Detailed information for compound 52509

Basic information

Technical information
  • TDR Targets ID: 52509
  • Name: N-methyl-N-[(4-phenylphenyl)methyl]-4-(thiomo rpholin-4-ylmethyl)aniline
  • MW: 388.568 | Formula: C25H28N2S
  • H donors: 0 H acceptors: 0 LogP: 5.42 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(c1ccc(cc1)CN1CCSCC1)Cc1ccc(cc1)c1ccccc1
  • InChi: 1S/C25H28N2S/c1-26(19-21-7-11-24(12-8-21)23-5-3-2-4-6-23)25-13-9-22(10-14-25)20-27-15-17-28-18-16-27/h2-14H,15-20H2,1H3
  • InChiKey: VAZZEBRYQVYRNZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-methyl-N-[(4-phenylphenyl)methyl]-4-(thiomorpholinomethyl)aniline
  • methyl-(4-phenylbenzyl)-[4-(thiomorpholinomethyl)phenyl]amine
  • AIDS-080538
  • AIDS080538
  • Methyl[(4-phenylphenyl)methyl][4-(1,4-thiazaperhydroin-4-ylmethyl)phenyl]amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis 0.0028 0.0077 0.0077
Plasmodium falciparum amino acid transporter, putative 0.0141 0.0549 0.6337
Onchocerca volvulus 0.0137 0.0533 0.1555
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis musashi 0.0027 0.0072 0.0072
Echinococcus granulosus expressed conserved protein 0.0182 0.072 0.1267
Mycobacterium ulcerans carboxylesterase, LipT 0.0137 0.0533 0.2098
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0037 0.0115 0.0394
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0046 0.0061
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0046 0.0081
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0001 0.0001
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0000003442 0.0000011812
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0017 0.003 0.0018
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0046 0.0061
Brugia malayi multidrug resistance protein 3 0.0053 0.0181 0.0241
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0.0000003442 0.0000011812
Echinococcus granulosus arachidonate 5 lipoxygenase 0.1298 0.5379 0.9464
Loa Loa (eye worm) hypothetical protein 0.0044 0.0142 0.0188
Trichomonas vaginalis ABC transporter, putative 0.0053 0.0181 0.0623
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0009 0.0009
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0255 0.1027 0.1363
Mycobacterium tuberculosis Carboxylesterase LipT 0.0137 0.0533 0.2175
Onchocerca volvulus 0.0048 0.016 0.0467
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0012 0.0009 0.0012
Mycobacterium ulcerans oxidoreductase 0.0255 0.1027 0.4039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis Polycystic kidney disease protein 0.0217 0.0866 0.0866
Trichomonas vaginalis aldo-keto reductase, putative 0.0255 0.1027 0.3523
Brugia malayi hypothetical protein 0.0036 0.011 0.0146
Brugia malayi WGR domain containing protein 0.001 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0002
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0141 0.0549 0.5345
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0028 0.0077 0.0102
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0141 0.0549 0.0965
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0042 0.0166
Leishmania major p-glycoprotein e 0.0017 0.003 0.0006
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0001 0.0001
Echinococcus granulosus GPCR family 2 0.0031 0.009 0.0158
Brugia malayi nuclear hormone receptor 0.001 0.0001 0.0001
Plasmodium falciparum ABC transporter B family member 5, putative 0.0017 0.003 0.0345
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0046 0.0087
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0001 0.0001
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0255 0.1027 0.1806
Entamoeba histolytica P-glycoprotein-2 0.0053 0.0181 0.1767
Loa Loa (eye worm) hypothetical protein 0.0137 0.0533 0.0708
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0061
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0012 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0036 0.011 0.1068
Schistosoma mansoni neuropeptide receptor 0.0012 0.0009 0.0016
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0253 0.2465
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0017 0.003 0.0291
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0255 0.1027 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0014 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0028 0.0077 0.0218
Leishmania major UDP-galactopyranose mutase 0.0044 0.0142 0.0155
Brugia malayi AKH receptor 0.0012 0.0009 0.0012
Mycobacterium ulcerans oxidoreductase 0.0023 0.0055 0.0216
Schistosoma mansoni nuclear receptor 0.001 0.0001 0.0001
Entamoeba histolytica P-glycoprotein-2, putative 0.0053 0.0181 0.1767
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Leishmania major C-8 sterol isomerase-like protein 0.1814 0.7535 1
Entamoeba histolytica P-glycoprotein 6, putative 0.0017 0.003 0.0291
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0044 0.0142 0.1637
Loa Loa (eye worm) oxidoreductase 0.0255 0.1027 0.1363
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0023 0.0055 0.0039
Schistosoma mansoni amine GPCR 0.0012 0.0009 0.0016
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0046 0.0081
Schistosoma mansoni tyrosine kinase 0.0157 0.0617 0.1085
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0001 0.0001
Entamoeba histolytica ATP-binding cassette protein, putative 0.0017 0.003 0.0291
Leishmania major prostaglandin f synthase, putative 0.0255 0.1027 0.1333
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Treponema pallidum quinoline 2-oxidoreductase 0.0112 0.0429 0.1251
Plasmodium vivax multidrug resistance protein 1, putative 0.0053 0.0181 0.2095
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0044 0.0142 0.0188
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0149 0.0198
Loa Loa (eye worm) ABC transporter 0.0017 0.003 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium ulcerans electron transfer protein 0.0023 0.0055 0.0216
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0074 0.0269 0.0923
Loa Loa (eye worm) tnks protein 0.0062 0.0221 0.0293
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0012 0.0009 0.0012
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0141 0.0549 0.0965
Schistosoma mansoni tyrosine kinase 0.0095 0.0355 0.0624
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0046 0.0027
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0017 0.003 0.0291
Echinococcus granulosus lysine specific histone demethylase 1A 0.0044 0.0142 0.0249
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0046 0.0181
Echinococcus multilocularis lamin 0.0027 0.0072 0.0072
Entamoeba histolytica hypothetical protein 0.0036 0.011 0.1068
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0141 0.0549 0.0728
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0255 0.1027 0.1333
Schistosoma mansoni wnt-5 0.0014 0.0016 0.0029
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0149 0.0198
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0074 0.0269 0.2619
Loa Loa (eye worm) hypothetical protein 0.0102 0.0385 0.0511
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0017 0.003 0.0291
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0046 0.0135
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0255 0.1027 0.3523
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0044 0.0142 0.0558
Brugia malayi steroid hormone receptor 0.0021 0.0046 0.0061
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0074 0.0269 0.0324
Schistosoma mansoni multidrug resistance protein 0.0017 0.003 0.0053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0009 0.0016
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0022
Onchocerca volvulus 0.0049 0.0165 0.0481
Echinococcus multilocularis acetylcholinesterase 0.0813 0.3353 0.3353
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0141 0.0549 0.0965
Loa Loa (eye worm) wnt-4 protein 0.0014 0.0016 0.0022
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.0046 0.0448
Echinococcus multilocularis protein Wnt 1 0.0014 0.0016 0.0016
Onchocerca volvulus 0.0053 0.0181 0.0529
Schistosoma mansoni hypothetical protein 0.0012 0.0009 0.0016
Trypanosoma brucei poly(adp-ribose) polymerase 0.001 0.0001 0.0001
Toxoplasma gondii ferredoxin, putative 0.0023 0.0055 0.0535
Mycobacterium ulcerans dehydrogenase 0.0044 0.0142 0.0558
Schistosoma mansoni BC026374 protein (S09 family) 0.0137 0.0533 0.0938
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Echinococcus granulosus protein Wnt 1 0.0014 0.0016 0.0029
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0046 0.0046
Brugia malayi ecdysone receptor 0.001 0.0001 0.0001
Loa Loa (eye worm) oxidoreductase 0.0021 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0141 0.0549 0.0728
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0046 0.0087
Schistosoma mansoni tyrosine kinase 0.0095 0.0355 0.0624
Trichomonas vaginalis aldo-keto reductase, putative 0.0074 0.0269 0.0923
Onchocerca volvulus 0.0012 0.0009 0.0026
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0028 0.0077 0.0301
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0046 0.0181
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0028 0.0077 0.0218
Onchocerca volvulus 0.0141 0.0549 0.16
Onchocerca volvulus Tankyrase homolog 0.0061 0.0216 0.0631
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0707 0.2914 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0224 0.0224
Echinococcus multilocularis multidrug resistance associated protein 7 0.0017 0.003 0.003
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0023 0.0055 0.016
Echinococcus granulosus RUN 0.0217 0.0866 0.1523
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0028 0.0077 0.0301
Echinococcus granulosus multidrug resistance protein 1 0.0053 0.0181 0.0319
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0034 0.0036
Trichomonas vaginalis aldo/keto reductase, putative 0.0255 0.1027 0.3523
Brugia malayi Wnt-4 protein precursor 0.0014 0.0016 0.0022
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0072 0.0095
Schistosoma mansoni survival motor neuron protein 0.0048 0.016 0.0281
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0061
Onchocerca volvulus 0.0012 0.0009 0.0026
Plasmodium falciparum LCCL domain-containing protein 0.0217 0.0866 1
Brugia malayi wnt family protein 0.0014 0.0016 0.0022
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0141 0.0549 0.0728
Treponema pallidum sodium- and chloride- dependent transporter 0.0831 0.3429 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0053 0.0181 0.0623
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0009 0.0009
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0046 0.0046
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.001 0.0001 0.0001
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0009 0.0016
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0023 0.0055 0.0055
Brugia malayi ABC transporter 0.0017 0.003 0.004
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0017 0.003 0.004
Onchocerca volvulus 0.0255 0.1027 0.2994
Trichomonas vaginalis ABC transporter, putative 0.0053 0.0181 0.0623
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus granulosus cytochrome P450 2K1 0.0028 0.0077 0.0135
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.008 0.0295 0.0518
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0026 0.0026
Brugia malayi AMP-binding enzyme family protein 0.007 0.0253 0.0336
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0083 0.0307 0.0408
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0017 0.003 0.0102
