Species | Potential target | Known druggable target | Length | Alignment span | Identity |
---|---|---|---|---|---|
Trypanosoma brucei | DNA topoisomerase II beta, putative | mitochondrial DNA topoisomerase II, putative | 1231 aa | 1042 aa | 35.3 % |
Trypanosoma brucei | DNA topoisomerase II beta, putative | mitochondrial DNA topoisomerase II | 1236 aa | 1047 aa | 35.1 % |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0144 | 0.0089 | 0.2589 | |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.027 | 0.018 | 0.0427 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.001 | 0.0216 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0013 | 0.0309 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.001 | 0.0216 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0382 | 0.0261 | 0.9975 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0012 | 0.0267 |
Entamoeba histolytica | hypothetical protein | 0.0332 | 0.0224 | 0.8563 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0285 | 0.0191 | 0.0448 |
Brugia malayi | jmjC domain containing protein | 0.0095 | 0.0054 | 0.0914 |
Mycobacterium tuberculosis | Conserved protein | 0.0144 | 0.0089 | 0.0198 |
Onchocerca volvulus | 0.0101 | 0.0058 | 0.1683 | |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0297 | 0.0199 | 0.0199 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0053 | 0.0023 | 0.0023 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0013 | 0.033 |
Mycobacterium ulcerans | DNA gyrase subunit B | 0.0197 | 0.0127 | 0.0288 |
Schistosoma mansoni | hypothetical protein | 0.0818 | 0.0575 | 0.0575 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Brugia malayi | MH2 domain containing protein | 0.0057 | 0.0027 | 0.045 |
Brugia malayi | MH1 domain containing protein | 0.0057 | 0.0027 | 0.045 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0383 | 0.0261 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0023 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0007 | 0.0124 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0025 | 0.0003 | 0.0054 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0053 | 0.0023 | 0.0676 |
Onchocerca volvulus | Cathepsin L homolog | 0.0101 | 0.0058 | 0.1683 |
Brugia malayi | Cathepsin L-like precursor | 0.0033 | 0.0009 | 0.0157 |
Schistosoma mansoni | smad | 0.0026 | 0.0004 | 0.0004 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.001 | 0.0216 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0144 | 0.0089 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0009 | 0.0157 |
Entamoeba histolytica | hypothetical protein | 0.0332 | 0.0224 | 0.8563 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0383 | 0.0261 | 1 |
Echinococcus multilocularis | geminin | 0.0534 | 0.037 | 0.037 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0135 | 0.0082 | 0.1394 |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 0.0191 | 0.3232 |
Brugia malayi | Pre-SET motif family protein | 0.0437 | 0.03 | 0.5073 |
Schistosoma mansoni | hypothetical protein | 0.0097 | 0.0055 | 0.0055 |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Brugia malayi | Cathepsin L-like precursor | 0.0101 | 0.0058 | 0.0977 |
Brugia malayi | tailless protein | 0.0025 | 0.0003 | 0.0054 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0066 | 0.0033 | 0.0033 |
Echinococcus granulosus | expressed protein | 0.0034 | 0.001 | 0.001 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0053 | 0.0023 | 0.0023 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0053 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.0197 | 0.0127 | 0.3305 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0081 | 0.0044 | 0.0044 |
Onchocerca volvulus | 0.0101 | 0.0058 | 0.1683 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0052 | 0.0023 | 0.0712 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0053 | 0.0023 | 0.0023 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.0035 | 0.0957 |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 0.0191 | 0.3232 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0112 | 0.0066 | 0.2273 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0033 | 0.0009 | 0.0157 |
Echinococcus granulosus | GPCR family 2 | 0.016 | 0.0101 | 0.0101 |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0144 | 0.0089 | 0.1503 |
Plasmodium vivax | vivapain-1 | 0.0052 | 0.0023 | 0.0588 |
Brugia malayi | intermediate filament protein | 0.0135 | 0.0082 | 0.1394 |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Loa Loa (eye worm) | hypothetical protein | 0.0554 | 0.0385 | 0.6509 |
Echinococcus granulosus | lamin | 0.0135 | 0.0082 | 0.0082 |
Schistosoma mansoni | lamin | 0.0135 | 0.0082 | 0.0082 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.031 | 0.0208 | 0.0208 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0033 | 0.0009 | 0.0299 |
Schistosoma mansoni | lamin | 0.0135 | 0.0082 | 0.0082 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0052 | 0.0023 | 0.0825 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0112 | 0.0066 | 0.0141 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0006 | 0.0052 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0383 | 0.0261 | 1 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0112 | 0.0066 | 0.0134 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0025 | 0.0003 | 0.0093 |
Leishmania major | hypothetical protein, conserved | 0.0144 | 0.0089 | 0.329 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0053 | 0.0023 | 0.0392 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0052 | 0.0023 | 0.0712 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0005 | 0.009 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0112 | 0.0066 | 0.0134 |
Schistosoma mansoni | cathepsin s | 0.0033 | 0.0009 | 0.0009 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0285 | 0.0191 | 0.4419 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0228 | 0.015 | 0.4362 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0052 | 0.0023 | 0.0712 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0065 | 0.0032 | 0.0032 |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0013 | 0.0013 |
Onchocerca volvulus | 0.0067 | 0.0034 | 0.0985 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0101 | 0.0058 | 0.1501 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0053 | 0.0023 | 0.0392 |
Mycobacterium ulcerans | hypothetical protein | 0.0144 | 0.0089 | 0.0191 |
Plasmodium falciparum | DNA gyrase subunit A | 0.0073 | 0.0038 | 0.0978 |
Echinococcus granulosus | zinc finger protein | 0.0023 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0005 | 0.009 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0112 | 0.0066 | 0.1859 |
Schistosoma mansoni | intermediate filament proteins | 0.0135 | 0.0082 | 0.0082 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0101 | 0.0058 | 0.0058 |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0382 | 0.0261 | 1 |
Brugia malayi | chromobox protein homolog 3 | 0.0039 | 0.0013 | 0.0227 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.0035 | 0.0957 |
Trichomonas vaginalis | rotamase, putative | 0.0034 | 0.001 | 0.0194 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0346 | 0.0234 | 0.3966 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0004 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0019 | 0.0317 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0112 | 0.0066 | 0.0066 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0003 | 0.0014 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0101 | 0.0058 | 0.0977 |
Brugia malayi | beta-lactamase family protein | 0.0144 | 0.0089 | 0.1503 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0554 | 0.0385 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0053 | 0.0023 | 0.0392 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0319 | 0.0215 | 0.8216 |
