Detailed information for compound 547955

Basic information

Technical information
  • TDR Targets ID: 547955
  • Name: 2-[(2S,3R,4R,5S,6R)-3-amino-2,5-dihydroxy-6-( phosphonooxymethyl)tetrahydropyran-4-yl]oxypr opanoic acid
  • MW: 331.214 | Formula: C9H18NO10P
  • H donors: 6 H acceptors: 7 LogP: -6.24 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(=O)C(O[C@H]1[C@H](O)[C@@H](COP(=O)(O)O)O[C@@H]([C@@H]1N)O)C
  • InChi: 1S/C9H18NO10P/c1-3(8(12)13)19-7-5(10)9(14)20-4(6(7)11)2-18-21(15,16)17/h3-7,9,11,14H,2,10H2,1H3,(H,12,13)(H2,15,16,17)/t3?,4-,5-,6-,7-,9+/m1/s1
  • InChiKey: FJABMBOKQGQIII-KDBDHQKJSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[[(2S,3R,4R,5S,6R)-3-amino-2,5-dihydroxy-6-(phosphonooxymethyl)-4-tetrahydropyranyl]oxy]propanoic acid
  • 2-[(2S,3R,4R,5S,6R)-3-azanyl-2,5-dihydroxy-6-(phosphonooxymethyl)oxan-4-yl]oxypropanoic acid
  • 2-[(2S,3R,4R,5S,6R)-3-amino-2,5-dihydroxy-6-(phosphonooxymethyl)tetrahydropyran-4-yl]oxypropionic acid
  • 2-[(2S,3R,4R,5S,6R)-3-amino-2,5-dihydroxy-6-(phosphonooxymethyl)oxan-4-yl]oxypropanoic acid
  • muramic acid-6-phosphate
  • 15454-37-2
  • Muramic acid, 6-(dihydrogen phosphate)

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0188 0.0836 0.1162
Entamoeba histolytica hypothetical protein 0.0083 0.0296 0.5
Schistosoma mansoni tar DNA-binding protein 0.0189 0.0845 0.1175
Onchocerca volvulus 0.0083 0.0296 0.0291
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0389 0.1876 0.2618
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0099 0.0379 0.0522
Loa Loa (eye worm) bromodomain containing protein 0.0147 0.0626 0.0713
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0083 0.0296 0.256
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0093 0.0123
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0286 0.1345 0.134
Loa Loa (eye worm) hypothetical protein 0.0306 0.1451 0.1654
Loa Loa (eye worm) PHD-finger family protein 0.0172 0.0753 0.0859
Brugia malayi SET domain containing protein 0.0093 0.0343 0.0391
Brugia malayi PHD-finger family protein 0.0207 0.0938 0.107
Trypanosoma cruzi ISWI complex protein 0.0127 0.0523 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0275 0.5
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0247 0.1141 0.1589
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0389 0.1876 0.2618
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0275 0.5
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0104 0.0404 0.0558
Onchocerca volvulus 0.0083 0.0296 0.0291
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0187 0.3493
Echinococcus multilocularis peregrin 0.0052 0.0131 0.0175
Loa Loa (eye worm) hypothetical protein 0.0083 0.0296 0.0338
Loa Loa (eye worm) MH2 domain-containing protein 0.0254 0.1181 0.1347
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0097 0.0366 0.0504
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0008
Trichomonas vaginalis chromobox protein, putative 0.051 0.2506 0.2277
Plasmodium vivax hypothetical protein, conserved 0.0083 0.0296 0.256
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0187 0.3493
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0029 0.0032
Brugia malayi M-phase phosphoprotein, mpp8 0.0083 0.0296 0.0338
Echinococcus multilocularis tumor protein p63 0.105 0.5301 0.7411
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0275 1
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0187 0.3493
Schistosoma mansoni chromobox protein 0.0083 0.0296 0.0407
Loa Loa (eye worm) RNA binding protein 0.0189 0.0845 0.0963
Brugia malayi RNA recognition motif domain containing protein 0.0189 0.0845 0.0963
Schistosoma mansoni microtubule-associated protein tau 0.1407 0.7151 1
Echinococcus multilocularis Chromobox protein 3 0.0083 0.0296 0.0407
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0497 0.2438 0.3404
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0275 0.5
Onchocerca volvulus 0.033 0.1574 0.1569
Brugia malayi RNA binding protein 0.0189 0.0845 0.0963
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0275 0.5
Schistosoma mansoni tar DNA-binding protein 0.0189 0.0845 0.1175
Trichomonas vaginalis chromobox protein, putative 0.0308 0.1457 0.1197
Schistosoma mansoni bromodomain containing protein 0.0036 0.0048 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0202 0.0912 0.0635
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0238 0.1094 0.1523