Brugia malayi Patched protein homolog 1 0.0012 0.0009 0.0012
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Brugia malayi Carboxylesterase family protein 0.0137 0.0533 0.0708
Schistosoma mansoni hypothetical protein 0.0031 0.009 0.0158
Brugia malayi Cytochrome P450 family protein 0.0045 0.0149 0.0198
Leishmania major ABC-thiol transporter 0.0017 0.003 0.0006
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0255 0.1027 0.1806
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0046 0.0061
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0046 0.0181
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0137 0.0533 0.0938
Echinococcus granulosus Niemann Pick C1 protein 0.0277 0.1116 0.1964
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0618 0.2542 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0046 0.0081
Schistosoma mansoni acetylcholinesterase 0.0137 0.0533 0.0938
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0001 0.0001
Schistosoma mansoni multidrug resistance protein 0.0053 0.0181 0.0319
Treponema pallidum hypothetical protein 0.0095 0.0355 0.1036
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0255 0.1027 0.1806
Toxoplasma gondii cytochrome p450 superfamily protein 0.0028 0.0077 0.0746
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0141 0.0549 0.0728
Plasmodium vivax hypothetical protein, conserved 0.0141 0.0549 0.6337
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0046 0.0061
Schistosoma mansoni cytochrome P450 0.0028 0.0077 0.0135
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.002 0.0042 0.0411
Entamoeba histolytica hypothetical protein 0.0017 0.003 0.0291
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Onchocerca volvulus 0.0012 0.0009 0.0026
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0239 0.0957 0.3991
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0009 0.0016
Echinococcus granulosus Protein Wnt-04 0.0014 0.0016 0.0029
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0009 0.0016
Schistosoma mansoni neuropeptide receptor 0.0012 0.0009 0.0016
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0255 0.1027 0.1363
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0065 0.0749
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.007 0.0253 0.0996
Loa Loa (eye worm) hypothetical protein 0.0137 0.0533 0.0708
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0161 0.0283
Echinococcus multilocularis serotonin receptor 0.0012 0.0009 0.0009
Echinococcus multilocularis protein patched 0.0083 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.007 0.0253 0.0336
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0255 0.1027 0.1027
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0028 0.0077 0.0301
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0028 0.0077 0.0301
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0053 0.0181 0.0623
Schistosoma mansoni wnt related 0.0014 0.0016 0.0029
Schistosoma mansoni sodium/chloride dependent transporter 0.0831 0.3429 0.6032
Schistosoma mansoni amine GPCR 0.0012 0.0009 0.0016
Onchocerca volvulus 0.0012 0.0009 0.0026
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0137 0.0533 0.0708
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0012 0.0009 0.0026
Entamoeba histolytica ATP-binding cassette protein, putative 0.0017 0.003 0.0291
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0028 0.0077 0.0301
Echinococcus granulosus neuropeptide receptor 0.0012 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0035
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0028 0.0077 0.0301
Echinococcus granulosus para nitrobenzyl esterase 0.0137 0.0533 0.0938
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.001 0.0001 0.0007
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0009 0.0016
Echinococcus multilocularis orexin receptor type 2 0.0012 0.0009 0.0009
Brugia malayi hypothetical protein 0.0141 0.0549 0.0728
Onchocerca volvulus 0.0012 0.0009 0.0026
Brugia malayi conserved hypotetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis neuroligin 0.0137 0.0533 0.0533
Schistosoma mansoni poly [ADP-ribose] polymerase 0.001 0.0001 0.0001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis geminin 0.0516 0.2113 0.2113
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0009 0.0009
Loa Loa (eye worm) DR-78 0.001 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0028 0.0077 0.0301
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0046 0.0181
Trypanosoma cruzi ABC transporter, putative 0.002 0.0042 0.0056
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0009 0.0012
Onchocerca volvulus 0.0044 0.0142 0.0413
Toxoplasma gondii hypothetical protein 0.0141 0.0549 0.5345
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0067 0.0241 0.0319
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0028 0.0077 0.0218
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0046 0.0448
Brugia malayi SWIRM domain containing protein 0.0044 0.0142 0.0188
Chlamydia trachomatis protoporphyrinogen oxidase 0.0044 0.0142 0.2583
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0197 0.0782 0.1375
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0009 0.0009
Leishmania major hypothetical protein, conserved 0.0023 0.0055 0.0039
Plasmodium vivax aldehyde reductase, putative 0.0074 0.0269 0.3105
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0023 0.0055 0.0039
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Echinococcus granulosus multidrug resistance associated protein 1 0.0017 0.003 0.0053
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0053 0.0181 0.3306
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Trichomonas vaginalis aldo-keto reductase, putative 0.0255 0.1027 0.3523
Schistosoma mansoni neuropeptide f receptor 76f 0.0012 0.0009 0.0016
Onchocerca volvulus 0.0012 0.0009 0.0026
Schistosoma mansoni wnt related 0.0014 0.0016 0.0029
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0017 0.003 0.0291
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0017 0.003 0.004
Echinococcus multilocularis ATP binding cassette sub family B 0.0017 0.003 0.003
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0053 0.0181 0.0623
Schistosoma mansoni intermediate filament proteins 0.0027 0.0072 0.0126
Echinococcus multilocularis aldo keto reductase 0.0255 0.1027 0.1027
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0012 0.0009 0.0016
Trypanosoma cruzi aldo-keto reductase 0.0255 0.1027 0.1363
Brugia malayi Cytochrome P450 family protein 0.0066 0.0235 0.0312
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0012
Brugia malayi Melatonin receptor type 1A 0.0012 0.0009 0.0012
Brugia malayi Carboxylesterase family protein 0.0813 0.3353 0.445
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0052 0.0179 0.0657
Loa Loa (eye worm) hypothetical protein 0.0052 0.0179 0.0238
Brugia malayi cyclic AMP-response element binding protein 1 gamma 1, putative 0.0211 0.0841 0.1116
Echinococcus granulosus intermediate filament protein 0.0027 0.0072 0.0126
Echinococcus granulosus lysine specific histone demethylase 1A 0.0044 0.0142 0.0249
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0053 0.0181 0.0181
Loa Loa (eye worm) carboxylesterase 0.0813 0.3353 0.445
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0026 0.0045
Echinococcus multilocularis wnt family member wnt11 2 0.0014 0.0016 0.0016
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0023 0.0055 0.0073
Echinococcus multilocularis protein dispatched 1 0.0095 0.0356 0.0356
Trichomonas vaginalis Ferredoxin 7 0.0023 0.0055 0.0188
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0135 0.0524 0.2134
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0255 0.1027 0.1027
Plasmodium falciparum multidrug resistance protein 1 0.0053 0.0181 0.2095
Schistosoma mansoni tyrosine kinase 0.0157 0.0617 0.1085
Trypanosoma brucei C-8 sterol isomerase, putative 0.1814 0.7535 1
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0141 0.0549 0.0728
Loa Loa (eye worm) hypothetical protein 0.0044 0.0142 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0307 0.1054
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0017 0.003 0.0345
Brugia malayi nuclear receptor NHR-88 0.0021 0.0046 0.0061
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0141 0.0549 0.0549
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0026 0.0034
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.009 0.0119
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0028 0.0077 0.0301
Trichomonas vaginalis aldo-keto reductase, putative 0.0255 0.1027 0.3523
Trichomonas vaginalis aldo-keto reductase, putative 0.0255 0.1027 0.3523
Echinococcus granulosus peptide allatostatin:somatostatin 0.0012 0.0009 0.0016
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0028 0.0077 0.0301
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0135 0.0524 0.2061
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0042 0.0074
Plasmodium vivax multidrug resistance protein 2, putative 0.0017 0.003 0.0345
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0074 0.0269 0.3105
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0046 0.0181
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0009 0.0009
Leishmania major pentamidine resistance protein 1 0.0017 0.003 0.0006
Entamoeba histolytica aldose reductase, putative 0.0255 0.1027 1
Brugia malayi hypothetical protein 0.001 0.0001 0.0001
Entamoeba histolytica P-glyco protein 6, putative 0.0053 0.0181 0.1767
Schistosoma mansoni rab6-interacting 0.0217 0.0866 0.1523
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0052 0.0179 0.3262
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0001 0.0001
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0012 0.0009 0.0009
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Brugia malayi hypothetical protein 0.0217 0.0866 0.1149
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0017 0.003 0.544
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0046 0.0081
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.1298 0.5379 0.5379
Trichomonas vaginalis ABC transporter, putative 0.0053 0.0181 0.0623
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0046 0.0061
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0255 0.1027 0.1363
Echinococcus multilocularis ferredoxin adrenodoxin 0.0023 0.0055 0.0055
Plasmodium vivax multidomain scavenger receptor, putative 0.0217 0.0866 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis Niemann Pick C1 protein 0.0194 0.0769 0.0769
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0831 0.3429 0.455
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0023 0.0055 0.0216
Echinococcus granulosus tumor protein p63 0.0336 0.1361 0.2395
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis aldehyde reductase 0.0181 0.0718 0.0718
Trypanosoma cruzi aldo/keto reductase, putative 0.0255 0.1027 0.1363
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0046 0.0081
Schistosoma mansoni microtubule-associated protein tau 0.1371 0.5684 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0012 0.0009 0.0016
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0006 0.0006
Plasmodium vivax ABC transporter B family member 4, putative 0.0017 0.003 0.0345
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Brugia malayi wnt family protein 0.0014 0.0016 0.0022
Onchocerca volvulus 0.0137 0.0533 0.1555
Onchocerca volvulus 0.0217 0.0866 0.2525
Loa Loa (eye worm) hypothetical protein 0.0217 0.0866 0.1149
