TDR Targets

Basic information

Technical information

TDR Targets ID: 522956
Name: 3-hydroxy-2-(4-methoxyphenyl)chromen-4-one
MW: 268.264 | Formula: C16H12O4
H donors: 1 H acceptors: 2 LogP: 3.01 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccc(cc1)c1oc2ccccc2c(=O)c1O
InChi: 1S/C16H12O4/c1-19-11-8-6-10(7-9-11)16-15(18)14(17)12-4-2-3-5-13(12)20-16/h2-9,18H,1H3
InChiKey: IIBBFGMVMNZMGA-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

3-hydroxy-2-(4-methoxyphenyl)-1-benzopyran-4-one
3-hydroxy-2-(4-methoxyphenyl)chromone
3-hydroxy-2-(4-methoxyphenyl)-4-chromenone
6889-78-7
3-Hydroxy-4'-methoxyflavanone
Oprea1_311422
3-Hydroxy-2-(4-methoxy-phenyl)-chromen-4-one
BAS 00790253
4H-1-Benzopyran-4-one, 3-hydroxy-2-(4-methoxyphenyl)- (9CI)
AIDS-045982
AIDS045982
3-Hydroxy-4'-methoxyflavone
4H-1-Benzopyran-4-one, 3-hydroxy-2-(4-methoxyphenyl)-
NSC102030
NCGC00142582-01
NSC 102030
ZINC00057683
EU-0034899
A1034/0048426
Oprea1_769880

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Mus musculus	RAR-related orphan receptor gamma	Starlite/ChEMBL	No references
Homo sapiens	arachidonate 15-lipoxygenase, type B	Starlite/ChEMBL	No references
Homo sapiens	aldehyde dehydrogenase 1 family, member A1	Starlite/ChEMBL	No references
Homo sapiens	cytochrome P450, family 3, subfamily A, polypeptide 4	Starlite/ChEMBL	No references
Homo sapiens	lysine (K)-specific demethylase 4E	Starlite/ChEMBL	No references
Homo sapiens	hydroxysteroid (17-beta) dehydrogenase 10	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Cryptosporidium parvum	scully CG7113-PA, putative	Get druggable targets OG5_129031	All targets in OG5_129031
Mycobacterium ulcerans	aldehyde dehydrogenase	Get druggable targets OG5_126638	All targets in OG5_126638
Schistosoma japonicum	Aldehyde dehydrogenase X, mitochondrial precursor, putative	Get druggable targets OG5_126638	All targets in OG5_126638
Leishmania donovani	aldehyde dehydrogenase, mitochondrial precursor	Get druggable targets OG5_126638	All targets in OG5_126638
Brugia malayi	3-hydroxyacyl-CoA dehydrogenase type II	Get druggable targets OG5_129031	All targets in OG5_129031
Trypanosoma congolense	cytochrome P450, putative	Get druggable targets OG5_126554	All targets in OG5_126554
Candida albicans	cytochrome P450 556	Get druggable targets OG5_126554	All targets in OG5_126554
Candida albicans	aldehyde dehydrogenase	Get druggable targets OG5_126638	All targets in OG5_126638
Loa Loa (eye worm)	3-hydroxyacyl-CoA dehydrogenase type II	Get druggable targets OG5_129031	All targets in OG5_129031
Mycobacterium ulcerans	aldehyde dehydrogenase	Get druggable targets OG5_126638	All targets in OG5_126638
Schistosoma mansoni	lipoxygenase	Get druggable targets OG5_127482	All targets in OG5_127482
Schistosoma mansoni	lipoxygenase	Get druggable targets OG5_127482	All targets in OG5_127482
Brugia malayi	Cytochrome P450 family protein	Get druggable targets OG5_126554	All targets in OG5_126554
Trypanosoma cruzi	cytochrome P450, putative	Get druggable targets OG5_126554	All targets in OG5_126554
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	Get druggable targets OG5_126638	All targets in OG5_126638
Trypanosoma brucei gambiense	cytochrome P450, putative	Get druggable targets OG5_126554	All targets in OG5_126554
Loa Loa (eye worm)	cytochrome P450 family protein	Get druggable targets OG5_126554	All targets in OG5_126554
Schistosoma mansoni	3-hydroxyacyl-CoA dehydrogenase	Get druggable targets OG5_129031	All targets in OG5_129031
Leishmania donovani	cytochrome p450-like protein	Get druggable targets OG5_126554	All targets in OG5_126554
Leishmania major	3-oxoacyl-(acyl-carrier protein) reductase, putative	Get druggable targets OG5_129031	All targets in OG5_129031
Candida albicans	Mitochondrial aldehyde dehydrogenase	Get druggable targets OG5_126638	All targets in OG5_126638
Echinococcus granulosus	arachidonate 5 lipoxygenase	Get druggable targets OG5_127482	All targets in OG5_127482
Schistosoma japonicum	IPR001024,Lipoxygenase, LH2;IPR013819,Lipoxygenase, C-terminal,domain-containing	Get druggable targets OG5_127482	All targets in OG5_127482
Candida albicans	cytochrome P450 56	Get druggable targets OG5_126554	All targets in OG5_126554
Cryptosporidium hominis	scully CG7113-PA	Get druggable targets OG5_129031	All targets in OG5_129031
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	Get druggable targets OG5_126638	All targets in OG5_126638
Schistosoma japonicum	Aldehyde dehydrogenase, mitochondrial precursor, putative	Get druggable targets OG5_126638	All targets in OG5_126638
Leishmania braziliensis	aldehyde dehydrogenase, mitochondrial precursor	Get druggable targets OG5_126638	All targets in OG5_126638
Candida albicans	aldehyde dehydrogenase	Get druggable targets OG5_126638	All targets in OG5_126638
Loa Loa (eye worm)	cytochrome P450 family protein	Get druggable targets OG5_126554	All targets in OG5_126554
Trypanosoma cruzi	cytochrome P450, putative	Get druggable targets OG5_126554	All targets in OG5_126554
Leishmania braziliensis	3-oxoacyl-(acyl-carrier protein) reductase, putative	Get druggable targets OG5_129031	All targets in OG5_129031
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	Get druggable targets OG5_126638	All targets in OG5_126638
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126554	All targets in OG5_126554
Loa Loa (eye worm)	CYP4Cod1	Get druggable targets OG5_126554	All targets in OG5_126554
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	Get druggable targets OG5_129031	All targets in OG5_129031
Candida albicans	closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA	Get druggable targets OG5_126554	All targets in OG5_126554
Leishmania infantum	3-oxoacyl-(acyl-carrier protein) reductase, putative	Get druggable targets OG5_129031	All targets in OG5_129031
Schistosoma japonicum	ko:K00461 arachidonate 5-lipoxygenase [EC1.13.11.34], putative	Get druggable targets OG5_127482	All targets in OG5_127482
Schistosoma mansoni	aldehyde dehydrogenase	Get druggable targets OG5_126638	All targets in OG5_126638
Leishmania mexicana	aldehyde dehydrogenase, mitochondrial precursor	Get druggable targets OG5_126638	All targets in OG5_126638
Echinococcus multilocularis	arachidonate 5 lipoxygenase	Get druggable targets OG5_127482	All targets in OG5_127482
