Detailed information for compound 542532

Basic information

Technical information
  • TDR Targets ID: 542532
  • Name: 1-[2,4,6-trihydroxy-3-[7-hydroxy-2-(4-hydroxy phenyl)chroman-4-yl]phenyl]dodecan-1-one
  • MW: 548.666 | Formula: C33H40O7
  • H donors: 5 H acceptors: 6 LogP: 8.89 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCCCCCCCCC(=O)c1c(O)cc(c(c1O)C1CC(Oc2c1ccc(c2)O)c1ccc(cc1)O)O
  • InChi: 1S/C33H40O7/c1-2-3-4-5-6-7-8-9-10-11-26(36)32-28(38)20-27(37)31(33(32)39)25-19-29(21-12-14-22(34)15-13-21)40-30-18-23(35)16-17-24(25)30/h12-18,20,25,29,34-35,37-39H,2-11,19H2,1H3
  • InChiKey: JGXZVDAPLSTBGZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[2,4,6-trihydroxy-3-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-yl]phenyl]-1-dodecanone
  • 1-[2,4,6-trihydroxy-3-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]phenyl]dodecan-1-one
  • YM 26567-1
  • myristinin A
  • 1-[2,4,6-trihydroxy-3-[7-hydroxy-2-(4-hydroxyphenyl)-4-chromanyl]phenyl]dodecan-1-one
  • 137130-31-5
  • YM-26567-1
  • (+)-trans-4-(3-Dodecanoyl-2,4,6-trihydroxyphenyl)-7-hydroxy-2-(4-hydroxyphenyl)chroman
  • 1-(3-(3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl)-2,4,6-trihydroxyphenyl)-1-dodecanone
  • 1-Dodecanone, 1-(3-(3,4-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl)-2,4,6-trihydroxyphenyl)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0056 0.0115 0.0186
Leishmania major beta tubulin 0.016 0.0422 0.1546
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.009 0.0217 0.1448
Leishmania major beta tubulin 0.016 0.0422 0.1546
Trypanosoma brucei hypothetical protein, conserved 0.007 0.0158 0.0573
Echinococcus multilocularis neuropeptides capa receptor 0.0274 0.0757 0.0754
Echinococcus multilocularis Niemann Pick C1 protein 0.0289 0.0802 0.0799
Leishmania major hypothetical protein, conserved 0.0025 0.0024 0.0078
Toxoplasma gondii ribosomal RNA methyltransferase (FtsJ) family protein 0.0025 0.0025 0.0081
Echinococcus granulosus rrna methyltransferase 3 0.0025 0.0025 0.0022
Toxoplasma gondii SPRY domain-containing protein 0.004 0.0068 0.024
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0034 0.0052 0.0181
Toxoplasma gondii microneme protein MIC4 0.0029 0.0036 0.0123
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0058 0.0122 0.0438
Echinococcus granulosus neuropeptide s receptor 0.0274 0.0757 0.0754
Echinococcus multilocularis beta tubulin 0.016 0.0422 0.0419
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.0099
Onchocerca volvulus 0.0056 0.0115 0.0862
Brugia malayi jmjC domain containing protein 0.0031 0.0043 0.0057
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.009 0.0217 0.0789
Brugia malayi Matrixin family protein 0.0108 0.0269 0.0388
Brugia malayi Trypsin family protein 0.0056 0.0115 0.0163
Echinococcus multilocularis rrna methyltransferase 3 0.0025 0.0025 0.0022
Trichomonas vaginalis WD repeat domain, putative 0.007 0.0157 0.0465
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0024 0.0078
Plasmodium vivax JmjC domain containing protein 0.0031 0.0043 0.0157
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0274 0.0757 0.1098
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Schistosoma mansoni hypothetical protein 0.0031 0.0042 0.0065
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.0517 0.3884
Trypanosoma cruzi cyclin, putative 0.0151 0.0397 0.1453
Echinococcus multilocularis neuropeptide receptor A26 0.0274 0.0757 0.0754
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1139 0.3305 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0274 0.0757 0.1248
Schistosoma mansoni tubulin subunit beta 0.016 0.0422 0.0693
Brugia malayi ubiquitin C-terminal hydrolase UCH-L5 0.0308 0.0857 0.1243
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0274 0.0757 0.1098
Plasmodium vivax subtilisin-like protease 1 0.009 0.0217 0.0799
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Onchocerca volvulus 0.0056 0.0115 0.0862
Echinococcus granulosus Protein patched homolog 1 0.0124 0.0317 0.0314
Toxoplasma gondii subtilisin SUB1 0.009 0.0217 0.0789
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.009 0.0217 0.0354
Brugia malayi hypothetical protein 0.0274 0.0757 0.1098
Echinococcus granulosus cyclin B 0.0151 0.0397 0.0394
Loa Loa (eye worm) hypothetical protein 0.007 0.0158 0.0226
Brugia malayi Probable ClpP-like protease 0.0077 0.018 0.0257
Plasmodium falciparum ribosomal RNA methyltransferase, putative 0.0025 0.0025 0.008
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0088 0.0209 0.0206
Trichomonas vaginalis cyclins, putative 0.0151 0.0397 0.1192
Trypanosoma cruzi CYC2-like cyclin, putative 0.0151 0.0397 0.1453
Schistosoma mansoni hypothetical protein 0.012 0.0304 0.0497
Trichomonas vaginalis cyclin B, putative 0.0063 0.0137 0.0406
Echinococcus granulosus rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Leishmania major subtilisin-like serine peptidase 0.009 0.0217 0.0789
Onchocerca volvulus Putative ribosomal RNA methyltransferase 0.0025 0.0025 0.0168
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.0158 0.0973
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0274 0.0757 0.0754
Toxoplasma gondii hypothetical protein 0.0029 0.0036 0.0123
Echinococcus multilocularis Tubulin beta 2C chain 0.016 0.0422 0.0419
Onchocerca volvulus 0.0274 0.0757 0.5808
Brugia malayi AKH receptor 0.0274 0.0757 0.1098
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0274 0.0757 0.1248
Entamoeba histolytica tubulin family protein 0.016 0.0422 0.4905
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0024 0.0078
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.0158 0.0226
Brugia malayi hypothetical protein 0.0071 0.016 0.0229
Onchocerca volvulus 0.0274 0.0757 0.5808
Onchocerca volvulus 0.0034 0.0052 0.0377
Echinococcus granulosus rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0938 0.2711 1
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0088 0.0209 0.03
Leishmania major beta tubulin 0.016 0.0422 0.1546
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0042 0.0039
Mycobacterium tuberculosis Conserved protein 0.007 0.0158 0.0973
Echinococcus multilocularis musashi 0.0026 0.0029 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.017 0.0506
Schistosoma mansoni hypothetical protein 0.0031 0.0042 0.0065
Loa Loa (eye worm) hypothetical protein 0.0026 0.0027 0.0035
Onchocerca volvulus 0.0274 0.0757 0.5808
Schistosoma mansoni biogenic amine (5HT) receptor 0.0274 0.0757 0.1248
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0274 0.0757 0.0754
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0054 0.0112 0.0597
Entamoeba histolytica hypothetical protein 0.0308 0.0857 1
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0088 0.0209 0.0761
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0008 0.0008
Leishmania major beta tubulin 0.016 0.0422 0.1546
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0274 0.0757 0.0754
Echinococcus multilocularis sex peptide receptor 0.0274 0.0757 0.0754
Echinococcus multilocularis Niemann Pick C1 protein 0.0413 0.1167 0.1164
Toxoplasma gondii ABC1 family protein 0.007 0.0158 0.0573
Echinococcus granulosus Niemann Pick C1 protein 0.0413 0.1167 0.1164
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0115 0.0186
Toxoplasma gondii patched family protein 0.0018 0.0003 0.0001
Giardia lamblia Hypothetical protein 0.0063 0.0137 0.0729
Echinococcus multilocularis neuroendocrine convertase 2 0.1348 0.392 0.3918
Schistosoma mansoni hypothetical protein 0.012 0.0304 0.0497
Entamoeba histolytica cell division protein kinase 2, putative 0.0088 0.0209 0.2416
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0034 0.0052 0.0113
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Schistosoma mansoni site-1 peptidase (S08 family) 0.009 0.0217 0.0354
Loa Loa (eye worm) hypothetical protein 0.0289 0.0802 0.1163
Echinococcus granulosus laminin 0.0041 0.0071 0.0068
Schistosoma mansoni neuropeptide F-like receptor 0.0274 0.0757 0.1248
Onchocerca volvulus 0.041 0.1159 0.8902
Plasmodium falciparum JmjC domain-containing protein, putative 0.0031 0.0043 0.0145
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0082 0.0193 0.1259
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Toxoplasma gondii subtilisin SUB4 0.009 0.0217 0.0789
Plasmodium falciparum deubiquinating/deneddylating enzyme 0.0308 0.0857 0.3152
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0034 0.0052 0.0071
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.018 0.2739
Schistosoma mansoni biogenic amine receptor 0.0274 0.0757 0.1248
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0052 0.0113
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0034 0.0052 0.0113
Echinococcus granulosus tm gpcr rhodopsin 0.0274 0.0757 0.0754
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0034 0.0052 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0209 0.0341
Loa Loa (eye worm) hypothetical protein 0.0029 0.0036 0.0049
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.0158 0.0973
Echinococcus granulosus epidermal growth factor receptor 0.0126 0.0323 0.032
Onchocerca volvulus 0.007 0.0158 0.1194
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0058 0.0122 0.0196
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.018 0.0651
Mycobacterium ulcerans hypothetical protein 0.0056 0.0115 0.1356
Trichomonas vaginalis cyclin B, putative 0.0151 0.0397 0.1192
Brugia malayi putative neuropeptide receptor 0.0274 0.0757 0.1098
Onchocerca volvulus 0.0274 0.0757 0.5808
Brugia malayi beta-tubulin, identical 0.016 0.0422 0.061
Echinococcus multilocularis neuropeptide FF receptor 2 0.2351 0.6872 0.6871
