Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | hypothetical protein, conserved | 0.0049 | 0.3368 | 0.3145 |
Trypanosoma brucei | NADH-dependent fumarate reductase, putative | 0.0015 | 0.048 | 0.016 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0128 | 1 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.1388 | 0.1098 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0037 | 0.2336 | 0.2079 |
Trypanosoma cruzi | cytochrome-b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Leishmania major | oxidoreductase-like protein | 0.0015 | 0.048 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1388 | 0.138 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.4449 | 0.4262 |
Trypanosoma brucei | antigen, putative | 0.0019 | 0.0834 | 0.0526 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0019 | 0.0834 | 0.0526 |
Trypanosoma brucei | calpain-like protein, putative | 0.0019 | 0.0834 | 0.0526 |
Schistosoma mansoni | jumonji domain containing protein | 0.0015 | 0.0535 | 0.037 |
Onchocerca volvulus | 0.0026 | 0.1475 | 0.4646 | |
Echinococcus granulosus | calpain 7 C02 family | 0.0019 | 0.0834 | 0.0825 |
Leishmania major | cysteine peptidase A (CPA) | 0.0016 | 0.0621 | 0.0306 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0059 | 0.4182 | 0.4081 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.4449 | 0.4262 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0059 | 0.4182 | 0.4176 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0621 | 0.0612 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0621 | 0.0612 |
Toxoplasma gondii | thioredoxin reductase | 0.0037 | 0.2336 | 0.4717 |
Plasmodium vivax | glutathione reductase, putative | 0.0037 | 0.2336 | 0.2079 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0037 | 0.2378 | 0.237 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0093 | 0.7062 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0535 | 0.0526 |
Trypanosoma cruzi | p450 reductase, putative | 0.0015 | 0.048 | 0.016 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0013 | 0.0326 | 0.5 |
Brugia malayi | calpain 7 | 0.0019 | 0.0834 | 0.0834 |
Plasmodium falciparum | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0049 | 0.3368 | 0.3145 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0037 | 0.2336 | 0.2985 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0084 | 0.6279 | 0.8837 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0084 | 0.6279 | 0.8837 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0015 | 0.048 | 0.016 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0016 | 0.0621 | 0.0306 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.4182 | 0.4176 |
Onchocerca volvulus | 0.0016 | 0.0621 | 0.1605 | |
Brugia malayi | intermediate filament protein | 0.0026 | 0.1475 | 0.1475 |
Echinococcus multilocularis | lamin | 0.0026 | 0.1475 | 0.1467 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0535 | 0.0526 |
Trypanosoma cruzi | NADPH--cytochrome P450 reductase, putative | 0.0049 | 0.3368 | 0.3145 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0049 | 0.3368 | 0.3145 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0049 | 0.3368 | 1 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0621 | 0.0306 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0214 | 0.0205 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0011 | 0.0171 | 0.0171 |
Toxoplasma gondii | NADH-cytochrome b5 reductase 1, putative | 0.0015 | 0.048 | 0.0363 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0535 | 0.0526 |
Schistosoma mansoni | calpain (C02 family) | 0.0019 | 0.0834 | 0.0675 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0128 | 1 | 1 |
Loa Loa (eye worm) | cytochrome b5 reductase 4 | 0.0015 | 0.048 | 0.0471 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0834 | 0.0526 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0063 | 0.4589 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.2215 | 0.6394 |
Leishmania major | calpain, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0834 | 0.0526 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.4449 | 0.4262 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0128 | 1 | 1 |
Giardia lamblia | Flavohemoprotein lateral transfer candidate | 0.0015 | 0.048 | 0.0183 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.0171 | 0.0171 |
Giardia lamblia | Nitric oxide synthase, inducible | 0.0113 | 0.8779 | 1 |
Onchocerca volvulus | 0.0016 | 0.0621 | 0.1605 | |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.1475 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 1 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0093 | 0.7062 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.4449 | 0.4262 |
Trypanosoma brucei | calpain-like protein, putative | 0.0019 | 0.0834 | 0.0526 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.1475 | 0.1326 |
