Detailed information for compound 541621

Basic information

Technical information
  • TDR Targets ID: 541621
  • Name: [(2S)-4,4-diethoxy-2-(hydroxymethyl)butyl] ac etate
  • MW: 234.289 | Formula: C11H22O5
  • H donors: 1 H acceptors: 2 LogP: 0.65 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(C[C@H](COC(=O)C)CO)OCC
  • InChi: 1S/C11H22O5/c1-4-14-11(15-5-2)6-10(7-12)8-16-9(3)13/h10-12H,4-8H2,1-3H3/t10-/m0/s1
  • InChiKey: UFSFOZXONNJSBH-JTQLQIEISA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • acetic acid [(2S)-4,4-diethoxy-2-(hydroxymethyl)butyl] ester
  • [(2S)-4,4-diethoxy-2-(hydroxymethyl)butyl] ethanoate
  • acetic acid [(2S)-4,4-diethoxy-2-methylol-butyl] ester
  • 2-(2,2-diethoxyethyl)-1,3-propanediol monoacetate
  • 134665-24-0
  • 2-Depdm
  • 1,3-Propanediol, 2-(2,2-diethoxyethyl)-, monoacetate, (S)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Toxoplasma gondii ABC1 family protein 0.0038 0.0062 0.0058
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0062 0.0053
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0114 0.0514
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0035 0.0054 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.005
Schistosoma mansoni smad1 5 8 and 0.0036 0.0057 0.0319
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0009 0.0003
Schistosoma mansoni RAR-like nuclear receptor 0.0035 0.0054 0.0302
Loa Loa (eye worm) hypothetical protein 0.0064 0.0132 0.0601
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0032 0.0046 0.0032
Echinococcus granulosus TGF beta signal transducer SmadC 0.0036 0.0057 0.0301
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0064 0.0357
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0074 0.0393
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0035 0.0054 0.0238
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0025
Loa Loa (eye worm) nuclear factor I 0.002 0.0015 0.0052
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0032 0.0046 0.0038
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0183 0.1
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0062 0.0634
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0089 0.0116
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0034
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0024 0.0026 0.0017
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0054 0.007
Brugia malayi paired box pox-meso protein 0.0016 0.0003 0.0015
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0025 0.001
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0064 0.0339
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0055 0.0253
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0025
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0047 0.024
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0123 0.0685
Brugia malayi Isocitrate dehydrogenase 0.0053 0.0104 0.0482
Brugia malayi beta-NAC-like protein 0.0078 0.0171 0.0795
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.006 0.0051
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0018 0.005
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0062 0.0287
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0054 0.0302
Onchocerca volvulus Protein ultraspiracle homolog 0.0035 0.0054 0.0238
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0074 0.0097
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0024 0.0027 0.0021
Echinococcus multilocularis nuclear receptor nhr 48 0.0016 0.0005 0.0003
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.0337 0.1853
Echinococcus granulosus GPCR family 2 0.0052 0.01 0.0537
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0053 0.0104 0.119
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0123 0.0685
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0163 0.0399 0.1844
Leishmania major DNA polymerase eta, putative 0.0064 0.0132 0.1569
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0018 0.0011 0.0034
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0062 0.0674
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Schistosoma mansoni hypothetical protein 0.0048 0.009 0.05
Echinococcus multilocularis mothers against decapentaplegic 5 0.0036 0.0057 0.0074
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0031 0.0044 0.0426
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0054 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0044 0.0426
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0005 0.0003
Schistosoma mansoni cpg binding protein 0.0093 0.021 0.1166
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0035 0.0054 0.0252
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.006 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0047 0.0258
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.006 0.0315
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0025 0.0016
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0014 0.006
Brugia malayi Steroid receptor seven-up type 2 0.0035 0.0054 0.0252
Mycobacterium tuberculosis Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.3745 1 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0035 0.0054 0.0284
Brugia malayi Thioredoxin reductase 0.0057 0.0114 0.0528
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0025 0.0139
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0031 0.0044 0.004
Echinococcus granulosus dnaJ subfamily B 0.0423 0.1095 0.6066
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0004 0.0005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0054 0.0284
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0052 0.01 0.0464
Schistosoma mansoni hypothetical protein 0.005 0.0095 0.0526
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0052 0.01 0.0537
Trypanosoma cruzi metacaspase 5, putative 0.0031 0.0044 0.0401
Brugia malayi nuclear hormone receptor 0.0016 0.0005 0.0024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0031 0.0044 0.0426
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0031 0.0044 0.0205
Brugia malayi isocitrate dehydrogenase 0.0053 0.0104 0.0482
Schistosoma mansoni smad 0.0016 0.0004 0.0024
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0052 0.01 0.0537
