Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | lipase LipD | 0.0149 | 0.1407 | 0.2421 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0035 | 0.0189 | 0.1341 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0149 | 0.1407 | 0.1377 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0035 | 0.0189 | 0.1341 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0107 | 0.0758 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0798 | 0.1399 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0528 | 0.3592 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0491 | 0.5071 | 0.9251 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0189 | 0.1341 |
Mycobacterium ulcerans | hypothetical protein | 0.0149 | 0.1407 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1407 | 0.2467 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0355 | 0.3617 | 0.6343 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0528 | 0.2905 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0024 | 0.0066 | 0.2049 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0101 | 0.0899 | 0.0867 |
Onchocerca volvulus | 0.0149 | 0.1407 | 1 | |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0189 | 0.1039 |
Brugia malayi | hypothetical protein | 0.0128 | 0.1186 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0424 | 0.0743 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.0035 | 0.0061 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0528 | 0.375 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0024 | 0.0075 | 0.0136 |
Schistosoma mansoni | hypothetical protein | 0.0529 | 0.5481 | 0.9612 |
Echinococcus granulosus | geminin | 0.0529 | 0.5481 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0035 | 0.0189 | 0.1341 |
Schistosoma mansoni | tar DNA-binding protein | 0.0277 | 0.278 | 0.4875 |
Plasmodium falciparum | glutathione reductase | 0.0101 | 0.0899 | 1 |
Loa Loa (eye worm) | inositol-1 | 0.0078 | 0.0646 | 0.1134 |
Schistosoma mansoni | tar DNA-binding protein | 0.0277 | 0.278 | 0.4875 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0149 | 0.1407 | 0.2567 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0201 | 0.1109 |
Schistosoma mansoni | inositol monophosphatase | 0.0078 | 0.0646 | 0.1134 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0035 | 0.0189 | 0.0331 |
Schistosoma mansoni | alpha-glucosidase | 0.0141 | 0.1321 | 0.2317 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0149 | 0.1407 | 0.2421 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0201 | 0.0353 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0035 | 0.0189 | 0.5 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0035 | 0.0387 |
Trichomonas vaginalis | ran, putative | 0.0024 | 0.0075 | 0.0131 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0066 | 0.023 |
Mycobacterium tuberculosis | Probable reductase | 0.0231 | 0.229 | 0.2263 |
Echinococcus multilocularis | tar DNA binding protein | 0.0277 | 0.278 | 0.5071 |
Plasmodium vivax | importin-beta 2, putative | 0.0033 | 0.0169 | 0.1199 |
Treponema pallidum | NADH oxidase | 0.0035 | 0.0189 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0491 | 0.5071 | 0.9251 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0107 | 0.0587 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0491 | 0.5071 | 0.9251 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0107 | 0.0187 |
Echinococcus granulosus | tumor protein p63 | 0.039 | 0.3989 | 0.7277 |
Toxoplasma gondii | ABC1 family protein | 0.0149 | 0.1407 | 0.7748 |
Leishmania major | trypanothione reductase | 0.0101 | 0.0899 | 0.4948 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0035 | 0.0189 | 0.0154 |
Onchocerca volvulus | 0.0149 | 0.1407 | 1 | |
Onchocerca volvulus | 0.0149 | 0.1407 | 1 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0277 | 0.278 | 0.4875 |
Loa Loa (eye worm) | glutaminase | 0.055 | 0.5702 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0529 | 0.5481 | 0.9612 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0231 | 0.229 | 0.2263 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0075 | 0.0131 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0187 | 0.1816 | 0.3184 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.1026 | 1 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0024 | 0.0066 | 0.0121 |
Schistosoma mansoni | glutaminase | 0.055 | 0.5702 | 1 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0035 | 0.0189 | 0.0272 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0024 | 0.0066 | 0.0116 |
Echinococcus granulosus | neuropeptide s receptor | 0.0491 | 0.5071 | 0.9251 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0201 | 0.1962 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0201 | 0.0367 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0035 | 0.0189 | 0.0344 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0078 | 0.0646 | 0.4458 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0078 | 0.0646 | 0.1134 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0231 | 0.229 | 0.2263 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0149 | 0.1407 | 1 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0024 | 0.0066 | 0.0116 |
Trichomonas vaginalis | importin beta-1, putative | 0.0027 | 0.0101 | 0.0178 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0201 | 0.0353 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0026 | 0.0089 | 0.0156 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0035 | 0.0061 |
Plasmodium vivax | hypothetical protein, conserved | 0.0149 | 0.1407 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0149 | 0.1407 | 0.1377 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0187 | 0.1816 | 0.3313 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0035 | 0.0189 | 0.1122 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0113 | 0.1026 | 0.18 |
Loa Loa (eye worm) | TAR-binding protein | 0.0277 | 0.278 | 0.4875 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0066 | 0.0116 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0231 | 0.229 | 0.2263 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0035 | 0.0189 | 0.1039 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0107 | 0.0587 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0066 | 0.0116 |
Schistosoma mansoni | lamin | 0.0027 | 0.01 | 0.0176 |
