Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.1432 | 0.1647 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0893 | 0.1027 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0538 | 0.0718 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.7494 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0042 | 0.1137 | 0.1517 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0588 | 0.0676 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0893 | 0.1027 |
Brugia malayi | Pre-SET motif family protein | 0.0206 | 0.8693 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0704 | 0.081 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.1432 | 0.191 |
Onchocerca volvulus | Huntingtin homolog | 0.0129 | 0.5125 | 0.4756 |
Schistosoma mansoni | chromobox protein | 0.0073 | 0.2583 | 0.3446 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.5125 | 0.5896 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.4954 | 0.6611 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.1432 | 0.191 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0588 | 0.0785 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.1252 | 0.059 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.1252 | 0.0732 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0206 | 0.8693 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0073 | 0.2583 | 0.2971 |
Schistosoma mansoni | thyroid hormone receptor | 0.0135 | 0.5414 | 0.7224 |
Echinococcus multilocularis | chromobox protein 1 | 0.0073 | 0.2583 | 0.3446 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.111 | 0.0437 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.1432 | 0.191 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.111 | 0.0581 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0588 | 0.0785 |
Trichomonas vaginalis | chromobox protein, putative | 0.0073 | 0.2583 | 0.2142 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.1662 | 0.1912 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0588 | 0.0676 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.1432 | 0.191 |
Trichomonas vaginalis | chromobox protein, putative | 0.0073 | 0.2583 | 0.2142 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0588 | 0.0785 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0588 | 0.5 |
Onchocerca volvulus | Huntingtin homolog | 0.0129 | 0.5125 | 0.4756 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.1432 | 0.191 |
Brugia malayi | hypothetical protein | 0.0129 | 0.5125 | 0.5896 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.1662 | 0.1912 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.1252 | 0.0732 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.111 | 0.1277 |
Schistosoma mansoni | chromobox protein | 0.0073 | 0.2583 | 0.3446 |
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.111 | 0.1277 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.1432 | 0.191 |
Echinococcus granulosus | chromobox protein 1 | 0.0073 | 0.2583 | 0.3446 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0588 | 0.0785 |
Schistosoma mansoni | thyroid hormone receptor | 0.0135 | 0.5414 | 0.7224 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.7494 | 1 |
Echinococcus granulosus | geminin | 0.018 | 0.7494 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0135 | 0.5414 | 0.7224 |
Echinococcus multilocularis | geminin | 0.018 | 0.7494 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.1662 | 0.1912 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0588 | 0.0785 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0893 | 0.1191 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.111 | 0.0581 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.5125 | 0.5896 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0588 | 0.0785 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0125 | 0.4954 | 0.6611 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0073 | 0.2583 | 0.2971 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0125 | 0.4954 | 0.6611 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0588 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.1432 | 0.1647 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.1432 | 0.191 |
Onchocerca volvulus | 0.0042 | 0.1137 | 0.0466 | |
Echinococcus granulosus | chromobox protein 1 | 0.0073 | 0.2583 | 0.3446 |
Trichomonas vaginalis | set domain proteins, putative | 0.0235 | 1 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0073 | 0.2583 | 0.3446 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.1662 | 0.1912 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.