Detailed information for compound 542090

Basic information

Technical information
  • TDR Targets ID: 542090
  • Name: methyl (2S)-2-[(3S)-3-benzyl-2-oxo-piperazin- 1-yl]-3-phenyl-propanoate
  • MW: 352.427 | Formula: C21H24N2O3
  • H donors: 1 H acceptors: 2 LogP: 3 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)[C@@H](N1CCN[C@H](C1=O)Cc1ccccc1)Cc1ccccc1
  • InChi: 1S/C21H24N2O3/c1-26-21(25)19(15-17-10-6-3-7-11-17)23-13-12-22-18(20(23)24)14-16-8-4-2-5-9-16/h2-11,18-19,22H,12-15H2,1H3/t18-,19-/m0/s1
  • InChiKey: ASHDRQJEJVMZJK-OALUTQOASA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-[(3S)-3-benzyl-2-oxo-1-piperazinyl]-3-phenylpropanoic acid methyl ester
  • methyl (2S)-2-[(3S)-2-oxo-3-(phenylmethyl)piperazin-1-yl]-3-phenyl-propanoate
  • (2S)-2-[(3S)-3-benzyl-2-keto-piperazino]-3-phenyl-propionic acid methyl ester
  • methyl (2S)-2-[(3S)-3-benzyl-2-oxopiperazin-1-yl]-3-phenylpropanoate
  • methyl 3-phenyl-3-(2'-oxo-3'-benzyl-1'-piperazinyl)propionate
  • methyl (2S)-2-[(3S)-2-oxo-3-(phenylmethyl)piperazin-1-yl]-3-phenylpropanoate
  • (2S)-2-[(3S)-2-oxo-3-(phenylmethyl)-1-piperazinyl]-3-phenylpropanoic acid methyl ester
  • (2S)-2-[(3S)-3-(benzyl)-2-keto-piperazin-1-yl]-3-phenyl-propionic acid methyl ester
  • 135884-98-9
  • Eff-och3
  • 1-Piperazineacetic acid, 2-oxo-alpha,3-bis(phenylmethyl)-, methyl ester, (S-(R*,R*))-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major importin beta-1 subunit, putative 0.0024 0.0104 0.0296
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0028 0.002
Echinococcus granulosus microtubule associated protein 2 0.0727 0.5798 0.6988
Brugia malayi nuclear hormone receptor family member nhr-6 0.0073 0.0504 0.1036
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0087 0.0092
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0104 0.0085
Brugia malayi photoreceptor-specific nuclear receptor 0.0155 0.1169 0.2483
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.006 0.0392 0.0373
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0161 0.0546
Echinococcus granulosus hypothetical protein 0.0015 0.0028 0.002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0167 0.0728
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0052 0.0077
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0225 0.0225
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0042 0.025 0.0748
Echinococcus multilocularis microtubule associated protein 2 0.0727 0.5798 0.6988
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0082 0.0575 0.0682
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0087 0.0187
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0167 0.0574
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.2214 0.2199
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0086 0.0376
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0075 0.0516 0.061
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0161 0.0701
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0433 0.0935
Brugia malayi heat shock protein 90 0.0102 0.0739 0.1548
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Onchocerca volvulus 0.0073 0.0504 0.1605
Schistosoma mansoni endoplasmin 0.0102 0.0739 0.1085
Mycobacterium tuberculosis Possible two component sensor kinase 0.0021 0.0079 0.0065
Brugia malayi Nuclear hormone receptor E75 0.0073 0.0504 0.1036
Entamoeba histolytica hypothetical protein 0.0075 0.0516 0.0516
Brugia malayi orphan nuclear receptor NR2E1 0.0073 0.0504 0.1036
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0155 0.1169 0.2483
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0155 0.1169 0.2528
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0281 0.2189 0.2631
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0084 0.0588 0.1272
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0021 0.0079 0.0059
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Trypanosoma brucei heat shock protein 90, putative 0.0102 0.0739 0.3103
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0155 0.1169 0.2483
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0235 0.027
Onchocerca volvulus 0.006 0.0395 0.1236
Trypanosoma cruzi ISWI complex protein 0.0016 0.0038 0.0163
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0697 0.0829
Schistosoma mansoni tar DNA-binding protein 0.0582 0.4626 0.679
Chlamydia trachomatis DNA gyrase subunit B 0.0021 0.0079 0.2453
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0161 0.0182
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0028 0.002
Entamoeba histolytica hypothetical protein 0.0181 0.1377 0.1377
Brugia malayi beta-lactamase family protein 0.0111 0.0811 0.1704
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.1169 0.2002
Echinococcus granulosus tar DNA binding protein 0.0582 0.4626 0.5572
Plasmodium falciparum heat shock protein 90 0.0102 0.0739 0.5194
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0161 0.117
Schistosoma mansoni neuropeptide receptor 0.0015 0.0028 0.004
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0111 0.0811 0.1589
Schistosoma mansoni amine GPCR 0.0015 0.0028 0.004
Echinococcus multilocularis RUN 0.0079 0.0547 0.0647
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0021 0.0079 0.006
Trypanosoma cruzi heat shock protein, putative 0.0042 0.025 0.1086
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0073 0.0504 0.1036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0028 0.004
Treponema pallidum heat shock protein 90 0.0082 0.057 0.057
Trypanosoma brucei heat shock protein, putative 0.0102 0.0739 0.3103
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0317 0.0685
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.006 0.0097
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0161 0.0182
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.0028 0.002
Mycobacterium tuberculosis Probable lipase LipE 0.0111 0.0811 0.1366
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Trichomonas vaginalis heat shock protein, putative 0.0082 0.057 0.0552
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0167 0.0148
Trichomonas vaginalis receptor histidine kinase, putative 0.0021 0.0079 0.0059
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0111 0.0811 0.1366
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0028 0.006
Brugia malayi PHD-finger family protein 0.0029 0.0145 0.0256
Echinococcus granulosus Polycystic kidney disease protein 0.0079 0.0547 0.0647
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0317 0.0369
Onchocerca volvulus 0.0155 0.1169 0.3846
Brugia malayi hypothetical protein 0.0097 0.0696 0.1454
Trypanosoma cruzi transcription factor btf3, putative 0.0181 0.1377 0.599
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.015 0.0497
Loa Loa (eye worm) hypothetical protein 0.0111 0.0811 0.1753
Loa Loa (eye worm) hypothetical protein 0.0084 0.0588 0.1272
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0028 0.002
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0582 0.4626 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.002 0.000000000073056
Loa Loa (eye worm) hypothetical protein 0.0111 0.0811 0.1753
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0087 0.0377
Echinococcus granulosus Nuclear hormone receptor HR96 0.0073 0.0504 0.0596
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0155 0.1169 0.1399
Echinococcus granulosus nuclear receptor nhr 48 0.0073 0.0504 0.0596
Giardia lamblia NADH oxidase lateral transfer candidate 0.0032 0.0167 0.0108
Loa Loa (eye worm) hypothetical protein 0.0155 0.1169 0.2528
Toxoplasma gondii DNA topoisomerase 2, putative 0.0021 0.0079 0.0572
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0237 0.0274
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0167 0.0189
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0242 0.0906
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Schistosoma mansoni biogenic amine receptor 0.0015 0.0028 0.004
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0082 0.057 0.0676
Schistosoma mansoni tar DNA-binding protein 0.0582 0.4626 0.679
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0028 0.002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0167 0.0574
Schistosoma mansoni nuclear receptor nhr-48 0.0073 0.0504 0.074
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0021 0.0079 0.006
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0167 0.1215
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Schistosoma mansoni heat shock protein 0.0042 0.025 0.0367
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0306 0.0449
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0433 0.0635
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0028 0.002
Schistosoma mansoni rab6-interacting 0.0079 0.0547 0.0802
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.2214 0.2199
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 1 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.0028 0.002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0167 0.0574
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0161 0.029
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0811 0.0793
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0161 0.0211
Echinococcus multilocularis thioredoxin glutathione reductase 0.0092 0.0657 0.078
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0316 0.2472 0.5344
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0167 0.0728
Onchocerca volvulus 0.0051 0.0321 0.099
