Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0053 | 0.0055 | 0.0055 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.0176 | 0.0176 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0215 | 0.0485 | 0.0485 |
Echinococcus multilocularis | prenyl (decaprenyl) diphosphate synthase | 0.1179 | 0.3053 | 0.3053 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.002 | 0.002 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.139 | 0.3613 | 0.3578 |
Plasmodium vivax | geranylgeranyl pyrophosphate synthase | 0.3789 | 1 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0013 | 0.0013 |
Onchocerca volvulus | 0.0452 | 0.1117 | 0.9495 | |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0087 | 0.0145 | 0.0145 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.3789 | 1 | 1 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase | 0.3789 | 1 | 1 |
Schistosoma mansoni | Replicative DNA helicase | 0.042 | 0.1031 | 0.1031 |
Plasmodium falciparum | octaprenyl pyrophosphate synthase | 0.1648 | 0.4301 | 0.427 |
Echinococcus multilocularis | farnesyl pyrophosphate synthase | 0.3789 | 1 | 1 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0064 | 0.0083 | 0.0029 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0085 | 0.0085 |
Echinococcus granulosus | farnesyl pyrophosphate synthase | 0.3789 | 1 | 1 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0197 | 0.0438 | 0.0438 |
Schistosoma mansoni | glutaminase | 0.0546 | 0.1367 | 0.1367 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase, putative | 0.3789 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0154 | 0.0154 |
Schistosoma mansoni | geranylgeranyl pyrophosphate synthase | 0.139 | 0.3613 | 0.3613 |
Echinococcus granulosus | caspase 2 | 0.0053 | 0.0055 | 0.0055 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0604 | 0.152 | 0.1473 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.0085 | 0.0085 |
Trypanosoma brucei | unspecified product | 0.006 | 0.0073 | 0.0019 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0079 | 0.0079 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0087 | 0.0145 | 0.0145 |
Schistosoma mansoni | hypothetical protein | 0.1202 | 0.3112 | 0.3112 |
Loa Loa (eye worm) | hypothetical protein | 0.0452 | 0.1117 | 0.1117 |
Trichomonas vaginalis | glutaminase, putative | 0.0546 | 0.1367 | 0.132 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.1648 | 0.4301 | 0.4301 |
Leishmania major | carbonic anhydrase-like protein | 0.0215 | 0.0485 | 0.0432 |
Plasmodium falciparum | carbonic anhydrase | 0.0116 | 0.0223 | 0.0169 |
Loa Loa (eye worm) | runx1 | 0.0057 | 0.0064 | 0.0064 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.0085 | 0.0085 |
Onchocerca volvulus | 0.006 | 0.0072 | 0.0157 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0085 | 0.0139 | 0.0085 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0103 | 0.0189 | 0.0135 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0116 | 0.0223 | 0.0223 |
Leishmania major | farnesyl pyrophosphate synthase | 0.3789 | 1 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0472 | 0.1169 | 0.1169 |
Leishmania major | polyprenyl synthase, putative | 0.139 | 0.3613 | 0.3578 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0307 | 0.0307 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0116 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0127 | 0.0127 |
Trichomonas vaginalis | geranylgeranyl diphosphate synthase, putative | 0.3789 | 1 | 1 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.3789 | 1 | 1 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0053 | 0.0055 | 0.0055 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0053 | 0.0055 | 0.0034 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0138 | 0.0281 | 0.0228 |
Onchocerca volvulus | 0.0197 | 0.0438 | 0.3426 | |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthase, putative | 0.1648 | 0.4301 | 1 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0224 | 0.051 | 0.051 |
Onchocerca volvulus | 0.0473 | 0.1173 | 1 | |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.009 | 0.0154 | 0.0154 |
Giardia lamblia | Farnesyl diphosphate synthase | 0.3789 | 1 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0138 | 0.0281 | 0.0228 |
Trypanosoma brucei | phosphoglycerate kinase | 0.0064 | 0.0083 | 0.0029 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0077 | 0.012 | 0.012 |
Toxoplasma gondii | phosphoglycerate kinase PGKI | 0.0174 | 0.0376 | 0.0356 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0286 | 0.0674 | 0.0623 |
Echinococcus multilocularis | muscleblind protein | 0.0472 | 0.1169 | 0.1169 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0078 | 0.0121 | 0.0067 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0472 | 0.1169 | 0.1169 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.012 | 0.012 |
Wolbachia endosymbiont of Brugia malayi | replicative DNA helicase | 0.042 | 0.1031 | 0.167 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.0093 | 0.0038 |