Echinococcus granulosus | cysteine protease | 0.0052 | 0.0023 | 0.0023 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0112 | 0.0066 | 0.0141 |
Entamoeba histolytica | cysteine protease, putative | 0.0101 | 0.0058 | 0.1939 |
Onchocerca volvulus | 0.0053 | 0.0023 | 0.0676 | |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.027 | 0.018 | 0.0427 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0053 | 0.0023 | 0.0023 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0319 | 0.0215 | 0.8238 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0053 | 0.0023 | 0.0392 |
Mycobacterium leprae | Probable lipase LipE | 0.0144 | 0.0089 | 0.0198 |
Schistosoma mansoni | hypothetical protein | 0.016 | 0.0101 | 0.0101 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0114 | 0.0067 | 0.1651 |
Plasmodium vivax | DNA gyrase subunit A, putative | 0.0073 | 0.0038 | 0.0978 |
Toxoplasma gondii | hypothetical protein | 0.0191 | 0.0123 | 0.3118 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0918 | 0.0647 | 0.1601 |
Trichomonas vaginalis | glutaminase, putative | 0.033 | 0.0223 | 0.6473 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0053 | 0.0023 | 0.0392 |
Schistosoma mansoni | glutaminase | 0.033 | 0.0223 | 0.0223 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0382 | 0.0261 | 0.0623 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0013 | 0.0291 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0053 | 0.0023 | 0.0392 |
Leishmania major | cathepsin L-like protease | 0.0383 | 0.0261 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0057 | 0.0027 | 0.045 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0554 | 0.0385 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.016 | 0.0101 | 0.1703 |
Brugia malayi | beta-lactamase family protein | 0.0144 | 0.0089 | 0.1503 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0034 | 0.001 | 0.0161 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0026 | 0.0004 | 0.0064 |
Plasmodium vivax | unspecified product | 0.0033 | 0.0009 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0506 | 0.035 | 0.5917 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0112 | 0.0066 | 0.2406 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0013 | 0.0448 |
Mycobacterium leprae | conserved hypothetical protein | 0.0144 | 0.0089 | 0.0198 |
Brugia malayi | ecdysone receptor | 0.0025 | 0.0003 | 0.0054 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0047 | 0.0019 | 0.0393 |
Brugia malayi | Cathepsin L-like precursor | 0.0067 | 0.0034 | 0.0572 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0383 | 0.0261 | 1 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0379 | 0.0258 | 0.9888 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0005 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0009 | 0.0157 |
Plasmodium falciparum | DNA gyrase subunit B | 0.0197 | 0.0127 | 0.3305 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0066 | 0.0033 | 0.0033 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.016 | 0.0101 | 0.0101 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0066 | 0.0033 | 0.0033 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0028 | 0.0005 | 0.0005 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0011 | 0.0011 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0053 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0053 | 0.0023 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0034 | 0.0572 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0064 | 0.0031 | 0.0707 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.015 | 0.2536 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0382 | 0.0261 | 0.063 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0057 | 0.0027 | 0.045 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0144 | 0.0089 | 0.2526 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0112 | 0.0066 | 0.0141 |
Onchocerca volvulus | 0.0031 | 0.0007 | 0.0214 | |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0338 | 0.0229 | 0.0229 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0101 | 0.0058 | 0.0058 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.0013 | 0.0013 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0012 | 0.0267 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0363 | 0.0247 | 0.0596 |
Mycobacterium ulcerans | lipase LipD | 0.0144 | 0.0089 | 0.0191 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0319 | 0.0215 | 0.8238 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0025 | 0.0003 | 0.0003 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0047 | 0.0019 | 0.0019 |
Mycobacterium tuberculosis | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0073 | 0.0038 | 0.007 |
Echinococcus multilocularis | microtubule associated protein 2 | 1.3898 | 1 | 1 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0191 | 0.0123 | 0.0284 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0332 | 0.0224 | 0.0224 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0382 | 0.0261 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0058 | 0.0027 | 0.0037 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0019 | 0.0019 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0312 | 0.021 | 0.8011 |
Brugia malayi | glutaminase DH11.1 | 0.033 | 0.0223 | 0.3775 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0057 | 0.0027 | 0.0027 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0047 | 0.0019 | 0.0393 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0053 | 0.0023 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.015 | 0.2536 |
Leishmania major | cathepsin L-like protease | 0.0101 | 0.0058 | 0.2079 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0058 | 0.0027 | 0.0896 |
Toxoplasma gondii | hypothetical protein | 0.005 | 0.0022 | 0.0453 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0383 | 0.0261 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0383 | 0.0261 | 1 |
Echinococcus granulosus | Smad4 | 0.0057 | 0.0027 | 0.0027 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0554 | 0.0385 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0382 | 0.0261 | 0.9975 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0338 | 0.0229 | 0.0229 |
Schistosoma mansoni | jumonji domain containing protein | 0.0076 | 0.004 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0019 | 0.0324 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0058 | 0.0027 | 0.0391 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.0013 | 0.0291 |
Onchocerca volvulus | 0.0112 | 0.0066 | 0.1928 | |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0006 | 0.0164 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0006 | 0.0006 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0112 | 0.0066 | 0.2498 |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 0.0191 | 0.3232 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0035 | 0.001 | 0.0156 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0338 | 0.0229 | 0.594 |
Brugia malayi | AMP-binding enzyme family protein | 0.0112 | 0.0066 | 0.1119 |
Plasmodium vivax | unspecified product | 0.0052 | 0.0023 | 0.0588 |
Schistosoma mansoni | nuclear hormone receptor | 0.0025 | 0.0003 | 0.0003 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0191 | 0.0123 | 0.3195 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0057 | 0.0027 | 0.0027 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0191 | 0.0123 | 0.2675 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0053 | 0.0023 | 0.0023 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0006 | 0.0006 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0053 | 0.0023 | 0.0023 |
Brugia malayi | AMP-binding enzyme family protein | 0.0112 | 0.0066 | 0.1119 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0058 | 0.0027 | 0.0711 |
