Detailed information for compound 536970

Basic information

Technical information
  • TDR Targets ID: 536970
  • Name: pyrrolidine hydrochloride
  • MW: 107.582 | Formula: C4H10ClN
  • H donors: 1 H acceptors: 0 LogP: 1.09 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: C1CCCN1.Cl
  • InChi: 1S/C4H9N.ClH/c1-2-4-5-3-1;/h5H,1-4H2;1H
  • InChiKey: FCLZCOCSZQNREK-UHFFFAOYSA-N  

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Synonyms

  • hydron; pyrrolidine; chloride
  • pyrrolidine
  • 123-75-1
  • NSC 203096

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major gamma-tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major zeta tubulin, putative Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major delta tubulin, putative Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major epsilon tubulin, putative Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major alpha tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References
Leishmania major beta tubulin Curated by TDR Targets References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus tubulin subunit TubB Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Entamoeba histolytica tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma cruzi zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Echinococcus granulosus tubulin beta 1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Candida albicans gamma tubulin-like protein Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma brucei zeta tubulin Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania major zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Giardia lamblia Epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Trichomonas vaginalis tubulin alpha chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium falciparum tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Loa Loa (eye worm) BEN-1 protein Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) alpha-tubulin isotype 2 Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-1 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Trypanosoma congolense alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Brugia malayi beta-tubulin, identical Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Trypanosoma cruzi tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin beta 4A class IVa Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania donovani alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium falciparum alpha tubulin 1 Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium falciparum tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin, putative Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin beta-2A chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania infantum delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Trypanosoma brucei tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K07374 tubulin alpha, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium berghei alpha tubulin 1 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Gamma tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) BEN-1 protein Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit epsilon Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin epsilon chain Get druggable targets OG5_130726 All targets in OG5_130726
Plasmodium berghei alpha tubulin 2 Get druggable targets OG5_126605 All targets in OG5_126605
Entamoeba histolytica tubulin family protein Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Candida albicans gamma tubulin-like protein Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus multilocularis tubulin beta 1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi Tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Theileria parva tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Plasmodium vivax tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin, beta 4A class IVa Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense zeta tubulin Get druggable targets OG5_145938 All targets in OG5_145938
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi alpha tubulin, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania donovani zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Trypanosoma cruzi tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Theileria parva tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Echinococcus granulosus peroxisome assembly protein 26 Get druggable targets OG5_126605 All targets in OG5_126605
Cryptosporidium parvum tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii alpha-tubulin I, putative Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Babesia bovis tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Neospora caninum Beta-tubulin, related Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma cruzi beta tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus granulosus tubulin epsilon chain Get druggable targets OG5_130726 All targets in OG5_130726
Candida albicans cytoskeletal structural protein Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K07374 tubulin alpha, putative Get druggable targets OG5_126605 All targets in OG5_126605
Babesia bovis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K07375 tubulin beta, putative Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania donovani tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Theileria parva tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium knowlesi tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Theileria parva Tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis peroxisome assembly protein 26 Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii beta-tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium parvum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi Tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Plasmodium yoelii tubulin beta chain Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma japonicum Tubulin alpha-1C chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii alpha tubulin TUBA1 Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin beta-4 chain Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium berghei tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Plasmodium berghei tubulin epsilon chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii Tubulin/FtsZ family, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma cruzi zeta tubulin, putative Get druggable targets OG5_145938 All targets in OG5_145938
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma congolense epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium knowlesi tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma brucei gambiense epsilon tubulin Get druggable targets OG5_130726 All targets in OG5_130726
Babesia bovis tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma japonicum ko:K07375 tubulin beta, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Cryptosporidium hominis beta-catenin-like repeat protein Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium vivax tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi Tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma congolense tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense gamma tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K10391 tubulin epsilon, putative Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Entamoeba histolytica tubulin family protein Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-7 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium knowlesi alpha tubulin, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium berghei tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Entamoeba histolytica tubulin alpha-1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum tubulin delta chain, putative Get druggable targets OG5_143817 All targets in OG5_143817
Echinococcus granulosus tubulin gamma 1 chain Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania donovani tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-1 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi tubulin alpha chain - mouse Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium hominis alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Cryptosporidium parvum gamma tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania braziliensis epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Leishmania mexicana epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania donovani epsilon tubulin, putative Get druggable targets OG5_130726 All targets in OG5_130726
Schistosoma mansoni tubulin subunit gamma Get druggable targets OG5_127652 All targets in OG5_127652
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_130726 All targets in OG5_130726
Entamoeba histolytica tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein Get druggable targets OG5_143817 All targets in OG5_143817
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium hominis gamma-tubulin Get druggable targets OG5_127652 All targets in OG5_127652
Loa Loa (eye worm) tubulin beta-1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin alpha-3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense zeta tubulin Get druggable targets OG5_145938 All targets in OG5_145938
Toxoplasma gondii beta-1 tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major delta tubulin, putative Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum ko:K10389 tubulin gamma, putative Get druggable targets OG5_127652 All targets in OG5_127652
