Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0042 | 0.2391 | 0.2571 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1061 | 0.1098 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0012 | 0.024 | 0.025 |
Mycobacterium tuberculosis | Probable reductase | 0.0105 | 0.698 | 0.8862 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0016 | 0.0546 | 0.1407 |
Brugia malayi | cathepsin L-like precursor | 0.0011 | 0.0182 | 0.019 |
Onchocerca volvulus | 0.0016 | 0.0571 | 0.4428 | |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1061 | 0.1924 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0042 | 0.2391 | 0.8032 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0014 | 0.0389 | 0.1002 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0546 | 0.1407 |
Onchocerca volvulus | 0.0016 | 0.0571 | 0.4428 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.388 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0022 | 0.1005 | 0.1039 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.2719 | 0.9003 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0546 | 0.1407 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0546 | 0.0569 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0546 | 0.0449 |
Brugia malayi | Cytochrome P450 family protein | 0.0014 | 0.0389 | 0.0406 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0117 | 0.7827 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0117 | 0.7827 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.388 | 1 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.388 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0016 | 0.0571 | 0.0586 |
Onchocerca volvulus | 0.0016 | 0.0571 | 0.4428 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0571 | 0.0571 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.2719 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.1061 | 0.1106 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0014 | 0.0389 | 0.0418 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.2142 | 0.7876 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0016 | 0.0546 | 0.0211 |
Toxoplasma gondii | cathepsin CPL | 0.0016 | 0.0571 | 0.0703 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0182 | 0.018 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.005 | 0.2977 | 0.7673 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.388 | 1 |
Loa Loa (eye worm) | cytochrome P450 | 0.0014 | 0.0389 | 0.0396 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0105 | 0.698 | 0.8862 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0105 | 0.698 | 0.8862 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.2719 | 0.2829 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0639 | 0.0657 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0105 | 0.698 | 0.8862 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.1061 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0105 | 0.698 | 0.8862 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0141 | 0.9588 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.388 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.1061 | 0.0903 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0639 | 0.0337 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.2977 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.2977 | 0.2977 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0137 | 0.9302 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0016 | 0.0571 | 0.0614 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0014 | 0.0389 | 0.1002 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0546 | 0.0449 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0016 | 0.0546 | 0.0449 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0105 | 0.698 | 0.8862 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0042 | 0.2391 | 0.8032 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0016 | 0.0546 | 0.2334 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.005 | 0.2977 | 0.7413 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0571 | 0.0596 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0571 | 0.0521 |
Brugia malayi | MAP kinase sur-1 | 0.005 | 0.2977 | 0.3105 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.0571 | 0.21 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1061 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.2719 | 0.2923 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.388 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0022 | 0.1005 | 0.1039 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0016 | 0.0546 | 0.0606 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.005 | 0.2977 | 0.7413 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.2719 | 0.2836 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0546 | 0.1407 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0016 | 0.0571 | 0.0614 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.1061 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.005 | 0.2977 | 0.3105 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0546 | 0.0587 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0016 | 0.0546 | 0.2007 |
Onchocerca volvulus | 0.0016 | 0.0571 | 0.4428 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1061 | 0.1098 |
Brugia malayi | Cytochrome P450 family protein | 0.0051 | 0.3073 | 0.3205 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0571 | 0.0596 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Leishmania major | cysteine peptidase A (CPA) | 0.0016 | 0.0571 | 0.0521 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.005 | 0.2977 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0639 | 0.0657 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0117 | 0.7827 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0016 | 0.0571 | 0.0586 |
Leishmania major | cytochrome p450-like protein | 0.0022 | 0.1005 | 0.1765 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.1061 | 0.1106 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1061 | 0.1098 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.1061 | 0.4954 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.1061 | 0.4954 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0571 | 0.0586 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0182 | 0.018 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.388 | 1 |
Schistosoma mansoni | cytochrome P450 | 0.0014 | 0.0389 | 0.0389 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.388 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.0182 | 0.019 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.2142 | 0.6563 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0042 | 0.2391 | 0.7736 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0042 | 0.2391 | 0.8794 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0571 | 0.0245 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0011 | 0.0182 | 0.0182 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.2977 | 0.7673 |
Onchocerca volvulus | 0.0023 | 0.1061 | 1 | |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.1061 | 1 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.2142 | 1 |
Leishmania major | trypanothione reductase | 0.0046 | 0.2719 | 0.6674 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0546 | 0.1407 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0141 | 0.9588 | 0.9588 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0571 | 0.0521 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.2977 | 0.7673 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0017 | 0.0639 | 0.3726 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0571 | 0.0245 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0546 | 0.1407 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.388 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0571 | 0.0596 |
Loa Loa (eye worm) | fibroinase | 0.0016 | 0.0571 | 0.0586 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0639 | 0.0657 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0639 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0057 | 0.3491 | 0.8997 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0016 | 0.0546 | 0.2334 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0014 | 0.0389 | 0.1002 |
Loa Loa (eye worm) | cysteine protease | 0.0016 | 0.0571 | 0.0586 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0571 | 0.0596 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0016 | 0.0546 | 0.0449 |