Onchocerca volvulus 0.0029 0.0036 0.0256
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0115 0.0186
Echinococcus granulosus G protein coupled receptor 139 0.0274 0.0757 0.0754
Echinococcus multilocularis cyclin B 0.0151 0.0397 0.0394
Trichomonas vaginalis tubulin beta chain, putative 0.016 0.0422 0.1268
Brugia malayi Dopamine receptor protein 1 0.0274 0.0757 0.1098
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0041 0.0071 0.0099
Trichomonas vaginalis cyclins, putative 0.0151 0.0397 0.1192
Onchocerca volvulus 0.0274 0.0757 0.5808
Echinococcus multilocularis membrane bound transcription factor site 1 0.009 0.0217 0.0214
Schistosoma mansoni patched 1 0.0124 0.0317 0.0519
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0274 0.0757 0.1248
Trichomonas vaginalis cyclin B, putative 0.0151 0.0397 0.1192
Schistosoma mansoni tubulin subunit beta 0.016 0.0422 0.0693
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0116 0.0294 0.5199
Loa Loa (eye worm) oxidoreductase 0.0034 0.0052 0.0071
Onchocerca volvulus 0.0034 0.0052 0.0377
Onchocerca volvulus 0.0034 0.0052 0.0377
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.1139 0.3305 0.3303
Echinococcus granulosus hypothetical protein 0.0274 0.0757 0.0754
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.0158 0.2281
Echinococcus granulosus lamin dm0 0.0026 0.0029 0.0026
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0115 0.0186
Brugia malayi Calcium binding EGF domain containing protein 0.0041 0.0071 0.0099
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Loa Loa (eye worm) hypothetical protein 0.007 0.0158 0.0226
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0034 0.0052 0.0113
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0274 0.0757 0.1098
Echinococcus multilocularis expressed conserved protein 0.0271 0.0751 0.0748
Loa Loa (eye worm) hypothetical protein 0.0077 0.018 0.0257
Onchocerca volvulus Neuropeptide F receptor homolog 0.0274 0.0757 0.5808
Brugia malayi Trypsin family protein 0.041 0.1159 0.1683
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0274 0.0757 0.1248
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0068 0.0197
Loa Loa (eye worm) jmjC domain-containing protein 0.0116 0.0293 0.0421
Schistosoma mansoni jumonji/arid domain-containing protein 0.0116 0.0293 0.0479
Echinococcus multilocularis glycoprotein Antigen 5 0.0056 0.0115 0.0112
Echinococcus granulosus Furin 1 0.0522 0.1487 0.1485
Echinococcus multilocularis cyclins 0.0063 0.0137 0.0134
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0082 0.0193 0.1259
Echinococcus multilocularis dnaJ subfamily B 0.2071 0.6047 0.6045
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0274 0.0757 0.0754
Mycobacterium tuberculosis Conserved protein 0.007 0.0158 0.0973
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0034 0.0052 0.0181
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Loa Loa (eye worm) neuropeptide F receptor 0.0274 0.0757 0.1098
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0274 0.0757 0.1248
Echinococcus granulosus cyclin B3 1 0.0063 0.0137 0.0134
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0115 0.0186
Loa Loa (eye worm) runx1 0.0054 0.011 0.0156
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0034 0.0052 0.0113
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.018 0.5663
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0103 0.0367
Mycobacterium ulcerans hypothetical protein 0.007 0.0158 0.2281
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0037
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0041 0.0071 0.0099
Echinococcus granulosus cyclin dependent kinase 0.0088 0.0209 0.0206
Brugia malayi neuropeptide F receptor 0.0274 0.0757 0.1098
Loa Loa (eye worm) G-protein coupled receptor 0.0274 0.0757 0.1098
Giardia lamblia Beta tubulin 0.016 0.0422 0.2279
Brugia malayi Serotonin receptor 0.0274 0.0757 0.1098
Onchocerca volvulus 0.0029 0.0036 0.0256
Onchocerca volvulus 0.0024 0.0023 0.0149
Echinococcus multilocularis epidermal growth factor receptor 0.0126 0.0323 0.032
Schistosoma mansoni amine GPCR 0.0274 0.0757 0.1248
Echinococcus granulosus peptide allatostatin:somatostatin 0.0274 0.0757 0.0754
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Echinococcus granulosus JmjC domain containing protein 4 0.0031 0.0043 0.0039
Loa Loa (eye worm) hypothetical protein 0.007 0.0158 0.0226
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase BAP1 0.0308 0.0857 0.0854
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0116 0.0294 0.5199
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0088 0.0209 0.0761
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0938 0.2711 0.2709
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0308 0.0857 0.3152
Mycobacterium ulcerans hypothetical protein 0.0192 0.0517 1
Entamoeba histolytica hypothetical protein 0.0024 0.0022 0.0225
Trichomonas vaginalis conserved hypothetical protein 0.0408 0.1151 0.3477
Trichomonas vaginalis conserved hypothetical protein 0.0408 0.1151 0.3477
Brugia malayi jmjC domain containing protein 0.0031 0.0043 0.0057
Brugia malayi endoprotease bli-4 precursor 0.1966 0.5738 0.8349
Brugia malayi PAN domain containing protein 0.0029 0.0036 0.0049
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0058 0.0122 0.0196
Echinococcus granulosus tubulin subunit beta 0.016 0.0422 0.0419
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0043 0.0039
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0058 0.0122 0.0119
Loa Loa (eye worm) matrixin family protein 0.0108 0.0269 0.0388
Brugia malayi Cyclin, N-terminal domain containing protein 0.0063 0.0137 0.0195
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Trypanosoma brucei beta tubulin 0.016 0.0422 0.1546
Trypanosoma brucei cdc2-related kinase 1 0.0088 0.0209 0.0761
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Schistosoma mansoni hypothetical protein 0.0274 0.0757 0.1248
Echinococcus multilocularis orexin receptor type 2 0.0274 0.0757 0.0754
Echinococcus granulosus 7tm_1 domain containing protein 0.0274 0.0757 0.0754
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0012 0.0034
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Toxoplasma gondii hypothetical protein 0.0018 0.0003 0.0001
Echinococcus multilocularis G protein coupled receptor 139 0.0426 0.1205 0.1202
Leishmania major beta tubulin 0.016 0.0422 0.1546
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0522 0.1487 0.4494
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0274 0.0757 0.5808
Echinococcus granulosus lysine specific demethylase 5A 0.0116 0.0293 0.029
Toxoplasma gondii PAN/Apple domain-containing protein 0.0029 0.0036 0.0123
Echinococcus granulosus tumor protein p63 0.0331 0.0925 0.0923
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Brugia malayi PAN domain containing protein 0.0029 0.0036 0.0049
Echinococcus multilocularis g protein coupled receptor 0.0274 0.0757 0.0754
Onchocerca volvulus 0.0274 0.0757 0.5808
Onchocerca volvulus 0.0029 0.0036 0.0256
Schistosoma mansoni microtubule-associated protein tau 0.135 0.3925 0.6489
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0308 0.0857 0.3152
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Brugia malayi celfurPC protein 0.1558 0.4538 0.6603
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0082 0.0193 0.1259
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0522 0.1487 0.2456
Echinococcus granulosus glycoprotein Antigen 5 0.0056 0.0115 0.0112
Echinococcus granulosus expressed conserved protein 0.0271 0.0751 0.0748
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0114 0.0288 0.0471
Echinococcus granulosus transmembrane protease serine 3 0.0056 0.0115 0.0112
Echinococcus granulosus cyclin b3 0.0063 0.0137 0.0134
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0042 0.0057
Echinococcus multilocularis neuropeptide Y receptor 0.0274 0.0757 0.0754
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0274 0.0757 0.0754
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Loa Loa (eye worm) hypothetical protein 0.0087 0.0207 0.0296
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.003 0.0335
Loa Loa (eye worm) hypothetical protein 0.0151 0.0397 0.0573
Loa Loa (eye worm) subtilase 0.009 0.0217 0.0311
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0116 0.0294 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0115 0.0186
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0101 0.0098
Trichomonas vaginalis cyclins, putative 0.0103 0.0256 0.0765
Schistosoma mansoni neuropeptide receptor 0.0274 0.0757 0.1248
Echinococcus granulosus g protein coupled receptor 0.0274 0.0757 0.0754
Schistosoma mansoni hypothetical protein 0.0063 0.0138 0.0223
Schistosoma mansoni tar DNA-binding protein 0.0186 0.0499 0.082
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0078 0.0288
Entamoeba histolytica ribosomal RNA methyltransferase, putative 0.0025 0.0025 0.0256
Onchocerca volvulus 0.0274 0.0757 0.5808
Giardia lamblia Kinase, CMGC CDK 0.0088 0.0209 0.1122
Plasmodium vivax patched family protein, putative 0.0018 0.0003 0.0012
Mycobacterium ulcerans lipase LipD 0.007 0.0158 0.2281
Onchocerca volvulus 0.0056 0.0115 0.0862
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0148 0.0211
Brugia malayi Furin-like cysteine rich region family protein 0.0126 0.0323 0.0466
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0158 0.047
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0308 0.0857 0.3152
Onchocerca volvulus 0.0034 0.0052 0.0377
Brugia malayi Niemann-Pick C1 protein precursor 0.0289 0.0802 0.1163
Echinococcus multilocularis tubulin beta 1 chain 0.016 0.0422 0.0419
