Detailed information for compound 54038

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 316.236 | Formula: C17H18BrN
  • H donors: 1 H acceptors: 0 LogP: 4.22 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN[C@H]1CC[C@H](c2c1cccc2)c1ccc(cc1)Br
  • InChi: 1S/C17H18BrN/c1-19-17-11-10-14(12-6-8-13(18)9-7-12)15-4-2-3-5-16(15)17/h2-9,14,17,19H,10-11H2,1H3/t14-,17-/m0/s1
  • InChiKey: RHZPRTGVQUYQFA-YOEHRIQHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum acyl-CoA synthetase 0.0043 0.0115 0.0577
Echinococcus multilocularis pyruvate kinase 0.0025 0.0036 0.0025
Schistosoma mansoni amine GPCR 0.0085 0.0312 0.029
Plasmodium vivax amine transporter, putative 0.0369 0.1629 1
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0361 0.1594 0.1575
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0025 0.0036 0.0054
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Loa Loa (eye worm) animal heme peroxidase 0.0672 0.3038 0.3038
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0369 0.1629 1
Onchocerca volvulus 0.0085 0.0312 0.0285
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0369 0.1629 0.162
Loa Loa (eye worm) hypothetical protein 0.0369 0.1629 0.1629
Entamoeba histolytica acyl-CoA synthetase, putative 0.0057 0.0182 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0085 0.0312 0.029
Brugia malayi hypothetical protein 0.0369 0.1629 0.161
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0112 0.0559
Onchocerca volvulus 0.0085 0.0312 0.0285
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0085 0.0312 0.0301
Schistosoma mansoni neuropeptide receptor 0.0085 0.0312 0.029
Schistosoma mansoni hypothetical protein 0.0085 0.0312 0.029
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0043 0.0115 0.0498
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0061 0.0202 0.1115
Echinococcus granulosus neuropeptide s receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0595 0.2681 0.2681
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0022 0.5
Echinococcus multilocularis serotonin transporter 0.2171 1 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0186 0.0164
Onchocerca volvulus 0.0085 0.0312 0.0285
Schistosoma mansoni rab6-interacting 0.0024 0.0028 0.0005
Onchocerca volvulus 0.0369 0.1629 0.1606
Brugia malayi Animal haem peroxidase family protein 0.0672 0.3038 0.3022
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0057 0.0182 0.06
Schistosoma mansoni biogenic amine receptor 0.0085 0.0312 0.029
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0554 0.2488 1
Brugia malayi Pyruvate kinase, M2 isozyme 0.0025 0.0036 0.0013
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0061 0.0202 0.0202
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0085 0.0312 0.029
Brugia malayi hypothetical protein 0.0085 0.0312 0.029
Echinococcus granulosus mitogen activated protein kinase 0.0061 0.0202 0.018
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0028 0.0005
Loa Loa (eye worm) TYRA-2 protein 0.0085 0.0312 0.0312
Onchocerca volvulus 0.0059 0.0193 0.0166
Echinococcus granulosus biogenic amine 5HT receptor 0.0595 0.2681 0.2664
Schistosoma mansoni histamine h1 receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0369 0.1629 0.161
Echinococcus granulosus neuropeptides capa receptor 0.0085 0.0312 0.029
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1153 0.5269 0.5264
Echinococcus granulosus orexin receptor type 2 0.0085 0.0312 0.029
Onchocerca volvulus 0.0057 0.0182 0.0155
Loa Loa (eye worm) hypothetical protein 0.0057 0.0182 0.0182
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0028 0.0017
Trypanosoma brucei protein kinase, putative 0.0061 0.0202 0.1141
Schistosoma mansoni loxhd1 0.0024 0.0028 0.0005
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0042 0.0112 0.0112
Echinococcus multilocularis 0.0042 0.0112 0.0102
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0369 0.1629 0.161
Onchocerca volvulus 0.0085 0.0312 0.0285
Schistosoma mansoni sodium/chloride dependent transporter 0.2171 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0202 1
Brugia malayi G protein-coupled receptor 0.0085 0.0312 0.029
