Detailed information for compound 548190

Basic information

Technical information
  • TDR Targets ID: 548190
  • Name: tetrapotassium [oxido(oxidooxy)phosphoryl] ph osphate
  • MW: 350.368 | Formula: H4K4O8P2
  • H donors: 0 H acceptors: 6 LogP: -3.46 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]OP(=O)(OP(=O)([O-])[O-])[O-].[KH+].[KH+].[KH+].[KH+]
  • InChi: 1S/4K.H4O8P2/c;;;;1-7-10(5,6)8-9(2,3)4/h;;;;1H,(H,5,6)(H2,2,3,4)/q4*+1;/p-4
  • InChiKey: PEKPGBKEIWFPAS-UHFFFAOYSA-J  


Substructure search Similarity search

Network

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Synonyms

  • tetrapotassium [oxidanidyl(oxidanidyloxy)phosphoryl] phosphate
  • tetrapotassium peroxydiphosphate
  • tetrapotassium (oxido-oxidooxyphosphoryl) phosphate
  • tetrapotassium (oxido-oxidooxy-phosphoryl) phosphate
  • 15593-49-4
  • EINECS 239-665-9
  • Tetrapotassium peroxydiphosphorate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi nuclear hormone receptor 0.002 0.006 0.0187
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.006 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.006 0.0187
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0177 0.0426
Loa Loa (eye worm) hypothetical protein 0.011 0.1368 0.3294
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.006 0.0187
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.279 0.6719
Mycobacterium tuberculosis Probable lipase LipD 0.011 0.1368 0.1329
Schistosoma mansoni ran 0.0021 0.0069 0.0165
Schistosoma mansoni hypothetical protein 0.0301 0.4153 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0453 0.109
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0511 0.123
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0467 0.1458
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.02 0.0481
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.006 0.0187
Schistosoma mansoni thyroid hormone receptor 0.002 0.006 0.0145
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0271 0.0847
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.006 0.0145
Schistosoma mansoni hypothetical protein 0.0021 0.0072 0.0173
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0471 0.1134
Schistosoma mansoni survival motor neuron protein 0.0048 0.0467 0.1124
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.006 0.0187
Echinococcus multilocularis snurportin 1 0.0301 0.4153 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0303 0.1949
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0303 0.1949
Brugia malayi RNA, U transporter 1 0.008 0.0935 0.2919
Schistosoma mansoni inositol monophosphatase 0.0037 0.0303 0.0729
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.3202 0.5779
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.011 0.1368 0.3294
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0045 0.0081
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0511 0.0922
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0453 0.109
Echinococcus granulosus beta LACTamase domain containing family member 0.011 0.1368 0.2469
Brugia malayi Bromodomain containing protein 0.0039 0.0334 0.1043
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.01 0.0242
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.006 0.0145
Echinococcus granulosus snurportin 1 0.0301 0.4153 0.7495
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0069 0.0179
Leishmania major hypothetical protein, conserved 0.011 0.1368 1
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0145
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.006 0.0108
Loa Loa (eye worm) hypothetical protein 0.0051 0.0505 0.1216
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.006 0.0145
Brugia malayi Importin beta-1 subunit 0.0028 0.0177 0.0553
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0028 0.0068
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0069 0.0179
Brugia malayi ecdysteroid receptor 0.002 0.006 0.0187
Schistosoma mansoni nuclear hormone receptor 0.002 0.006 0.0145
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0471 0.085
Mycobacterium leprae Probable lipase LipE 0.011 0.1368 1
Plasmodium vivax importin-beta 2, putative 0.0028 0.0177 0.0999
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.006 0.0108
Mycobacterium tuberculosis Probable hydrolase 0.011 0.1368 0.1329
Toxoplasma gondii hypothetical protein 0.0027 0.0158 0.0852
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0177 0.0999
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0303 0.0547
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0453 0.109
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.006 0.0187
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0303 0.0729
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0158 0.1314
Loa Loa (eye worm) hypothetical protein 0.0041 0.037 0.0891
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0078 0.0903 0.6482
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0069 0.0214
Echinococcus multilocularis FTZ F1 alpha 0.002 0.006 0.0145
Loa Loa (eye worm) beta-lactamase 0.011 0.1368 0.3294
Loa Loa (eye worm) hypothetical protein 0.0236 0.3202 0.771
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.006 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.006 0.0187
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.006 0.0145
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0247 0.0735
Brugia malayi Bromodomain containing protein 0.0076 0.0878 0.2742
Loa Loa (eye worm) hypothetical protein 0.011 0.1368 0.3294
Onchocerca volvulus 0.0048 0.0467 0.1293
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0303 0.1949
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0099 0.0172
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.02 0.0481
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.006 0.0187
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.011 0.1368 0.1329
Schistosoma mansoni inositol monophosphatase 0.0037 0.0303 0.0729