Echinococcus granulosus neuropeptides capa receptor 0.0274 0.0757 0.0754
Echinococcus multilocularis tubulin, beta 4A class IVa 0.016 0.0422 0.0419
Brugia malayi Ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0938 0.2711 0.3943
Loa Loa (eye worm) hypothetical protein 0.0851 0.2455 0.357
Echinococcus multilocularis neuropeptide Y receptor 0.0274 0.0757 0.0754
Echinococcus granulosus putative ribosomal RNA methyltransferase/cell division FtsJ protein 0.0025 0.0025 0.0022
Echinococcus granulosus inhibitor of apoptosis protein 0.0054 0.0111 0.0108
Loa Loa (eye worm) WD40 repeat protein 0.007 0.0157 0.0224
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.018 0.0651
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0022 0.0032
Echinococcus granulosus beta tubulin 0.016 0.0422 0.0419
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0115 0.0186
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0023 0.0029
Brugia malayi Tubulin beta-1 chain 0.016 0.0422 0.061
Brugia malayi G-protein coupled receptor 0.0274 0.0757 0.1098
Echinococcus multilocularis neuropeptide s receptor 0.0274 0.0757 0.0754
Loa Loa (eye worm) hypothetical protein 0.0087 0.0207 0.0297
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0034 0.0052 0.0181
Schistosoma mansoni hypothetical protein 0.0168 0.0445 0.0731
Leishmania major beta tubulin 0.016 0.0422 0.1546
Schistosoma mansoni ribosomal RNA methyltransferase 0.0025 0.0025 0.0036
Trichomonas vaginalis cyclin B, putative 0.0151 0.0397 0.1192
Loa Loa (eye worm) beta-lactamase 0.007 0.0158 0.0226
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0031 0.0043 0.0146
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0209 0.0624
Loa Loa (eye worm) TYRA-2 protein 0.0274 0.0757 0.1098
Schistosoma mansoni hypothetical protein 0.0031 0.0042 0.0065
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Echinococcus multilocularis serotonin receptor 0.0274 0.0757 0.0754
Echinococcus granulosus alpha 1A adrenergic receptor 0.0274 0.0757 0.0754
Brugia malayi jmjC domain containing protein 0.0116 0.0293 0.0421
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.009 0.0217 0.0789
Echinococcus multilocularis cyclin dependent kinase 0.0088 0.0209 0.0206
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.0158 0.0973
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0938 0.2711 0.8201
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0034 0.0052 0.0113
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.0158 0.0155
Echinococcus granulosus microtubule associated protein 2 0.135 0.3925 0.3923
Echinococcus multilocularis set1:ash2 histone methyltransferase complex 0.0043 0.0078 0.0075
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.0231 0.0332
Loa Loa (eye worm) hypothetical protein 0.0029 0.0036 0.0049
Echinococcus granulosus g protein coupled receptor 0.0274 0.0757 0.0754
Loa Loa (eye worm) hypothetical protein 0.0056 0.0115 0.0163
Brugia malayi AMP-binding enzyme family protein 0.0034 0.0052 0.0071
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0036 0.0049
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0274 0.0757 0.1248
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.009 0.0217 0.0789
Echinococcus multilocularis cyclins 0.0063 0.0137 0.0134
Onchocerca volvulus 0.0026 0.0029 0.0196
Onchocerca volvulus 0.0063 0.0138 0.1038
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.009 0.0217 0.0311
Schistosoma mansoni amine GPCR 0.0274 0.0757 0.1248
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0308 0.0857 0.3152
Brugia malayi Matrixin family protein 0.0045 0.0083 0.0116
Brugia malayi SPRY domain containing protein 0.0043 0.0078 0.0109
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.0158 0.0973
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Loa Loa (eye worm) hypothetical protein 0.0029 0.0036 0.0049
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0034 0.0052 0.0181
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0058 0.0122 0.0196
Loa Loa (eye worm) hypothetical protein 0.041 0.1159 0.1683
Brugia malayi Pre-SET motif family protein 0.0058 0.0122 0.0173
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Plasmodium vivax acetyl-CoA synthetase, putative 0.0034 0.0052 0.0192
Onchocerca volvulus 0.0029 0.0036 0.0256
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0101 0.2686
Plasmodium falciparum acyl-CoA synthetase 0.0087 0.0207 0.0754
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0217 0.0647
Schistosoma mansoni hypothetical protein 0.0274 0.0757 0.1248
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Onchocerca volvulus 0.0095 0.0231 0.1756
Brugia malayi Hemopexin family protein 0.0063 0.0138 0.0196
Loa Loa (eye worm) hypothetical protein 0.0048 0.0094 0.0133
Brugia malayi larval opioid receptor 0.0274 0.0757 0.1098
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0045 0.0083 0.0132
Giardia lamblia High cysteine membrane protein Group 2 0.0642 0.1841 1
Echinococcus granulosus Tubulin beta 2C chain 0.016 0.0422 0.0419
Onchocerca volvulus 0.0058 0.0122 0.0913
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Loa Loa (eye worm) BEN-1 protein 0.016 0.0422 0.061
Giardia lamblia Cyclin A 0.0063 0.0137 0.0729
Loa Loa (eye worm) neuropeptide F receptor 0.0274 0.0757 0.1098
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0274 0.0757 0.0754
Plasmodium vivax acyl-CoA synthetase, putative 0.0087 0.0207 0.0765
Brugia malayi Protein kinase domain containing protein 0.0168 0.0445 0.0643
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0057
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0042 0.0039
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0522 0.1487 0.4494
Brugia malayi rRNA methyltransferase 0.0025 0.0025 0.0032
Brugia malayi hypothetical protein 0.0056 0.0115 0.0163
Leishmania major hypothetical protein, conserved 0.0031 0.0043 0.0146
Loa Loa (eye worm) hypothetical protein 0.0116 0.0294 0.0423
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.046 0.1686
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0522 0.1487 0.4494
Mycobacterium leprae Possible secreted protease 0.009 0.0217 0.7075
Onchocerca volvulus 0.0029 0.0036 0.0256
Echinococcus granulosus cyclin dependent kinase 1 0.0088 0.0209 0.0206
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0938 0.2711 0.4481
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0289 0.0802 0.936
Trypanosoma brucei beta tubulin 0.016 0.0422 0.1546
Brugia malayi Matrixin family protein 0.0045 0.0083 0.0116
Echinococcus granulosus neuropeptides capa receptor 0.0274 0.0757 0.0754
Toxoplasma gondii beta-tubulin, putative 0.016 0.0422 0.1546
Echinococcus multilocularis neuropeptides capa receptor 0.0274 0.0757 0.0754
Trypanosoma cruzi hypothetical protein, conserved 0.0168 0.0445 0.1631
Brugia malayi Melatonin receptor type 1A 0.0274 0.0757 0.1098
Echinococcus granulosus Tubulin beta 2C chain 0.016 0.0422 0.0419
Schistosoma mansoni lozenge 0.0054 0.011 0.0177
Schistosoma mansoni hypothetical protein 0.0274 0.0757 0.1248
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.016 0.0157
Giardia lamblia G2/mitotic-specific cyclin B 0.0151 0.0397 0.2141
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Brugia malayi PAN domain containing protein 0.0029 0.0036 0.0049
Schistosoma mansoni phd/f-box containing protein 0.0031 0.0043 0.0065
Echinococcus multilocularis lysine specific demethylase 5A 0.0116 0.0293 0.029
Echinococcus granulosus neuropeptide Y receptor 0.0274 0.0757 0.0754
Onchocerca volvulus Deterin homolog 0.0054 0.0111 0.0828
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0103 0.0367
Schistosoma mansoni biogenic amine (5HT) receptor 0.0274 0.0757 0.1248
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0103 0.0367
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0057
Loa Loa (eye worm) tubulin beta-2A chain 0.016 0.0422 0.061
Brugia malayi hypothetical protein 0.0274 0.0757 0.1098
Schistosoma mansoni hypothetical protein 0.0071 0.016 0.026
Brugia malayi putative neuropeptide receptor NPR1 0.0274 0.0757 0.1098
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0082 0.0193 0.1259
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0938 0.2711 1
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0056 0.0115 0.0112
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0114 0.0288 0.0861
Echinococcus multilocularis rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Trypanosoma brucei RNA helicase, putative 0.0107 0.0265 0.0969
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0308 0.0857 1
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0168 0.0445 0.164
Echinococcus granulosus jumonji domain containing 1A 0.0031 0.0043 0.0039
Schistosoma mansoni neuropeptide receptor 0.0274 0.0757 0.1248
Plasmodium falciparum large subunit rRNA methyltransferase, putative 0.0025 0.0025 0.008
Echinococcus granulosus Niemann Pick C1 protein 0.0289 0.0802 0.0799
Schistosoma mansoni retinoblastoma binding protein 0.0074 0.017 0.0276
Echinococcus multilocularis rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Echinococcus granulosus Mastin 0.0056 0.0115 0.0112
Schistosoma mansoni jumonji domain containing protein 0.0031 0.0043 0.0065
Echinococcus multilocularis cyclins 0.0063 0.0137 0.0134
Mycobacterium ulcerans beta-lactamase 0.007 0.0158 0.2281
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0054 0.0111 0.0108
Entamoeba histolytica cell division protein kinase 2, putative 0.0088 0.0209 0.2416
Toxoplasma gondii subtilisin SUB8 0.009 0.0217 0.0789
Toxoplasma gondii ribosomal RNA large subunit methyltransferase J protein 0.0025 0.0025 0.0081
Brugia malayi hypothetical protein 0.0274 0.0757 0.1098