Leishmania major | solanesyl-diphosphate synthase, putative | 0.1648 | 0.4301 | 0.427 |
Echinococcus multilocularis | geranylgeranyl pyrophosphate synthase | 0.139 | 0.3613 | 0.3613 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0039 | 0.0017 | 0.0017 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0053 | 0.0055 | 0.0055 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0085 | 0.0139 | 0.0085 |
Onchocerca volvulus | 0.009 | 0.0154 | 0.0888 | |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0224 | 0.051 | 0.051 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0078 | 0.0121 | 0.0101 |
Plasmodium vivax | phosphoglycerate kinase, putative | 0.0174 | 0.0376 | 0.0323 |
Mycobacterium tuberculosis | Probable polyprenyl-diphosphate synthase GrcC1 (polyprenyl pyrophosphate synthetase) | 0.0469 | 0.1161 | 0.1031 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0116 | 0.0223 | 0.0223 |
Trypanosoma cruzi | solanesyl-diphosphate synthase | 0.1648 | 0.4301 | 0.427 |
Trichomonas vaginalis | phosphoglycerate kinase, putative | 0.0174 | 0.0376 | 0.0323 |
Trypanosoma brucei | solanesyl-diphosphate synthase, putative | 0.1648 | 0.4301 | 0.427 |
Echinococcus granulosus | dna polymerase kappa | 0.014 | 0.0287 | 0.0287 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.0176 | 0.0176 |
Loa Loa (eye worm) | glutaminase | 0.0546 | 0.1367 | 0.1367 |
Mycobacterium tuberculosis | Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) | 0.3789 | 1 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0138 | 0.0281 | 0.0281 |
Loa Loa (eye worm) | geranylgeranyl pyrophosphate synthetase | 0.139 | 0.3613 | 0.3613 |
Schistosoma mansoni | hypothetical protein | 0.0116 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0197 | 0.0438 | 0.0438 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0055 | 0.0055 |
Echinococcus multilocularis | dna polymerase eta | 0.0138 | 0.0281 | 0.0281 |
Loa Loa (eye worm) | MBCTL1 | 0.0224 | 0.051 | 0.051 |
Mycobacterium leprae | Conserved hypothetical protein | 0.055 | 0.1378 | 0.2554 |
Brugia malayi | hypothetical protein | 0.0452 | 0.1117 | 0.1117 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0085 | 0.0085 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.139 | 0.3613 | 0.3578 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.0101 | 0.0101 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0286 | 0.0674 | 0.0623 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.006 | 0.0072 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1169 | 0.1169 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1169 | 0.1169 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0057 | 0.0066 | 0.0066 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Mycobacterium ulcerans | phosphoglycerate kinase | 0.0174 | 0.0376 | 0.0092 |
Echinococcus granulosus | phosphoglycerate kinase 1 | 0.0174 | 0.0376 | 0.0376 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.006 | 0.0072 | 0.0072 |
Leishmania major | DNA polymerase eta, putative | 0.0078 | 0.0121 | 0.0067 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0215 | 0.0485 | 0.0485 |
Echinococcus granulosus | decaprenyl diphosphate synthase subunit 1 | 0.1648 | 0.4301 | 0.4301 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0053 | 0.0055 | 0.0034 |
Echinococcus multilocularis | caspase 8 | 0.0053 | 0.0055 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0055 | 0.0055 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0197 | 0.0438 | 0.0438 |
Echinococcus granulosus | caspase | 0.0053 | 0.0055 | 0.0055 |
Mycobacterium tuberculosis | Probable phosphoglycerate kinase Pgk | 0.0174 | 0.0376 | 0.0234 |
Mycobacterium ulcerans | polyprenyl diphosphate synthetase, GrcC1 | 0.1648 | 0.4301 | 0.4133 |
Echinococcus multilocularis | carbonic anhydrase | 0.0116 | 0.0223 | 0.0223 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.006 | 0.0072 | 0.0052 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0085 | 0.0085 |
Trypanosoma brucei | unspecified product | 0.006 | 0.0073 | 0.0019 |
Echinococcus multilocularis | dna polymerase kappa | 0.014 | 0.0287 | 0.0287 |
Echinococcus granulosus | prenyl decaprenyl diphosphate synthase | 0.1179 | 0.3053 | 0.3053 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0067 | 0.0093 | 0.0093 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0197 | 0.0438 | 0.3426 |
Schistosoma mansoni | farnesyl pyrophosphate synthase | 0.3789 | 1 | 1 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.1648 | 0.4301 | 0.427 |
Echinococcus multilocularis | carbonic anhydrase | 0.0116 | 0.0223 | 0.0223 |
Brugia malayi | Phosphoglycerate kinase | 0.0174 | 0.0376 | 0.0376 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.006 | 0.0072 | 0.0072 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.0085 | 0.0085 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0116 | 0.0223 | 0.0223 |