Candida albicans	similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11	Get druggable targets OG5_126554	All targets in OG5_126554
Candida albicans	Mitochondrial aldehyde dehydrogenase	Get druggable targets OG5_126638	All targets in OG5_126638
Schistosoma japonicum	ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative	Get druggable targets OG5_126638	All targets in OG5_126638
Schistosoma mansoni	aldehyde dehydrogenase	Get druggable targets OG5_126638	All targets in OG5_126638
Leishmania donovani	3-oxoacyl-(acyl-carrier protein) reductase, putative	Get druggable targets OG5_129031	All targets in OG5_129031
Echinococcus granulosus	3 hydroxyacyl coenzyme A dehydrogenase type 2	Get druggable targets OG5_129031	All targets in OG5_129031
Leishmania major	cytochrome p450-like protein	Get druggable targets OG5_126554	All targets in OG5_126554
Mycobacterium ulcerans	aldehyde dehydrogenase	Get druggable targets OG5_126638	All targets in OG5_126638
Leishmania braziliensis	cytochrome p450-like protein	Get druggable targets OG5_126554	All targets in OG5_126554
Leishmania infantum	cytochrome p450-like protein	Get druggable targets OG5_126554	All targets in OG5_126554
Leishmania infantum	aldehyde dehydrogenase, mitochondrial precursor	Get druggable targets OG5_126638	All targets in OG5_126638
Toxoplasma gondii	aldehyde dehydrogenase	Get druggable targets OG5_126638	All targets in OG5_126638
Schistosoma japonicum	ko:K00022 3-hydroxyacyl-CoA dehydrogenase [EC1.1.1.35], putative	Get druggable targets OG5_129031	All targets in OG5_129031
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	Get druggable targets OG5_129031	All targets in OG5_129031
Neospora caninum	hypothetical protein	Get druggable targets OG5_126638	All targets in OG5_126638
Echinococcus multilocularis	3 hydroxyacyl coenzyme A dehydrogenase type 2	Get druggable targets OG5_129031	All targets in OG5_129031
Leishmania mexicana	3-oxoacyl-(acyl-carrier protein) reductase, putative	Get druggable targets OG5_129031	All targets in OG5_129031
Brugia malayi	Cytochrome P450 family protein	Get druggable targets OG5_126554	All targets in OG5_126554
Schistosoma japonicum	Retinal dehydrogenase 1, putative	Get druggable targets OG5_126638	All targets in OG5_126638
Trypanosoma brucei	cytochrome P450, putative	Get druggable targets OG5_126554	All targets in OG5_126554
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	Get druggable targets OG5_126638	All targets in OG5_126638
Leishmania mexicana	cytochrome p450-like protein	Get druggable targets OG5_126554	All targets in OG5_126554
Mycobacterium ulcerans	cytochrome P450 185A4 Cyp185A4	Get druggable targets OG5_126554	All targets in OG5_126554
Candida albicans	similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11	Get druggable targets OG5_126554	All targets in OG5_126554
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	Get druggable targets OG5_129031	All targets in OG5_129031

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Plasmodium falciparum	3-oxoacyl-[acyl-carrier-protein] reductase	hydroxysteroid (17-beta) dehydrogenase 10	252 aa	251 aa	24.7 %
Mycobacterium tuberculosis	Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1	aldehyde dehydrogenase 1 family, member A1	501 aa	456 aa	33.3 %
Brugia malayi	cytochrome P450	cytochrome P450, family 3, subfamily A, polypeptide 4	502 aa	492 aa	24.2 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Mycobacterium leprae	conserved hypothetical protein	0.0097	0.0151	0.5
Brugia malayi	RE15519p	0.0041	0.0053	0.1619
Schistosoma mansoni	thyroid hormone receptor	0.0012	0.0003	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0097	0.0151	0.0151
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0012	0.0003	0.0001
Chlamydia trachomatis	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase	0.0097	0.0151	0.5
Echinococcus granulosus	lipoxygenase domain containing protein	0.0024	0.0023	0.0021
Trypanosoma cruzi	Histidine phosphatase superfamily (branch 1), putative	0.0097	0.0151	0.0149
Brugia malayi	G-protein coupled receptor	0.0041	0.0053	0.1619
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0012	0.0003	0.0001
Schistosoma mansoni	amine GPCR	0.0041	0.0053	0.005
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0041	0.0053	0.005
Onchocerca volvulus	Protein UBASH3A homolog	0.0097	0.0151	0.0148
Echinococcus granulosus	neuropeptide receptor	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0041	0.0053	0.005
Trypanosoma cruzi	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.577	1	1
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.0073	0.0109	0.1439
Schistosoma mansoni	6-phosphofructokinase	0.577	1	1
Leishmania major	hypothetical protein, conserved	0.0097	0.0151	0.0149
Echinococcus multilocularis	phosphoglycerate mutase	0.0097	0.0151	0.0149
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0041	0.0053	0.005
Echinococcus granulosus	lipoxygenase domain containing protein	0.0024	0.0023	0.0021
Schistosoma mansoni	aldehyde dehydrogenase	0.0073	0.0109	0.0107
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Echinococcus granulosus	FTZ F1 alpha	0.0012	0.0003	0.0001
Onchocerca volvulus	Protein UBASH3A homolog	0.0097	0.0151	0.0148
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Trichomonas vaginalis	conserved hypothetical protein	0.0097	0.0151	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus granulosus	neuropeptide receptor A26	0.0041	0.0053	0.005
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0012	0.0003	0.0003
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0073	0.0109	0.0181
Echinococcus granulosus	phosphoglycerate mutase	0.0097	0.0151	0.0149
Trypanosoma cruzi	metacaspase 5, putative	0.0057	0.008	0.0078
Leishmania major	3-oxoacyl-(acyl-carrier protein) reductase, putative	0.0069	0.0102	0.01
Trypanosoma brucei	JmjC domain, hydroxylase, putative	0.0019	0.0015	0.0012
Echinococcus multilocularis	neuropeptide s receptor	0.0041	0.0053	0.005
Trypanosoma cruzi	6-phosphofructo-2-kinase 1	0.5673	0.9831	0.9831
Mycobacterium tuberculosis	Conserved protein	0.0097	0.0151	1
Onchocerca volvulus	Protein UBASH3A homolog	0.0097	0.0151	0.0148
Echinococcus granulosus	phosphoglycerate mutase	0.0097	0.0151	0.0149
Trypanosoma cruzi	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative	0.0097	0.0151	0.0149