Echinococcus multilocularis | 0.0014 | 0.0389 | 0.0406 | |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.2719 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.0182 | 0.019 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.2719 | 0.2829 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0639 | 0.2351 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0022 | 0.1005 | 0.1039 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0546 | 0.1407 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.1061 | 0.1106 |
Echinococcus granulosus | cathepsin l1 | 0.0011 | 0.0182 | 0.0195 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0011 | 0.0182 | 0.019 |
Entamoeba histolytica | cysteine protease, putative | 0.0016 | 0.0571 | 0.2666 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0141 | 0.9588 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0117 | 0.7827 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0571 | 0.0596 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0016 | 0.0546 | 0.1407 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0571 | 0.0596 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0016 | 0.0546 | 0.2007 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0571 | 0.0521 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0546 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0182 | 0.018 |
Onchocerca volvulus | 0.0016 | 0.0571 | 0.4428 | |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.2719 | 0.2836 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0022 | 0.1005 | 0.2591 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.388 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0011 | 0.0182 | 0.0848 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0639 | 0.2351 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0639 | 0.0657 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0016 | 0.0571 | 0.21 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0639 | 0.0657 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.1005 | 0.1048 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.0571 | 0.2666 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0016 | 0.0546 | 0.1833 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0016 | 0.0546 | 0.1833 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.388 | 1 |
Brugia malayi | glutathione reductase | 0.0046 | 0.2719 | 0.2836 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Loa Loa (eye worm) | ctsf protein | 0.0016 | 0.0571 | 0.0586 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.005 | 0.2977 | 0.3098 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.005 | 0.2977 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.005 | 0.2977 | 0.7673 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0011 | 0.0182 | 0.061 |
Onchocerca volvulus | 0.0016 | 0.0571 | 0.4428 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.0571 | 0.2666 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Onchocerca volvulus | Cathepsin F homolog | 0.0016 | 0.0571 | 0.4428 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1061 | 0.1924 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0571 | 0.0596 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Echinococcus granulosus | mitogen activated protein kinase | 0.005 | 0.2977 | 0.3201 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0012 | 0.024 | 0.025 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0546 | 0.5 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.2719 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0016 | 0.0571 | 0.1472 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.2977 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0042 | 0.2391 | 0.7736 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.388 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0546 | 0.1407 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.388 | 1 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.0571 | 0.21 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0546 | 0.0569 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0016 | 0.0546 | 0.2334 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0571 | 0.0521 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.388 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0022 | 0.1005 | 0.2591 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.1061 | 0.0903 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.2977 | 1 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0014 | 0.0389 | 0.1002 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0016 | 0.0571 | 0.21 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.1061 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0546 | 0.1407 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0571 | 0.0245 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0546 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0571 | 0.0596 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0022 | 0.1005 | 0.9172 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0571 | 0.0596 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.1061 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0016 | 0.0546 | 0.2007 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.1005 | 0.1048 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.1061 | 0.0903 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0546 | 0.0546 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0571 | 0.0596 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.2719 | 0.7007 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0571 | 0.0596 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.2719 | 0.7007 |
Onchocerca volvulus | 0.0016 | 0.0571 | 0.4428 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.005 | 0.2977 | 0.7673 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0051 | 0.3073 | 0.3198 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.2719 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0571 | 0.0596 |
Loa Loa (eye worm) | acetyltransferase | 0.0141 | 0.9588 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0011 | 0.0182 | 0.061 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.388 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Plasmodium falciparum | thioredoxin reductase | 0.0016 | 0.0546 | 0.2007 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1061 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.005 | 0.2977 | 0.3105 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0546 | 0.1407 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0546 | 0.1407 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.1061 | 0.0903 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.2719 | 0.3133 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1061 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0016 | 0.0571 | 0.0614 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0016 | 0.0546 | 0.2007 |
Plasmodium falciparum | glutathione reductase | 0.0016 | 0.0546 | 0.2007 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.388 | 1 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0016 | 0.0546 | 0.0606 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.0571 | 0.4428 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Brugia malayi | cytochrome P450 | 0.0014 | 0.0389 | 0.0406 |
Giardia lamblia | Kinase, CMGC MAPK | 0.005 | 0.2977 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.388 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0571 | 0.0571 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0016 | 0.0571 | 0.21 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1061 | 0.1924 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.388 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.2977 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.005 | 0.2977 | 0.7673 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.0571 | 0.4428 |
Trypanosoma brucei | cytochrome P450, putative | 0.0022 | 0.1005 | 0.2591 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0571 | 0.0245 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0571 | 0.0596 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.1061 | 0.4954 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0049 | 0.292 | 0.7525 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0016 | 0.0546 | 0.1407 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0105 | 0.698 | 0.8862 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0571 | 0.0521 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0571 | 0.1918 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.