Detailed information for compound 55168

Basic information

Technical information
  • TDR Targets ID: 55168
  • Name: 3-(3-amino-2-methyl-1,2,4-oxadiazol-2-ium-5-y l)-5-chloropyrazine-2,6-diamine iodide
  • MW: 369.55 | Formula: C7H9ClIN7O
  • H donors: 3 H acceptors: 3 LogP: 1.19 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1nc(N)c(nc1c1nc([n+](o1)C)N)Cl.[I-]
  • InChi: 1S/C7H8ClN7O.HI/c1-15-7(11)14-6(16-15)2-4(9)13-5(10)3(8)12-2;/h1H3,(H5,9,10,11,13,14);1H
  • InChiKey: HCAMWEDSKUNLAF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(3-amino-2-methyl-1,2,4-oxadiazol-2-ium-5-yl)-5-chloro-pyrazine-2,6-diamine iodide
  • 3-(3-azanyl-2-methyl-1,2,4-oxadiazol-2-ium-5-yl)-5-chloro-pyrazine-2,6-diamine iodide
  • [6-amino-3-(3-amino-2-methyl-1,2,4-oxadiazol-2-ium-5-yl)-5-chloro-pyrazin-2-yl]amine iodide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0047 0.0052 0.0355
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0018 0.0117
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0015 0.0011
Trypanosoma brucei C2 domain containing protein, putative 0.0093 0.0144 0.0971
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0068 0.0067
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0243 0.0243
Brugia malayi WW domain containing protein 0.0093 0.0144 0.024
Schistosoma mansoni serine/threonine kinase 0.0754 0.1443 0.1442
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0108 0.0722
Loa Loa (eye worm) hypoxia-induced factor 1 0.015 0.0256 0.0442
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0093 0.0144 0.0991
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0078 0.0114 0.0778
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.002 0.002
Echinococcus multilocularis GPCR, family 2 0.0095 0.0148 0.0144
Echinococcus multilocularis copine 9 0.0093 0.0144 0.0141
Echinococcus granulosus glycine receptor subunit beta 0.0031 0.0023 0.0022
Trichomonas vaginalis DNA polymerase eta, putative 0.0082 0.0122 0.0836
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.029 0.1996
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0025 0.0009 0.004
Brugia malayi MH1 domain containing protein 0.0032 0.0024 0.0039
Brugia malayi PHD-finger family protein 0.003 0.0019 0.0032
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.2295 0.447 0.7731
Trichomonas vaginalis calcium-dependent lipid-binding protein, putative 0.0093 0.0144 0.0987
Trichomonas vaginalis synaptotagmin 1,2, putative 0.0093 0.0144 0.0987
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0005 0.0031
Echinococcus granulosus peroxidasin 0.0052 0.0064 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0024 0.0007 0.0102
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Brugia malayi Variant SH3 domain containing protein 0.01 0.0157 0.0261
Toxoplasma gondii C2 domain-containing protein 0.0093 0.0144 0.0991
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0019
Echinococcus granulosus N chimaerin 0.055 0.1042 0.1041
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Echinococcus granulosus FTZ F1 alpha 0.0048 0.0055 0.0055
Echinococcus multilocularis UNCoordinated family member (unc 13) 0.0093 0.0144 0.0141
Brugia malayi Steroid receptor seven-up type 2 0.0048 0.0055 0.0092
Echinococcus granulosus protein kinase c epsilon type 0.2295 0.447 0.447
Brugia malayi hypothetical protein 0.0025 0.0011 0.0017
Schistosoma mansoni nuclear receptor 0.0023 0.0005 0.0004
Echinococcus multilocularis glycine receptor subunit beta 0.0031 0.0023 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0082 0.0122 0.506
Brugia malayi Nuclear hormone receptor E75 0.0023 0.0005 0.0008
Trypanosoma brucei synaptotagmin, putative 0.0093 0.0144 0.0971
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.0111 0.1669
Trypanosoma cruzi hypothetical protein, conserved 0.0093 0.0144 0.5998
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0055 0.0092
Trichomonas vaginalis chromobox protein, putative 0.0053 0.0065 0.0441
Onchocerca volvulus 0.0093 0.0144 0.0487
Trichomonas vaginalis glutaminase, putative 0.027 0.0491 0.3376
Toxoplasma gondii LsmAD domain-containing protein 0.01 0.0157 0.1081
Brugia malayi Protein kinase domain containing protein 0.0049 0.0057 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0005 0.0031
Plasmodium falciparum glutathione reductase 0.0141 0.0238 1
Echinococcus multilocularis netrin receptor unc 5 0.0032 0.0023 0.0019
Echinococcus granulosus active breakpoint cluster region 0.0093 0.0144 0.0144
Entamoeba histolytica C2 domain containing protein 0.0093 0.0144 0.0812
Echinococcus multilocularis lysosomal alpha glucosidase 0.0351 0.065 0.0647
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0022 0.0004 0.0018
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.0035
Echinococcus multilocularis C2 calcium lipid binding region, CaLB 0.0093 0.0144 0.0141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0048 0.0055 0.0096
Schistosoma mansoni survival motor neuron protein 0.01 0.0157 0.0156
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0084 0.0127 0.0126
Schistosoma mansoni cpg binding protein 0.0097 0.0152 0.0151
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0049 0.0314
Loa Loa (eye worm) glutaminase 0.027 0.0491 0.0848
Loa Loa (eye worm) hypothetical protein 0.0059 0.0076 0.0132
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0024 0.0007 0.0138
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0057 0.2274
Onchocerca volvulus 0.0093 0.0144 0.0487
Schistosoma mansoni lamin 0.0027 0.0014 0.0013
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0033 0.0025 0.0024
Echinococcus multilocularis tar DNA binding protein 0.0201 0.0355 0.0352
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Schistosoma mansoni hypothetical protein 0.0095 0.0148 0.0147
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0049 0.0057 0.1153
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0024 0.0007 0.0138
Entamoeba histolytica hypothetical protein, conserved 0.0093 0.0144 0.0812
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0093 0.0144 0.0971
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0056 0.007 0.0121
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0031 0.0023 0.0037
Trichomonas vaginalis copine, putative 0.0093 0.0144 0.0987
Echinococcus granulosus synaptotagmin protein 4 0.0093 0.0144 0.0144
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0029 0.1079
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.055 0.1042 0.1041
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0137 0.0136
Echinococcus granulosus neuropeptide s receptor 0.1448 0.2806 0.2806
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0074 0.0506
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0031 0.0633
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0117 0.0191 0.1291
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0036 0.0032 0.0028
Schistosoma mansoni neuropeptide receptor 0.0168 0.0291 0.029
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0024 0.0007 0.0102
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Toxoplasma gondii histone lysine methyltransferase SET1 0.0175 0.0305 0.2106
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0245 0.0443 0.0766
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0024 0.0007 0.0138
Echinococcus granulosus unc 13 munc13 0.0641 0.122 0.122
Plasmodium vivax calcium-transporting ATPase, putative 0.0036 0.0032 0.1208
Schistosoma mansoni atypical protein kinase C 0.1302 0.2519 0.2518
Loa Loa (eye worm) hypothetical protein 0.0552 0.1045 0.1807
Plasmodium falciparum nitric oxide synthase, putative 0.0027 0.0013 0.0411
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.055 0.1042 0.1041
Onchocerca volvulus 0.0112 0.0181 0.0613
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0754 0.1443 0.1443
Loa Loa (eye worm) MH2 domain-containing protein 0.047 0.0884 0.1529
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0033 0.0025 0.0149
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0095 0.0148 0.0144
Onchocerca volvulus Putative nachr subunit 0.0031 0.0023 0.0075
Trypanosoma brucei Coiled-coil and C2 domain-containing protein 0.0093 0.0144 0.0971
Echinococcus multilocularis thyroid hormone receptor alpha 0.0048 0.0055 0.0052
Echinococcus multilocularis glycine receptor subunit beta 0.0031 0.0023 0.0019
Echinococcus multilocularis caspase 2 0.0059 0.0076 0.0073
Schistosoma mansoni zinc finger protein 0.0025 0.0009 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0024 0.0007 0.0102
Onchocerca volvulus 0.0025 0.0009 0.0031
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0025 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0005 0.0031
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0093 0.0144 0.7464
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.0009 0.0009
Trypanosoma brucei glycosyl hydrolase-like protein 0.0029 0.0018 0.0098
Entamoeba histolytica calcium-binding protein, putative 0.0093 0.0144 0.0812
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0022 0.0143
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Trichomonas vaginalis pc-MYB2, putative 0.0047 0.0052 0.0355
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Schistosoma mansoni smad 0.0032 0.0024 0.0023
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0057 0.2274
Schistosoma mansoni lozenge 0.0055 0.007 0.0069
Loa Loa (eye worm) C2 domain-containing protein 0.0093 0.0144 0.0249
Leishmania major hypothetical protein, conserved 0.0093 0.0144 0.4482
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.029 0.1996
