Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | epidermal growth factor receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.001 | 0 | 0.5 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0057 | 0.28 | 0.3305 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0058 | 0.2815 | 0.2815 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.018 | 1 | 1 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0097 | 0.5114 | 0.5114 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.018 | 1 | 1 |
Leishmania major | 0.0154 | 0.8473 | 1 | |
Toxoplasma gondii | fructose-bisphospatase II | 0.0154 | 0.8473 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.018 | 1 | 1 |
Brugia malayi | fructose-1,6-bisphosphatase | 0.0154 | 0.8473 | 0.7875 |
Entamoeba histolytica | ABC transporter, putative | 0.001 | 0 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.5055 | 0.5055 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.5114 | 0.5114 |
Toxoplasma gondii | fructose-bisphospatase I | 0.0057 | 0.28 | 0.3305 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0097 | 0.5114 | 0.5114 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0154 | 0.8473 | 0.8473 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0154 | 0.8473 | 0.8473 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.001 | 0 | 0.5 |
Plasmodium vivax | ABC transporter G family member 2, putative | 0.001 | 0 | 0.5 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0154 | 0.8473 | 1 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0154 | 0.8473 | 0.8473 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0058 | 0.2815 | 0.2815 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.5114 | 0.5114 |
Echinococcus granulosus | insulin receptor | 0.0058 | 0.2815 | 0.2815 |
Trypanosoma brucei | sedoheptulose-1,7-bisphosphatase | 0.0057 | 0.28 | 0.3305 |
Echinococcus multilocularis | 0.0056 | 0.2709 | 0.2709 | |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0097 | 0.5114 | 0.5114 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0154 | 0.8473 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0058 | 0.2815 | 0.2815 |
Echinococcus multilocularis | insulin receptor | 0.0058 | 0.2815 | 0.2815 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0154 | 0.8473 | 1 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0057 | 0.28 | 0.3305 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.5055 | 0.5055 |
Toxoplasma gondii | sedoheptulose-1,7-bisphosphatase | 0.0057 | 0.28 | 0.3305 |
Schistosoma mansoni | tyrosine kinase | 0.0058 | 0.2815 | 0.2815 |
Echinococcus granulosus | epidermal growth factor receptor | 0.018 | 1 | 1 |
Plasmodium falciparum | ABC transporter G family member 2 | 0.001 | 0 | 0.5 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0154 | 0.8473 | 0.7875 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.001 | 0 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.5055 | 0.5055 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.