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0018 0.005
Trypanosoma brucei metacaspase MCA3 0.0031 0.0044 0.0401
Brugia malayi hypothetical protein 0.0358 0.0921 0.4279
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0062 0.0056
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0064 0.0667
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0025 0.0114
Brugia malayi MH2 domain containing protein 0.0036 0.0057 0.0266
Schistosoma mansoni paired box protein pax-6 0.0016 0.0003 0.0019
Brugia malayi hypothetical protein 0.0111 0.0259 0.1204
Echinococcus multilocularis FTZ F1 alpha 0.0035 0.0054 0.007
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0014 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0035 0.0054 0.0238
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0273
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0016 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0052
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0114 0.0613
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0057 0.03
Onchocerca volvulus 0.0016 0.0005 0.0009
Entamoeba histolytica hypothetical protein 0.0078 0.0171 0.7356
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0005 0.0029
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0053 0.0104 0.119
Toxoplasma gondii pantoate-beta-alanine ligase 0.3745 1 1
Loa Loa (eye worm) ICD-1 protein 0.0078 0.0171 0.0781
Loa Loa (eye worm) beta-lactamase 0.0038 0.0062 0.0273
Schistosoma mansoni coup transcription factor 0.0035 0.0054 0.0302
Mycobacterium ulcerans hypothetical protein 0.0038 0.0062 0.0053
Echinococcus multilocularis smad 0.0036 0.0057 0.0074
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0018 0.005
Schistosoma mansoni hypothetical protein 0.0041 0.007 0.0389
Entamoeba histolytica hypothetical protein 0.0036 0.0057 0.1678
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Loa Loa (eye worm) hypothetical protein 0.0042 0.0074 0.033
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0032 0.0046 0.004
Echinococcus multilocularis mothers against decapentaplegic 6 0.0016 0.0004 0.0001
Trypanosoma brucei transcription factor BTF3, putative 0.0078 0.0171 0.2084
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0024 0.0019
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0064 0.0667
Onchocerca volvulus 0.0035 0.0054 0.0238
Schistosoma mansoni Smad4 0.0016 0.0004 0.0024
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0014 0.001
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0024 0.0026 0.0011
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0026 0.0127
Mycobacterium ulcerans polyketide synthase 0.0032 0.0046 0.0038
Schistosoma mansoni hypothetical protein 0.0423 0.1095 0.6074
Brugia malayi Pre-SET motif family protein 0.0209 0.0522 0.2427
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0025
Toxoplasma gondii type I fatty acid synthase, putative 0.0033 0.0049 0.0044
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0031 0.0044 0.0426
Plasmodium falciparum basic transcription factor 3b, putative 0.0078 0.0171 0.649
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0024 0.0604
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0301 0.0768 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0035 0.0054 0.0252
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0138 0.0767
Brugia malayi beta-lactamase family protein 0.0038 0.0062 0.0287
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0144 0.0348 0.0342
Leishmania major DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Echinococcus granulosus nuclear receptor nhr 48 0.0016 0.0005 0.0011
Brugia malayi MH2 domain containing protein 0.0016 0.0004 0.0019
Echinococcus granulosus smad 0.0036 0.0057 0.0301
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0044 0.1426
Entamoeba histolytica hypothetical protein 0.0036 0.0057 0.1678
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0114 0.0108
Echinococcus granulosus dna polymerase eta 0.0064 0.0132 0.0717
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0035 0.0054 0.0302
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0025 0.0043
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0301 0.0768 1
Schistosoma mansoni smad 0.0036 0.0057 0.0319
Plasmodium vivax metacaspase 1, putative 0.0031 0.0044 0.1426
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0035 0.0054 0.0238
Trypanosoma cruzi transcription factor btf3, putative 0.0078 0.0171 0.2084
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0016 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0358 0.0921 0.4271
Schistosoma mansoni transcription factor btf3 0.0078 0.0171 0.0949
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.0337 0.0455
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Trypanosoma brucei metacaspase 0.0031 0.0044 0.0401
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0075 0.0804
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0075 0.0804
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0025 0.0028 0.0014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0013
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.0224 1
Trypanosoma brucei unspecified product 0.0027 0.0032 0.0242
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0032 0.0046 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0032 0.0242
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0053 0.0104 0.119
Brugia malayi TAR-binding protein 0.0066 0.0138 0.0642
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0054 0.007
Brugia malayi Cell death protein 3 precursor 0.0031 0.0044 0.0205
Toxoplasma gondii NAC domain-containing protein 0.0078 0.0171 0.0167
Brugia malayi conserved hypotetical protein 0.0016 0.0005 0.0024
Echinococcus granulosus mothers against decapentaplegic 5 0.0036 0.0057 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.005
Echinococcus granulosus caspase 8 0.0031 0.0044 0.0228
Loa Loa (eye worm) hypothetical protein 0.0035 0.0054 0.0238
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0114 0.4196
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0123 0.0164