Mycobacterium leprae | Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) | 0.0088 | 0.0049 | 0.0097 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.004 | 0.0014 | 0.0014 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0148 | 0.0092 | 0.3482 |
Onchocerca volvulus | 0.0112 | 0.0066 | 0.1928 | |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0112 | 0.0066 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 0.0191 | 0.3232 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0285 | 0.0191 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0032 | 0.0544 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0026 | 0.0004 | 0.0004 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0012 | 0.0267 |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0003 | 0.0014 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0112 | 0.0066 | 0.2498 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0052 | 0.0023 | 0.058 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0112 | 0.0066 | 0.0134 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0383 | 0.0261 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0025 | 0.0003 | 0.0003 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0064 | 0.0032 | 0.0032 |
Echinococcus granulosus | geminin | 0.0534 | 0.037 | 0.037 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0112 | 0.0066 | 0.0134 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0338 | 0.0229 | 0.5894 |
Schistosoma mansoni | coup transcription factor | 0.0053 | 0.0023 | 0.0023 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0058 | 0.0027 | 0.1004 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0005 | 0.009 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0029 | 0.0485 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0057 | 0.0027 | 0.045 |
Mycobacterium tuberculosis | Integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase) | 0.5556 | 0.3989 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0101 | 0.0058 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0019 | 0.0317 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0382 | 0.0261 | 0.0623 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0006 | 0.0164 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0554 | 0.0385 | 1 |
Mycobacterium leprae | Probable integral membrane indolylacetylinositol arabinosyltransferase EmbB (arabinosylindolylacetylinositol synthase) | 0.5556 | 0.3989 | 1 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0033 | 0.0009 | 0.0121 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0015 | 0.0015 |
Mycobacterium ulcerans | hypothetical protein | 0.0382 | 0.0261 | 0.0623 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.0035 | 0.0035 |
Brugia malayi | beta-lactamase | 0.0144 | 0.0089 | 0.1503 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0005 | 0.0068 |
Onchocerca volvulus | 0.0116 | 0.0069 | 0.2016 | |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0052 | 0.0023 | 0.0544 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0101 | 0.0058 | 0.0058 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0144 | 0.0089 | 0.1503 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.001 | 0.0216 |
Leishmania major | cathepsin L-like protease | 0.0101 | 0.0058 | 0.2079 |
Toxoplasma gondii | propionate-CoA ligase | 0.0112 | 0.0066 | 0.1625 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0013 | 0.033 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0066 | 0.0033 | 0.1121 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0112 | 0.0066 | 0.1119 |
Brugia malayi | nuclear receptor NHR-88 | 0.0053 | 0.0023 | 0.0392 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0013 | 0.0309 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0112 | 0.0066 | 0.0134 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0019 | 0.0565 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0382 | 0.0261 | 0.0623 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.0035 | 0.0035 |
Brugia malayi | Cathepsin L-like precursor | 0.0101 | 0.0058 | 0.0977 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0301 | 0.0202 | 0.7701 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0144 | 0.0089 | 0.0198 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0058 | 0.0027 | 0.0027 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0058 | 0.0027 | 0.0896 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0554 | 0.0385 | 0.0942 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.006 | 0.0029 | 0.0029 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0057 | 0.0027 | 0.0027 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0026 | 0.0004 | 0.0004 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0554 | 0.0385 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0053 | 0.0023 | 0.0392 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0006 | 0.0184 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0013 | 0.0291 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0019 | 0.0468 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0144 | 0.0089 | 0.0198 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0052 | 0.0023 | 0.0023 |
Brugia malayi | AMP-binding enzyme family protein | 0.0112 | 0.0066 | 0.1119 |
Onchocerca volvulus | 0.0112 | 0.0066 | 0.1928 | |
Onchocerca volvulus | 0.0135 | 0.0082 | 0.2401 | |
Schistosoma mansoni | hypothetical protein | 0.0534 | 0.037 | 0.037 |
Echinococcus granulosus | dnaJ subfamily B | 0.0818 | 0.0575 | 0.0575 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0097 | 0.0055 | 0.093 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0026 | 0.0004 | 0.0004 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0101 | 0.0058 | 0.0058 |
Echinococcus granulosus | FTZ F1 alpha | 0.0053 | 0.0023 | 0.0023 |
Brugia malayi | Cytochrome P450 family protein | 0.005 | 0.0022 | 0.0366 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.001 | 0.0216 |
Echinococcus granulosus | cathepsin l1 | 0.0101 | 0.0058 | 0.0058 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0053 | 0.0023 | 0.0676 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0382 | 0.0261 | 1 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0363 | 0.0247 | 0.0247 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0053 | 0.0023 | 0.0392 |
Mycobacterium tuberculosis | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0197 | 0.0127 | 0.0295 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0112 | 0.0066 | 0.0134 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0312 | 0.021 | 0.8011 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0003 | 0.0015 |
Onchocerca volvulus | 0.0097 | 0.0055 | 0.1602 | |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Mycobacterium leprae | Probable integral membrane indolylacetylinositol arabinosyltransferase EmbA (arabinosylindolylacetylinositol synthase) | 0.5556 | 0.3989 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0028 | 0.0005 | 0.009 |
Brugia malayi | AMP-binding enzyme family protein | 0.0382 | 0.0261 | 0.4409 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0034 | 0.0572 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0053 | 0.0023 | 0.0023 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0382 | 0.0261 | 0.0623 |
Mycobacterium tuberculosis | Integral membrane indolylacetylinositol arabinosyltransferase EmbB (arabinosylindolylacetylinositol synthase) | 0.5556 | 0.3989 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0144 | 0.0089 | 0.2526 |
Mycobacterium ulcerans | integral membrane indolylacetylinositol arabinosyltransferase EmbC | 0.5556 | 0.3989 | 1 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0112 | 0.0066 | 0.2406 |
Schistosoma mansoni | hypothetical protein | 0.016 | 0.0101 | 0.0101 |
