Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | histone deacetylase, putative | 0.0132 | 0 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0132 | 0 | 0.5 |
Giardia lamblia | Histone deacetylase | 0.0132 | 0 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0132 | 0 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0132 | 0 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0132 | 0 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0132 | 0 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0132 | 0 | 0.5 |
Entamoeba histolytica | histone deacetylase, putative | 0.0132 | 0 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0132 | 0 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0132 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0201 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0132 | 0 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0132 | 0 | 0.5 |
Trypanosoma brucei | histone deacetylase 1 | 0.0132 | 0 | 0.5 |
Plasmodium falciparum | histone deacetylase 1 | 0.0132 | 0 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0132 | 0 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0132 | 0 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0132 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0201 | 1 | 1 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0132 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0201 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0201 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0201 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0132 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0201 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0201 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0201 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0201 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0201 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.