Leishmania major | cytochrome-b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Echinococcus granulosus | phd:f box containing protein | 0.0015 | 0.0535 | 0.0526 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.2977 | 0.297 |
Echinococcus multilocularis | calpain | 0.0019 | 0.0834 | 0.0825 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0128 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.0621 | 0.1409 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0015 | 0.0535 | 0.0217 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Echinococcus multilocularis | phd:f box containing protein | 0.0015 | 0.0535 | 0.0526 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0128 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.2215 | 0.6394 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0621 | 0.0621 |
Trypanosoma cruzi | kinesin, putative | 0.0019 | 0.0834 | 0.0526 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0049 | 0.3368 | 0.3145 |
Loa Loa (eye worm) | diaphorase | 0.0015 | 0.048 | 0.0471 |
Onchocerca volvulus | Cathepsin F homolog | 0.0016 | 0.0621 | 0.1605 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0016 | 0.0621 | 0.0612 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.2215 | 0.6394 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0834 | 0.0526 |
Entamoeba histolytica | cysteine protease, putative | 0.0016 | 0.0621 | 0.1409 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0535 | 0.0535 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0621 | 0.0458 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0009 | 0.0042 | 0.0042 |
Leishmania major | trypanothione reductase | 0.0037 | 0.2336 | 0.2079 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0093 | 0.7062 | 1 |
Plasmodium falciparum | NADPH--cytochrome P450 reductase, putative | 0.0049 | 0.3368 | 0.3145 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0037 | 0.2336 | 0.2329 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0834 | 0.0526 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0128 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0016 | 0.0621 | 0.0612 |
Plasmodium vivax | JmjC domain containing protein | 0.0015 | 0.0535 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0328 | 0.0319 |
Brugia malayi | hypothetical protein | 0.0035 | 0.2215 | 0.2215 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.4449 | 0.4262 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0015 | 0.0535 | 0.0217 |
Leishmania major | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.4449 | 0.4262 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0621 | 0.0612 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0049 | 0.3368 | 0.3252 |
Mycobacterium ulcerans | oxidoreductase | 0.0015 | 0.048 | 0.016 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.1388 | 0.1098 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0044 | 0.2977 | 0.297 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.1388 | 0.1098 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0084 | 0.6279 | 0.8837 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0621 | 0.0621 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0015 | 0.048 | 0.023 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0015 | 0.0535 | 0.0526 |
Loa Loa (eye worm) | calpain | 0.0019 | 0.0834 | 0.0825 |
Trichomonas vaginalis | NADPH fad oxidoreductase, putative | 0.0113 | 0.8779 | 0.8758 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0834 | 0.0526 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0013 | 0.0326 | 0.0316 |
Trypanosoma cruzi | calpain cysteine peptidase, putative | 0.0019 | 0.0834 | 0.0526 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.4449 | 0.4262 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0015 | 0.0535 | 0.037 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0128 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.4449 | 0.4262 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0019 | 0.0834 | 0.0675 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0535 | 0.0217 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0059 | 0.4182 | 0.4081 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1475 | 0.1467 |
Echinococcus granulosus | NADH cytochrome b5 reductase 3 | 0.0015 | 0.048 | 0.0471 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Plasmodium vivax | calpain, putative | 0.0019 | 0.0834 | 0.0526 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0063 | 0.4552 | 0.4457 |
Schistosoma mansoni | Mername-AA248 (C02 family) | 0.0019 | 0.0834 | 0.0675 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0037 | 0.2336 | 0.2079 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0066 | 0.4822 | 0.4732 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0015 | 0.048 | 0.016 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.0621 | 0.1605 |
