Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0161 | 0.0287 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0049 | 0.0417 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0074 | 0.0131 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0468 | 0.0927 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.0054 | 0.0097 |
Brugia malayi | TAR-binding protein | 0.0129 | 0.0238 | 0.0424 |
Echinococcus granulosus | ferritin | 0.0017 | 0.0011 | 0.002 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0048 | 0.0074 | 0.0131 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0018 | 0.0033 |
Brugia malayi | RNA binding protein | 0.0129 | 0.0238 | 0.0424 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0049 | 0.0417 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0008 | 0.0008 |
Onchocerca volvulus | 0.003 | 0.0036 | 0.0065 | |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0531 | 0.1055 | 0.1882 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0468 | 0.0927 | 0.1654 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0008 | 0.0008 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0025 | 0.0044 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0468 | 0.0927 | 0.1654 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.0059 | 0.0106 |
Loa Loa (eye worm) | aspartic protease BmAsp-1 | 0.0364 | 0.0716 | 0.1277 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0531 | 0.1055 | 0.1882 |
Schistosoma mansoni | bromodomain containing protein | 0.0068 | 0.0114 | 0.0114 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0069 | 0.0117 | 0.0208 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0008 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.1842 | 0.372 | 0.6634 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0077 | 0.0138 |
Echinococcus multilocularis | Ankyrin | 0.0036 | 0.0049 | 0.0088 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0018 | 0.0013 | 0.0023 |
Echinococcus multilocularis | tumor protein p63 | 0.0359 | 0.0704 | 0.1256 |
Schistosoma mansoni | thyroid hormone receptor | 0.0133 | 0.0247 | 0.0247 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.0117 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0364 | 0.0716 | 0.1277 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.0333 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0008 | 0.0014 |
Brugia malayi | Carboxylesterase family protein | 0.0468 | 0.0927 | 0.1654 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0048 | 0.0074 | 0.0131 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0025 | 0.0025 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0049 | 0.0417 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0049 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0494 | 0.098 | 0.1748 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0031 | 0.2007 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0161 | 0.0302 | 0.0539 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0049 | 0.0417 |
Brugia malayi | aspartic protease BmAsp-1, identical | 0.0364 | 0.0716 | 0.1277 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0468 | 0.0927 | 0.1654 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0031 | 0.0214 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0027 | 0.0031 | 0.0214 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0014 | 0.0038 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0125 | 0.0223 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0049 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0082 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.013 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0065 | 0.0115 |
Brugia malayi | Eukaryotic aspartyl protease family protein | 0.0364 | 0.0716 | 0.1277 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0008 | 0.0014 |
Onchocerca volvulus | 0.0468 | 0.0927 | 1 | |
Toxoplasma gondii | aspartyl protease | 0.0364 | 0.0716 | 1 |
Plasmodium falciparum | plasmepsin X | 0.0364 | 0.0716 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0129 | 0.0238 | 0.0424 |
Echinococcus multilocularis | protein patched | 0.0048 | 0.0074 | 0.0131 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0008 | 0.0008 |
Schistosoma mansoni | gabp alpha | 0.0083 | 0.0144 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0031 | 0.0055 |
Brugia malayi | Death domain containing protein | 0.0036 | 0.0049 | 0.0087 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0364 | 0.0716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.0716 | 0.1277 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0048 | 0.0074 | 0.0132 |
Brugia malayi | Carboxylesterase family protein | 0.0468 | 0.0927 | 0.1654 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0364 | 0.0716 | 0.1277 |
Brugia malayi | Bromodomain containing protein | 0.0081 | 0.014 | 0.0249 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.0117 |
Echinococcus multilocularis | geminin | 0.0176 | 0.0333 | 0.0595 |
Echinococcus multilocularis | acetylcholinesterase | 0.2771 | 0.5608 | 1 |
Echinococcus granulosus | geminin | 0.0176 | 0.0333 | 0.0595 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0049 | 0.0088 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0468 | 0.0927 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0468 | 0.0927 | 0.0927 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0238 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0049 | 0.0417 |
Toxoplasma gondii | eukaryotic aspartyl protease superfamily protein | 0.0364 | 0.0716 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0027 | 0.0031 | 0.0214 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0049 | 0.0417 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0074 | 0.0074 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0049 | 0.0417 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0064 | 0.0106 | 0.0189 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0045 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.0716 | 0.1277 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0049 | 0.0465 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0017 | 0.0011 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0468 | 0.0927 | 0.1654 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0049 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0119 | 0.0213 |