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.1368 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0078 0.0903 0.6154
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0303 0.0815
Entamoeba histolytica hypothetical protein 0.0023 0.0099 0.211
Mycobacterium ulcerans esterase/lipase LipP 0.011 0.1368 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.006 0.0145
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.011 0.1368 0.3294
Schistosoma mansoni thyroid hormone receptor 0.002 0.006 0.0145
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0145
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.006 0.0108
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0505 0.1578
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0303 0.0815
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0453 0.109
Loa Loa (eye worm) hypothetical protein 0.0043 0.0398 0.0959
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0471 0.1134
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.006 0.0187
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.006 0.0145
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0069 0.0124
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.01 0.0181
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.006 0.0145
Mycobacterium tuberculosis Probable esterase LipL 0.011 0.1368 0.1329
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0471 0.1471
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0303 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0651 0.1568
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.1368 0.4182
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0303 0.1949
Mycobacterium tuberculosis Conserved protein 0.011 0.1368 0.1329
Onchocerca volvulus 0.011 0.1368 0.4154
Plasmodium vivax hypothetical protein, conserved 0.011 0.1368 1
Brugia malayi Steroid receptor seven-up type 2 0.002 0.006 0.0187
Onchocerca volvulus 0.003 0.02 0.0444
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.006 0.0145
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0045 0.0108
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0069 0.0179
Echinococcus granulosus importin subunit beta 1 0.0028 0.0177 0.032
Schistosoma mansoni coup transcription factor 0.002 0.006 0.0145
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.006 0.0145
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0301 0.4153 1
Brugia malayi Probable ClpP-like protease 0.0078 0.0903 0.2818
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0158 0.1314
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0303 0.1949
Echinococcus multilocularis beta LACTamase domain containing family member 0.011 0.1368 0.3294
Plasmodium falciparum importin beta, putative 0.0028 0.0177 0.1541
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0903 0.5
Brugia malayi Inositol-1 0.0037 0.0303 0.0946
Mycobacterium ulcerans beta-lactamase 0.011 0.1368 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0177 0.0999
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.006 0.0145
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.3202 0.771
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.006 0.0187
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.01 0.0242
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0903 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.011 0.1368 0.1329
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.1368 0.4182
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0099 0.0172
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.006 0.0145
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.006 0.0145
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.011 0.1368 0.4272
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.006 0.0187
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0453 0.0817
Loa Loa (eye worm) hypothetical protein 0.0028 0.0177 0.0426
Mycobacterium tuberculosis Conserved protein 0.011 0.1368 0.1329
Entamoeba histolytica Ran family GTPase 0.0021 0.0069 0.0917
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0505 0.1216
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.02 0.0481
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.006 0.0145
Trichomonas vaginalis esterase, putative 0.011 0.1368 0.4182
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.006 0.0187
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.006 0.0108
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0099 0.0411
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0069 0.0165
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0471 0.1134
Loa Loa (eye worm) hypothetical protein 0.011 0.1368 0.3294
Echinococcus granulosus FTZ F1 alpha 0.0396 0.5541 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0303 0.0815
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.006 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.006 0.0145
Onchocerca volvulus 0.011 0.1368 0.4154
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0247 0.0203
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.006 0.0145
Brugia malayi PHD-finger family protein 0.0025 0.0135 0.0423
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0511 0.292
Brugia malayi steroid hormone receptor 0.002 0.006 0.0187
Loa Loa (eye worm) steroid hormone receptor 0.002 0.006 0.0145
Brugia malayi beta-lactamase family protein 0.011 0.1368 0.4272
Loa Loa (eye worm) hypothetical protein 0.011 0.1368 0.3294
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.006 0.0145
Brugia malayi Pre-SET motif family protein 0.003 0.02 0.0624
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.006 0.0187
Loa Loa (eye worm) inositol-1 0.0037 0.0303 0.0729
Echinococcus multilocularis zinc finger protein 0.002 0.0056 0.0136
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.006 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.006 0.0187
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.006 0.0145
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0145