Echinococcus granulosus | lamin | 0.0026 | 0.1475 | 0.1467 |
Brugia malayi | Cytochrome b5-like Heme/Steroid binding domain containing protein | 0.0015 | 0.048 | 0.048 |
Leishmania major | reductase, putative | 0.0015 | 0.048 | 0.016 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0634 | 0.0634 |
Leishmania major | cytochrome P450 reductase, putative | 0.0113 | 0.8779 | 0.8738 |
Echinococcus multilocularis | calpain 5 | 0.0019 | 0.0834 | 0.0825 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.1388 | 0.1098 |
Schistosoma mansoni | phd/f-box containing protein | 0.0015 | 0.0535 | 0.037 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0621 | 0.0621 |
Plasmodium vivax | hypothetical protein, conserved | 0.0049 | 0.3368 | 0.3145 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0013 | 0.0326 | 0.0316 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Onchocerca volvulus | 0.0029 | 0.1685 | 0.5395 | |
Leishmania major | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.2215 | 0.2207 |
Brugia malayi | FAD binding domain containing protein | 0.0128 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0834 | 0.0526 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0049 | 0.3368 | 0.3252 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0019 | 0.0834 | 0.0675 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0015 | 0.048 | 0.016 |
Loa Loa (eye worm) | ctsf protein | 0.0016 | 0.0621 | 0.0612 |
Schistosoma mansoni | lamin | 0.0026 | 0.1475 | 0.1326 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.1685 | 0.1677 |
Echinococcus multilocularis | calpain A | 0.0066 | 0.4822 | 0.4817 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.4552 | 0.4546 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0621 | 0.0458 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0015 | 0.0535 | 0.0526 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0009 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0128 | 1 | 1 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0128 | 1 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0057 | 0.4044 | 0.4044 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0049 | 0.3368 | 1 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0015 | 0.048 | 0.016 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0013 | 0.0326 | 0.5 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.1475 | 0.1475 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Entamoeba histolytica | calpain large subunit domain III containing protein | 0.0019 | 0.0834 | 0.2074 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0214 | 0.0044 |
Leishmania major | nitrate reductase, putative | 0.0015 | 0.048 | 0.016 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.1823 | 0.1815 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Echinococcus granulosus | methionine synthase reductase | 0.0079 | 0.5891 | 0.5888 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0013 | 0.0326 | 0.0157 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0017 | 0.0673 | 0.0664 |
Mycobacterium tuberculosis | Probable reductase | 0.0084 | 0.6279 | 0.8837 |
Trypanosoma brucei | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0049 | 0.3368 | 0.3145 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0621 | 0.0621 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Onchocerca volvulus | 0.0026 | 0.1475 | 0.4646 | |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.0621 | 0.0306 |
Plasmodium vivax | ferredoxin--NADP reductase, putative | 0.0015 | 0.048 | 0.016 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.1388 | 0.1098 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.4449 | 0.4262 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0015 | 0.0535 | 0.0526 |
Brugia malayi | hypothetical protein | 0.0025 | 0.1388 | 0.1388 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.4449 | 0.4262 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.1823 | 0.1681 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0015 | 0.0535 | 0.0491 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.0621 | 0.1605 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0093 | 0.7062 | 1 |
Brugia malayi | glutathione reductase | 0.0037 | 0.2336 | 0.2336 |
Schistosoma mansoni | protein phosphatase 2C | 0.0015 | 0.0535 | 0.037 |
Trypanosoma brucei | NADH-dependent fumarate reductase, putative | 0.0015 | 0.048 | 0.016 |
Trypanosoma cruzi | oxidoreductase-protein, putative | 0.0015 | 0.048 | 0.016 |
Echinococcus multilocularis | cytochrome b5 reductase 4 | 0.0015 | 0.048 | 0.0471 |
Schistosoma mansoni | NADPH flavin oxidoreductase | 0.0064 | 0.467 | 0.4578 |