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0021 0.0079 0.0065
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0021 0.0079 0.0343
Trichomonas vaginalis endoplasmin, putative 0.0063 0.0419 0.04
Loa Loa (eye worm) hypothetical protein 0.0039 0.0225 0.0486
Toxoplasma gondii thioredoxin reductase 0.0092 0.0653 0.474
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0155 0.1169 0.1399
Echinococcus multilocularis dna polymerase kappa 0.006 0.0392 0.046
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0436 0.0513
Mycobacterium tuberculosis Probable two component sensor kinase 0.0021 0.0079 0.0065
Schistosoma mansoni nuclear hormone receptor 0.0155 0.1169 0.1717
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0097 0.0152
Loa Loa (eye worm) hypothetical protein 0.004 0.023 0.0497
Loa Loa (eye worm) hypothetical protein 0.0039 0.0225 0.0487
Plasmodium vivax heat shock protein 90, putative 0.0042 0.025 0.1813
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0697 0.1023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0028 0.004
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Echinococcus granulosus thyroid hormone receptor alpha 0.0073 0.0504 0.0596
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0082 0.0575 0.0844
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0392 0.1567
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0711 0.5667 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0159 0.1196 0.2585
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0097 0.0099
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.0028 0.006
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0087 0.0629
Loa Loa (eye worm) hypothetical protein 0.0369 0.29 0.6268
Trichomonas vaginalis conserved hypothetical protein 0.0181 0.1377 0.136
Giardia lamblia Pms1-like protein 0.0021 0.0079 0.0019
Leishmania major DNA polymerase kappa, putative 0.006 0.0392 0.1567
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0087 0.0129
Schistosoma mansoni neuropeptide receptor 0.0015 0.0028 0.004
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0155 0.1169 0.1717
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0273 0.0535
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0167 0.1215
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0167 0.0728
Trypanosoma brucei heat shock protein, putative 0.0102 0.0739 0.3103
Schistosoma mansoni hypothetical protein 0.005 0.0317 0.0465
Schistosoma mansoni hypothetical protein 0.005 0.0317 0.0465
Plasmodium vivax heat shock protein, putative 0.0042 0.025 0.1813
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0155 0.1169 0.2483
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0028 0.002
Loa Loa (eye worm) thioredoxin reductase 0.0092 0.0653 0.1411
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0811 0.3527
Trypanosoma cruzi heat shock protein 90, putative 0.0082 0.057 0.2481
Trypanosoma brucei heat shock protein, putative 0.0102 0.0739 0.3103
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0235 0.0507
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0021 0.0079 0.0065
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0697 0.0829
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.006 0.0097
Loa Loa (eye worm) RecQ helicase 0.0022 0.0087 0.0187
Trypanosoma brucei heat shock protein, putative 0.0102 0.0739 0.3103
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0167 0.0304
Schistosoma mansoni hypothetical protein 0.0015 0.0028 0.004
Leishmania major basic transcription factor 3a, putative 0.0181 0.1377 0.5923
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0167 0.0728
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0028 0.002
Treponema pallidum NADH oxidase 0.0032 0.0167 0.0167
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0164 0.024
Trypanosoma cruzi Heat shock protein 83, putative 0.0102 0.0739 0.3215
Schistosoma mansoni cpg binding protein 0.006 0.0395 0.0579
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0028 0.002
Schistosoma mansoni survival motor neuron protein 0.0051 0.0321 0.0472
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Leishmania major hypothetical protein, conserved 0.0021 0.0079 0.0183
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Brugia malayi polk-prov protein 0.0018 0.006 0.0069
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.2214 0.2199
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0021 0.0079 0.0343
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0155 0.1169 0.2483
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0028 0.002
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.0028 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0433 0.1747
Onchocerca volvulus Bile acid receptor homolog 0.0155 0.1169 0.3846
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0155 0.1169 0.1399
Echinococcus multilocularis thyroid hormone receptor alpha 0.0155 0.1169 0.1399
Loa Loa (eye worm) hypothetical protein 0.0021 0.0079 0.017
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0155 0.1169 0.1399
Trypanosoma brucei unspecified product 0.0041 0.0242 0.0906
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Schistosoma mansoni tar DNA-binding protein 0.0582 0.4626 0.679
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0273 0.0591
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0087 0.0129
Mycobacterium tuberculosis Probable hydrolase 0.0111 0.0811 0.1366
Schistosoma mansoni nuclear receptor 0.0073 0.0504 0.074
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0155 0.1169 0.1399
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0028 0.002
Entamoeba histolytica deoxycytidyl transferase, putative 0.006 0.0392 0.0392
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0295 0.23 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0092 0.0657 0.078
Echinococcus granulosus serotonin receptor 0.0015 0.0028 0.002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0028 0.004
Plasmodium vivax basic transcription factor 3b, putative 0.0181 0.1377 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0097 0.0099
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0392 0.1567
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.23 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0079 0.0547 0.0647
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.006 0.0259
Echinococcus granulosus lipoxygenase domain containing protein 0.0079 0.0547 0.0647
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0021 0.0079 0.0183
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0225 0.0259
Trichomonas vaginalis receptor histidine kinase, putative 0.0021 0.0079 0.0059
Trichomonas vaginalis esterase, putative 0.0111 0.0811 0.0793
Brugia malayi RNA, U transporter 1 0.0084 0.0592 0.1228
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.0306 0.0357
Loa Loa (eye worm) hypothetical protein 0.006 0.0392 0.0848
Trypanosoma cruzi heat shock protein 85, putative 0.0082 0.057 0.2481
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0126 0.0184
Entamoeba histolytica heat shock protein 90, putative 0.0102 0.0739 0.0739
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0235 0.0342
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0097 0.0097
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.015 0.1088
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0155 0.1169 0.2483
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0097 0.0098
Schistosoma mansoni thyroid hormone receptor 0.0155 0.1169 0.1717
Echinococcus multilocularis heat shock protein 0.0102 0.0739 0.088
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1422 0.1405
Plasmodium falciparum thioredoxin reductase 0.0092 0.0653 0.4541
Loa Loa (eye worm) hypothetical protein 0.0028 0.0135 0.0291
Schistosoma mansoni cpg binding protein 0.0065 0.0438 0.0643
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0028 0.002
Mycobacterium tuberculosis Conserved protein 0.0111 0.0811 0.1366
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0021 0.0079 0.0065
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0235 0.0385
Schistosoma mansoni intermediate filament proteins 0.0084 0.0588 0.0864
Plasmodium falciparum basic transcription factor 3b, putative 0.0181 0.1377 1
Schistosoma mansoni zinc finger protein 0.0016 0.0038 0.0055
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0039 0.0034
Mycobacterium tuberculosis Conserved protein 0.0111 0.0811 0.1366
Echinococcus granulosus g protein coupled receptor 0.0015 0.0028 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0811 0.0793
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0225 0.098
Giardia lamblia Heat shock protein HSP 90-alpha 0.0102 0.0739 0.0684
Schistosoma mansoni hypothetical protein 0.0518 0.4108 0.603
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.0028 0.002
Plasmodium falciparum DNA gyrase subunit B 0.0021 0.0079 0.0217
Brugia malayi conserved hypotetical protein 0.0073 0.0504 0.1036
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0028 0.002
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0225 0.098
Echinococcus multilocularis tumor protein p63 0.1035 0.8293 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.0028 0.002
Onchocerca volvulus 0.0111 0.0811 0.2638
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0155 0.1169 0.1717
Loa Loa (eye worm) hypothetical protein 0.0111 0.0811 0.1753
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0898 0.6521
Brugia malayi hypothetical protein 0.0082 0.0575 0.1191