Echinococcus multilocularis caspase 0.0031 0.0044 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Schistosoma mansoni hypothetical protein 0.0052 0.01 0.0554
Schistosoma mansoni hypothetical protein 0.0036 0.0057 0.0318
Plasmodium falciparum thioredoxin reductase 0.002 0.0014 0.022
Brugia malayi Latrophilin receptor protein 2 0.0052 0.01 0.0464
Brugia malayi Pre-SET motif family protein 0.0032 0.0047 0.0215
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0024 0.0128
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0016 0.0005 0.0024
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0025 0.0139
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0011 0.0048
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0034
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0032 0.0046 0.004
Plasmodium falciparum ataxin-2 like protein, putative 0.0111 0.0259 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0064 0.0083
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0062 0.0325
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0035 0.0054 0.0238
Plasmodium falciparum glutathione reductase 0.0057 0.0114 0.4196
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.005
Schistosoma mansoni survival motor neuron protein 0.0048 0.009 0.05
Trypanosoma brucei unspecified product 0.0027 0.0032 0.0242
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0062 0.0056
Schistosoma mansoni caspase-7 (C14 family) 0.0031 0.0044 0.0246
Schistosoma mansoni retinoic acid receptor RXR 0.0035 0.0054 0.0302
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0089 0.0116
Echinococcus multilocularis caspase 2 0.0031 0.0044 0.0056
Echinococcus multilocularis geminin 0.0549 0.1433 0.1948
Echinococcus multilocularis Smad4 0.0036 0.0057 0.0074
Plasmodium vivax basic transcription factor 3b, putative 0.0078 0.0171 0.649
Loa Loa (eye worm) inositol-1 0.0037 0.006 0.0264
Echinococcus multilocularis muscleblind protein 0.0328 0.0842 0.1142
Echinococcus multilocularis transcription factor eb 0.0107 0.025 0.0335
Echinococcus granulosus caspase 0.0031 0.0044 0.0228
Trichomonas vaginalis set domain proteins, putative 0.0238 0.0599 0.8258
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0142 0.0343 0.4363
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.003 0.0041 0.0191
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.005 0.0044
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0064 0.0083
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0273
Trypanosoma brucei unspecified product 0.0038 0.0064 0.0667
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0031 0.0044 0.004
Plasmodium falciparum thioredoxin reductase 0.0057 0.0114 0.4196
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0171 0.2217
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0025
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0064 0.0058
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0016 0.0005 0.0011
Entamoeba histolytica hypothetical protein 0.0036 0.0057 0.1678
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0031 0.0044 0.004
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0064 0.0284
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0041 0.0211
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0064 0.0709
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0038 0.0193
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0024 0.0015
Echinococcus granulosus FTZ F1 alpha 0.0035 0.0054 0.0284
Schistosoma mansoni hypothetical protein 0.0112 0.0261 0.1446
Loa Loa (eye worm) nuclear receptor NHR-67 0.0016 0.0005 0.0009
Toxoplasma gondii isocitrate dehydrogenase 0.0053 0.0104 0.01
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0031 0.0044 0.0228
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0062 0.0674
Leishmania major hypothetical protein, conserved 0.0111 0.0259 0.3251
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0138 0.0642
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0024 0.001
Schistosoma mansoni paired box protein pax-6 0.0016 0.0003 0.0019
Echinococcus granulosus neuropeptide receptor A26 0.0461 0.1196 0.6624
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0123 0.0117
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0034
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0044 0.0426
Brugia malayi glutathione reductase 0.0057 0.0114 0.0528
Loa Loa (eye worm) hypothetical protein 0.0052 0.01 0.0448
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.002 0.0014 0.3646
Echinococcus granulosus mothers against decapentaplegic 6 0.0016 0.0004 0.0005
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0014 0.022
Loa Loa (eye worm) CXXC zinc finger family protein 0.0093 0.021 0.0963
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0062 0.0634
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0053 0.0104 0.0098
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0053 0.0104 0.0558
Schistosoma mansoni DNA polymerase eta 0.0064 0.0132 0.0734
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0273
Brugia malayi beta-lactamase family protein 0.0038 0.0062 0.0287
Mycobacterium ulcerans lipase LipD 0.0038 0.0062 0.0053
Onchocerca volvulus 0.0032 0.0047 0.0201
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0047 0.0059
Trypanosoma cruzi PAB1-binding protein , putative 0.0111 0.0259 0.3251
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0123 0.0667
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0053 0.0104 0.119
Echinococcus granulosus caspase 2 0.0031 0.0044 0.0228
Schistosoma mansoni inositol monophosphatase 0.0037 0.006 0.0333
Echinococcus granulosus tar DNA binding protein 0.0066 0.0138 0.075
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0014 0.0079
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0062 0.0273
Schistosoma mansoni nuclear receptor 0.0016 0.0005 0.0029
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0062 0.0056
Echinococcus multilocularis transcription factor btf3 0.0078 0.0171 0.0229
Mycobacterium ulcerans polyketide synthase Pks9 0.002 0.0014 0.0006
Echinococcus multilocularis isocitrate dehydrogenase 0.0053 0.0104 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Echinococcus multilocularis neuropeptide receptor A26 0.0461 0.1196 0.1625