Trypanosoma cruzi | nitrate reductase, putative | 0.0015 | 0.048 | 0.016 |
Loa Loa (eye worm) | fibroinase | 0.0016 | 0.0621 | 0.0612 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0013 | 0.0326 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0288 | 0.0279 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0056 | 0.3999 | 0.3797 |
Plasmodium falciparum | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Chlamydia trachomatis | Na(+)-translocating NADH-quinone reductase subunit F | 0.0015 | 0.048 | 0.0278 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0128 | 1 | 1 |
Trypanosoma brucei | calpain-like protein, putative | 0.0019 | 0.0834 | 0.0526 |
Schistosoma mansoni | jumonji domain containing protein | 0.0057 | 0.4044 | 0.394 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.4449 | 0.4262 |
Trypanosoma brucei | NADH-cytochrome b5 reductase-like protein | 0.0015 | 0.048 | 0.016 |
Chlamydia trachomatis | sulfite reductase | 0.0079 | 0.5891 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Loa Loa (eye worm) | flavodoxin family protein | 0.0049 | 0.3368 | 0.3361 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0063 | 0.4552 | 0.4546 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0288 | 0.0279 |
Mycobacterium tuberculosis | Hypothetical oxidoreductase | 0.0015 | 0.048 | 0.023 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0049 | 0.3368 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.4449 | 0.4262 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0621 | 0.0306 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.1475 | 0.1467 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0079 | 0.5891 | 0.5888 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0535 | 0.0535 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0621 | 0.0612 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.1388 | 0.2492 |
Trypanosoma cruzi | p450 reductase, putative | 0.0128 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0621 | 0.0621 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Schistosoma mansoni | diflavin oxidoreductase | 0.0063 | 0.4589 | 0.4495 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.1685 | 0.1685 |
Loa Loa (eye worm) | glutathione reductase | 0.0037 | 0.2336 | 0.2329 |
Trypanosoma cruzi | kinesin, putative | 0.0019 | 0.0834 | 0.0526 |
Brugia malayi | FAD binding domain containing protein | 0.0079 | 0.5891 | 0.5891 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0128 | 1 | 1 |
Echinococcus multilocularis | calpain 7 (C02 family) | 0.0019 | 0.0834 | 0.0825 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.1475 | 0.1467 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0128 | 1 | 1 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0128 | 1 | 1 |
Trypanosoma brucei | calpain-like protein, putative | 0.0019 | 0.0834 | 0.0526 |
Schistosoma mansoni | cytochrome B5 | 0.0015 | 0.048 | 0.0315 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0015 | 0.048 | 0.016 |
Mycobacterium ulcerans | electron transfer protein FdxB | 0.0015 | 0.048 | 0.016 |
Echinococcus granulosus | calpain A | 0.0019 | 0.0834 | 0.0825 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Leishmania major | kinesin, putative | 0.0019 | 0.0834 | 0.0526 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0084 | 0.6279 | 0.8837 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Loa Loa (eye worm) | cysteine protease | 0.0016 | 0.0621 | 0.0612 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.1388 | 0.1098 |
Mycobacterium ulcerans | oxygenase | 0.0015 | 0.048 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1434 | 0.1426 |
Trypanosoma cruzi | cytochrome-b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Brugia malayi | calpain family protein 1 | 0.0063 | 0.4552 | 0.4552 |
Brugia malayi | calpain 5 | 0.0019 | 0.0834 | 0.0834 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0535 | 0.0535 |
Trypanosoma brucei | NADH-dependent fumarate reductase | 0.0015 | 0.048 | 0.016 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0057 | 0.4044 | 0.4038 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0171 | 0.0162 |
Echinococcus granulosus | calpain 5 | 0.0019 | 0.0834 | 0.0825 |
Plasmodium vivax | flavodoxin domain containing protein | 0.0113 | 0.8779 | 0.8738 |
Trypanosoma brucei | nitrate reductase, putative | 0.0015 | 0.048 | 0.016 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0535 | 0.0535 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0016 | 0.0621 | 0.0306 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0049 | 0.3338 | 0.3114 |
Mycobacterium ulcerans | monooxygenase | 0.0015 | 0.048 | 0.016 |
Trypanosoma brucei | trypanothione reductase | 0.0037 | 0.2336 | 0.2079 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0084 | 0.6279 | 0.8837 |