Schistosoma mansoni hypothetical protein 0.0051 0.0174 0.0307
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0009 0.0016
Echinococcus granulosus lipoxygenase domain containing protein 0.0217 0.0866 0.1523
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0052 0.0179 0.0704
Schistosoma mansoni multidrug resistance protein 0.0053 0.0181 0.0319
Schistosoma mansoni sodium/chloride dependent transporter 0.0141 0.0549 0.0965
Entamoeba histolytica zinc finger protein, putative 0.001 0.0001 0.0007
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0028 0.0077 0.0218
Echinococcus multilocularis neuropeptide receptor A26 0.0012 0.0009 0.0009
Echinococcus granulosus epidermal growth factor receptor 0.0296 0.1196 0.2103
Echinococcus multilocularis aldo keto reductase 0.0255 0.1027 0.1027
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0023 0.0055 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0046 0.0046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0001 0.0001
Plasmodium falciparum aldo-keto reductase, putative 0.0074 0.0269 0.3105
Brugia malayi hypothetical protein 0.0235 0.0941 0.1248
Echinococcus granulosus voltage gated potassium channel subunit 0.0074 0.0269 0.0473
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0255 0.1027 0.1806
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0046 0.0448
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0149 0.0198
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0046 0.0061
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0001 0.0001
Onchocerca volvulus 0.0255 0.1027 0.2994
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0046 0.0081
Brugia malayi AMP-binding enzyme family protein 0.007 0.0253 0.0336
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0017 0.003 0.0117
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0017 0.003 0.0117
Entamoeba histolytica aldose reductase, putative 0.0255 0.1027 1
Echinococcus granulosus protein Wnt 2 0.0014 0.0016 0.0029
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0141 0.0549 0.0965
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0141 0.0549 0.0549
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0022
Echinococcus granulosus neuroligin 0.0137 0.0533 0.0938
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0017 0.003 0.0291
Echinococcus granulosus lamin 0.0027 0.0072 0.0126
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0053 0.0181 0.0319
Mycobacterium tuberculosis Possible oxygenase 0.0023 0.0055 0.0125
Trypanosoma brucei ATP-binding cassette protein, putative 0.002 0.0042 0.0056
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0017 0.003 0.004
Plasmodium falciparum acyl-CoA synthetase 0.0052 0.0179 0.2067
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0046 0.0158
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0044 0.0142 0.1381
Entamoeba histolytica P-glycoprotein 5, putative 0.0053 0.0181 0.1767
Echinococcus granulosus zinc finger transcription factor gli2 0.0308 0.1247 0.2194
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus granulosus ATP binding cassette sub family B 0.0017 0.003 0.0053
Mycobacterium ulcerans hypothetical protein 0.007 0.0253 0.0996
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.0046 0.0448
Echinococcus multilocularis multidrug resistance protein 1 0.0037 0.0115 0.0115
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0012 0.0009 0.0016
Echinococcus multilocularis sterol regulatory element binding protein 0.0083 0.0307 0.0307
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0046 0.0081
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0028 0.0077 0.0301
Onchocerca volvulus 0.0141 0.0549 0.16
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0006 0.001
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0253 0.0303
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0028 0.0077 0.0218
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0007
Mycobacterium tuberculosis Probable oxidoreductase 0.0255 0.1027 0.4288
Mycobacterium ulcerans monoamine oxidase 0.0044 0.0142 0.0558
Trypanosoma brucei electron transfer protein, putative 0.0023 0.0055 0.0073
Schistosoma mansoni biogenic amine receptor 0.0012 0.0009 0.0016
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0009 0.0016
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0046 0.0087
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0012 0.0009 0.0016
Schistosoma mansoni poly [ADP-ribose] polymerase 0.001 0.0001 0.0001
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0016 0.0027 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0046 0.0061
Brugia malayi Patched related family protein 4 0.0012 0.0009 0.0012
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0012 0.0009 0.0009
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0009 0.0016
Brugia malayi sulfakinin receptor protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0017 0.003 0.004
Schistosoma mansoni biogenic amine receptor 0.0012 0.0009 0.0016
Brugia malayi Wnt-2 protein precursor 0.0014 0.0016 0.0022
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0001 0.0002
Onchocerca volvulus 0.0137 0.0533 0.1555
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0053 0.0181 0.0623
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.0095
Schistosoma mansoni adenoreceptor 0.0012 0.0009 0.0016
Schistosoma mansoni lipoxygenase 0.0907 0.3749 0.6595
Schistosoma mansoni hypothetical protein 0.008 0.0295 0.0518
Echinococcus multilocularis lamin dm0 0.0027 0.0072 0.0072
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis carboxylesterase 5A 0.0813 0.3353 0.3353
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Onchocerca volvulus 0.0021 0.0046 0.0135
Onchocerca volvulus 0.007 0.0253 0.0738
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.016 0.0212
Loa Loa (eye worm) solute carrier family 6 member 4 0.0831 0.3429 0.455
Trichomonas vaginalis spcc417.12 protein, putative 0.0137 0.0533 0.183
Brugia malayi Carboxylesterase family protein 0.0137 0.0533 0.0708
Echinococcus granulosus survival motor neuron protein 1 0.0235 0.0941 0.1655
Toxoplasma gondii hypothetical protein 0.0141 0.0549 0.5345
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0253 0.0996
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0141 0.0549 0.0965
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.007 0.0253 0.0974
Echinococcus granulosus sterol regulatory element binding protein 0.0083 0.0307 0.054
Trypanosoma brucei ABC transporter, putative 0.002 0.0042 0.0056
Schistosoma mansoni lamin 0.0027 0.0072 0.0126
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Brugia malayi Cytochrome P450 family protein 0.0028 0.0077 0.0102
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0000003442 0.0000011812
Schistosoma mansoni neuropeptide receptor 0.0012 0.0009 0.0016
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0255 0.1027 0.1027
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0007 0.0012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0009 0.0009
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0095 0.0355 0.0355
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0026 0.0026
Trichomonas vaginalis Ferredoxin 6 0.0023 0.0055 0.0188
Giardia lamblia Aldose reductase 0.0255 0.1027 1
Mycobacterium leprae Possible oxidoreductase 0.0074 0.0269 0.2619
Onchocerca volvulus 0.0012 0.0009 0.0026
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0046 0.0046
Giardia lamblia Multidrug resistance-associated protein 1 0.0017 0.003 0.0291
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0006 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0009 0.0016
Echinococcus granulosus geminin 0.0516 0.2113 0.3717
Trypanosoma brucei p-glycoprotein 0.0017 0.003 0.004
Trichomonas vaginalis aldo-keto reductase, putative 0.0255 0.1027 0.3523
Loa Loa (eye worm) hypothetical protein 0.0255 0.1027 0.1363
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0046 0.0158
Brugia malayi putative neuropeptide receptor 0.0012 0.0009 0.0012
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0046 0.0181
Trichomonas vaginalis Ferredoxin 3 0.0023 0.0055 0.0188
Schistosoma mansoni adrenodoxin 0.0023 0.0055 0.0097
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0028 0.0077 0.0218
Giardia lamblia Hypothetical protein 0.0016 0.0027 0.0258
Brugia malayi Doublecortin family protein 0.0217 0.0866 0.1149
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0009 0.0009
Echinococcus granulosus Protein patched homolog 1 0.0083 0.0307 0.054
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.009 0.0158
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.009 0.0158
Schistosoma mansoni amine oxidase 0.0044 0.0142 0.0249
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0061
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0137 0.0533 0.0938
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0009 0.0009
Echinococcus granulosus lipoxygenase domain containing protein 0.0217 0.0866 0.1523
Loa Loa (eye worm) multidrug resistance protein 3 0.0053 0.0181 0.0241
Trypanosoma cruzi multidrug resistance protein E, putative 0.0017 0.003 0.004
Echinococcus multilocularis expressed conserved protein 0.0182 0.072 0.072
Echinococcus granulosus orexin receptor type 2 0.0012 0.0009 0.0016
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0028 0.0077 0.0301
Echinococcus granulosus aldehyde reductase 0.0181 0.0718 0.1263
Brugia malayi neuropeptide F receptor 0.0012 0.0009 0.0012
Echinococcus granulosus acetylcholinesterase 0.0813 0.3353 0.59
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0061
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0028 0.0077 0.0218
Loa Loa (eye worm) Wnt2 protein 0.0014 0.0016 0.0022
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0026 0.0034
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0001 0.0001
Trichomonas vaginalis aldo-keto reductase, putative 0.0255 0.1027 0.3523
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0334 0.1353 0.5322
Echinococcus multilocularis 0.0044 0.0142 0.0142
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0009 0.0009
Echinococcus multilocularis voltage gated potassium channel subunit 0.0074 0.0269 0.0269
Schistosoma mansoni amine GPCR 0.0012 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0044 0.0142 0.0188
Loa Loa (eye worm) hypothetical protein 0.0137 0.0533 0.0708
Schistosoma mansoni hypothetical protein 0.0031 0.009 0.0158
Mycobacterium ulcerans oxidoreductase 0.0023 0.0055 0.0216
Schistosoma mansoni opsin-like receptor 0.0012 0.0009 0.0016
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0023 0.0055 0.0535
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0046 0.0027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium ulcerans hypothetical protein 0.0115 0.044 0.1732
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0161 0.0214
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Brugia malayi hypothetical protein 0.0217 0.0866 0.1149
Echinococcus granulosus epidermal growth factor receptor 0.0159 0.0624 0.1097
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.002 0.0042 0.0074
Brugia malayi Serotonin receptor 0.0012 0.0009 0.0012
Echinococcus multilocularis zinc finger transcription factor gli2 0.0308 0.1247 0.1247
Echinococcus granulosus multidrug resistance associated protein 7 0.0017 0.003 0.0053
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0255 0.1027 0.1027
Brugia malayi G-protein coupled receptor 0.0012 0.0009 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0009 0.0016
