Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0322 | 0.0395 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0653 | 1 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0057 | 0.0703 | 0.0703 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0331 | 0.4983 | 1 |
Brugia malayi | GTP-binding regulatory protein alpha chain - starfish, putative | 0.0023 | 0.0174 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Brugia malayi | glutathione reductase | 0.0037 | 0.04 | 0.05 |
Plasmodium falciparum | phd finger protein, putative | 0.0032 | 0.0321 | 0.4567 |
Treponema pallidum | NADH oxidase | 0.0013 | 0.0023 | 0.0321 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0013 | 0.0023 | 0.0023 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0067 | 0.0862 | 0.1055 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0094 | 0.1288 | 0.2485 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0138 | 0.1966 | 0.2454 |
Onchocerca volvulus | 0.002 | 0.0129 | 0.0258 | |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0023 | 0.0023 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.4983 | 0.6482 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0862 | 0.1055 |
Plasmodium falciparum | conserved Plasmodium membrane protein, unknown function | 0.0012 | 0.0014 | 0.02 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0128 | 0.1823 | 0.2232 |
Echinococcus granulosus | low density lipoprotein receptor ldl | 0.002 | 0.0129 | 0.0158 |
Brugia malayi | Thioredoxin reductase | 0.0037 | 0.04 | 0.05 |
Echinococcus granulosus | basement membrane specific heparan sulfate | 0.002 | 0.0129 | 0.0158 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0105 | 0.1456 | 0.1783 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0023 | 0.0023 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0041 | 0.0466 | 0.0689 |
Leishmania major | hypothetical protein, conserved | 0.0051 | 0.0618 | 0.0618 |
Echinococcus granulosus | low density lipoprotein receptor ldl | 0.002 | 0.0129 | 0.0158 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0179 | 0.022 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0013 | 0.0023 | 0.0023 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0057 | 0.0703 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0013 | 0.0023 | 0.0023 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.002 | 0.0129 | 0.0158 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0106 | 0.013 |
Schistosoma mansoni | hypothetical protein | 0.0433 | 0.656 | 0.8033 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0018 | 0.0106 | 0.0581 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0057 | 0.0703 | 0.1318 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.004 | 0.0453 | 0.0555 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0051 | 0.0618 | 0.8797 |
Loa Loa (eye worm) | low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0129 | 0.0161 |
Entamoeba histolytica | hypothetical protein | 0.0445 | 0.6759 | 1 |
Echinococcus granulosus | low density lipoprotein receptor protein | 0.002 | 0.0129 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0321 | 0.0401 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0129 | 0.0161 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0037 | 0.04 | 0.5696 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0153 | 0.221 | 0.2706 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0526 | 0.8012 | 0.9812 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0057 | 0.0703 | 0.1356 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0349 | 0.5261 | 0.6843 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.002 | 0.013 | 0.0162 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0321 | 0.0393 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0045 | 0.0524 | 0.0682 |
Brugia malayi | Guanine nucleotide-binding protein alpha-12 subunit, putative | 0.0023 | 0.0174 | 0.0217 |
Onchocerca volvulus | 0.002 | 0.0129 | 0.0258 | |
Echinococcus multilocularis | low density lipoprotein receptor (ldl) | 0.002 | 0.0129 | 0.0158 |
Brugia malayi | guanine nucleotide-binding protein alpha-7 subunit, putative | 0.0023 | 0.0174 | 0.0217 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.4983 | 0.6482 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.002 | 0.0129 | 0.0158 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.0618 | 0.0618 |
Schistosoma mansoni | GTP-binding protein alpha subunit | 0.0023 | 0.0174 | 0.0213 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0092 | 0.1253 | 0.1253 |
Schistosoma mansoni | GTP-binding protein (I) alpha-1subunit gnai1 | 0.0023 | 0.0174 | 0.0213 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0018 | 0.0106 | 0.0581 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0067 | 0.0862 | 0.1055 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0037 | 0.04 | 0.04 |