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0031 0.0044 0.0426
Loa Loa (eye worm) hypothetical protein 0.0083 0.0183 0.0838
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0035 0.0054 0.007
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0025 0.0016
Mycobacterium ulcerans pantoate--beta-alanine ligase 0.3745 1 1
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0064 0.0299
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0035 0.0054 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.005
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.009 0.0418
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.005
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0035 0.0054 0.0252
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Loa Loa (eye worm) steroid hormone receptor 0.0035 0.0054 0.0238
Brugia malayi hypothetical protein 0.0236 0.0593 0.2754
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0047 0.0042
Entamoeba histolytica hypothetical protein 0.0036 0.0057 0.1678
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.0191
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0183 0.0851
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0055 0.0239
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Onchocerca volvulus 0.0038 0.0062 0.0273
Trypanosoma cruzi metacaspase 5, putative 0.0031 0.0044 0.0401
Schistosoma mansoni hypothetical protein 0.0549 0.1433 0.7946
Brugia malayi Inositol-1 0.0037 0.006 0.0278
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0024 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0035 0.0054 0.0238
Mycobacterium ulcerans Type I modular polyketide synthase 0.003 0.0041 0.0033
Brugia malayi nuclear receptor NHR-88 0.0016 0.0005 0.0024
Leishmania major basic transcription factor 3a, putative 0.0078 0.0171 0.2084
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0035 0.0054 0.007
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0025 0.0016
Trypanosoma cruzi DNA polymerase eta, putative 0.0064 0.0132 0.1569
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0031 0.0044 0.0426
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0035 0.0054 0.0252
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0024 0.0604
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0064 0.0056
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0016 0.0005 0.0029
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0018 0.005
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0144 0.0348 0.0334
Schistosoma mansoni steroid hormone receptor ad4bp 0.0035 0.0054 0.0302
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.0224 0.1227
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0018 0.005
Onchocerca volvulus 0.0016 0.0005 0.0009
Echinococcus granulosus thyroid hormone receptor alpha 0.0016 0.0005 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0035 0.0054 0.0252
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0031 0.0044 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0025 0.001
Schistosoma mansoni paired box protein pax-6 0.0016 0.0003 0.0019
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0031 0.0044 0.0426
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0045 0.0081 0.0075
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0026 0.0145
Loa Loa (eye worm) glutaminase 2 0.0284 0.0723 0.3348
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0011 0.0059
Brugia malayi hypothetical protein 0.0018 0.0011 0.0048
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.0309 0.0303
Loa Loa (eye worm) Smad1 0.0036 0.0057 0.0252
Echinococcus multilocularis microtubule associated protein 2 0.0687 0.1804 0.2453
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0053 0.0104 0.0137
Brugia malayi ecdysteroid receptor 0.0035 0.0054 0.0252
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0035 0.0054 0.0252
Onchocerca volvulus Fatty acid synthase homolog 0.0054 0.0105 0.0475
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0061 0.0057
Leishmania major trypanothione reductase 0.0057 0.0114 0.1322
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0035 0.0054 0.0238
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0062 0.0056
Brugia malayi MH1 domain containing protein 0.002 0.0015 0.0067
Loa Loa (eye worm) hypothetical protein 0.0328 0.0842 0.3902
Brugia malayi Gooseberry protein 0.0016 0.0003 0.0015
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0031 0.0044 0.0246
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0035 0.0054 0.0302
Trypanosoma cruzi metacaspase, putative 0.0031 0.0044 0.0401
Schistosoma mansoni Smad4 0.0016 0.0004 0.0024
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0089 0.0398
Mycobacterium ulcerans hypothetical protein 0.0024 0.0025 0.0016
Loa Loa (eye worm) hypothetical protein 0.0098 0.0224 0.1028
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0144 0.0348 0.0342
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0019 0.0013 0.0009
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0089 0.0412
Mycobacterium ulcerans thioesterase 0.0025 0.0028 0.0019
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0064 0.0667
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0024 0.0019
Brugia malayi MH1 domain containing protein 0.0036 0.0057 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0074 0.0847
Trichomonas vaginalis esterase, putative 0.0038 0.0062 0.0674
Onchocerca volvulus 0.0038 0.0062 0.0273
Plasmodium falciparum metacaspase 1 0.0031 0.0044 0.1426
Trypanosoma brucei trypanothione reductase 0.0057 0.0114 0.1322
Loa Loa (eye worm) transcription factor SMAD2 0.0526 0.1372 0.6369
Loa Loa (eye worm) hypothetical protein 0.0317 0.0812 0.3764
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0029 0.0039 0.0033
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0005 0.0024
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0035 0.0054 0.0302
Loa Loa (eye worm) glutaminase 0.0284 0.0723 0.3348
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0025 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0171 0.2217
