0.0296
Plasmodium falciparum lysophospholipase, putative 0.023 0.4028 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0459 0.0449
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0243 0.015
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0289 0.0285
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.052 0.0655
Brugia malayi amidase 0.0223 0.3883 0.674
Onchocerca volvulus Protein ultraspiracle homolog 0.0036 0.0408 0.0634
Brugia malayi Nuclear hormone receptor-like 1 0.0036 0.0408 0.062
Loa Loa (eye worm) hypothetical protein 0.0091 0.1443 0.1711
Trichomonas vaginalis chromobox protein, putative 0.0027 0.0243 0.015
Plasmodium vivax heat shock protein 86, putative 0.0053 0.0731 0.172
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0392 0.0976
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.04 0.0368
Onchocerca volvulus 0.0061 0.0876 0.1485
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0243 0.015
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0027 0.0243 0.0329
Echinococcus multilocularis nuclear receptor nhr 48 0.0017 0.0059 0.0026
Brugia malayi jmjC domain containing protein 0.0223 0.3893 0.6758
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0459 0.0449
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0087 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0036 0.0408 0.062
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0289 0.0674
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0072 0.108 0.105
Brugia malayi EGF-like domain containing protein 0.002 0.0112 0.0099
Mycobacterium ulcerans aldehyde dehydrogenase 0.0072 0.108 0.2425
Schistosoma mansoni hypothetical protein 0.0018 0.0086 0.0039
Brugia malayi nuclear hormone receptor family member nhr-6 0.0017 0.0059 0.0005
Echinococcus granulosus pyruvate kinase 0.004 0.0499 0.0467
Mycobacterium ulcerans hypothetical protein 0.0035 0.04 0.0678
Echinococcus granulosus TGF beta signal transducer SmadC 0.0019 0.0101 0.0068
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0268 0.0298
Brugia malayi Nuclear hormone receptor E75 0.0017 0.0059 0.0005
Plasmodium vivax SET domain protein, putative 0.0035 0.0403 0.0894
Toxoplasma gondii EGF family domain-containing protein 0.002 0.0112 0.0158
Brugia malayi chromobox protein homolog 3 0.0091 0.1443 0.2443
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0162 0.0144
Loa Loa (eye worm) hypothetical protein 0.0036 0.0408 0.0465
Entamoeba histolytica phosphofructokinase, putative 0.0128 0.2133 0.3784
Mycobacterium ulcerans hypothetical protein 0.0028 0.0268 0.0338
Echinococcus granulosus ecdysone induced protein 78C 0.0036 0.0408 0.0376
Trypanosoma brucei heat shock protein, putative 0.0053 0.0731 0.078
Mycobacterium leprae conserved hypothetical protein 0.0035 0.04 0.0753
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0268 0.0338
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0392 0.0426
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0036 0.0408 0.0465
Trypanosoma cruzi heat shock protein 90, putative 0.0053 0.0731 0.0754
Trypanosoma brucei hypothetical protein, conserved 0.0497 0.8983 1
Echinococcus multilocularis neuropeptide receptor A26 0.0552 1 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.011 0.18 0.3597
Loa Loa (eye worm) hypothetical protein 0.0264 0.4657 0.5581
Trichomonas vaginalis DNA helicase recq1, putative 0.0079 0.1225 0.1969
Trichomonas vaginalis phosphofructokinase, putative 0.0128 0.2133 0.3651
Onchocerca volvulus 0.0035 0.04 0.062
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.052 0.0488
Echinococcus granulosus pyruvate kinase 0.0079 0.1212 0.1182
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0019 0.0097 0.0064
Leishmania major hypothetical protein, conserved 0.0022 0.0156 0.0174
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0059 0.0026
Echinococcus granulosus fatty acid amide hydrolase 1 0.0223 0.3883 0.3863
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.023 0.4028 0.7221
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0268 0.0401
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0072 0.108 0.1202
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0161 0.0288
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0059 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0162 0.0144
Schistosoma mansoni heat shock protein 0.0053 0.0731 0.0955
Entamoeba histolytica hypothetical protein 0.0027 0.0243 0.0356
Onchocerca volvulus Putative cubilin 0.002 0.0112 0.0096
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.04 0.0753
Entamoeba histolytica acetyltransferase, GNAT family 0.0046 0.0605 0.1013
Schistosoma mansoni heat shock protein 0.0053 0.0731 0.0955
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0117 0.1928 0.3271
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0027 0.0246 0.0283
Plasmodium falciparum heterochromatin protein 1 0.0027 0.0243 0.0395
Mycobacterium ulcerans 6-phosphofructokinase 0.0128 0.2133 0.513
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.2625 0.4563
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0037 0.0442 0.0838
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Echinococcus multilocularis fibropellin Ia 0.002 0.0112 0.0079