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0608 0.4839 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0073 0.0504 0.0596
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0028 0.004
Onchocerca volvulus 0.0031 0.0164 0.0459
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0212 0.0244
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0028 0.002
Echinococcus granulosus dna polymerase kappa 0.006 0.0392 0.046
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0155 0.1169 0.2483
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0028 0.002
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0087 0.0092
Trypanosoma cruzi ISWI complex protein 0.0016 0.0038 0.0163
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0028 0.002
Schistosoma mansoni opsin-like receptor 0.0015 0.0028 0.004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Loa Loa (eye worm) hypothetical protein 0.0082 0.0575 0.1244
Plasmodium vivax hypothetical protein, conserved 0.0111 0.0811 0.5888
Schistosoma mansoni DNA polymerase eta 0.006 0.0392 0.0576
Brugia malayi hypothetical protein 0.0149 0.1116 0.2368
Treponema pallidum fructose-bisphosphate aldolase 0.1246 1 1
Brugia malayi Importin beta-1 subunit 0.003 0.015 0.0266
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.006 0.0097
Echinococcus granulosus beta LACTamase domain containing family member 0.0111 0.0811 0.0966
Schistosoma mansoni hypothetical protein 0.0015 0.0028 0.004
Trypanosoma brucei heat shock protein, putative 0.0102 0.0739 0.3103
Schistosoma mansoni hypothetical protein 0.0051 0.0321 0.0472
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0167 0.0189
Trypanosoma brucei heat shock protein 90, putative 0.0102 0.0739 0.3103
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0167 0.1215
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0155 0.1169 0.2483
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0021 0.0079 0.0173
Trypanosoma cruzi DNA topoisomerase II, putative 0.0021 0.0079 0.0343
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0697 0.1507
Schistosoma mansoni DNA helicase recq1 0.0022 0.0087 0.0127
Echinococcus multilocularis muscleblind protein 0.0165 0.1243 0.1487
Entamoeba histolytica transcription factor BTF3, putative 0.0181 0.1377 0.1377
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0242 0.0906
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0235 0.102
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Loa Loa (eye worm) hypothetical protein 0.004 0.0237 0.0513
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0155 0.1169 0.2483
Echinococcus granulosus heat shock protein 90 0.0082 0.057 0.0676
Echinococcus multilocularis survival motor neuron protein 1 0.0249 0.1928 0.2314
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0039 0.0034
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0052 0.005
Entamoeba histolytica hypothetical protein 0.0075 0.0516 0.0516
Trypanosoma cruzi heat shock protein 90, putative 0.006 0.04 0.1737
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0237 0.0274
Loa Loa (eye worm) TAR-binding protein 0.0582 0.4626 1
Schistosoma mansoni zinc finger protein 0.0073 0.0504 0.074
Schistosoma mansoni hypothetical protein 0.0015 0.0028 0.004
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0028 0.002
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.0028 0.006
Loa Loa (eye worm) nuclear receptor NHR-67 0.0073 0.0504 0.109
Loa Loa (eye worm) hypothetical protein 0.0073 0.05 0.1081
Brugia malayi TAR-binding protein 0.0582 0.4626 1
Loa Loa (eye worm) hypothetical protein 0.0155 0.1169 0.2528
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0073 0.0504 0.109
Loa Loa (eye worm) hypothetical protein 0.0155 0.1169 0.2528
Loa Loa (eye worm) hypothetical protein 0.0155 0.1169 0.2528
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0021 0.0079 0.0173
Echinococcus multilocularis serotonin receptor 0.0015 0.0028 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0028 0.004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0155 0.1169 0.2528
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.2214 0.2199
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0155 0.1169 0.2483
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0167 0.0574
Trichomonas vaginalis ran, putative 0.0022 0.0086 0.0067
Brugia malayi MH2 domain containing protein 0.0117 0.0855 0.18
Brugia malayi hypothetical protein 0.0079 0.0547 0.1129
Loa Loa (eye worm) hypothetical protein 0.0049 0.0306 0.0662
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0155 0.1169 0.1399
Chlamydia trachomatis DNA gyrase subunit B 0.0021 0.0079 0.2453
Onchocerca volvulus Glucosylceramidase homolog 0.0187 0.1422 0.4695
Echinococcus multilocularis lipoxygenase domain containing protein 0.0079 0.0547 0.0647
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0155 0.1169 0.1399
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0032 0.0167 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.093 0.7446 0.8978
Echinococcus granulosus snurportin 1 0.0316 0.2472 0.2972
Trichomonas vaginalis set domain proteins, putative 0.024 0.1852 0.1835
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 1 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0023 0.0099 0.0155
Echinococcus multilocularis FTZ F1 alpha 0.0155 0.1169 0.1399
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Schistosoma mansoni coup transcription factor 0.0155 0.1169 0.1717
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0087 0.0217
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0097 0.0039
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0082 0.0177
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 1 1
Brugia malayi ecdysone receptor 0.0073 0.0504 0.1036
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0032 0.0167 0.0245
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0155 0.1169 0.1399
Mycobacterium tuberculosis Probable oxidoreductase 0.0233 0.1794 0.3114
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0155 0.1169 0.1717
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0028 0.002
Leishmania major mitochondrial DNA topoisomerase II 0.0021 0.0079 0.0183
Loa Loa (eye worm) heat shock protein 75 0.0042 0.025 0.054
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.0028 0.006
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.006 0.0432
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Onchocerca volvulus 0.0073 0.0504 0.1605
Entamoeba histolytica heat shock protein 90, putative 0.0102 0.0739 0.0739
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.0028 0.002
Echinococcus granulosus sex peptide receptor 0.0015 0.0028 0.002
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.0028 0.002
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0233 0.1794 0.3114
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0082 0.057 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0225 0.0259
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0317 0.0629
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0111 0.0811 0.1753
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0433 0.0433
Loa Loa (eye worm) hypothetical protein 0.0042 0.025 0.054
Schistosoma mansoni opsin-like receptor 0.0015 0.0028 0.004
Schistosoma mansoni lamin 0.0084 0.0588 0.0864
Loa Loa (eye worm) heat shock protein 90 0.0102 0.0739 0.1598
Mycobacterium ulcerans hypothetical protein 0.0018 0.006 0.002
Echinococcus granulosus heat shock protein 90 0.0102 0.0739 0.088
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Brugia malayi hypothetical protein 0.0079 0.0547 0.1129
Brugia malayi beta-lactamase family protein 0.0111 0.0811 0.1704
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0042 0.025 0.025
Schistosoma mansoni endoplasmin 0.0102 0.0739 0.1085
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.1503 0.1486
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0898 0.1072
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0135 0.0978
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.0028 0.006
Trichomonas vaginalis sensor histidine kinase, putative 0.0021 0.0079 0.0059
Mycobacterium ulcerans esterase/lipase LipP 0.0111 0.0811 0.1589
Echinococcus granulosus bloom syndrome protein 0.0022 0.0087 0.0092
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0209 0.1605 0.2778
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0161 0.0348
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0097 0.0152
Loa Loa (eye worm) hypothetical protein 0.0381 0.2997 0.6479
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0284 0.2214 0.4786
Mycobacterium ulcerans hypothetical protein 0.0111 0.0811 0.1589
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0898 0.3805
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0082 0.0575 0.0844
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0306 0.0449
Loa Loa (eye worm) hypothetical protein 0.0023 0.0097 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0392 0.1567
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0392 0.1705
Loa Loa (eye worm) hypothetical protein 0.0155 0.1169 0.2528
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0087 0.0067
Trypanosoma brucei unspecified product 0.0041 0.0242 0.0906
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0392 0.1567
Leishmania major DNA topoisomerase ii 0.0021 0.0079 0.0183
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0028 0.006
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.006 0.0259