Mycobacterium tuberculosis | Possible oxygenase | 0.0015 | 0.048 | 0.023 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0016 | 0.0621 | 0.0306 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0037 | 0.2378 | 0.237 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0066 | 0.4822 | 0.4732 |
Onchocerca volvulus | 0.0044 | 0.2977 | 1 | |
Schistosoma mansoni | NADH-cytochrome B5 reductase | 0.0015 | 0.048 | 0.0315 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0328 | 0.0319 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0621 | 0.0612 |
Echinococcus multilocularis | NADH cytochrome b5 reductase 3 | 0.0015 | 0.048 | 0.0471 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0019 | 0.0834 | 0.0526 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0079 | 0.5891 | 0.582 |
Schistosoma mansoni | lamin | 0.0026 | 0.1475 | 0.1326 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0015 | 0.0535 | 0.0526 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Onchocerca volvulus | 0.0016 | 0.0621 | 0.1605 | |
Brugia malayi | diaphorase | 0.0015 | 0.048 | 0.048 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.2215 | 0.2079 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.2215 | 0.2079 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.4449 | 0.4262 |
Echinococcus multilocularis | hypothetical protein | 0.0019 | 0.0834 | 0.0825 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0016 | 0.0621 | 0.0306 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0015 | 0.0535 | 0.0491 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0535 | 0.0526 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.1685 | 0.154 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0044 | 0.2977 | 0.297 |
Entamoeba histolytica | protein kinase, putative | 0.0019 | 0.0834 | 0.2074 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0015 | 0.0535 | 0.0217 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0015 | 0.048 | 0.016 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0621 | 0.0306 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0057 | 0.4044 | 0.4038 |
Mycobacterium tuberculosis | Probable monooxygenase | 0.0015 | 0.048 | 0.023 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.4449 | 0.4262 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0621 | 0.0306 |
Onchocerca volvulus | 0.0016 | 0.0621 | 0.1605 | |
Entamoeba histolytica | type A flavoprotein, putative | 0.0049 | 0.3368 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0535 | 0.0526 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.4449 | 0.4262 |
Echinococcus multilocularis | methionine synthase reductase | 0.0079 | 0.5891 | 0.5888 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0015 | 0.0535 | 0.0526 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.0621 | 0.0306 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0013 | 0.0326 | 0.0157 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0049 | 0.3368 | 0.3252 |
Plasmodium falciparum | glutathione reductase | 0.0037 | 0.2336 | 0.2079 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0016 | 0.0621 | 0.0612 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0128 | 1 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.2215 | 0.2207 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0013 | 0.0326 | 0.0326 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0128 | 1 | 1 |
Trypanosoma brucei | kinesin, putative | 0.0019 | 0.0834 | 0.0526 |
Echinococcus granulosus | cytochrome b5 reductase 4 | 0.0015 | 0.048 | 0.0471 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0015 | 0.0535 | 0.0526 |
Onchocerca volvulus | 0.0016 | 0.0621 | 0.1605 | |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.1475 | 0.1467 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0016 | 0.0621 | 0.0612 |
Mycobacterium ulcerans | flavodoxin oxidoreductase | 0.0015 | 0.048 | 0.016 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0834 | 0.0526 |
Plasmodium vivax | oxidoreductase NAD-binding domain containing protein | 0.0015 | 0.048 | 0.016 |
Trypanosoma cruzi | reductase, putative | 0.0015 | 0.048 | 0.016 |
Giardia lamblia | Hypothetical protein | 0.0113 | 0.8779 | 1 |
Echinococcus granulosus | cytochrome b5 reductase 4 | 0.0015 | 0.048 | 0.0471 |
Onchocerca volvulus | 0.0016 | 0.0621 | 0.1605 | |
Leishmania major | NADH-dependent fumarate reductase-like protein | 0.0015 | 0.048 | 0.016 |
Leishmania major | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0128 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.0621 | 0.1409 |
Brugia malayi | jmjC domain containing protein | 0.0059 | 0.4182 | 0.4182 |
