Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0009 | 0.0146 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2603 | 0.2603 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0146 | 0.0146 |
Schistosoma mansoni | thyroid hormone receptor | 0.0012 | 0.0296 | 0.0328 |
Brugia malayi | DIX domain containing protein | 0.0009 | 0.0146 | 0.0146 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.0296 | 0.0296 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.0296 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.4205 | 0.4205 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0012 | 0.0296 | 0.0328 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0012 | 0.0296 | 0.0296 |
Schistosoma mansoni | coup transcription factor | 0.0012 | 0.0296 | 0.0328 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0647 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0012 | 0.0296 | 0.0328 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0012 | 0.0296 | 0.0296 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0012 | 0.0296 | 0.0296 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0575 | 0.0637 |
Onchocerca volvulus | 0.0012 | 0.0296 | 0.0296 | |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0296 | 0.0296 |
Echinococcus granulosus | tar DNA binding protein | 0.0067 | 0.3273 | 0.3626 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0146 | 0.0146 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0575 | 0.0575 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.1664 | 0.1844 |
Schistosoma mansoni | nuclear hormone receptor | 0.0012 | 0.0296 | 0.0328 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0647 | 1 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0647 | 1 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0085 | 0.4205 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0647 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0012 | 0.0296 | 0.0296 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0085 | 0.4205 | 1 |
Onchocerca volvulus | 0.0009 | 0.0146 | 0.0146 | |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0012 | 0.0296 | 0.0328 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0647 | 0.5 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0146 | 0.0162 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0192 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1664 | 0.1664 |
Schistosoma mansoni | thyroid hormone receptor | 0.0012 | 0.0296 | 0.0328 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.0296 | 0.0328 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.2603 | 0.2603 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0012 | 0.0296 | 0.0328 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0012 | 0.0296 | 0.0296 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0012 | 0.0296 | 0.0296 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0146 | 0.0162 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0575 | 0.0637 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0012 | 0.0296 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0296 | 0.0296 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0575 | 0.0637 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.0296 | 0.0296 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0575 | 0.0637 |
Schistosoma mansoni | dep domain containing protein | 0.0009 | 0.0146 | 0.0162 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0647 | 0.0717 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.0296 | 0.0328 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.0296 | 0.0328 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0146 | 0.0162 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0009 | 0.0146 | 0.0162 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 1 | 1 |
Schistosoma mansoni | regulator of G protein signaling | 0.0009 | 0.0146 | 0.0162 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0575 | 0.0637 |
Brugia malayi | ecdysteroid receptor | 0.0012 | 0.0296 | 0.0296 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0012 | 0.0296 | 0.0296 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0647 | 0.0647 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.1664 | 0.1664 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0009 | 0.0146 | 0.0146 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Brugia malayi | steroid hormone receptor | 0.0012 | 0.0296 | 0.0296 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3273 | 0.3626 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0575 | 0.0637 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.2603 | 0.2603 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0055 | 0.2631 | 0.2915 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0575 | 0.0575 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0647 | 0.0647 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0647 | 0.0717 |
Loa Loa (eye worm) | RNA binding protein | 0.0067 | 0.3273 | 0.3273 |
Brugia malayi | TAR-binding protein | 0.0067 | 0.3273 | 0.3273 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0575 | 0.0637 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0296 | 0.0296 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0009 | 0.0146 | 0.0146 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.4205 | 1 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0146 | 0.0162 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0009 | 0.0146 | 0.0146 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0575 | 0.0575 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0012 | 0.0296 | 0.0328 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0012 | 0.0296 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0296 | 0.0296 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0012 | 0.0296 | 0.0328 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0647 | 0.0717 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0012 | 0.0296 | 0.0296 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0012 | 0.0296 | 0.0328 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0647 | 0.0717 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0012 | 0.0296 | 0.0296 |
Loa Loa (eye worm) | TAR-binding protein | 0.0067 | 0.3273 | 0.3273 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0012 | 0.0296 | 0.0296 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0146 | 0.0162 |
Echinococcus multilocularis | tar DNA binding protein | 0.0067 | 0.3273 | 0.3626 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0012 | 0.0296 | 0.0296 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0012 | 0.0296 | 0.0296 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0012 | 0.0296 | 0.0296 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3273 | 0.3626 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0575 | 0.0637 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0647 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.0296 | 0.0296 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0012 | 0.0296 | 0.0296 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0085 | 0.4205 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0012 | 0.0296 | 0.0328 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0012 | 0.0296 | 0.0296 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0146 | 0.0162 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0146 | 0.0146 |
Brugia malayi | Probable ClpP-like protease | 0.0085 | 0.4205 | 0.4205 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.9026 | 1 |
Echinococcus granulosus | geminin | 0.0174 | 0.9026 | 1 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.4205 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0146 | 0.0146 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0009 | 0.0146 | 0.0146 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0575 | 0.0575 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0647 | 0.5 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0146 | 0.0162 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.0296 | 0.0328 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0575 | 0.0637 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0647 | 0.0647 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.4205 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.0296 | 0.0296 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0009 | 0.0146 | 0.0162 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0647 | 0.0717 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0085 | 0.4205 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0012 | 0.0296 | 0.0328 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0012 | 0.0296 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0296 | 0.0296 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.4205 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0055 | 0.2631 | 0.4744 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.0296 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0296 | 0.0296 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0009 | 0.0146 | 0.0162 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0012 | 0.0296 | 0.0296 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0146 | 0.0162 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0647 | 1 |
Brugia malayi | RNA binding protein | 0.0067 | 0.3273 | 0.3273 |
Brugia malayi | nuclear receptor NHR-88 | 0.0012 | 0.0296 | 0.0296 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0067 | 0.3273 | 0.3273 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0012 | 0.0296 | 0.0328 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0009 | 0.0146 | 0.0162 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0296 | 0.0296 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0012 | 0.0296 | 0.0328 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.9026 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0647 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0012 | 0.0296 | 0.0296 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0055 | 0.2631 | 1 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0055 | 0.2631 | 0.2915 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.0647 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.0296 | 0.0296 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0647 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0012 | 0.0296 | 0.0296 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0085 | 0.4205 | 0.4659 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0012 | 0.0296 | 0.0328 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.4205 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.0296 | 0.0328 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.0296 | 0.0328 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.4205 | 1 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.4205 | 0.4659 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3273 | 0.3626 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Echinococcus multilocularis | geminin | 0.0174 | 0.9026 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0296 | 0.0296 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0647 | 0.0717 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0067 | 0.3273 | 0.3273 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3273 | 0.3626 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0296 | 0.0296 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.4205 | 0.4659 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0146 | 0.0162 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0647 | 0.0717 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0029 | 0.1211 | 0.2622 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0647 | 0.0647 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0647 | 1 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0146 | 0.0146 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0012 | 0.0296 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0146 | 0.0146 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0647 | 0.0717 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.0296 | 0.0328 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0055 | 0.2631 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3273 | 0.3626 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.0296 | 0.0328 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0647 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0575 | 0.0637 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.0296 | 0.0328 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0012 | 0.0296 | 0.0296 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.0296 | 0.0296 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.2603 | 0.2603 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0012 | 0.0296 | 0.0328 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.4205 | 0.5 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0146 | 0.0162 |
Echinococcus granulosus | FTZ F1 alpha | 0.0012 | 0.0296 | 0.0328 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0647 | 0.0717 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.