Trypanosoma cruzi	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative	0.0097	0.0151	0.0149
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Onchocerca volvulus		0.0041	0.0053	0.005
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0041	0.0053	0.1619
Brugia malayi	Melatonin receptor type 1A	0.0041	0.0053	0.1619
Schistosoma mansoni	hypothetical protein	0.0097	0.0151	0.0149
Mycobacterium leprae	PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM)	0.0097	0.0151	0.5
Loa Loa (eye worm)	TYRA-2 protein	0.0041	0.0053	0.0053
Echinococcus granulosus	apoptotic protease activating factor 1	0.0132	0.0211	0.0209
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Echinococcus multilocularis	dro:myosuppressin receptor	0.0041	0.0053	0.005
Leishmania major	fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein	0.0097	0.0151	0.0149
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0041	0.0053	0.005
Schistosoma mansoni	ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related	0.0019	0.0015	0.0012
Mycobacterium ulcerans	phosphoglycerate mutase	0.0097	0.0151	0.0252
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0053	0.005
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Trypanosoma cruzi	JmjC domain, hydroxylase, putative	0.0019	0.0015	0.0012
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0053	0.005
Toxoplasma gondii	histone lysine demethylase JMJD6a	0.0019	0.0015	0.0825
Brugia malayi	Serotonin receptor	0.0041	0.0053	0.1619
Mycobacterium leprae	POSSIBLE HYDROLASE MUTT1	0.0097	0.0151	0.5
Trypanosoma cruzi	metacaspase, putative	0.0057	0.008	0.0078
Brugia malayi	Serotonin receptor	0.0041	0.0053	0.1619
Toxoplasma gondii	ICE family protease (caspase) p20 domain-containing protein	0.0057	0.008	0.5254
Giardia lamblia	Hypothetical protein	0.3405	0.5894	1
Plasmodium vivax	phosphoglycerate mutase, putative	0.0097	0.0151	1
Brugia malayi	UBASH3A protein homolog	0.0097	0.0151	0.4816
Brugia malayi	hypothetical protein	0.0041	0.0053	0.1619
Echinococcus multilocularis	neuropeptides capa receptor	0.0041	0.0053	0.005
Trypanosoma cruzi	Histidine phosphatase superfamily (branch 1), putative	0.0097	0.0151	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0012	0.0003	0.0003
Schistosoma mansoni	amine GPCR	0.0041	0.0053	0.005
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0053	0.005
Echinococcus multilocularis	lysine specific demethylase 6a	0.0019	0.0015	0.0012
Loa Loa (eye worm)	hypothetical protein	0.0012	0.0003	0.0003
Schistosoma mansoni	RAR-like nuclear receptor	0.0012	0.0003	0.0001
Echinococcus granulosus	JmjC domain containing protein 4	0.0019	0.0015	0.0012
Plasmodium vivax	JmjC domain containing protein	0.0019	0.0015	0.0825
Brugia malayi	MH2 domain containing protein	0.0116	0.0184	0.5885
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0041	0.0053	0.005
Trypanosoma cruzi	glycerolphosphate mutase, putative	0.0097	0.0151	0.0149
Echinococcus multilocularis	phd:f box containing protein	0.0019	0.0015	0.0012
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0041	0.0053	0.005
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0041	0.0053	0.0053
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0041	0.0053	0.005
Trichomonas vaginalis	phosphoglycerate mutase, putative	0.0097	0.0151	1
Echinococcus granulosus	g protein coupled receptor	0.0041	0.0053	0.005
Leishmania major	glycerolphosphate mutase, putative	0.0097	0.0151	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus multilocularis	G protein coupled receptor 139	0.0041	0.0053	0.005
Trypanosoma brucei	Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative	0.0097	0.0151	0.0149
Trypanosoma cruzi	Histidine phosphatase superfamily (branch 1), putative	0.0097	0.0151	0.0149
Brugia malayi	follicle stimulating hormone receptor	0.0041	0.0053	0.1619
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0041	0.0053	0.005
Onchocerca volvulus		0.0097	0.0151	0.0148
Echinococcus granulosus	biogenic amine 5HT receptor	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0015	0.0015
Echinococcus multilocularis	allatostatin A receptor	0.0041	0.0053	0.005
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0041	0.0053	0.005
Trypanosoma cruzi	phosphoglycerate mutase, putative	0.0097	0.0151	0.0149
Brugia malayi	larval opioid receptor	0.0041	0.0053	0.1619
Mycobacterium tuberculosis	Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase)	0.0097	0.0151	1
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0041	0.0053	0.005
Echinococcus multilocularis	somatostatin receptor	0.0041	0.0053	0.005
Brugia malayi	hypothetical protein	0.0024	0.0023	0.0656
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0023	0.0023
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0041	0.0053	0.005
Onchocerca volvulus		0.0041	0.0053	0.005
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0012	0.0003	0.0001
Trypanosoma cruzi	metacaspase 5, putative	0.0057	0.008	0.0078
Brugia malayi	jmjC domain containing protein	0.0019	0.0015	0.0381
Schistosoma mansoni	amine GPCR	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0012	0.0003	0.0001
Mycobacterium ulcerans	phosphohistidine phosphatase SixA	0.0097	0.0151	0.0252
Schistosoma mansoni	aldehyde dehydrogenase	0.0073	0.0109	0.0107
Echinococcus granulosus	caspase 3 apoptosis cysteine peptidase	0.0057	0.008	0.0078
Trypanosoma brucei	phosphoglycerate mutase, putative	0.0097	0.0151	0.0149
Entamoeba histolytica	phosphoglycerate mutase family protein. putative	0.0097	0.0151	0.0252
Brugia malayi	hypothetical protein	0.0041	0.0053	0.1619
Schistosoma mansoni	hypothetical protein	0.0097	0.0151	0.0149
Mycobacterium leprae	conserved hypothetical protein	0.0097	0.0151	0.5
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0041	0.0053	0.1619
Trypanosoma cruzi	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.577	1	1
Mycobacterium ulcerans	phosphoglyceromutase	0.0097	0.0151	0.0252
Echinococcus granulosus	ecdysone induced protein 78C	0.0012	0.0003	0.0001
Toxoplasma gondii	phosphoglycerate mutase PGMII	0.0097	0.0151	1
Mycobacterium leprae	Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase)	0.0097	0.0151	0.5
Schistosoma mansoni	adenoreceptor	0.0041	0.0053	0.005
Loa Loa (eye worm)	melatonin receptor type 1A	0.0041	0.0053	0.0053
Leishmania major	hypothetical protein, conserved	0.0097	0.0151	0.0149