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Echinococcus multilocularis pyruvate kinase 0.0079 0.1212 0.1182
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.0185 0.0228
Trypanosoma brucei heat shock protein, putative 0.0053 0.0731 0.078
Loa Loa (eye worm) jmjC domain-containing protein 0.0022 0.0156 0.0161
Plasmodium falciparum glutathione reductase 0.011 0.18 0.4348
Brugia malayi orphan nuclear receptor NR2E1 0.0017 0.0059 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0243 0.015
Schistosoma mansoni fatty-acid amide hydrolase 0.0027 0.0246 0.0267
Echinococcus multilocularis neurogenic locus notch protein 0.002 0.0112 0.0079
Entamoeba histolytica hypothetical protein 0.0027 0.0243 0.0356
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0036 0.0408 0.062
Onchocerca volvulus Serine\/threonine kinase homolog 0.0313 0.5561 1
Echinococcus granulosus heat shock protein 90 0.0045 0.0589 0.0558
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0087 0.0083
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0017 0.0059 0.0026
Trichomonas vaginalis undecaprenyl diphosphate synthase, putative 0.0026 0.0225 0.0117
Loa Loa (eye worm) hypothetical protein 0.0035 0.04 0.0455
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0268 0.0338
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0223 0.3883 0.3863
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0392 0.0426
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0392 0.0426
Loa Loa (eye worm) amidase 0.0027 0.0246 0.027
Echinococcus multilocularis L aminoadipate semialdehyde 0.0098 0.1572 0.1544
Echinococcus granulosus histone acetyltransferase KAT2B 0.005 0.0683 0.0652
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0246 0.4315 0.5169
Echinococcus granulosus muscleblind protein 0.0322 0.5734 0.5719
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0038 0.0459 0.1036
Trichomonas vaginalis heat shock protein, putative 0.005 0.0671 0.0943
Trichomonas vaginalis heat shock protein, putative 0.0038 0.0462 0.0555
Echinococcus granulosus FTZ F1 alpha 0.0036 0.0408 0.0376
Brugia malayi isocitrate dehydrogenase 0.0018 0.0087 0.0054
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0162 0.0116
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.028 0.4953 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.005 0.0683 0.1828
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.0027 0.0246 0.0441
Brugia malayi Blistered cuticle protein 3 0.0061 0.0876 0.1445
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Leishmania major ATP-dependent phosphofructokinase 0.0128 0.2133 0.2374
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0036 0.0408 0.0376
Brugia malayi ecdysteroid receptor 0.0036 0.0408 0.062
Treponema pallidum heat shock protein 90 0.005 0.0671 0.2952
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0033 0.0358 0.0531
Echinococcus multilocularis peregrin 0.0072 0.1091 0.1062
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0038 0.0459 0.5249
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0038 0.0459 0.0476
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0289 0.0512
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0027 0.0243 0.0261
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0223 0.3893 0.3873
Mycobacterium ulcerans hypothetical protein 0.023 0.4028 1
Giardia lamblia Heat shock protein HSP 90-alpha 0.0053 0.0731 0.1136
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0243 0.015
Schistosoma mansoni cell polarity protein 0.002 0.0112 0.0076
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0265
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.3917 0.7897
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0036 0.0408 0.0465
Schistosoma mansoni laminin gamma-3 chain 0.002 0.0112 0.0076
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0033 0.0358 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.1443 0.2373
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0028 0.0261 0.0806
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0162 0.0209
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0086 0.0053
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.04 0.0383
Toxoplasma gondii PHD-finger domain-containing protein 0.0068 0.1013 0.2794
Echinococcus multilocularis protein jagged 1 0.002 0.0112 0.0079
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0079 0.1212 0.2401
Schistosoma mansoni amidase 0.0223 0.3883 0.5428
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0403 0.0489
Trichomonas vaginalis Heterochromatin protein, putative 0.0027 0.0243 0.015
Trypanosoma brucei heat shock protein, putative 0.0053 0.0731 0.078
Schistosoma mansoni 6-phosphofructokinase 0.0128 0.2133 0.2944
Plasmodium vivax pyruvate kinase 2, putative 0.004 0.0499 0.1136
Trichomonas vaginalis phosphofructokinase, putative 0.0128 0.2133 0.3651
Schistosoma mansoni survival motor neuron protein 0.0047 0.0622 0.08
Brugia malayi Animal haem peroxidase family protein 0.0061 0.0876 0.1445
Echinococcus multilocularis chromobox protein 1 0.0163 0.2772 0.2748
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.005 0.0683 0.1828