Schistosoma mansoni nuclear receptor 0.0073 0.0504 0.074
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0028 0.002
Mycobacterium tuberculosis Conserved protein 0.0021 0.0079 0.0065
Echinococcus multilocularis somatostatin receptor 0.0015 0.0028 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Loa Loa (eye worm) hypothetical protein 0.0165 0.1243 0.2686
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0167 0.0884
Loa Loa (eye worm) hypothetical protein 0.0097 0.0696 0.1505
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0032 0.0167 0.0222
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0052 0.0077
Loa Loa (eye worm) hypothetical protein 0.0108 0.0789 0.1705
Echinococcus multilocularis lamin 0.0084 0.0588 0.0698
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0235 0.0871
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0246 0.1069
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0155 0.1169 0.2483
Schistosoma mansoni nuclear hormone receptor 0.0073 0.0504 0.074
Schistosoma mansoni hypothetical protein 0.0852 0.6813 1
Echinococcus granulosus g-protein coupled receptor 0.0015 0.0028 0.002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1041 0.4526
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Trichomonas vaginalis conserved hypothetical protein 0.0359 0.2818 0.2804
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.002 0.000000000073056
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0246 0.1069
Schistosoma mansoni amine GPCR 0.0015 0.0028 0.004
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0246 0.1069
Onchocerca volvulus 0.0111 0.0811 0.2638
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0028 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0028 0.002
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0073 0.0504 0.0596
Loa Loa (eye worm) hypothetical protein 0.0165 0.1243 0.2686
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0021 0.0079 0.0065
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.006 0.0392 0.046
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0144 0.0161
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.006 0.0259
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0697 0.1023
Echinococcus granulosus g protein coupled receptor 0.0015 0.0028 0.002
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0135 0.0638
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0028 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0028 0.002
Schistosoma mansoni hypothetical protein 0.0518 0.4108 0.603
Mycobacterium tuberculosis Conserved protein 0.0111 0.0811 0.1366
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0392 0.1705
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0021 0.0079 0.0065
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.0947 0.139
Echinococcus multilocularis dna polymerase eta 0.006 0.0392 0.046
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0086 0.0628
Brugia malayi Bromodomain containing protein 0.0039 0.0229 0.0439
Plasmodium vivax SET domain protein, putative 0.0031 0.0164 0.1189
Trypanosoma cruzi heat shock protein 85, putative 0.0102 0.0739 0.3215
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0021 0.0079 0.0082
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0028 0.004
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0433 0.0509
Loa Loa (eye worm) hypothetical protein 0.0249 0.1928 0.4167
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0697 0.0829
Schistosoma mansoni histamine h1 receptor 0.0015 0.0028 0.004
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0021 0.0079 0.0572
Toxoplasma gondii NAC domain-containing protein 0.0181 0.1377 1
Schistosoma mansoni hypothetical protein 0.0079 0.0547 0.0802
Schistosoma mansoni bromodomain containing protein 0.0069 0.0466 0.0683
Onchocerca volvulus 0.0023 0.0097 0.0235
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0225 0.0831
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.0028 0.004
Schistosoma mansoni thyroid hormone receptor 0.0155 0.1169 0.1717
Echinococcus multilocularis geminin 0.0518 0.4108 0.4947
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0082 0.0575 0.1244
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0028 0.004
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0155 0.1169 0.2528
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0161 0.0837
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0235 0.102
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0021 0.0079 0.006
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0032 0.0167 0.0245
Loa Loa (eye worm) hypothetical protein 0.0017 0.005 0.0108
Brugia malayi Steroid receptor seven-up type 2 0.0155 0.1169 0.2483
Brugia malayi Nuclear hormone receptor E75 0.0073 0.0504 0.1036
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.1041 0.4435
Schistosoma mansoni microtubule-associated protein tau 0.0727 0.5798 0.851
Brugia malayi hypothetical protein 0.0075 0.0516 0.1061
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0087 0.0092
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Echinococcus granulosus neuropeptide s receptor 0.0015 0.0028 0.002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0167 0.0728
Mycobacterium ulcerans beta-lactamase 0.0111 0.0811 0.1589
Echinococcus granulosus dna polymerase eta 0.006 0.0392 0.046
Plasmodium vivax endoplasmin, putative 0.0102 0.0739 0.5368
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0164 0.1189
Trypanosoma cruzi trypanothione reductase, putative 0.0092 0.0653 0.2839
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0811 0.0793
Loa Loa (eye worm) hypothetical protein 0.0082 0.0576 0.1245
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0235 0.027
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0086 0.0091
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0235 0.139
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0086 0.0091
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0097 0.0099
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0111 0.0811 0.1704
Loa Loa (eye worm) hypothetical protein 0.0155 0.1169 0.2528
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Schistosoma mansoni cpg binding protein 0.0065 0.0438 0.0643
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0233 0.1794 0.3114
Entamoeba histolytica hypothetical protein 0.0075 0.0516 0.0516
Brugia malayi ecdysteroid receptor 0.0155 0.1169 0.2483
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0021 0.0079 0.0572
Mycobacterium tuberculosis Probable dehydrogenase 0.0209 0.1605 0.2778
Brugia malayi Pre-SET motif family protein 0.0031 0.0164 0.0296
Loa Loa (eye worm) hypothetical protein 0.0079 0.0547 0.1182
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0898 0.1318
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0395 0.0853
Brugia malayi beta-NAC-like protein 0.0181 0.1377 0.2936
Toxoplasma gondii heat shock protein 75, putative 0.0042 0.025 0.1813
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0021 0.0079 0.2453
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0021 0.0079 0.0111
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0898 0.1072
Schistosoma mansoni hypothetical protein 0.005 0.0317 0.0465
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0028 0.002
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0225 0.043
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0155 0.1169 0.1399
Schistosoma mansoni ap endonuclease 0.004 0.0235 0.0344
Loa Loa (eye worm) hypothetical protein 0.0149 0.1116 0.2413
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0135 0.043
Echinococcus multilocularis endoplasmin 0.0082 0.057 0.0676
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 1 1
Brugia malayi CXXC zinc finger family protein 0.006 0.0395 0.0798
Leishmania major GTP-binding protein, putative 0.0022 0.0086 0.0216
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.006 0.0392 0.0848
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0021 0.0079 0.0082
Echinococcus granulosus importin subunit beta 1 0.003 0.015 0.0168
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0104 0.0085
Echinococcus granulosus survival motor neuron protein 1 0.0249 0.1928 0.2314
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.006 0.0432
Trypanosoma cruzi heat shock protein 85, putative 0.0102 0.0739 0.3215
Plasmodium falciparum LCCL domain-containing protein 0.0079 0.0547 0.374
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.006 0.0392 0.0622
Schistosoma mansoni DNA polymerase IV / kappa 0.0018 0.006 0.0087
Echinococcus multilocularis muscleblind protein 1 0.0165 0.1243 0.1487
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0167 0.0884
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0028 0.002
Loa Loa (eye worm) hypothetical protein 0.0151 0.1137 0.2458
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0097 0.0039
Loa Loa (eye worm) hypothetical protein 0.0082 0.0575 0.1244
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0111 0.0811 0.1366
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0028 0.002
Plasmodium vivax heat shock protein 86, putative 0.0102 0.0739 0.5368
Schistosoma mansoni terminal deoxycytidyl transferase 0.006 0.0392 0.0576
Plasmodium falciparum importin beta, putative 0.003 0.015 0.0752
Loa Loa (eye worm) hypothetical protein 0.0017 0.005 0.0108
Echinococcus multilocularis cpg binding protein 0.0065 0.0438 0.0516
Brugia malayi Thioredoxin reductase 0.0092 0.0653 0.136