Onchocerca volvulus | 0.0052 | 0.0082 | 0.0576 | |
Echinococcus granulosus | GA binding protein alpha chain | 0.0083 | 0.0144 | 0.0256 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0125 | 0.0125 |
Brugia malayi | CHE-14 protein | 0.0048 | 0.0074 | 0.0131 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0161 | 0.0287 |
Toxoplasma gondii | aspartyl protease ASP3 | 0.0364 | 0.0716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0017 | 0.003 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.0333 | 0.0333 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0238 | 0.0238 |
Plasmodium falciparum | plasmepsin VII | 0.0364 | 0.0716 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0112 | 0.0204 | 0.0364 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.007 | 0.007 |
Onchocerca volvulus | 0.0036 | 0.0049 | 0.0207 | |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0069 | 0.0123 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.118 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.0161 | 0.0287 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0011 | 0.0011 |
Onchocerca volvulus | 0.0468 | 0.0927 | 1 | |
Plasmodium falciparum | plasmepsin V | 0.0364 | 0.0716 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0125 | 0.0223 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0788 | 0.1578 | 0.2814 |
Plasmodium vivax | aspartyl protease, putative | 0.0364 | 0.0716 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0125 | 0.5444 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.006 | 0.0106 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0112 | 0.0204 | 1 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0083 | 0.0144 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0017 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.007 | 0.007 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0238 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0087 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0008 | 0.0014 |
Brugia malayi | Fli-1 protein | 0.0251 | 0.0486 | 0.0867 |
Echinococcus granulosus | tumor protein p63 | 0.0359 | 0.0704 | 0.1256 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0238 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Onchocerca volvulus | 0.0468 | 0.0927 | 1 | |
Onchocerca volvulus | 0.0036 | 0.0049 | 0.0207 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0468 | 0.0927 | 0.0927 |
Schistosoma mansoni | netrin receptor unc5 | 0.0036 | 0.0049 | 0.0049 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0049 | 0.0049 |
Echinococcus multilocularis | expressed protein | 0.0017 | 0.0011 | 0.002 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0468 | 0.0927 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0049 | 0.0417 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0027 | 0.0031 | 0.0214 |
Echinococcus multilocularis | expressed conserved protein | 0.0106 | 0.019 | 0.0339 |
Echinococcus multilocularis | neuroligin | 0.0468 | 0.0927 | 0.1654 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0161 | 0.0161 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0031 | 0.0055 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.0031 | 0.5134 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0096 | 0.0171 |
Schistosoma mansoni | patched 1 | 0.0048 | 0.0074 | 0.0074 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0049 | 0.0417 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0052 | 0.0082 | 0.0082 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0125 | 0.5444 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0011 | 0.0011 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0077 | 0.0138 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0025 | 0.0044 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0531 | 0.1055 | 0.1882 |
Echinococcus granulosus | Ankyrin | 0.0036 | 0.0049 | 0.0088 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0238 | 0.0238 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0049 | 0.0417 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0123 | 0.0227 | 0.0404 |
Onchocerca volvulus | 0.0468 | 0.0927 | 1 | |
Plasmodium vivax | aspartyl proteinase, putative | 0.0364 | 0.0716 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0049 | 1 |
Loa Loa (eye worm) | fli-1 protein | 0.0251 | 0.0486 | 0.0867 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0036 | 0.0049 | 0.0049 |
Schistosoma mansoni | ets-related | 0.0251 | 0.0486 | 0.0486 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0064 | 0.0106 | 0.0189 |
Echinococcus granulosus | expressed protein | 0.0017 | 0.0011 | 0.002 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.002 | 0.0017 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0017 | 0.003 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0112 | 0.0204 | 0.0364 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0083 | 0.0144 | 0.0256 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0011 | 0.0011 |
Echinococcus granulosus | death domain containing protein | 0.0036 | 0.0049 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Brugia malayi | Uncoordinated protein 44 | 0.0036 | 0.0049 | 0.0087 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0048 | 0.0074 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Brugia malayi | Carboxylesterase family protein | 0.0468 | 0.0927 | 0.1654 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0031 | 0.0055 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0364 | 0.0716 | 0.1277 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0049 | 0.0417 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.0017 | 0.0062 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0049 | 0.0417 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0231 | 0.0446 | 0.4748 |
Onchocerca volvulus | 0.0364 | 0.0716 | 0.7642 | |
Echinococcus multilocularis | ferritin | 0.0017 | 0.0011 | 0.002 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0069 | 0.0117 | 0.0208 |