Mycobacterium ulcerans | hypothetical protein | 0.0164 | 0.0104 | 0.0229 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0003 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0144 | 0.0089 | 0.2526 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0053 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0053 | 0.0023 | 0.0392 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0112 | 0.0066 | 0.0134 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0197 | 0.0127 | 0.3229 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0818 | 0.0575 | 0.0575 |
Loa Loa (eye worm) | Smad1 | 0.0057 | 0.0027 | 0.045 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0101 | 0.0058 | 0.0058 |
Schistosoma mansoni | ap endonuclease | 0.0058 | 0.0027 | 0.0027 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0112 | 0.0066 | 0.0141 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0025 | 0.0003 | 0.0054 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0053 | 0.0023 | 0.0023 |
Giardia lamblia | GTOR | 0.0047 | 0.0019 | 0.0598 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0112 | 0.0066 | 0.0134 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0112 | 0.0066 | 0.0141 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0025 | 0.0003 | 0.0003 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0003 | 0.0014 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0101 | 0.0058 | 0.1501 |
Onchocerca volvulus | 0.0323 | 0.0218 | 0.6346 | |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0112 | 0.0066 | 0.0066 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0026 | 0.0004 | 0.0004 |
Schistosoma mansoni | Smad4 | 0.0026 | 0.0004 | 0.0004 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0554 | 0.0385 | 0.0385 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0112 | 0.0066 | 0.1119 |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0005 | 0.009 |
Echinococcus multilocularis | smad | 0.0057 | 0.0027 | 0.0027 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0019 | 0.0679 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0338 | 0.0229 | 0.6632 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0025 | 0.0003 | 0.0003 |
Leishmania major | cysteine peptidase A (CPA) | 0.0101 | 0.0058 | 0.2079 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0066 | 0.0033 | 0.0033 |
Leishmania major | cathepsin L-like protease | 0.0101 | 0.0058 | 0.2079 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0053 | 0.0023 | 0.0392 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0379 | 0.0258 | 0.9886 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0026 | 0.0004 | 0.0004 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0506 | 0.035 | 0.5917 |
Echinococcus multilocularis | peregrin | 0.0032 | 0.0008 | 0.0008 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0033 | 0.0009 | 0.0157 |
Loa Loa (eye worm) | nuclear factor I | 0.0032 | 0.0008 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0382 | 0.0261 | 0.4409 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0004 | 0.0113 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0228 | 0.015 | 0.4362 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0112 | 0.0066 | 0.0141 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0047 | 0.0019 | 0.0565 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0382 | 0.0261 | 0.0623 |
Schistosoma mansoni | rotamase | 0.0034 | 0.001 | 0.001 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0001 | 0.001 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0025 | 0.0003 | 0.0054 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0025 | 0.0003 | 0.0003 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0052 | 0.0023 | 0.0544 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0053 | 0.0023 | 0.0023 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase, topoisomerase II, B subunit, GyrB | 0.0197 | 0.0127 | 0.3074 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0257 | 0.0171 | 0.0171 |
Brugia malayi | AMP-binding enzyme family protein | 0.0112 | 0.0066 | 0.1119 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0144 | 0.0089 | 0.0089 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0506 | 0.035 | 0.5917 |
Schistosoma mansoni | nuclear hormone receptor | 0.0053 | 0.0023 | 0.0023 |
Treponema pallidum | DNA gyrase, subunit B (gyrB) | 0.0197 | 0.0127 | 0.2793 |
Schistosoma mansoni | microtubule-associated protein tau | 1.3898 | 1 | 1 |
Onchocerca volvulus | 0.0101 | 0.0058 | 0.1683 | |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0047 | 0.0019 | 0.0679 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.004 | 0.0014 | 0.0014 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Schistosoma mansoni | smad | 0.0057 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0379 | 0.0258 | 0.9886 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0009 | 0.018 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0112 | 0.0066 | 0.0141 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0008 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.0082 | 0.1394 |
Brugia malayi | MH2 domain containing protein | 0.0026 | 0.0004 | 0.0064 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0058 | 0.0027 | 0.0896 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0382 | 0.0261 | 0.9975 |
Schistosoma mansoni | smad1 5 8 and | 0.0057 | 0.0027 | 0.0027 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0004 | 0.0073 |
Schistosoma mansoni | smad1 5 8 and | 0.0057 | 0.0027 | 0.0027 |
Brugia malayi | nuclear receptor NHR-88 | 0.0025 | 0.0003 | 0.0054 |
Brugia malayi | nuclear hormone receptor | 0.0053 | 0.0023 | 0.0392 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0053 | 0.0023 | 0.0023 |
Brugia malayi | AMP-binding enzyme family protein | 0.0382 | 0.0261 | 0.4409 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0025 | 0.0003 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0008 | 0.0138 |
Loa Loa (eye worm) | fibroinase | 0.0101 | 0.0058 | 0.0977 |
Echinococcus multilocularis | musashi | 0.0135 | 0.0082 | 0.0082 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0841 | 0.0591 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0053 | 0.0023 | 0.0392 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0052 | 0.0023 | 0.0544 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0025 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0089 | 0.1503 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0026 | 0.0004 | 0.0004 |
Brugia malayi | Heterochromatin protein 1 | 0.007 | 0.0035 | 0.06 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0067 | 0.0034 | 0.0572 |
Loa Loa (eye worm) | intermediate filament protein | 0.0135 | 0.0082 | 0.1394 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0382 | 0.0261 | 0.063 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0044 | 0.0741 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.0035 | 0.0035 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0089 | 0.1503 |
Leishmania major | DNA topoisomerase ii | 0.0319 | 0.0215 | 0.8216 |
Trypanosoma cruzi | cysteine protease, putative | 0.0052 | 0.0023 | 0.0712 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0144 | 0.0089 | 0.0089 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0058 | 0.0027 | 0.0711 |
Brugia malayi | hypothetical protein | 0.0323 | 0.0218 | 0.3684 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0005 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0323 | 0.0218 | 0.3684 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.027 | 0.018 | 0.0427 |
Loa Loa (eye worm) | hypothetical protein | 0.0346 | 0.0234 | 0.3966 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0021 | 0.036 |
Echinococcus multilocularis | lamin | 0.0135 | 0.0082 | 0.0082 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.027 | 0.018 | 0.0427 |