Echinococcus multilocularis | low density lipoprotein receptor protein | 0.002 | 0.0129 | 0.0158 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0051 | 0.0618 | 0.0618 |
Loa Loa (eye worm) | CCR4-NOT transcription complex subunit 6 family protein | 0.0012 | 0.0008 | 0.001 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0106 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0618 | 0.0772 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0023 | 0.0023 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0094 | 0.1288 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0038 | 0.0408 | 0.05 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0505 | 0.7687 | 1 |
Echinococcus multilocularis | gtp binding protein (I) alpha 1subunit | 0.0023 | 0.0174 | 0.0213 |
Onchocerca volvulus | Arrow homolog | 0.002 | 0.0129 | 0.0258 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0505 | 0.7687 | 1 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0018 | 0.0106 | 0.0204 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0085 | 0.1141 | 0.2201 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0066 | 0.0852 | 0.1064 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0092 | 0.1253 | 0.1253 |
Echinococcus multilocularis | Low density lipoprotein receptor, class A, cysteine rich | 0.002 | 0.0129 | 0.0158 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0067 | 0.0862 | 0.1055 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0129 | 0.0161 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0013 | 0.0023 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0862 | 0.1075 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0041 | 0.0466 | 0.6627 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0106 | 0.0106 |
Trichomonas vaginalis | GTP-binding protein alpha subunit, gna, putative | 0.0023 | 0.0174 | 0.0226 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0018 | 0.0106 | 0.013 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0211 | 0.3107 | 0.3878 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0057 | 0.0703 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.4983 | 0.6482 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0013 | 0.0023 | 0.0023 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0018 | 0.0106 | 0.0106 |
Schistosoma mansoni | hypothetical protein | 0.0536 | 0.8166 | 1 |
Schistosoma mansoni | GTP-binding protein alpha subunit | 0.0023 | 0.0174 | 0.0213 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0094 | 0.1288 | 0.2485 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0526 | 0.8012 | 0.9812 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0092 | 0.1253 | 0.1253 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0445 | 0.6759 | 0.8277 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0653 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0526 | 0.8012 | 1 |
Brugia malayi | PHD-finger family protein | 0.0012 | 0.0012 | 0.0015 |
Onchocerca volvulus | 0.002 | 0.0129 | 0.0258 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0526 | 0.8012 | 0.9812 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0128 | 0.1823 | 0.3517 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0057 | 0.0703 | 0.0703 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0526 | 0.8012 | 0.9812 |
Echinococcus multilocularis | guanine nucleotide binding protein (G protein) | 0.0023 | 0.0174 | 0.0213 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Mycobacterium ulcerans | hypothetical protein | 0.0344 | 0.5183 | 1 |
Brugia malayi | basement membrane proteoglycan precursor | 0.002 | 0.0129 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Brugia malayi | MH2 domain containing protein | 0.0138 | 0.1966 | 0.2454 |
Brugia malayi | PHD-finger family protein | 0.0032 | 0.0321 | 0.0401 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0129 | 0.0161 |
Echinococcus granulosus | guanine nucleotide binding protein subunit | 0.0023 | 0.0174 | 0.0213 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.4983 | 0.6482 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0128 | 0.1823 | 0.2232 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0094 | 0.1288 | 0.2485 |
Entamoeba histolytica | hypothetical protein | 0.0445 | 0.6759 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0057 | 0.0703 | 0.0861 |
Echinococcus granulosus | 5'partial|Low density lipoprotein receptor class A cysteine rich | 0.002 | 0.0129 | 0.0158 |
Loa Loa (eye worm) | low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0129 | 0.0161 |
Entamoeba histolytica | G protein alpha subunit, putative | 0.0023 | 0.0174 | 0.0257 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0013 | 0.0023 | 0.0321 |
Echinococcus granulosus | Low density lipoprotein receptor class A cysteine rich | 0.002 | 0.0129 | 0.0158 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0018 | 0.0106 | 0.0106 |