Entamoeba histolytica ABC transporter, putative 0.002 0.0042 0.0411
Brugia malayi neuropeptide F receptor 0.0012 0.0009 0.0012
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0012 0.0009 0.0012
Onchocerca volvulus 0.0012 0.0009 0.0026
Echinococcus granulosus acetylcholinesterase 0.0813 0.3353 0.59
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.0235 0.0312
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0009 0.0016
Brugia malayi hypothetical protein 0.0017 0.003 0.004
Trichomonas vaginalis abcb9, putative 0.0053 0.0181 0.0623
Trypanosoma cruzi adrenodoxin precursor, putative 0.0023 0.0055 0.0073
Echinococcus multilocularis BC026374 protein (S09 family) 0.0137 0.0533 0.0533
Chlamydia trachomatis ferredoxin 0.0023 0.0055 0.1
Brugia malayi G protein-coupled receptor 0.0012 0.0009 0.0012
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0028 0.0077 0.0301
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus granulosus ATP binding cassette sub family B 0.0016 0.0027 0.0047
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0028 0.0077 0.0218
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0161 0.0161
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0012 0.0009 0.0012
Onchocerca volvulus 0.001 0.0001 0.0002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0001 0.0002
Mycobacterium leprae putative cytochrome p450 0.0028 0.0077 0.0746
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.007 0.0253 0.0336
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0009 0.0016
Loa Loa (eye worm) acetylcholinesterase 1 0.0813 0.3353 0.445
Toxoplasma gondii patched family protein 0.0012 0.0009 0.0087
Trichomonas vaginalis aldo-keto reductase, putative 0.0255 0.1027 0.3523
Mycobacterium tuberculosis Conserved protein 0.0074 0.0269 0.1042
Echinococcus granulosus poly ADP ribose polymerase 1 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0052 0.0179 0.0238
Brugia malayi nuclear hormone receptor 0.0021 0.0046 0.0061
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0137 0.0533 0.2175
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0028 0.0077 0.0218
Plasmodium falciparum ABC transporter B family member 3, putative 0.0017 0.003 0.0345
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0055 0.0125
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Onchocerca volvulus Protein patched homolog 0.0012 0.0009 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0061
Brugia malayi Carboxylesterase family protein 0.0137 0.0533 0.0708
Schistosoma mansoni loxhd1 0.0217 0.0866 0.1523
Echinococcus multilocularis multidrug resistance protein 1 0.0053 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0217 0.0866 0.1149
Mycobacterium ulcerans electron transfer protein FdxB 0.0023 0.0055 0.0216
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0053 0.0181 0.0181
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0009 0.0016
Onchocerca volvulus 0.0255 0.1027 0.2994
Plasmodium falciparum ABC transporter G family member 2 0.002 0.0042 0.0487
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0012
Brugia malayi cytochrome P450 0.0028 0.0077 0.0102
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0065 0.0749
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0046 0.0081
Schistosoma mansoni lamin 0.0027 0.0072 0.0126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0009 0.0009
Echinococcus granulosus Polycystic kidney disease protein 0.0217 0.0866 0.1523
Entamoeba histolytica hypothetical protein 0.0036 0.011 0.1068
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0149 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0002
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0053 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0052 0.0178 0.0236
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0044 0.0142 0.1637
Schistosoma mansoni hypothetical protein 0.0067 0.0241 0.0423
Loa Loa (eye worm) hypothetical protein 0.0052 0.0176 0.0233
Loa Loa (eye worm) hypothetical protein 0.0831 0.3429 0.455
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0001 0.0001
Onchocerca volvulus 0.001 0.0001 0.0002
Trypanosoma cruzi aldo/keto reductase, putative 0.0074 0.0269 0.0357
Echinococcus multilocularis ATP binding cassette sub family B 0.0017 0.003 0.003
Echinococcus multilocularis sodium and chloride dependent glycine 0.0141 0.0549 0.0549
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0001 0.0001
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0046 0.0087
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0053 0.0181 0.0319
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Brugia malayi Furin-like cysteine rich region family protein 0.0296 0.1196 0.1587
Schistosoma mansoni lipoxygenase 0.1298 0.5379 0.9464
Trypanosoma cruzi adrenodoxin precursor, putative 0.0023 0.0055 0.0073
Brugia malayi G-protein coupled receptor 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Plasmodium falciparum protoporphyrinogen oxidase 0.0044 0.0142 0.1637
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0065 0.0749
Echinococcus multilocularis G-protein coupled receptor, putative 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0269 0.0923
Echinococcus multilocularis dro:myosuppressin receptor 0.0012 0.0009 0.0009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0253 0.0974
Onchocerca volvulus 0.0023 0.0055 0.016
Echinococcus multilocularis tumor protein p63 0.0336 0.1361 0.1361
Schistosoma mansoni adrenodoxin 0.0023 0.0055 0.0097
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0042 0.0074
Onchocerca volvulus 0.0021 0.0046 0.0134
Schistosoma mansoni hypothetical protein 0.0031 0.009 0.0158
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0053 0.0181 0.0623
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0046 0.0061
Schistosoma mansoni hypothetical protein 0.0011 0.0007 0.0012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0009 0.0009
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0046 0.0087
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.037 0.0492
Brugia malayi Cytochrome P450 family protein 0.0045 0.0149 0.0198
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0023 0.0055 0.0073
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0046 0.0046
Echinococcus multilocularis epidermal growth factor receptor 0.0296 0.1196 0.1196
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0017 0.003 0.0291
Schistosoma mansoni hypothetical protein 0.0048 0.016 0.0281
Loa Loa (eye worm) TK/INSR protein kinase 0.0095 0.0355 0.0471
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0002
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0053 0.0181 0.0623
Brugia malayi Nuclear hormone receptor E75 0.001 0.0001 0.0001
Brugia malayi Dopamine receptor protein 1 0.0012 0.0009 0.0012
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0053 0.0181 0.0623
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0046 0.0181
Loa Loa (eye worm) hypothetical protein 0.0052 0.0179 0.0238
Onchocerca volvulus 0.0012 0.0009 0.0026
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0046 0.0448
Echinococcus multilocularis protein Wnt 2 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0831 0.3429 0.455
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis protoporphyrinogen oxidase 0.0044 0.0142 0.0142
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0255 0.1027 0.1027
Echinococcus granulosus Adrenodoxin mitochondrial 0.0023 0.0055 0.0097
Brugia malayi Myosin head containing protein 0.0012 0.0009 0.0012
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0046 0.0087
Loa Loa (eye worm) norepinephrine transporter 0.0831 0.3429 0.455
Leishmania major hypothetical protein, conserved 0.0025 0.0065 0.0052
Entamoeba histolytica multidrug resistance protein, putative 0.0017 0.003 0.0291
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0028 0.0077 0.0301
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0009 0.0009
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0224 0.0264
Brugia malayi nuclear receptor RXR 0.0011 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0046 0.0081
Echinococcus multilocularis para nitrobenzyl esterase 0.0137 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Trichomonas vaginalis abcb9, putative 0.0053 0.0181 0.0623
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.002 0.0026
Leishmania major cytochrome p450-like protein 0.0028 0.0077 0.0068
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0053 0.0181 0.0623
Brugia malayi ABC transporter transmembrane region family protein 0.0017 0.003 0.004
Onchocerca volvulus 0.0012 0.0009 0.0026
Giardia lamblia Multidrug resistance-associated protein 1 0.0016 0.0027 0.0258
Echinococcus granulosus replication factor c subunit 1 0.001 0.0000003442 0.00000060555
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0046 0.0061
Schistosoma mansoni gliotactin 0.0137 0.0533 0.0938
Echinococcus granulosus G protein coupled receptor 139 0.0012 0.0009 0.0016
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0224 0.0394
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0023 0.0055 0.0216
Brugia malayi follicle stimulating hormone receptor 0.0012 0.0009 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0046 0.0061
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0053 0.0181 0.0319
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0009 0.0016
Schistosoma mansoni sodium/chloride dependent transporter 0.0141 0.0549 0.0965
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0017 0.003 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0028 0.0077 0.0218
Schistosoma mansoni tyrosine kinase 0.0159 0.0624 0.1097
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0007
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0224 0.2181
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0016 0.0027 0.0091
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis GPCR, family 2 0.0031 0.009 0.009
Brugia malayi CHE-14 protein 0.0083 0.0307 0.0408
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0022
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0046 0.0061
Schistosoma mansoni ABC transporter 0.0017 0.003 0.0053
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0141 0.0549 0.0965
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0017 0.003 0.0006
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0000003442 0.0000003442
Brugia malayi Patched related family protein 10 0.0012 0.0009 0.0012
Onchocerca volvulus 0.0012 0.0009 0.0026
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0053 0.0181 0.0623
Onchocerca volvulus 0.0012 0.0009 0.0026
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0053 0.0181 0.0623
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0255 0.1027 0.1027
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.0253 0.2465
Echinococcus granulosus hypothetical protein 0.0012 0.0009 0.0016
Echinococcus multilocularis RUN 0.0217 0.0866 0.0866
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0255 0.1027 0.1333
Loa Loa (eye worm) hypothetical protein 0.0141 0.0549 0.0728
Trichomonas vaginalis aldo-keto reductase, putative 0.0255 0.1027 0.3523
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0009 0.0016
Loa Loa (eye worm) oxidoreductase 0.0255 0.1027 0.1363
Loa Loa (eye worm) hypothetical protein 0.0813 0.3353 0.445
Brugia malayi Nuclear hormone receptor E75 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0137 0.0533 0.0708
Echinococcus multilocularis g-protein coupled receptor 0.0012 0.0009 0.0009