Mycobacterium leprae | conserved hypothetical protein | 0.0149 | 0.1407 | 0.4223 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0061 | 0.0465 | 0.3309 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0066 | 0.0116 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0035 | 0.0189 | 1 |
Brugia malayi | RNA, U transporter 1 | 0.0095 | 0.0826 | 0.1448 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0075 | 0.053 |
Trichomonas vaginalis | esterase, putative | 0.0149 | 0.1407 | 0.2467 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.007 | 0.0563 | 0.1027 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.01 | 0.0176 |
Brugia malayi | glutathione reductase | 0.0101 | 0.0899 | 0.1576 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0092 | 0.0798 | 0.1456 |
Plasmodium falciparum | glutathione reductase | 0.0035 | 0.0189 | 0.21 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0201 | 0.1109 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0187 | 0.1816 | 0.1787 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.01 | 0.0176 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0149 | 0.1407 | 0.1377 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0027 | 0.0101 | 0.072 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0528 | 0.2905 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0078 | 0.0646 | 0.1179 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0257 | 0.2567 | 0.2541 |
Onchocerca volvulus | 0.0027 | 0.01 | 0.0713 | |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.01 | 0.0183 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0201 | 0.1431 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0164 | 0.1565 | 0.2856 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0107 | 0.1187 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.007 | 0.0563 | 0.31 |
Echinococcus multilocularis | geminin | 0.0529 | 0.5481 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0101 | 0.0899 | 0.1576 |
Schistosoma mansoni | inositol monophosphatase | 0.0078 | 0.0646 | 0.1134 |
Onchocerca volvulus | Huntingtin homolog | 0.0128 | 0.1186 | 0.8429 |
Mycobacterium tuberculosis | Conserved protein | 0.0149 | 0.1407 | 0.1377 |
Leishmania major | hypothetical protein, conserved | 0.0149 | 0.1407 | 0.7748 |
Onchocerca volvulus | 0.0027 | 0.01 | 0.0713 | |
Echinococcus multilocularis | musashi | 0.0027 | 0.01 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1407 | 0.2467 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.01 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1407 | 0.2467 |
Schistosoma mansoni | hypothetical protein | 0.0355 | 0.3617 | 0.6343 |
Echinococcus granulosus | importin subunit beta 1 | 0.0033 | 0.0169 | 0.0308 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0078 | 0.0646 | 0.1134 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0033 | 0.0169 | 0.0976 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0066 | 0.0365 |
Echinococcus multilocularis | snurportin 1 | 0.0355 | 0.3617 | 0.6598 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0189 | 0.1341 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0021 | 0.0035 | 0.0191 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0033 | 0.0169 | 0.0976 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0149 | 0.1407 | 0.1377 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0149 | 0.1407 | 0.2567 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.01 | 0.0176 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0002 | 0.0004 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.007 | 0.0563 | 0.0987 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0149 | 0.1407 | 0.2421 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0024 | 0.0075 | 0.053 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0231 | 0.229 | 0.2263 |
Schistosoma mansoni | importin beta-1 | 0.0033 | 0.0169 | 0.0296 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0149 | 0.1407 | 0.2467 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0149 | 0.1407 | 0.2467 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0107 | 0.0524 |
Toxoplasma gondii | exonuclease III APE | 0.0021 | 0.0035 | 0.0191 |
Mycobacterium tuberculosis | Conserved protein | 0.0149 | 0.1407 | 0.1377 |
Brugia malayi | beta-lactamase | 0.0149 | 0.1407 | 0.2467 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0101 | 0.0899 | 0.1639 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0187 | 0.1816 | 0.3184 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0201 | 0.0353 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0528 | 0.3592 |
Loa Loa (eye worm) | glutaminase 2 | 0.055 | 0.5702 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0528 | 0.375 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0024 | 0.0066 | 0.0365 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.007 | 0.0563 | 0.1027 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0026 | 0.0089 | 0.0156 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0528 | 0.3592 |
Echinococcus granulosus | tar DNA binding protein | 0.0277 | 0.278 | 0.5071 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0092 | 0.0798 | 0.1399 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0024 | 0.0066 | 0.0646 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0075 | 0.083 |
Echinococcus multilocularis | lamin | 0.0027 | 0.01 | 0.0183 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0024 | 0.0066 | 0.0121 |
Trypanosoma brucei | trypanothione reductase | 0.0101 | 0.0899 | 0.6295 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0078 | 0.0646 | 0.1134 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0113 | 0.1026 | 0.1872 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.0035 | 0.0061 |
Schistosoma mansoni | ran | 0.0024 | 0.0075 | 0.0131 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0024 | 0.0075 | 0.0411 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0257 | 0.2567 | 1 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0021 | 0.0035 | 0.0339 |
Plasmodium falciparum | thioredoxin reductase | 0.0101 | 0.0899 | 1 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0024 | 0.0066 | 0.0471 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0078 | 0.0646 | 0.4595 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0035 | 0.0189 | 0.1039 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.007 | 0.0563 | 0.3849 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0078 | 0.0646 | 0.4595 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0035 | 0.0061 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0021 | 0.0035 | 0.0247 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0024 | 0.0075 | 0.0136 |