Schistosoma mansoni | bromodomain containing protein | 0.0066 | 0.0089 | 0.0089 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.0085 | 0.0085 |
Brugia malayi | geranylgeranyl pyrophosphate synthetase | 0.139 | 0.3613 | 0.3613 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.0176 | 0.0176 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0087 | 0.0145 | 0.0145 |
Leishmania major | phosphoglycerate kinase B, cytosolic | 0.0174 | 0.0376 | 0.0323 |
Chlamydia trachomatis | replicative DNA helicase | 0.042 | 0.1031 | 0.2449 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0085 | 0.0139 | 0.0085 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0053 | 0.0055 | 0.0055 |
Schistosoma mansoni | phosphoglycerate kinase | 0.0174 | 0.0376 | 0.0376 |
Brugia malayi | RNA binding protein | 0.0065 | 0.0085 | 0.0085 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.051 | 0.051 |
Plasmodium falciparum | phosphoglycerate kinase | 0.0174 | 0.0376 | 0.0323 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0013 | 0.0013 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0073 | 0.0108 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0452 | 0.1117 | 0.1117 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0073 | 0.0108 | 0.0054 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.3789 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.008 | 0.0127 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.002 | 0.002 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.3789 | 1 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.0093 | 0.0038 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.0085 | 0.0085 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0067 | 0.0093 | 0.0093 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0416 | 0.102 | 0.102 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0215 | 0.0485 | 0.0485 |
Treponema pallidum | replicative DNA helicase (dnaB) | 0.042 | 0.1031 | 0.2025 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0318 | 0.076 | 0.0623 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0064 | 0.0083 | 0.0029 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0224 | 0.051 | 0.051 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0174 | 0.0376 | 0.0323 |
Echinococcus multilocularis | caspase 2 | 0.0053 | 0.0055 | 0.0055 |
Entamoeba histolytica | bifunctional short chain isoprenyl diphosphate synthase, putative | 0.1179 | 0.3053 | 0.7034 |
Onchocerca volvulus | 0.0148 | 0.0307 | 0.2253 | |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.0085 | 0.0085 |
Mycobacterium tuberculosis | RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. | 0.145 | 0.3774 | 0.3682 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0067 | 0.0093 | 0.0093 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.1179 | 0.3053 | 0.682 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0077 | 0.012 | 0.012 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0067 | 0.0093 | 0.0093 |
Mycobacterium leprae | PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) | 0.1648 | 0.4301 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.078 | 0.199 | 0.199 |
Toxoplasma gondii | phosphoglycerate kinase PGKII | 0.0174 | 0.0376 | 0.0356 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0197 | 0.0438 | 0.0438 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0215 | 0.0485 | 0.0485 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0099 | 0.0176 | 0.0176 |
Trypanosoma brucei | phosphoglycerate kinase | 0.0174 | 0.0376 | 0.0323 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0087 | 0.0145 | 0.0145 |
Brugia malayi | Polyprenyl synthetase family protein | 0.1648 | 0.4301 | 0.4301 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.009 | 0.0154 | 0.0154 |
Echinococcus multilocularis | phosphoglycerate kinase 1 | 0.0174 | 0.0376 | 0.0376 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Brugia malayi | glutaminase DH11.1 | 0.0546 | 0.1367 | 0.1367 |
Leishmania major | DNA polymerase eta, putative | 0.0138 | 0.0281 | 0.0228 |
Schistosoma mansoni | glutathione synthetase | 0.1179 | 0.3053 | 0.3053 |
Brugia malayi | Muscleblind-like protein | 0.0472 | 0.1169 | 0.1169 |
Mycobacterium tuberculosis | Probable replicative DNA helicase DnaB | 0.187 | 0.4892 | 0.4817 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.014 | 0.0287 | 0.0234 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.014 | 0.0287 | 0.0234 |
Loa Loa (eye worm) | twinkle helicase | 0.012 | 0.0233 | 0.0233 |
Mycobacterium ulcerans | polyprenyl synthetase IdsB | 0.1179 | 0.3053 | 0.2848 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0077 | 0.012 | 0.012 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.0176 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0376 | 0.0376 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.0176 | 0.0176 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0197 | 0.0438 | 0.0438 |