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0012 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0137 0.0533 0.0708
Echinococcus granulosus lamin dm0 0.0027 0.0072 0.0126
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0009 0.0016
Entamoeba histolytica hypothetical protein 0.0036 0.011 0.1068
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0255 0.1027 0.1027
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0046 0.0061
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0017 0.003 0.004
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0009 0.0016
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0813 0.3353 0.59
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0074 0.0269 0.2619
Loa Loa (eye worm) hypothetical protein 0.0017 0.003 0.004
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0053 0.0181 0.0623
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0017 0.003 0.004
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0053 0.0181 0.0623
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0023 0.0055 0.1
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0023 0.0055 0.0125
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0009 0.0016
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0046 0.0181
Brugia malayi AMP-binding enzyme family protein 0.007 0.0253 0.0336
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Trypanosoma brucei prostaglandin f synthase 0.0255 0.1027 0.1363
Schistosoma mansoni multidrug resistance protein 0.0017 0.003 0.0053
Brugia malayi putative neuropeptide receptor NPR1 0.0012 0.0009 0.0012
Schistosoma mansoni tankyrase 0.0068 0.0246 0.0433
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0009 0.0016
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0014 0.0024
Giardia lamblia ABC transporter, putative 0.0017 0.003 0.0291
Schistosoma mansoni nuclear hormone receptor 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0149 0.0198
Schistosoma mansoni smdr1 0.0017 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0046 0.0081
Schistosoma mansoni nuclear hormone receptor 0.001 0.0001 0.0001
Echinococcus granulosus Protein Wnt-5 0.0014 0.0016 0.0029
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0035
Giardia lamblia Multidrug resistance-associated protein 1 0.0017 0.003 0.0291
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0334 0.1353 0.5685
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0028 0.0077 0.0218
Loa Loa (eye worm) oxidoreductase 0.0255 0.1027 0.1363
Brugia malayi hypothetical protein 0.0011 0.0006 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0009 0.0016
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0009 0.0012
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0023 0.0055 0.0073
Trichomonas vaginalis aldo/keto reductase, putative 0.0255 0.1027 0.3523
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0065 0.0632
Toxoplasma gondii patched family protein 0.0012 0.0009 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0253 0.0996
Echinococcus multilocularis Niemann Pick C1 protein 0.0277 0.1116 0.1116
Schistosoma mansoni hypothetical protein 0.0516 0.2113 0.3717
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0072 0.0095
Brugia malayi nuclear receptor NHR-67 0.001 0.0001 0.0001
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0012 0.0009 0.0009
Echinococcus granulosus serotonin transporter 0.0831 0.3429 0.6032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0046 0.0061
Trichomonas vaginalis aldo-keto reductase, putative 0.0074 0.0269 0.0923
Brugia malayi intermediate filament protein 0.0027 0.0072 0.0095
Echinococcus granulosus dro:myosuppressin receptor 0.0012 0.0009 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0002
Brugia malayi hypothetical protein 0.0044 0.0142 0.0188
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0224 0.0881
Brugia malayi Dopamine receptor protein 2 0.0012 0.0009 0.0012
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0253 0.2465
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0053 0.0181 0.0623
Entamoeba histolytica P-glycoprotein-2 0.0053 0.0181 0.1767
Echinococcus granulosus Protein Wnt-11b 0.0014 0.0016 0.0029
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0016 0.0027 0.0004
Echinococcus multilocularis serotonin receptor 0.0012 0.0009 0.0009
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0017 0.003 0.0006
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0052 0.0178 0.0313
Echinococcus granulosus g-protein coupled receptor 0.0012 0.0009 0.0016
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0255 0.1027 0.1806
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0141 0.0549 0.0728
Brugia malayi G protein-coupled receptor F59B2.13 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0831 0.3429 0.455
Loa Loa (eye worm) hypothetical protein 0.0025 0.0065 0.0086
Schistosoma mansoni amine GPCR 0.0012 0.0009 0.0016
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0046 0.0081
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0006 0.0007
Schistosoma mansoni nuclear receptor 0.001 0.0001 0.0001
Echinococcus granulosus poly adp ribose polymerase 2 0.001 0.0001 0.0001
Echinococcus granulosus multidrug resistance protein 1 0.0037 0.0115 0.0202
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0046 0.0087
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0046 0.0061
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0224 0.0394
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0046 0.0181
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0065 0.0086
Echinococcus granulosus ferredoxin 0.0023 0.0055 0.0097
Trypanosoma cruzi UDP-galactopyranose mutase 0.0044 0.0142 0.0188
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0061
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0046 0.0081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0009 0.0016
Leishmania major p-glycoprotein 0.0053 0.0181 0.0207
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0046 0.0061
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0046 0.0081
Echinococcus granulosus g protein coupled receptor 0.0012 0.0009 0.0016
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0028 0.0077 0.0218
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0149 0.0198
Onchocerca volvulus 0.0255 0.1027 0.2994
Brugia malayi protein C24B5.3 0.0012 0.0009 0.0012
Trichomonas vaginalis aldo-keto reductase, putative 0.0255 0.1027 0.3523
Schistosoma mansoni tyrosine kinase 0.0159 0.0624 0.1097
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0046 0.0061
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0053 0.0181 0.0623
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0253 0.0996
Loa Loa (eye worm) hypothetical protein 0.0141 0.0549 0.0728
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0012 0.0009 0.0016
Echinococcus multilocularis sex peptide receptor 0.0012 0.0009 0.0009
Schistosoma mansoni tyrosine kinase 0.0296 0.1196 0.2103
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0017 0.003 0.0018
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0255 0.1027 0.1806
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0161 0.0161
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0074 0.0269 0.0357
Toxoplasma gondii ferodoxin FD 0.0023 0.0055 0.0535
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0053 0.0181 0.0241
Loa Loa (eye worm) ABC transporter 0.0017 0.003 0.004
Brugia malayi nuclear receptor RXR 0.001 0.0001 0.0001
Brugia malayi ABC transporter transmembrane region family protein 0.0016 0.0027 0.0035
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Giardia lamblia [2Fe-2S] ferredoxin 0.0023 0.0055 0.0535
Echinococcus granulosus tankyrase 0.0068 0.0245 0.0432
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0001 0.0001
Echinococcus granulosus insulin receptor 0.0095 0.0355 0.0624
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0009 0.0016
Echinococcus granulosus tachykinin peptides receptor 99D 0.0012 0.0009 0.0016
Echinococcus multilocularis acetylcholinesterase 0.0813 0.3353 0.3353
Trichomonas vaginalis aldo-keto reductase, putative 0.0074 0.0269 0.0923
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0253 0.0303
Loa Loa (eye worm) hypothetical protein 0.0211 0.0841 0.1116
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0042 0.0074
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.009 0.0119
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0012 0.0009 0.0016
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0012 0.0009 0.0012
Schistosoma mansoni myosin xvIII 0.0012 0.0009 0.0016
Schistosoma mansoni patched 1 0.0083 0.0307 0.054
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0046 0.0531
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0049 0.0165 0.0219
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0077 0.0102
Brugia malayi Carboxylesterase family protein 0.0137 0.0533 0.0708
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0017 0.003 0.0006
Mycobacterium tuberculosis Possible oxidoreductase 0.0044 0.0142 0.0497
Onchocerca volvulus 0.0074 0.0269 0.0784
Echinococcus granulosus multidrug resistance protein 1 0.0037 0.0115 0.0202
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0026 0.025
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0065 0.0086
Schistosoma mansoni hypothetical protein 0.008 0.0295 0.0518
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0046 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0055 0.0073
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0026 0.0045
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0255 0.1027 0.1806
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0036 0.011 0.0193
Trypanosoma brucei multidrug resistance protein E 0.0017 0.003 0.004
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0831 0.3429 0.6032
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0017 0.003 0.0291
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0028 0.0077 0.0218
Echinococcus multilocularis ATP binding cassette sub family B 0.0017 0.003 0.003
Leishmania major aldo-keto reductase-like protein 0.0255 0.1027 0.1333
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0017 0.003 0.0006
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0017 0.003 0.004
Loa Loa (eye worm) hypothetical protein 0.0141 0.0549 0.0728
Mycobacterium leprae Conserved hypothetical protein 0.0028 0.0077 0.0746
Loa Loa (eye worm) hypothetical protein 0.0927 0.3832 0.5085
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0044 0.0142 0.0249
Entamoeba histolytica alcohol dehydrogenase, putative 0.0074 0.0269 0.2619
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0017 0.003 0.0117
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0028 0.0077 0.0301
Entamoeba histolytica ATP-binding cassette protein, putative 0.0017 0.003 0.0291
Loa Loa (eye worm) oxidoreductase 0.0255 0.1027 0.1363
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0028 0.0077 0.0068
Echinococcus granulosus 7TM GPCR rhodopsin 0.0012 0.0009 0.0016
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0053 0.0181 0.0667
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0053 0.0181 0.0623
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0009 0.0016
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0046 0.0081
Toxoplasma gondii patched family protein 0.0012 0.0009 0.0087
Leishmania major ferredoxin, 2fe-2s-like protein 0.0023 0.0055 0.0039
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0001 0.0001