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0167 0.0148
Echinococcus granulosus lamin dm0 0.0084 0.0588 0.0698
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0021 0.0079 0.0082
Brugia malayi Pre-SET motif family protein 0.0211 0.1617 0.3457
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0028 0.002
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0086 0.0376
Mycobacterium tuberculosis Conserved hypothetical protein 0.006 0.0392 0.0622
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0028 0.002
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1246 1 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.0306 0.0357
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0392 0.1567
Echinococcus granulosus RUN 0.0079 0.0547 0.0647
Plasmodium falciparum glutathione reductase 0.0032 0.0167 0.0884
Echinococcus multilocularis lamin dm0 0.0084 0.0588 0.0698
Trichomonas vaginalis DNA polymerase eta, putative 0.006 0.0392 0.0373
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.015 0.0497
Loa Loa (eye worm) beta-lactamase 0.0111 0.0811 0.1753
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0246 0.0921
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0167 0.0574
Loa Loa (eye worm) hypothetical protein 0.0017 0.005 0.0108
Brugia malayi nuclear hormone receptor 0.0155 0.1169 0.2483
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0028 0.002
Brugia malayi hypothetical protein 0.0073 0.0504 0.1036
Echinococcus granulosus transcription factor btf3 0.0181 0.1377 0.165
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0086 0.0628
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0161 0.0546
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0898 0.1318
Leishmania major developmentally regulated phosphoprotein-like protein 0.0021 0.0079 0.0183
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.0028 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0392 0.1705
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0073 0.0504 0.0596
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.0028 0.004
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0155 0.1169 0.1399
Brugia malayi nuclear receptor NHR-67 0.0073 0.0504 0.1036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0073 0.0504 0.0596
Echinococcus granulosus neuropeptide receptor 0.0015 0.0028 0.002
Echinococcus multilocularis heat shock protein 90 0.0082 0.057 0.0676
Echinococcus multilocularis GPCR, family 2 0.005 0.0317 0.0369
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0433 0.1881
Trypanosoma brucei DNA polymerase eta, putative 0.006 0.0392 0.1567
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.0028 0.002
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0161 0.0182
Loa Loa (eye worm) hypothetical protein 0.0017 0.005 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0225 0.0206
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Loa Loa (eye worm) hypothetical protein 0.0111 0.0811 0.1753
Brugia malayi hypothetical protein 0.0018 0.0055 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0155 0.1169 0.2528
Brugia malayi nuclear hormone receptor family member odr-7 0.0073 0.0504 0.1036
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.0028 0.006
Echinococcus multilocularis zinc finger protein 0.0024 0.0101 0.0109
Echinococcus granulosus g protein coupled receptor 0.0015 0.0028 0.002
Schistosoma mansoni importin beta-1 0.003 0.015 0.022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0028 0.004
Schistosoma mansoni neuropeptide receptor 0.0015 0.0028 0.004
Mycobacterium ulcerans hypothetical protein 0.0155 0.1169 0.2336
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0167 0.0574
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.0028 0.002
Mycobacterium ulcerans DNA gyrase subunit B 0.0021 0.0079 0.006
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.006 0.0097
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.0028 0.002
Plasmodium falciparum thioredoxin reductase 0.0032 0.0167 0.0884
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0155 0.1169 0.1399
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0155 0.1169 0.2528
Echinococcus granulosus ecdysone induced protein 78C 0.0155 0.1169 0.1399
Schistosoma mansoni adenoreceptor 0.0015 0.0028 0.004
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0159 0.1196 0.254
Brugia malayi Endoplasmin precursor 0.0102 0.0739 0.1548
Loa Loa (eye worm) RNA binding protein 0.0582 0.4626 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0092 0.0653 0.1085
Schistosoma mansoni eyes absent homolog 0.0097 0.0696 0.1022
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.1617 0.3496
Schistosoma mansoni neuropeptide receptor 0.0015 0.0028 0.004
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0155 0.1169 0.1717
Schistosoma mansoni DNA topoisomerase II 0.0021 0.0079 0.0116
Plasmodium vivax DNA topoisomerase II, putative 0.0021 0.0079 0.0572
Entamoeba histolytica hypothetical protein 0.0024 0.0104 0.0104
Plasmodium vivax importin-beta 2, putative 0.003 0.015 0.1088
Echinococcus granulosus heat shock protein 0.0102 0.0739 0.088
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1422 0.1405
Trichomonas vaginalis conserved hypothetical protein 0.0181 0.1377 0.136
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Echinococcus granulosus orexin receptor type 2 0.0015 0.0028 0.002
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0021 0.0079 0.0065
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Trypanosoma brucei heat shock protein, putative 0.0102 0.0739 0.3103
Onchocerca volvulus 0.0151 0.1137 0.3736
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0086 0.0275
Brugia malayi steroid hormone receptor 0.0155 0.1169 0.2483
Trichomonas vaginalis DNA topoisomerase II, putative 0.0021 0.0079 0.0059
Schistosoma mansoni tar DNA-binding protein 0.0582 0.4626 0.679
Trichomonas vaginalis heat shock protein, putative 0.0042 0.025 0.0231
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0028 0.002
Loa Loa (eye worm) hypothetical protein 0.0011 0.000000000072912 0.00000000015762
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0073 0.0504 0.1605
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0225 0.0331
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Plasmodium vivax multidomain scavenger receptor, putative 0.0079 0.0547 0.3968
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0021 0.0079 0.0059
Echinococcus multilocularis Polycystic kidney disease protein 0.0079 0.0547 0.0647
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0028 0.002
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0087 0.0092
Brugia malayi Nuclear hormone receptor-like 1 0.0155 0.1169 0.2483
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0811 0.0793
Echinococcus granulosus geminin 0.0518 0.4108 0.4947
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0225 0.0331
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0225 0.0259
Brugia malayi Nuclear hormone receptor-like 1 0.0082 0.0575 0.1191
Brugia malayi nuclear hormone receptor 0.0073 0.0504 0.1036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0155 0.1169 0.2528
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0073 0.0504 0.1605
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0155 0.1169 0.2483
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.0028 0.004
Trypanosoma brucei chrX additional, unordered contigs 0.0018 0.006 0.0097
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0225 0.0259
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.002 0.000000000073056
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0021 0.0079 0.0343
Trichomonas vaginalis heat shock protein, putative 0.0063 0.0419 0.04
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0161 0.117
Schistosoma mansoni hypothetical protein 0.0316 0.2472 0.3628
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0167 0.18
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0392 0.1567
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0082 0.057 0.0939
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0028 0.004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.006 0.0097
Echinococcus multilocularis neuropeptide receptor A26 0.0015 0.0028 0.002
Brugia malayi Probable DNA topoisomerase II 0.0021 0.0079 0.0111
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0167 0.0728
Loa Loa (eye worm) DR-78 0.0073 0.0504 0.109
Loa Loa (eye worm) hypothetical protein 0.0082 0.0575 0.1244
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.0028 0.002
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0317 0.0369
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.0028 0.004
Plasmodium falciparum glutathione reductase 0.0092 0.0653 0.4541
Plasmodium falciparum endoplasmin, putative 0.0063 0.0419 0.2778
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0155 0.1169 0.1399
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0069 0.007
Brugia malayi latrophilin 2 splice variant baaae 0.0108 0.0789 0.1655
Echinococcus granulosus endoplasmin 0.0082 0.057 0.0676
Entamoeba histolytica DNA topoisomerase II, putative 0.0021 0.0079 0.0079
Mycobacterium ulcerans two component sensor kinase MprB 0.0021 0.0079 0.006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0392 0.1567
Echinococcus multilocularis musashi 0.0084 0.0588 0.0698
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0097 0.0099
Toxoplasma gondii ABC1 family protein 0.0111 0.0811 0.5888