Toxoplasma gondii beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin beta-4 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium falciparum alpha tubulin 2 Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi Tubulin beta-1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin gamma 1 chain Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium knowlesi alpha-tubulin II, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi tubulin delta chain Get druggable targets OG5_143817 All targets in OG5_143817
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium falciparum tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium yoelii tubulin gamma chain Get druggable targets OG5_127652 All targets in OG5_127652
Echinococcus multilocularis tubulin subunit TubB Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium vivax tubulin gamma chain, putative Get druggable targets OG5_127652 All targets in OG5_127652
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin alpha-2/alpha-4 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Babesia bovis tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi Tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin epsilon chain, putative gamma-tubulin 447 aa 479 aa 28.2 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain beta tubulin 443 aa 438 aa 33.6 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Trypanosoma brucei epsilon tubulin epsilon tubulin, putative 470 aa 488 aa 68.0 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %
Plasmodium falciparum tubulin gamma chain alpha tubulin 451 aa 457 aa 30.9 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) tubulin alpha-2 chain 0.0471 0.0901 0.63
Loa Loa (eye worm) beta-lactamase 0.0035 0.0018 0.0096
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.0406 0.775
Echinococcus multilocularis tubulin alpha 1C chain 0.0471 0.0901 0.0897
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0099 0.0818
Trichomonas vaginalis tubulin, putative 0.019 0.0332 0.2734
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0088 0.0125 0.0441
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0088 0.0125 0.0998
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0018 0.0254
Onchocerca volvulus Bile acid receptor homolog 0.0091 0.013 0.0964
Toxoplasma gondii aldehyde dehydrogenase 0.0126 0.0202 0.1633
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0145 0.024 0.0236
Onchocerca volvulus 0.0097 0.0143 0.1079
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0043 0.0032 0.0201
Echinococcus granulosus dnaJ subfamily B 0.1231 0.2445 0.8917
Onchocerca volvulus 0.0609 0.1182 1
Echinococcus multilocularis geminin 0.1377 0.2741 0.2738
Loa Loa (eye worm) tubulin alpha chain 0.0471 0.0901 0.63
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0031 0.0194
Toxoplasma gondii isocitrate dehydrogenase 0.005 0.0046 0.0348
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0072 0.0475
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0091 0.013 0.0458
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0031 0.0099
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0096
Loa Loa (eye worm) tubulin gamma chain 0.0384 0.0725 0.5063
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0029 0.0004 0.0004
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0471 0.0901 0.7427
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0062 0.0479
Echinococcus multilocularis muscleblind protein 0.0468 0.0897 0.0893
Entamoeba histolytica tubulin family protein 0.0625 0.1214 1
Giardia lamblia Delta tubulin 0.0161 0.0273 0.2218
Echinococcus granulosus importin subunit beta 1 0.0058 0.0062 0.0211
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0031 0.0027
Echinococcus multilocularis nuclear receptor nhr 48 0.0043 0.0032 0.0028
Echinococcus granulosus expressed protein 0.0035 0.0016 0.0044
Loa Loa (eye worm) DR-78 0.0043 0.0032 0.0201
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0091 0.013 0.0125
Schistosoma mansoni ran 0.0042 0.0031 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0088 0.0728
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0465 0.3833
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0072 0.0245
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0119 0.0417
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0048 0.0043 0.0038
Schistosoma mansoni nuclear receptor nhr-48 0.0043 0.0032 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0091 0.013 0.0884
Loa Loa (eye worm) alpha-tubulin 0.0471 0.0901 0.63
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0284 0.0522 1
Echinococcus multilocularis beta tubulin 0.0625 0.1214 0.121
Leishmania major trypanothione reductase 0.0084 0.0115 0.0918
Trichomonas vaginalis tubulin epsilon chain, putative 0.0625 0.1214 1
Loa Loa (eye worm) tubulin alpha-3 chain 0.0281 0.0515 0.3588
Brugia malayi ecdysone receptor 0.0043 0.0032 0.0201
Trichomonas vaginalis tubulin alpha chain, putative 0.0625 0.1214 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0042 0.035
Echinococcus granulosus snurportin 1 0.0614 0.1192 0.4339
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0062 0.0479
Loa Loa (eye worm) hypothetical protein 0.0058 0.0062 0.041
Loa Loa (eye worm) hypothetical protein 0.0091 0.013 0.0884
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0029 0.0005 0.0001
Echinococcus multilocularis tumor protein p63 0.0665 0.1296 0.1292
Schistosoma mansoni alpha tubulin 0.0471 0.0901 0.3277
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0072 0.0091 0.168
Trichomonas vaginalis tubulin alpha chain, putative 0.0351 0.0659 0.5429
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0091 0.013 0.0884
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0625 0.1214 0.121
Mycobacterium ulcerans cell division protein FtsZ 0.0161 0.0273 0.518
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0043 0.0032 0.0102
Echinococcus granulosus thioredoxin glutathione reductase 0.0084 0.0116 0.0409
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0091 0.013 0.0884
Echinococcus granulosus Nuclear hormone receptor HR96 0.0043 0.0032 0.0102
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0091 0.0614
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Loa Loa (eye worm) phosphatidylinositol 3 0.003 0.0006 0.0013
Echinococcus granulosus tubulin gamma 1 chain 0.0384 0.0725 0.2634
Echinococcus granulosus tubulin alpha 0.0351 0.0659 0.2392
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0072 0.0091 0.168
Schistosoma mansoni importin beta-1 0.0058 0.0062 0.0211
Echinococcus granulosus tubulin alpha 3 chain 0.0471 0.0901 0.3277
Echinococcus granulosus Tubulin alpha 1 chain 0.0471 0.0901 0.3277
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0031 0.0224
Loa Loa (eye worm) hypothetical protein 0.0048 0.0043 0.0274
Loa Loa (eye worm) hypothetical protein 0.0199 0.0349 0.242
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0027 0.0023
Echinococcus multilocularis tubulin subunit TubB 0.0471 0.0901 0.0897
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0053 0.0435
Brugia malayi hypothetical protein 0.0129 0.0207 0.1425
Echinococcus granulosus beta tubulin 0.0625 0.1214 0.4418
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0043 0.0032 0.0028
Brugia malayi RNA binding protein 0.0062 0.0072 0.0475
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0043 0.0032 0.0201
Schistosoma mansoni tubulin subunit beta 0.0161 0.0273 0.098
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0006 0.0011
Echinococcus multilocularis GPCR, family 2 0.0176 0.0302 0.0298
Trichomonas vaginalis rotamase, putative 0.0034 0.0015 0.0121
Echinococcus multilocularis FTZ F1 alpha 0.0091 0.013 0.0125
Loa Loa (eye worm) tubulin beta-2A chain 0.0625 0.1214 0.8492
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0079 0.0652
Schistosoma mansoni tubulin subunit alpha 0.0471 0.0901 0.3277
Trypanosoma brucei beta tubulin 0.0625 0.1214 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0018 0.0144
Trichomonas vaginalis tubulin, putative 0.019 0.0332 0.2734
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0284 0.0522 1
Schistosoma mansoni tubulin subunit alpha 0.0471 0.0901 0.3277
Echinococcus multilocularis tubulin delta chain 0.0161 0.0273 0.0268
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0086 0.0299
Loa Loa (eye worm) hypothetical protein 0.0048 0.0043 0.0274
Leishmania major beta tubulin 0.0625 0.1214 1
Brugia malayi hypothetical protein 0.0145 0.024 0.1658
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0286 0.236
Schistosoma mansoni lamin 0.0054 0.0054 0.0183
Loa Loa (eye worm) isocitrate dehydrogenase 0.005 0.0046 0.0299
Schistosoma mansoni hypothetical protein 0.0176 0.0302 0.1088
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.1214 0.121
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0005 0.0003
Onchocerca volvulus Protein ultraspiracle homolog 0.0091 0.013 0.0964
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0105 0.0832
Brugia malayi CXXC zinc finger family protein 0.0118 0.0186 0.1279
Echinococcus granulosus mixed lineage leukemia protein mll 0.0029 0.0005 0.0003
Echinococcus multilocularis snurportin 1 0.0614 0.1192 0.1188
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0005 0.0001
Plasmodium vivax tubulin beta chain, putative 0.0625 0.1214 1
Loa Loa (eye worm) tubulin beta-4 chain 0.0625 0.1214 0.8492