Brugia malayi | Carboxylesterase family protein | 0.2771 | 0.5608 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.2771 | 0.5608 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.007 | 0.007 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0014 | 0.0038 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0049 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0034 | 0.0061 |
Loa Loa (eye worm) | RNA binding protein | 0.0129 | 0.0238 | 0.0424 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0027 | 0.0031 | 0.0214 |
Loa Loa (eye worm) | carboxylesterase | 0.0468 | 0.0927 | 0.1654 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0069 | 0.0117 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0036 | 0.0036 |
Echinococcus granulosus | expressed conserved protein | 0.0106 | 0.019 | 0.0339 |
Trichomonas vaginalis | set domain proteins, putative | 0.0238 | 0.0459 | 0.4885 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0031 | 0.0214 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0014 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0031 | 0.0055 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0031 | 0.0214 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0353 | 0.0694 | 0.1237 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0018 | 0.0013 | 0.0023 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0049 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0204 | 0.0364 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0036 | 0.0036 |
Schistosoma mansoni | thyroid hormone receptor | 0.0133 | 0.0247 | 0.0247 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0031 | 0.2007 |
Brugia malayi | Ets-domain containing protein | 0.0083 | 0.0144 | 0.0256 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0045 | 0.008 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0364 | 0.0716 | 0.7693 |
Brugia malayi | Pepsin A precursor | 0.0364 | 0.0716 | 0.1277 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0008 | 0.0014 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0468 | 0.0927 | 0.1654 |
Onchocerca volvulus | Netrin receptor homolog | 0.0036 | 0.0049 | 0.0205 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0468 | 0.0927 | 1 |
Plasmodium falciparum | plasmepsin I | 0.0364 | 0.0716 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0036 | 0.0049 | 0.0087 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0017 | 0.0011 | 0.5 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.0716 | 0.1277 |
Brugia malayi | Ets-domain containing protein | 0.0083 | 0.0144 | 0.0256 |
Brugia malayi | PHD-finger family protein | 0.0027 | 0.003 | 0.0054 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.2771 | 0.5608 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0125 | 0.5444 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0074 | 0.0074 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0468 | 0.0927 | 0.0927 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0209 | 0.04 | 0.0713 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0114 | 0.0208 | 0.0208 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0011 | 0.0011 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0049 | 1 |
Loa Loa (eye worm) | aspartyl protease 6 | 0.0364 | 0.0716 | 0.1277 |
Brugia malayi | aspartic protease BmAsp-2, identical | 0.0364 | 0.0716 | 0.1277 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0036 | 0.0049 | 0.0049 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0364 | 0.0716 | 1 |
Plasmodium vivax | plasmepsin V, putative | 0.0364 | 0.0716 | 1 |
Plasmodium falciparum | plasmepsin VIII, putative | 0.0364 | 0.0716 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0049 | 0.0417 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0853 | 0.1708 | 0.1708 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0021 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0049 | 0.0049 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0161 | 0.0287 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0049 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.099 | 0.1987 | 0.3544 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0049 | 0.0417 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.0014 | 0.0025 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0049 | 0.0088 |
Echinococcus granulosus | tar DNA binding protein | 0.0129 | 0.0238 | 0.0424 |
Brugia malayi | hypothetical protein | 0.0364 | 0.0716 | 0.1277 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0161 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0017 | 0.003 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0129 | 0.0238 | 0.0424 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0049 | 0.0088 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.0031 | 0.0214 |
Plasmodium falciparum | plasmepsin IX | 0.0364 | 0.0716 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0468 | 0.0927 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0049 | 0.0417 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0048 | 0.0074 | 0.0131 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0049 | 0.0088 |
Echinococcus multilocularis | tar DNA binding protein | 0.0129 | 0.0238 | 0.0424 |
Onchocerca volvulus | 0.0036 | 0.0049 | 0.0207 | |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0077 | 0.0138 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0036 | 0.0049 | 0.0087 |
Schistosoma mansoni | acetylcholinesterase | 0.0468 | 0.0927 | 0.0927 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0036 | 0.0065 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.1152 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.0227 | 0.0227 |
Brugia malayi | Pre-SET motif family protein | 0.0209 | 0.04 | 0.0713 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.2771 | 0.5608 | 0.5608 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0161 | 0.0161 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0049 | 0.0417 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0468 | 0.0927 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0468 | 0.0927 | 0.0927 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0112 | 0.0204 | 0.0364 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0161 | 0.0287 |