Schistosoma mansoni | phosphoglycerate kinase | 0.0174 | 0.0376 | 0.0376 |
Brugia malayi | Pre-SET motif family protein | 0.0416 | 0.102 | 0.102 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.0176 | 0.0176 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.3789 | 1 | 1 |
Trypanosoma brucei | farnesyl pyrophosphate synthase | 0.3789 | 1 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0197 | 0.0438 | 0.0438 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0224 | 0.051 | 0.051 |
Echinococcus granulosus | carbonic anhydrase | 0.0116 | 0.0223 | 0.0223 |
Echinococcus granulosus | geminin | 0.0365 | 0.0886 | 0.0886 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0073 | 0.0108 | 0.0054 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.0093 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0187 | 0.0187 |
Brugia malayi | polk-prov protein | 0.008 | 0.0127 | 0.0127 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0604 | 0.152 | 0.1473 |
Echinococcus multilocularis | Protein lozenge | 0.0057 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0101 | 0.0101 |
Loa Loa (eye worm) | glutaminase 2 | 0.0546 | 0.1367 | 0.1367 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.009 | 0.0154 | 0.0154 |
Trypanosoma brucei | phosphoglycerate kinase, putative | 0.0064 | 0.0083 | 0.0029 |
Brugia malayi | hypothetical protein | 0.0148 | 0.0307 | 0.0307 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0215 | 0.0485 | 0.0485 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0067 | 0.0093 | 0.0093 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0215 | 0.0485 | 0.0485 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0116 | 0.0223 | 0.0223 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.008 | 0.0127 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.011 | 0.011 |
Trichomonas vaginalis | phosphoglycerate kinase, putative | 0.0174 | 0.0376 | 0.0323 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0174 | 0.0376 | 0.0323 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0604 | 0.152 | 0.1473 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0215 | 0.0485 | 0.0432 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0032 | 0.0032 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.1648 | 0.4301 | 0.427 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.0101 | 0.0101 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0116 | 0.0223 | 0.0223 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0138 | 0.0281 | 0.0281 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.0187 | 0.0187 |
Brugia malayi | Phosphoglycerate kinase | 0.0064 | 0.0083 | 0.0083 |
Echinococcus granulosus | carbonic anhydrase | 0.0116 | 0.0223 | 0.0223 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0053 | 0.0055 | 0.0055 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0053 | 0.0055 | 0.0055 |
Toxoplasma gondii | hypothetical protein | 0.0116 | 0.0223 | 0.0203 |
Schistosoma mansoni | hypothetical protein | 0.0365 | 0.0886 | 0.0886 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.078 | 0.199 | 0.199 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0224 | 0.051 | 0.051 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.0176 | 0.0176 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0116 | 0.0223 | 0.0223 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0067 | 0.0093 | 0.0038 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0053 | 0.0055 | 0.0055 |
Schistosoma mansoni | lozenge | 0.0057 | 0.0064 | 0.0064 |
Echinococcus granulosus | dna polymerase eta | 0.0138 | 0.0281 | 0.0281 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0064 | 0.0083 | 0.0029 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0286 | 0.0674 | 0.0623 |
Treponema pallidum | octaprenyl-diphosphate synthase | 0.139 | 0.3613 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0077 | 0.012 | 0.012 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.0085 | 0.0085 |
Echinococcus multilocularis | decaprenyl diphosphate synthase subunit 1 | 0.1648 | 0.4301 | 0.4301 |
Echinococcus multilocularis | caspase | 0.0053 | 0.0055 | 0.0055 |
Brugia malayi | mbt repeat family protein | 0.0197 | 0.0438 | 0.0438 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.01 | 0.018 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0027 | 0.0027 |
Echinococcus granulosus | carbonic anhydrase II | 0.0215 | 0.0485 | 0.0485 |
Brugia malayi | mbt repeat family protein | 0.0197 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0223 | 0.0223 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0197 | 0.0438 | 0.0438 |
Mycobacterium leprae | PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase | 0.042 | 0.1031 | 0.167 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0881 | 0.2259 | 0.2259 |