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0083 0.0296 0.0338
Brugia malayi Valyl-tRNA synthetase 0.0083 0.0296 0.0338
Schistosoma mansoni bromodomain containing protein 0.0527 0.2593 0.362
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0187 0.3493
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0308 0.1457 0.1453
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0083 0.0296 0.0407
Trypanosoma cruzi ISWI complex protein 0.0127 0.0523 1
Loa Loa (eye worm) hypothetical protein 0.0083 0.0296 0.0338
Plasmodium vivax SET domain containing protein 0.0029 0.0013 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1345 0.1081
Schistosoma mansoni tar DNA-binding protein 0.0189 0.0845 0.1175
Schistosoma mansoni chromobox protein 0.0083 0.0296 0.0407
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0187 0.3493
Brugia malayi MH2 domain containing protein 0.0254 0.1181 0.1347
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0007 0.0011
Echinococcus granulosus fetal alzheimer antigen falz 0.0188 0.0836 0.1162
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0247 0.1141 0.1589
Brugia malayi Probable ClpP-like protease 0.0079 0.0275 0.0314
Loa Loa (eye worm) hypothetical protein 0.0083 0.0296 0.0338
Schistosoma mansoni hypothetical protein 0.0172 0.0753 0.1047
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0275 1
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0029 0.0033
Brugia malayi jmjC domain containing protein 0.0104 0.0404 0.0461
Schistosoma mansoni chromobox protein 0.051 0.2506 0.3499
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0083 0.0296 1
Loa Loa (eye worm) hypothetical protein 0.0319 0.1518 0.1731
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0083 0.0296 0.0407
Schistosoma mansoni hypothetical protein 0.0097 0.0366 0.0504
Trichomonas vaginalis chromobox protein, putative 0.051 0.2506 0.2277
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0187 0.3493
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0029 0.0204
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0083 0.0296 1
Loa Loa (eye worm) hypothetical protein 0.0154 0.0659 0.0752
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0306 0.1451 0.1654
Echinococcus granulosus tumor protein p63 0.105 0.5301 0.7411
Loa Loa (eye worm) transcription factor SMAD2 0.0254 0.1181 0.1347
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0389 0.1876 0.2618
Echinococcus granulosus Chromo domain 0.0083 0.0296 0.0407
Echinococcus granulosus tar DNA binding protein 0.0189 0.0845 0.1175
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0097 0.0366 0.0504
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0133 0.5
Loa Loa (eye worm) hypothetical protein 0.0339 0.162 0.1848
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0099 0.0379 0.0522
Trichomonas vaginalis conserved hypothetical protein 0.0202 0.0912 0.0635
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0389 0.1876 0.214
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0006 0.0006
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0093 0.0123
Schistosoma mansoni jumonji/arid domain-containing protein 0.0054 0.0146 0.0196
Plasmodium falciparum heterochromatin protein 1 0.0083 0.0296 1
Echinococcus multilocularis microtubule associated protein 2 0.1407 0.7151 1
Echinococcus granulosus peregrin 0.0052 0.0131 0.0175
Schistosoma mansoni cellular tumor antigen P53 0.0154 0.0659 0.0915
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0083 0.0296 0.0407
Brugia malayi hypothetical protein 0.0028 0.0007 0.0008
Brugia malayi intermediate filament protein 0.0027 0.0006 0.0006
Echinococcus granulosus GPCR family 2 0.0097 0.0366 0.0504
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0083 0.0296 0.256
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0299 0.1413 0.197
Brugia malayi Latrophilin receptor protein 2 0.0097 0.0366 0.0417
Echinococcus granulosus methyl CpG binding domain protein 2 0.0142 0.0599 0.0831
Brugia malayi Protein cec-1. 0.0083 0.0296 0.0338
Brugia malayi Bromodomain containing protein 0.0052 0.0131 0.0149
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0133 0.4744
Loa Loa (eye worm) hypothetical protein 0.0055 0.0147 0.0167
Schistosoma mansoni methyl-cpg binding protein mbd 0.0142 0.0599 0.0831
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1345 0.1081
Loa Loa (eye worm) hypothetical protein 0.0097 0.0366 0.0417