Onchocerca volvulus | 0.0101 | 0.0058 | 0.1683 | |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0112 | 0.0066 | 0.2406 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.016 | 0.0101 | 0.1703 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0112 | 0.0066 | 0.0134 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0025 | 0.0003 | 0.0003 |
Echinococcus multilocularis | cpg binding protein | 0.0063 | 0.003 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0034 | 0.0572 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0089 | 0.1503 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0053 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0474 | 0.0327 | 0.553 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0191 | 0.0123 | 0.3195 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0312 | 0.021 | 0.8011 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0058 | 0.0027 | 0.1006 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0044 | 0.0017 | 0.049 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0006 | 0.0052 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.0035 | 0.0035 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0013 | 0.033 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0144 | 0.0089 | 0.329 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0053 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0028 | 0.0005 | 0.009 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0058 | 0.0027 | 0.0027 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.0016 | 0.0454 |
Schistosoma mansoni | hypothetical protein | 0.0257 | 0.0171 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0066 | 0.1119 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0025 | 0.0003 | 0.0054 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0554 | 0.0385 | 0.0936 |
Onchocerca volvulus | 0.0101 | 0.0058 | 0.1683 | |
Echinococcus multilocularis | cathepsin L | 0.0052 | 0.0023 | 0.0023 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.001 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Leishmania major | cathepsin L-like protease | 0.0383 | 0.0261 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0382 | 0.0261 | 0.4409 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0053 | 0.0023 | 0.0023 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0004 | 0.0113 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0052 | 0.0023 | 0.0544 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0197 | 0.0127 | 0.2579 |
Brugia malayi | Bromodomain containing protein | 0.008 | 0.0043 | 0.0729 |
Schistosoma mansoni | thyroid hormone receptor | 0.031 | 0.0208 | 0.0208 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0038 | 0.0013 | 0.0154 |
Brugia malayi | Probable ClpP-like protease | 0.0554 | 0.0385 | 0.6509 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0023 | 0.0392 |
Echinococcus multilocularis | zinc finger protein | 0.0023 | 0.0002 | 0.0002 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0383 | 0.0261 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0053 | 0.0023 | 0.0023 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0312 | 0.021 | 0.8035 |
Onchocerca volvulus | Cathepsin L homolog | 0.0101 | 0.0058 | 0.1683 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0144 | 0.0089 | 0.2526 |
Brugia malayi | Smad1 | 0.0057 | 0.0027 | 0.045 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0053 | 0.0023 | 0.0392 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0338 | 0.0229 | 0.3867 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0053 | 0.0023 | 0.0023 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0025 | 0.0003 | 0.0054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0053 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0023 | 0.0392 |
Mycobacterium tuberculosis | Conserved protein | 0.0144 | 0.0089 | 0.0198 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0124 | 0.0075 | 0.0075 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0028 | 0.0005 | 0.0005 |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0052 | 0.0023 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0006 | 0.0107 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0026 | 0.0004 | 0.0064 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0006 | 0.0006 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0026 | 0.0004 | 0.0004 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0066 | 0.0033 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0064 |
Brugia malayi | nuclear hormone receptor | 0.0025 | 0.0003 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0066 | 0.1119 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0052 | 0.0023 | 0.0383 |
Mycobacterium ulcerans | DNA gyrase subunit A | 0.0073 | 0.0038 | 0.0062 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0135 | 0.0082 | 0.1394 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase subunit A | 0.0073 | 0.0038 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0047 | 0.0019 | 0.0319 |
Schistosoma mansoni | ap endonuclease | 0.0058 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | cysteine protease | 0.0101 | 0.0058 | 0.0977 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0156 | 0.0097 | 0.1721 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0012 | 0.0012 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.016 | 0.0101 | 0.0101 |
Schistosoma mansoni | cpg binding protein | 0.0063 | 0.003 | 0.003 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0112 | 0.0066 | 0.0141 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0112 | 0.0066 | 0.0066 |
Leishmania major | pantothenate kinase subunit, putative | 0.0027 | 0.0005 | 0.0028 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0053 | 0.0023 | 0.0392 |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0144 | 0.0089 | 0.0198 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.016 | 0.0101 | 0.0101 |
Brugia malayi | Cathepsin L-like precursor | 0.0101 | 0.0058 | 0.0977 |
Brugia malayi | CXXC zinc finger family protein | 0.0057 | 0.0027 | 0.0452 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Brugia malayi | Probable DNA topoisomerase II | 0.0338 | 0.0229 | 0.3867 |
Entamoeba histolytica | hypothetical protein | 0.0332 | 0.0224 | 0.8563 |
Brugia malayi | ecdysteroid receptor | 0.0053 | 0.0023 | 0.0392 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0112 | 0.0066 | 0.1625 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0383 | 0.0261 | 1 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0338 | 0.0229 | 0.594 |
Giardia lamblia | DNA topoisomerase II | 0.032 | 0.0216 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0382 | 0.0261 | 0.0623 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0089 | 0.1503 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0006 | 0.0103 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0052 | 0.0023 | 0.0544 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0144 | 0.0089 | 0.0191 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0012 | 0.0012 |
Brugia malayi | Pre-SET motif family protein | 0.0064 | 0.0031 | 0.0528 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0112 | 0.0066 | 0.2406 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0044 | 0.0017 | 0.0606 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0053 | 0.0023 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0023 | 0.0392 |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Mycobacterium ulcerans | integral membrane indolylacetylinositol arabinosyltransferase EmbB | 0.5556 | 0.3989 | 1 |
Mycobacterium leprae | Probable integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase) | 0.5556 | 0.3989 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Brugia malayi | Inositol-1 | 0.0038 | 0.0013 | 0.0217 |
Echinococcus granulosus | lamin dm0 | 0.0135 | 0.0082 | 0.0082 |