Schistosoma mansoni heat shock protein 0.0035 0.0401 0.0486
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0036 0.0408 0.0465
Mycobacterium tuberculosis Conserved protein 0.0057 0.0811 0.1588
Brugia malayi Peroxidasin 0.0061 0.0879 0.1449
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.005 0.0671 0.1303
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0038 0.0459 0.0476
Plasmodium falciparum thioredoxin reductase 0.011 0.18 0.4348
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.023 0.4028 0.8122
Loa Loa (eye worm) hypothetical protein 0.0061 0.0879 0.1032
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.0161 0.0189
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0479 0.0745
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0162 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0036 0.0408 0.062
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.007 0.1055 0.2916
Echinococcus multilocularis lamin dm0 0.0032 0.0339 0.0307
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0171 0.2928 0.4073
Loa Loa (eye worm) 6-phosphofructokinase 0.0128 0.2133 0.2542
Loa Loa (eye worm) jmjC domain-containing protein 0.0022 0.0156 0.0161
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0022 0.0156 0.0286
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.023 0.4028 0.7162
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0162 0.0116
Mycobacterium ulcerans lysophospholipase 0.023 0.4028 1
Trypanosoma brucei monoglyceride lipase, putative 0.023 0.4028 0.4464
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0027 0.0243 0.0539
Giardia lamblia Grp94/Hsp90 0.005 0.0671 0.1025
Loa Loa (eye worm) hypothetical protein 0.0035 0.04 0.0455
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0036 0.0408 0.062
Mycobacterium ulcerans amidase 0.0027 0.0246 0.0283
Echinococcus granulosus histone acetyltransferase KAT2B 0.0166 0.2839 0.2815
Plasmodium falciparum heat shock protein 90, putative 0.0031 0.0319 0.059
Brugia malayi Bromodomain containing protein 0.0072 0.1091 0.1823
Echinococcus granulosus protein jagged 2 0.002 0.0112 0.0079
Entamoeba histolytica hypothetical protein 0.0028 0.0261 0.0388
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0459 0.0449
Brugia malayi hypothetical protein 0.0264 0.4657 0.8104
Loa Loa (eye worm) hypothetical protein 0.002 0.0112 0.0108
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.002 0.0112 0.0099
Onchocerca volvulus 0.028 0.4946 0.8882
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0057 0.0811 0.0903
Schistosoma mansoni aldehyde dehydrogenase 0.0072 0.108 0.145
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.007 0.1055 0.2361
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.04 0.0678
Giardia lamblia Histone acetyltransferase GCN5 0.0046 0.0605 0.0904
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0265
Loa Loa (eye worm) hypothetical protein 0.0018 0.0086 0.0077
Brugia malayi hypothetical protein 0.0061 0.0876 0.1445
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0038 0.0459 0.0872
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0392 0.0626
Schistosoma mansoni smad1 5 8 and 0.0019 0.0101 0.006
Echinococcus multilocularis GPCR, family 2 0.0018 0.0086 0.0053
Brugia malayi Undecaprenyl diphosphate synthase family protein 0.0026 0.0225 0.0297
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0115 0.0174
Brugia malayi jmjC domain containing protein 0.0022 0.0156 0.0176
Loa Loa (eye worm) hypothetical protein 0.0019 0.0097 0.0089
Brugia malayi nuclear receptor NHR-88 0.0036 0.0408 0.062
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.04 0.0442
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0379 0.0347
Loa Loa (eye worm) hypothetical protein 0.0022 0.0156 0.0161
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0036 0.0408 0.0376
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0115 0.0174
Schistosoma mansoni steroid hormone receptor ad4bp 0.0036 0.0408 0.0496
Trichomonas vaginalis mercuric reductase, putative 0.0038 0.0459 0.055
Echinococcus multilocularis fat cadherin tumor suppressor 0.002 0.0112 0.0079
Echinococcus multilocularis notch 0.002 0.0112 0.0079
Onchocerca volvulus 0.0027 0.0243 0.0333
Brugia malayi jmjC domain containing protein 0.0082 0.128 0.2155
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0019 0.0101 0.006
Onchocerca volvulus Neurogenic locus notch protein homolog 0.002 0.0112 0.0096
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0243 0.015
Loa Loa (eye worm) blistered cuticle protein 3 0.0061 0.0876 0.1028
Loa Loa (eye worm) hypothetical protein 0.0079 0.1212 0.1432
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.5561 0.781
Echinococcus granulosus Chromobox protein 3 0.0027 0.0243 0.021
Echinococcus multilocularis chromobox protein 2 0.0027 0.0243 0.021
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.2625 0.4563
Echinococcus multilocularis neural cadherin 0.002 0.0112 0.0079
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0392 0.0513
Onchocerca volvulus Alhambra homolog 0.0068 0.1013 0.1734
Trypanosoma cruzi hypothetical protein, conserved 0.0497 0.8983 1
Toxoplasma gondii pyruvate kinase PyK1 0.0079 0.1212 0.3375