Toxoplasma gondii beta-1 tubulin, putative 0.016 0.0422 0.1546
Loa Loa (eye worm) TAR-binding protein 0.0186 0.0499 0.0722
Schistosoma mansoni tar DNA-binding protein 0.0186 0.0499 0.082
Plasmodium vivax FtsJ-like methyltransferase, putative 0.0025 0.0025 0.0092
Echinococcus multilocularis neuropeptide receptor 0.0274 0.0757 0.0754
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0186 0.0499 0.0722
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.009 0.0217 0.0214
Echinococcus multilocularis lysine specific demethylase 6a 0.0031 0.0043 0.0039
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.1025 0.3774
Loa Loa (eye worm) hypothetical protein 0.0087 0.0207 0.0297
Loa Loa (eye worm) hypothetical protein 0.0056 0.0115 0.0163
Echinococcus multilocularis tumor protein p63 0.0331 0.0925 0.0923
Trichomonas vaginalis cyclins, putative 0.0151 0.0397 0.1192
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0034 0.0052 0.0049
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.009 0.0217 0.1448
Schistosoma mansoni hypothetical protein 0.0274 0.0757 0.1248
Loa Loa (eye worm) hypothetical protein 0.0087 0.0207 0.0297
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Loa Loa (eye worm) hypothetical protein 0.0054 0.0112 0.0158
Brugia malayi G-protein coupled receptor 0.0274 0.0757 0.1098
Schistosoma mansoni hypothetical protein 0.012 0.0304 0.0497
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.046 0.1686
Schistosoma mansoni neuropeptide receptor 0.0274 0.0757 0.1248
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0029 0.0036 0.0123
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0054 0.0111 0.0157
Schistosoma mansoni histamine h1 receptor 0.0274 0.0757 0.1248
Schistosoma mansoni survival motor neuron protein 0.0095 0.0231 0.0377
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0116 0.0293 0.029
Toxoplasma gondii subtilisin SUB7 0.009 0.0217 0.0789
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0115 0.0186
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Echinococcus granulosus cyclins 0.0063 0.0137 0.0134
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0116 0.0294 0.2074
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Toxoplasma gondii hypothetical protein 0.0048 0.0092 0.033
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0034 0.0052 0.0834
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Echinococcus multilocularis GPCR, family 2 0.0031 0.0042 0.0039
Echinococcus multilocularis g-protein coupled receptor 0.0274 0.0757 0.0754
Trichomonas vaginalis antibiotic synthetase, putative 0.0034 0.0052 0.0149
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0024 0.0078
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.009 0.0217 0.1448
Echinococcus granulosus lamin 0.0026 0.0029 0.0026
Trichomonas vaginalis cyclin B, putative 0.0151 0.0397 0.1192
Echinococcus multilocularis cyclins 0.0063 0.0137 0.0134
Loa Loa (eye worm) hypothetical protein 0.007 0.0158 0.0226
Schistosoma mansoni hypothetical protein 0.0031 0.0042 0.0065
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0115 0.0186
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0115 0.0186
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0274 0.0757 0.1248
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0036 0.0123
Echinococcus granulosus allatostatin A receptor 0.0274 0.0757 0.0754
Brugia malayi proprotein convertase 2 0.1348 0.392 0.5702
Trypanosoma cruzi beta tubulin, putative 0.016 0.0422 0.1546
Schistosoma mansoni biogenic amine receptor 0.0274 0.0757 0.1248
Trypanosoma cruzi cdc2-related kinase 1 0.0088 0.0209 0.0761
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.009 0.0217 0.0789
Brugia malayi PAN domain containing protein 0.0029 0.0036 0.0049
Loa Loa (eye worm) hypothetical protein 0.0067 0.0148 0.0211
Leishmania major 4-coumarate:coa ligase-like protein 0.0116 0.0294 0.1074
Loa Loa (eye worm) hypothetical protein 0.0168 0.0445 0.0643
Leishmania major hypothetical protein, conserved 0.007 0.0158 0.0573
Schistosoma mansoni hypothetical protein 0.0056 0.0115 0.0186
Echinococcus multilocularis enteropeptidase 0.0056 0.0115 0.0112
Echinococcus multilocularis Tubulin beta 2C chain 0.016 0.0422 0.0419
Loa Loa (eye worm) beta-tubulin 0.016 0.0422 0.061
Brugia malayi jmjC domain containing protein 0.0031 0.0043 0.0057
Echinococcus multilocularis Protein lozenge 0.0054 0.011 0.0107
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.018 0.0662
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0042 0.0057
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0041 0.0071 0.0099
Loa Loa (eye worm) hypothetical protein 0.0098 0.0239 0.0343
Echinococcus granulosus histone lysine methyltransferase setb 0.0058 0.0122 0.0119
Schistosoma mansoni neuropeptide f receptor 76f 0.0274 0.0757 0.1248
Schistosoma mansoni neuropeptide F-like receptor 0.0274 0.0757 0.1248
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0162 0.043 0.0427
Echinococcus multilocularis microtubule associated protein 2 0.135 0.3925 0.3923
Onchocerca volvulus 0.0274 0.0757 0.5808
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Schistosoma mansoni hypothetical protein 0.007 0.0157 0.0254
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0042 0.0057
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0042 0.0039
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Schistosoma mansoni tar DNA-binding protein 0.0186 0.0499 0.082
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0209 0.0341
Echinococcus multilocularis rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Plasmodium falciparum protein kinase 5 0.0088 0.0209 0.0761
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0078 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0408 0.1151 0.3477
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0162 0.043 0.0427
Echinococcus multilocularis protein patched 0.0124 0.0317 0.0314
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0274 0.0757 0.1248
Brugia malayi Subtilase family protein 0.009 0.0217 0.0311
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0034 0.0052 0.0049
Schistosoma mansoni neuropeptide receptor 0.0426 0.1205 0.1988
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0274 0.0757 0.1248
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0274 0.0757 0.1248
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0022 0.0059
Toxoplasma gondii subtilisin SUB5 0.009 0.0217 0.0789
Brugia malayi AMP-binding enzyme family protein 0.0034 0.0052 0.0071
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0088 0.0209 0.0761
Plasmodium vivax protein kinase Crk2 0.0088 0.0209 0.0772
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0056 0.0115 0.0163
Brugia malayi ORL1-like opioid receptor 0.0274 0.0757 0.1098
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.0099
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0209 0.0624
Leishmania major beta tubulin 0.016 0.0422 0.1546
Brugia malayi CHE-14 protein 0.0124 0.0317 0.0457
Trypanosoma cruzi cdc2-related kinase 1 0.0088 0.0209 0.0761
Trypanosoma cruzi cdc2-related kinase 3 0.0088 0.0209 0.0761
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0308 0.0857 0.1413
Echinococcus granulosus GPCR family 2 0.0031 0.0042 0.0039
Brugia malayi cell division control protein 2 homolog 0.0088 0.0209 0.03
Echinococcus granulosus survival motor neuron protein 1 0.0466 0.1322 0.1319
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0014
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0115 0.0186
Brugia malayi hypothetical protein 0.0274 0.0757 0.1098
Toxoplasma gondii subtilisin SUB11 0.009 0.0217 0.0789
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0034 0.0052 0.0071
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0087 0.0207 0.3338
Loa Loa (eye worm) melatonin receptor type 1A 0.0274 0.0757 0.1098
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0938 0.2711 0.4481
Brugia malayi Matrixin family protein 0.0045 0.0083 0.0116
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0043 0.0057
Toxoplasma gondii subtilisin SUB6 0.009 0.0217 0.0789
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.016 0.026
Trichomonas vaginalis conserved hypothetical protein 0.0408 0.1151 0.3477
Loa Loa (eye worm) tubulin beta-1 chain 0.016 0.0422 0.061
Schistosoma mansoni cyclin B 0.0151 0.0397 0.0651
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0116 0.0294 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0116 0.0294 0.3406
Loa Loa (eye worm) SPRY domain-containing protein 0.004 0.0068 0.0095
Brugia malayi Trypsin-like protease protein 5 0.0056 0.0115 0.0163
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0408 0.1151 0.3477
Schistosoma mansoni hypothetical protein 0.0056 0.0115 0.0186
Brugia malayi Pre-SET motif family protein 0.0403 0.1138 0.1652
Schistosoma mansoni opsin-like receptor 0.0274 0.0757 0.1248
Schistosoma mansoni lamin 0.0026 0.0029 0.0042
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0209 0.0624
Echinococcus multilocularis lamin dm0 0.0026 0.0029 0.0026
Echinococcus granulosus beta tubulin 0.016 0.0422 0.0419
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0274 0.0757 0.0754
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0022 0.0058
Brugia malayi hypothetical protein 0.0274 0.0757 0.1098
Trypanosoma brucei mitotic cyclin 6 0.0151 0.0397 0.1453
Trichomonas vaginalis cyclins, putative 0.0151 0.0397 0.1192
Entamoeba histolytica hypothetical protein 0.0071 0.016 0.184
Echinococcus granulosus lysine specific demethylase 6a 0.0031 0.0043 0.0039
Echinococcus granulosus intermediate filament protein 0.0026 0.0029 0.0026