Brugia malayi | Latrophilin receptor protein 2 | 0.016 | 0.0101 | 0.1703 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0332 | 0.0224 | 0.0224 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0065 | 0.0032 | 0.0032 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0112 | 0.0066 | 0.0134 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0005 | 0.009 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0144 | 0.0089 | 0.0198 |
Brugia malayi | hypothetical protein | 0.0474 | 0.0327 | 0.553 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0058 | 0.0027 | 0.0044 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0053 | 0.0023 | 0.0023 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0028 | 0.0005 | 0.0005 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0025 | 0.0003 | 0.0003 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0554 | 0.0385 | 0.0385 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0053 | 0.0023 | 0.0392 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0144 | 0.0089 | 0.2526 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0144 | 0.0089 | 0.0198 |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0101 | 0.0058 | 0.1939 |
Plasmodium vivax | SET domain protein, putative | 0.0064 | 0.0031 | 0.0811 |
Onchocerca volvulus | 0.0025 | 0.0003 | 0.0093 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0064 | 0.0032 | 0.0032 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0383 | 0.0261 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0338 | 0.0229 | 0.3867 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0016 | 0.0372 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.0101 | 0.1703 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0474 | 0.0327 | 0.0327 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0112 | 0.0066 | 0.1119 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0058 | 0.0977 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0006 | 0.0107 |
Onchocerca volvulus | 0.0101 | 0.0058 | 0.1683 | |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0382 | 0.0261 | 0.063 |
Brugia malayi | nuclear receptor RXR | 0.0028 | 0.0005 | 0.009 |
Echinococcus multilocularis | cysteine protease | 0.0101 | 0.0058 | 0.0058 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0052 | 0.0023 | 0.0544 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0095 | 0.0054 | 0.0054 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0363 | 0.0247 | 0.0596 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0057 | 0.0027 | 0.0027 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0112 | 0.0066 | 0.1625 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0053 | 0.0024 | 0.076 |
Echinococcus multilocularis | Smad4 | 0.0057 | 0.0027 | 0.0027 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0053 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0034 | 0.001 | 0.0161 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0554 | 0.0385 | 1 |
Mycobacterium ulcerans | glutaminase | 0.033 | 0.0223 | 0.0529 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0112 | 0.0066 | 0.0141 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0053 | 0.0023 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0084 | 0.1425 |
Loa Loa (eye worm) | oxidoreductase | 0.0112 | 0.0066 | 0.1119 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0228 | 0.015 | 0.4362 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.0033 | 0.0051 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0144 | 0.0089 | 0.3371 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0019 | 0.0468 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0023 | 0.0392 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0025 | 0.0003 | 0.0003 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0363 | 0.0247 | 0.0247 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0101 | 0.0058 | 0.0058 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0101 | 0.0058 | 0.0977 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0112 | 0.0066 | 0.0134 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0112 | 0.0066 | 0.2406 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Onchocerca volvulus | 0.0135 | 0.0082 | 0.2401 | |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0026 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0073 |
Brugia malayi | Cathepsin L-like precursor | 0.0101 | 0.0058 | 0.0977 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0058 | 0.0027 | 0.0718 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0067 | 0.0034 | 0.0034 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.0013 | 0.0223 |
Leishmania major | cathepsin L-like protease | 0.0101 | 0.0058 | 0.2079 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0058 | 0.0027 | 0.0463 |
Onchocerca volvulus | 0.0144 | 0.0089 | 0.2589 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0064 | 0.0031 | 0.0031 |
Schistosoma mansoni | cpg binding protein | 0.0063 | 0.003 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0023 | 0.0392 |
Brugia malayi | cathepsin L-like precursor | 0.0067 | 0.0034 | 0.0572 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0039 | 0.0013 | 0.0391 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0081 | 0.0044 | 0.0044 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0025 | 0.0003 | 0.0093 |
Schistosoma mansoni | nuclear receptor | 0.0025 | 0.0003 | 0.0003 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0554 | 0.0385 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.001 | 0.0194 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0052 | 0.0023 | 0.0825 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0067 | 0.0034 | 0.0988 |
Trichomonas vaginalis | set domain proteins, putative | 0.0497 | 0.0343 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0144 | 0.0089 | 0.329 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.0009 | 0.0177 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0383 | 0.0261 | 1 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0025 | 0.0003 | 0.0003 |
Schistosoma mansoni | Smad4 | 0.0057 | 0.0027 | 0.0027 |
Leishmania major | mitochondrial DNA topoisomerase II | 0.0379 | 0.0258 | 0.9886 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0112 | 0.0066 | 0.2406 |
Brugia malayi | MH1 domain containing protein | 0.0032 | 0.0008 | 0.0138 |
Trichomonas vaginalis | esterase, putative | 0.0144 | 0.0089 | 0.2526 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.016 | 0.0101 | 0.0101 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0112 | 0.0066 | 0.0134 |
Brugia malayi | MH1 domain containing protein | 0.0032 | 0.0008 | 0.0138 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0112 | 0.0066 | 0.0141 |
Brugia malayi | MH2 domain containing protein | 0.0057 | 0.0027 | 0.045 |
Toxoplasma gondii | ABC1 family protein | 0.0144 | 0.0089 | 0.2222 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0052 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.003 | 0.0514 |
Onchocerca volvulus | 0.0057 | 0.0027 | 0.0779 | |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0144 | 0.0089 | 0.0191 |
Toxoplasma gondii | cathepsin CPL | 0.0101 | 0.0058 | 0.1404 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0026 | 0.0004 | 0.011 |
Brugia malayi | steroid hormone receptor | 0.0053 | 0.0023 | 0.0392 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0057 | 0.0027 | 0.0452 |
Leishmania major | cathepsin L-like protease | 0.0101 | 0.0058 | 0.2079 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0034 | 0.0908 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0053 | 0.0023 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0053 | 0.0023 | 0.0392 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0112 | 0.0066 | 0.0141 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0257 | 0.0171 | 0.0171 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0052 | 0.0023 | 0.0023 |