Trichomonas vaginalis	phosphoglycerate mutase, putative	0.0097	0.0151	1
Mycobacterium ulcerans	phosphoglycerate mutase	0.0097	0.0151	0.0252
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Trypanosoma brucei	Histidine phosphatase superfamily (branch 1), putative	0.0097	0.0151	0.0149
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0012	0.0003	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0053	0.005
Echinococcus multilocularis	serine:threonine protein phosphatase PGAM5	0.0097	0.0151	0.0149
Loa Loa (eye worm)	CYP4Cod1	0.0015	0.0007	0.0007
Echinococcus multilocularis	g protein coupled receptor	0.0041	0.0053	0.005
Schistosoma mansoni	neuropeptide F-like receptor	0.0041	0.0053	0.005
Brugia malayi	hypothetical protein	0.0041	0.0053	0.1619
Schistosoma mansoni	phosphatidylserine receptor	0.0019	0.0015	0.0012
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Loa Loa (eye worm)	doublecortin family protein	0.0024	0.0023	0.0023
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0041	0.0053	0.0053
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0012	0.0003	0.0001
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0041	0.0053	0.005
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0041	0.0053	0.005
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0041	0.0053	0.005
Trypanosoma cruzi	metacaspase, putative	0.0057	0.008	0.0078
Onchocerca volvulus		0.0041	0.0053	0.005
Trypanosoma brucei	Metacaspase-4	0.0057	0.008	0.0078
Plasmodium falciparum	JmjC domain-containing protein, putative	0.0019	0.0015	0.0825
Schistosoma mansoni	growth hormone secretagogue receptor	0.0041	0.0053	0.005
Onchocerca volvulus		0.0097	0.0151	0.0148
Loa Loa (eye worm)	G-protein coupled receptor	0.0041	0.0053	0.0053
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus granulosus	arachidonate 5 lipoxygenase	0.0142	0.0229	0.0227
Loa Loa (eye worm)	hypothetical protein	0.0097	0.0151	0.0151
Toxoplasma gondii	phosphoglycerate mutase family protein	0.0097	0.0151	1
Echinococcus granulosus	g-protein coupled receptor	0.0041	0.0053	0.005
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0012	0.0003	0.0001
Echinococcus granulosus	jumonji domain containing 1A	0.0019	0.0015	0.0012
Mycobacterium ulcerans	cytochrome P450 185A4 Cyp185A4	0.0015	0.0007	0.0009
Brugia malayi	sulfakinin receptor protein	0.0041	0.0053	0.1619
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0041	0.0053	0.005
Brugia malayi	jmjC domain containing protein	0.0071	0.0105	0.3325
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus multilocularis	JmjC domain containing protein 4	0.0019	0.0015	0.0012
Trypanosoma brucei	Histidine phosphatase superfamily (branch 1), putative	0.0097	0.0151	0.0149
Echinococcus multilocularis	sex peptide receptor	0.0041	0.0053	0.005
Onchocerca volvulus		0.0041	0.0053	0.005
Schistosoma mansoni	caspase-7 (C14 family)	0.0189	0.031	0.0308
Echinococcus granulosus	neuropeptide Y receptor	0.0041	0.0053	0.005
Echinococcus granulosus	7tm_1 domain containing protein	0.0041	0.0053	0.005
Echinococcus granulosus	caspase 8	0.0057	0.008	0.0078
Schistosoma mansoni	phosphoglycerate mutase	0.0097	0.0151	0.0149
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0041	0.0053	0.005
Toxoplasma gondii	phosphoglycerate mutase	0.0097	0.0151	1
Echinococcus multilocularis	phosphoglycerate mutase	0.0097	0.0151	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus multilocularis	phosphoglycerate mutase	0.0097	0.0151	0.0149
Schistosoma mansoni	polycystin 1-related	0.0024	0.0023	0.0021
Onchocerca volvulus		0.0041	0.0053	0.005
Trypanosoma cruzi	phosphoglycerate mutase family member 5, putative	0.0097	0.0151	0.0149
Echinococcus multilocularis	serotonin receptor	0.0041	0.0053	0.005
Toxoplasma gondii	ICE family protease (caspase) p20 domain-containing protein	0.0057	0.008	0.5254
Loa Loa (eye worm)	jmjC domain-containing protein	0.0019	0.0015	0.0015
Echinococcus multilocularis	RUN	0.0024	0.0023	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0041	0.0053	0.005
Echinococcus granulosus	caspase 2	0.0189	0.031	0.0308
Echinococcus granulosus	g protein coupled receptor	0.0041	0.0053	0.005
Echinococcus granulosus	neuropeptide Y receptor	0.0041	0.0053	0.005
Brugia malayi	Dopamine receptor protein 2	0.0041	0.0053	0.1619
Mycobacterium tuberculosis	Probable conserved lipoprotein LpqD	0.0097	0.0151	1
Mycobacterium ulcerans	lipoprotein LpqD	0.0097	0.0151	0.0252
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0041	0.0053	0.005
Schistosoma mansoni	neuropeptide receptor	0.0041	0.0053	0.005
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0071	0.0105	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0073	0.0109	0.0107
Trypanosoma cruzi	Histidine phosphatase superfamily (branch 1), putative	0.0097	0.0151	0.0149
Toxoplasma gondii	ICE family protease (caspase) p20 domain-containing protein	0.0057	0.008	0.5254
Schistosoma mansoni	nuclear hormone receptor	0.0012	0.0003	0.0001
Onchocerca volvulus		0.0132	0.0211	0.0209
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0041	0.0053	0.005
Brugia malayi	hypothetical protein	0.0041	0.0053	0.1619
Schistosoma mansoni	neuropeptide f receptor 76f	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0015	0.0015
Brugia malayi	Cell death protein 3 precursor	0.0189	0.031	1
Echinococcus granulosus	serine:threonine protein phosphatase PGAM5	0.0097	0.0151	0.0149
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0041	0.0053	0.1619
Entamoeba histolytica	phosphoglycerate mutase family protein, putative	0.0097	0.0151	0.0252
Echinococcus multilocularis	orexin receptor type 2	0.0041	0.0053	0.005
Trypanosoma cruzi	metacaspase, putative	0.0057	0.008	0.0078
Onchocerca volvulus		0.577	1	1
Echinococcus multilocularis	neuropeptides capa receptor	0.0041	0.0053	0.005
Schistosoma mansoni	histamine h1 receptor	0.0041	0.0053	0.005
Echinococcus multilocularis	lipoxygenase domain containing protein	0.0024	0.0023	0.0021
Mycobacterium ulcerans	hypothetical protein	0.3405	0.5894	1
Echinococcus multilocularis	lipoxygenase domain containing protein	0.0024	0.0023	0.0021
Brugia malayi	Cytochrome P450 family protein	0.0015	0.0007	0.015
Toxoplasma gondii	phosphoglycerate mutase family protein	0.0097	0.0151	1
Echinococcus multilocularis	g protein coupled receptor	0.0041	0.0053	0.005