Mycobacterium tuberculosis Probable hydrolase 0.007 0.0158 0.0973
Echinococcus multilocularis g protein coupled receptor 0.0274 0.0757 0.0754
Toxoplasma gondii hypothetical protein 0.0059 0.0125 0.0449
Trypanosoma brucei beta tubulin 0.016 0.0422 0.1546
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.009 0.0217 0.354
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase isozyme L3, putative 0.0938 0.2711 1
Leishmania major cyclin 0.0151 0.0397 0.1453
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.018 0.0651
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.003 0.0111
Plasmodium vivax subtilisin-like protease 2, putative 0.009 0.0217 0.0799
Loa Loa (eye worm) hypothetical protein 0.0466 0.1322 0.192
Onchocerca volvulus 0.0274 0.0757 0.5808
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase BAP1 0.0308 0.0857 0.0854
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0087 0.0207 1
Schistosoma mansoni tubulin subunit beta 0.016 0.0422 0.0693
Loa Loa (eye worm) hypothetical protein 0.2351 0.6872 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0031 0.0043 0.0146
Echinococcus granulosus cyclins 0.0063 0.0137 0.0134
Loa Loa (eye worm) hypothetical protein 0.0029 0.0036 0.0049
Schistosoma mansoni hypothetical protein 0.2071 0.6047 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0116 0.0294 0.5199
Echinococcus multilocularis rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Echinococcus multilocularis rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0054 0.0111 0.0108
Leishmania major beta tubulin 0.016 0.0422 0.1546
Loa Loa (eye worm) TK/EGFR protein kinase 0.0126 0.0323 0.0466
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.1025 0.3774
Echinococcus multilocularis survival motor neuron protein 1 0.0466 0.1322 0.1319
Schistosoma mansoni hypothetical protein 0.0107 0.0265 0.0434
Trypanosoma brucei cdc2-related kinase 3 0.0088 0.0209 0.0761
Loa Loa (eye worm) hypothetical protein 0.043 0.1216 0.1766
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Echinococcus granulosus neuroendocrine convertase 2 0.1348 0.392 0.3918
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0094 0.0151
Toxoplasma gondii microneme protein MIC17B 0.0029 0.0036 0.0123
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0036 0.0123
Loa Loa (eye worm) hypothetical protein 0.0087 0.0207 0.0297
Echinococcus granulosus neuropeptide receptor 0.0426 0.1205 0.1202
Trichomonas vaginalis cyclins, putative 0.0063 0.0137 0.0406
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.1139 0.3305 0.3303
Brugia malayi Kringle domain containing protein 0.0168 0.0445 0.0643
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0063 0.0137 0.0134
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0058 0.0122 0.0196
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Echinococcus multilocularis 0.1558 0.4538 0.4537
Schistosoma mansoni adenoreceptor 0.0274 0.0757 0.1248
Brugia malayi beta-lactamase family protein 0.007 0.0158 0.0226
Loa Loa (eye worm) hypothetical protein 0.0056 0.0115 0.0163
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0023 0.002
Loa Loa (eye worm) hypothetical protein 0.0087 0.0207 0.0297
Brugia malayi G protein-coupled receptor F59B2.13 0.0274 0.0757 0.1098
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0274 0.0757 0.1248
Loa Loa (eye worm) hypothetical protein 0.0029 0.0036 0.0049
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0034 0.0052 0.0834
Echinococcus granulosus set1:ash2 histone methyltransferase complex 0.0043 0.0078 0.0075
Trypanosoma brucei beta tubulin 0.016 0.0422 0.1546
Brugia malayi PAN domain containing protein 0.0029 0.0036 0.0049
Trichomonas vaginalis hypothetical protein 0.0408 0.1151 0.3477
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0522 0.1487 0.4494
Brugia malayi beta-lactamase family protein 0.007 0.0158 0.0226
Mycobacterium ulcerans acyl-CoA synthetase 0.0116 0.0294 0.5199
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0103 0.0367
Trichomonas vaginalis tubulin epsilon chain, putative 0.016 0.0422 0.1268
Echinococcus multilocularis lamin 0.0026 0.0029 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.0116 0.0294 0.5199
Echinococcus granulosus membrane bound transcription factor site 1 0.009 0.0217 0.0214
Schistosoma mansoni furin-1 (S08 family) 0.0917 0.2649 0.4379
Trichomonas vaginalis conserved hypothetical protein 0.0408 0.1151 0.3477
Brugia malayi PAN domain containing protein 0.0029 0.0036 0.0049
Echinococcus granulosus wd40 repeat 0.0074 0.017 0.0167
Loa Loa (eye worm) ubiquitin C-terminal hydrolase UCH-L5 0.0308 0.0857 0.1243
Echinococcus multilocularis serotonin receptor 0.0274 0.0757 0.0754
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0024 0.0078
Echinococcus granulosus protein will die slowly 0.007 0.0157 0.0154
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0274 0.0757 0.1098
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0024 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0408 0.1151 0.3477
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0274 0.0757 0.1248
Loa Loa (eye worm) endoprotease bli-4 0.1966 0.5738 0.8349
Echinococcus multilocularis cyclin B3 1 0.0063 0.0137 0.0134
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Giardia lamblia FtsJ cell division protein, putative 0.0025 0.0025 0.0119
Schistosoma mansoni hypothetical protein 0.0408 0.1151 0.19
Schistosoma mansoni intermediate filament proteins 0.0026 0.0029 0.0042
Brugia malayi intermediate filament protein 0.0026 0.0029 0.0037
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0274 0.0757 0.0754
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0308 0.0857 0.1413
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.0158 0.0973
Echinococcus multilocularis cyclin dependent kinase 5 0.0088 0.0209 0.0206
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.0158 0.0226
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.016 0.0157
Onchocerca volvulus Matrix metalloproteinase homolog 0.0099 0.0243 0.1849
Brugia malayi G protein-coupled receptor 0.0274 0.0757 0.1098
Schistosoma mansoni jumonji/arid domain-containing protein 0.0116 0.0293 0.0479
Schistosoma mansoni myosin xvIII 0.0274 0.0757 0.1248
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0034 0.0052 0.0071
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0054 0.0111 0.0178
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0034 0.0052 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0217 0.0647
Echinococcus granulosus serotonin receptor 0.0274 0.0757 0.0754
Schistosoma mansoni phosphatidylserine receptor 0.0031 0.0043 0.0065
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0023 0.0061
Loa Loa (eye worm) hypothetical protein 0.0054 0.0111 0.0157
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0029 0.0037
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0052 0.0113
Leishmania major 4-coumarate:coa ligase-like protein 0.0116 0.0294 0.1074
Echinococcus multilocularis protein will die slowly 0.007 0.0157 0.0154
Leishmania major acetyl-CoA synthetase, putative 0.0034 0.0052 0.0181
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Echinococcus multilocularis jumonji domain containing 1A 0.0031 0.0043 0.0039
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0056 0.0115 0.0112
Loa Loa (eye worm) hypothetical protein 0.1966 0.5738 0.8349
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0217 0.0647
Leishmania major hypothetical protein, conserved 0.0168 0.0445 0.1631
Trichomonas vaginalis retinoblastoma binding protein, putative 0.0074 0.017 0.0506
Echinococcus granulosus tachykinin peptides receptor 99D 0.0274 0.0757 0.0754
Echinococcus multilocularis cyclins 0.0063 0.0137 0.0134
Onchocerca volvulus 0.0026 0.0029 0.0196
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.0239 0.0343
Leishmania major beta tubulin 0.016 0.0422 0.1546
Loa Loa (eye worm) hypothetical protein 0.041 0.1159 0.1683
Giardia lamblia Kinase, CMGC CDK 0.0088 0.0209 0.1122
Toxoplasma gondii calcium binding egf domain-containing protein 0.0041 0.0071 0.0251
Trichomonas vaginalis cyclin D, putative 0.0063 0.0137 0.0406
Echinococcus multilocularis fmrfamide receptor 0.0274 0.0757 0.0754
Echinococcus granulosus cyclins 0.0063 0.0137 0.0134
Loa Loa (eye worm) TK/ROR protein kinase 0.0168 0.0445 0.0643
Schistosoma mansoni hypothetical protein 0.0054 0.0111 0.0178
Brugia malayi RNA recognition motif domain containing protein 0.0186 0.0499 0.0722
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.0116 0.0112
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0031 0.0043 0.0146
Toxoplasma gondii patched family protein 0.0018 0.0003 0.0001
Schistosoma mansoni amine GPCR 0.0274 0.0757 0.1248
Loa Loa (eye worm) hypothetical protein 0.0124 0.0317 0.0457
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0448 0.1271 1
Echinococcus multilocularis cyclins 0.0063 0.0137 0.0134
Echinococcus multilocularis JmjC domain containing protein 4 0.0031 0.0043 0.0039
Brugia malayi follicle stimulating hormone receptor 0.0274 0.0757 0.1098
Brugia malayi hypothetical protein 0.0466 0.1322 0.192
Onchocerca volvulus Matrilysin homolog 0.0099 0.0243 0.1849
Loa Loa (eye worm) hypothetical protein 0.0034 0.0052 0.0071
Echinococcus multilocularis beta tubulin 0.016 0.0422 0.0419
Plasmodium vivax ubiquitin C-terminal hydrolase, family 1, putative 0.0308 0.0857 0.316
Mycobacterium ulcerans hydrolase 0.0054 0.0112 0.1282
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0274 0.0757 0.1098
Echinococcus granulosus g protein coupled receptor 0.0274 0.0757 0.0754
Echinococcus multilocularis laminin 0.0041 0.0071 0.0068