Echinococcus multilocularis | GPCR, family 2 | 0.016 | 0.0101 | 0.0101 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0112 | 0.0066 | 0.0134 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0506 | 0.035 | 0.5917 |
Echinococcus granulosus | cpg binding protein | 0.0063 | 0.003 | 0.003 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0052 | 0.0023 | 0.0023 |
Onchocerca volvulus | 0.0382 | 0.0261 | 0.7594 | |
Treponema pallidum | DNA gyrase, subunit A (gyrA) | 0.0073 | 0.0038 | 0.0288 |
Trypanosoma cruzi | pantothenate kinase subunit, putative | 0.0027 | 0.0005 | 0.0028 |
Echinococcus multilocularis | tumor protein p63 | 0.203 | 0.1448 | 0.1448 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0089 | 0.1503 |
Plasmodium vivax | hypothetical protein, conserved | 0.0144 | 0.0089 | 0.2309 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0014 | 0.0231 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0148 | 0.0092 | 0.3401 |
Schistosoma mansoni | hypothetical protein | 0.016 | 0.0101 | 0.0101 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0112 | 0.0066 | 0.0141 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0033 | 0.0009 | 0.0192 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0031 | 0.0008 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0013 | 0.0227 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0014 | 0.0324 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0144 | 0.0089 | 0.0198 |
Echinococcus granulosus | peregrin | 0.0032 | 0.0008 | 0.0008 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0554 | 0.0385 | 0.0936 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0025 | 0.0003 | 0.0054 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0025 | 0.0003 | 0.0003 |
Schistosoma mansoni | smad1 5 8 and | 0.0057 | 0.0027 | 0.0027 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0382 | 0.0261 | 0.063 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0064 | 0.0031 | 0.0031 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0383 | 0.0261 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0014 | 0.023 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0052 | 0.0023 | 0.0588 |
Mycobacterium tuberculosis | Conserved protein | 0.0144 | 0.0089 | 0.0198 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0474 | 0.0327 | 0.0327 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0033 | 0.0009 | 0.0157 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0033 | 0.0009 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0033 | 0.0009 | 0.018 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0053 | 0.0023 | 0.0023 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0081 | 0.0044 | 0.0044 |
Brugia malayi | MH2 domain containing protein | 0.0841 | 0.0591 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0025 | 0.0003 | 0.0003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0383 | 0.0261 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0332 | 0.0224 | 0.8563 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0009 | 0.018 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0979 | 0.0691 | 0.0691 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0005 | 0.0072 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.0033 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0038 | 0.0635 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0112 | 0.0066 | 0.2406 |
Echinococcus granulosus | tumor protein p63 | 0.203 | 0.1448 | 0.1448 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0044 | 0.0017 | 0.049 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.0035 | 0.0035 |
Mycobacterium ulcerans | integral membrane indolylacetylinositol arabinosyltransferase EmbA | 0.5556 | 0.3989 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0101 | 0.0058 | 0.0977 |
Toxoplasma gondii | DNA gyrase/topoisomerase IV, A subunit domain-containing protein | 0.0073 | 0.0038 | 0.0875 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Schistosoma mansoni | hypothetical protein | 0.0534 | 0.037 | 0.037 |
Brugia malayi | nuclear receptor RXR | 0.0025 | 0.0003 | 0.0054 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0338 | 0.0229 | 0.3867 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0437 | 0.03 | 0.5073 |
Echinococcus granulosus | smad | 0.0057 | 0.0027 | 0.0027 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0023 | 0.0392 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0101 | 0.0058 | 0.2079 |
Schistosoma mansoni | hypothetical protein | 0.016 | 0.0101 | 0.0101 |
Schistosoma mansoni | lipoxygenase | 0.0085 | 0.0047 | 0.0047 |
Onchocerca volvulus | 0.0025 | 0.0003 | 0.0093 | |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0047 | 0.0019 | 0.0565 |
Echinococcus granulosus | cathepsin l1 | 0.0067 | 0.0034 | 0.0034 |
Schistosoma mansoni | hypothetical protein | 0.0346 | 0.0234 | 0.0234 |
Brugia malayi | Cathepsin L-like precursor | 0.0101 | 0.0058 | 0.0977 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0383 | 0.0261 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0144 | 0.0089 | 0.0191 |
Brugia malayi | Bromodomain containing protein | 0.0032 | 0.0008 | 0.0136 |
Loa Loa (eye worm) | glutaminase 2 | 0.033 | 0.0223 | 0.3775 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0285 | 0.0191 | 0.4965 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0101 | 0.0058 | 0.1939 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0053 | 0.0023 | 0.0392 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0025 | 0.0003 | 0.0003 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0012 | 0.0267 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0005 | 0.009 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Echinococcus multilocularis | expressed protein | 0.0034 | 0.001 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0023 | 0.0392 |
Schistosoma mansoni | Smad4 | 0.0026 | 0.0004 | 0.0004 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Entamoeba histolytica | cysteine protease, putative | 0.0052 | 0.0023 | 0.0544 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0144 | 0.0089 | 0.0198 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0007 | 0.0123 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0052 | 0.0023 | 0.058 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0144 | 0.0089 | 0.0089 |
Brugia malayi | Cathepsin L-like precursor | 0.0101 | 0.0058 | 0.0977 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0037 | 0.0012 | 0.0417 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0006 | 0.0107 |
Onchocerca volvulus | 0.0101 | 0.0058 | 0.1683 | |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0084 | 0.1425 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0053 | 0.0023 | 0.0392 |
Loa Loa (eye worm) | beta-lactamase | 0.0144 | 0.0089 | 0.1503 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0005 | 0.0072 |
Schistosoma mansoni | nuclear hormone receptor | 0.0025 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | DR-78 | 0.0025 | 0.0003 | 0.0054 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0058 | 0.0027 | 0.0731 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0112 | 0.0066 | 0.1859 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.003 | 0.0514 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0005 | 0.0072 |
Brugia malayi | conserved hypotetical protein | 0.0025 | 0.0003 | 0.0054 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0338 | 0.0229 | 0.8726 |
Loa Loa (eye worm) | hypothetical protein | 0.0382 | 0.0261 | 0.4409 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0003 | 0.0015 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0047 | 0.0019 | 0.0319 |
Brugia malayi | nuclear receptor NHR-67 | 0.0025 | 0.0003 | 0.0054 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0004 | 0.0122 |
Plasmodium vivax | vivapain-2 | 0.0101 | 0.0058 | 0.1501 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0057 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0009 | 0.0157 |