Trichomonas vaginalis | GTP-binding protein (q) alpha-11 subunit, gna11, putative | 0.0023 | 0.0174 | 0.0226 |
Brugia malayi | guanine nucleotide-binding protein G-o protein alpha subunit | 0.0023 | 0.0174 | 0.0217 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0179 | 0.022 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0526 | 0.8012 | 0.9812 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0128 | 0.1823 | 0.2232 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0038 | 0.0408 | 0.05 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.004 | 0.0453 | 0.0555 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.4983 | 0.6482 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0032 | 0.0321 | 0.0393 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0032 | 0.0321 | 0.0401 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0106 | 0.013 |
Echinococcus multilocularis | geminin | 0.0536 | 0.8166 | 1 |
Echinococcus multilocularis | expressed protein | 0.0023 | 0.0174 | 0.0213 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0018 | 0.0106 | 0.1506 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0526 | 0.8012 | 0.9812 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0505 | 0.7687 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0018 | 0.0103 | 0.0126 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0057 | 0.0703 | 0.104 |
Echinococcus granulosus | peregrin | 0.0036 | 0.038 | 0.0465 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0128 | 0.1823 | 0.2232 |
Brugia malayi | guanine nucleotide-binding protein alpha-3 subunit, putative | 0.0023 | 0.0174 | 0.0217 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0862 | 0.1055 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0526 | 0.8012 | 1 |
Brugia malayi | enteropeptidase precursor | 0.002 | 0.0129 | 0.0161 |
Brugia malayi | Guanine nucleotide-binding protein alpha-3 subunit, putative | 0.0023 | 0.0174 | 0.0217 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0045 | 0.0524 | 0.0642 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0032 | 0.0321 | 0.0393 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0067 | 0.0862 | 0.1075 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0012 | 0.001 | 0.0012 |
Schistosoma mansoni | GTP-binding protein alpha subunit gna | 0.0023 | 0.0174 | 0.0213 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0112 | 0.1566 | 0.1566 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0013 | 0.0023 | 0.0321 |
Plasmodium falciparum | glutathione reductase | 0.0013 | 0.0023 | 0.0321 |
Brugia malayi | jmjC domain containing protein | 0.0105 | 0.1456 | 0.1817 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0085 | 0.1141 | 0.2201 |
Echinococcus multilocularis | guanine nucleotide binding protein subunit | 0.0023 | 0.0174 | 0.0213 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0344 | 0.5183 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0505 | 0.7687 | 1 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.002 | 0.0129 | 0.0158 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0013 | 0.0023 | 0.0023 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0129 | 0.0158 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0106 | 0.0106 |
Schistosoma mansoni | GTP-binding protein (I) alpha subunit gnai | 0.0023 | 0.0174 | 0.0213 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0023 | 0.0023 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0179 | 0.022 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0013 | 0.0023 | 0.0124 |
Echinococcus granulosus | gtp binding protein I alpha 1subunit | 0.0023 | 0.0174 | 0.0213 |
Echinococcus multilocularis | GPCR, family 2 | 0.0067 | 0.0862 | 0.1055 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0045 | 0.0524 | 0.7459 |
Echinococcus granulosus | guanine nucleotide binding protein G protein | 0.0023 | 0.0174 | 0.0213 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0105 | 0.1456 | 0.1783 |
Plasmodium vivax | hypothetical protein, conserved | 0.0012 | 0.0014 | 0.02 |
Entamoeba histolytica | hypothetical protein | 0.0445 | 0.6759 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0505 | 0.7687 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0039 | 0.0426 | 0.0522 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.0618 | 0.8797 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0174 | 0.0217 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0128 | 0.1823 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0067 | 0.0862 | 0.1055 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0012 | 0.0015 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0067 | 0.0862 | 0.1075 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.2068 | 0.2581 |
Brugia malayi | Bromodomain containing protein | 0.0036 | 0.038 | 0.0474 |