Echinococcus granulosus | carbonic anhydrase | 0.0116 | 0.0223 | 0.0223 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.3789 | 1 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0116 | 0.0223 | 0.0223 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0087 | 0.0145 | 0.0145 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0085 | 0.0085 |
Toxoplasma gondii | hypothetical protein | 0.0097 | 0.0172 | 0.0152 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthetase, putative | 0.1648 | 0.4301 | 1 |
Echinococcus multilocularis | geminin | 0.0365 | 0.0886 | 0.0886 |
Echinococcus multilocularis | carbonic anhydrase | 0.0116 | 0.0223 | 0.0223 |
Chlamydia trachomatis | geranylgeranyl pyrophosphate synthase | 0.1179 | 0.3053 | 1 |
Brugia malayi | Cell death protein 3 precursor | 0.0053 | 0.0055 | 0.0055 |
Mycobacterium tuberculosis | Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) | 0.1179 | 0.3053 | 0.295 |
Entamoeba histolytica | phosphoglycerate kinase, putative | 0.0174 | 0.0376 | 0.0673 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0079 | 0.0079 |
Brugia malayi | Pre-SET motif family protein | 0.006 | 0.0072 | 0.0072 |
Plasmodium vivax | octaprenyl pyrophosphate synthase, putative | 0.1648 | 0.4301 | 0.427 |
Leishmania major | DNA polymerase kappa, putative | 0.01 | 0.018 | 0.0127 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0039 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0099 | 0.0176 | 0.0176 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.1648 | 0.4301 | 0.4289 |
Leishmania major | phosphoglycerate kinase C, glycosomal | 0.0174 | 0.0376 | 0.0323 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.009 | 0.0154 | 0.0154 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.014 | 0.0287 | 0.0234 |
Brugia malayi | Bromodomain containing protein | 0.0078 | 0.0122 | 0.0122 |
Mycobacterium tuberculosis | Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) | 0.1179 | 0.3053 | 0.295 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.01 | 0.018 | 0.0127 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0215 | 0.0485 | 0.0432 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0116 | 0.0223 | 0.0223 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.0281 | 0.0281 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0085 | 0.0085 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0127 | 0.0252 | 0.0198 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0064 | 0.0083 | 0.0029 |
Mycobacterium tuberculosis | Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate | 0.1179 | 0.3053 | 0.295 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0085 | 0.0139 | 0.0085 |
Schistosoma mansoni | carbonic anhydrase | 0.0116 | 0.0223 | 0.0223 |
Plasmodium vivax | SET domain protein, putative | 0.006 | 0.0072 | 0.0018 |
Mycobacterium ulcerans | hypothetical protein | 0.0318 | 0.076 | 0.0487 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0053 | 0.0055 | 0.0034 |
Trypanosoma cruzi | 3-phosphoglycerate kinase, glycosomal | 0.0064 | 0.0083 | 0.0029 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.0187 | 0.0187 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0064 | 0.0083 | 0.0029 |
Schistosoma mansoni | trans-prenyltransferase | 0.1648 | 0.4301 | 0.4301 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0215 | 0.0485 | 0.0485 |
Mycobacterium ulcerans | replicative DNA helicase DnaB | 0.042 | 0.1031 | 0.0766 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0438 | 0.0438 |
Echinococcus granulosus | geranylgeranyl pyrophosphate synthase | 0.139 | 0.3613 | 0.3613 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0087 | 0.0145 | 0.0125 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.1648 | 0.4301 | 1 |
Giardia lamblia | Phosphoglycerate kinase | 0.0174 | 0.0376 | 0.0199 |
Trichomonas vaginalis | set domain proteins, putative | 0.0473 | 0.1173 | 0.1125 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0197 | 0.0438 | 0.0438 |
Trypanosoma brucei | unspecified product | 0.0127 | 0.0252 | 0.0198 |
Plasmodium falciparum | geranylgeranyl pyrophosphate synthase, putative | 0.3789 | 1 | 1 |
Mycobacterium ulcerans | glutaminase | 0.0546 | 0.1367 | 0.1112 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.014 | 0.0287 | 0.0234 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0604 | 0.152 | 0.1473 |
Echinococcus granulosus | caspase 8 | 0.0053 | 0.0055 | 0.0055 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0087 | 0.0145 | 0.0145 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0215 | 0.0485 | 0.0432 |
Schistosoma mansoni | hypothetical protein | 0.0365 | 0.0886 | 0.0886 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.01 | 0.018 | 0.0036 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.014 | 0.0287 | 0.0234 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0224 | 0.051 | 0.051 |
Trypanosoma brucei | phosphoglycerate kinase | 0.0174 | 0.0376 | 0.0323 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.0187 | 0.0187 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.