Echinococcus multilocularis extended synaptotagmin 2 0.0093 0.0144 0.0141
Echinococcus granulosus neuropeptide receptor A26 0.1448 0.2806 0.2806
Brugia malayi hypothetical protein 0.01 0.0157 0.0261
Brugia malayi polk-prov protein 0.0044 0.0047 0.0077
Loa Loa (eye worm) hypothetical protein 0.0489 0.0921 0.1592
Leishmania major hypothetical protein, conserved 0.0093 0.0144 0.4482
Echinococcus multilocularis calpain 5 0.0093 0.0144 0.0141
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0036 0.0032 0.0643
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.0005 0.0017
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0355 0.0354
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0114 0.0778
Loa Loa (eye worm) hypothetical protein 0.0548 0.1037 0.1793
Trypanosoma cruzi hypothetical protein, conserved 0.0093 0.0144 0.5998
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Echinococcus multilocularis synaptotagmin 0.0093 0.0144 0.0141
Brugia malayi Pre-SET motif family protein 0.0062 0.0082 0.0137
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0031 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.002 0 0.0001
Onchocerca volvulus 0.0031 0.0023 0.0075
Loa Loa (eye worm) MH1 domain-containing protein 0.0032 0.0024 0.0041
Trypanosoma cruzi synaptotagmin, putative 0.0093 0.0144 0.5998
Loa Loa (eye worm) CXXC zinc finger family protein 0.009 0.0138 0.0238
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0355 0.0354
Loa Loa (eye worm) hypothetical protein 0.0654 0.1245 0.2154
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0027 0.0013 0.0013
Loa Loa (eye worm) CAMK/PKD protein kinase 0.014 0.0236 0.0409
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0005 0.0028
Echinococcus multilocularis protein kinase c iota type 0.1302 0.2519 0.2516
Plasmodium vivax P-type ATPase4, putative 0.0036 0.0032 0.1208
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0024 0.0007 0.0138
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0031 0.0023 0.0022
Entamoeba histolytica protein kinase, putative 0.0111 0.0179 0.1007
Schistosoma mansoni patched 1 0.0041 0.0041 0.004
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0021 0.0003 0.0008
Onchocerca volvulus Peroxidasin homolog 0.0052 0.0064 0.0214
Echinococcus granulosus calcium transporting atpase 0.0025 0.0009 0.0009
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0018 0.0117
Schistosoma mansoni hypothetical protein 0.0133 0.0223 0.0222
Schistosoma mansoni Mername-AA248 (C02 family) 0.0093 0.0144 0.0143
Trypanosoma cruzi PAB1-binding protein , putative 0.01 0.0157 0.6551
Trypanosoma cruzi Coiled-coil and C2 domain-containing protein 0.0093 0.0144 0.5998
Echinococcus multilocularis protein kinase c epsilon type 0.2295 0.447 0.4468
Trypanosoma cruzi C2 domain/Ankyrin repeats (3 copies), putative 0.0093 0.0144 0.5998
Trypanosoma cruzi cytoskeleton associated protein, putative 0.0093 0.0144 0.5998
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0025 0.0009 0.0059
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0027 0.0013 0.001
Brugia malayi Synaptotagmin I 0.0093 0.0144 0.024
Echinococcus multilocularis Diacylglycerol kinase theta 0.0548 0.1037 0.1034
Echinococcus granulosus Chromo domain 0.0023 0.0005 0.0005
Echinococcus granulosus C2 calcium lipid binding region CaLB 0.0093 0.0144 0.0144
Entamoeba histolytica hypothetical protein 0.0093 0.0144 0.0812
Trichomonas vaginalis chromobox protein, putative 0.008 0.0119 0.0812
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0022 0.0021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0005 0.0005
Schistosoma mansoni diacylglycerol kinase theta 0.0548 0.1037 0.1036
Echinococcus granulosus Smad4 0.0032 0.0024 0.0023
Toxoplasma gondii target of rapamycin (TOR), putative 0.0073 0.0104 0.0709
Loa Loa (eye worm) C2 domain-containing protein 0.0093 0.0144 0.0249
Schistosoma mansoni bromodomain containing protein 0.0068 0.0094 0.0093
Leishmania major cathepsin L-like protease 0.0075 0.0108 0.3333
Echinococcus granulosus synaptotagmin 15 0.0093 0.0144 0.0144
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.0005 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0117 0.0191 0.1307
Echinococcus multilocularis synaptotagmin 0.0093 0.0144 0.0141
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0759 0.1451 1
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0031 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0011 0.0017
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0117 0.0191 0.1312
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0031 0.0023 0.0022
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0025 0.0009 0.025
Plasmodium vivax hypothetical protein, conserved 0.0093 0.0144 0.5998
Echinococcus multilocularis serine threonine protein kinase 0.3263 0.6371 0.637
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0048 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0025 0.0009 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0098 0.0153 0.1046
Loa Loa (eye worm) hypothetical protein 0.0048 0.0055 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Brugia malayi Hr1 repeat family protein 0.0754 0.1443 0.2405
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0023 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0206 0.0365 0.0632
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0027 0.0013 0.0411
Echinococcus multilocularis multiple C2 and transmembrane domain containing protein 0.0093 0.0144 0.0141
Loa Loa (eye worm) hypothetical protein 0.0048 0.0055 0.0096
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0108 0.0722
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Brugia malayi CHD4 protein 0.003 0.0019 0.0031
Loa Loa (eye worm) STAT protein 0.0131 0.0219 0.0378
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0031 0.0023 0.0019
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0049 0.0057 0.2274
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Brugia malayi Muscleblind-like protein 0.0654 0.1245 0.2075
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0243 0.0243
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0031 0.0023 0.0039
Loa Loa (eye worm) histone methyltransferase 0.003 0.002 0.0035
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0022 0.0583
Entamoeba histolytica C2 domain containing protein 0.0093 0.0144 0.0812
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0027 0.0013 0.0263
Brugia malayi RhoGEF domain containing protein 0.0548 0.1037 0.1727
Schistosoma mansoni hypothetical protein 0.0039 0.0038 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0104 0.0707
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0463 0.3187
Onchocerca volvulus 0.0103 0.0163 0.055
Trichomonas vaginalis CMGC family protein kinase 0.0117 0.0191 0.1307
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0141 0.0238 0.3583
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0113 0.0775
Schistosoma mansoni synaptotagmin 12 0.0093 0.0144 0.0143
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0093 0.0144 0.0144
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0024 0.0007 0.0102
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0093 0.0144 0.0144
Loa Loa (eye worm) C2 domain-containing protein 0.0093 0.0144 0.0249
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0093 0.0144 0.0141
Loa Loa (eye worm) hypothetical protein 0.0548 0.1037 0.1793
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0057 0.2274
Entamoeba histolytica C2 domain containing protein 0.0093 0.0144 0.0812
Echinococcus granulosus nAChR subunit 0.0031 0.0023 0.0022
Trypanosoma brucei trypanothione reductase 0.0141 0.0238 0.1619
Loa Loa (eye worm) hypothetical protein 0.0048 0.0055 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0113 0.0775
Loa Loa (eye worm) hypothetical protein 0.0079 0.0116 0.02
Brugia malayi Pleckstrin Homology Domain 0.0552 0.1045 0.1741
Trypanosoma cruzi major cysteine proteinase, putative 0.0059 0.0077 0.3115
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0641 0.122 0.1217
Entamoeba histolytica protein kinase, putative 0.0759 0.1451 0.8192
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0033 0.0025 0.0025
Trichomonas vaginalis AGC family protein kinase 0.0759 0.1451 1
Trypanosoma brucei predicted C2 domain protein 0.0093 0.0144 0.0971
Echinococcus granulosus mitogen activated protein kinase 3 0.0117 0.0191 0.019
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0048 0.0055 0.0055
Schistosoma mansoni cytochrome P450 reductase 0.0027 0.0013 0.0012
Echinococcus multilocularis muscleblind protein 1 0.0654 0.1245 0.1242
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0048 0.0055 0.0092
Loa Loa (eye worm) hypothetical protein 0.005 0.0059 0.0102
Echinococcus multilocularis neuropeptide receptor A26 0.1448 0.2806 0.2804
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0048 0.0055 0.0096
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0114 0.0778
Entamoeba histolytica hypothetical protein 0.0093 0.0144 0.0812
Onchocerca volvulus Transcription factor Sp5 homolog 0.0353 0.0654 0.2215
Brugia malayi ImpB/MucB/SamB family protein 0.0056 0.007 0.0116
Brugia malayi beta-NAC-like protein 0.0035 0.0029 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Brugia malayi Glycosyl hydrolases family 31 protein 0.0351 0.065 0.1083
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0024 0.0007 0.0102
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0005 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0024 0.0007 0.0102