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0029 0.0037
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0034 0.0052 0.0113
Echinococcus multilocularis tubulin subunit beta 0.016 0.0422 0.0419
Onchocerca volvulus 0.0029 0.0036 0.0256
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0158 0.047
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Echinococcus multilocularis tissue type plasminogen activator 0.0168 0.0445 0.0442
Loa Loa (eye worm) hypothetical protein 0.0176 0.047 0.068
Entamoeba histolytica hypothetical protein 0.0071 0.016 0.184
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.3414 1 1
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0034 0.0052 0.0575
Toxoplasma gondii subtilisin SUB9 0.009 0.0217 0.0789
Onchocerca volvulus 0.0274 0.0757 0.5808
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Leishmania major 4-coumarate:coa ligase-like protein 0.0116 0.0294 0.1074
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0022 0.0028
Plasmodium vivax hypothetical protein, conserved 0.007 0.0158 0.0583
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0041 0.0071 0.0099
Onchocerca volvulus 0.0029 0.0036 0.0256
Schistosoma mansoni protein phosphatase 2C 0.0031 0.0043 0.0065
Trichomonas vaginalis cyclin A, putative 0.0151 0.0397 0.1192
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase isozyme L3 0.0938 0.2711 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0014 0.0041
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.0158 0.2281
Loa Loa (eye worm) hypothetical protein 0.0116 0.0294 0.0423
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0036 0.0049
Leishmania major acetyl-CoA synthetase, putative 0.0034 0.0052 0.0181
Echinococcus granulosus Tubulin beta 2C chain 0.016 0.0422 0.0419
Brugia malayi hypothetical protein 0.0274 0.0757 0.1098
Trypanosoma cruzi cdc2-related kinase 3 0.0088 0.0209 0.0761
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.003 0.0099
Loa Loa (eye worm) hypothetical protein 0.0152 0.0399 0.0576
Loa Loa (eye worm) hypothetical protein 0.0029 0.0036 0.0049
Schistosoma mansoni biogenic amine receptor 0.0274 0.0757 0.1248
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Echinococcus granulosus biogenic amine 5HT receptor 0.0274 0.0757 0.0754
Echinococcus multilocularis neuropeptide receptor 0.0426 0.1205 0.1202
Loa Loa (eye worm) hypothetical protein 0.0029 0.0036 0.0049
Loa Loa (eye worm) hypothetical protein 0.0938 0.2711 0.3943
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0158 0.0257
Giardia lamblia Furin precursor putative serine protease 0.0432 0.1222 0.6634
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0274 0.0757 0.1248
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0158 0.047
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0274 0.0757 0.0754
Onchocerca volvulus 0.0274 0.0757 0.5808
Loa Loa (eye worm) trypsin family protein 0.0056 0.0115 0.0163
Echinococcus granulosus dro:myosuppressin receptor 0.0274 0.0757 0.0754
Brugia malayi Trypsin family protein 0.0056 0.0115 0.0163
Schistosoma mansoni ubiquitinyl hydrolase-BAP1 (C12 family) 0.0308 0.0857 0.1413
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0054 0.0112 0.0158
Schistosoma mansoni amine GPCR 0.0274 0.0757 0.1248
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0938 0.2711 0.8201
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0151 0.0397 0.1453
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0274 0.0757 0.1248
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0034 0.0052 0.0181
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0034 0.0052 0.0113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0274 0.0757 0.1098
Loa Loa (eye worm) SPRY domain-containing protein 0.0043 0.0078 0.0109
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Brugia malayi neuroendocrine convertase 1 precursor 0.15 0.4368 0.6354
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0115 0.0186
Schistosoma mansoni opsin-like receptor 0.0274 0.0757 0.1248
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.041 0.1159 0.1912
Brugia malayi jmjC domain containing protein 0.0031 0.0043 0.0057
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0158 0.0257
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0034 0.0052 0.0181
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0041 0.0071 0.0113
Plasmodium falciparum tubulin beta chain 0.016 0.0422 0.1546
Echinococcus granulosus Tolloid protein 1 0.0041 0.0071 0.0068
Echinococcus granulosus sterol regulatory element binding protein 0.0124 0.0317 0.0314
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0274 0.0757 0.0754
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1597 0.4651 0.465
Echinococcus granulosus neuropeptide Y receptor 0.0274 0.0757 0.0754
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0036 0.0123
Onchocerca volvulus 0.0056 0.0115 0.0862
Toxoplasma gondii subtilisin SUB10 0.009 0.0217 0.0789
Echinococcus multilocularis Tubulin beta 2C chain 0.016 0.0422 0.0419
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Brugia malayi Tachykinin-like peptides receptor 99D 0.2351 0.6872 1
Schistosoma mansoni egf-like domain protein 0.0041 0.0071 0.0113
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0308 0.0857 0.0854
Echinococcus granulosus enteropeptidase 0.0056 0.0115 0.0112
Onchocerca volvulus 0.0045 0.0083 0.0615
Echinococcus multilocularis phd:f box containing protein 0.0031 0.0043 0.0039
Loa Loa (eye worm) hypothetical protein 0.0045 0.0083 0.0116
Onchocerca volvulus 0.0029 0.0036 0.0256
Loa Loa (eye worm) cyclin domain-containing protein 0.0063 0.0137 0.0195
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.009 0.0217 0.0311
Echinococcus multilocularis fmrfamide receptor 0.0274 0.0757 0.0754
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.018 0.5
Onchocerca volvulus 0.007 0.0157 0.1182
Loa Loa (eye worm) hypothetical protein 0.0054 0.0111 0.0157
Echinococcus multilocularis Tubulin beta 2C chain 0.016 0.0422 0.0419
Entamoeba histolytica hypothetical protein 0.0071 0.016 0.184
Echinococcus granulosus tubulin beta 4A class IVa 0.016 0.0422 0.0419
Loa Loa (eye worm) hypothetical protein 0.0151 0.0397 0.0573
Echinococcus granulosus rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Schistosoma mansoni tar DNA-binding protein 0.0186 0.0499 0.082
Loa Loa (eye worm) hypothetical protein 0.009 0.0217 0.0311
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0158 0.0573
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0057
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Brugia malayi RNA binding protein 0.0186 0.0499 0.0722
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.018 1
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.018 0.0176
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0034 0.0052 0.0834
Schistosoma mansoni jumonji domain containing protein 0.0116 0.0293 0.0479
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0054 0.0111 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0317 0.095
Brugia malayi AMP-binding enzyme family protein 0.0116 0.0294 0.0423
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0024 0.0078
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0058 0.0122 0.0119
Schistosoma mansoni tyrosine kinase 0.0126 0.0323 0.0529
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0124 0.0317 0.0457
Plasmodium vivax SET domain protein, putative 0.0058 0.0122 0.0449
Loa Loa (eye worm) G-protein coupled receptor 0.0274 0.0757 0.1098
Onchocerca volvulus Arrow homolog 0.0041 0.0071 0.0523
Brugia malayi PAN domain containing protein 0.0029 0.0036 0.0049
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0115 0.0186
Plasmodium vivax subtilisin-like serine protease, putative 0.009 0.0217 0.0799
Plasmodium vivax ribosomal RNA large subunit methyltransferase J, putative 0.0025 0.0025 0.0092
Plasmodium falciparum subtilisin-like protease 3 0.009 0.0217 0.0788
Mycobacterium leprae PROBABLE HYDROLASE 0.0054 0.0112 0.3094
Plasmodium falciparum subtilisin-like protease 1 0.009 0.0217 0.0788
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0432 0.1222 0.3692
Onchocerca volvulus 0.0029 0.0036 0.0256
Loa Loa (eye worm) RNA binding protein 0.0186 0.0499 0.0722
Trichomonas vaginalis conserved hypothetical protein 0.0408 0.1151 0.3477
Trichomonas vaginalis conserved hypothetical protein 0.0408 0.1151 0.3477
Schistosoma mansoni lamin 0.0026 0.0029 0.0042
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0056 0.0115 0.0112
Toxoplasma gondii subtilisin SUB2 0.009 0.0217 0.0789
Leishmania major beta tubulin 0.016 0.0422 0.1546
Loa Loa (eye worm) hypothetical protein 0.0056 0.0115 0.0163
Entamoeba histolytica acyl-CoA synthetase, putative 0.0116 0.0294 0.3406
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0101 0.0098
Entamoeba histolytica acyl-coA synthetase, putative 0.0116 0.0294 0.3406
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0036 0.0049
Loa Loa (eye worm) hypothetical protein 0.0045 0.0083 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0217 0.0647
Brugia malayi Dopamine receptor protein 2 0.0274 0.0757 0.1098
Toxoplasma gondii hypothetical protein 0.0027 0.003 0.01
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0043 0.0057
Echinococcus granulosus cyclins 0.0063 0.0137 0.0134
Echinococcus multilocularis rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.009 0.0217 0.1448
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.1966 0.5738 0.9489
Brugia malayi Trypsin family protein 0.0056 0.0115 0.0163
Schistosoma mansoni hypothetical protein 0.012 0.0304 0.0497
Onchocerca volvulus 0.0116 0.0294 0.2239