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0176 0.0302 0.2094
Trichomonas vaginalis esterase, putative 0.0035 0.0018 0.0144
Leishmania major beta tubulin 0.0625 0.1214 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1126 0.9278
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0015 0.0085
Trypanosoma brucei isocitrate dehydrogenase, putative 0.005 0.0046 0.0348
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0091 0.0614
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0099 0.0818
Echinococcus multilocularis lamin dm0 0.0054 0.0054 0.005
Trypanosoma cruzi tubulin gamma chain 0.0384 0.0725 0.5961
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.005 0.0378
Trypanosoma brucei beta tubulin 0.0625 0.1214 1
Trypanosoma brucei zeta tubulin 0.0498 0.0957 0.7874
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0088 0.0125 0.0998
Trypanosoma cruzi trypanothione reductase, putative 0.0084 0.0115 0.0918
Mycobacterium tuberculosis Probable oxidoreductase 0.0212 0.0376 0.7185
Treponema pallidum cell division protein FtsZ 0.0161 0.0273 0.2391
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0049 0.0853
Echinococcus multilocularis muscleblind protein 1 0.0468 0.0897 0.0893
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0091 0.013 0.0884
Schistosoma mansoni coup transcription factor 0.0091 0.013 0.0458
Schistosoma mansoni transcription factor LCR-F1 0.0145 0.024 0.0861
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0465 0.3833
Onchocerca volvulus 0.0043 0.0032 0.0128
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0015 0.0085
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0018 0.0109
Loa Loa (eye worm) acetyltransferase 0.0147 0.0244 0.1683
Schistosoma mansoni hypothetical protein 0.0176 0.0302 0.1088
Entamoeba histolytica hypothetical protein 0.0145 0.024 0.1879
Entamoeba histolytica tubulin alpha-1 chain 0.0471 0.0901 0.7395
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0052 0.0427
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.0901 0.7427
Mycobacterium ulcerans hypothetical protein 0.0158 0.0267 0.5074
Plasmodium falciparum basic transcription factor 3b, putative 0.0076 0.0099 0.0785
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0042 0.003 0.0215
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0091 0.168
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.0234 0.1903
Leishmania major alpha tubulin 0.0471 0.0901 0.7418
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0091 0.168
Schistosoma mansoni hypothetical protein 0.1377 0.2741 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0091 0.013 0.0884
Trichomonas vaginalis tubulin, putative 0.0194 0.0339 0.2792
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0105 0.0832
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0017 0.0013
Echinococcus granulosus tumor protein p63 0.0665 0.1296 0.4719
Echinococcus granulosus tubulin alpha chain 0.0471 0.0901 0.3277
Brugia malayi Tubulin alpha-2 chain 0.0471 0.0901 0.63
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0119 0.0114
Echinococcus granulosus transcription factor Dp 1 0.004 0.0027 0.0083
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.005 0.0046 0.0348
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.1214 0.4418
Trypanosoma cruzi epsilon tubulin, putative 0.0384 0.0724 0.5953
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0088 0.0125 0.0921
Echinococcus multilocularis expressed conserved protein 0.0187 0.0324 0.032
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0043 0.0032 0.0128
Onchocerca volvulus 0.0054 0.0054 0.0317
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0256 0.0465 0.3238
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0244 0.1683
Loa Loa (eye worm) hypothetical protein 0.0048 0.0043 0.0274
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0126 0.0202 0.3813
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1126 0.9278
Schistosoma mansoni hypothetical protein 0.038 0.0716 0.2601
Loa Loa (eye worm) hypothetical protein 0.0609 0.1182 0.8268
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0088 0.0125 0.0441
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0043 0.0032 0.0028
Schistosoma mansoni alpha tubulin 0.0471 0.0901 0.3277
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0119 0.0805
Brugia malayi N-terminal motif family protein 0.0174 0.03 0.2076
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0018 0.0013
Trypanosoma cruzi transcription factor btf3, putative 0.0076 0.0099 0.0785
Loa Loa (eye worm) hypothetical protein 0.031 0.0574 0.4004
Trichomonas vaginalis tubulin alpha chain, putative 0.019 0.0332 0.2734
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0191 0.0333 0.6349
Echinococcus granulosus Tubulin alpha 1 chain 0.0471 0.0901 0.3277
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0042 0.0349
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.0901 0.7427
Loa Loa (eye worm) hypothetical protein 0.0468 0.0897 0.6267
Brugia malayi nuclear receptor RXR 0.0048 0.0043 0.0274
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0235 0.0844
Trichomonas vaginalis tubulin epsilon chain, putative 0.0471 0.0901 0.7427
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0119 0.0417
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0096
Schistosoma mansoni hypothetical protein 0.0176 0.0302 0.1088
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.0901 0.7427
Trichomonas vaginalis tubulin epsilon chain, putative 0.0625 0.1214 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0384 0.0724 0.5967
Toxoplasma gondii alpha-tubulin I, putative 0.0471 0.0901 0.7418
Brugia malayi tubulin alpha chain - mouse 0.0471 0.0901 0.63
Echinococcus multilocularis tubulin alpha chain 0.0471 0.0901 0.0897
Loa Loa (eye worm) hypothetical protein 0.0054 0.0054 0.0355
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0086 0.0082
Schistosoma mansoni hypothetical protein 0.0082 0.0112 0.0394
Echinococcus granulosus tubulin subunit TubB 0.0471 0.0901 0.3277
Loa Loa (eye worm) MH2 domain-containing protein 0.0357 0.067 0.4673
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0019 0.0106
Loa Loa (eye worm) hypothetical protein 0.0468 0.0897 0.6267
Leishmania major epsilon tubulin, putative 0.0384 0.0724 0.5953
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.033 0.0615 0.0611
Echinococcus granulosus Tubulin alpha 1 chain 0.0471 0.0901 0.3277
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0086 0.0677
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0066 0.0544
Loa Loa (eye worm) hypothetical protein 0.0326 0.0607 0.4234
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0091 0.013 0.0458
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0088 0.0728
Brugia malayi intermediate filament protein 0.0054 0.0054 0.0355
Plasmodium vivax tubulin alpha chain, putative 0.0471 0.0901 0.7418
Echinococcus granulosus GPCR family 2 0.0176 0.0302 0.1088
Entamoeba histolytica hypothetical protein 0.0145 0.024 0.1879
Onchocerca volvulus Huntingtin homolog 0.0129 0.0207 0.1626
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0091 0.013 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0079 0.0652
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0072 0.0245
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0351 0.0659 0.5413
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0086 0.0677
Echinococcus multilocularis musashi 0.0054 0.0054 0.005
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0145 0.024 0.0861
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0031 0.0223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0042 0.0349
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.0202 0.0721
Leishmania major alpha tubulin 0.0471 0.0901 0.7418
Schistosoma mansoni hypothetical protein 0.1377 0.2741 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0043 0.0032 0.0028
Trypanosoma brucei alpha tubulin 0.0471 0.0901 0.7418
Echinococcus granulosus tubulin epsilon chain 0.0384 0.0724 0.263
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1126 0.9278
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0018 0.0254
Schistosoma mansoni tubulin subunit delta 0.0161 0.0273 0.098
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1126 0.9278
Echinococcus granulosus Niemann Pick C1 protein 0.0199 0.0349 0.1258
Trichomonas vaginalis PIKK family atypical protein kinase 0.0088 0.0125 0.1031
Schistosoma mansoni alpha tubulin 0.0471 0.0901 0.3277
Brugia malayi steroid hormone receptor 0.0091 0.013 0.0884
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0091 0.168
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0088 0.0728
Trypanosoma brucei epsilon tubulin 0.0384 0.0724 0.5953
Loa Loa (eye worm) RNA binding protein 0.0062 0.0072 0.0475
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Loa Loa (eye worm) hypothetical protein 0.0709 0.1385 0.9697
Echinococcus granulosus nuclear receptor nhr 48 0.0043 0.0032 0.0102
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.0105 0.0832
Echinococcus multilocularis transcription factor eb 0.0109 0.0167 0.0162
Brugia malayi Thioredoxin reductase 0.0084 0.0115 0.0783
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1126 0.9278
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0091 0.013 0.0458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0053 0.0435
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0018 0.0254
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.004 0.0331