Brugia malayi kinase, mitochondrial precursor 0.0021 0.0079 0.0111
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0028 0.004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0155 0.1169 0.2528
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0161 0.0182
Plasmodium falciparum heat shock protein 90, putative 0.0042 0.025 0.1505
Mycobacterium ulcerans two component regulator - sensor kinase 0.0021 0.0079 0.006
Giardia lamblia DINP protein human, muc B family 0.006 0.0392 0.0335
Leishmania major mitochondrial DNA polymerase beta 0.0295 0.23 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0433 0.1881
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0069 0.007
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0028 0.002
Plasmodium falciparum DNA topoisomerase 2 0.0021 0.0079 0.0217
Brugia malayi hypothetical protein 0.0028 0.0135 0.0233
Leishmania major hypothetical protein, conserved 0.0028 0.0135 0.043
Leishmania major hypothetical protein, conserved 0.0111 0.0811 0.3419
Loa Loa (eye worm) hypothetical protein 0.0047 0.0293 0.0634
Trypanosoma brucei hypothetical protein, conserved 0.0111 0.0811 0.3419
Echinococcus multilocularis sex peptide receptor 0.0015 0.0028 0.002
Brugia malayi Doublecortin family protein 0.0079 0.0547 0.1129
Mycobacterium tuberculosis Probable esterase LipL 0.0111 0.0811 0.1366
Schistosoma mansoni amine GPCR 0.0015 0.0028 0.004
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0161 0.0546
Schistosoma mansoni transcription factor LCR-F1 0.0075 0.0516 0.0757
Brugia malayi nuclear receptor NHR-88 0.0155 0.1169 0.2483
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0021 0.0079 0.006
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.0028 0.004
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0028 0.004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Schistosoma mansoni DNA helicase recq5 0.0022 0.0087 0.0127
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.0028 0.002
Brugia malayi Latrophilin receptor protein 2 0.005 0.0317 0.0629
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0126 0.0139
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.005 0.0014
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0021 0.0079 0.0065
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0235 0.3168
Brugia malayi beta-lactamase 0.0111 0.0811 0.1704
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0086 0.0187
Brugia malayi intermediate filament protein 0.0084 0.0588 0.122
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.23 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.002 0.000000000073056
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0235 0.1703
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.021 0.024
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.006 0.0392 0.046
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.0028 0.004
Trypanosoma brucei heat shock protein 84, putative 0.0042 0.025 0.0938
Trypanosoma brucei Heat shock protein 83, putative 0.0102 0.0739 0.3103
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.006 0.0392 0.1567
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0167 0.1215
Echinococcus multilocularis beta LACTamase domain containing family member 0.0111 0.0811 0.0966
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0028 0.002
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0023 0.0099 0.0155
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Echinococcus granulosus GPCR family 2 0.005 0.0317 0.0369
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 1 1
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0042 0.025 0.0289
Brugia malayi hypothetical protein 0.0381 0.2997 0.6458
Brugia malayi Nuclear hormone receptor-like 1 0.0082 0.0575 0.1191
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0087 0.0027
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0898 0.1771
Toxoplasma gondii heat shock protein HSP90 0.0102 0.0739 0.5368
Schistosoma mansoni hypothetical protein 0.0015 0.0028 0.004
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.006 0.0392 0.0576
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0087 0.0276
Echinococcus granulosus zinc finger protein 0.0024 0.0101 0.0109
Mycobacterium ulcerans hypothetical protein 0.0023 0.0097 0.0099
Echinococcus multilocularis orexin receptor type 2 0.0015 0.0028 0.002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0697 0.0829
Schistosoma mansoni biogenic amine receptor 0.0015 0.0028 0.004
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0235 0.0176
Schistosoma mansoni RAR-like nuclear receptor 0.0155 0.1169 0.1717
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0079 0.0572
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0898 0.1771
Leishmania major DNA polymerase eta, putative 0.006 0.0392 0.1567
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0225 0.0259
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.0028 0.002
Onchocerca volvulus Protein ultraspiracle homolog 0.0155 0.1169 0.3846
Brugia malayi RNA binding protein 0.0582 0.4626 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0079 0.0547 0.0647
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0087 0.0092
Plasmodium vivax thioredoxin reductase, putative 0.0092 0.0653 0.474
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0392 0.0793
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0028 0.002
Echinococcus granulosus cpg binding protein 0.0065 0.0438 0.0516
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.0028 0.004
Leishmania major DNA polymerase kappa, putative 0.0018 0.006 0.0097
Loa Loa (eye worm) hypothetical protein 0.0021 0.0079 0.017
Schistosoma mansoni opsin-like receptor 0.0015 0.0028 0.004
Loa Loa (eye worm) doublecortin family protein 0.0079 0.0547 0.1182
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0028 0.004
Loa Loa (eye worm) histone methyltransferase 0.002 0.0069 0.0149
Trypanosoma brucei developmentally regulated phosphoprotein 0.0021 0.0079 0.0183
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0021 0.0079 0.0065
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.0028 0.004
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0021 0.0079 0.006
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0028 0.002
Trypanosoma cruzi transcription factor btf3, putative 0.0181 0.1377 0.599
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0155 0.1169 0.2483
Loa Loa (eye worm) hypothetical protein 0.0155 0.1169 0.2528
Schistosoma mansoni heat shock protein 0.0102 0.0739 0.1085
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.0028 0.002
Schistosoma mansoni loxhd1 0.0079 0.0547 0.0802
Plasmodium falciparum DNA repair protein REV1, putative 0.0018 0.006 0.0072
Schistosoma mansoni retinoic acid receptor RXR 0.0155 0.1169 0.1717
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0028 0.002
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0235 0.0235
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0392 0.1567
Trypanosoma brucei heat shock protein, putative 0.0102 0.0739 0.3103
Echinococcus granulosus Nuclear hormone receptor HR96 0.0073 0.0504 0.0596
Schistosoma mansoni hypothetical protein 0.0108 0.0789 0.1158
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0087 0.0067
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0039 0.0034
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.0028 0.004
Schistosoma mansoni ran 0.0022 0.0086 0.0127
Onchocerca volvulus Huntingtin homolog 0.0381 0.2997 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0111 0.0811 0.1366
Loa Loa (eye worm) hypothetical protein 0.0381 0.2997 0.6479
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0097 0.0099
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0233 0.1794 0.3603
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0028 0.002
Trypanosoma brucei DNA topoisomerase ii 0.0021 0.0079 0.0183
Plasmodium vivax DNA gyrase subunit B, putative 0.0021 0.0079 0.0572
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0073 0.0504 0.074
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.002 0.000000000073056
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0225 0.0259
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0317 0.0369
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0161 0.0182
Trypanosoma cruzi heat shock protein 85, putative 0.0102 0.0739 0.3215
Schistosoma mansoni transcription factor btf3 0.0181 0.1377 0.2022
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Echinococcus granulosus fmrfamide receptor 0.0015 0.0028 0.002
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0392 0.0714
Plasmodium falciparum heat shock protein 90, putative 0.0042 0.025 0.1505
Schistosoma mansoni hypothetical protein 0.0016 0.0038 0.0055
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0028 0.004
Schistosoma mansoni polycystin 1-related 0.0079 0.0547 0.0802
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0155 0.1169 0.2483
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0028 0.004
Echinococcus multilocularis neuropeptide s receptor 0.0015 0.0028 0.002
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0697 0.1456
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0087 0.0087
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0097 0.0265
Loa Loa (eye worm) hypothetical protein 0.0097 0.0696 0.1505
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0811 0.3527
Loa Loa (eye worm) hypothetical protein 0.0022 0.0087 0.0187