Schistosoma mansoni aldehyde dehydrogenase 0.0181 0.0317 0.0316
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0031 0.0023 0.0022
Leishmania major c2 domain protein, putative 0.0093 0.0144 0.4482
Echinococcus multilocularis raf serine:threonine protein kinase 0.0548 0.1037 0.1034
Brugia malayi Variant SH3 domain containing protein 0.055 0.1042 0.1736
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0048 0.0055 0.0055
Trypanosoma brucei unspecified product 0.0038 0.0036 0.0225
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.009 0.061
Onchocerca volvulus 0.0048 0.0055 0.0186
Brugia malayi isocitrate dehydrogenase 0.0031 0.0022 0.0036
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0031 0.0023 0.0019
Trichomonas vaginalis C-MYB, putative 0.0047 0.0052 0.0355
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0068 0.0095 0.3915
Brugia malayi Protein kinase domain containing protein 0.0754 0.1443 0.2405
Brugia malayi Animal haem peroxidase family protein 0.0052 0.0064 0.0105
Echinococcus granulosus smad 0.0032 0.0024 0.0023
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Schistosoma mansoni transcription factor LCR-F1 0.0339 0.0626 0.0625
Loa Loa (eye worm) hypothetical protein 0.0548 0.1037 0.1793
Onchocerca volvulus 0.0093 0.0144 0.0487
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0024 0.0882
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0031 0.0023 0.0022
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0152 0.0259 0.8144
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0036 0.0031 0.0052
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0093 0.0144 0.0141
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0024 0.0007 0.0102
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0093 0.0144 0.0249
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0019
Brugia malayi Bromodomain containing protein 0.0038 0.0035 0.0058
Schistosoma mansoni synaptotagmin 0.0093 0.0144 0.0143
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0023 0.0005 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.029 0.1996
Echinococcus granulosus synaptotagmin 0.0093 0.0144 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Echinococcus granulosus SAM and MBT domain containing protein 0.0054 0.0068 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0048 0.0055 0.0092
Schistosoma mansoni aldehyde dehydrogenase 0.0181 0.0317 0.0316
Brugia malayi nuclear hormone receptor 0.0048 0.0055 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0463 0.3187
Brugia malayi latrophilin 2 splice variant baaae 0.0206 0.0365 0.0608
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0047 0.0053 0.0358
Echinococcus multilocularis mitogen activated protein kinase 3 0.0117 0.0191 0.0187
Onchocerca volvulus Peroxidase homolog 0.0052 0.0064 0.0214
Loa Loa (eye worm) hypothetical protein 0.067 0.1277 0.2209
Onchocerca volvulus 0.0052 0.0064 0.0214
Echinococcus multilocularis 0.0024 0.0007 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0548 0.1037 0.1036
Mycobacterium ulcerans DNA polymerase IV 0.0082 0.0122 0.2485
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.009 0.0137 0.0133
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0022 0.0781
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0025 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Echinococcus multilocularis mothers against decapentaplegic 5 0.0032 0.0024 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.0122 0.0819
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Echinococcus multilocularis thioredoxin glutathione reductase 0.0141 0.0238 0.0234
Entamoeba histolytica diacylglycerol kinase, putative 0.0548 0.1037 0.5852
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0117 0.0191 0.596
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0688 0.1312 0.2186
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Trichomonas vaginalis CMGC family protein kinase 0.0117 0.0191 0.1307
Entamoeba histolytica C2 domain protein, putative 0.0093 0.0144 0.0812
Onchocerca volvulus 0.003 0.002 0.0068
Brugia malayi RNA recognition motif domain containing protein 0.0201 0.0355 0.0591
Loa Loa (eye worm) CHromoDomain protein family member 0.003 0.0019 0.0033
Brugia malayi nuclear receptor NHR-67 0.0023 0.0005 0.0008
Loa Loa (eye worm) nuclear hormone receptor 0.0023 0.0005 0.0009
Leishmania major phosphatidylinositol 3-kinase, putative 0.0033 0.0025 0.0688
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0024 0.0007 0.0102
Brugia malayi Thioredoxin reductase 0.0141 0.0238 0.0396
Echinococcus multilocularis chromobox protein 1 0.008 0.0119 0.0115
Toxoplasma gondii protein kinase domain-containing protein 0.0022 0.0004 0.0016
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0093 0.0144 0.0987
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.0122 0.0819
Onchocerca volvulus 0.0103 0.0163 0.055
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0007 0.015
Echinococcus granulosus Immunoglobulin E set 0.0093 0.0144 0.0144
Echinococcus multilocularis cpg binding protein 0.0097 0.0152 0.0148
Loa Loa (eye worm) AGC/AKT protein kinase 0.0759 0.1451 0.251
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0032 0.0023 0.0022
Echinococcus granulosus thyroid hormone receptor alpha 0.0023 0.0005 0.0005
Brugia malayi Animal haem peroxidase family protein 0.0052 0.0064 0.0105
Trypanosoma cruzi cAMP binding protein, putative 0.0093 0.0144 0.5998
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0019
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0079 0.0116 0.0112
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0093 0.0144 0.0143
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0104 0.0707
Brugia malayi Cell death protein 3 precursor 0.0059 0.0076 0.0126
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0025 0.0009 0.0059
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0032 0.0024 0.0023
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0097 0.0151 0.015
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0041 0.0071
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0049 0.0057 0.1153
Entamoeba histolytica p21-activated kinase 0.0022 0.0004 0.0018
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0048 0.0055 0.0096
Entamoeba histolytica PH domain containing protein kinase, putative 0.0022 0.0004 0.0018
Brugia malayi MH1 domain containing protein 0.0032 0.0024 0.0039
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.0009 0.0006
Echinococcus granulosus glycine receptor subunit beta 0.0031 0.0023 0.0022
Schistosoma mansoni transcription factor btf3 0.0035 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0057 0.2274
Echinococcus granulosus Ankyrin repeat domain containing protein 0.009 0.0137 0.0137
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0048 0.0055 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0108 0.0722
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0041 0.0041
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0025 0.0009 0.0051
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0014 0.0022
Schistosoma mansoni hypothetical protein 0.0548 0.1037 0.1036
Echinococcus multilocularis Chromobox protein 3 0.0023 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Brugia malayi CHE-14 protein 0.0041 0.0041 0.0068
Schistosoma mansoni synaptotagmin 0.0093 0.0144 0.0143
Leishmania major basic transcription factor 3a, putative 0.0035 0.0029 0.0806
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0005 0.0004
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0322 0.0593 0.8936
Entamoeba histolytica hypothetical protein 0.0548 0.1037 0.5852
Mycobacterium ulcerans aldehyde dehydrogenase 0.0181 0.0317 0.6463
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0355 0.0354
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0093 0.0144 0.024
Echinococcus multilocularis nuclear receptor nhr 48 0.0023 0.0005 0.0002
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0024 0.0007 0.0138
Echinococcus multilocularis serine:threonine protein kinase N2 0.1654 0.3211 0.3208
Plasmodium falciparum calcium-transporting ATPase 0.0025 0.0009 0.0232
Schistosoma mansoni cellular tumor antigen P53 0.0101 0.0159 0.0158
Schistosoma mansoni zinc finger protein 0.0023 0.0005 0.0004
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0025 0.0011 0.0019
Schistosoma mansoni smad1 5 8 and 0.0032 0.0024 0.0023
Leishmania major cathepsin L-like protease 0.0075 0.0108 0.3333
Plasmodium vivax glutathione reductase, putative 0.0141 0.0238 1
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0048 0.0055 0.0096
Echinococcus multilocularis dnaJ subfamily B 0.1282 0.248 0.2477
Schistosoma mansoni thyroid hormone receptor 0.0048 0.0055 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0061
Echinococcus granulosus RNA directed DNA polymerase 0.2416 0.4706 0.4706
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Echinococcus multilocularis jun protein 0.0164 0.0283 0.0279
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0024 0.0007 0.0138
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0025 0.0011 0.001
Trypanosoma brucei C2 domain/Ankyrin repeats (3 copies), putative 0.0093 0.0144 0.0971
Echinococcus granulosus protein kinase c iota type 0.1302 0.2519 0.2519
Leishmania major hypothetical protein, conserved 0.0093 0.0144 0.4482
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Schistosoma mansoni RAR-like nuclear receptor 0.0048 0.0055 0.0054
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0057 0.2274