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0369 0.1629 0.162
Brugia malayi Animal haem peroxidase family protein 0.0672 0.3038 0.3022
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0085 0.0312 0.029
Echinococcus granulosus sex peptide receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Brugia malayi RE15519p 0.0085 0.0312 0.029
Brugia malayi Animal haem peroxidase family protein 0.0672 0.3038 0.3022
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0085 0.0312 0.0301
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Leishmania major pyruvate kinase 0.0025 0.0036 0.0085
Brugia malayi amine oxidase, flavin-containing family protein 0.0042 0.0112 0.009
Brugia malayi ORL1-like opioid receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.0369 0.1629 0.1629
Echinococcus multilocularis neuropeptide FF receptor 2 0.0085 0.0312 0.0301
Echinococcus granulosus pyruvate kinase 0.0025 0.0036 0.0013
Brugia malayi hypothetical protein 0.0024 0.0028 0.0005
Schistosoma mansoni peroxidasin 0.0672 0.3038 0.3022
Echinococcus multilocularis neuropeptide receptor 0.0085 0.0312 0.0301
Schistosoma mansoni amine oxidase 0.0042 0.0112 0.009
Echinococcus multilocularis dro:myosuppressin receptor 0.0085 0.0312 0.0301
Schistosoma mansoni hypothetical protein 0.0085 0.0312 0.029
Brugia malayi Pyruvate kinase, muscle isozyme 0.0025 0.0036 0.0013
Loa Loa (eye worm) hypothetical protein 0.0369 0.1629 0.1629
Loa Loa (eye worm) pyruvate kinase 0.0025 0.0036 0.0036
Echinococcus granulosus tumor protein p63 0.0406 0.1801 0.1783
Brugia malayi hypothetical protein 0.0085 0.0312 0.029
Echinococcus granulosus g protein coupled receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0042 0.0112 0.0112
Schistosoma mansoni neuropeptide receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Echinococcus granulosus tm gpcr rhodopsin 0.1153 0.5269 0.5258
Schistosoma mansoni peroxidasin 0.0672 0.3038 0.3022
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0061 0.0202 0.1141
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0595 0.2682 1
Echinococcus multilocularis neuropeptide receptor 0.0085 0.0312 0.0301
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0085 0.0312 0.0312
Mycobacterium ulcerans hypothetical protein 0.0057 0.0182 0.06
Plasmodium falciparum amino acid transporter, putative 0.0369 0.1629 1
Echinococcus multilocularis pyruvate kinase 0.0025 0.0036 0.0025
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0057 0.0182 0.06
Echinococcus granulosus rhodopsin orphan GPCR 0.0085 0.0312 0.029
Onchocerca volvulus Neuropeptide F receptor homolog 0.0085 0.0312 0.0285
Loa Loa (eye worm) hypothetical protein 0.2171 1 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0974 0.4438 0.4432
Schistosoma mansoni polycystin 1-related 0.0024 0.0028 0.0005
Echinococcus granulosus neuropeptide receptor A26 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0043 0.0115 0.0115
Schistosoma mansoni hypothetical protein 0.0085 0.0312 0.029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0085 0.0312 0.0301
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0028 0.0028
Echinococcus granulosus neuropeptide Y receptor 0.0085 0.0312 0.029
Schistosoma mansoni amine GPCR 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Brugia malayi MAP kinase sur-1 0.0061 0.0202 0.018
Echinococcus multilocularis somatostatin receptor 0.0085 0.0312 0.0301
Schistosoma mansoni sodium-dependent amino acid transporter 0.0369 0.1629 0.161
Brugia malayi G protein-coupled receptor F59B2.13 0.0085 0.0312 0.029
Echinococcus granulosus rhodopsin orphan GPCR 0.0085 0.0312 0.029
Brugia malayi AMP-binding enzyme family protein 0.0057 0.0182 0.016
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Schistosoma mansoni pyruvate kinase 0.0025 0.0036 0.0013
Plasmodium falciparum pyruvate kinase 0.0025 0.0036 0.0083
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0369 0.1629 0.161
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0085 0.0312 0.029
Onchocerca volvulus 0.0085 0.0312 0.0285
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0369 0.1629 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0369 0.1629 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0066 0.0225 0.0215