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.003 0.0006 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0273 0.2246
Trichomonas vaginalis importin beta-1, putative 0.0047 0.004 0.0331
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0193 0.0338 0.2758
Loa Loa (eye worm) hypothetical protein 0.0129 0.0207 0.1425
Echinococcus multilocularis transcription factor btf3 0.0076 0.0099 0.0095
Leishmania major zeta tubulin, putative 0.0498 0.0957 0.7874
Mycobacterium tuberculosis Probable dehydrogenase 0.0191 0.0333 0.6349
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0031 0.0224
Giardia lamblia Epsilon tubulin 0.0193 0.0338 0.2758
Leishmania major beta tubulin 0.0625 0.1214 1
Leishmania major beta tubulin 0.0625 0.1214 1
Trichomonas vaginalis tubulin beta chain, putative 0.019 0.0332 0.2734
Brugia malayi Isocitrate dehydrogenase 0.005 0.0046 0.0299
Brugia malayi Latrophilin receptor protein 2 0.0176 0.0302 0.2094
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0614 0.1192 0.834
Onchocerca volvulus 0.0072 0.0091 0.0634
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0062 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0042 0.0349
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.0901 0.7427
Brugia malayi Tubulin beta chain 0.019 0.0332 0.2302
Brugia malayi MH2 domain containing protein 0.0357 0.067 0.4673
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0072 0.0475
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0091 0.013 0.0125
Onchocerca volvulus 0.0043 0.0032 0.0128
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0018 0.0254
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0049 0.0853
Leishmania major importin beta-1 subunit, putative 0.0047 0.004 0.0296
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0086 0.0677
Brugia malayi hypothetical protein 0.0051 0.0048 0.0313
Leishmania major alpha tubulin 0.0471 0.0901 0.7418
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0079 0.0652
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0305 0.2512
Echinococcus granulosus tubulin subunit beta 0.0625 0.1214 0.4418
Schistosoma mansoni nuclear receptor 0.0043 0.0032 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0119 0.0977
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0043 0.0274
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0142 0.0234 0.1903
Schistosoma mansoni hypothetical protein 0.1231 0.2445 0.8917
Echinococcus granulosus tubulin beta 4A class IVa 0.0625 0.1214 0.4418
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0072 0.0475
Brugia malayi tailless protein 0.0043 0.0032 0.0201
Schistosoma mansoni zinc finger protein 0.0043 0.0032 0.0102
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0031 0.0223
Onchocerca volvulus Huntingtin homolog 0.0129 0.0207 0.1626
Echinococcus granulosus muscleblind protein 0.0468 0.0897 0.326
Echinococcus granulosus Niemann Pick C1 protein 0.0284 0.0522 0.189
Schistosoma mansoni tubulin subunit beta 0.0625 0.1214 0.4418
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0555 0.1073 0.7505
Loa Loa (eye worm) tubulin beta chain 0.0161 0.0273 0.1887
Schistosoma mansoni retinoic acid receptor RXR 0.0091 0.013 0.0458
Brugia malayi nuclear receptor RXR 0.0043 0.0032 0.0201
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.033 0.0615 0.223
Echinococcus granulosus nuclear receptor co repressor related ncor 0.0274 0.0503 0.182
Echinococcus multilocularis tubulin alpha 0.0351 0.0659 0.0655
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.0286 0.231
Plasmodium falciparum tubulin beta chain 0.0625 0.1214 1
Echinococcus granulosus lamin 0.0054 0.0054 0.0183
Plasmodium vivax tubulin gamma chain, putative 0.0384 0.0725 0.5961
Leishmania major beta tubulin 0.0625 0.1214 1
Leishmania major alpha tubulin 0.0471 0.0901 0.7418
Schistosoma mansoni thyroid hormone receptor 0.0091 0.013 0.0458
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Plasmodium falciparum tubulin gamma chain 0.0384 0.0725 0.5961
Brugia malayi hypothetical protein 0.0048 0.0043 0.0274
Echinococcus multilocularis tubulin alpha chain 0.0471 0.0901 0.0897
Trypanosoma cruzi zeta tubulin, putative 0.0498 0.0957 0.7874
Echinococcus multilocularis Tubulin alpha 1 chain 0.0471 0.0901 0.0897
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Onchocerca volvulus 0.0118 0.0186 0.1447
Brugia malayi Tubulin gamma chain 0.0384 0.0725 0.5063
Trichomonas vaginalis glutathione reductase, putative 0.0029 0.0004 0.0036
Echinococcus multilocularis tubulin alpha chain 0.0471 0.0901 0.0897
Giardia lamblia Beta tubulin 0.0625 0.1214 1
Entamoeba histolytica hypothetical protein 0.0076 0.0099 0.0705
Loa Loa (eye worm) steroid hormone receptor 0.0091 0.013 0.0884
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0088 0.0125 0.0851
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0016 0.0088
Brugia malayi nuclear receptor NHR-67 0.0043 0.0032 0.0201
Brugia malayi nuclear hormone receptor 0.0043 0.0032 0.0201
Echinococcus granulosus FTZ F1 alpha 0.0091 0.013 0.0458
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.003 0.0006 0.0001
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0043 0.0032 0.0102
Trichomonas vaginalis tubulin gamma chain, putative 0.0161 0.0273 0.2246
Trypanosoma cruzi tubulin delta chain 0.0363 0.0682 0.5601
Echinococcus granulosus peroxisome assembly protein 26 0.0471 0.0901 0.3277
Echinococcus multilocularis thioredoxin glutathione reductase 0.0084 0.0116 0.0112
Loa Loa (eye worm) hypothetical protein 0.0129 0.0207 0.1425
Schistosoma mansoni tubulin subunit beta 0.0625 0.1214 0.4418
Schistosoma mansoni nuclear receptor 0.0043 0.0032 0.0102
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0032 0.0102
Loa Loa (eye worm) hypothetical protein 0.0072 0.0091 0.0614
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.002 0.0016
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0033 0.0105
Trichomonas vaginalis tubulin epsilon chain, putative 0.0471 0.0901 0.7427
Giardia lamblia Fructose-bisphosphate aldolase 0.0581 0.1126 0.9275
Schistosoma mansoni hypothetical protein 0.0035 0.0017 0.0046
Brugia malayi Nuclear hormone receptor-like 1 0.0091 0.013 0.0884
Loa Loa (eye worm) hypothetical protein 0.0072 0.0091 0.0614
Leishmania major beta tubulin 0.0625 0.1214 1
Leishmania major alpha tubulin 0.0471 0.0901 0.7418
Loa Loa (eye worm) hypothetical protein 0.0091 0.013 0.0884
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0091 0.0614
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0286 0.236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0088 0.0125 0.1031
Schistosoma mansoni nuclear hormone receptor 0.0091 0.013 0.0458
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0018 0.0144
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.005 0.0046 0.0154
Leishmania major beta tubulin 0.0625 0.1214 1
Loa Loa (eye worm) BEN-1 protein 0.0625 0.1214 0.8492
Echinococcus multilocularis Niemann Pick C1 protein 0.0284 0.0522 0.0518
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0079 0.0652
Echinococcus granulosus tubulin alpha 3 chain 0.0471 0.0901 0.3277
Echinococcus multilocularis protein dispatched 1 0.0097 0.0143 0.0139
Brugia malayi beta-lactamase family protein 0.0035 0.0018 0.0096
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0088 0.0125 0.0998
Echinococcus multilocularis lamin 0.0054 0.0054 0.005
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.1214 0.121
Leishmania major beta tubulin 0.0625 0.1214 1
Mycobacterium tuberculosis Conserved protein 0.0035 0.0018 0.0254
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0018 0.0254
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0033 0.0238
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0033 0.0238
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0286 0.236
Loa Loa (eye worm) tubulin alpha chain 0.0471 0.0901 0.63
Echinococcus multilocularis Tubulin alpha 1 chain 0.0471 0.0901 0.0897
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0363 0.0682 0.5601
Giardia lamblia Alpha-tubulin 0.0471 0.0901 0.7418
Trypanosoma brucei tubulin delta chain 0.0363 0.0682 0.5601
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0054 0.0355
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1126 0.9278
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0191 0.0333 0.6254
Trichomonas vaginalis tubulin alpha chain, putative 0.019 0.0332 0.2734
Echinococcus multilocularis survival motor neuron protein 1 0.073 0.1428 0.1425
Echinococcus multilocularis protein patched 0.0085 0.0119 0.0114
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0018 0.0254
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0315 0.1135
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0191 0.0333 0.6349
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0191 0.0333 0.6349
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0031 0.0194
Brugia malayi tubulin alpha-2 chain 0.0471 0.0901 0.63
Loa Loa (eye worm) hypothetical protein 0.038 0.0716 0.5
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Echinococcus multilocularis isocitrate dehydrogenase 0.005 0.0046 0.0042
Echinococcus multilocularis tubulin alpha 1C chain 0.0471 0.0901 0.0897
Echinococcus granulosus beta tubulin 0.0625 0.1214 0.4418
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0032 0.0102
Loa Loa (eye worm) hypothetical protein 0.0054 0.0054 0.0355
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.1214 0.4418