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Schistosoma mansoni synaptotagmin 0.0093 0.0144 0.0143
Loa Loa (eye worm) hypothetical protein 0.1523 0.2953 0.5107
Trypanosoma cruzi hypothetical protein, conserved 0.0093 0.0144 0.5998
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0005 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0093 0.0144 0.5998
Loa Loa (eye worm) hypothetical protein 0.0442 0.0828 0.1433
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0047 0.0052 0.0355
Echinococcus granulosus NDR protein kinase 0.0754 0.1443 0.1443
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.01 0.0157 0.026
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0023 0.0037
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.055 0.1042 0.1038
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0027 0.0179
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Onchocerca volvulus 0.0052 0.0064 0.0214
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.0148 0.0144
Loa Loa (eye worm) hypothetical protein 0.0123 0.0202 0.0349
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0024 0.0007 0.0102
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0078 0.0114 0.0197
Brugia malayi Cytochrome P450 family protein 0.0068 0.0094 0.0157
Echinococcus multilocularis polycomb protein SCMH1 0.0054 0.0068 0.0064
Echinococcus multilocularis chromobox protein 2 0.0023 0.0005 0.0002
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0029 0.1079
Trichomonas vaginalis synaptotagmin, putative 0.0093 0.0144 0.0987
Loa Loa (eye worm) hypothetical protein 0.0163 0.0281 0.0485
Schistosoma mansoni protein kinase C 0.0641 0.122 0.1219
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0565 0.1071 0.1071
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0215 0.0383 0.0379
Leishmania major trypanothione reductase 0.0141 0.0238 0.7473
Echinococcus multilocularis expressed conserved protein 0.009 0.0137 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0064 0.0436
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0057 0.0368
Echinococcus granulosus UNCoordinated family member unc 13 0.0093 0.0144 0.0144
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0025 0.0009 0.0051
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0098 0.0153 0.1029
Schistosoma mansoni microtubule-associated protein tau 0.511 1 1
Entamoeba histolytica hypothetical protein 0.0339 0.0626 0.3534
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0093 0.0144 0.0143
Onchocerca volvulus Huntingtin homolog 0.0241 0.0434 0.1469
Echinococcus multilocularis synaptotagmin 0.0093 0.0144 0.0141
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0001 0.0002
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0164 0.0283 0.0279
Brugia malayi RhoGAP domain containing protein 0.0548 0.1037 0.1727
Echinococcus multilocularis synaptotagmin 2 0.0093 0.0144 0.0141
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.0243 0.042
Trichomonas vaginalis AGC family protein kinase 0.0759 0.1451 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0023 0.0037
Echinococcus granulosus lysosomal alpha glucosidase 0.0351 0.065 0.065
Entamoeba histolytica protein kinase, putative 0.0754 0.1443 0.8146
Schistosoma mansoni chromobox protein 0.008 0.0119 0.0118
Echinococcus granulosus Protein kinase C brain isozyme 0.3811 0.7447 0.7447
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0031 0.0023 0.0037
Brugia malayi Zinc finger, C2H2 type family protein 0.0353 0.0654 0.109
Loa Loa (eye worm) hypothetical protein 0.2416 0.4706 0.8139
Echinococcus multilocularis synaptotagmin 0.0093 0.0144 0.0141
Trypanosoma brucei predicted C2 domain protein 0.0093 0.0144 0.0971
Loa Loa (eye worm) hypothetical protein 0.2963 0.5782 1
Brugia malayi ImpB/MucB/SamB family protein 0.0056 0.007 0.0116
Trichomonas vaginalis chromobox protein, putative 0.008 0.0119 0.0812
Echinococcus granulosus neutral alpha glucosidase AB 0.0078 0.0114 0.0113
Trichomonas vaginalis AGC family protein kinase 0.0754 0.1443 0.9944
Echinococcus multilocularis intersectin 2 0.0093 0.0144 0.0141
Loa Loa (eye worm) hypothetical protein 0.0548 0.1037 0.1793
Trypanosoma cruzi C2 domain containing protein, putative 0.0093 0.0144 0.5998
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0055 0.0052
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0031 0.0023 0.0022
Trypanosoma brucei calcium-translocating P-type ATPase 0.0025 0.0009 0.0038
Loa Loa (eye worm) RasGEF domain-containing protein 0.0548 0.1037 0.1793
Schistosoma mansoni chromobox protein 0.0023 0.0005 0.0004
Entamoeba histolytica hypothetical protein 0.0023 0.0005 0.0028
Brugia malayi nuclear hormone receptor 0.0023 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0548 0.1037 0.1793
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0027 0.0013 0.0411
Schistosoma mansoni hypothetical protein 0.0095 0.0148 0.0147
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0031 0.0023 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0074 0.0506
Echinococcus multilocularis Chromo domain 0.0023 0.0005 0.0002
Onchocerca volvulus 0.0674 0.1286 0.4353
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0019
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.0111 0.1669
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0015 0.0014
Toxoplasma gondii AGC kinase 0.0754 0.1443 1
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Brugia malayi RhoGAP domain containing protein 0.055 0.1042 0.1736
Loa Loa (eye worm) cytochrome P450 0.0024 0.0007 0.0012
Entamoeba histolytica C2 domain containing protein 0.0093 0.0144 0.0812
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0031 0.0023 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0098 0.0153 0.1046
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0301 0.0552 0.0955
Trichomonas vaginalis sulfite reductase, putative 0.0027 0.0013 0.0085
Echinococcus multilocularis survival motor neuron protein 1 0.0489 0.0921 0.0917
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0024 0.0007 0.015
Schistosoma mansoni hypothetical protein 0.0023 0.0005 0.0004
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Brugia malayi hypothetical protein 0.0489 0.0921 0.1534
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Echinococcus granulosus transcription factor btf3 0.0035 0.0029 0.0028
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0049 0.0057 0.1153
Brugia malayi hypothetical protein 0.0442 0.0828 0.138
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.029 0.0983
Loa Loa (eye worm) hypothetical protein 0.0044 0.0047 0.0081
Echinococcus multilocularis SAM and MBT domain containing protein 0.0054 0.0068 0.0064
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0029 0.0018 0.0608
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0033 0.0025 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0243 0.0242
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0737 0.1408 0.9705
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Schistosoma mansoni chromodomain helicase DNA binding protein 0.003 0.0019 0.0018
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0256 0.0463 0.0801
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0308 0.0567 0.0563
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.0122 0.0819
Giardia lamblia GTOR 0.0098 0.0153 0.7933
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0027 0.0013 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.0754 0.1443 0.1442
Echinococcus granulosus geminin 0.0854 0.1639 0.1638
Echinococcus granulosus chromobox protein 1 0.008 0.0119 0.0118
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0181 0.0317 0.4778
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0031 0.0023 0.0022
Echinococcus granulosus caspase 2 0.0059 0.0076 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0048 0.0055 0.0096
Onchocerca volvulus Multiple C2 domain and transmembrane region protein homolog 0.0093 0.0144 0.0487
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0754 0.1443 0.144
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0024 0.0007 0.0138
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.0111 0.0184
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0201 0.0355 0.0614
Echinococcus granulosus intersectin 2 0.0093 0.0144 0.0144
Brugia malayi Nuclear hormone receptor E75 0.0023 0.0005 0.0008
Loa Loa (eye worm) TAR-binding protein 0.0201 0.0355 0.0614
Toxoplasma gondii hypothetical protein 0.0093 0.0144 0.0991
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0022 0.0126
Trypanosoma cruzi trypanothione reductase, putative 0.0141 0.0238 1
Loa Loa (eye worm) blistered cuticle protein 3 0.0052 0.0064 0.011
Echinococcus multilocularis ecdysone induced protein 78C 0.0048 0.0055 0.0052
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0047 0.0052 0.0294
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0031 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Echinococcus multilocularis mitogen activated protein kinase 0.0117 0.0191 0.0187
Echinococcus granulosus thioredoxin glutathione reductase 0.0141 0.0238 0.0238
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0049 0.0057 0.0056
Brugia malayi LD23056p 0.0093 0.0144 0.024
Schistosoma mansoni nAChR subunit 0.0031 0.0023 0.0022
Toxoplasma gondii thioredoxin reductase 0.0141 0.0238 0.1641
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.029 0.1996
Trichomonas vaginalis AGC family protein kinase 0.0754 0.1443 0.9944
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0041 0.0041 0.0255