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0022 0.0022
Plasmodium vivax pyruvate kinase, putative 0.0025 0.0036 0.0083
Loa Loa (eye worm) hypothetical protein 0.0595 0.2681 0.2681
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0085 0.0312 0.029
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0085 0.0312 0.029
Brugia malayi larval opioid receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0059 0.0193 0.0193
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0369 0.1629 0.161
Echinococcus granulosus 7TM GPCR rhodopsin 0.0085 0.0312 0.029
Brugia malayi Serotonin receptor 0.0085 0.0312 0.029
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0085 0.0312 0.0301
Loa Loa (eye worm) hypothetical protein 0.0043 0.0115 0.0115
Toxoplasma gondii pyruvate kinase PyK1 0.0025 0.0036 0.0083
Echinococcus multilocularis serotonin receptor 0.0595 0.2681 0.2673
Brugia malayi Peroxidasin 0.0672 0.3038 0.3022
Echinococcus granulosus fmrfamide receptor 0.0085 0.0312 0.029
Schistosoma mansoni biogenic amine receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0369 0.1629 0.1629
Toxoplasma gondii hypothetical protein 0.0369 0.1629 1
Echinococcus multilocularis fmrfamide receptor 0.0085 0.0312 0.0301
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0369 0.1629 0.161
Brugia malayi neuropeptide F receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Onchocerca volvulus 0.0085 0.0312 0.0285
Brugia malayi AMP-binding enzyme family protein 0.0057 0.0182 0.016
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0182 0.06
Echinococcus granulosus alpha 1A adrenergic receptor 0.0085 0.0312 0.029
Brugia malayi Dopamine receptor 0.0085 0.0312 0.029
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0369 0.1629 0.161
Loa Loa (eye worm) hypothetical protein 0.0399 0.177 0.177
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0028 0.0032
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0022 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0085 0.0312 0.0301
Onchocerca volvulus 0.0085 0.0312 0.0285
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0202 1
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Echinococcus granulosus allatostatin A receptor 0.0085 0.0312 0.029
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0112 0.0559
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0085 0.0312 0.0285
Plasmodium falciparum transporter, putative 0.0369 0.1629 1
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Echinococcus multilocularis g protein coupled receptor 0.0085 0.0312 0.0301
Echinococcus multilocularis rhodopsin orphan GPCR 0.0085 0.0312 0.0301
Schistosoma mansoni amine GPCR 0.0255 0.11 0.108
Echinococcus multilocularis conserved hypothetical protein 0.1482 0.6798 0.6795
Toxoplasma gondii histone lysine-specific demethylase 0.0042 0.0112 0.0559
Schistosoma mansoni sodium/chloride dependent transporter 0.0369 0.1629 0.161
Echinococcus multilocularis protoporphyrinogen oxidase 0.0042 0.0112 0.0102
Echinococcus granulosus rhodopsin orphan GPCR 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0043 0.0115 0.0115
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0085 0.0312 0.029
Schistosoma mansoni hypothetical protein 0.0058 0.0186 0.0164
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0369 0.1629 0.1629
Onchocerca volvulus 0.0085 0.0312 0.0285
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0182 0.06
Loa Loa (eye worm) solute carrier family 6 member 4 0.2171 1 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0085 0.0312 0.029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0085 0.0312 0.029
Onchocerca volvulus Peroxidase homolog 0.0672 0.3038 0.3019
Onchocerca volvulus 0.0085 0.0312 0.0285
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0085 0.0312 0.0301
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Schistosoma mansoni opsin-like receptor 0.0085 0.0312 0.029
Echinococcus multilocularis g-protein coupled receptor 0.0085 0.0312 0.0301
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0085 0.0312 0.029
Echinococcus multilocularis neuropeptides capa receptor 0.0085 0.0312 0.0301