Echinococcus granulosus	phosphoglycerate mutase	0.0097	0.0151	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Schistosoma mansoni	coup transcription factor	0.0012	0.0003	0.0001
Echinococcus multilocularis	Jumonji, AT rich interactive domain 1B	0.0019	0.0015	0.0012
Brugia malayi	G protein-coupled receptor F59B2.13	0.0041	0.0053	0.1619
Plasmodium falciparum	phosphoglucomutase-2	0.0097	0.0151	1
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0069	0.0102	0.0169
Toxoplasma gondii	aldehyde dehydrogenase	0.0073	0.0109	0.7184
Brugia malayi	hypothetical protein	0.0041	0.0053	0.1619
Loa Loa (eye worm)	phosphoglycerate mutase	0.0097	0.0151	0.0151
Leishmania major	hypothetical protein, conserved	0.0097	0.0151	0.0149
Echinococcus granulosus	neuropeptide s receptor	0.0041	0.0053	0.005
Toxoplasma gondii	phosphoglycerate mutase family protein	0.0097	0.0151	1
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0097	0.0151	1
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0012	0.0003	0.0003
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0069	0.0102	0.0169
Echinococcus multilocularis	neuropeptide receptor	0.0041	0.0053	0.005
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0041	0.0053	0.005
Trypanosoma brucei	metacaspase MCA3	0.0057	0.008	0.0078
Loa Loa (eye worm)	jmjC domain-containing protein	0.0019	0.0015	0.0015
Plasmodium vivax	hypothetical protein, conserved	0.0057	0.008	0.5254
Echinococcus multilocularis	neuropeptide receptor A26	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.3308	0.5725	0.5725
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0012	0.0003	0.0001
Trichomonas vaginalis	phosphoglycerate mutase, putative	0.0097	0.0151	1
Schistosoma mansoni	hypothetical protein	0.0041	0.0053	0.005
Loa Loa (eye worm)	G-protein coupled receptor	0.0041	0.0053	0.0053
Brugia malayi	G protein-coupled receptor	0.0041	0.0053	0.1619
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0041	0.0053	0.005
Brugia malayi	hypothetical protein	0.0041	0.0053	0.1619
Leishmania major	phosphoglycerate mutase family member 5, putative	0.0097	0.0151	0.0149
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Echinococcus multilocularis	g protein coupled receptor	0.0041	0.0053	0.005
Brugia malayi	ORL1-like opioid receptor	0.0041	0.0053	0.1619
Brugia malayi	neuropeptide F receptor	0.0041	0.0053	0.1619
Trypanosoma brucei	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative	0.0097	0.0151	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Brugia malayi	Dopamine receptor protein 1	0.0041	0.0053	0.1619
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0211	0.0211
Brugia malayi	jmjC domain containing protein	0.0071	0.0105	0.3325
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0073	0.0109	0.0107
Echinococcus multilocularis	fmrfamide receptor	0.0041	0.0053	0.005
Trypanosoma cruzi	metacaspase, putative	0.0057	0.008	0.0078
Echinococcus multilocularis	lysine specific demethylase 5A	0.0071	0.0105	0.0103
Schistosoma mansoni	rab6-interacting	0.0024	0.0023	0.0021
Trichomonas vaginalis	phosphoglycerate mutase, putative	0.0097	0.0151	1
Schistosoma mansoni	opsin-like receptor	0.0041	0.0053	0.005
Echinococcus granulosus	serotonin receptor	0.0041	0.0053	0.005
Trypanosoma cruzi	cytochrome P450, putative	0.0015	0.0007	0.0005
Mycobacterium ulcerans	hypothetical protein	0.0097	0.0151	0.0252
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0012	0.0003	0.0001
Echinococcus granulosus	hypothetical protein	0.0041	0.0053	0.005
Onchocerca volvulus		0.0041	0.0053	0.005
Schistosoma mansoni	biogenic amine receptor	0.0041	0.0053	0.005
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0041	0.0053	0.005
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0053	0.005
Echinococcus granulosus	lysine specific demethylase 6a	0.0019	0.0015	0.0012
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Schistosoma mansoni	rab6-interacting	0.0024	0.0023	0.0021
Plasmodium falciparum	LCCL domain-containing protein	0.0024	0.0023	0.1394
Schistosoma mansoni	hypothetical protein	0.0132	0.0211	0.0209
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0041	0.0053	0.005
Echinococcus granulosus	fmrfamide receptor	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0012	0.0003	0.0003
Echinococcus granulosus	tm gpcr rhodopsin	0.0041	0.0053	0.005
Echinococcus granulosus	neuropeptides capa receptor	0.0041	0.0053	0.005
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0071	0.0105	0.0103
Schistosoma mansoni	caspase-7 (C14 family)	0.0057	0.008	0.0078
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0053	0.005
Loa Loa (eye worm)	cytochrome P450 family protein	0.0015	0.0007	0.0007
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0041	0.0053	0.005
Entamoeba histolytica	phosphoglycerate mutase family protein, putative	0.0097	0.0151	0.0252
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0012	0.0003	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0041	0.0053	0.005
Brugia malayi	jmjC domain containing protein	0.0019	0.0015	0.0381
Trypanosoma cruzi	Histidine phosphatase superfamily (branch 1), putative	0.0097	0.0151	0.0149
Trypanosoma brucei	metacaspase 5, putative	0.0057	0.008	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus multilocularis	neuropeptide Y receptor	0.0041	0.0053	0.005
Plasmodium vivax	multidomain scavenger receptor, putative	0.0024	0.0023	0.1394
Leishmania major	hypothetical protein, conserved	0.0019	0.0015	0.0012
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0012	0.0003	0.0001
Brugia malayi	putative neuropeptide receptor NPR1	0.0041	0.0053	0.1619
Onchocerca volvulus		0.0041	0.0053	0.005
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0041	0.0053	0.005
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0012	0.0003	0.0001
Trypanosoma brucei	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.577	1	1
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0041	0.0053	0.005
Brugia malayi	hypothetical protein	0.0041	0.0053	0.1619
Loa Loa (eye worm)	jmjC domain-containing protein	0.0071	0.0105	0.0105
Brugia malayi	G-protein coupled receptor	0.0041	0.0053	0.1619
Echinococcus multilocularis	serotonin receptor	0.0041	0.0053	0.005
Plasmodium falciparum	metacaspase-like protein	0.0057	0.008	0.5254
Treponema pallidum	phosphoglyceromutase	0.0097	0.0151	0.5
Onchocerca volvulus		0.0041	0.0053	0.005