Onchocerca volvulus | Cathepsin F homolog | 0.0101 | 0.0058 | 0.1683 |
Echinococcus multilocularis | cysteine protease | 0.0101 | 0.0058 | 0.0058 |
Loa Loa (eye worm) | glutaminase | 0.033 | 0.0223 | 0.3775 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0019 | 0.0468 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.001 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 0.0191 | 0.3232 |
Plasmodium vivax | vivapain-2 | 0.0101 | 0.0058 | 0.1501 |
Brugia malayi | hypothetical protein | 0.0332 | 0.0224 | 0.3797 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0112 | 0.0066 | 0.0141 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0066 | 0.0033 | 0.0058 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0112 | 0.0066 | 0.1719 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0053 | 0.0023 | 0.0676 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0025 | 0.0003 | 0.0054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0034 | 0.0908 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0028 | 0.0005 | 0.0005 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0164 | 0.0104 | 0.0236 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0025 | 0.0003 | 0.0003 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0095 | 0.0054 | 0.0054 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0554 | 0.0385 | 0.0385 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0319 | 0.0215 | 0.8216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0015 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0089 | 0.1503 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.004 | 0.0014 | 0.0245 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0052 | 0.0023 | 0.0712 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0072 | 0.0037 | 0.0631 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0053 | 0.0023 | 0.0392 |
Onchocerca volvulus | 0.0297 | 0.0199 | 0.5812 | |
Schistosoma mansoni | cpg binding protein | 0.0057 | 0.0027 | 0.0027 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0044 | 0.0017 | 0.049 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0053 | 0.0023 | 0.0023 |
Toxoplasma gondii | exonuclease III APE | 0.0058 | 0.0027 | 0.0605 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0112 | 0.0066 | 0.0134 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Loa Loa (eye worm) | ctsf protein | 0.0101 | 0.0058 | 0.0977 |
Schistosoma mansoni | nuclear receptor | 0.0025 | 0.0003 | 0.0003 |
Brugia malayi | Cathepsin L-like precursor | 0.0067 | 0.0034 | 0.0572 |
Plasmodium vivax | vivapain-3 | 0.0052 | 0.0023 | 0.0588 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.007 | 0.0035 | 0.06 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.004 | 0.0014 | 0.0014 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0025 | 0.0003 | 0.0003 |
Echinococcus granulosus | intermediate filament protein | 0.0135 | 0.0082 | 0.0082 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.005 | 0.0022 | 0.0366 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0058 | 0.0027 | 0.0463 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0112 | 0.0066 | 0.0134 |
Brugia malayi | jmjC domain containing protein | 0.004 | 0.0014 | 0.0245 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.0013 | 0.0217 |
Schistosoma mansoni | survival motor neuron protein | 0.0097 | 0.0055 | 0.0055 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.0035 | 0.0035 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0053 | 0.0023 | 0.0392 |
Schistosoma mansoni | hypothetical protein | 0.0332 | 0.0224 | 0.0224 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0037 | 0.0012 | 0.0299 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0101 | 0.0058 | 0.1612 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0122 | 0.0073 | 0.0073 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0016 | 0.0372 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0383 | 0.0261 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0382 | 0.0261 | 0.0623 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0072 | 0.0037 | 0.0631 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.035 | 0.0237 | 0.9068 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0101 | 0.0058 | 0.0058 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0003 | 0.0015 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0363 | 0.0247 | 0.0596 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0005 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0382 | 0.0261 | 0.4409 |
Schistosoma mansoni | DNA topoisomerase II | 0.0338 | 0.0229 | 0.0229 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0025 | 0.0003 | 0.0003 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0053 | 0.0023 | 0.0023 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0112 | 0.0066 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0297 | 0.0199 | 0.3374 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0047 | 0.0019 | 0.0565 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.0033 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0097 | 0.0055 | 0.0113 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0112 | 0.0066 | 0.1719 |
Echinococcus multilocularis | lamin dm0 | 0.0135 | 0.0082 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0003 | 0.0054 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0841 | 0.0591 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0285 | 0.0191 | 0.4965 |
Echinococcus granulosus | cathepsin L | 0.0052 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0026 | 0.0004 | 0.0064 |
Onchocerca volvulus | 0.0497 | 0.0343 | 1 | |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0122 | 0.0073 | 0.0073 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0058 | 0.0027 | 0.0718 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0028 | 0.0005 | 0.009 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0037 | 0.0012 | 0.0299 |
Onchocerca volvulus | 0.0075 | 0.0039 | 0.1149 | |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0112 | 0.0066 | 0.1119 |
Schistosoma mansoni | lipoxygenase | 0.0122 | 0.0073 | 0.0073 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0101 | 0.0058 | 0.1501 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0112 | 0.0066 | 0.0141 |
Schistosoma mansoni | zinc finger protein | 0.0023 | 0.0002 | 0.0002 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0012 | 0.0267 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0025 | 0.0003 | 0.0054 |
Onchocerca volvulus | 0.0144 | 0.0089 | 0.2589 | |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0053 | 0.0023 | 0.0392 |
Schistosoma mansoni | bromodomain containing protein | 0.0068 | 0.0034 | 0.0034 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0015 | 0.0015 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0332 | 0.0224 | 0.0224 |
Mycobacterium tuberculosis | Integral membrane indolylacetylinositol arabinosyltransferase EmbA (arabinosylindolylacetylinositol synthase) | 0.5556 | 0.3989 | 1 |
Leishmania major | cathepsin L-like protease | 0.0383 | 0.0261 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0019 | 0.0317 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.0081 | 0.1364 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0148 | 0.0092 | 0.3401 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0001 | 0.0001 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0005 | 0.009 |
Schistosoma mansoni | thyroid hormone receptor | 0.031 | 0.0208 | 0.0208 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0075 | 0.0039 | 0.0039 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0554 | 0.0385 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0081 | 0.0044 | 0.0044 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
26 literature references were collected for this gene.