Schistosoma mansoni tubulin subunit epsilon 0.0384 0.0724 0.263
Schistosoma mansoni thyroid hormone receptor 0.0091 0.013 0.0458
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0212 0.0376 0.7185
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.002 0.0057
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0018 0.0254
Schistosoma mansoni lamin 0.0054 0.0054 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0273 0.2246
Mycobacterium tuberculosis Conserved hypothetical protein 0.0158 0.0267 0.5074
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0043 0.0032 0.0028
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0315 0.2185
Echinococcus granulosus tubulin alpha 1C chain 0.0471 0.0901 0.3277
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0032 0.0102
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0091 0.013 0.0458
Toxoplasma gondii hypothetical protein 0.0049 0.0044 0.0327
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0315 0.1135
Brugia malayi photoreceptor-specific nuclear receptor 0.0326 0.0607 0.4234
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0031 0.0224
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.031 0.0574 0.4732
Leishmania major alpha tubulin 0.0471 0.0901 0.7418
Echinococcus multilocularis tubulin alpha 3 chain 0.0471 0.0901 0.0897
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0709 0.1385 0.9697
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0072 0.0245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0099 0.0815
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.0901 0.7427
Toxoplasma gondii thioredoxin reductase 0.0084 0.0115 0.0918
Onchocerca volvulus 0.019 0.0332 0.27
Plasmodium falciparum acyl-CoA synthetase 0.0054 0.0054 0.0414
Loa Loa (eye worm) glutathione reductase 0.0084 0.0115 0.0783
Schistosoma mansoni cellular tumor antigen P53 0.0097 0.0143 0.0507
Schistosoma mansoni hypothetical protein 0.0614 0.1192 0.4339
Loa Loa (eye worm) histone methyltransferase 0.0037 0.002 0.0113
Brugia malayi Muscleblind-like protein 0.0468 0.0897 0.6267
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0286 0.236
Echinococcus multilocularis expressed protein 0.0035 0.0016 0.0012
Schistosoma mansoni cpg binding protein 0.0118 0.0186 0.0664
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0091 0.013 0.0458
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0091 0.013 0.0458
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0031 0.0224
Loa Loa (eye worm) hypothetical protein 0.0079 0.0105 0.071
Brugia malayi latrophilin 2 splice variant baaae 0.038 0.0716 0.5
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0126 0.0202 0.0721
Brugia malayi conserved hypotetical protein 0.0043 0.0032 0.0201
Plasmodium vivax tubulin epsilon chain, putative 0.0384 0.0724 0.5953
Giardia lamblia Beta tubulin 0.0625 0.1214 1
Toxoplasma gondii beta tubulin 0.0625 0.1214 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.005 0.0046 0.0348
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0091 0.013 0.0458
Loa Loa (eye worm) hypothetical protein 0.0176 0.0302 0.2094
Mycobacterium ulcerans beta-lactamase 0.0035 0.0018 0.0254
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0091 0.0719
Trypanosoma cruzi zeta tubulin, putative 0.0498 0.0957 0.7874
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0033 0.0273
Giardia lamblia GTOR 0.0088 0.0125 0.0998
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0037 0.002 0.013
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.007 0.0089 0.0696
Brugia malayi hypothetical protein 0.0043 0.0032 0.0201
Trypanosoma brucei alpha tubulin 0.0471 0.0901 0.7418
Schistosoma mansoni tubulin subunit beta 0.0625 0.1214 0.4418
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0091 0.1463
Loa Loa (eye worm) tubulin beta-1 chain 0.0625 0.1214 0.8492
Echinococcus multilocularis dnaJ subfamily B 0.1231 0.2445 0.2441
Trypanosoma brucei epsilon tubulin 0.0384 0.0724 0.5953
Loa Loa (eye worm) alpha-tubulin isotype 2 0.031 0.0574 0.4004
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0091 0.1463
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0108 0.0166 0.1136
Brugia malayi CHE-14 protein 0.0085 0.0119 0.0805
Echinococcus granulosus tubulin alpha chain 0.0471 0.0901 0.3277
Schistosoma mansoni hypothetical protein 0.0145 0.024 0.0861
Trichomonas vaginalis tubulin gamma chain, putative 0.0384 0.0725 0.5975
Echinococcus granulosus tar DNA binding protein 0.0062 0.0072 0.0245
Trypanosoma brucei trypanothione reductase 0.0084 0.0115 0.0918
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.0054 0.0967
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0006 0.0047
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.005 0.0046 0.0154
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0174 0.03 0.2423
Leishmania major hypothetical protein, conserved 0.0079 0.0105 0.0832
Plasmodium falciparum tubulin epsilon chain, putative 0.0384 0.0724 0.5953
Trichomonas vaginalis tubulin beta chain, putative 0.0625 0.1214 1
Entamoeba histolytica transcription factor BTF3, putative 0.0076 0.0099 0.0705
Brugia malayi nuclear hormone receptor 0.0091 0.013 0.0884
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0031 0.0224
Brugia malayi beta-lactamase family protein 0.0035 0.0018 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0091 0.013 0.0884
Schistosoma mansoni ran 0.0042 0.0031 0.0099
Echinococcus granulosus ecdysone induced protein 78C 0.0091 0.013 0.0458
Schistosoma mansoni cpg binding protein 0.0125 0.02 0.0714
Trypanosoma cruzi beta tubulin, putative 0.0625 0.1214 1
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0465 0.3833
Plasmodium vivax thioredoxin reductase, putative 0.0084 0.0115 0.0918
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0043 0.0032 0.0128
Plasmodium falciparum alpha tubulin 2 0.0471 0.0901 0.7418
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0086 0.0579
Loa Loa (eye worm) hypothetical protein 0.0054 0.0054 0.0355
Leishmania major phosphatidylinositol 3-related kinase, putative 0.003 0.0006 0.0011
Trypanosoma brucei alpha tubulin 0.0471 0.0901 0.7418
Schistosoma mansoni hypothetical protein 0.0082 0.0112 0.0394
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0018 0.0254
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.1214 0.4418
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0099 0.0818
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0199 0.0349 0.2786
Loa Loa (eye worm) tubulin alpha 2 0.031 0.0574 0.4004
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0018 0.0109
Echinococcus granulosus transcription factor btf3 0.0076 0.0099 0.0347
Brugia malayi hypothetical protein 0.0048 0.0043 0.0274
Loa Loa (eye worm) hypothetical protein 0.0174 0.03 0.2076
Brugia malayi Tubulin beta chain 0.0161 0.0273 0.1887
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0031 0.0223
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0054 0.0355
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0161 0.0273 0.2246
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0046 0.0042
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0161 0.0273 1
Trypanosoma brucei beta tubulin 0.0351 0.0659 0.5413
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0048 0.0043 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0062 0.0512
Trichomonas vaginalis PIKK family atypical protein kinase 0.0088 0.0125 0.1031
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0043 0.0274
Toxoplasma gondii isocitrate dehydrogenase 0.005 0.0046 0.0348
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0251 0.0456 0.1649
Schistosoma mansoni rotamase 0.0035 0.0016 0.0044
Leishmania major beta tubulin 0.0625 0.1214 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0581 0.1126 0.9269
Leishmania major beta tubulin 0.0625 0.1214 1
Loa Loa (eye worm) beta-tubulin 0.0625 0.1214 0.8492
Leishmania major alpha tubulin 0.0471 0.0901 0.7418
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.003 0.0006 0.0011
Loa Loa (eye worm) nuclear hormone receptor 0.0043 0.0032 0.0201
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.0234 0.1903
Leishmania major delta tubulin, putative 0.0363 0.0682 0.5601
Brugia malayi hypothetical protein 0.0609 0.1182 0.8268
Loa Loa (eye worm) transcription factor SMAD2 0.0357 0.067 0.4673
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0105 0.0832
Schistosoma mansoni transcription factor btf3 0.0076 0.0099 0.0347
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0088 0.0125 0.0121
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0149 0.0248 0.1714
Loa Loa (eye worm) BEN-1 protein 0.0625 0.1214 0.8492
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.005 0.0046 0.0042
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0072 0.0091 0.168
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0126 0.0202 0.0197
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0315 0.1135
Leishmania major gamma-tubulin 0.0384 0.0725 0.5961
Echinococcus granulosus transcription factor eb 0.0109 0.0167 0.0593
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0091 0.013 0.0884
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0043 0.0032 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0091 0.013 0.0884
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0176 0.0302 0.1088
Echinococcus multilocularis cpg binding protein 0.0125 0.02 0.0195
Echinococcus multilocularis Tubulin alpha 1 chain 0.0471 0.0901 0.0897
