Detailed information for compound 544366

Basic information

Technical information
  • TDR Targets ID: 544366
  • Name: chromic potassium oxalate
  • MW: 268.14 | Formula: C4HCrKO8
  • H donors: 0 H acceptors: 8 LogP: 2.09 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]C(=O)C(=O)[O-].[O-]C(=O)C(=O)[O-].[Cr+3].[KH+]
  • InChi: 1S/2C2H2O4.Cr.K/c2*3-1(4)2(5)6;;/h2*(H,3,4)(H,5,6);;/q;;+3;+1/p-4
  • InChiKey: LYBOONSXENOKKZ-UHFFFAOYSA-J  


Substructure search Similarity search

Network

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Synonyms

  • potassium; chromium(3+); ethanedioate
  • potassium; chromium(3+); oxalate
  • tris(oxalato)chromate(III)
  • potassium; chromium(+3) cation; oxalate
  • potassium; chromium(+3) cation; ethanedioate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.1662 0.1912
Echinococcus multilocularis thyroid hormone receptor alpha 0.0135 0.5414 0.7224
Loa Loa (eye worm) hypothetical protein 0.0041 0.111 0.1277
Loa Loa (eye worm) hypothetical protein 0.003 0.0588 0.0676
Plasmodium vivax SET domain protein, putative 0.003 0.0588 0.5
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.1252 0.059
Trichomonas vaginalis chromobox protein, putative 0.0073 0.2583 0.2142
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0588 0.5
Trichomonas vaginalis chromobox protein, putative 0.0044 0.1252 0.0732
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.1432 0.191
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.1137 0.1517
Schistosoma mansoni hypothetical protein 0.018 0.7494 1
Schistosoma mansoni thyroid hormone receptor 0.0135 0.5414 0.7224
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.1432 0.191
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.111 0.0437
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.1432 0.191
Trichomonas vaginalis set domain proteins, putative 0.0235 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0588 0.0785
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.1432 0.191
Trichomonas vaginalis chromobox protein, putative 0.0073 0.2583 0.2142
Loa Loa (eye worm) hypothetical protein 0.0036 0.0893 0.1027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.1432 0.191
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.1662 0.1912
Echinococcus granulosus chromobox protein 1 0.0073 0.2583 0.3446
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0588 0.0785
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0538 0.0718
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.111 0.0581
Onchocerca volvulus Huntingtin homolog 0.0129 0.5125 0.4756
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.4954 0.6611
Loa Loa (eye worm) hypothetical protein 0.0053 0.1662 0.1912
Echinococcus multilocularis chromobox protein 1 0.0073 0.2583 0.3446
Loa Loa (eye worm) hypothetical protein 0.0032 0.0704 0.081
Schistosoma mansoni chromobox protein 0.0073 0.2583 0.3446
Loa Loa (eye worm) hypothetical protein 0.0129 0.5125 0.5896
Brugia malayi Heterochromatin protein 1 0.0073 0.2583 0.2971
Echinococcus granulosus geminin 0.018 0.7494 1
Echinococcus granulosus chromobox protein 1 0.0073 0.2583 0.3446
Brugia malayi Pre-SET motif family protein 0.0206 0.8693 1
Brugia malayi Pre-SET motif family protein 0.003 0.0588 0.0676
Onchocerca volvulus Huntingtin homolog 0.0129 0.5125 0.4756
Schistosoma mansoni hypothetical protein 0.0036 0.0893 0.1191
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.111 0.0581
Echinococcus multilocularis geminin 0.018 0.7494 1
Brugia malayi chromobox protein homolog 3 0.0041 0.111 0.1277
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.1432 0.1647
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.2583 0.2971
Schistosoma mansoni hypothetical protein 0.0125 0.4954 0.6611
Brugia malayi hypothetical protein 0.0129 0.5125 0.5896
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0588 0.0785
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0588 0.0785
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.1432 0.191
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.8693 1
Schistosoma mansoni thyroid hormone receptor 0.0135 0.5414 0.7224
Loa Loa (eye worm) hypothetical protein 0.0129 0.5125 0.5896
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.1432 0.191
Trichomonas vaginalis chromobox protein, putative 0.0044 0.1252 0.0732
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.1432 0.1647
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.4954 0.6611
Schistosoma mansoni hypothetical protein 0.018 0.7494 1
Echinococcus multilocularis chromobox protein 1 0.0073 0.2583 0.3446
Schistosoma mansoni chromobox protein 0.0073 0.2583 0.3446
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0588 0.0785
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0893 0.1027
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0588 0.0785
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.1662 0.1912
Onchocerca volvulus 0.0042 0.1137 0.0466

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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