Brugia malayi hypothetical protein 0.0085 0.0312 0.029
Schistosoma mansoni cellular tumor antigen P53 0.0059 0.0193 0.0171
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0369 0.1629 0.161
Loa Loa (eye worm) serotonin transporter b 0.2171 1 1
Onchocerca volvulus 0.0085 0.0312 0.0285
Echinococcus multilocularis neuropeptide Y receptor 0.0085 0.0312 0.0301
Brugia malayi putative neuropeptide receptor NPR1 0.0085 0.0312 0.029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0085 0.0312 0.029
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0057 0.0182 0.06
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0042 0.0112 0.0559
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Echinococcus granulosus sodium and chloride dependent glycine 0.0369 0.1629 0.161
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0369 0.1629 0.161
Brugia malayi hypothetical protein 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.0043 0.0115 0.0115
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0369 0.1629 0.161
Echinococcus multilocularis tumor protein p63 0.0406 0.1801 0.1792
Giardia lamblia Kinase, CMGC MAPK 0.0061 0.0202 1
Echinococcus granulosus serotonin receptor 0.0085 0.0312 0.029
Echinococcus granulosus survival motor neuron protein 1 0.0284 0.1236 0.1216
Echinococcus multilocularis mitogen activated protein kinase 3 0.0061 0.0202 0.0191
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0085 0.0312 0.0301
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0042 0.0112 0.0559
Chlamydia trachomatis protoporphyrinogen oxidase 0.0042 0.0112 0.0481
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0085 0.0312 0.0301
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Loa Loa (eye worm) animal heme peroxidase 0.0672 0.3038 0.3038
Onchocerca volvulus 0.0042 0.0112 0.0085
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0369 0.1629 0.162
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0022 0.1234
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0061 0.0202 0.1141
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0028 0.0032
Echinococcus multilocularis sex peptide receptor 0.0085 0.0312 0.0301
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0085 0.0312 0.029
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.2171 1 1
Echinococcus granulosus G protein coupled receptor 139 0.0085 0.0312 0.029
Brugia malayi hypothetical protein 0.0085 0.0312 0.029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.004 0.0104 0.0332
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0085 0.0312 0.0301
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.004 0.0104 0.0332
Mycobacterium tuberculosis Possible oxidoreductase 0.0042 0.0112 0.0365
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0369 0.1629 0.161
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0061 0.0202 0.1141
Leishmania major 4-coumarate:coa ligase-like protein 0.0057 0.0182 0.1015
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0369 0.1629 0.161
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0595 0.2682 1
Plasmodium vivax hypothetical protein, conserved 0.0369 0.1629 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0361 0.1594 0.1594
Brugia malayi AMP-binding enzyme family protein 0.0057 0.0182 0.016
Schistosoma mansoni sodium/chloride dependent transporter 0.0369 0.1632 0.1613
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.0042 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.2171 1 1
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0112 0.0572
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0399 0.177 0.1752
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Plasmodium falciparum protoporphyrinogen oxidase 0.0042 0.0112 0.0559
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Trypanosoma cruzi pyruvate kinase 2, putative 0.0025 0.0036 0.0085
Echinococcus multilocularis peroxidasin 0.0672 0.3038 0.303
Onchocerca volvulus Peroxidasin homolog 0.0672 0.3038 0.3019
Echinococcus multilocularis g protein coupled receptor 0.0085 0.0312 0.0301
Loa Loa (eye worm) hypothetical protein 0.0399 0.177 0.177
Loa Loa (eye worm) norepinephrine transporter 0.2171 1 1