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0243 0.015
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0136 0.0126
Trypanosoma cruzi heat shock protein 85, putative 0.0053 0.0731 0.0754
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0027 0.0243 0.021
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0038 0.0459 0.0449
Loa Loa (eye worm) hypothetical protein 0.0117 0.1918 0.2282
Onchocerca volvulus 0.0036 0.0408 0.0634
Trichomonas vaginalis chromobox protein, putative 0.0098 0.1572 0.2612
Trichomonas vaginalis CAMK family protein kinase 0.0313 0.5561 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0017 0.0059 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.04 0.041
Trichomonas vaginalis pyruvate kinase, putative 0.0079 0.1212 0.1945
Giardia lamblia Pyruvate kinase 0.0079 0.1212 0.2018
Loa Loa (eye worm) jmjC domain-containing protein 0.0022 0.0156 0.0161
Echinococcus granulosus protein jagged 2 0.002 0.0112 0.0079
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0033 0.0358 0.0875
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0024 0.0191 0.0237
Leishmania major heat shock protein 83-1 0.0053 0.0731 0.0814
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0392 0.1585
Schistosoma mansoni hypothetical protein 0.002 0.0112 0.0076
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0313 0.5561 0.619
Mycobacterium ulcerans amidase 0.0027 0.0246 0.0283
Trypanosoma brucei heat shock protein 90, putative 0.0053 0.0731 0.078
Onchocerca volvulus 0.002 0.0112 0.0096
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0162 0.0168
Trypanosoma brucei pyruvate kinase 1, putative 0.0079 0.1212 0.1317
Brugia malayi EGF-like domain containing protein 0.002 0.0112 0.0099
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.005 0.0671 1
Onchocerca volvulus 0.002 0.0112 0.0096
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0629 0.064
Echinococcus granulosus neurogenic locus protein delta 0.002 0.0112 0.0079
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0036 0.0408 0.062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0243 0.015
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0087 0.006
Loa Loa (eye worm) hypothetical protein 0.0061 0.0876 0.1028
Brugia malayi 6-phosphofructokinase 0.0128 0.2133 0.3658
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0408 0.0376
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0162 0.0144
Schistosoma mansoni fatty-acid amide hydrolase 0.0223 0.3883 0.5428
Loa Loa (eye worm) endoplasmin 0.0053 0.0731 0.0854
Brugia malayi acetyltransferase, GNAT family protein 0.0171 0.2928 0.5059
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0019 0.0097 0.0054
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0028 0.0268 0.0338
Loa Loa (eye worm) animal heme peroxidase 0.0061 0.0876 0.1028
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.04 0.0678
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0136 0.0225
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.005 0.0671 0.1303
Trichomonas vaginalis phosphofructokinase, putative 0.0128 0.2133 0.3651
Wolbachia endosymbiont of Brugia malayi aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0027 0.0246 0.0484
Schistosoma mansoni chromobox protein 0.0163 0.2772 0.3852
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0162 0.0144
Brugia malayi beta-lactamase family protein 0.0035 0.04 0.0606
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0098 0.1572 0.267
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0033 0.0358 0.0325
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0087 0.0101
Loa Loa (eye worm) hypothetical protein 0.0017 0.0059 0.0044
Onchocerca volvulus 0.0027 0.0243 0.0333
Trypanosoma brucei heat shock protein 90, putative 0.0053 0.0731 0.078
Leishmania major pyruvate kinase 0.0079 0.1212 0.1349
Brugia malayi Animal haem peroxidase family protein 0.0061 0.0876 0.1445
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0243 0.0356
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0162 0.0144
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0261 0.0538
Trypanosoma brucei pyruvate kinase 1 0.0079 0.1212 0.1317
Loa Loa (eye worm) hypothetical protein 0.0029 0.0289 0.0321
Echinococcus granulosus dna polymerase kappa 0.0022 0.0162 0.0129

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.8 uM Inhibition of Streptococcus pneumoniae UPPS ChEMBL. 18295483
IC50 (binding) = 0.8 uM Inhibition of Streptococcus pneumoniae UPPS ChEMBL. 18295483
IC50 (binding) > 50 uM Inhibition of human FPPS ChEMBL. 18295483
IC50 (binding) > 50 uM Inhibition of human FPPS ChEMBL. 18295483
MIC (functional) = 4 ug ml-1 Antibacterial activity against Staphylococcus aureus by microdilution broth method ChEMBL. 18295483
MIC (functional) = 4 ug ml-1 Antibacterial activity against Streptococcus pneumoniae by microdilution broth method ChEMBL. 18295483
MIC (functional) = 8 ug ml-1 Antibacterial activity against Enterococcus faecalis by microdilution broth method ChEMBL. 18295483
pKa = 3 Dissociation constant, pKa of the compound ChEMBL. 18295483

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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