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0012	0.0003	0.0003
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0041	0.0053	0.0053
Onchocerca volvulus		0.0097	0.0151	0.0148
Schistosoma mansoni	phd/f-box containing protein	0.0019	0.0015	0.0012
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0041	0.0053	0.1619
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0012	0.0003	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0097	0.0151	0.0151
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0041	0.0053	0.005
Mycobacterium tuberculosis	Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM)	0.0097	0.0151	1
Brugia malayi	hypothetical protein	0.0041	0.0053	0.1619
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Trichomonas vaginalis	phosphoglycerate mutase, putative	0.0097	0.0151	1
Schistosoma mansoni	opsin-like receptor	0.0041	0.0053	0.005
Echinococcus multilocularis	caspase 2	0.0189	0.031	0.0308
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0012	0.0003	0.0001
Echinococcus multilocularis	g-protein coupled receptor	0.0041	0.0053	0.005
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0012	0.0003	0.0003
Schistosoma mansoni	myosin xvIII	0.0041	0.0053	0.005
Leishmania major	phosphoglycerate mutase, putative	0.0097	0.0151	0.0149
Mycobacterium tuberculosis	Glucosyl-3-phosphoglycerate phosphatase GpgP	0.0097	0.0151	1
Schistosoma mansoni	amine GPCR	0.0041	0.0053	0.005
Trypanosoma cruzi	phosphoglycerate mutase, putative	0.0097	0.0151	0.0149
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0041	0.0053	0.005
Trypanosoma brucei	phosphoglycerate mutase protein, putative	0.0097	0.0151	0.0149
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0071	0.0105	0.0103
Onchocerca volvulus		0.0041	0.0053	0.005
Echinococcus granulosus	Polycystic kidney disease protein	0.0024	0.0023	0.0021
Brugia malayi	putative neuropeptide receptor	0.0041	0.0053	0.1619
Schistosoma mansoni	subfamily C14A unassigned peptidase (C14 family)	0.0057	0.008	0.0078
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0012	0.0003	0.0001
Schistosoma mansoni	neuropeptide receptor	0.0041	0.0053	0.005
Echinococcus multilocularis	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0069	0.0102	0.01
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0012	0.0003	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Mycobacterium leprae	conserved hypothetical protein	0.0097	0.0151	0.5
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0041	0.0053	0.1619
Echinococcus granulosus	lysine specific demethylase 5A	0.0071	0.0105	0.0103
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Brugia malayi	phosphoglycerate mutase family protein	0.0097	0.0151	0.4816
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0041	0.0053	0.005
Schistosoma mansoni	3-hydroxyacyl-CoA dehydrogenase	0.0069	0.0102	0.01
Trypanosoma brucei	metacaspase	0.0057	0.008	0.0078
Echinococcus multilocularis	jumonji domain containing 1A	0.0019	0.0015	0.0012
Echinococcus granulosus	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0069	0.0102	0.01
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0012	0.0003	0.0003
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0041	0.0053	0.005
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0041	0.0053	0.0053
Schistosoma mansoni	neuropeptide F-like receptor	0.0041	0.0053	0.005
Leishmania major	hypothetical protein, unknown function	0.0097	0.0151	0.0149
Brugia malayi	3-hydroxyacyl-CoA dehydrogenase type II	0.0069	0.0102	0.3226
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0041	0.0053	0.005
Echinococcus granulosus	caspase	0.0057	0.008	0.0078
Schistosoma mansoni	hypothetical protein	0.0097	0.0151	0.0149
Leishmania major	cytochrome p450-like protein	0.0015	0.0007	0.0005
Brugia malayi	hypothetical protein	0.0132	0.0211	0.6788
Trypanosoma cruzi	glycerolphosphate mutase, putative	0.0097	0.0151	0.0149
Schistosoma mansoni	hypothetical protein	0.0097	0.0151	0.0149
Echinococcus granulosus	Jumonji AT rich interactive domain 1B	0.0019	0.0015	0.0012
Mycobacterium tuberculosis	Possible hydrolase MutT1	0.0097	0.0151	1
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Schistosoma mansoni	hypothetical protein	0.0024	0.0023	0.0021
Brugia malayi	phosphoglycerate mutase family protein	0.0097	0.0151	0.4816
Schistosoma mansoni	jumonji domain containing protein	0.0019	0.0015	0.0012
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Schistosoma mansoni	biogenic amine receptor	0.0041	0.0053	0.005
Brugia malayi	hypothetical protein	0.0041	0.0053	0.1619
Plasmodium vivax	phosphoglucomutase-2, putative	0.0097	0.0151	1
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0041	0.0053	0.005
Echinococcus multilocularis	phosphoglycerate mutase	0.0097	0.0151	0.0149
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0041	0.0053	0.0053
Toxoplasma gondii	phosphoglycerate mutase family protein	0.0097	0.0151	1
Schistosoma mansoni	lipoxygenase	0.01	0.0155	0.0152
Echinococcus multilocularis	apoptotic protease activating factor 1	0.0132	0.0211	0.0209
Onchocerca volvulus		0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Entamoeba histolytica	phosphoglycerate mutase family protein, putative	0.3405	0.5894	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0041	0.0053	0.005
Echinococcus granulosus	phosphoglycerate mutase	0.0097	0.0151	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Brugia malayi	Dopamine receptor	0.0041	0.0053	0.1619
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0041	0.0053	0.005
Brugia malayi	hypothetical protein	0.0041	0.0053	0.1619
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0053	0.005
Mycobacterium leprae	probable isochorismate synthase EntC	0.0097	0.0151	0.5
Loa Loa (eye worm)	hypothetical protein	0.0012	0.0003	0.0003
Loa Loa (eye worm)	hypothetical protein	0.0012	0.0003	0.0003
Loa Loa (eye worm)	jmjC domain-containing protein	0.0019	0.0015	0.0015
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Brugia malayi	jmjC domain containing protein	0.0019	0.0015	0.0381
Loa Loa (eye worm)	hypothetical protein	0.0012	0.0003	0.0003
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0073	0.0109	0.0181
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Trypanosoma cruzi	cytochrome P450, putative	0.0015	0.0007	0.0005
Echinococcus granulosus	allatostatin A receptor	0.0041	0.0053	0.005