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0164 0.0185
Mycobacterium leprae conserved hypothetical protein 0.0111 0.0811 0.1538
Toxoplasma gondii heat shock protein 90, putative 0.0102 0.0739 0.5368
Echinococcus multilocularis ecdysone induced protein 78C 0.0155 0.1169 0.1399
Onchocerca volvulus 0.0149 0.1116 0.3667
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Mycobacterium ulcerans heat shock protein 90 0.0082 0.057 0.1087
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0021 0.0079 0.0065
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0086 0.0128
Loa Loa (eye worm) hypothetical protein 0.0017 0.005 0.0108
Echinococcus granulosus neuropeptide receptor A26 0.0015 0.0028 0.002
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0021 0.0079 0.0173
Schistosoma mansoni ran 0.0022 0.0086 0.0127
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0028 0.006
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.0028 0.002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0857 0.6221
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0284 0.2214 0.4755
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0321 0.0639
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0097 0.0099
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0021 0.0079 0.0572
Echinococcus granulosus intermediate filament protein 0.0084 0.0588 0.0698
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0073 0.0504 0.074
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0021 0.0079 0.0065
Loa Loa (eye worm) endoplasmin 0.0102 0.0739 0.1598
Echinococcus granulosus muscleblind protein 0.0165 0.1243 0.1487
Leishmania major heat shock protein 83-1 0.0102 0.0739 0.3103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.002 0.000000000073056
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0155 0.1169 0.1399
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0161 0.0237
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0811 0.0793
Mycobacterium leprae Probable lipase LipE 0.0111 0.0811 0.1538
Loa Loa (eye worm) hypothetical protein 0.0023 0.0097 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0242 0.0906
Schistosoma mansoni tar DNA-binding protein 0.0582 0.4626 0.679
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0097 0.0097
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0073 0.0504 0.0596
Onchocerca volvulus 0.0079 0.0547 0.1748
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0135 0.0586
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Loa Loa (eye worm) intermediate filament protein 0.0084 0.0588 0.1272
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0317 0.0369
Trichomonas vaginalis conserved hypothetical protein 0.0181 0.1377 0.136
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0164 0.024
Echinococcus multilocularis transcription factor btf3 0.0181 0.1377 0.165
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Loa Loa (eye worm) steroid hormone receptor 0.0155 0.1169 0.2528
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0855 0.1849
Schistosoma mansoni hypothetical protein 0.0021 0.0082 0.012
Mycobacterium tuberculosis Probable lipase LipD 0.0111 0.0811 0.1366
Loa Loa (eye worm) hypothetical protein 0.0111 0.0811 0.1753
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0082 0.057 0.1033
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1422 0.1405
Brugia malayi Hsp90 protein 0.0042 0.025 0.0483
Trichomonas vaginalis heat shock protein, putative 0.0082 0.057 0.0552
Echinococcus multilocularis heat shock protein 90 0.0102 0.0739 0.088
Giardia lamblia Fructose-bisphosphate aldolase 0.1246 1 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0135 0.0978
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.006 0.0097
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.0028 0.004
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.0129
Giardia lamblia Grp94/Hsp90 0.0082 0.057 0.0514
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0392 0.1567
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0209 0.1605 0.2778
Onchocerca volvulus 0.0111 0.0811 0.2638
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0021 0.0079 0.006
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0209 0.1605 0.2778
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0087 0.0067
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0021 0.0079 0.006
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0087 0.0217
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0392 0.0793
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0021 0.0079 0.0065
Toxoplasma gondii exonuclease III APE 0.004 0.0235 0.1703
Brugia malayi nuclear receptor NHR-88 0.0073 0.0504 0.1036
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0161 0.0701
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0028 0.004
Schistosoma mansoni biogenic amine receptor 0.0015 0.0028 0.004
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0135 0.0586
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0235 0.0871
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.0028 0.002
Echinococcus multilocularis importin subunit beta 1 0.003 0.015 0.0168
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0167 0.18
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.0028 0.006
Loa Loa (eye worm) hypothetical protein 0.003 0.015 0.0324
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0126 0.0139
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0608 0.4839 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0073 0.0504 0.0596
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.021 0.024
Mycobacterium tuberculosis Probable reductase 0.0209 0.1605 0.2778
Schistosoma mansoni cellular tumor antigen P53 0.0151 0.1137 0.1669
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0433 0.1747
Brugia malayi Bromodomain containing protein 0.0081 0.0563 0.1165
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0161 0.0182
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0855 0.1849
Trypanosoma cruzi heat shock protein 90, putative 0.0102 0.0739 0.3215
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0073 0.0504 0.0596
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1422 0.1405
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0021 0.0079 0.0183
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0021 0.0079 0.0343
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0028 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.2214 0.2199
Echinococcus granulosus allatostatin A receptor 0.0015 0.0028 0.002
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0021 0.0079 0.0111
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0039 0.0034
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0392 0.1705
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0075 0.0516 0.061
Echinococcus granulosus somatostatin receptor 0.0015 0.0028 0.002
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.0028 0.002
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0097 0.0152
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0015 0.0028 0.006
Leishmania major heat shock protein, putative 0.0042 0.025 0.0938
Loa Loa (eye worm) hypothetical protein 0.0159 0.1196 0.2585
Schistosoma mansoni hypothetical protein 0.0012 0.0011 0.0016
Loa Loa (eye worm) hypothetical protein 0.0082 0.0575 0.1244
Schistosoma mansoni rab6-interacting 0.0079 0.0547 0.0802
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0028 0.002
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0021 0.0079 0.006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0212 0.0244
Onchocerca volvulus 0.0084 0.0588 0.1889
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0021 0.0079 0.0183
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1422 0.1405
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.002 0.000000000073056
Onchocerca volvulus 0.024 0.1852 0.6143
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0697 0.1023
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0209 0.1605 0.2778
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0155 0.1169 0.1717
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.006 0.0432
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0319 0.1389
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0898 0.1771
Mycobacterium ulcerans putative regultory protein 0.0021 0.0079 0.006
Schistosoma mansoni lipoxygenase 0.014 0.1043 0.1531
Mycobacterium ulcerans lipase LipD 0.0111 0.0811 0.1589
Onchocerca volvulus Huntingtin homolog 0.0381 0.2997 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0097 0.0265
Leishmania major DNA damage repair protein, putative 0.0018 0.006 0.0097
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0028 0.002
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0097 0.0097
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0225 0.0831
Schistosoma mansoni pyruvate dehydrogenase 0.0021 0.0079 0.0116
Brugia malayi RNA recognition motif domain containing protein 0.0582 0.4626 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0898 0.1522
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0087 0.0629
Trypanosoma cruzi DNA polymerase eta, putative 0.0018 0.006 0.0259
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1422 0.1405
Loa Loa (eye worm) TOPoisomerase family member 0.0021 0.0079 0.017
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0082 0.0575 0.0682
Entamoeba histolytica hypothetical protein 0.0075 0.0516 0.0516