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0306 0.1451 0.1654
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0007 0.0042
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0083 0.0296 0.5
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0275 0.0377
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0159 0.295
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0029 0.0204
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0275 0.0377
Echinococcus multilocularis GPCR, family 2 0.0097 0.0366 0.0504
Loa Loa (eye worm) hypothetical protein 0.0079 0.0275 0.0314
Echinococcus granulosus microtubule associated protein 2 0.1407 0.7151 1
Schistosoma mansoni hypothetical protein 0.0032 0.0029 0.0032
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0097 0.0366 0.0504
Brugia malayi chromobox protein homolog 3 0.0286 0.1345 0.1534
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0063 0.0081
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0097 0.0366 0.0504
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0029 0.0204
Echinococcus multilocularis zinc finger protein 0.0163 0.0708 0.0983
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0247 0.1141 1
Loa Loa (eye worm) heterochromatin protein 1 0.051 0.2506 0.2858
Giardia lamblia PHD finger protein 15 0.0032 0.0029 0.5
Schistosoma mansoni jumonji domain containing protein 0.0083 0.0293 0.0402
Loa Loa (eye worm) TAR-binding protein 0.0189 0.0845 0.0963
Plasmodium vivax heterochromatin protein 1, putative 0.0083 0.0296 0.256
Schistosoma mansoni hypothetical protein 0.0209 0.0949 0.132
Toxoplasma gondii histone lysine methyltransferase SET1 0.0029 0.0013 0.0064
Trichomonas vaginalis chromobox protein, putative 0.0308 0.1457 0.1197
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0275 0.2376
Entamoeba histolytica hypothetical protein 0.0083 0.0296 0.5
Onchocerca volvulus Alhambra homolog 0.0032 0.0029 0.0023
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0187 0.3493
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0275 0.2376
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.033 0.1574 0.2194
Trypanosoma brucei ISWI complex protein 0.0127 0.0523 1
Echinococcus granulosus Chromobox protein 3 0.0083 0.0296 0.0407
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0187 0.3493
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0033
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0083 0.0296 0.256
Loa Loa (eye worm) hypothetical protein 0.0083 0.0296 0.0338
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0275 0.0377
Echinococcus multilocularis chromobox protein 1 0.051 0.2506 0.3499
Schistosoma mansoni hypothetical protein 0.0083 0.0296 0.0407
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0189 0.0845 0.0963
Onchocerca volvulus 0.0224 0.1025 0.102
Schistosoma mansoni hypothetical protein 0.0097 0.0366 0.0504
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0188 0.0836 0.1162
Schistosoma mansoni hypothetical protein 0.0097 0.0366 0.0504
Brugia malayi TAR-binding protein 0.0189 0.0845 0.0963
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0083 0.0296 0.0407
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0187 0.3493
Loa Loa (eye worm) hypothetical protein 0.0083 0.0296 0.0338
Loa Loa (eye worm) hypothetical protein 0.0286 0.1345 0.1534
Echinococcus multilocularis tar DNA binding protein 0.0189 0.0845 0.1175
Schistosoma mansoni tar DNA-binding protein 0.0189 0.0845 0.1175
Loa Loa (eye worm) latrophilin receptor protein 2 0.0097 0.0366 0.0417
Schistosoma mansoni zinc finger protein 0.0127 0.0523 0.0725
Brugia malayi Bromodomain containing protein 0.0319 0.1515 0.1728
Echinococcus multilocularis chromobox protein 1 0.051 0.2506 0.3499
Schistosoma mansoni tar DNA-binding protein 0.0189 0.0845 0.1175
Schistosoma mansoni jumonji/arid domain-containing protein 0.0054 0.0146 0.0196
Leishmania major cathepsin L-like protease 0.0062 0.0187 0.3493
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0118 0.2153
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0003
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0133 0.0179
Loa Loa (eye worm) hypothetical protein 0.0589 0.2913 0.3322
Leishmania major cathepsin L-like protease 0.0062 0.0187 0.3493
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0133 0.5
Echinococcus granulosus lysine specific demethylase 5A 0.0054 0.0146 0.0196