Brugia malayi | guanine nucleotide-binding protein G(o), alpha subunit, putative | 0.0023 | 0.0174 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Trichomonas vaginalis | GTP-binding protein alpha subunit, gna, putative | 0.0023 | 0.0174 | 0.0226 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0322 | 0.0395 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0013 | 0.0023 | 0.0321 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0018 | 0.0106 | 0.013 |
Loa Loa (eye worm) | calcium binding EGF domain-containing protein | 0.002 | 0.0129 | 0.0161 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0129 | 0.0161 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.4983 | 0.6482 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0067 | 0.0862 | 0.1075 |
Onchocerca volvulus | 0.002 | 0.0129 | 0.0258 | |
Echinococcus granulosus | guanine nucleotide binding protein G protein | 0.0023 | 0.0174 | 0.0213 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.002 | 0.0129 | 0.0158 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0057 | 0.0703 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0445 | 0.6759 | 0.8277 |
Loa Loa (eye worm) | GTP-binding regulatory protein alpha chain | 0.0023 | 0.0174 | 0.0217 |
Brugia malayi | Isocitrate dehydrogenase | 0.0018 | 0.0106 | 0.0132 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0057 | 0.0703 | 0.0914 |
Plasmodium vivax | hypothetical protein, conserved | 0.0032 | 0.0321 | 0.4567 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0092 | 0.1253 | 0.1253 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0677 | 0.0845 |
Toxoplasma gondii | exonuclease III APE | 0.0057 | 0.0703 | 0.3856 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0153 | 0.221 | 0.2758 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0023 | 0.0023 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0023 | 0.0023 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0526 | 0.8012 | 0.9812 |
Onchocerca volvulus | Alhambra homolog | 0.0032 | 0.0321 | 0.0644 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0013 | 0.0023 | 0.0321 |
Echinococcus granulosus | expressed protein | 0.0023 | 0.0174 | 0.0213 |
Schistosoma mansoni | GTP-binding protein alpha subunit gna | 0.0023 | 0.0174 | 0.0213 |
Onchocerca volvulus | 0.002 | 0.0129 | 0.0258 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0174 | 0.0217 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0295 | 0.0369 |
Schistosoma mansoni | hypothetical protein | 0.0445 | 0.6759 | 0.8277 |
Schistosoma mansoni | jumonji domain containing protein | 0.0083 | 0.112 | 0.1372 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0013 | 0.0023 | 0.0043 |
Loa Loa (eye worm) | acetyltransferase | 0.0153 | 0.221 | 0.2758 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0309 | 0.4639 | 0.4639 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0018 | 0.0106 | 0.1506 |
Brugia malayi | Low-density lipoprotein receptor-related protein, putative | 0.002 | 0.0129 | 0.0161 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0013 | 0.0023 | 0.0029 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.0618 | 0.8797 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0505 | 0.7687 | 0.9594 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.002 | 0.0129 | 0.0161 |
Trichomonas vaginalis | G protein (olf) alpha subunit, gnal, putative | 0.0023 | 0.0174 | 0.0226 |
Plasmodium falciparum | thioredoxin reductase | 0.0013 | 0.0023 | 0.0321 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0106 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0174 | 0.0217 |
Loa Loa (eye worm) | guanine nucleotide-binding protein alpha-12 subunit | 0.0023 | 0.0174 | 0.0217 |
Brugia malayi | hypothetical protein | 0.0051 | 0.0618 | 0.0772 |
Echinococcus granulosus | dnaJ subfamily B | 0.0433 | 0.656 | 0.8033 |
Toxoplasma gondii | thioredoxin reductase | 0.0037 | 0.04 | 0.2196 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0013 | 0.0023 | 0.0023 |
Schistosoma mansoni | GTP-binding protein (I) alpha-2 subunit gnai2 | 0.0023 | 0.0174 | 0.0213 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0309 | 0.4639 | 0.4639 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0106 | 0.0106 |
Plasmodium vivax | glutathione reductase, putative | 0.0037 | 0.04 | 0.5696 |
Schistosoma mansoni | ap endonuclease | 0.0057 | 0.0703 | 0.0861 |
Loa Loa (eye worm) | guanine nucleotide-binding protein alpha-6 subunit | 0.0023 | 0.0174 | 0.0217 |
Onchocerca volvulus | 0.0023 | 0.0174 | 0.0349 | |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0032 | 0.0321 | 0.1761 |
Leishmania major | trypanothione reductase | 0.0037 | 0.04 | 0.04 |
Echinococcus multilocularis | Low density lipoprotein receptor, class A, cysteine rich | 0.002 | 0.0129 | 0.0158 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0032 | 0.0321 | 0.1761 |