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0303 0.3007
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0303 0.1949
Brugia malayi Pre-SET motif family protein 0.0207 0.279 0.8714
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.011 0.1368 0.1329
Loa Loa (eye worm) hypothetical protein 0.011 0.1368 0.3294
Trichomonas vaginalis penicillin-binding protein, putative 0.011 0.1368 0.4182
Schistosoma mansoni hypothetical protein 0.0035 0.0271 0.0653
Leishmania major importin beta-1 subunit, putative 0.0023 0.0099 0.0411
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0078 0.0903 0.2173
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.006 0.0108
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0069 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.006 0.0187
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0078 0.0903 0.1629
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0069 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.011 0.1368 0.3294
Loa Loa (eye worm) hypothetical protein 0.0035 0.0271 0.0653
Loa Loa (eye worm) hypothetical protein 0.0072 0.0815 0.1961
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0903 0.6482
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0019 0.0046
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0903 0.6482
Onchocerca volvulus 0.011 0.1368 0.4154
Brugia malayi beta-lactamase family protein 0.011 0.1368 0.4272
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0471 0.1134
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0903 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0019 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.006 0.0145
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0072 0.0173
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0651 0.1175
Schistosoma mansoni ran 0.0021 0.0069 0.0165
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.1368 0.4182
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0145
Echinococcus granulosus zinc finger protein 0.002 0.0056 0.0102
Loa Loa (eye worm) hypothetical protein 0.011 0.1368 0.3294
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.011 0.1368 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0505 0.1578
Brugia malayi hypothetical protein 0.0236 0.3202 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.006 0.0108
Mycobacterium ulcerans lipase LipD 0.011 0.1368 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.006 0.0145
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0903 0.6482
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0471 0.1134
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.02 0.1171
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0145
Brugia malayi nuclear receptor NHR-88 0.002 0.006 0.0187
Schistosoma mansoni ap endonuclease 0.0019 0.0045 0.0108
Trichomonas vaginalis set domain proteins, putative 0.0236 0.3208 1
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0158 0.0852
Schistosoma mansoni zinc finger protein 0.002 0.0056 0.0136
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0019 0.0046
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.006 0.0145
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0511 0.0468
Plasmodium vivax SET domain protein, putative 0.003 0.02 0.1171
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.1368 1
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.006 0.0187
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0299 0.0539
Brugia malayi beta-lactamase 0.011 0.1368 0.4272
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0511 0.0468
Toxoplasma gondii ABC1 family protein 0.011 0.1368 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0177 0.0999
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0903 0.5
Schistosoma mansoni ap endonuclease 0.0019 0.0045 0.0108
Schistosoma mansoni bromodomain containing protein 0.0064 0.0704 0.1696
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0145
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0299 0.072
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0069 0.0165
Schistosoma mansoni hypothetical protein 0.0048 0.0467 0.1124
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0903 0.6482
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0045 0.014
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0471 0.1134
Leishmania major GTP-binding protein, putative 0.0021 0.0069 0.0179
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0019 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0145
Loa Loa (eye worm) hypothetical protein 0.0039 0.0335 0.0807
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0045 0.0108
Mycobacterium tuberculosis Conserved protein 0.011 0.1368 0.1329
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0184 0.0332
Trypanosoma brucei hypothetical protein, conserved 0.011 0.1368 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0069 0.0179
Onchocerca volvulus 0.0236 0.3208 1
Schistosoma mansoni importin beta-1 0.0028 0.0177 0.0426
Schistosoma mansoni peptidase Clp (S14 family) 0.0078 0.0903 0.2173
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0078 0.0903 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0069 0.0179
Mycobacterium leprae conserved hypothetical protein 0.011 0.1368 1
Mycobacterium ulcerans hypothetical protein 0.011 0.1368 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0903 0.2173
Trichomonas vaginalis ran, putative 0.0021 0.0069 0.0075
Mycobacterium tuberculosis Probable lipase LipE 0.011 0.1368 0.1329
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.006 0.0145
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0471 0.085
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0099 0.0172
Trichomonas vaginalis penicillin-binding protein, putative 0.011 0.1368 0.4182
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.006 0.0145

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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