Echinococcus granulosus cpg binding protein 0.0125 0.02 0.0714
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Onchocerca volvulus 0.0054 0.0054 0.0317
Loa Loa (eye worm) nuclear receptor NHR-67 0.0043 0.0032 0.0201
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0305 0.2512
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0015 0.0085
Plasmodium vivax delta tubulin, putative 0.0161 0.0273 0.2218
Trypanosoma brucei zeta tubulin, putative 0.0498 0.0957 0.7874
Brugia malayi alpha-tubulin 0.0471 0.0901 0.63
Plasmodium falciparum alpha tubulin 1 0.0471 0.0901 0.7418
Mycobacterium tuberculosis Cell division protein FtsZ 0.0161 0.0273 0.518
Leishmania major mitochondrial DNA polymerase beta 0.0301 0.0556 0.4562
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.004 0.0331
Brugia malayi Tubulin alpha chain 0.0471 0.0901 0.63
Mycobacterium ulcerans hypothetical protein 0.0035 0.0018 0.0254
Loa Loa (eye worm) hypothetical protein 0.073 0.1428 1
Brugia malayi beta-tubulin, identical 0.0625 0.1214 0.8492
Echinococcus multilocularis tubulin epsilon chain 0.0384 0.0724 0.072
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.005 0.0046 0.0812
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0046 0.0348
Trypanosoma cruzi tubulin delta chain 0.0363 0.0682 0.5601
Echinococcus multilocularis tubulin alpha chain 0.0471 0.0901 0.0897
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0026 0.0178
Giardia lamblia Gamma tubulin 0.0384 0.0725 0.5961
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0018 0.0109
Brugia malayi Nuclear hormone receptor E75 0.0043 0.0032 0.0201
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0202 0.0355 0.1281
Brugia malayi Niemann-Pick C1 protein precursor 0.0199 0.0349 0.242
Giardia lamblia Alpha-tubulin 0.0471 0.0901 0.7418
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0006 0.0011
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0091 0.0719
Echinococcus multilocularis tubulin gamma 1 chain 0.0384 0.0725 0.0721
Trichomonas vaginalis mercuric reductase, putative 0.0029 0.0004 0.0036
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0054 0.0054 0.0967
Leishmania major beta tubulin 0.0625 0.1214 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0191 0.0333 0.6349
Echinococcus multilocularis microtubule associated protein 2 0.1359 0.2704 0.27
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0301 0.0556 0.4562
Loa Loa (eye worm) thioredoxin reductase 0.0084 0.0115 0.0783
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0091 0.013 0.0125
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.1214 0.121
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0018 0.0109
Trypanosoma cruzi epsilon tubulin, putative 0.0384 0.0724 0.5953
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.003 0.0006 0.0005
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0091 0.013 0.0125
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0301 0.0556 0.4562
Schistosoma mansoni survival motor neuron protein 0.0149 0.0248 0.089
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0091 0.013 0.0458
Toxoplasma gondii beta-1 tubulin, putative 0.0625 0.1214 1
Trichomonas vaginalis rotamase, putative 0.0035 0.0016 0.0135
Trypanosoma brucei alpha tubulin, putative 0.019 0.0332 0.2708
Echinococcus multilocularis hypothetical protein 0.0471 0.0901 0.0897
Loa Loa (eye worm) hypothetical protein 0.0104 0.0157 0.1078
Schistosoma mansoni steroid hormone receptor ad4bp 0.0091 0.013 0.0458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0042 0.035
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0088 0.0125 0.0998
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0091 0.013 0.0884
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0018 0.0096
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0048 0.0043 0.0274
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0091 0.013 0.0458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0042 0.035
Toxoplasma gondii NAC domain-containing protein 0.0076 0.0099 0.0785
Brugia malayi isocitrate dehydrogenase 0.005 0.0046 0.0299
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0286 0.236
Trypanosoma cruzi target of rapamycin kinase 3 0.007 0.0089 0.0696
Plasmodium vivax acyl-CoA synthetase, putative 0.0054 0.0054 0.0414
Schistosoma mansoni hypothetical protein 0.0176 0.0302 0.1088
Loa Loa (eye worm) hypothetical protein 0.0053 0.0052 0.0341
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0049 0.0853
Mycobacterium leprae cell division protein FtsZ 0.0161 0.0273 0.5055
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0031 0.0224
Trypanosoma brucei tubulin gamma chain 0.0384 0.0725 0.5961
Trypanosoma brucei alpha tubulin 0.0471 0.0901 0.7418
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.004 0.0296
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0202 0.3813
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0091 0.013 0.0884
Echinococcus multilocularis peroxisome assembly protein 26 0.0471 0.0901 0.0897
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.1214 0.4418
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0006 0.0047
Plasmodium falciparum thioredoxin reductase 0.0084 0.0115 0.0918
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0006 0.0047
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0315 0.0311
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0091 0.013 0.0884
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0072 0.0067
Plasmodium vivax importin-beta 2, putative 0.0058 0.0062 0.0479
Entamoeba histolytica Ran family GTPase 0.0042 0.0031 0.014
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0212 0.0376 0.7185
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0018 0.0096
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0026 0.0178
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0091 0.013 0.0884
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0018 0.0048
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0091 0.013 0.0458
Schistosoma mansoni microtubule-associated protein tau 0.1359 0.2704 0.9863
Loa Loa (eye worm) hypothetical protein 0.0091 0.013 0.0884
Leishmania major beta tubulin 0.0625 0.1214 1
Echinococcus multilocularis beta tubulin 0.0625 0.1214 0.121
Leishmania major beta tubulin 0.0625 0.1214 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0176 0.0302 0.0298
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0015 0.0085
Echinococcus granulosus alpha tubulin 0.0471 0.0901 0.3277
Schistosoma mansoni hypothetical protein 0.0082 0.0112 0.0394
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0046 0.0042
Leishmania major GTP-binding protein, putative 0.0042 0.0031 0.0224
Schistosoma mansoni hypothetical protein 0.0082 0.0112 0.0394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0079 0.0652
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0202 0.3813
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0072 0.0091 0.168
Entamoeba histolytica hypothetical protein 0.0047 0.004 0.0213
Trypanosoma cruzi alpha tubulin, putative 0.0471 0.0901 0.7418
Echinococcus granulosus tubulin alpha chain 0.0471 0.0901 0.3277
Brugia malayi glutathione reductase 0.0084 0.0115 0.0783
Brugia malayi TAR-binding protein 0.0062 0.0072 0.0475
Trypanosoma brucei target of rapamycin kinase 3, putative 0.007 0.0089 0.0696
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0091 0.168
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0202 0.3813
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0091 0.013 0.0884
Brugia malayi Nuclear hormone receptor E75 0.0043 0.0032 0.0201
Brugia malayi beta-lactamase 0.0035 0.0018 0.0096
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0465 0.3833
Leishmania major beta tubulin 0.0625 0.1214 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0315 0.2185
Entamoeba histolytica tubulin alpha chain, putative 0.0471 0.0901 0.7395
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0042 0.035
Echinococcus multilocularis ecdysone induced protein 78C 0.0091 0.013 0.0125
Plasmodium vivax tubulin alpha chain, putative 0.0471 0.0901 0.7418
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0244 0.0239
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0062 0.0479
Echinococcus multilocularis tubulin alpha chain 0.0471 0.0901 0.0897
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0033 0.0273
Echinococcus multilocularis thyroid hormone receptor alpha 0.0091 0.013 0.0125
Leishmania major beta tubulin 0.0625 0.1214 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0281 0.0515 0.4244
Echinococcus granulosus microtubule associated protein 2 0.1359 0.2704 0.9863
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Brugia malayi Tubulin beta-1 chain 0.0625 0.1214 0.8492
Echinococcus granulosus Tubulin beta 2C chain 0.0625 0.1214 0.4418
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1126 0.9278
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0088 0.0728
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0006 0.0013
Schistosoma mansoni intermediate filament proteins 0.0054 0.0054 0.0183
Schistosoma mansoni tubulin subunit alpha 0.0471 0.0901 0.3277
Echinococcus granulosus tubulin beta 1 chain 0.0625 0.1214 0.4418
Echinococcus multilocularis tubulin alpha 3 chain 0.0471 0.0901 0.0897
Leishmania major beta tubulin 0.0625 0.1214 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.013 0.0884
Schistosoma mansoni tubulin subunit beta 0.0625 0.1214 0.4418