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.007 0.0253 0.0996
Echinococcus granulosus aldo keto reductase 0.0255 0.1027 0.1806
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.002 0.0042 0.0022
Echinococcus granulosus multidrug resistance protein 1 0.0053 0.0181 0.0319
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0009 0.0016
Brugia malayi RE15519p 0.0012 0.0009 0.0012
Brugia malayi ABC transporter family protein 0.0017 0.003 0.004
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0046 0.0061
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0141 0.0549 0.0965
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0053 0.0181 0.1767
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0161 0.0283
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0165 0.029
Treponema pallidum hypothetical protein 0.0115 0.044 0.1284
Echinococcus granulosus aldo keto reductase 0.0255 0.1027 0.1806
Echinococcus granulosus hypothetical protein 0.0255 0.1027 0.1806
Echinococcus granulosus allatostatin A receptor 0.0012 0.0009 0.0016
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0009 0.0016
Echinococcus multilocularis epidermal growth factor receptor 0.0159 0.0624 0.0624
Plasmodium falciparum lipid/sterol:H+ symporter 0.0012 0.0009 0.0104
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0042 0.0042
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0017 0.003 0.0117
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0142 0.1637
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0017 0.003 0.0291
Schistosoma mansoni wnt related 0.0014 0.0016 0.0029
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0042 0.0166
Loa Loa (eye worm) TK/EGFR protein kinase 0.0296 0.1196 0.1587
Echinococcus multilocularis neuropeptide FF receptor 2 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0052 0.0179 0.0238
Brugia malayi hypothetical protein 0.0011 0.0006 0.0007
Schistosoma mansoni neuropeptide receptor 0.0012 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Entamoeba histolytica aldose reductase, putative 0.0255 0.1027 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0141 0.0549 0.5345
Echinococcus granulosus ATP binding cassette sub family B 0.0017 0.003 0.0053
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0046 0.0181
Brugia malayi nuclear receptor NHR-88 0.001 0.0001 0.0001
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0053 0.0181 0.0623
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0017 0.003 0.004
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0255 0.1027 0.1806
Brugia malayi ABC transporter family protein 0.0053 0.0181 0.0241
Onchocerca volvulus 0.0012 0.0009 0.0026
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0046 0.0081
Schistosoma mansoni hypothetical protein 0.0012 0.0009 0.0016
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0026 0.0297
Echinococcus granulosus microtubule associated protein 2 0.1371 0.5684 1
Onchocerca volvulus 0.0012 0.0009 0.0026
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0053 0.0181 0.0623
Brugia malayi Dopamine receptor 0.0012 0.0009 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0028 0.0077 0.0218
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Schistosoma mansoni polycystin 1-related 0.0217 0.0866 0.1523
Schistosoma mansoni opsin-like receptor 0.0012 0.0009 0.0016
Brugia malayi hypothetical protein 0.001 0.0001 0.0001
Onchocerca volvulus 0.0255 0.1027 0.2994
Brugia malayi NADH-dependent xylose reductase 0.0074 0.0269 0.0357
Schistosoma mansoni aldo-keto reductase 0.0255 0.1027 0.1806
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.001 0.0001 0.0001
Plasmodium vivax patched family protein, putative 0.0012 0.0009 0.0104
Echinococcus multilocularis survival motor neuron protein 1 0.0235 0.0941 0.0941
Entamoeba histolytica ATP-binding cassette protein, putative 0.0017 0.003 0.0291
Echinococcus granulosus sex peptide receptor 0.0012 0.0009 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0009 0.0009
Onchocerca volvulus 0.0012 0.0009 0.0026
Trypanosoma brucei aldo-keto reductase, putative 0.0255 0.1027 0.1363
Schistosoma mansoni multidrug resistance protein 0.0017 0.003 0.0053
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0072 0.0095
Plasmodium falciparum ABC transporter B family member 7, putative 0.0017 0.003 0.0345
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0022
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0046 0.0081
Onchocerca volvulus 0.0831 0.3429 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.011 0.011
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0017 0.003 0.004
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0141 0.0549 0.0965
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0141 0.0549 0.0728
Schistosoma mansoni hypothetical protein 0.0516 0.2113 0.3717
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0046 0.0081
Schistosoma mansoni neuroligin 3 (S09 family) 0.0137 0.0533 0.0938
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0006 0.001
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.009 0.009
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0009 0.0009
Trichomonas vaginalis aldo-keto reductase, putative 0.0255 0.1027 0.3523
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Brugia malayi Serotonin receptor 0.0012 0.0009 0.0012
Entamoeba histolytica acyl-coA synthetase, putative 0.007 0.0253 0.2465
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0137 0.0533 0.0938
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0009 0.0016
Plasmodium falciparum ABC transporter B family member 4, putative 0.0017 0.003 0.0345
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0141 0.0549 0.0965
Brugia malayi hypothetical protein 0.0137 0.0533 0.0708
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0241 0.0319
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0046 0.0027
Trichomonas vaginalis aldo-keto reductase, putative 0.0255 0.1027 0.3523
Echinococcus multilocularis lipoxygenase domain containing protein 0.0217 0.0866 0.0866
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0009 0.0016
Onchocerca volvulus 0.0137 0.0533 0.1555
Echinococcus granulosus Niemann Pick C1 protein 0.0194 0.0769 0.1353
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0046 0.0061
Echinococcus multilocularis sodium and chloride dependent glycine 0.0141 0.0549 0.0549
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0001 0.0001
Trichomonas vaginalis aldo/keto reductase, putative 0.0255 0.1027 0.3523
Schistosoma mansoni hypothetical protein 0.008 0.0295 0.0518
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0046 0.0081
Echinococcus multilocularis multidrug resistance protein 1 0.0053 0.0181 0.0181
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0053 0.0181 0.0623
Echinococcus granulosus g protein coupled receptor 0.0012 0.0009 0.0016
Echinococcus granulosus carboxylesterase 5A 0.0813 0.3353 0.59
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0141 0.0549 0.0728
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0028 0.0077 0.0301
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0046 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0002
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0028 0.0077 0.0301
Schistosoma mansoni hypothetical protein 0.0016 0.0027 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0046 0.0061
Schistosoma mansoni biogenic amine receptor 0.0012 0.0009 0.0016
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0046 0.0061
Trichomonas vaginalis Ferredoxin 4 0.0023 0.0055 0.0188
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0028 0.0077 0.0301
Trichomonas vaginalis abcb9, putative 0.0053 0.0181 0.0623
Brugia malayi wnt family protein 0.0014 0.0016 0.0022
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0046 0.0087
Loa Loa (eye worm) serotonin transporter b 0.0831 0.3429 0.455
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0167 0.0606
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0012 0.0009 0.0012
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0023 0.0055 0.0125
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.001 0.0001 0.0007
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0000003442 0.00000060555
Echinococcus granulosus serotonin receptor 0.0012 0.0009 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0046 0.0061
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0046 0.0448
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0009 0.0016
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0016 0.0027 0.0091
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0224 0.0394
Plasmodium vivax ABC transporter B family member 7, putative 0.0017 0.003 0.0345
Brugia malayi amine oxidase, flavin-containing family protein 0.0044 0.0142 0.0188
Echinococcus granulosus aldo keto reductase 0.0255 0.1027 0.1806
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0224 0.0881
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0077 0.0102
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1814 0.7535 1
Plasmodium falciparum aldehyde reductase, putative 0.0074 0.0269 0.3105
Schistosoma mansoni multidrug resistance protein 0.0017 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0052 0.0179 0.0238
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0044 0.0142 0.0188
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0046 0.0135
Brugia malayi ABC transporter transmembrane region family protein 0.0017 0.003 0.004
Schistosoma mansoni pol-related 0.0255 0.1027 0.1806
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0.0000003442 0.0000033526
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0137 0.0533 0.183
Schistosoma mansoni aldo-keto reductase 0.0255 0.1027 0.1806
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0046 0.0046
Brugia malayi multidrug resistance related protein 1 0.0017 0.003 0.004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0012 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0235 0.0941 0.1248
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0044 0.0142 0.1637
Echinococcus multilocularis microtubule associated protein 2 0.1371 0.5684 0.5684
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0028 0.0077 0.0218
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0053 0.0181 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0002
Echinococcus multilocularis 0.0092 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus granulosus multidrug resistance protein 1 0.0053 0.0181 0.0319
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0095 0.0355 0.0624
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.021 0.0836 0.3287
Echinococcus multilocularis WNT 0.0014 0.0016 0.0016
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0017 0.003 0.0345
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0046 0.0061
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0618 0.2542 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0141 0.0549 0.0965
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0255 0.1027 0.1363
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.001 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0009 0.0016
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0012 0.0009 0.0016
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.002 0.0042 0.0022
Plasmodium falciparum multidrug resistance protein 2 0.0017 0.003 0.0345
Loa Loa (eye worm) hypothetical protein 0.0137 0.0533 0.0708
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0046 0.0046