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0041	0.0053	0.1619
Loa Loa (eye worm)	3-hydroxyacyl-CoA dehydrogenase type II	0.0065	0.0094	0.0094
Trypanosoma brucei	glycerolphosphate mutase, putative	0.0097	0.0151	0.0149
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0012	0.0003	0.0001
Mycobacterium ulcerans	fructose-2,6-bisphosphatase GpmB	0.3405	0.5894	1
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0073	0.0109	0.0107
Trichomonas vaginalis	conserved hypothetical protein	0.0097	0.0151	1
Leishmania major	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.577	1	1
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus granulosus	biogenic amine 5HT receptor	0.0041	0.0053	0.005
Echinococcus granulosus	g protein coupled receptor	0.0041	0.0053	0.005
Schistosoma mansoni	biogenic amine receptor	0.0041	0.0053	0.005
Brugia malayi	Cytochrome P450 family protein	0.0015	0.0007	0.015
Brugia malayi	jmjC domain containing protein	0.0019	0.0015	0.0381
Echinococcus multilocularis	neuropeptide receptor	0.0041	0.0053	0.005
Brugia malayi	GnHR receptor homolog	0.0041	0.0053	0.1619
Echinococcus granulosus	phosphoglycerate mutase	0.0097	0.0151	0.0149
Echinococcus granulosus	sex peptide receptor	0.0041	0.0053	0.005
Schistosoma mansoni	hypothetical protein	0.0041	0.0053	0.005
Echinococcus multilocularis	Polycystic kidney disease protein	0.0024	0.0023	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Toxoplasma gondii	histone lysine demethylase JMJC1/KDM5D/JARID1D	0.0019	0.0015	0.0825
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0015	0.0015
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus granulosus	7TM GPCR rhodopsin	0.0041	0.0053	0.005
Loa Loa (eye worm)	transcription factor SMAD2	0.0116	0.0184	0.0184
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0041	0.0053	0.005
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0012	0.0003	0.0001
Echinococcus granulosus	neuropeptide FF receptor 2	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.577	1	1
Trypanosoma cruzi	phosphoglycerate mutase protein, putative	0.0097	0.0151	0.0149
Echinococcus multilocularis	arachidonate 5 lipoxygenase	0.0142	0.0229	0.0227
Echinococcus multilocularis	neuropeptide Y receptor	0.0041	0.0053	0.005
Mycobacterium ulcerans	hypothetical protein	0.0097	0.0151	0.0252
Trypanosoma cruzi	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.2462	0.4256	0.4255
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0012	0.0003	0.0003
Leishmania major	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.5673	0.9831	0.9831
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus multilocularis	serine:threonine protein phosphatase PGAM5	0.0097	0.0151	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0097	0.0151	0.0151
Brugia malayi	hypothetical protein	0.0024	0.0023	0.0656
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0053	0.005
Schistosoma mansoni	hypothetical protein	0.0041	0.0053	0.005
Trypanosoma cruzi	phosphoglycerate mutase family member 5, putative	0.0097	0.0151	0.0149
Schistosoma mansoni	phosphoglycerate mutase	0.0097	0.0151	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0189	0.031	0.031
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0041	0.0053	0.005
Echinococcus granulosus	RUN	0.0024	0.0023	0.0021
Echinococcus granulosus	neuropeptides capa receptor	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.5673	0.9831	0.9831
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0012	0.0003	0.0001
Trypanosoma cruzi	JmjC domain, hydroxylase, putative	0.0019	0.0015	0.0012
Echinococcus multilocularis	ecdysone induced protein 78C	0.0012	0.0003	0.0001
Schistosoma mansoni	neuropeptide receptor	0.0041	0.0053	0.005
Loa Loa (eye worm)	steroid hormone receptor	0.0012	0.0003	0.0003
Trypanosoma brucei	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.2462	0.4256	0.4255
Leishmania major	phosphoglycerate mutase protein, putative	0.0097	0.0151	0.0149
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0041	0.0053	0.005
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0073	0.0109	0.0181
Echinococcus multilocularis	caspase 8	0.0057	0.008	0.0078
Mycobacterium tuberculosis	PE-PGRS family protein PE_PGRS11	0.0097	0.0151	1
Trypanosoma brucei	cytochrome P450, putative	0.0015	0.0007	0.0005
Trypanosoma cruzi	phosphoglycerate mutase protein, putative	0.0097	0.0151	0.0149
Schistosoma mansoni	caspase-3 (C14 family)	0.0057	0.008	0.0078
Echinococcus granulosus	G protein coupled receptor 139	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0012	0.0003	0.0003
Echinococcus multilocularis	6 phosphofructo 2 kinase:fructose 2	0.577	1	1
Echinococcus multilocularis	caspase	0.0057	0.008	0.0078
Onchocerca volvulus		0.0041	0.0053	0.005
Echinococcus multilocularis	caspase 3, apoptosis cysteine peptidase	0.0057	0.008	0.0078
Schistosoma mansoni	lipoxygenase	0.0142	0.0229	0.0227
Echinococcus multilocularis	phosphoglycerate mutase	0.0097	0.0151	0.0149
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0041	0.0053	0.005
Schistosoma mansoni	opsin-like receptor	0.0041	0.0053	0.005
Mycobacterium ulcerans	acid phosphatase	0.0097	0.0151	0.0252
Schistosoma mansoni	loxhd1	0.0024	0.0023	0.0021
Onchocerca volvulus		0.0041	0.0053	0.005
Echinococcus granulosus	phd:f box containing protein	0.0019	0.0015	0.0012
Echinococcus granulosus	dro:myosuppressin receptor	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Onchocerca volvulus		0.0041	0.0053	0.005
Onchocerca volvulus		0.0024	0.0023	0.002
Schistosoma mansoni	jumonji domain containing protein	0.0071	0.0105	0.0103
Echinococcus multilocularis	phosphoglycerate mutase	0.0097	0.0151	0.0149
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Echinococcus granulosus	orexin receptor type 2	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Loa Loa (eye worm)	neuropeptide F receptor	0.0041	0.0053	0.0053
Onchocerca volvulus		0.0024	0.0023	0.002
Onchocerca volvulus		0.0041	0.0053	0.005
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0057	0.008	0.008
Echinococcus granulosus	neuropeptide receptor	0.0041	0.0053	0.005
Mycobacterium ulcerans	bifunctional RNase H/acid phosphatase	0.0097	0.0151	0.0252
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0041	0.0053	0.005
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0071	0.0105	0.0103