Loa Loa (eye worm) hypothetical protein 0.0083 0.0296 0.0338
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0029 0.0032
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0133 0.0179
Plasmodium vivax SET domain protein, putative 0.0247 0.1141 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0083 0.0296 0.5
Echinococcus granulosus histone lysine methyltransferase setb 0.0389 0.1876 0.2618
Loa Loa (eye worm) hypothetical protein 0.0355 0.1703 0.1942
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0204 0.0233
Brugia malayi hypothetical protein 0.0083 0.0296 0.0338
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0299 0.1413 0.197
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0099 0.0379 0.0522
Schistosoma mansoni chromobox protein 0.051 0.2506 0.3499
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0187 0.3493
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0187 0.3493
Echinococcus granulosus zinc finger protein 0.0163 0.0708 0.0983
Echinococcus multilocularis Chromo domain 0.0083 0.0296 0.0407
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0275 0.9281
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0497 0.2438 0.3404
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0187 0.3493
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0142 0.0599 0.0831
Brugia malayi CHD4 protein 0.0099 0.0379 0.0432
Brugia malayi Pre-SET motif family protein 0.1719 0.877 1
Loa Loa (eye worm) hypothetical protein 0.0209 0.0949 0.1082
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0007 0.0011
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0275 0.5
Schistosoma mansoni hypothetical protein 0.0127 0.0523 0.0725
Brugia malayi PHD-finger family protein 0.0032 0.0029 0.0033
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0083 0.0296 0.5
Brugia malayi Heterochromatin protein 1 0.051 0.2506 0.2858
Loa Loa (eye worm) jmjC domain-containing protein 0.0054 0.0146 0.0166
Plasmodium vivax hypothetical protein, conserved 0.0083 0.0296 0.256
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0104 0.0404 0.0558
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0083 0.0296 0.0407
Loa Loa (eye worm) hypothetical protein 0.0036 0.0048 0.0055
Brugia malayi jmjC domain containing protein 0.0054 0.0146 0.0166
Trichomonas vaginalis set domain proteins, putative 0.1957 1 1
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0275 0.2376
Leishmania major hypothetical protein, conserved 0.0127 0.0523 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0029 0.0032
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0097 0.0366 0.0417
Brugia malayi Pre-SET motif family protein 0.0247 0.1141 0.1301
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1719 0.877 1
Schistosoma mansoni hypothetical protein 0.0097 0.0366 0.0504
Schistosoma mansoni methyl-cpg binding protein mbd 0.0142 0.0599 0.0831
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0187 0.3493
Plasmodium falciparum phd finger protein, putative 0.0032 0.0029 0.0799
Brugia malayi Associated with TFs and helicases family protein 0.0083 0.0296 0.0338
Entamoeba histolytica hypothetical protein 0.0083 0.0296 0.5
Loa Loa (eye worm) helicase 0.0083 0.0296 0.0338
Brugia malayi F/Y-rich N-terminus family protein 0.0035 0.0047 0.0054
Leishmania major cathepsin L-like protease 0.0062 0.0187 0.3493
Schistosoma mansoni zinc finger protein 0.0163 0.0708 0.0983
Echinococcus granulosus chromobox protein 2 0.0083 0.0296 0.0407
Brugia malayi latrophilin 2 splice variant baaae 0.0209 0.0949 0.1082
Brugia malayi Calcitonin receptor-like protein seb-1 0.0306 0.1451 0.1654
Onchocerca volvulus 0.0154 0.0659 0.0654
Brugia malayi Bromodomain containing protein 0.0624 0.3098 0.3533
Echinococcus granulosus chromobox protein 1 0.051 0.2506 0.3499
Loa Loa (eye worm) CHromoDomain protein family member 0.0099 0.0379 0.0432
Echinococcus granulosus chromobox protein 1 0.051 0.2506 0.3499
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0187 0.3493
Loa Loa (eye worm) hypothetical protein 0.0083 0.0296 0.0338
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0187 0.3493
Echinococcus multilocularis chromobox protein 2 0.0083 0.0296 0.0407
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0007 0.0042
Loa Loa (eye worm) hypothetical protein 0.0224 0.1025 0.1169

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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