Brugia malayi | beta-lactamase family protein | 0.0149 | 0.1407 | 0.2467 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0035 | 0.0189 | 0.1341 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0201 | 0.0353 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0149 | 0.1407 | 0.2467 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0035 | 0.0189 | 0.1122 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0107 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0169 | 0.0296 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0057 | 0.0424 | 0.0743 |
Schistosoma mansoni | alpha-glucosidase | 0.0141 | 0.1321 | 0.2317 |
Toxoplasma gondii | thioredoxin reductase | 0.0101 | 0.0899 | 0.4948 |
Plasmodium falciparum | importin beta, putative | 0.0033 | 0.0169 | 0.1877 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.0035 | 0.0063 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0189 | 0.1341 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1407 | 0.2467 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.0035 | 0.0061 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0035 | 0.0189 | 0.1039 |
Brugia malayi | glutaminase DH11.1 | 0.055 | 0.5702 | 1 |
Mycobacterium ulcerans | glutaminase | 0.055 | 0.5702 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0201 | 0.0353 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0027 | 0.0101 | 0.0178 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0201 | 0.0353 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0041 | 0.0247 | 0.045 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0066 | 0.0116 |
Leishmania major | GTP-binding protein, putative | 0.0024 | 0.0075 | 0.0411 |
Brugia malayi | Inositol-1 | 0.0078 | 0.0646 | 0.1134 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0201 | 0.0353 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0528 | 0.3592 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.1186 | 0.208 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0149 | 0.1407 | 1 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0078 | 0.0646 | 1 |
Onchocerca volvulus | 0.0095 | 0.0826 | 0.5873 | |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0189 | 0.1341 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0033 | 0.0169 | 0.0929 |
Brugia malayi | TAR-binding protein | 0.0277 | 0.278 | 0.4875 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0075 | 0.0131 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0041 | 0.0247 | 0.045 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.01 | 0.0176 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.1026 | 0.18 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0113 | 0.1026 | 0.1872 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0035 | 0.0189 | 0.2517 |
Brugia malayi | hypothetical protein | 0.0113 | 0.1026 | 0.18 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.1026 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0035 | 0.0189 | 0.0331 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0092 | 0.0798 | 0.1456 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0035 | 0.0189 | 0.1122 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0149 | 0.1407 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0277 | 0.278 | 0.4875 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0078 | 0.0646 | 0.1079 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0033 | 0.0169 | 0.0308 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0078 | 0.0646 | 0.356 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0187 | 0.1816 | 0.3143 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0075 | 0.2586 |
Plasmodium falciparum | thioredoxin reductase | 0.0035 | 0.0189 | 0.21 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0164 | 0.1565 | 0.2856 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0231 | 0.229 | 0.2263 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.01 | 0.0176 |
Leishmania major | importin beta-1 subunit, putative | 0.0027 | 0.0101 | 0.0558 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0035 | 0.0189 | 0.0344 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0078 | 0.0646 | 0.6299 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0149 | 0.1407 | 0.1377 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0092 | 0.0798 | 0.1456 |
Plasmodium vivax | glutathione reductase, putative | 0.0101 | 0.0899 | 0.6387 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0187 | 0.1816 | 0.3313 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0528 | 0.3592 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.007 | 0.0563 | 0.5485 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0035 | 0.0189 | 0.0272 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0035 | 0.0189 | 0.0331 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0067 | 0.0528 | 0.375 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0149 | 0.1407 | 0.2467 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0164 | 0.1565 | 0.2745 |
Mycobacterium ulcerans | beta-lactamase | 0.0149 | 0.1407 | 0.2421 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0528 | 0.2905 |
Echinococcus granulosus | snurportin 1 | 0.0355 | 0.3617 | 0.6598 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0277 | 0.278 | 0.4875 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0035 | 0.0247 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.007 | 0.0563 | 0.4001 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0078 | 0.0646 | 0.356 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0035 | 0.0189 | 0.21 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0201 | 0.0353 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0107 | 0.0758 |
Trichomonas vaginalis | chaperonin, putative | 0.0024 | 0.0066 | 0.0116 |
Onchocerca volvulus | Huntingtin homolog | 0.0128 | 0.1186 | 0.8429 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0149 | 0.1407 | 0.1377 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0027 | 0.0101 | 0.0178 |