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.005 0.0046 0.0348
Trypanosoma brucei beta tubulin 0.0625 0.1214 1
Trichomonas vaginalis tubulin alpha chain, putative 0.019 0.0332 0.2734
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0315 0.0311
Brugia malayi Importin beta-1 subunit 0.0058 0.0062 0.041
Leishmania major phosphatidylinositol 3-kinase, putative 0.003 0.0006 0.0011
Echinococcus granulosus thyroid hormone receptor alpha 0.0043 0.0032 0.0102
Plasmodium vivax glutathione reductase, putative 0.0084 0.0115 0.0918
Brugia malayi hypothetical protein 0.0043 0.0032 0.0201
Plasmodium vivax basic transcription factor 3b, putative 0.0076 0.0099 0.0785
Schistosoma mansoni tubulin subunit gamma 0.0384 0.0725 0.2634
Loa Loa (eye worm) hypothetical protein 0.0085 0.0119 0.0805
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0091 0.013 0.0884
Loa Loa (eye worm) hypothetical protein 0.0048 0.0043 0.0274
Trypanosoma brucei epsilon tubulin 0.0351 0.0659 0.5413
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.1214 0.121
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0256 0.0465 0.3238
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0091 0.013 0.0884
Brugia malayi nuclear hormone receptor family member nhr-6 0.0043 0.0032 0.0201
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0046 0.0348
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0018 0.0048
Entamoeba histolytica tubulin gamma chain 0.0384 0.0725 0.5926
Loa Loa (eye worm) CXXC zinc finger family protein 0.0118 0.0186 0.1279
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0105 0.0832
Schistosoma mansoni hypothetical protein 0.0149 0.0248 0.089
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0088 0.0728
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0084 0.0115 0.2145
Echinococcus granulosus geminin 0.1377 0.2741 1
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0465 0.3833
Trichomonas vaginalis tubulin, putative 0.0625 0.1214 1
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0286 0.236
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.0105 0.0832
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0016 0.0135
Loa Loa (eye worm) hypothetical protein 0.0091 0.013 0.0884
Mycobacterium tuberculosis Probable reductase 0.0191 0.0333 0.6349
Echinococcus granulosus tubulin alpha chain 0.0471 0.0901 0.3277
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0091 0.0719
Entamoeba histolytica acyl-coA synthetase, putative 0.0072 0.0091 0.0639
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0072 0.0245
Echinococcus multilocularis nuclear receptor co repressor related (ncor) 0.0274 0.0503 0.0498
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.0901 0.7427
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0032 0.0028
Brugia malayi ecdysteroid receptor 0.0091 0.013 0.0884
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0086 0.0579
Mycobacterium tuberculosis Conserved protein 0.0035 0.0018 0.0254
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0096
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0091 0.013 0.0884
Schistosoma mansoni cpg binding protein 0.0125 0.02 0.0714
Leishmania major beta tubulin 0.0625 0.1214 1
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0286 0.236
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0091 0.0639
Loa Loa (eye worm) tubulin alpha 2 0.031 0.0574 0.4004
Brugia malayi Calcitonin receptor-like protein seb-1 0.0555 0.1073 0.7505
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0091 0.013 0.0884
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0096
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0048 0.0043 0.0141
Brugia malayi beta-NAC-like protein 0.0076 0.0099 0.067
Brugia malayi Tubulin alpha chain 0.0161 0.0273 0.1887
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0091 0.013 0.0964
Trichomonas vaginalis tubulin gamma chain, putative 0.0625 0.1214 1
Leishmania major alpha tubulin 0.0471 0.0901 0.7418
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0026 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0052 0.0427
Brugia malayi Cell division protein ftsZ 0.0161 0.0273 0.1887
Brugia malayi Steroid receptor seven-up type 2 0.0091 0.013 0.0884
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.1136
Leishmania major basic transcription factor 3a, putative 0.0076 0.0099 0.0785
Toxoplasma gondii beta-tubulin, putative 0.0625 0.1214 1
Brugia malayi hypothetical protein 0.073 0.1428 1
Echinococcus granulosus survival motor neuron protein 1 0.073 0.1428 0.5203
Echinococcus multilocularis tubulin beta 1 chain 0.0625 0.1214 0.121
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0086 0.0299
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0072 0.0245
Schistosoma mansoni tubulin subunit beta 0.0625 0.1214 0.4418
Echinococcus multilocularis tubulin subunit beta 0.0625 0.1214 0.121
Echinococcus multilocularis Niemann Pick C1 protein 0.0199 0.0349 0.0344
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0109 0.0167 0.1144
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Giardia lamblia Beta tubulin 0.0625 0.1214 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0161 0.0273 0.2246
Loa Loa (eye worm) latrophilin receptor protein 2 0.0176 0.0302 0.2094
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0031 0.0224
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0017 0.0046
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0091 0.013 0.0458
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0048 0.0043 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0006 0.0047
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0054 0.0355
Brugia malayi hypothetical protein 0.0079 0.0105 0.071
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0015 0.0085
Trichomonas vaginalis ran, putative 0.0042 0.0031 0.0259
Schistosoma mansoni tubulin subunit alpha 0.0161 0.0273 0.098
Brugia malayi nuclear hormone receptor family member odr-7 0.0043 0.0032 0.0201
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0086 0.0597
Onchocerca volvulus 0.0091 0.013 0.0964
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0033 0.0238
Mycobacterium ulcerans lipase LipD 0.0035 0.0018 0.0254
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0088 0.0125 0.0998
Loa Loa (eye worm) hypothetical protein 0.0054 0.0054 0.0355
Toxoplasma gondii target of rapamycin (TOR), putative 0.0066 0.0079 0.0618
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0018 0.0048
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0284 0.0522 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0046 0.0042
Echinococcus granulosus lamin dm0 0.0054 0.0054 0.0183
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0079 0.0652
Loa Loa (eye worm) hypothetical protein 0.0054 0.0054 0.0355
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0054 0.0054 1
Schistosoma mansoni tubulin subunit beta 0.0625 0.1214 0.4418
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0091 0.013 0.0884
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0091 0.0639
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0048 0.0043 0.0274
Trypanosoma brucei transcription factor BTF3, putative 0.0076 0.0099 0.0785
Leishmania major alpha tubulin 0.0471 0.0901 0.7418
Echinococcus granulosus intermediate filament protein 0.0054 0.0054 0.0183
Brugia malayi nuclear receptor NHR-88 0.0043 0.0032 0.0201
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0088 0.0125 0.0921
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0096
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0072 0.0091 0.168
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0031 0.0223
Entamoeba histolytica hypothetical protein 0.0145 0.024 0.1879
Loa Loa (eye worm) hypothetical protein 0.0072 0.0091 0.0614
Loa Loa (eye worm) phosphatidylinositol 3 0.0088 0.0125 0.0851
Trypanosoma cruzi transcription factor btf3, putative 0.0076 0.0099 0.0785
Plasmodium falciparum importin beta, putative 0.0058 0.0062 0.0479
Entamoeba histolytica tubulin family protein 0.0625 0.1214 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0091 0.013 0.0884
Entamoeba histolytica hypothetical protein 0.0145 0.024 0.1879
Leishmania major alpha tubulin 0.0471 0.0901 0.7418
Treponema pallidum fructose-bisphosphate aldolase 0.0581 0.1126 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0228 0.0408 0.3342
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0244 0.0874
Loa Loa (eye worm) alpha-tubulin 0.0471 0.0901 0.63
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0315 0.1135
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0581 0.1126 0.9269
Mycobacterium tuberculosis Conserved protein 0.0035 0.0018 0.0254
Brugia malayi orphan nuclear receptor NR2E1 0.0043 0.0032 0.0201
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0315 0.1135
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0091 0.013 0.0884
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0018 0.0144
Leishmania major alpha tubulin 0.0471 0.0901 0.7418
Toxoplasma gondii alpha tubulin TUBA1 0.0471 0.0901 0.7418
Schistosoma mansoni RAR-like nuclear receptor 0.0091 0.013 0.0458
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0088 0.0125 0.0998
Echinococcus granulosus tubulin alpha chain 0.0471 0.0901 0.3277
Leishmania major hypothetical protein, conserved 0.0035 0.0018 0.0109
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0212 0.0376 0.7111
Loa Loa (eye worm) hypothetical protein 0.0471 0.0901 0.63