Echinococcus multilocularis ATP binding cassette sub family B 0.0017 0.003 0.003
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0026 0.0297
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0046 0.0181
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0575 0.236 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis multidrug resistance associated protein 1 0.0017 0.003 0.003
Leishmania major cytochrome p450-like protein 0.0045 0.0149 0.0165
Echinococcus multilocularis wingless type MMTV integration site family 0.0014 0.0016 0.0016
Entamoeba histolytica P-glycoprotein 5, putative 0.0016 0.0027 0.0258
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0017 0.003 0.004
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0017 0.003 0.0053
Brugia malayi ABC transporter family protein 0.0017 0.003 0.004
Giardia lamblia Aldose reductase 0.0255 0.1027 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0022
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0009 0.0009
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0255 0.1027 0.1027
Entamoeba histolytica P-glycoprotein-5 0.0053 0.0181 0.1767
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0026 0.0034
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Plasmodium vivax ABC transporter B family member 5, putative 0.0017 0.003 0.0345
Onchocerca volvulus 0.0012 0.0009 0.0026
Trypanosoma cruzi ATP-binding cassette protein, putative 0.002 0.0042 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0027 0.0091
Onchocerca volvulus 0.0021 0.0046 0.0134
Echinococcus multilocularis ATP binding cassette sub family B 0.0052 0.0178 0.0178
Plasmodium falciparum transporter, putative 0.0141 0.0549 0.6337
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0194 0.0769 0.7491
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0053 0.0181 0.0207
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0017 0.003 0.0291
Loa Loa (eye worm) hypothetical protein 0.0017 0.0033 0.0043
Toxoplasma gondii ABC transporter, putative 0.0017 0.003 0.0291
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0046 0.0061
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.001 0.0001 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0046 0.0061
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0046 0.0046
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0141 0.0549 0.0728
Echinococcus multilocularis somatostatin receptor 0.0012 0.0009 0.0009
Brugia malayi Protein kinase domain containing protein 0.0095 0.0355 0.0471
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.0253 0.2465
Loa Loa (eye worm) hypothetical protein 0.0053 0.0181 0.0241
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Toxoplasma gondii ABC transporter family protein 0.0017 0.003 0.0291
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0046 0.0181
Loa Loa (eye worm) zinc finger protein 0.0308 0.1247 0.1655
Schistosoma mansoni sodium-dependent amino acid transporter 0.0141 0.0549 0.0965
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0012 0.0009 0.0016
Toxoplasma gondii hypothetical protein 0.0012 0.0009 0.0087
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0046 0.0061
Brugia malayi Latrophilin receptor protein 2 0.0031 0.009 0.0119
Giardia lamblia ABC transporter 0.0019 0.0039 0.0379
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0255 0.1027 0.3523
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.011 0.0193
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0028 0.0077 0.0102
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.002 0.0026
Plasmodium vivax acyl-CoA synthetase, putative 0.0052 0.0179 0.2067
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0017 0.003 0.0117
Echinococcus multilocularis aldo keto reductase 0.0255 0.1027 0.1027
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0026 0.0026
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0053 0.0181 0.0319
Echinococcus multilocularis 0.0017 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Plasmodium falciparum ferredoxin, putative 0.0023 0.0055 0.0634
Echinococcus granulosus g protein coupled receptor 0.0012 0.0009 0.0016
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0053 0.0181 0.0241
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.037 0.0492
Loa Loa (eye worm) hypothetical protein 0.0031 0.009 0.0119
Brugia malayi ecdysteroid receptor 0.0021 0.0046 0.0061
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0001 0.0001
Loa Loa (eye worm) TYRA-2 protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Toxoplasma gondii aldo-keto reductase 0.0074 0.0269 0.2619
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0141 0.0549 0.0965
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0012 0.0009 0.0016
Trypanosoma brucei aldo/keto reductase, putative 0.0074 0.0269 0.0357
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0046 0.0181
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0046 0.0081
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0046 0.0448
Schistosoma mansoni hypothetical protein 0.0031 0.009 0.0158
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0046 0.0181
Loa Loa (eye worm) ABC transporter 0.0017 0.003 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0009 0.0016
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0053 0.0181 0.0623
Echinococcus multilocularis aldo keto reductase 0.0255 0.1027 0.1027
Brugia malayi hypothetical protein 0.0016 0.0028 0.0037
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0017 0.003 0.544
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0016 0.0027 0.0091
Loa Loa (eye worm) melatonin receptor type 1A 0.0012 0.0009 0.0012
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0028 0.0077 0.0301
Onchocerca volvulus 0.0137 0.0533 0.1555
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0141 0.0549 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0046 0.0046
Onchocerca volvulus 0.0012 0.0009 0.0026
Onchocerca volvulus 0.0021 0.0046 0.0134
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0028 0.0077 0.0218
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus granulosus sodium and chloride dependent glycine 0.0141 0.0549 0.0965
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0012 0.0009 0.0009
Schistosoma mansoni smdr2 0.0053 0.0181 0.0319
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0009 0.0016
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0046 0.0061
Echinococcus granulosus sodium and chloride dependent glycine 0.0141 0.0549 0.0965
Loa Loa (eye worm) patched family protein 0.0012 0.0009 0.0012
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0046 0.0087
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus granulosus BC026374 protein S09 family 0.0137 0.0533 0.0938
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0009 0.0016
Echinococcus granulosus fmrfamide receptor 0.0012 0.0009 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0009 0.0016
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0009 0.0009
Brugia malayi WGR domain containing protein 0.001 0.0001 0.0001
Schistosoma mansoni potassium channel beta 0.0074 0.0269 0.0473
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0016
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0016 0.0027 0.0258
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0046 0.0081
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0046 0.0061
Onchocerca volvulus 0.0012 0.0009 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Trichomonas vaginalis taga, putative 0.0053 0.0181 0.0623
Echinococcus multilocularis serotonin transporter 0.0831 0.3429 0.3429
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0159 0.0624 0.1097
Echinococcus multilocularis poly (ADP ribose) polymerase 0.001 0.0001 0.0001
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0044 0.0142 0.0188
Mycobacterium ulcerans hypothetical protein 0.0074 0.0269 0.1058
Entamoeba histolytica hypothetical protein 0.001 0.0001 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0028 0.0077 0.0218
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0239 0.0957 0.3766
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0009 0.0016
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0023 0.0055 0.0634
Plasmodium vivax amine transporter, putative 0.0141 0.0549 0.6337
Schistosoma mansoni amine oxidase 0.0044 0.0142 0.0249
Plasmodium falciparum multidrug resistance-associated protein 1 0.0017 0.003 0.0345
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0023 0.0055 0.0073
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.011 0.0193
Loa Loa (eye worm) carboxylesterase 0.0137 0.0533 0.0708
Leishmania major cytochrome p450-like protein 0.0028 0.0077 0.0068
Brugia malayi isocitrate dehydrogenase 0.0016 0.0026 0.0034
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0044 0.0142 0.0249
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0253 0.0303
Brugia malayi larval opioid receptor 0.0012 0.0009 0.0012
Brugia malayi Zinc finger, C2H2 type family protein 0.0308 0.1247 0.1655
Echinococcus granulosus neuropeptide s receptor 0.0012 0.0009 0.0016
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0028 0.0077 0.0301
Loa Loa (eye worm) cytochrome P450 0.0028 0.0077 0.0102
Trichomonas vaginalis aldehyde oxidase, putative 0.0707 0.2914 1
Loa Loa (eye worm) hypothetical protein 0.1814 0.7535 1
Onchocerca volvulus 0.0012 0.0009 0.0026
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0141 0.0549 0.0965
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0009 0.0009
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0046 0.0181
Echinococcus multilocularis tankyrase 0.0068 0.0245 0.0245
Mycobacterium ulcerans oxidoreductase 0.0044 0.0142 0.0558
Loa Loa (eye worm) hypothetical protein 0.0098 0.037 0.0492
Schistosoma mansoni wnt related 0.0014 0.0016 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Trichomonas vaginalis Ferredoxin 2 0.0023 0.0055 0.0188
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0137 0.0533 0.0938
Schistosoma mansoni coup transcription factor 0.0021 0.0046 0.0081
Brugia malayi ORL1-like opioid receptor 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0016
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.009 0.009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0167 0.0606
Echinococcus granulosus neuropeptide receptor A26 0.0012 0.0009 0.0016
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0046 0.0087
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0469 0.1917 0.7541
Entamoeba histolytica P-glycoprotein-2, putative 0.0016 0.0027 0.0258
Loa Loa (eye worm) hypothetical protein 0.0026 0.007 0.0093
Entamoeba histolytica ABC transporter, putative 0.0017 0.003 0.0291
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0044 0.0142 0.1637
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0042 0.0166
Echinococcus granulosus 7tm_1 domain containing protein 0.0012 0.0009 0.0016
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Schistosoma mansoni multidrug resistance protein 0.0016 0.0027 0.0047
Schistosoma mansoni hypothetical protein 0.0012 0.0009 0.0016
Giardia lamblia MRP-like ABC transporter 0.0017 0.003 0.0291
Brugia malayi tailless protein 0.001 0.0001 0.0001
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Trichomonas vaginalis Ferredoxin 1 0.0023 0.0055 0.0188
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0009 0.0012
Mycobacterium ulcerans fatty-acid-CoA ligase 0.007 0.0253 0.0996
Trypanosoma cruzi UDP-galactopyranose mutase 0.0044 0.0142 0.0188