Echinococcus multilocularis neuropeptide s receptor 0.0085 0.0312 0.0301
Brugia malayi Serotonin receptor 0.1539 0.7062 0.7055
Loa Loa (eye worm) hypothetical protein 0.0057 0.0182 0.0182
Entamoeba histolytica acyl-CoA synthetase, putative 0.0057 0.0182 1
Brugia malayi Animal haem peroxidase family protein 0.0672 0.3038 0.3022
Brugia malayi hypothetical protein 0.0042 0.0112 0.009
Trypanosoma brucei pyruvate kinase 1, putative 0.0025 0.0036 0.0085
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0028 0.0017
Loa Loa (eye worm) hypothetical protein 0.0369 0.1629 0.1629
Schistosoma mansoni opsin-like receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0184 0.0774 0.0774
Echinococcus granulosus tm gpcr rhodopsin 0.0085 0.0312 0.029
Echinococcus granulosus dro:myosuppressin receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0057 0.0182 0.0182
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0085 0.0312 0.0301
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0042 0.0112 0.0559
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0085 0.0312 0.029
Trichomonas vaginalis pyruvate kinase, putative 0.0025 0.0036 0.0742
Brugia malayi Melatonin receptor type 1A 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Loa Loa (eye worm) melatonin receptor type 1A 0.0085 0.0312 0.0312
Echinococcus granulosus RUN 0.0024 0.0028 0.0005
Loa Loa (eye worm) hypothetical protein 0.2171 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0085 0.0312 0.029
Onchocerca volvulus 0.0369 0.1629 0.1606
Echinococcus granulosus neuropeptide Y receptor 0.0085 0.0312 0.029
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0057 0.0182 0.0647
Echinococcus multilocularis neuropeptide Y receptor 0.0085 0.0312 0.0301
Brugia malayi putative neuropeptide receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Echinococcus multilocularis g protein coupled receptor 0.0085 0.0312 0.0301
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0085 0.0312 0.029
Onchocerca volvulus Peroxidasin homolog 0.0672 0.3038 0.3019
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0399 0.177 0.1752
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0369 0.1629 0.161
Onchocerca volvulus 0.0672 0.3038 0.3019
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0085 0.0312 0.029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0284 0.1236 0.1236
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0182 0.0647
Echinococcus granulosus hypothetical protein 0.1567 0.7192 0.7186
Echinococcus multilocularis sodium and chloride dependent glycine 0.0369 0.1629 0.162
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0042 0.0112 0.0112
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0112 0.009
Schistosoma mansoni growth hormone secretagogue receptor 0.0085 0.0312 0.029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0085 0.0312 0.029
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0112 0.0572
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Onchocerca volvulus Pyruvate kinase homolog 0.0025 0.0036 0.0008
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Schistosoma mansoni lipoxygenase 0.0066 0.0225 0.0203
Brugia malayi Dopamine receptor protein 2 0.0085 0.0312 0.029
Onchocerca volvulus 0.0085 0.0312 0.0285
Brugia malayi hypothetical protein 0.0085 0.0312 0.029
Schistosoma mansoni hypothetical protein 0.0085 0.0312 0.029
Echinococcus granulosus rhodopsin orphan GPCR 0.0085 0.0312 0.029
Echinococcus multilocularis allatostatin A receptor 0.0085 0.0312 0.0301
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.004 0.0104 0.0332
Loa Loa (eye worm) G-protein coupled receptor 0.0085 0.0312 0.0312
Onchocerca volvulus 0.0085 0.0312 0.0285
Echinococcus multilocularis neuropeptides capa receptor 0.0085 0.0312 0.0301
Onchocerca volvulus 0.0058 0.0186 0.0159
Brugia malayi sulfakinin receptor protein 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Echinococcus granulosus tachykinin peptides receptor 99D 0.0085 0.0312 0.029
Mycobacterium ulcerans oxidoreductase 0.0042 0.0112 0.0338
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Onchocerca volvulus Dual oxidase homolog 0.0672 0.3038 0.3019