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0099
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.01 0.1133
Brugia malayi Pax transcription factor protein 2 0.0817 0.2152 1
Brugia malayi RNA binding protein 0.0066 0.0138 0.0642
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0052 0.01 0.0132
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0064 0.0357
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0035 0.0054 0.007
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0062 0.0056
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0035 0.0054 0.0302
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0074 0.033
Schistosoma mansoni nuclear receptor nhr-48 0.0016 0.0005 0.0029
Mycobacterium leprae Polyketide synthase Pks13 0.0045 0.0081 0.0067
Brugia malayi ImpB/MucB/SamB family protein 0.0064 0.0132 0.0615
Echinococcus multilocularis dna polymerase eta 0.0064 0.0132 0.0176
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0018 0.0011 0.004
Schistosoma mansoni paired box protein pax-1-related 0.0016 0.0003 0.0019
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0018 0.0011 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0032 0.0242
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0005 0.0024
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0089 0.0474
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.006 0.0608
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.003 0.0041 0.0027
Brugia malayi 'Paired box' domain containing protein 0.0016 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0107 0.025 0.1159
Echinococcus granulosus muscleblind protein 0.0328 0.0842 0.4656
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0053 0.0104 0.3802
Loa Loa (eye worm) hypothetical protein 0.0035 0.0054 0.0238
Mycobacterium ulcerans Type I modular polyketide synthase 0.003 0.0041 0.0033
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0005 0.0011
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.004 0.0187
Toxoplasma gondii thioredoxin reductase 0.0057 0.0114 0.0109
Trypanosoma cruzi metacaspase, putative 0.0031 0.0044 0.0401
Loa Loa (eye worm) pax transcription factor protein 2 0.0817 0.2152 1
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.005
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0114 0.1322
Loa Loa (eye worm) isocitrate dehydrogenase 0.0053 0.0104 0.0468
Trypanosoma brucei PAB1-binding protein , putative 0.0111 0.0259 0.3251
Mycobacterium tuberculosis Conserved protein 0.0038 0.0062 0.0056
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0089 0.0474
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0025 0.0019
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.002 0.0014 0.0006
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.003 0.0041 0.0035
Mycobacterium tuberculosis Possible penicillin-binding protein 0.024 0.0604 0.0598
Schistosoma mansoni nuclear hormone receptor 0.0035 0.0054 0.0302
Echinococcus granulosus expressed conserved protein 0.0092 0.0208 0.1138
Schistosoma mansoni microtubule-associated protein tau 0.0687 0.1804 1
Echinococcus multilocularis GPCR, family 2 0.0052 0.01 0.0132
Echinococcus granulosus mothers against decapentaplegic 2 0.0016 0.0004 0.0005
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0052 0.01 0.0132
Schistosoma mansoni Smad4 0.0036 0.0057 0.0319
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0014 0.0006
Loa Loa (eye worm) MH2 domain-containing protein 0.0526 0.1372 0.6369
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0014 0.022
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0005 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.005
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0057 0.0318
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0036 0.0057 0.0319
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Plasmodium falciparum glutathione reductase 0.002 0.0014 0.022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0047 0.0258
Onchocerca volvulus 0.0083 0.0183 0.0838
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0035 0.0054 0.0238
Plasmodium falciparum ataxin-2 like protein, putative 0.0111 0.0259 1
Schistosoma mansoni cpg binding protein 0.0098 0.0224 0.1244
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0035 0.0055 0.0049
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0273
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0138 0.0628
Entamoeba histolytica transcription factor BTF3, putative 0.0078 0.0171 0.7356
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0016 0.0004 0.0005
Echinococcus multilocularis cpg binding protein 0.0098 0.0224 0.0301
Brugia malayi MH1 domain containing protein 0.0036 0.0057 0.0266
Brugia malayi orphan nuclear receptor NR2E1 0.0016 0.0005 0.0024
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0138 0.0767
Loa Loa (eye worm) hypothetical protein 0.0052 0.01 0.045
Schistosoma mansoni nuclear receptor 0.0016 0.0005 0.0029
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0061 0.0626
Echinococcus granulosus geminin 0.0549 0.1433 0.7942
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0053 0.0104 0.119
Onchocerca volvulus Bile acid receptor homolog 0.0035 0.0054 0.0238
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.003 0.0041 0.0035
Mycobacterium tuberculosis Probable thioesterase TesA 0.0025 0.0028 0.0022
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0025 0.0019
Echinococcus granulosus microtubule associated protein 2 0.0687 0.1804 1
Brugia malayi MH2 domain containing protein 0.0526 0.1372 0.6374
Onchocerca volvulus 0.0035 0.0055 0.0239
Mycobacterium ulcerans hypothetical protein 0.0158 0.0386 0.0378
Leishmania major hypothetical protein, conserved 0.0038 0.0062 0.0634
Trypanosoma cruzi transcription factor btf3, putative 0.0078 0.0171 0.2084
Schistosoma mansoni caspase-3 (C14 family) 0.0031 0.0044 0.0246
Brugia malayi Calcitonin receptor-like protein seb-1 0.0163 0.0399 0.1856
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0062 0.0343
Brugia malayi CXXC zinc finger family protein 0.0093 0.021 0.0976
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.0228 0.1266
