Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Plasmodium falciparum | adenosine deaminase | Curated by TDR Targets | References |
Species | Potential target | Raw | Global | Species |
---|
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
Affected Entity | Phenotypic quality | Occurs in | Occurs at | Evidence | Observed in | Targets |
---|---|---|---|---|---|---|
growth (GO:0040007) | lethal (sensu genetics) (PATO:0000718) | multi-cellular organism (CARO:0000012) | bloodstream stage (PLO:0040) | in vivo inhibition (TDR:00016) | Plasmodium falciparum | 1363 |
Annotator: | saralph@unimelb.edu.au | Comment: | Drug: deoxycoformycin. | References: | 10639753 15576366 |
10 literature references were collected for this gene.