Trichomonas vaginalis annexin VII, putative 0.0093 0.0144 0.0987
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0023 0.0005 0.0008
Onchocerca volvulus 0.0103 0.0163 0.055
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0024 0.0007 0.0138
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0048 0.0055 0.0092
Loa Loa (eye worm) hypothetical protein 0.0041 0.0041 0.0071
Onchocerca volvulus 0.0041 0.0042 0.014
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Echinococcus granulosus Diacylglycerol kinase theta 0.0548 0.1037 0.1036
Plasmodium vivax flavodoxin domain containing protein 0.0024 0.0007 0.0157
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0031 0.0023 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0104 0.0707
Schistosoma mansoni peroxidasin 0.0052 0.0064 0.0063
Onchocerca volvulus Bile acid receptor homolog 0.0048 0.0055 0.0186
Echinococcus multilocularis neuropeptide receptor 0.0168 0.0291 0.0287
Brugia malayi intermediate filament protein 0.0027 0.0014 0.0022
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0022 0.0325
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0036 0.0032 0.0031
Echinococcus granulosus glycine receptor subunit alpha 1 0.0031 0.0023 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0759 0.1451 1
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0031 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0322 0.0593 0.8936
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.0018 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0095
Brugia malayi hypothetical protein 0.0041 0.0042 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0049 0.0057 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0029 0.0193
Echinococcus granulosus serine/threonine protein kinase 0.0022 0.0004 0.0003
Trichomonas vaginalis synaptotagmin 1, 3, C.elegans, putative 0.0093 0.0144 0.0987
Mycobacterium ulcerans aldehyde dehydrogenase 0.0181 0.0317 0.6463
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0025 0.0009 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0308 0.2119
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0031 0.0023 0.0019
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0025 0.0009 0.0008
Loa Loa (eye worm) animal heme peroxidase 0.0052 0.0064 0.011
Onchocerca volvulus 0.0023 0.0005 0.0017
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0046 0.0052 0.0331
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0031 0.0023 0.0019
Brugia malayi diacylglycerol kinase 0.0548 0.1037 0.1727
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0055 0.0092
Echinococcus multilocularis RNA directed DNA polymerase 0.2416 0.4706 0.4704
Leishmania major hypothetical protein, conserved 0.0093 0.0144 0.4482
Loa Loa (eye worm) ACC-1 protein 0.0031 0.0023 0.0039
Brugia malayi hypothetical protein 0.0025 0.0011 0.0017
Brugia malayi Cation transporter family protein 0.0103 0.0163 0.0271
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Leishmania major hypothetical protein, conserved 0.0093 0.0144 0.4482
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0046 0.0307
Schistosoma mansoni serine/threonine protein kinase 0.0565 0.1071 0.107
Echinococcus multilocularis FTZ F1 alpha 0.0048 0.0055 0.0052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0055 0.0092
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0068 0.0067
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0047 0.0053 0.0358
Brugia malayi Animal haem peroxidase family protein 0.0052 0.0064 0.0105
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0005 0.0077
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Loa Loa (eye worm) DR-78 0.0023 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0123 0.0202 0.0349
Schistosoma mansoni hypothetical protein 0.0093 0.0144 0.0143
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0419 0.0785 0.1357
Schistosoma mansoni synaptotagmin 0.0093 0.0144 0.0143
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0031 0.0023 0.0022
Mycobacterium tuberculosis Probable reductase 0.0322 0.0593 0.8936
Entamoeba histolytica hypothetical protein 0.0035 0.0029 0.0161
Brugia malayi hypothetical protein 0.0023 0.0005 0.0008
Entamoeba histolytica C2 domain containing protein 0.0093 0.0144 0.0812
Echinococcus granulosus histone lysine methyltransferase setb 0.0079 0.0116 0.0115
Trypanosoma cruzi PAB1-binding protein , putative 0.01 0.0157 0.6551
Schistosoma mansoni nuclear receptor 0.0023 0.0005 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0104 0.0707
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0023 0.0037
Echinococcus granulosus neural cell expressed developmentally 0.0093 0.0144 0.0144
Toxoplasma gondii P-type ATPase4, putative 0.0025 0.0009 0.0057
Trichomonas vaginalis synaptotagmin, putative 0.0093 0.0144 0.0987
Loa Loa (eye worm) hypothetical protein 0.0076 0.0111 0.0192
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0024 0.0007 0.0024
Loa Loa (eye worm) runx1 0.0055 0.007 0.0121
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0152 0.0259 0.0259
Toxoplasma gondii hypothetical protein 0.0093 0.0144 0.0991
Schistosoma mansoni serine/threonine-protein kinase 0.0022 0.0004 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0048 0.0055 0.0092
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0754 0.1443 0.1443
Brugia malayi hypothetical protein 0.0129 0.0214 0.0356
Echinococcus granulosus polycomb protein SCMH1 0.0054 0.0068 0.0067
Schistosoma mansoni synaptotagmin 0.0093 0.0144 0.0143
Echinococcus granulosus cytochrome P450 2K1 0.0024 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0113 0.0775
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0322 0.0593 0.8936
Echinococcus granulosus copine 9 0.0093 0.0144 0.0144
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0023 0.0005 0.0009
Onchocerca volvulus 0.0093 0.0144 0.0487
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0048 0.0055 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.0122 0.0819
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0093 0.0144 0.5998
Schistosoma mansoni hypothetical protein 0.0039 0.0038 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0048 0.0055 0.0092
Entamoeba histolytica PH domain containing protein kinase, putative 0.0922 0.1771 1
Mycobacterium ulcerans glutaminase 0.027 0.0491 1
Echinococcus granulosus lamin dm0 0.0027 0.0014 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0048 0.0055 0.0092
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Schistosoma mansoni hypothetical protein 0.0045 0.0049 0.0048
Onchocerca volvulus 0.0084 0.0127 0.0428
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0229 0.0225
Brugia malayi hypothetical protein 0.0052 0.0064 0.0105
Trypanosoma cruzi cysteine peptidase, putative 0.0075 0.0108 0.446
Schistosoma mansoni serine/threonine protein kinase 0.0565 0.1071 0.107
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0024 0.0882
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0093 0.0144 0.0143
Onchocerca volvulus 0.0031 0.0023 0.0075
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0019
Trichomonas vaginalis copine, putative 0.0093 0.0144 0.0987
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0025 0.0167
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0111 0.4584
Trichomonas vaginalis synaptotagmin 1,2, putative 0.0093 0.0144 0.0987
Trichomonas vaginalis hypothetical protein 0.0023 0.0005 0.0031
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0098 0.0153 0.1029
Brugia malayi RNA binding protein 0.0201 0.0355 0.0591
Echinococcus multilocularis multiple C2 and transmembrane domain containing protein 0.0093 0.0144 0.0141
Onchocerca volvulus 0.0146 0.0248 0.084
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0117 0.0191 0.7975
Leishmania major alpha glucosidase II subunit, putative 0.0078 0.0114 0.3516
Brugia malayi follicle stimulating hormone receptor 0.0245 0.0443 0.0738
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0108 0.0722
Brugia malayi nuclear receptor RXR 0.0023 0.0005 0.0008
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0024 0.0007 0.0044
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0018 0.0117
Brugia malayi nuclear receptor NHR-88 0.0048 0.0055 0.0092
Loa Loa (eye worm) hypothetical protein 0.0048 0.0055 0.0096
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Echinococcus granulosus chromobox protein 2 0.0023 0.0005 0.0005
Schistosoma mansoni mctp-related 0.0093 0.0144 0.0143
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0193 0.034 0.0339
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0024 0.0007 0.0138
Brugia malayi Glycosyl hydrolases family 31 protein 0.0029 0.0018 0.0029
Loa Loa (eye worm) Nedd4-PD 0.0093 0.0144 0.0249
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0005 0.0028
Schistosoma mansoni protein kinase C mu 0.0548 0.1037 0.1036
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0148 0.0145
Brugia malayi Cytochrome P450 family protein 0.0032 0.0024 0.004
Echinococcus multilocularis myoferlin 0.0093 0.0144 0.0141
Echinococcus granulosus dna polymerase eta 0.0056 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0095 0.0148 0.0148
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0108 0.0722
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0025 0.0009 0.0014
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0029 0.0191
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0339 0.0626 0.0623
Schistosoma mansoni serine/threonine protein kinase 0.2295 0.447 0.4469
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0022 0.0018