Brugia malayi | Protein kinase domain containing protein | 0.0036 | 0.0049 | 0.0087 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0077 | 0.0138 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0048 | 0.0074 | 0.0684 |
Echinococcus granulosus | acetylcholinesterase | 0.2771 | 0.5608 | 1 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0017 | 0.003 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0036 | 0.0065 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0048 | 0.0074 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0031 | 0.2007 |
Brugia malayi | Carboxylesterase family protein | 0.0468 | 0.0927 | 0.1654 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0364 | 0.0716 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0049 | 0.0088 |
Loa Loa (eye worm) | carboxylesterase | 0.0468 | 0.0927 | 0.1654 |
Plasmodium falciparum | plasmepsin II | 0.0364 | 0.0716 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Brugia malayi | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0049 | 0.3735 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.1152 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0036 | 0.0282 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0045 | 0.0045 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0049 | 0.0417 |
Schistosoma mansoni | gliotactin | 0.0468 | 0.0927 | 0.0927 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0031 | 0.0055 |
Plasmodium vivax | aspartyl protease, putative | 0.0364 | 0.0716 | 1 |
Onchocerca volvulus | 0.0238 | 0.0459 | 0.4776 | |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1636 | 0.3301 | 0.5886 |
Loa Loa (eye worm) | hypothetical protein | 0.2771 | 0.5608 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0049 | 0.0417 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0008 | 0.0014 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.2338 | 0.4727 | 0.843 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0049 | 0.0188 |
Brugia malayi | Carboxylesterase family protein | 0.2771 | 0.5608 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.2771 | 0.5608 | 1 |
Plasmodium falciparum | plasmepsin III | 0.0364 | 0.0716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0049 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Echinococcus multilocularis | acetylcholinesterase | 0.2771 | 0.5608 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0008 | 0.0014 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0018 | 0.0033 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0353 | 0.0694 | 0.1237 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0021 | 0.0037 |
Onchocerca volvulus | 0.0468 | 0.0927 | 1 | |
Echinococcus granulosus | neuroligin | 0.0468 | 0.0927 | 0.1654 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0027 | 0.0031 | 0.0214 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0074 | 0.0132 |
Plasmodium falciparum | plasmepsin VI | 0.0364 | 0.0716 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0008 | 0.0014 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0468 | 0.0927 | 0.1654 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0133 | 0.0247 | 0.044 |
Echinococcus granulosus | neuropeptide s receptor | 0.0531 | 0.1055 | 0.1882 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.0161 | 0.0287 |
Plasmodium falciparum | plasmepsin IV | 0.0364 | 0.0716 | 1 |
Echinococcus multilocularis | protein dispatched 1 | 0.0055 | 0.0088 | 0.0156 |
Plasmodium vivax | aspartyl protease, putative | 0.0364 | 0.0716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0123 | 0.0227 | 0.0404 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0014 | 0.0038 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.0054 | 0.0097 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0011 | 0.0011 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0036 | 0.0049 | 0.0087 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0008 | 0.0014 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0036 | 0.0049 | 0.0087 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0468 | 0.0927 | 0.0927 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0788 | 0.1578 | 0.1578 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0031 | 0.0055 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0049 | 0.0049 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Brugia malayi | hypothetical protein | 0.0364 | 0.0716 | 0.1277 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0008 | 0.0014 |
Schistosoma mansoni | zinc finger protein | 0.0016 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0049 | 0.0088 |
Onchocerca volvulus | 0.0364 | 0.0716 | 0.7642 | |
Loa Loa (eye worm) | carboxylesterase | 0.2771 | 0.5608 | 1 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0125 | 0.0223 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0049 | 0.0417 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0036 | 0.0049 | 0.0087 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0129 | 0.0238 | 0.0424 |
Plasmodium vivax | plasmepsin IV, putative | 0.0364 | 0.0716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.0031 | 0.5134 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0125 | 0.5444 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0161 | 0.0302 | 0.0539 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0788 | 0.1578 | 0.2814 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0036 | 0.0049 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.2771 | 0.5608 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.2771 | 0.5608 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0027 | 0.0031 | 0.0214 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.1152 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.0017 | 0.5 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.1152 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 6.3 mg kg-1 | Effective dose required for writhing response in mouse after 20 minutes on sc administration | ChEMBL. | 7901416 |
ED50 (functional) | = 6.8 mg kg-1 | Effective dose required for writhing response in mouse after 20 minutes on ig administration | ChEMBL. | 7901416 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.