Loa Loa (eye worm) hypothetical protein 0.0369 0.1629 0.1629
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0057 0.0182 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Onchocerca volvulus 0.0672 0.3038 0.3019
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Echinococcus granulosus sodium and chloride dependent glycine 0.0369 0.1629 0.161
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Brugia malayi G-protein coupled receptor 0.0085 0.0312 0.029
Schistosoma mansoni myosin xvIII 0.0085 0.0312 0.029
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0005
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0066 0.0225 0.0203
Loa Loa (eye worm) neuropeptide F receptor 0.0085 0.0312 0.0312
Echinococcus granulosus neuropeptide FF receptor 2 0.0085 0.0312 0.029
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0085 0.0312 0.029
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0043 0.0115 0.0376
Brugia malayi hypothetical protein 0.0284 0.1236 0.1216
Echinococcus multilocularis survival motor neuron protein 1 0.0284 0.1236 0.1226
Schistosoma mansoni neuropeptide receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0369 0.1629 0.1629
Brugia malayi hypothetical protein 0.0085 0.0312 0.029
Brugia malayi Tachykinin-like peptides receptor 99D 0.0085 0.0312 0.029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0085 0.0312 0.029
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0085 0.0312 0.029
Schistosoma mansoni rab6-interacting 0.0024 0.0028 0.0005
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Echinococcus granulosus 7tm_1 domain containing protein 0.0085 0.0312 0.029
Loa Loa (eye worm) neuropeptide F receptor 0.0085 0.0312 0.0312
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0202 0.018
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0085 0.0312 0.029
Mycobacterium ulcerans pyruvate kinase 0.0025 0.0036 0.005
Onchocerca volvulus 0.0085 0.0312 0.0285
Onchocerca volvulus Peroxidase homolog 0.0672 0.3038 0.3019
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Onchocerca volvulus 0.2171 1 1
Loa Loa (eye worm) hypothetical protein 0.0361 0.1594 0.1594
Leishmania major pyruvate kinase 0.0025 0.0036 0.0085
Schistosoma mansoni neuropeptide F-like receptor 0.0085 0.0312 0.029
Onchocerca volvulus 0.0672 0.3038 0.3019
Schistosoma mansoni biogenic amine receptor 0.0085 0.0312 0.029
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0042 0.0112 0.009
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Echinococcus granulosus g-protein coupled receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) animal heme peroxidase 0.0672 0.3038 0.3038
Echinococcus multilocularis G-protein coupled receptor, putative 0.0085 0.0312 0.0301
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0085 0.0312 0.0301
Echinococcus granulosus rhodopsin orphan GPCR 0.0085 0.0312 0.029
Echinococcus multilocularis sodium and chloride dependent glycine 0.0369 0.1629 0.162
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0182 0.06
Echinococcus multilocularis neuropeptide receptor A26 0.0085 0.0312 0.0301
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Loa Loa (eye worm) blistered cuticle protein 3 0.0672 0.3038 0.3038
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0028 0.0005
Onchocerca volvulus 0.0085 0.0312 0.0285
Echinococcus granulosus somatostatin receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Brugia malayi Blistered cuticle protein 3 0.0672 0.3038 0.3022
Echinococcus granulosus peptide allatostatin:somatostatin 0.0085 0.0312 0.029
Echinococcus granulosus peroxidasin 0.0672 0.3038 0.3022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0085 0.0312 0.0301
Echinococcus granulosus rhodopsin orphan GPCR 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0042 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Entamoeba histolytica acyl-coA synthetase, putative 0.0057 0.0182 1
Toxoplasma gondii hypothetical protein 0.0369 0.1629 1
Onchocerca volvulus Pyruvate kinase homolog 0.0025 0.0036 0.0008
Brugia malayi AKH receptor 0.0085 0.0312 0.029
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0057 0.0182 1