Brugia malayi | RNA binding protein | 0.0277 | 0.278 | 0.4875 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0187 | 0.1816 | 0.3143 |
Echinococcus granulosus | lamin | 0.0027 | 0.01 | 0.0183 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0107 | 0.1187 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1407 | 0.2467 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0035 | 0.0189 | 0.1039 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0053 | 0.0374 | 0.2662 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0528 | 0.375 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.007 | 0.0563 | 0.0987 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0201 | 0.0353 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0528 | 0.3592 |
Schistosoma mansoni | lamin | 0.0027 | 0.01 | 0.0176 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.0035 | 0.0061 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0078 | 0.0646 | 0.1179 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.1026 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0201 | 0.0353 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0092 | 0.0798 | 0.1456 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0201 | 0.0367 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0149 | 0.1407 | 0.2467 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0201 | 0.1214 |
Loa Loa (eye worm) | beta-lactamase | 0.0149 | 0.1407 | 0.2467 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0035 | 0.0189 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.1186 | 0.208 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0075 | 0.053 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.007 | 0.0563 | 0.0987 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.007 | 0.0559 | 0.0526 |
Brugia malayi | beta-lactamase family protein | 0.0149 | 0.1407 | 0.2467 |
Mycobacterium leprae | Probable lipase LipE | 0.0149 | 0.1407 | 0.4223 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0798 | 0.1399 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0257 | 0.2567 | 0.2541 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0189 | 0.1039 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0187 | 0.1816 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0101 | 0.0899 | 0.1576 |
Trichomonas vaginalis | glutaminase, putative | 0.055 | 0.5702 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0101 | 0.0899 | 0.1576 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0528 | 0.3592 |
Mycobacterium tuberculosis | Conserved protein | 0.0149 | 0.1407 | 0.1377 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0101 | 0.0899 | 0.1639 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0024 | 0.0066 | 0.0738 |
Schistosoma mansoni | tar DNA-binding protein | 0.0277 | 0.278 | 0.4875 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0107 | 0.0187 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0035 | 0.0189 | 0.1341 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0066 | 0.0116 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0201 | 0.1431 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0231 | 0.229 | 0.8623 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0149 | 0.1407 | 0.2467 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.01 | 0.0183 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0201 | 0.1962 |
Brugia malayi | Importin beta-1 subunit | 0.0033 | 0.0169 | 0.0296 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.0035 | 0.0063 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0528 | 0.3592 |
Entamoeba histolytica | Ran family GTPase | 0.0024 | 0.0075 | 0.0727 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0066 | 0.0471 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0149 | 0.1407 | 0.2467 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0149 | 0.1407 | 0.2467 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0149 | 0.1407 | 0.2467 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0528 | 0.3592 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0035 | 0.0189 | 0.21 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0189 | 0.1341 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0092 | 0.0798 | 0.1399 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0257 | 0.2567 | 0.2541 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0035 | 0.0189 | 0.1122 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0187 | 0.1816 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0035 | 0.0189 | 0.2517 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.007 | 0.0563 | 0.4001 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0095 | 0.0167 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0277 | 0.278 | 0.4875 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0101 | 0.0987 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0798 | 0.1399 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0075 | 0.029 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0201 | 0.0353 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1407 | 0.2467 |
Loa Loa (eye worm) | RNA binding protein | 0.0277 | 0.278 | 0.4875 |
Onchocerca volvulus | 0.0057 | 0.0424 | 0.3011 | |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0035 | 0.0189 | 0.1341 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0187 | 0.1816 | 0.3143 |
Schistosoma mansoni | ran | 0.0024 | 0.0075 | 0.0131 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0164 | 0.1565 | 0.2856 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0164 | 0.1565 | 0.2745 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0528 | 0.3592 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0149 | 0.1407 | 0.1377 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0101 | 0.0899 | 0.6387 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0101 | 0.0899 | 0.6387 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.1026 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.0035 | 0.0247 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0201 | 0.0353 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0035 | 0.0189 | 0.0331 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.01 | 0.0176 |
Echinococcus multilocularis | tumor protein p63 | 0.039 | 0.3989 | 0.7277 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0528 | 0.3592 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.