Echinococcus granulosus | basement membrane specific heparan sulfate | 0.002 | 0.0129 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0211 | 0.3107 | 0.3878 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0013 | 0.0023 | 0.0028 |
Onchocerca volvulus | 0.0023 | 0.0174 | 0.0349 | |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0295 | 0.0362 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0067 | 0.0862 | 0.1055 |
Brugia malayi | CUB domain containing protein | 0.002 | 0.0129 | 0.0161 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0129 | 0.0161 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.002 | 0.0129 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0174 | 0.0217 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0085 | 0.1141 | 0.2201 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.0777 | 0.4262 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0129 | 0.0158 |
Entamoeba histolytica | hypothetical protein | 0.0445 | 0.6759 | 1 |
Schistosoma mansoni | trimeric G-protein alpha o subunit | 0.0023 | 0.0174 | 0.0213 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.4983 | 0.6482 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0057 | 0.0703 | 0.0914 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0045 | 0.0524 | 0.2876 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0433 | 0.656 | 0.8033 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0057 | 0.0703 | 0.0861 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0128 | 0.1823 | 0.3489 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0322 | 0.0395 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0653 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0128 | 0.1823 | 0.3489 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0037 | 0.04 | 0.0772 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0138 | 0.1966 | 0.2454 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0012 | 0.0008 | 0.001 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0057 | 0.0703 | 0.0877 |
Schistosoma mansoni | GTP-binding protein (I) alpha-2 subunit gnai2 | 0.0023 | 0.0174 | 0.0213 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.002 | 0.0129 | 0.0158 |
Trichomonas vaginalis | GTP-binding protein alpha subunit, gna, putative | 0.0023 | 0.0174 | 0.0226 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0085 | 0.1141 | 0.2201 |
Loa Loa (eye worm) | glutathione reductase | 0.0037 | 0.04 | 0.05 |
Trichomonas vaginalis | GTP-binding protein (z) alpha subunit, gnaz, putative | 0.0023 | 0.0174 | 0.0226 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0051 | 0.0618 | 0.3392 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0862 | 0.1055 |
Brugia malayi | CCR4 | 0.0012 | 0.0008 | 0.001 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.002 | 0.0129 | 0.0158 |
Brugia malayi | jmjC domain containing protein | 0.004 | 0.0453 | 0.0565 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0211 | 0.3107 | 0.3878 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0349 | 0.5261 | 0.6843 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Echinococcus multilocularis | low density lipoprotein receptor (ldl) | 0.002 | 0.0129 | 0.0158 |
Echinococcus multilocularis | guanine nucleotide binding protein subunit | 0.0023 | 0.0174 | 0.0213 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0211 | 0.3107 | 0.3878 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0013 | 0.0023 | 0.0023 |
Onchocerca volvulus | 0.002 | 0.0129 | 0.0258 | |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0012 | 0.001 | 0.0012 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0149 | 0.2143 | 0.2624 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0445 | 0.6759 | 0.8277 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0045 | 0.0524 | 0.2876 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0023 | 0.0023 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0057 | 0.0703 | 0.0861 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0057 | 0.0703 | 0.0703 |
Brugia malayi | Guanine nucleotide-binding protein alpha-3 subunit, putative | 0.0023 | 0.0174 | 0.0217 |
Onchocerca volvulus | 0.0023 | 0.0174 | 0.0349 | |
Echinococcus multilocularis | jumonji domain containing protein | 0.0045 | 0.0516 | 0.0632 |
Brugia malayi | hypothetical protein | 0.0445 | 0.6759 | 0.8436 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0041 | 0.0466 | 0.6627 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0174 | 0.0217 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0013 | 0.0023 | 0.0124 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0037 | 0.04 | 0.05 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0128 | 0.1823 | 0.3489 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0336 | 0.042 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0153 | 0.221 | 0.2706 |
Echinococcus multilocularis | peregrin | 0.0036 | 0.038 | 0.0465 |