Echinococcus multilocularis allatostatin A receptor 0.0015 0.0028 0.002
Loa Loa (eye worm) nuclear hormone receptor 0.0073 0.0504 0.109
Trypanosoma brucei transcription factor BTF3, putative 0.0181 0.1377 0.5923
Schistosoma mansoni ap endonuclease 0.004 0.0235 0.0344
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Echinococcus granulosus FTZ F1 alpha 0.0155 0.1169 0.1399
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0155 0.1169 0.1717
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0028 0.002
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0104 0.0085
Schistosoma mansoni myosin xvIII 0.0015 0.0028 0.004
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0028 0.006
Onchocerca volvulus 0.0079 0.0547 0.1748
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 1 1
Schistosoma mansoni heat shock protein 0.0102 0.0739 0.1085
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.0028 0.002
Echinococcus multilocularis tar DNA binding protein 0.0582 0.4626 0.5572
Leishmania major trypanothione reductase 0.0092 0.0653 0.272
Brugia malayi Intermediate filament tail domain containing protein 0.0084 0.0588 0.122
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0167 0.0728
Brugia malayi nuclear receptor RXR 0.0082 0.0575 0.1191
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.0028 0.002
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0028 0.002
Trypanosoma brucei heat shock protein, putative 0.0102 0.0739 0.3103
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0104 0.0454
Toxoplasma gondii Hsp90 domain-containing protein 0.0042 0.025 0.1813
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0073 0.0504 0.0596
Trypanosoma cruzi DNA topoisomerase II, putative 0.0021 0.0079 0.0343
Loa Loa (eye worm) hypothetical protein 0.0155 0.1169 0.2528
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0083 0.012
Schistosoma mansoni hypothetical protein 0.005 0.0317 0.0465
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.0028 0.002
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0135 0.0638
Brugia malayi hypothetical protein 0.0073 0.0504 0.1036
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0082 0.057 0.2356
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0811 0.119
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.2214 0.2199
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0028 0.002
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0021 0.0079 0.0082
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0433 0.0509
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Brugia malayi Muscleblind-like protein 0.0165 0.1243 0.2642
Schistosoma mansoni steroid hormone receptor ad4bp 0.0155 0.1169 0.1717
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0155 0.1169 0.3846
Plasmodium vivax glutathione reductase, putative 0.0092 0.0653 0.474
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0167 0.0728
Schistosoma mansoni nuclear hormone receptor 0.0073 0.0504 0.074
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.005 0.0363
Schistosoma mansoni amine GPCR 0.0015 0.0028 0.004
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.1503 0.1486
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0433 0.0881
Toxoplasma gondii hypothetical protein 0.0048 0.0295 0.2144
Schistosoma mansoni amine GPCR 0.0015 0.0028 0.004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Brugia malayi hypothetical protein 0.0249 0.1928 0.4132
Loa Loa (eye worm) hypothetical protein 0.0021 0.0079 0.017
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0021 0.0079 0.0059
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0811 0.119
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0042 0.025 0.0289
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0021 0.0079 0.0079
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0392 0.0714
Echinococcus granulosus dnaJ subfamily B 0.0852 0.6813 0.8213
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0021 0.0079 0.0082
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0235 0.045
Plasmodium vivax DNA repair protein REV1, putative 0.0018 0.006 0.0432
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0392 0.1705
Echinococcus granulosus tumor protein p63 0.1035 0.8293 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0039 0.0058
Trypanosoma brucei trypanothione reductase 0.0092 0.0653 0.272
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0392 0.1567
Trypanosoma brucei unspecified product 0.006 0.0392 0.1567
Loa Loa (eye worm) glutathione reductase 0.0092 0.0653 0.1411
Loa Loa (eye worm) hypothetical protein 0.0111 0.0811 0.1753
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0021 0.0079 0.0059
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0028 0.004
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0167 0.0574
Brugia malayi isocitrate dehydrogenase 0.0031 0.0161 0.029
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0209 0.1605 0.3206
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.0028 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0225 0.0206
Trichomonas vaginalis heat shock protein, putative 0.0102 0.0739 0.0721
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.0028 0.002
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0057 0.0124
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0028 0.004
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0235 0.0235
Echinococcus multilocularis snurportin 1 0.0316 0.2472 0.2972
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0436 0.0513
Schistosoma mansoni zinc finger protein 0.0024 0.0101 0.0148
Leishmania major DNA polymerase eta, putative 0.0018 0.006 0.0097
Loa Loa (eye worm) ICD-1 protein 0.0181 0.1377 0.2978
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0167 0.0574
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0225 0.0206
Brugia malayi Calcitonin receptor-like protein seb-1 0.0159 0.1196 0.254
Echinococcus multilocularis serotonin receptor 0.0015 0.0028 0.002
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0021 0.0079 0.0079
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0167 0.0246
Schistosoma mansoni hypothetical protein 0.0075 0.0516 0.0757
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0032 0.0167 0.0245
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0086 0.0027
Brugia malayi nuclear receptor RXR 0.0073 0.0504 0.1036
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.0028 0.002
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0052 0.005
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0281 0.2189 0.2631
Schistosoma mansoni lamin 0.0084 0.0588 0.0864
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.006 0.0259
Brugia malayi hypothetical protein 0.0082 0.0575 0.1191
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0028 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0608 0.4839 0.8528
Loa Loa (eye worm) hypothetical protein 0.0039 0.0225 0.0486
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0028 0.002
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0097 0.0098
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0392 0.1567
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0167 0.0728
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0225 0.0167
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0097 0.0265
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.0028 0.002
Loa Loa (eye worm) hypothetical protein 0.0082 0.0575 0.1244
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0097 0.0099
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0086 0.0216
Loa Loa (eye worm) hypothetical protein 0.0023 0.0097 0.0211
Loa Loa (eye worm) hypothetical protein 0.005 0.0317 0.0685
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0392 0.1567
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0161 0.117
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0021 0.0079 0.0217
Giardia lamblia Heat shock protein HSP 90-alpha 0.0082 0.057 0.0514
Entamoeba histolytica Ran family GTPase 0.0022 0.0086 0.0086
Echinococcus multilocularis dnaJ subfamily B 0.0852 0.6813 0.8213
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0087 0.0129
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0235 0.0215
Brugia malayi glutathione reductase 0.0092 0.0653 0.136
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0087 0.0276
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0369 0.29 0.6246
Schistosoma mansoni lipoxygenase 0.0281 0.2189 0.3214
Onchocerca volvulus 0.0084 0.0588 0.1889
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0235 0.0215
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0028 0.004
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1041 0.4435
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1422 0.1405
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.002 0.000000000073056
Loa Loa (eye worm) hypothetical protein 0.0073 0.0504 0.109
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0021 0.0079 0.0059
Trichomonas vaginalis heat shock protein, putative 0.0082 0.057 0.0552
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0392 0.1567
Brugia malayi tailless protein 0.0073 0.0504 0.1036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.006
Echinococcus granulosus lamin 0.0084 0.0588 0.0698
Echinococcus granulosus neuropeptide receptor 0.0015 0.0028 0.002
Loa Loa (eye worm) hypothetical protein 0.0079 0.0547 0.1182

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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