Loa Loa (eye worm) pyruvate kinase 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Echinococcus multilocularis G protein coupled receptor 139 0.0085 0.0312 0.0301
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0112 0.009
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0112 0.0559
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0085 0.0312 0.0301
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0085 0.0312 0.0312
Mycobacterium ulcerans dehydrogenase 0.0042 0.0112 0.0338
Echinococcus granulosus mitogen activated protein kinase 3 0.0061 0.0202 0.018
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Schistosoma mansoni amine oxidase 0.0042 0.0112 0.009
Schistosoma mansoni adenoreceptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0202 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.0028
Trichomonas vaginalis pyruvate kinase, putative 0.0025 0.0036 0.0742
Echinococcus granulosus g protein coupled receptor 0.0085 0.0312 0.029
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0028 0.0017
Treponema pallidum sodium- and chloride- dependent transporter 0.2171 1 1
Onchocerca volvulus Pyruvate kinase homolog 0.0025 0.0036 0.0008
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0061 0.0202 0.1141
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0085 0.0312 0.0301
Echinococcus granulosus serotonin transporter 0.2171 1 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0057 0.0182 0.1015
Onchocerca volvulus Chorion peroxidase homolog 0.0672 0.3038 0.3019
Echinococcus granulosus neuropeptide receptor 0.0085 0.0312 0.029
Schistosoma mansoni amine GPCR 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Brugia malayi Doublecortin family protein 0.0024 0.0028 0.0005
Echinococcus multilocularis RUN 0.0024 0.0028 0.0017
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0085 0.0312 0.029
Echinococcus granulosus neuropeptide receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Echinococcus multilocularis orexin receptor type 2 0.0085 0.0312 0.0301
Schistosoma mansoni opsin-like receptor 0.0085 0.0312 0.029
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0085 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Trypanosoma brucei pyruvate kinase 1 0.0025 0.0036 0.0085
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Echinococcus multilocularis mitogen activated protein kinase 0.0061 0.0202 0.0191
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0028 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0202 1
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0042 0.0112 0.0338
Echinococcus granulosus microtubule associated protein 2 0.0828 0.3764 0.375
Loa Loa (eye worm) pyruvate kinase 0.0025 0.0036 0.0036
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0042 0.0112 0.0102
Mycobacterium ulcerans monoamine oxidase 0.0042 0.0112 0.0338
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Brugia malayi Dopamine receptor protein 1 0.0085 0.0312 0.029
Leishmania major UDP-galactopyranose mutase 0.0042 0.0112 0.0572
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.004 0.0104 0.0332
Brugia malayi follicle stimulating hormone receptor 0.0361 0.1594 0.1575
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0112 0.0365
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0369 0.1629 0.161
Echinococcus multilocularis microtubule associated protein 2 0.0828 0.3764 0.3758
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0085 0.0312 0.029
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0085 0.0312 0.0301
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0085 0.0312 0.0301
Schistosoma mansoni microtubule-associated protein tau 0.0828 0.3764 0.375
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0042 0.0112 0.009
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0061 0.0202 0.1141
Schistosoma mansoni survival motor neuron protein 0.0058 0.0186 0.0164
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0042 0.0112 0.0559
Leishmania major C-8 sterol isomerase-like protein 0.0361 0.1594 1
Trypanosoma cruzi pyruvate kinase 2, putative 0.0025 0.0036 0.0085
Brugia malayi hypothetical protein 0.0024 0.0028 0.0005