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0024 0.0026 0.0017
Brugia malayi Smad1 0.0036 0.0057 0.0266
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0035 0.0054 0.0284
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0032 0.0242
Echinococcus granulosus transcription factor eb 0.0107 0.025 0.1368
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.0191
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0026 0.0031
Brugia malayi MH2 domain containing protein 0.0036 0.0057 0.0266
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0025 0.0016
Loa Loa (eye worm) RNA binding protein 0.0066 0.0138 0.0628
Toxoplasma gondii isocitrate dehydrogenase 0.0053 0.0104 0.01
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.006 0.0646
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0035 0.0054 0.0252
Loa Loa (eye worm) hypothetical protein 0.0035 0.0054 0.0238
Mycobacterium ulcerans beta-lactamase 0.0038 0.0062 0.0053
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Brugia malayi tailless protein 0.0016 0.0005 0.0024
Onchocerca volvulus 0.0238 0.0599 0.2773
Trichomonas vaginalis glutaminase, putative 0.0284 0.0723 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.0259 0.1191
Mycobacterium ulcerans Type I modular polyketide synthase 0.003 0.0041 0.0033
Echinococcus granulosus transcription factor btf3 0.0078 0.0171 0.0933
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.0224 0.1041
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0024 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0031 0.0044 0.0426
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0138 0.0184
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0053 0.0104 0.0137
Schistosoma mansoni hypothetical protein 0.0549 0.1433 0.7946
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0031 0.0044 0.0426
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.006 0.0646
Mycobacterium ulcerans polyketide synthase 0.003 0.0041 0.0033
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.0593 0.0803
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.0343 0.4363
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0123 0.0115
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0062 0.0674
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0053 0.0104 0.3802
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2753 0.7342 1
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0123 0.0119
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.0309 0.0303
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0016 0.0005 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0089 0.0492
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0053 0.0104 0.0137
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0062 0.0056
Mycobacterium ulcerans thioesterase TesA 0.0025 0.0028 0.0019
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0035 0.0054 0.0284
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0026 0.0031
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.003 0.0041 0.0035
Loa Loa (eye worm) hypothetical protein 0.0035 0.0054 0.0238
Onchocerca volvulus 0.0024 0.0025 0.0099
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0062 0.0674
Loa Loa (eye worm) histone methyltransferase 0.003 0.0041 0.0177
Brugia malayi nuclear receptor RXR 0.0018 0.0011 0.0048
Brugia malayi nuclear hormone receptor family member odr-7 0.0016 0.0005 0.0024
Onchocerca volvulus 0.0059 0.0119 0.0538
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0047 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0171 0.2217
Mycobacterium ulcerans glutaminase 0.0284 0.0723 0.0715
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.0593 0.3274
Onchocerca volvulus 0.0358 0.0921 0.4271
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0024 1
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0032 0.0046 0.0038
Echinococcus multilocularis neuropeptide s receptor 0.0461 0.1196 0.1625
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0138 0.0767
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0047 0.0258
Brugia malayi latrophilin 2 splice variant baaae 0.0112 0.0261 0.1212
Schistosoma mansoni smad1 5 8 and 0.0036 0.0057 0.0319
Onchocerca volvulus Cell death protein 3 homolog 0.0031 0.0044 0.0191
Loa Loa (eye worm) fatty acid synthase 0.0029 0.004 0.0172
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0183 0.0245
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0033 0.0446
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0075 0.0804
Schistosoma mansoni inositol monophosphatase 0.0037 0.006 0.0333
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0123 0.0115
Trypanosoma brucei Metacaspase-4 0.0031 0.0044 0.0401
Schistosoma mansoni zinc finger protein 0.0016 0.0005 0.0029
Echinococcus multilocularis expressed conserved protein 0.0092 0.0208 0.0279
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0024 0.0128
Onchocerca volvulus 0.0093 0.021 0.0963
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0062 0.0634
Schistosoma mansoni glutaminase 0.0284 0.0723 0.4006
Mycobacterium ulcerans polyketide synthase Pks13 0.0045 0.0081 0.0072
Loa Loa (eye worm) hypothetical protein 0.0107 0.0248 0.1139
Schistosoma mansoni hypothetical protein 0.0052 0.01 0.0554
Loa Loa (eye worm) latrophilin receptor protein 2 0.0052 0.01 0.045
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0018 0.0011 0.001
Schistosoma mansoni caspase-7 (C14 family) 0.0031 0.0044 0.0246
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0047 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0044 0.0426
Loa Loa (eye worm) nuclear hormone receptor 0.0016 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0163 0.0399 0.1844
Brugia malayi photoreceptor-specific nuclear receptor 0.0317 0.0812 0.3773
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0123 0.0115
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.0309 0.0303
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0025 0.0016
Brugia malayi hypothetical protein 0.0072 0.0154 0.0713
Loa Loa (eye worm) MH1 domain-containing protein 0.0036 0.0057 0.0252
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.006 0.0646