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0101 0.051
Onchocerca volvulus 0.0274 0.0757 0.5808
Echinococcus granulosus 7TM GPCR rhodopsin 0.0274 0.0757 0.0754
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0274 0.0757 0.0754
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0022 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0186 0.0499 0.082
Schistosoma mansoni alpha-1 adrenergic receptor 0.0274 0.0757 0.1248
Echinococcus multilocularis wd40 repeat 0.0074 0.017 0.0167
Brugia malayi Dopamine receptor 0.0274 0.0757 0.1098
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0274 0.0757 0.0754
Trichomonas vaginalis ribosomal RNA methyltransferase, putative 0.0025 0.0025 0.0066
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0022 0.0071
Brugia malayi Fibulin-1 precursor 0.0041 0.0071 0.0099
Brugia malayi hypothetical protein 0.0025 0.0024 0.0031
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.009 0.0217 0.0214
Echinococcus granulosus Tubulin beta 2C chain 0.016 0.0422 0.0419
Echinococcus multilocularis cyclins 0.0063 0.0137 0.0134
Brugia malayi neuropeptide F receptor 0.0274 0.0757 0.1098
Mycobacterium ulcerans hypothetical protein 0.0116 0.0294 0.5199
Onchocerca volvulus 0.0151 0.0397 0.303
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1139 0.3305 1
Brugia malayi beta-lactamase 0.007 0.0158 0.0226
Brugia malayi PAN domain containing protein 0.0029 0.0036 0.0049
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0087 0.0207 0.1372
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0137 0.0406
Echinococcus granulosus rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Brugia malayi hypothetical protein 0.0274 0.0757 0.1098
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0031 0.0043 0.0146
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0116 0.0294 0.5199
Schistosoma mansoni tubulin subunit beta 0.016 0.0422 0.0693
Brugia malayi hypothetical protein 0.043 0.1216 0.1766
Schistosoma mansoni tubulin subunit beta 0.016 0.0422 0.0693
Loa Loa (eye worm) hypothetical protein 0.0056 0.0115 0.0163
Trichomonas vaginalis antibiotic synthetase, putative 0.0034 0.0052 0.0149
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0101 0.051
Echinococcus multilocularis cyclin dependent kinase 1 0.0088 0.0209 0.0206
Mycobacterium leprae conserved hypothetical protein 0.007 0.0158 0.4855
Trypanosoma cruzi cyclin, putative 0.0151 0.0397 0.1453
Brugia malayi GnHR receptor homolog 0.0274 0.0757 0.1098
Echinococcus granulosus rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0078 0.0227
Loa Loa (eye worm) hypothetical protein 0.043 0.1216 0.1766
Onchocerca volvulus 0.0274 0.0757 0.5808
Echinococcus multilocularis Mastin 0.0056 0.0115 0.0112
Onchocerca volvulus 0.0056 0.0115 0.0862
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0063 0.0137 0.0134
Toxoplasma gondii beta tubulin 0.016 0.0422 0.1546
Brugia malayi sulfakinin receptor protein 0.0274 0.0757 0.1098
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0032
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0158 0.047
Echinococcus multilocularis Furin 1 0.0522 0.1487 0.1485
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Schistosoma mansoni inhibitor of apoptosis protein 0.0054 0.0111 0.0178
Brugia malayi hypothetical protein 0.0274 0.0757 0.1098
Echinococcus multilocularis sterol regulatory element binding protein 0.0124 0.0317 0.0314
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0217 0.0647
Echinococcus granulosus Tubulin beta 2C chain 0.016 0.0422 0.0419
Loa Loa (eye worm) matrix metalloproteinase 0.0045 0.0083 0.0116
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.046 0.1686
Plasmodium falciparum SPRY domain, putative 0.0043 0.0078 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0408 0.1151 0.3477
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Echinococcus granulosus tar DNA binding protein 0.0186 0.0499 0.0496
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0274 0.0757 0.0754
Entamoeba histolytica tubulin family protein 0.016 0.0422 0.4905
Echinococcus granulosus neuropeptide receptor 0.0274 0.0757 0.0754
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0031
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.0099
Loa Loa (eye worm) tubulin beta-4 chain 0.016 0.0422 0.061
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0158 0.0573
Brugia malayi PAN domain containing protein 0.0029 0.0036 0.0049
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0293 0.0815 0.1344
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0938 0.2711 0.4481
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.041 0.1159 0.1912
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0022 0.0071
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.1025 0.3774
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0116 0.0294 0.5199
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0308 0.0857 0.0854
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.0099
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0274 0.0757 0.0754
Toxoplasma gondii microneme protein, putative 0.0029 0.0036 0.0123
Loa Loa (eye worm) hypothetical protein 0.007 0.0158 0.0226
Loa Loa (eye worm) RecQ helicase 0.0024 0.0023 0.0029
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0274 0.0757 0.1098
Toxoplasma gondii patched family protein 0.0018 0.0003 0.0001
Onchocerca volvulus 0.0029 0.0036 0.0256
Leishmania major beta tubulin 0.016 0.0422 0.1546
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.0239 0.0343
Loa Loa (eye worm) BEN-1 protein 0.016 0.0422 0.061
Schistosoma mansoni amine GPCR 0.0274 0.0757 0.1248
Echinococcus granulosus biogenic amine 5HT receptor 0.0274 0.0757 0.0754
Echinococcus multilocularis somatostatin receptor 0.0274 0.0757 0.0754
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.0158 0.0973
Leishmania major beta tubulin 0.016 0.0422 0.1546
Entamoeba histolytica cyclin, putative 0.0063 0.0137 0.157
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0136 0.0489
Echinococcus multilocularis inhibitor of apoptosis protein 0.0054 0.0111 0.0108
Onchocerca volvulus 0.0054 0.0111 0.0828
Onchocerca volvulus 0.0274 0.0757 0.5808
Brugia malayi Matrixin family protein 0.0045 0.0083 0.0116
Brugia malayi Protein kinase domain containing protein 0.0088 0.0209 0.03
Echinococcus multilocularis cyclin b3 0.0063 0.0137 0.0134
Echinococcus multilocularis dro:myosuppressin receptor 0.0274 0.0757 0.0754
Leishmania major beta tubulin 0.016 0.0422 0.1546
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Brugia malayi PAN domain containing protein 0.0029 0.0036 0.0049
Loa Loa (eye worm) matrixin family protein 0.0099 0.0243 0.035
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0088 0.0209 0.03
Leishmania major beta tubulin 0.016 0.0422 0.1546
Brugia malayi AMP-binding enzyme family protein 0.0034 0.0052 0.0071
Loa Loa (eye worm) hypothetical protein 0.0116 0.0294 0.0423
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0274 0.0757 0.1248
Echinococcus multilocularis G-protein coupled receptor, putative 0.0274 0.0757 0.0754
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0274 0.0757 0.1098
Echinococcus multilocularis fibrillin 1 0.0041 0.0073 0.007
Onchocerca volvulus 0.0168 0.0445 0.3401
Echinococcus granulosus cyclin dependent kinase 5 0.0088 0.0209 0.0206
Schistosoma mansoni hypothetical protein 0.0067 0.0148 0.024
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Leishmania major beta tubulin 0.016 0.0422 0.1546
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0403 0.1138 0.1652
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0274 0.0757 0.1248
Plasmodium falciparum cyclin 0.0063 0.0137 0.0494
Onchocerca volvulus 0.0029 0.0036 0.0256
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0029 0.0037
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0938 0.2711 1
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0034 0.0052 0.0181
Schistosoma mansoni hypothetical protein 0.0095 0.0231 0.0377
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0274 0.0757 0.1248
Brugia malayi AMP-binding enzyme family protein 0.0116 0.0294 0.0423
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Echinococcus multilocularis rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.018 0.2739
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Onchocerca volvulus 0.009 0.0217 0.1645
Schistosoma mansoni cyclin B3 0.0063 0.0137 0.0222
Trichomonas vaginalis esterase, putative 0.007 0.0158 0.047
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0036 0.0123
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0042 0.0039
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0115 0.0186
Brugia malayi ribosomal RNA methyltransferase 0.0025 0.0025 0.0032
Schistosoma mansoni site-1 peptidase (S08 family) 0.009 0.0217 0.0354
Leishmania major beta tubulin 0.016 0.0422 0.1546
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0274 0.0757 0.1098
Mycobacterium tuberculosis Conserved protein 0.007 0.0158 0.0973
Echinococcus granulosus orexin receptor type 2 0.0274 0.0757 0.0754
Echinococcus granulosus neuropeptide receptor A26 0.0274 0.0757 0.0754
Brugia malayi hypothetical protein 0.0153 0.0402 0.058
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0274 0.0757 0.1098
Echinococcus multilocularis ribosomal RNA large subunit methyltransferase 0.0025 0.0025 0.0022
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0308 0.0857 0.0854
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0115 0.0186
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0522 0.1487 0.4494
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.0239 0.0343