Trichomonas vaginalis mercuric reductase, putative 0.0049 0.0057 0.0386
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0548 0.1037 0.1793
Schistosoma mansoni cpg binding protein 0.0097 0.0152 0.0151
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0062 0.0083 0.0137
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0049 0.0057 0.0053
Echinococcus multilocularis muscleblind protein 0.0654 0.1245 0.1242
Trichomonas vaginalis synaptotagmin, putative 0.0093 0.0144 0.0987
Brugia malayi NEDD4.2 0.0093 0.0144 0.024
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0114 0.4705
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0093 0.0144 0.014
Onchocerca volvulus Peroxidase homolog 0.0052 0.0064 0.0214
Echinococcus multilocularis Rac GTPase activating protein 1 0.0548 0.1037 0.1034
Schistosoma mansoni nAChR subunit 0.0031 0.0023 0.0022
Brugia malayi Death domain containing protein 0.0032 0.0023 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Schistosoma mansoni hypothetical protein 0.0854 0.1639 0.1638
Loa Loa (eye worm) variant SH3 domain-containing protein 0.01 0.0157 0.0272
Echinococcus multilocularis lamin dm0 0.0027 0.0014 0.001
Brugia malayi Protein kinase c protein 2 0.3074 0.6 1
Schistosoma mansoni rab3 interacting molecule (rim)-related 0.0093 0.0144 0.0143
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.0122 0.0819
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0005 0.0004
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0005 0.0028
Brugia malayi Valyl-tRNA synthetase 0.0023 0.0005 0.0008
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0098 0.0153 0.636
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0025 0.0009 0.0187
Brugia malayi hypothetical protein 0.0087 0.0132 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.0122 0.0819
Echinococcus multilocularis lamin 0.0027 0.0014 0.001
Loa Loa (eye worm) hypothetical protein 0.0062 0.0083 0.0143
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0114 0.0778
Echinococcus granulosus C2 calcium lipid binding region CaLB 0.0093 0.0144 0.0144
Loa Loa (eye worm) SPTF-3 protein 0.0353 0.0654 0.1132
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.029 0.1996
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0005 0.0002
Schistosoma mansoni retinoic acid receptor RXR 0.0048 0.0055 0.0054
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0164 0.0283 0.0282
Schistosoma mansoni nuclear receptor nhr-48 0.0023 0.0005 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Entamoeba histolytica PH domain containing protein kinase, putative 0.0022 0.0004 0.0018
Entamoeba histolytica hypothetical protein 0.0339 0.0626 0.3534
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0031 0.0023 0.0037
Schistosoma mansoni ankyrin 23/unc44 0.0032 0.0023 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Toxoplasma gondii cytochrome p450 superfamily protein 0.0024 0.0007 0.004
Onchocerca volvulus 0.0023 0.0005 0.0017
Echinococcus multilocularis synaptotagmin 15 0.0093 0.0144 0.0141
Echinococcus granulosus zinc finger protein 0.0025 0.0009 0.0009
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0754 0.1443 0.144
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.029 0.1996
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.0148 0.0246
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0029 0.0018 0.0059
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0082 0.0562
Brugia malayi Calcitonin receptor-like protein seb-1 0.0301 0.0552 0.092
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0087 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0075 0.0514
Brugia malayi Na,K-ATPase alpha subunit 0.0025 0.0009 0.0015
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0093 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0654 0.1245 0.2154
Echinococcus granulosus copine 9 0.0093 0.0144 0.0144
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0027 0.0013 0.0067
Loa Loa (eye worm) hypothetical protein 0.0027 0.0014 0.0024
Mycobacterium tuberculosis Probable dehydrogenase 0.0322 0.0593 0.8936
Entamoeba histolytica hypothetical protein 0.0093 0.0144 0.0812
Trichomonas vaginalis set domain proteins, putative 0.0477 0.0898 0.6184
Echinococcus granulosus TGF beta signal transducer SmadC 0.0032 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0032 0.0023 0.004
Brugia malayi tailless protein 0.0023 0.0005 0.0008
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0022 0.0126
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0023 0.0005 0.0077
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0031 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0095 0.0148 0.0256
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0754 0.1443 0.2496
Brugia malayi Synaptotagmin protein 3 0.0093 0.0144 0.024
Echinococcus multilocularis G protein coupled receptor 139 0.0168 0.0291 0.0287
Echinococcus multilocularis myotubularin protein 13 0.0552 0.1045 0.1042
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0048 0.0055 0.0052
Echinococcus multilocularis microtubule associated protein 2 0.511 1 1
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0024 0.0007 0.0102
Trypanosoma cruzi p450 reductase, putative 0.0027 0.0013 0.0411
Echinococcus multilocularis NEDD4 E3 ubiquitin protein ligase WWP1 0.0093 0.0144 0.0141
Echinococcus granulosus cpg binding protein 0.0097 0.0152 0.0151
Loa Loa (eye worm) hypothetical protein 0.0026 0.0013 0.0022
Entamoeba histolytica C2 domain containing protein 0.0093 0.0144 0.0812
Schistosoma mansoni synaptic ras gtpase activating protein syngap 0.0093 0.0144 0.0143
Trichomonas vaginalis C-MYB, putative 0.0047 0.0052 0.0355
Loa Loa (eye worm) AGC/NDR protein kinase 0.0754 0.1443 0.2496
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Schistosoma mansoni hypothetical protein 0.0032 0.0023 0.0022
Schistosoma mansoni single-minded 0.0048 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0112 0.0182 0.0314
Brugia malayi mbt repeat family protein 0.0054 0.0068 0.0113
Echinococcus granulosus synaptotagmin 2 0.0093 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0041 0.0278
Trichomonas vaginalis sucrase-isomaltase, putative 0.0078 0.0114 0.0778
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.0243 0.0405
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0032 0.0023 0.004
Onchocerca volvulus 0.01 0.0157 0.0529
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0005 0.0031
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0256 0.0463 0.0771
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0048 0.0055 0.0055
Toxoplasma gondii Sma protein 0.0093 0.0144 0.0991
Brugia malayi cytochrome P450 0.0024 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0032 0.0024 0.002
Brugia malayi MAP kinase sur-1 0.0117 0.0191 0.0317
Echinococcus multilocularis synaptotagmin 0.0093 0.0144 0.0141
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0031 0.0023 0.0037
Echinococcus granulosus expressed conserved protein 0.009 0.0137 0.0136
Schistosoma mansoni hypothetical protein 0.0093 0.0144 0.0143
Brugia malayi MH2 domain containing protein 0.0032 0.0024 0.0039
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0098 0.0153 0.0859
Echinococcus granulosus sodium channel protein 0.0152 0.0259 0.0259
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0024 0.0007 0.0138
Brugia malayi Animal haem peroxidase family protein 0.0052 0.0064 0.0105
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0027 0.0013 0.0013
Echinococcus granulosus serine:threonine protein kinase N2 0.0754 0.1443 0.1443
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0005 0.0031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0046 0.0307
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0002
Loa Loa (eye worm) heterochromatin protein 1 0.008 0.0119 0.0205
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0339 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Plasmodium vivax double C2-like domain-containing protein, putative 0.0093 0.0144 0.5998
Loa Loa (eye worm) copine family protein 0.0093 0.0144 0.0249
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0565 0.1071 0.1853
Echinococcus granulosus Ankyrin 0.0032 0.0023 0.0023
Leishmania major protein kinase, putative 0.003 0.002 0.0531
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0009 0.0008
Echinococcus granulosus intermediate filament protein 0.0027 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0088 0.0134 0.0232
Mycobacterium tuberculosis Probable oxidoreductase 0.0358 0.0663 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.005 0.0059 0.0199
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0022 0.0036
Loa Loa (eye worm) hypothetical protein 0.005 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0032 0.0023 0.004
Trypanosoma brucei C2 domain containing protein, putative 0.0093 0.0144 0.0971
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.003 0.0019 0.0016
Schistosoma mansoni cpg binding protein 0.009 0.0138 0.0137
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Brugia malayi Protein cec-1. 0.0023 0.0005 0.0008
Loa Loa (eye worm) ACC-1 protein 0.0031 0.0023 0.0039
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0024 0.0007 0.0138
Brugia malayi hypothetical protein 0.0163 0.0281 0.0467
Schistosoma mansoni intermediate filament proteins 0.0027 0.0014 0.0013
Schistosoma mansoni hypothetical protein 0.0093 0.0144 0.0143
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0022 0.0018
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0025 0.0009 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0046 0.0307