Plasmodium falciparum metacaspase-like protein 0.0031 0.0044 0.1426
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0062 0.008
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0036 0.0057 0.0074
Brugia malayi beta-lactamase 0.0038 0.0062 0.0287
Echinococcus granulosus Smad4 0.0036 0.0057 0.0301
Trichomonas vaginalis helicase, putative 0.0021 0.0018 0.005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0089 0.0492
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0014 0.0006
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0062 0.0053
Brugia malayi 'Paired box' domain containing protein 0.0016 0.0003 0.0015
Brugia malayi CHE-14 protein 0.0042 0.0074 0.0344
Trypanosoma cruzi metacaspase, putative 0.0031 0.0044 0.0401
Loa Loa (eye worm) MH2 domain-containing protein 0.0036 0.0057 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0044 0.0426
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Loa Loa (eye worm) hypothetical protein 0.0236 0.0593 0.2743
Loa Loa (eye worm) hypothetical protein 0.0032 0.0047 0.0201
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0183 0.1016
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0021 0.0019 0.0013
Brugia malayi nuclear receptor RXR 0.0016 0.0005 0.0024
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.005 0.0095 0.0125
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.006 0.0077
Brugia malayi nuclear receptor NHR-67 0.0016 0.0005 0.0024
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.0343 0.4363
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.006 0.1805
Schistosoma mansoni thyroid hormone receptor 0.0035 0.0054 0.0302
Echinococcus multilocularis protein patched 0.0042 0.0074 0.0097
Echinococcus granulosus neuropeptide s receptor 0.0461 0.1196 0.6624
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0034
Mycobacterium tuberculosis Probable reductase 0.013 0.0309 0.0303
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0035 0.0054 0.0284
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0014 0.022
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0024 0.21
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0053 0.0104 0.0137
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0041 0.0052
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.0309 0.0303
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.006 0.0608
Brugia malayi nuclear receptor NHR-88 0.0035 0.0054 0.0252
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0014 0.022
Brugia malayi hypothetical protein 0.0016 0.0005 0.0024
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0074 0.0393
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0035 0.0054 0.0252
Loa Loa (eye worm) hypothetical protein 0.0035 0.0054 0.0238
Brugia malayi 'Paired box' domain containing protein 0.0016 0.0003 0.0015
Mycobacterium tuberculosis Conserved hypothetical protein 0.0158 0.0386 0.038
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0044 0.0426
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0014 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0035 0.0054 0.0252
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0011 0.0048
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0035 0.0054 0.0252
Schistosoma mansoni cpg binding protein 0.0098 0.0224 0.1244
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0062 0.0048
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Plasmodium vivax SET domain protein, putative 0.0032 0.0047 0.1511
Onchocerca volvulus 0.0048 0.009 0.0404
Loa Loa (eye worm) glutathione reductase 0.0057 0.0114 0.0514
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0054 0.0284
Leishmania major metacaspase, putative 0.0031 0.0044 0.0401
Trypanosoma brucei metacaspase MCA2 0.0031 0.0044 0.0401
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0018 0.005
Toxoplasma gondii histone lysine methyltransferase SET1 0.0177 0.0436 0.0432
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.006 0.0608
Echinococcus multilocularis protein dispatched 1 0.0048 0.009 0.0118
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0016 0.0005 0.0029
Mycobacterium tuberculosis Conserved protein 0.0038 0.0062 0.0056
Loa Loa (eye worm) hypothetical protein 0.0035 0.0054 0.0238
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0035 0.0054 0.007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0026 0.0127
Brugia malayi glutaminase DH11.1 0.0284 0.0723 0.3358
Schistosoma mansoni smad1 5 8 and 0.0036 0.0057 0.0319
Brugia malayi nuclear hormone receptor family member nhr-6 0.0016 0.0005 0.0024
Brugia malayi Muscleblind-like protein 0.0328 0.0842 0.3911
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0004 0.0005
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0064 0.0056
Trypanosoma brucei metacaspase 5, putative 0.0031 0.0044 0.0401
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0301 0.0768 1
Toxoplasma gondii hypothetical protein 0.0049 0.0091 0.0087
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0045 0.0081 0.0075
Schistosoma mansoni thyroid hormone receptor 0.0035 0.0054 0.0302
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0053 0.0104 0.0576
Loa Loa (eye worm) hypothetical protein 0.0035 0.0054 0.0238
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Brugia malayi steroid hormone receptor 0.0035 0.0054 0.0252
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0018 0.005
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0035 0.0054 0.0284
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0089 0.0492
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0025 0.0114
Echinococcus multilocularis thyroid hormone receptor alpha 0.0035 0.0054 0.007
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0075 0.0804
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0064 0.0667
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0005 0.0003
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0017 0.0007 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0044 0.0426
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0025 0.0016
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0064 0.0709
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0062 0.0343