Echinococcus granulosus g-protein coupled receptor 0.0274 0.0757 0.0754
Brugia malayi hypothetical protein 0.0274 0.0757 0.1098
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0022 0.0071
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.018 0.0176
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0036 0.0049
Toxoplasma gondii kringle domain-containing protein 0.0168 0.0445 0.1631
Schistosoma mansoni tubulin subunit beta 0.016 0.0422 0.0693
Trichomonas vaginalis cyclin D, putative 0.0063 0.0137 0.0406
Toxoplasma gondii microneme protein MIC17C 0.0029 0.0036 0.0123
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.009 0.0217 0.354
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.018 0.0292
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0938 0.2711 0.2709
Trichomonas vaginalis conserved hypothetical protein 0.0408 0.1151 0.3477
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0274 0.0757 0.0754
Brugia malayi Cyclin, N-terminal domain containing protein 0.0151 0.0397 0.0573
Toxoplasma gondii patched family protein 0.0018 0.0003 0.0001
Echinococcus multilocularis Tolloid protein 1 0.0041 0.0071 0.0068
Brugia malayi hypothetical protein 0.0274 0.0757 0.1098
Echinococcus multilocularis transmembrane protease serine 3 0.0056 0.0115 0.0112
Echinococcus multilocularis Tubulin beta 2C chain 0.016 0.0422 0.0419
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0308 0.0857 0.3152
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0031 0.0043 0.0146
Trypanosoma brucei 2'-O-ribose RNA methyltransferase SPB1 homolog 0.0025 0.0025 0.0081
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0274 0.0757 0.0754
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0217 0.0647
Onchocerca volvulus 0.043 0.1216 0.9342
Trichomonas vaginalis tubulin epsilon chain, putative 0.016 0.0422 0.1268
Brugia malayi RE15519p 0.0274 0.0757 0.1098
Onchocerca volvulus 0.0274 0.0757 0.5808
Loa Loa (eye worm) tubulin beta chain 0.016 0.0422 0.061
Schistosoma mansoni acetyl-CoA synthetase 0.0034 0.0052 0.0081
Schistosoma mansoni growth hormone secretagogue receptor 0.0274 0.0757 0.1248
Echinococcus granulosus cyclins 0.0063 0.0137 0.0134
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0034 0.0052 0.0181
Schistosoma mansoni opsin-like receptor 0.0274 0.0757 0.1248
Echinococcus multilocularis g protein coupled receptor 0.0274 0.0757 0.0754
Echinococcus granulosus tm gpcr rhodopsin 0.0274 0.0757 0.0754
Echinococcus granulosus somatostatin receptor 0.0274 0.0757 0.0754
Loa Loa (eye worm) hypothetical protein 0.0074 0.017 0.0243
Trichomonas vaginalis conserved hypothetical protein 0.0408 0.1151 0.3477
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0274 0.0757 0.1248
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0115 0.0186
Echinococcus multilocularis protein dispatched 1 0.0142 0.0368 0.0365
Plasmodium falciparum subtilisin-like protease 2 0.009 0.0217 0.0788
Entamoeba histolytica hypothetical protein 0.0071 0.016 0.184
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0036 0.0123
Trichomonas vaginalis tubulin, putative 0.016 0.0422 0.1268
Schistosoma mansoni cercarial elastase (S01 family) 0.0056 0.0115 0.0186
Echinococcus granulosus rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0031 0.0043 0.0065
Loa Loa (eye worm) ribosomal RNA methyltransferase 0.0025 0.0025 0.0032
Schistosoma mansoni trithorax protein ash2 0.0043 0.0078 0.0124
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.009 0.0217 0.354
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0274 0.0757 0.0754
Echinococcus granulosus tubulin beta 1 chain 0.016 0.0422 0.0419
Entamoeba histolytica cyclin family protein 0.0063 0.0137 0.157
Entamoeba histolytica cyclin, putative 0.0151 0.0397 0.4609
Onchocerca volvulus 0.0274 0.0757 0.5808
Loa Loa (eye worm) hypothetical protein 0.007 0.0158 0.0226
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0274 0.0757 0.1248
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.1025 0.3774
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0274 0.0757 0.1248
Plasmodium vivax tubulin beta chain, putative 0.016 0.0422 0.1556
Trypanosoma cruzi cyclin 6, putative 0.0151 0.0397 0.1453
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0116 0.0294 0.2074
Echinococcus multilocularis tar DNA binding protein 0.0186 0.0499 0.0496
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0036 0.0123
Loa Loa (eye worm) hypothetical protein 0.0034 0.0052 0.0071
Onchocerca volvulus Matrilysin homolog 0.0045 0.0083 0.0615
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.0099
Echinococcus granulosus dnaJ subfamily B 0.2071 0.6047 0.6045
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0022 0.0019
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0274 0.0757 0.0754
Brugia malayi jmjC domain containing protein 0.0116 0.0293 0.0421
Echinococcus granulosus fmrfamide receptor 0.0274 0.0757 0.0754
Brugia malayi AMP-binding enzyme family protein 0.0116 0.0294 0.0423
Loa Loa (eye worm) hypothetical protein 0.0058 0.0122 0.0173
Toxoplasma gondii subtilisin SUB12 0.0119 0.0302 0.1102
Mycobacterium leprae Probable lipase LipE 0.007 0.0158 0.4855
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0034 0.0052 0.0181
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.009 0.0217 0.7075
Loa Loa (eye worm) hypothetical protein 0.0088 0.0211 0.0303
Toxoplasma gondii hypothetical protein 0.0029 0.0036 0.0123
Schistosoma mansoni cyclins 0.0063 0.0137 0.0222
Schistosoma mansoni cell division protein ftsj 0.0025 0.0025 0.0036
Brugia malayi Cyclin, N-terminal domain containing protein 0.0151 0.0397 0.0573
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Toxoplasma gondii calcium binding egf domain-containing protein 0.0041 0.0071 0.0251
Loa Loa (eye worm) hypothetical protein 0.0045 0.0083 0.0116
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0057
Echinococcus multilocularis cyclin dependent kinase 1 0.0088 0.0209 0.0206
Brugia malayi Serotonin receptor 0.0274 0.0757 0.1098
Entamoeba histolytica cyclin family protein 0.0063 0.0137 0.157
Onchocerca volvulus 0.0459 0.1301 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0116 0.0293 0.029
Onchocerca volvulus 0.0153 0.0402 0.3069
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0052 0.0113
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0088 0.0209 0.03
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.009 0.0217 0.7075
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0056 0.0115 0.0112
Brugia malayi Will die slowly protein 0.007 0.0157 0.0224
Onchocerca volvulus 0.0274 0.0757 0.5808
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0043 0.0039
Loa Loa (eye worm) proprotein convertase 2 0.0522 0.1487 0.2161
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0274 0.0757 0.1248
Onchocerca volvulus 0.007 0.0158 0.1194
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Loa Loa (eye worm) hypothetical protein 0.0153 0.0402 0.058
Onchocerca volvulus 0.0355 0.0995 0.7642
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0522 0.1487 0.4494
Echinococcus granulosus rhodopsin orphan GPCR 0.0274 0.0757 0.0754
Loa Loa (eye worm) hypothetical protein 0.0274 0.0757 0.1098
Toxoplasma gondii propionate-CoA ligase 0.0034 0.0052 0.0181
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0036 0.0049
Echinococcus granulosus neuropeptide FF receptor 2 0.2351 0.6872 0.6871
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0274 0.0757 0.1248
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase UCHL3 0.0938 0.2711 1
Trichomonas vaginalis set domain proteins, putative 0.0459 0.1301 0.3931
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0052 0.0113
Trichomonas vaginalis cyclin B3, putative 0.0063 0.0137 0.0406
Onchocerca volvulus 0.0048 0.0094 0.0701
Leishmania major beta tubulin 0.016 0.0422 0.1546
Loa Loa (eye worm) hypothetical protein 0.0122 0.0311 0.0449
Trichomonas vaginalis tubulin alpha chain, putative 0.016 0.0422 0.1268
Onchocerca volvulus 0.007 0.0158 0.1194
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0024 0.0078
Echinococcus granulosus sex peptide receptor 0.0274 0.0757 0.0754
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0274 0.0757 0.0754
Echinococcus multilocularis allatostatin A receptor 0.0274 0.0757 0.0754
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.0158 0.0155
Trypanosoma cruzi subtilisin peptidase 0.009 0.0217 0.0789
Echinococcus granulosus tissue type plasminogen activator 0.0168 0.0445 0.0442
Trichomonas vaginalis tubulin gamma chain, putative 0.016 0.0422 0.1268
Brugia malayi TAR-binding protein 0.0186 0.0499 0.0722
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0043 0.0057
Brugia malayi AMP-binding enzyme family protein 0.0034 0.0052 0.0071
Echinococcus granulosus phd:f box containing protein 0.0031 0.0043 0.0039
Toxoplasma gondii microneme protein MIC17A 0.0029 0.0036 0.0123
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0158 0.047
Giardia lamblia Beta tubulin 0.016 0.0422 0.2279
Giardia lamblia Beta tubulin 0.016 0.0422 0.2279
Plasmodium falciparum cysteine repeat modular protein 1 0.0168 0.0445 0.163
Brugia malayi Hypothetical WD-repeat protein F21H12.1 in chromosome II 0.0074 0.017 0.0243
Trypanosoma brucei subtilisin peptidase 0.009 0.0217 0.0789
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0432 0.1222 0.3692
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0023 0.0061
Echinococcus granulosus furin 0.1966 0.5738 0.5737
Echinococcus granulosus bloom syndrome protein 0.0024 0.0023 0.002
Leishmania major beta tubulin 0.016 0.0422 0.1546

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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