Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Carboxylesterase family protein | 0.2614 | 0.5 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.2614 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2614 | 0.5 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.2614 | 0.5 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.2614 | 0.5 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.2614 | 0.5 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.2614 | 0.5 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.2614 | 0.5 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.2614 | 0.5 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.2614 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2614 | 0.5 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.2614 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Proliferative response (functional) | = 7 | Proliferation induced by the mitogen alone-PHA (control blastogenesis), in Mice cells at a dose of 5 ug/mL | ChEMBL. | 2033579 |
Proliferative response (functional) | = 11.1 | Maximal proliferation induced in the presence of the mitogen-PHA ( stimulated blastogenesis)in Mice cells at a dose of 5 ug/mL | ChEMBL. | 2033579 |
Proliferative response (functional) | = 40.5 | Proliferation induced by the mitogen alone-PWM (control blastogenesis), in Mice cells at a dose of 40 ug/mL | ChEMBL. | 2033579 |
Proliferative response (functional) | = 56.4 | Maximal proliferation induced in the presence of the mitogen-PWM ( stimulated blastogenesis)in Mice cells at a dose of 40 ug/mL | ChEMBL. | 2033579 |
Proliferative response (functional) | = 118.7 | Proliferation induced by the mitogen alone-Concanavalin A (control blastogenesis), in mice cells dosed at 5 ug/mL | ChEMBL. | 2033579 |
Proliferative response (functional) | = 123.4 | Maximal proliferation induced in the presence of the mitogen-Concanavalin A (stimulated blastogenesis)in mice cells dosed at 5 ug/mL | ChEMBL. | 2033579 |
Proliferative response (functional) | = 7 | Proliferation induced by the mitogen alone-PHA (control blastogenesis), in Mice cells at a dose of 5 ug/mL | ChEMBL. | 2033579 |
Proliferative response (functional) | = 11.1 | Maximal proliferation induced in the presence of the mitogen-PHA ( stimulated blastogenesis)in Mice cells at a dose of 5 ug/mL | ChEMBL. | 2033579 |
Proliferative response (functional) | = 40.5 | Proliferation induced by the mitogen alone-PWM (control blastogenesis), in Mice cells at a dose of 40 ug/mL | ChEMBL. | 2033579 |
Proliferative response (functional) | = 56.4 | Maximal proliferation induced in the presence of the mitogen-PWM ( stimulated blastogenesis)in Mice cells at a dose of 40 ug/mL | ChEMBL. | 2033579 |
Proliferative response (functional) | = 118.7 | Proliferation induced by the mitogen alone-Concanavalin A (control blastogenesis), in mice cells dosed at 5 ug/mL | ChEMBL. | 2033579 |
Proliferative response (functional) | = 123.4 | Maximal proliferation induced in the presence of the mitogen-Concanavalin A (stimulated blastogenesis)in mice cells dosed at 5 ug/mL | ChEMBL. | 2033579 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.