Leishmania major	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein	0.2462	0.4256	0.4255
Echinococcus multilocularis	fmrfamide receptor	0.0041	0.0053	0.005
Loa Loa (eye worm)	MH2 domain-containing protein	0.0116	0.0184	0.0184
Mycobacterium ulcerans	hydrolase MutT1	0.0097	0.0151	0.0252
Schistosoma mansoni	hypothetical protein	0.0041	0.0053	0.005
Schistosoma mansoni	thyroid hormone receptor	0.0012	0.0003	0.0001
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0012	0.0003	0.0001
Mycobacterium tuberculosis	Conserved protein	0.0097	0.0151	1
Loa Loa (eye worm)	hypothetical protein	0.0012	0.0003	0.0003
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0012	0.0003	0.0003
Schistosoma mansoni	hypothetical protein	0.0097	0.0151	0.0149
Trypanosoma brucei	6-phosphofructo-2-kinase 2	0.5673	0.9831	0.9831
Mycobacterium leprae	Possible phosphoglycerate mutase	0.0097	0.0151	0.5
Brugia malayi	mucosa associated lymphoid tissue lymphoma translocation protein 1	0.0057	0.008	0.2522
Loa Loa (eye worm)	cytochrome P450 family protein	0.0015	0.0007	0.0007
Trypanosoma cruzi	6-phosphofructo-2-kinase 1	0.5673	0.9831	0.9831
Schistosoma mansoni	amine GPCR	0.0041	0.0053	0.005
Trypanosoma brucei	metacaspase MCA2	0.0057	0.008	0.0078
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0041	0.0053	0.005
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0041	0.0053	0.005
Echinococcus granulosus	serine:threonine protein phosphatase PGAM5	0.0097	0.0151	0.0149
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0012	0.0003	0.0001
Schistosoma mansoni	protein phosphatase 2C	0.0019	0.0015	0.0012
Echinococcus granulosus	somatostatin receptor	0.0041	0.0053	0.005
Trypanosoma brucei	Histidine phosphatase superfamily (branch 1), putative	0.0097	0.0151	0.0149
Schistosoma mansoni	neuropeptide receptor	0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Brugia malayi	neuropeptide F receptor	0.0041	0.0053	0.1619
Echinococcus multilocularis	FTZ F1 alpha	0.0012	0.0003	0.0001
Plasmodium falciparum	phosphoglycerate mutase, putative	0.0097	0.0151	1
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0023	0.0023
Schistosoma mansoni	retinoic acid receptor RXR	0.0012	0.0003	0.0001
Onchocerca volvulus	Protein UBASH3A homolog	0.0097	0.0151	0.0148
Onchocerca volvulus		0.0041	0.0053	0.005
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0053	0.0053
Onchocerca volvulus		0.0041	0.0053	0.005
Leishmania major	metacaspase, putative	0.0057	0.008	0.0078
Echinococcus granulosus	tm gpcr rhodopsin	0.0041	0.0053	0.005
Schistosoma mansoni	hypothetical protein	0.0097	0.0151	0.0149
Brugia malayi	Doublecortin family protein	0.0024	0.0023	0.0656
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0053	0.005
Echinococcus granulosus	tm gpcr rhodopsin	0.0041	0.0053	0.005
Plasmodium vivax	metacaspase 1, putative	0.0057	0.008	0.5254
Brugia malayi	AKH receptor	0.0041	0.0053	0.1619
Giardia lamblia	Hypothetical protein	0.3405	0.5894	1
Plasmodium falciparum	metacaspase 1	0.0057	0.008	0.5254
Onchocerca volvulus	Cell death protein 3 homolog	0.0189	0.031	0.0307
Loa Loa (eye worm)	neuropeptide F receptor	0.0041	0.0053	0.0053
Onchocerca volvulus		0.0041	0.0053	0.005
Trypanosoma cruzi	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.2462	0.4256	0.4255
Mycobacterium leprae	PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE)	0.0097	0.0151	0.5

Activities

Activity type	Activity value	Assay description	Source	Reference
Activity (functional)	= 16 %	Vascular activity in KPSS precontracted Sprague-Dawley rat thoracic aorta assessed as endothelium dependent relaxation	ChEMBL.	18307286
Activity (functional)	= 51 %	DPPH scavenging activity in Sprague-Dawley rat thoracic aorta at 100 uM relative to control	ChEMBL.	18307286
Activity (binding)	= 86 %	Inhibition of recombinant human CK2 using RRRDDDSDDD as substrate assessed as residual activity at 10 uM after 20 mins by beta counting analysis in presence of [gamma-labeled 32P]ATP relative to control	ChEMBL.	24011954
Activity (functional)	= 89 %	Antioxidant activity in Sprague-Dawley rat thoracic aorta assessed as superoxide levels at 10 uM by lucigenin-enhanced chemiluminescence assay relative to control	ChEMBL.	18307286
Activity (functional)	= 91 %	Antioxidant activity in Sprague-Dawley rat thoracic aorta assessed as superoxide levels at 10 uM by NBT assay relative to control	ChEMBL.	18307286
Activity (functional)	= 96 %	Cytotoxicity against human HCT116 cells assessed as cell viability at 15 uM after 48 hrs by MTT assay relative to control	ChEMBL.	23771043
Activity (functional)	= 115 %	Inhibition of prostate specific antigen expression in human 22Rv1 cells assessed as PSA protein level at 20 uM after 72 hrs by densitometry relative to untreated control	ChEMBL.	22789812
IC50 (binding)	> 30 uM	Inhibition of recombinant human CK2 using RRRDDDSDDD as substrate after 20 mins by beta counting analysis in presence of [gamma-labeled 32P]ATP	ChEMBL.	24011954
Inhibition (binding)		Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 up to 10 uM preincubated for 30 mins before Hoechst 33342 addition measured after 120 mins by fluorescence assay	ChEMBL.	23851114
Inhibition (binding)		Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A up to 10 uM preincubated for 30 mins before pheophorbide-A addition measured after 120 mins by flow cytometry	ChEMBL.	23851114
Log EC50 (functional)	0	Vascular activity in KPSS precontracted Sprague-Dawley rat thoracic aorta assessed as endothelium dependent relaxation	ChEMBL.	18307286
Potency (functional)	1.5849 uM	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2312, AID2537, AID2702]	ChEMBL.	No reference
Potency (functional)	= 2.8184 um	PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	= 3.1623 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (ADMET)	= 3.9811 um	PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ]	ChEMBL.	No reference
Potency (ADMET)	= 3.9811 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ]	ChEMBL.	No reference
Potency (functional)	= 7.9433 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	= 19.9526 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))]	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL406834
PubChem: 97141
Search by Saint Jude

Bibliographic References

3 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 522956