Leishmania major | cytochrome-b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Mycobacterium ulcerans | flavodoxin reductase Hmp | 0.0015 | 0.048 | 0.016 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.1823 | 0.1815 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0019 | 0.0834 | 0.0526 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0019 | 0.0834 | 0.0526 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.4449 | 0.4262 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0066 | 0.4822 | 0.4817 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0446 | 0.0437 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0017 | 0.0673 | 0.0664 |
Leishmania major | p450 reductase, putative | 0.0128 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.4552 | 0.4546 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.3855 | 0.8278 |
Echinococcus granulosus | calpain | 0.0019 | 0.0834 | 0.0825 |
Leishmania major | NADH-dependent fumarate reductase, putative | 0.0015 | 0.048 | 0.016 |
Treponema pallidum | ferredoxin-NADP(+) reductase subunit alpha | 0.0015 | 0.048 | 0.0508 |
Trypanosoma brucei | oxidoreductase-protein, putative | 0.0015 | 0.048 | 0.016 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0214 | 0.0205 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0171 | 0.0162 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0171 | 0.0162 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.1388 | 0.1098 |
Brugia malayi | calpain family protein 1 | 0.0063 | 0.4552 | 0.4552 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0063 | 0.4589 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.4404 | 0.4307 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0621 | 0.0621 |
Brugia malayi | cathepsin L-like precursor | 0.0011 | 0.0171 | 0.0171 |
Plasmodium falciparum | thioredoxin reductase | 0.0037 | 0.2336 | 0.2079 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.0171 | 0.0171 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.2977 | 0.297 |
Trypanosoma brucei | NADH-dependent fumarate reductase | 0.0015 | 0.048 | 0.016 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0057 | 0.4044 | 0.4038 |
Toxoplasma gondii | cathepsin CPL | 0.0016 | 0.0621 | 0.0694 |
Echinococcus granulosus | cathepsin l1 | 0.0011 | 0.0171 | 0.0162 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0049 | 0.3368 | 0.3252 |
Toxoplasma gondii | ferredoxin NADP+ oxidoreductase FNR | 0.0015 | 0.048 | 0.0363 |
Loa Loa (eye worm) | calpain 5 | 0.0019 | 0.0834 | 0.0825 |
Brugia malayi | Thioredoxin reductase | 0.0037 | 0.2336 | 0.2336 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0019 | 0.0834 | 0.0526 |
Treponema pallidum | flavodoxin | 0.0049 | 0.3368 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0535 | 0.0526 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.2215 | 0.6394 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0621 | 0.0306 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0328 | 0.0319 |
Onchocerca volvulus | 0.0015 | 0.048 | 0.1102 | |
Schistosoma mansoni | calpain C (C02 family) | 0.0019 | 0.0834 | 0.0675 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0019 | 0.0834 | 0.0526 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0621 | 0.0621 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.1823 | 0.1681 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0015 | 0.0535 | 0.0217 |
Echinococcus multilocularis | musashi | 0.0026 | 0.1475 | 0.1467 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.1475 | 0.1467 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0128 | 1 | 1 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0015 | 0.048 | 0.016 |
Brugia malayi | flavodoxin family protein | 0.0049 | 0.3368 | 0.3368 |
Mycobacterium tuberculosis | Possible electron transfer protein FdxB | 0.0015 | 0.048 | 0.023 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0019 | 0.0834 | 0.0526 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0621 | 0.0612 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0621 | 0.0612 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0446 | 0.0446 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0066 | 0.4822 | 0.4817 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0128 | 1 | 1 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0015 | 0.048 | 0.016 |
Plasmodium falciparum | ferredoxin--NADP reductase | 0.0015 | 0.048 | 0.016 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.4449 | 0.4262 |
Echinococcus granulosus | calpain A | 0.0066 | 0.4822 | 0.4817 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0621 | 0.0458 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.4449 | 0.4262 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0049 | 0.3368 | 1 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0015 | 0.0535 | 0.037 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0016 | 0.0621 | 0.0612 |
Onchocerca volvulus | 0.0016 | 0.0621 | 0.1605 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.