Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0318 | 0.4287 | 0.4093 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0427 | 0.0995 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0318 | 0.4287 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0069 | 0.0427 | 0.0247 |
Entamoeba histolytica | aldose reductase, putative | 0.0318 | 0.4287 | 1 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0092 | 0.0781 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0318 | 0.4287 | 0.4093 |
Loa Loa (eye worm) | oxidoreductase | 0.0318 | 0.4287 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0318 | 0.4287 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0318 | 0.4287 | 0.4093 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0318 | 0.4287 | 1 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0092 | 0.0781 | 0.1822 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0427 | 0.0995 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0092 | 0.0781 | 0.1142 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0427 | 0.0101 |
Schistosoma mansoni | aldo-keto reductase | 0.0318 | 0.4287 | 0.4093 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0318 | 0.4287 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0318 | 0.4287 | 0.4093 |
Loa Loa (eye worm) | oxidoreductase | 0.0318 | 0.4287 | 1 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0092 | 0.0781 | 0.5 |
Echinococcus multilocularis | aldehyde reductase | 0.0226 | 0.2858 | 0.2614 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0318 | 0.4287 | 0.4093 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0318 | 0.4287 | 0.4093 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0092 | 0.0781 | 0.0468 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0318 | 0.4287 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0427 | 0.0101 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0318 | 0.4287 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0318 | 0.4287 | 1 |
Onchocerca volvulus | 0.0318 | 0.4287 | 1 | |
Echinococcus multilocularis | aldo keto reductase | 0.0318 | 0.4287 | 0.4093 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0318 | 0.4287 | 0.4093 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0686 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0318 | 0.4287 | 0.4093 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0318 | 0.4287 | 0.4093 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0318 | 0.4287 | 0.4093 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0318 | 0.4287 | 1 |
Plasmodium vivax | aldehyde reductase, putative | 0.0092 | 0.0781 | 0.5 |
Onchocerca volvulus | 0.0092 | 0.0781 | 0.1822 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0092 | 0.0781 | 0.1822 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0092 | 0.0781 | 0.1822 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0069 | 0.0427 | 0.0247 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0427 | 0.0101 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0427 | 0.0101 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0092 | 0.0781 | 0.0468 |
Entamoeba histolytica | aldose reductase, putative | 0.0318 | 0.4287 | 1 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0092 | 0.0781 | 0.5 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0427 | 0.0101 |
Onchocerca volvulus | 0.0318 | 0.4287 | 1 | |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0318 | 0.4287 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0318 | 0.4287 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0318 | 0.4287 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0318 | 0.4287 | 0.4093 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0318 | 0.4287 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0318 | 0.4287 | 0.4093 |
Toxoplasma gondii | aldose reductase, putative | 0.0318 | 0.4287 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0427 | 0.0101 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0092 | 0.0781 | 0.1822 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0686 | 1 | 1 |
Schistosoma mansoni | pol-related | 0.0318 | 0.4287 | 0.4093 |
Echinococcus multilocularis | aldo keto reductase | 0.0318 | 0.4287 | 0.4093 |
Loa Loa (eye worm) | oxidoreductase | 0.0318 | 0.4287 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0318 | 0.4287 | 1 |
Giardia lamblia | Aldose reductase | 0.0318 | 0.4287 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0318 | 0.4287 | 0.4093 |
Trypanosoma cruzi | aldo-keto reductase | 0.0318 | 0.4287 | 1 |
Schistosoma mansoni | potassium channel beta | 0.0092 | 0.0781 | 0.0468 |
Onchocerca volvulus | 0.0318 | 0.4287 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0318 | 0.4287 | 0.4093 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0318 | 0.4287 | 0.4093 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0318 | 0.4287 | 0.4093 |
Echinococcus granulosus | aldehyde reductase | 0.0226 | 0.2858 | 0.2614 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0318 | 0.4287 | 0.4093 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0226 | 0.2858 | 0.5922 |
Loa Loa (eye worm) | oxidoreductase | 0.0318 | 0.4287 | 1 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0092 | 0.0781 | 0.1142 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0318 | 0.4287 | 0.4093 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 0.4287 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0318 | 0.4287 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0092 | 0.0781 | 0.1822 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0318 | 0.4287 | 0.4093 |
Echinococcus multilocularis | aldo keto reductase | 0.0318 | 0.4287 | 0.4093 |
Echinococcus granulosus | aldo keto reductase | 0.0318 | 0.4287 | 0.4093 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0318 | 0.4287 | 1 |
Onchocerca volvulus | 0.0318 | 0.4287 | 1 | |
Trypanosoma brucei | prostaglandin f synthase | 0.0318 | 0.4287 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0318 | 0.4287 | 0.4093 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0318 | 0.4287 | 0.4093 |
Echinococcus granulosus | hypothetical protein | 0.0318 | 0.4287 | 0.4093 |
Loa Loa (eye worm) | oxidoreductase | 0.0318 | 0.4287 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0318 | 0.4287 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0318 | 0.4287 | 1 |
Brugia malayi | NADH-dependent xylose reductase | 0.0092 | 0.0781 | 0.1142 |
Leishmania major | aldo-keto reductase-like protein | 0.0318 | 0.4287 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Onchocerca volvulus | 0.0318 | 0.4287 | 1 | |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0318 | 0.4287 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0318 | 0.4287 | 0.4093 |
Echinococcus multilocularis | aldo keto reductase | 0.0318 | 0.4287 | 0.4093 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0092 | 0.0781 | 0.0468 |
Giardia lamblia | Aldose reductase | 0.0318 | 0.4287 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0318 | 0.4287 | 0.4093 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0318 | 0.4287 | 1 |
Onchocerca volvulus | 0.0318 | 0.4287 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.