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0018 0.0144
Loa Loa (eye worm) hypothetical protein 0.0054 0.0054 0.0355
Loa Loa (eye worm) hypothetical protein 0.0097 0.0143 0.0978
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0126 0.0202 0.1633
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1126 0.9278
Toxoplasma gondii ABC1 family protein 0.0035 0.0018 0.0109
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0301 0.0556 0.4562
Echinococcus granulosus tubulin delta chain 0.0161 0.0273 0.098
Schistosoma mansoni patched 1 0.0085 0.0119 0.0417
Onchocerca volvulus 0.0149 0.0248 0.1979
Loa Loa (eye worm) hypothetical protein 0.0091 0.013 0.0884
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0018 0.0254
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0079 0.0652
Loa Loa (eye worm) hypothetical protein 0.0043 0.0032 0.0201
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0046 0.0348
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0091 0.013 0.0458
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.0202 0.0721
Brugia malayi nuclear receptor NHR-88 0.0091 0.013 0.0884
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.019 0.0332 0.2734
Plasmodium falciparum glutathione reductase 0.0084 0.0115 0.0918
Leishmania major alpha tubulin 0.0471 0.0901 0.7418
Echinococcus granulosus tubulin alpha 1C chain 0.0471 0.0901 0.3277
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0053 0.0435
Toxoplasma gondii tubulin, putative 0.0032 0.0011 0.0053
Mycobacterium ulcerans hypothetical protein 0.0072 0.0091 0.168
Echinococcus granulosus Nuclear hormone receptor HR96 0.0043 0.0032 0.0102
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.003 0.0006 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0006 0.0047
Loa Loa (eye worm) tubulin alpha 2 0.0119 0.0188 0.1292
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0091 0.013 0.0125
Brugia malayi Tubulin alpha-2 chain 0.0471 0.0901 0.63
Loa Loa (eye worm) hypothetical protein 0.0281 0.0515 0.3588
Loa Loa (eye worm) tubulin beta chain 0.0625 0.1214 0.8492
Loa Loa (eye worm) hypothetical protein 0.0091 0.013 0.0884
Trypanosoma brucei beta tubulin 0.0625 0.1214 1
Echinococcus granulosus expressed conserved protein 0.0187 0.0324 0.1169
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0465 0.3833
Brugia malayi RNA, U transporter 1 0.0164 0.0278 0.1921
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0091 0.013 0.0458
Loa Loa (eye worm) ICD-1 protein 0.0076 0.0099 0.067
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0086 0.0677
Leishmania major beta tubulin 0.0625 0.1214 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0018 0.0144
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.0105 0.0832
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0049 0.0853
Plasmodium falciparum tubulin delta chain, putative 0.0161 0.0273 0.2218
Echinococcus multilocularis Tubulin beta 2C chain 0.0625 0.1214 0.121
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0016 0.0088

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Targets
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 26882  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 26953  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 29919  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 25756  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 29777  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 25113  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 29099  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 28601  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 24472  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 21739  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 28044  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 21309  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 24440  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 20919  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 22594  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 23453  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 21545  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 29554  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 29031  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 23905  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 21179  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 25450  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 22205  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 27459  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 26961  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 22252  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 23996  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 23078  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 20827  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 28024  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) promastigote (BTO:0001124) inferred from bioassay (ECO:0000094) Leishmania donovani 28324  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 26882  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 26953  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 29919  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 25756  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 29777  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 25113  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 29099  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 28601  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 24472  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 21739  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 28044  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 21309  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 24440  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 20919  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 22594  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 23453  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 21545  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 29554  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 29031  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 23905  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 21179  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 25450  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 22205  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 27459  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 26961  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 22252  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 23996  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 23078  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 20827  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 28024  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
growth (GO:0040007) decreased time (PATO:0000716) single cell organism (CARO:0000064) amastigote (BTO:0000062) inferred from bioassay (ECO:0000094) Leishmania donovani 28324  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 26882  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 26953  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 29919  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 25756  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 29777  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 25113  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 29099  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 28601  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 24472  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 21739  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 28044  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 21309  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 24440  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 20919  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 22594  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 23453  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 21545  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 29554  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 29031  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 23905  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 21179  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 25450  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 22205  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 27459  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 26961  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 22252  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 23996  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 23078  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 20827  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 28024  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141
microtubule polymerization (GO:0046785) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 28324  
Annotator: aaronjr@u.washington.edu Comment: Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied References: 12161141

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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Bibliographic References

7 literature references were collected for this gene.

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