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0024 0.0007 0.0102
Echinococcus granulosus survival motor neuron protein 1 0.0489 0.0921 0.092
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0082 0.0122 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0029 0.0193
Loa Loa (eye worm) hypothetical protein 0.0048 0.0055 0.0096
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0048 0.0055 0.0055
Plasmodium falciparum ferlin, putative 0.0093 0.0144 0.5998
Echinococcus multilocularis transcription factor btf3 0.0035 0.0029 0.0025
Brugia malayi Animal haem peroxidase family protein 0.0052 0.0064 0.0105
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0031 0.0023 0.0037
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0355 0.0354
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Brugia malayi photoreceptor-specific nuclear receptor 0.0048 0.0055 0.0092
Schistosoma mansoni Smad4 0.0032 0.0024 0.0023
Echinococcus granulosus nuclear factor of activated T cells 5 0.0308 0.0567 0.0566
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0093 0.0144 0.0141
Loa Loa (eye worm) hypothetical protein 0.007 0.0098 0.017
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0351 0.065 0.1125
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0024 0.0042
Leishmania major hypothetical protein, conserved 0.0093 0.0144 0.4482
Plasmodium falciparum double C2-like domain-containing protein 0.0093 0.0144 0.5998
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0098 0.0153 0.0152
Entamoeba histolytica hypothetical protein 0.0093 0.0144 0.0812
Schistosoma mansoni thyroid hormone receptor 0.0048 0.0055 0.0054
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0049 0.0057 0.1699
Brugia malayi Copine family protein 0.0093 0.0144 0.024
Schistosoma mansoni synaptotagmin 0.0093 0.0144 0.0143
Leishmania major protein kinase, putative 0.003 0.002 0.0531
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0009 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Loa Loa (eye worm) animal heme peroxidase 0.0052 0.0064 0.011
Loa Loa (eye worm) C2 domain-containing protein 0.0093 0.0144 0.0249
Entamoeba histolytica protein kinase, putative 0.0111 0.0179 0.1007
Brugia malayi TAR-binding protein 0.0201 0.0355 0.0591
Echinococcus granulosus multiple C2 and transmembrane domain containing protein 0.0093 0.0144 0.0144
Schistosoma mansoni eyes absent homolog 0.0087 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0078 0.0114 0.0778
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0005 0.0031
Brugia malayi hypothetical protein 0.0023 0.0005 0.0008
Trypanosoma brucei C2 domain containing protein, putative 0.0093 0.0144 0.0971
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.055 0.1042 0.1041
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0049 0.0314
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.0005 0.0002
Schistosoma mansoni unc-13 (munc13) 0.0641 0.122 0.1219
Entamoeba histolytica hypothetical protein 0.0339 0.0626 0.3534
Brugia malayi diacylglycerol kinase 0.0548 0.1037 0.1727
Brugia malayi Glycosyl hydrolases family 31 protein 0.0078 0.0114 0.0189
Trypanosoma cruzi cysteine peptidase, putative 0.0075 0.0108 0.446
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0243 0.024
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0047 0.0053 0.0358
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Leishmania major glycosyl hydrolase-like protein 0.0029 0.0018 0.0455
Trichomonas vaginalis copine, putative 0.0093 0.0144 0.0987
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0055 0.0055
Onchocerca volvulus 0.1523 0.2953 1
Trichomonas vaginalis cation-transporting ATPase, putative 0.0036 0.0032 0.0213
Echinococcus granulosus calcium activated potassium channel 0.0027 0.0015 0.0014
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0029 0.0018 0.0608
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0074 0.0074
Plasmodium vivax SET domain protein, putative 0.0062 0.0082 0.336
Giardia lamblia DINP protein human, muc B family 0.0062 0.0083 0.4133
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0082 0.0122 0.0121
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0049 0.0057 0.0056
Echinococcus granulosus Rac GTPase activating protein 1 0.0548 0.1037 0.1036
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0029 0.0193
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.029 0.1996
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0047 0.0052 0.0355
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0048 0.0055 0.0054
Brugia malayi glutathione reductase 0.0141 0.0238 0.0396
Onchocerca volvulus 0.009 0.0138 0.0465
Leishmania major cytochrome p450-like protein 0.0024 0.0007 0.0112
Brugia malayi C1-like domain containing protein 0.0688 0.1312 0.2186
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0023
Loa Loa (eye worm) hypothetical protein 0.0641 0.122 0.211
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0025 0.0041
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0565 0.1071 0.1068
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0005 0.0031
Brugia malayi hypoxia-induced factor 1 0.015 0.0256 0.0426
Schistosoma mansoni smad1 5 8 and 0.0032 0.0024 0.0023
Trichomonas vaginalis glutathione reductase, putative 0.0049 0.0057 0.0386
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0117 0.0191 0.596
Schistosoma mansoni jun-related protein 0.0133 0.0223 0.0222
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0754 0.1443 0.2496
Schistosoma mansoni hypothetical protein 0.1282 0.248 0.2479
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0055 0.0092
Loa Loa (eye worm) hypothetical protein 0.0048 0.0055 0.0096
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0024 0.0007 0.0138
Echinococcus multilocularis protein piccolo 0.0093 0.0144 0.0141
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0031 0.0023 0.0019
Trichomonas vaginalis chromobox protein, putative 0.0053 0.0065 0.0441
Schistosoma mansoni hypothetical protein 0.0039 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0056 0.007 0.0121
Loa Loa (eye worm) C2 domain-containing protein 0.0093 0.0144 0.0249
Loa Loa (eye worm) transcription factor SMAD2 0.047 0.0884 0.1529
Loa Loa (eye worm) raf kinase 0.0548 0.1037 0.1793
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0358 0.0663 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0103 0.0163 0.0282
Schistosoma mansoni fer-1-related 0.0093 0.0144 0.0143
Schistosoma mansoni serine/threonine protein kinase 0.3811 0.7447 0.7447
Onchocerca volvulus 0.0031 0.0023 0.0075
Brugia malayi excitatory GABA receptor EXP-1A 0.0031 0.0023 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0048 0.0055 0.0096
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Schistosoma mansoni nAChR subunit 0.0031 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0036 0.0032 0.0212
Leishmania major p450 reductase, putative 0.0027 0.0013 0.0307
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0047 0.0052 0.0355
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0057 0.1699
Plasmodium vivax ferlin, putative 0.0093 0.0144 0.5998
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0087 0.0087
Echinococcus granulosus single minded 2 0.0036 0.0031 0.0031
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0057 0.2274
Loa Loa (eye worm) animal heme peroxidase 0.0052 0.0064 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Schistosoma mansoni serine/threonine-protein kinase 0.0022 0.0004 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0759 0.1451 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0024 0.0007 0.0138
Echinococcus multilocularis C2 calcium lipid binding region, CaLB 0.0093 0.0144 0.0141
Schistosoma mansoni peptidase 0.0024 0.0008 0.0007
Trypanosoma brucei C2 domain containing protein, putative 0.0093 0.0144 0.0971
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.003 0.002 0.0711
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Echinococcus granulosus Chromobox protein 3 0.0023 0.0005 0.0005
Trichomonas vaginalis synaptotagmin 1, 3, C.elegans, putative 0.0093 0.0144 0.0987
Trichomonas vaginalis synaptotagmin 1,2, putative 0.0093 0.0144 0.0987
Loa Loa (eye worm) hypothetical protein 0.0101 0.0159 0.0276
Brugia malayi Synapse defective protein 1 0.0093 0.0144 0.024
Schistosoma mansoni diacylglycerol kinase theta 0.0548 0.1037 0.1036
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0024 0.0007 0.0102
Brugia malayi MH2 domain containing protein 0.047 0.0884 0.1473
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0042 0.0038
Toxoplasma gondii endonuclease IV APN 0.0076 0.0111 0.0761
Schistosoma mansoni hypothetical protein 0.0095 0.0148 0.0147
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Trichomonas vaginalis copine, putative 0.0093 0.0144 0.0987
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0047 0.0052 0.0294
Trichomonas vaginalis PIKK family atypical protein kinase 0.0098 0.0153 0.1046
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0048 0.0055 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0075 0.0514
Loa Loa (eye worm) Smad1 0.0032 0.0024 0.0041
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0023 0.0005 0.0028
Onchocerca volvulus 0.0203 0.036 0.1217
Toxoplasma gondii diacylglycerol kinase, putative 0.0548 0.1037 0.7182
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0005 0.0028
Echinococcus granulosus serine:threonine protein kinase N2 0.0917 0.1763 0.1763