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0085 0.0312 0.029
Onchocerca volvulus 0.0085 0.0312 0.0285
Brugia malayi hypothetical protein 0.0085 0.0312 0.029
Echinococcus granulosus rhodopsin orphan GPCR 0.0085 0.0312 0.029
Schistosoma mansoni pyruvate kinase 0.0025 0.0036 0.0013
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0043 0.0115 0.0348
Loa Loa (eye worm) hypothetical protein 0.0043 0.0115 0.0115
Echinococcus multilocularis fmrfamide receptor 0.0085 0.0312 0.0301
Echinococcus multilocularis serotonin receptor 0.0595 0.2681 0.2673
Schistosoma mansoni amine GPCR 0.0085 0.0312 0.029
Schistosoma mansoni lipoxygenase 0.0024 0.0028 0.0005
Giardia lamblia Pyruvate kinase 0.0025 0.0036 0.0742
Onchocerca volvulus 0.0085 0.0312 0.0285
Loa Loa (eye worm) hypothetical protein 0.0042 0.0112 0.0112
Echinococcus granulosus pyruvate kinase 0.0025 0.0036 0.0013
Brugia malayi hypothetical protein 0.0085 0.0312 0.029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0085 0.0312 0.0301
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0085 0.0312 0.0312
Echinococcus multilocularis rhodopsin orphan GPCR 0.0085 0.0312 0.0301
Trypanosoma brucei C-8 sterol isomerase, putative 0.0361 0.1594 1
Echinococcus granulosus tm gpcr rhodopsin 0.0085 0.0312 0.029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0085 0.0312 0.0301
Schistosoma mansoni biogenic amine (5HT) receptor 0.0595 0.2681 0.2664
Plasmodium vivax acyl-CoA synthetase, putative 0.0043 0.0115 0.0577
Brugia malayi SWIRM domain containing protein 0.0042 0.0112 0.009
Echinococcus granulosus g protein coupled receptor 0.0085 0.0312 0.029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0369 0.1629 0.1629
Brugia malayi GnHR receptor homolog 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0369 0.1629 0.161
Brugia malayi Animal haem peroxidase family protein 0.0672 0.3038 0.3022
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0369 0.1629 0.161
Loa Loa (eye worm) hypothetical protein 0.0672 0.3038 0.3038
Onchocerca volvulus 0.0369 0.1629 0.1606
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0361 0.1594 1
Schistosoma mansoni neuropeptide F-like receptor 0.0085 0.0312 0.029
Brugia malayi hypothetical protein 0.0672 0.3038 0.3022
Echinococcus granulosus neuropeptides capa receptor 0.0085 0.0312 0.029
Schistosoma mansoni neuropeptide receptor 0.0085 0.0312 0.029
Schistosoma mansoni biogenic amine (5HT) receptor 0.0085 0.0312 0.029
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0057 0.0182 0.06
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0042 0.0112 0.5237
Brugia malayi neuropeptide F receptor 0.0085 0.0312 0.029
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0369 0.1629 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0369 0.1629 0.161
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0085 0.0312 0.029
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Loa Loa (eye worm) animal heme peroxidase 0.0672 0.3038 0.3038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0085 0.0312 0.0301
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0061 0.0202 0.1141
Leishmania major 4-coumarate:coa ligase-like protein 0.0057 0.0182 0.1015
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Onchocerca volvulus 0.0085 0.0312 0.0285
Loa Loa (eye worm) hypothetical protein 0.0085 0.0312 0.0312
Loa Loa (eye worm) G-protein coupled receptor 0.0085 0.0312 0.0312
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0061 0.0202 0.1141
Brugia malayi hypothetical protein 0.0085 0.0312 0.029
Brugia malayi G-protein coupled receptor 0.0085 0.0312 0.029

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.19 uM Inhibition of 5-HT uptake in synaptosomal preparation from rat corpus striatum, using [3H]-5-HT ChEMBL. 6492080
IC50 (functional) = 1.4 uM Inhibition of norepinephrine uptake in synaptosomal preparation fro rat hypothalamus, using [3H]-norepinephrine ChEMBL. 6492080
IC50 (functional) = 1.6 uM Inhibition of dopamine uptake in synaptosomal preparation in rat corpus striatum, using [3H]-dopamine ChEMBL. 6492080

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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