Onchocerca volvulus 0.0012 0.0009 0.0026
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1814 0.7535 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0009 0.0012
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0707 0.2914 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0255 0.1027 0.1027
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0141 0.0549 0.0549
Onchocerca volvulus 0.0027 0.0072 0.0209
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0161 0.0283
Brugia malayi Tachykinin-like peptides receptor 99D 0.0012 0.0009 0.0012
Schistosoma mansoni multidrug resistance protein 0.0053 0.0181 0.0319
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0017 0.003 0.0006
Entamoeba histolytica P-glycoprotein-1 0.0053 0.0181 0.1767
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0046 0.0181
Schistosoma mansoni amine GPCR 0.0012 0.0009 0.0016
Echinococcus multilocularis lipoxygenase domain containing protein 0.0217 0.0866 0.0866
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0161 0.0214
Onchocerca volvulus 0.0255 0.1027 0.2994
Onchocerca volvulus 0.0027 0.0072 0.0209
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0065 0.0086
Brugia malayi Tnks protein 0.0068 0.0244 0.0324
Trichomonas vaginalis ABC transporter, putative 0.0053 0.0181 0.0623
Onchocerca volvulus Protein patched homolog 0.0012 0.0009 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0141 0.0549 0.0728
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0061
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.007 0.0253 0.0996
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0041 0.0397
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0026 0.0034
Onchocerca volvulus 0.0211 0.0841 0.2454
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0046 0.0061
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0028 0.0077 0.0218
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0001 0.0001
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0224 0.0849
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0017 0.003 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Brugia malayi ABC transporter family protein 0.0017 0.003 0.004
Brugia malayi Patched related family protein 12 0.0012 0.0009 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0142 0.1637
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0161 0.0283
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0334 0.1353 0.5322
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0044 0.0142 0.0142
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0012 0.0009 0.0016
Plasmodium vivax ABC transporter B family member 3, putative 0.0017 0.003 0.0345
Onchocerca volvulus 0.0021 0.0046 0.0134
Brugia malayi P-glycoprotein-like protein 0.0017 0.003 0.004
Plasmodium vivax ferredoxin, putative 0.0023 0.0055 0.0634
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0167 0.0606
Schistosoma mansoni histamine h1 receptor 0.0012 0.0009 0.0016
Echinococcus multilocularis neuropeptide s receptor 0.0012 0.0009 0.0009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0224 0.0881
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0012 0.0009 0.0009
Echinococcus multilocularis allatostatin A receptor 0.0012 0.0009 0.0009
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0217 0.0866 0.1523
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0149 0.0587
Plasmodium vivax ABC transporter B family member 6, putative 0.0017 0.003 0.0345
Loa Loa (eye worm) carboxylesterase 0.0137 0.0533 0.0708
Brugia malayi ABC transporter 0.0016 0.0027 0.0035
Onchocerca volvulus 0.0012 0.0009 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0028 0.0077 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0001 0.0002
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0074 0.0269 0.0473
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0009 0.0016
Entamoeba histolytica P-glycoprotein 6, putative 0.0017 0.003 0.0291
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0137 0.0533 0.2175
Echinococcus multilocularis G protein coupled receptor 139 0.0012 0.0009 0.0009
Loa Loa (eye worm) doublecortin family protein 0.0217 0.0866 0.1149
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0012 0.0009 0.0012
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0046 0.0081
Echinococcus granulosus neuropeptide FF receptor 2 0.0012 0.0009 0.0016
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0012 0.0009 0.0012
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0053 0.0181 0.0623
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0044 0.0142 0.1381
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0161 0.0283
Onchocerca volvulus 0.0012 0.0009 0.0026
Schistosoma mansoni alpha-1 adrenergic receptor 0.0012 0.0009 0.0016
Brugia malayi hypothetical protein 0.0025 0.0065 0.0086
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0006 0.0007
Loa Loa (eye worm) ABC transporter 0.0017 0.003 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0046 0.0061
Schistosoma mansoni zinc finger protein 0.001 0.0001 0.0001
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0012 0.0009 0.0009
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0135 0.0524 0.2061
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0026 0.0034
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0026 0.0034
Brugia malayi Niemann-Pick C1 protein precursor 0.0194 0.0769 0.1021
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.001 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.001 0.0001 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Onchocerca volvulus 0.0012 0.0009 0.0026
Schistosoma mansoni growth hormone secretagogue receptor 0.0012 0.0009 0.0016
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0255 0.1027 0.1027
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0053 0.0181 0.0623
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0255 0.1027 0.3523
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0046 0.0181
Loa Loa (eye worm) hypothetical protein 0.007 0.0253 0.0336
Onchocerca volvulus 0.0141 0.0549 0.16
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0142 0.0497
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0046 0.0061
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0028 0.0077 0.0301
Leishmania major ferredoxin 2fe-2s-like protein 0.0023 0.0055 0.0039
Loa Loa (eye worm) hypothetical protein 0.0017 0.003 0.004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0167 0.0606
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0026 0.025
Onchocerca volvulus Neuropeptide F receptor homolog 0.0012 0.0009 0.0026
Toxoplasma gondii histone lysine-specific demethylase 0.0044 0.0142 0.1381
Mycobacterium leprae Conserved hypothetical protein 0.0181 0.0718 0.699
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0012 0.0009 0.0012
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0053 0.0181 0.0181
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0028 0.0077 0.0218
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0053 0.0181 0.0623
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0053 0.0181 0.1767
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0046 0.0531
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0141 0.0549 0.5345
Plasmodium vivax ABC transporter G family member 2, putative 0.002 0.0042 0.0487
Echinococcus granulosus Protein Wnt-111 0.0014 0.0016 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0083 0.0307 0.0408
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0046 0.0061
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0255 0.1027 0.1806
Trichomonas vaginalis aldo-keto reductase, putative 0.0255 0.1027 0.3523
Entamoeba histolytica hypothetical protein 0.001 0.0001 0.0007
Echinococcus granulosus alpha 1A adrenergic receptor 0.0012 0.0009 0.0016
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0137 0.0533 0.0533
Echinococcus granulosus somatostatin receptor 0.0012 0.0009 0.0016
Toxoplasma gondii patched family protein 0.0012 0.0009 0.0087
Echinococcus multilocularis WNT 0.0014 0.0016 0.0016
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0026 0.0026
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0239 0.0957 0.3766
Plasmodium falciparum ABC transporter B family member 6, putative 0.0017 0.003 0.0345
Plasmodium falciparum multidrug resistance-associated protein 2 0.0017 0.003 0.0345
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0046 0.0081
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0001 0.0001
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0007 0.0007
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0017 0.003 0.0006
Brugia malayi Patched family protein 0.0012 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0028 0.0077 0.0135
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0007
Brugia malayi Carboxylesterase family protein 0.0813 0.3353 0.445
Echinococcus granulosus neuropeptide receptor 0.0012 0.0009 0.0016
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0046 0.0135
Echinococcus multilocularis insulin receptor 0.0095 0.0355 0.0355
Brugia malayi GnHR receptor homolog 0.0012 0.0009 0.0012
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0009 0.0009
Schistosoma mansoni tyrosine kinase 0.0157 0.0617 0.1085
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0255 0.1027 0.1027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0194 0.0769 0.1021
Onchocerca volvulus 0.0217 0.0866 0.2525
Schistosoma mansoni rab6-interacting 0.0217 0.0866 0.1523
Onchocerca volvulus 0.0012 0.0009 0.0026
Schistosoma mansoni multidrug resistance protein 0.0017 0.003 0.0053
Brugia malayi ABC transporter family protein 0.0017 0.003 0.004
Schistosoma mansoni opsin-like receptor 0.0012 0.0009 0.0016
Trypanosoma cruzi adrenodoxin precursor, putative 0.0023 0.0055 0.0073
Loa Loa (eye worm) CWN-2 protein 0.0014 0.0016 0.0022
Brugia malayi protein C24B5.3 0.0012 0.0009 0.0012
Mycobacterium ulcerans oxygenase 0.0023 0.0055 0.0216
Loa Loa (eye worm) hypothetical protein 0.0813 0.3353 0.445
Entamoeba histolytica alcohol dehydrogenase, putative 0.0074 0.0269 0.2619
Toxoplasma gondii aldose reductase, putative 0.0255 0.1027 1
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0074 0.0269 0.0357
Brugia malayi wnt family protein 0.0014 0.0016 0.0022
Loa Loa (eye worm) oxidoreductase 0.0255 0.1027 0.1363
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.037 0.0492
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0012

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 0.5 ug ml-1 In vitro minimum inhibitory concentration against Mycobacterium tuberculosis CIP 103471 was determined ChEMBL. 9873376
MIC (functional) = 0.5 ug ml-1 In vitro minimum inhibitory concentration against Mycobacterium tuberculosis CIP 103471 was determined ChEMBL. 9873376
MIC (functional) = 4 ug ml-1 In vitro cytotoxicity against Mycobacterium avium (CIP 103317) was determined ChEMBL. 9873376
MIC (functional) = 8 ug ml-1 In vitro cytotoxicity against Mycobacterium marinum (CIP 6423) was determined ChEMBL. 9873376
MIC (functional) > 16 ug ml-1 In vitro cytotoxicity against Mycobacterium smegmatis CIP (103599) was determined ChEMBL. 9873376
MIC (functional) > 16 ug ml-1 In vitro cytotoxicity against Mycobacterium gordonae (CIP 6427) was determined ChEMBL. 9873376
MTD50 (functional) = 8 ug ml-1 Minimal toxic dose that induced a reduction of 50% of cell growth in Vero cell line infected with Mycobacterium tuberculosis CIP 103471 ChEMBL. 9873376

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.