Toxoplasma gondii | hypothetical protein | 0.0105 | 0.1464 | 0.8029 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0505 | 0.7687 | 1 |
Giardia lamblia | PHD finger protein 15 | 0.0032 | 0.0321 | 0.4567 |
Plasmodium falciparum | glutathione reductase | 0.0037 | 0.04 | 0.5696 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0309 | 0.4639 | 0.4639 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0013 | 0.0023 | 0.0028 |
Schistosoma mansoni | GTP-binding protein (I) alpha-1subunit gnai1 | 0.0023 | 0.0174 | 0.0213 |
Trichomonas vaginalis | GTP-binding protein (O) alpha subunit, gnao, putative | 0.0023 | 0.0174 | 0.0226 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.004 | 0.0453 | 0.0555 |
Brugia malayi | G-protein alpha subunit | 0.0023 | 0.0174 | 0.0217 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0057 | 0.0703 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0085 | 0.1141 | 0.2201 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0045 | 0.0524 | 0.0682 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0174 | 0.0217 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0023 | 0.0023 |
Schistosoma mansoni | hypothetical protein | 0.0536 | 0.8166 | 1 |
Echinococcus granulosus | geminin | 0.0536 | 0.8166 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0862 | 0.1055 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0013 | 0.0023 | 0.0023 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0057 | 0.0703 | 0.0703 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0322 | 0.0395 |
Echinococcus multilocularis | guanine nucleotide binding protein (G protein) | 0.0023 | 0.0174 | 0.0213 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0085 | 0.1141 | 0.2201 |
Loa Loa (eye worm) | low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0129 | 0.0161 |
Brugia malayi | isocitrate dehydrogenase | 0.0018 | 0.0106 | 0.0132 |
Loa Loa (eye worm) | heterotrimeric G protein alpha subunit | 0.0023 | 0.0174 | 0.0217 |
Schistosoma mansoni | GTP-binding protein (I) alpha-2 subunit gnai2 | 0.0023 | 0.0174 | 0.0213 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0129 | 0.0161 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0144 | 0.2068 | 0.2581 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0128 | 0.1823 | 0.1823 |
Echinococcus multilocularis | Low density lipoprotein receptor, class A, cysteine rich | 0.002 | 0.0129 | 0.0158 |
Echinococcus granulosus | guanine nucleotide binding protein subunit | 0.0023 | 0.0174 | 0.0213 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0013 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Trypanosoma brucei | trypanothione reductase | 0.0037 | 0.04 | 0.04 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.004 | 0.0453 | 0.0565 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0013 | 0.0023 | 0.5 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0018 | 0.0106 | 0.0132 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0057 | 0.0703 | 0.0877 |
Onchocerca volvulus | Basement membrane proteoglycan homolog | 0.002 | 0.0129 | 0.0258 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0057 | 0.0703 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0013 | 0.0023 | 0.0028 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0295 | 0.0369 |
Schistosoma mansoni | GTP-binding protein (q) alpha-11 subunit gna11 | 0.0023 | 0.0174 | 0.0213 |
Echinococcus granulosus | jumonji domain containing protein | 0.0045 | 0.0516 | 0.0632 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.0618 | 0.0618 |
Schistosoma mansoni | GTP-binding protein (q) alpha-11 subunit gna11 | 0.0023 | 0.0174 | 0.0213 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0064 | 0.0826 | 0.1011 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.2068 | 0.2532 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0018 | 0.0106 | 0.013 |
Onchocerca volvulus | Terribly reduced optic lobes homolog | 0.002 | 0.0129 | 0.0258 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0505 | 0.7687 | 0.9594 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0013 | 0.0023 | 0.0028 |
Brugia malayi | Guanine nucleotide-binding protein alpha-6 subunit, putative | 0.0023 | 0.0174 | 0.0217 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0013 | 0.0023 | 0.0321 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0032 | 0.0321 | 0.0393 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0129 | 0.0161 |
Trichomonas vaginalis | GTP-binding protein alpha subunit, gna, putative | 0.0023 | 0.0174 | 0.0226 |
Loa Loa (eye worm) | G protein alpha subunit 3 | 0.0023 | 0.0174 | 0.0217 |
Plasmodium falciparum | thioredoxin reductase | 0.0037 | 0.04 | 0.5696 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0129 | 0.0161 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.002 | 0.0129 | 0.0161 |
Onchocerca volvulus | 0.003 | 0.0295 | 0.0593 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.