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0138 0.0767
Brugia malayi mothers against decapentaplegic homolog 3 0.0016 0.0004 0.0019
Brugia malayi hypothetical protein 0.0018 0.0011 0.0048
Echinococcus granulosus dna polymerase kappa 0.0038 0.0064 0.0339
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0198 0.0492 0.2729
Schistosoma mansoni hypothetical protein 0.0041 0.007 0.0389
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0138 0.0767
Schistosoma mansoni hypothetical protein 0.0052 0.01 0.0554
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0005 0.0029
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.005 0.0035
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.006 0.0608
Loa Loa (eye worm) hypothetical protein 0.0051 0.0098 0.0441
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.006 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0099
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0064 0.0058
Toxoplasma gondii LsmAD domain-containing protein 0.0111 0.0259 0.0255
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0064 0.2027
Mycobacterium tuberculosis Probable oxidoreductase 0.0144 0.0348 0.0342
Loa Loa (eye worm) hypothetical protein 0.0112 0.0261 0.1199
Brugia malayi MH1 domain containing protein 0.002 0.0015 0.0067
Loa Loa (eye worm) hypothetical protein 0.0328 0.0842 0.3902
Schistosoma mansoni hypothetical protein 0.0041 0.007 0.0389
Echinococcus granulosus cpg binding protein 0.0098 0.0224 0.1228
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0056 0.0113 0.0523
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.0224 0.0301
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0032 0.0046 0.0032
Plasmodium vivax glutathione reductase, putative 0.0057 0.0114 0.4196
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0035 0.0054 0.0252
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0123 0.1451
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.003 0.0041 0.0033
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0273
Brugia malayi vab-3 gene. 0.0016 0.0003 0.0015
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0031 0.0044 0.0426
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.005 0.0095 0.0509
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0163 0.0399 0.1856
Brugia malayi nuclear hormone receptor 0.0035 0.0054 0.0252
Echinococcus multilocularis mothers against decapentaplegic 2 0.0016 0.0004 0.0001
Brugia malayi hypothetical protein 0.0036 0.0057 0.0266
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0025 0.0139
Giardia lamblia DINP protein human, muc B family 0.0038 0.0064 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0035 0.0054 0.0252
Trypanosoma cruzi metacaspase, putative 0.0031 0.0044 0.0401
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0035 0.0054 0.0302
Mycobacterium leprae Probable polyketide synthase Pks1 0.0032 0.0046 0.0032
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0005 0.0011
Loa Loa (eye worm) DR-78 0.0016 0.0005 0.0009
Toxoplasma gondii type I fatty acid synthase, putative 0.0021 0.0018 0.0014
Mycobacterium leprae Probable lipase LipE 0.0038 0.0062 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.005
Trypanosoma brucei DNA polymerase eta, putative 0.0064 0.0132 0.1569
Mycobacterium tuberculosis Conserved protein 0.0038 0.0062 0.0056
Brugia malayi ecdysone receptor 0.0016 0.0005 0.0024
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.0309 0.0295
Echinococcus multilocularis muscleblind protein 1 0.0328 0.0842 0.1142
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.0309 0.0303
Echinococcus multilocularis dnaJ subfamily B 0.0423 0.1095 0.1488
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0064 0.0667
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0029 0.0039 0.0033
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0057 0.0074
Schistosoma mansoni hypothetical protein 0.0052 0.01 0.0554
Brugia malayi hypothetical protein 0.0016 0.0005 0.0024
Trypanosoma cruzi PAB1-binding protein , putative 0.0111 0.0259 0.3251
Brugia malayi paired box protein 0.0016 0.0003 0.0015
Onchocerca volvulus 0.0817 0.2152 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0099
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0005 0.0009
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0014 0.001
Echinococcus multilocularis ecdysone induced protein 78C 0.0035 0.0054 0.007
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Plasmodium vivax ataxin-2 like protein, putative 0.0111 0.0259 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0114 0.015
Onchocerca volvulus 0.0038 0.0062 0.0273
Leishmania major DNA polymerase eta, putative 0.0037 0.0061 0.0626
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.0522 0.2416
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0025 0.0114
Echinococcus granulosus ecdysone induced protein 78C 0.0035 0.0054 0.0284
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0107 0.0248 0.1139
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0138 0.0628
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0273
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0025
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.003 0.0041 0.0027
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0009
Leishmania major mitochondrial DNA polymerase beta 0.0301 0.0768 1
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0062 0.2126
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0018 0.005
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0014 0.0008
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0025 0.0016
Schistosoma mansoni hypothetical protein 0.0041 0.007 0.0389
Schistosoma mansoni patched 1 0.0042 0.0074 0.0411
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0005 0.0003
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0024 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0062 0.0674
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0005 0.0011
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0062 0.0056
Echinococcus multilocularis caspase 8 0.0031 0.0044 0.0056

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.