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0056 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0064 0.0438
Leishmania major calcium-translocating P-type ATPase 0.0036 0.0032 0.0902
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0108 0.0722
Brugia malayi Synapse defective protein 1 0.0093 0.0144 0.024
Trypanosoma brucei predicted C2 domain protein 0.0093 0.0144 0.0971
Trichomonas vaginalis AGC family protein kinase 0.0759 0.1451 1
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0024 0.0007 0.0102
Onchocerca volvulus Protein ultraspiracle homolog 0.0048 0.0055 0.0186
Schistosoma mansoni rho gtpase activating protein 0.0093 0.0144 0.0143
Schistosoma mansoni lamin 0.0027 0.0014 0.0013
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0005 0.0077
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0082 0.0079
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.01 0.0157 0.026
Loa Loa (eye worm) MH2 domain-containing protein 0.0032 0.0024 0.0041
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0056 0.007 0.0066
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0024 0.0488
Toxoplasma gondii NADPH-glutathione reductase 0.0049 0.0057 0.0386
Onchocerca volvulus 0.0442 0.0828 0.2805
Entamoeba histolytica C2 domain containing protein 0.0093 0.0144 0.0812
Onchocerca volvulus Putative cc2d1b protein 0.0093 0.0144 0.0487
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0114 0.4705
Loa Loa (eye worm) hypothetical protein 0.0241 0.0434 0.0751
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0103 0.0163 0.1124
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0062 0.0083 0.2532
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0024 0.0007 0.0102
Trypanosoma brucei protein kinase, putative 0.0117 0.0191 0.1291
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0049 0.0057 0.0853
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0031 0.0023 0.0019
Echinococcus granulosus synaptotagmin 0.0093 0.0144 0.0144
Onchocerca volvulus 0.0027 0.0014 0.0045
Onchocerca volvulus 0.0054 0.0068 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0005 0.0031
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0025 0.0009 0.0119
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0181 0.0317 0.0314
Echinococcus multilocularis protein kinase c eta type 0.0548 0.1037 0.1034
Toxoplasma gondii ferlin family protein 0.0093 0.0144 0.0991
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0022 0.0021
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0062 0.0083 0.1246
Onchocerca volvulus Netrin receptor homolog 0.0032 0.0023 0.0076
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Brugia malayi phospholipase C homolog 0.0093 0.0144 0.024
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0031 0.0052
Loa Loa (eye worm) hypothetical protein 0.01 0.0157 0.0272
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Leishmania major cathepsin L-like protease 0.0075 0.0108 0.3333
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0024 0.0007 0.0138
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0031 0.0023 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Echinococcus granulosus jun protein 0.0164 0.0283 0.0282
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0108 0.0722
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0463 0.3187
Brugia malayi Uncoordinated protein 44 0.0032 0.0023 0.0037
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0024 0.0007 0.0102
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0049 0.0057 0.2274
Schistosoma mansoni terminal deoxycytidyl transferase 0.0056 0.007 0.0069
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0025 0.0009 0.004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0057 0.5
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0048 0.0055 0.0052
Echinococcus granulosus GPCR family 2 0.0095 0.0148 0.0148
Loa Loa (eye worm) RhoGAP domain-containing protein 0.055 0.1042 0.1802
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0025 0.0009 0.0185
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0033 0.0025 0.0149
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Entamoeba histolytica hypothetical protein 0.0023 0.0005 0.0028
Echinococcus granulosus calpain 5 0.0093 0.0144 0.0144
Trypanosoma cruzi DNA polymerase kappa, putative 0.0082 0.0122 0.506
Echinococcus multilocularis neutral alpha glucosidase AB 0.0078 0.0114 0.011
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0048 0.0055 0.0055
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0025 0.0921
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0036 0.0032 0.0028
Brugia malayi Cytochrome P450 family protein 0.0032 0.0024 0.004
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0181 0.0317 0.0317
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0023 0.0037
Echinococcus multilocularis active breakpoint cluster region 0.0093 0.0144 0.0141
Giardia lamblia NADH oxidase lateral transfer candidate 0.0049 0.0057 0.2708
Entamoeba histolytica protein kinase, putative 0.0022 0.0004 0.0018
Trypanosoma brucei DNA polymerase IV, putative 0.0082 0.0122 0.0819
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0024 0.0143
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.0122 0.0819
Echinococcus granulosus netrin receptor unc 5 0.0032 0.0023 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0463 0.3187
Trypanosoma brucei unspecified product 0.0038 0.0036 0.0225
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0098 0.0153 0.0859
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0023 0.0037
Entamoeba histolytica Rap/Ran GTPase activating protein, putative 0.0093 0.0144 0.0812
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0463 0.3187
Schistosoma mansoni nAChR subunit 0.0031 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Echinococcus multilocularis protein patched 0.0041 0.0041 0.0038
Schistosoma mansoni synaptotagmin 12 0.0093 0.0144 0.0143
Schistosoma mansoni alpha-glucosidase 0.0302 0.0554 0.0553
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0082 0.0081
Trichomonas vaginalis vab10 spectraplakin, putative 0.0093 0.0144 0.0987
Echinococcus granulosus raf serine:threonine protein kinase 0.0548 0.1037 0.1036
Schistosoma mansoni hypothetical protein 0.0093 0.0144 0.0143
Echinococcus granulosus mitogen activated protein kinase 0.0117 0.0191 0.019
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0014 0.0024
Schistosoma mansoni hypothetical protein 0.0095 0.0148 0.0147
Loa Loa (eye worm) hypothetical protein 0.1523 0.2953 0.5107
Brugia malayi hypothetical protein 0.0339 0.0626 0.1043
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0024 0.0007 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0108 0.0722
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0009 0.0009
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0078 0.0114 0.3506
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0031 0.0023 0.0037
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0078 0.0114 0.0781
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0022 0.0018
Echinococcus granulosus dna polymerase kappa 0.0082 0.0122 0.0122
Echinococcus multilocularis calcium activated potassium channel 0.0027 0.0015 0.0011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0057 0.2274
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0036 0.0032 0.1208
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0031 0.0023 0.0022
Onchocerca volvulus 0.0123 0.0202 0.0682
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0027 0.0013 0.0307
Echinococcus multilocularis smad 0.0032 0.0024 0.002
Schistosoma mansoni chromobox protein 0.008 0.0119 0.0118
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0048 0.0055 0.0054
Schistosoma mansoni nAChR subunit 0.0031 0.0023 0.0022
Echinococcus granulosus synaptotagmin 0.0093 0.0144 0.0144
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0033 0.0025 0.0688
Brugia malayi Copine VIII 0.0093 0.0144 0.024
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0024 0.0042
Echinococcus multilocularis copine 9 0.0093 0.0144 0.0141
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0181 0.0317 1
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0031 0.0023 0.0022
Schistosoma mansoni alpha-glucosidase 0.0302 0.0554 0.0553
Trypanosoma brucei PAB1-binding protein , putative 0.01 0.0157 0.106
Trypanosoma brucei unspecified product 0.0076 0.0109 0.073
Schistosoma mansoni E3 ubiquitin-protein ligase nedd-4 0.0093 0.0144 0.0143
Brugia malayi ecdysteroid receptor 0.0048 0.0055 0.0092
Brugia malayi hypothetical protein 0.0146 0.0248 0.0413
Schistosoma mansoni hypothetical protein 0.0854 0.1639 0.1638
Trichomonas vaginalis Circumsporozoite protein precursor, putative 0.0093 0.0144 0.0987
Schistosoma mansoni serine/threonine protein kinase 0.3811 0.7447 0.7447
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0022 0.0018
Trichomonas vaginalis synaptotagmin, putative 0.0093 0.0144 0.0987
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0048 0.0055 0.0052
Trichomonas vaginalis CMGC family protein kinase 0.0117 0.0191 0.1307
Trichomonas vaginalis AGC family protein kinase 0.0759 0.1451 1
Echinococcus granulosus nuclear receptor nhr 48 0.0023 0.0005 0.0005
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0036 0.0032 0.1208
Echinococcus granulosus neuropeptide receptor 0.0168 0.0291 0.029
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0049 0.0057 0.0368
Entamoeba histolytica hypothetical protein 0.0093 0.0144 0.0812
Schistosoma mansoni glut4 vesicle protein-related 0.0093 0.0144 0.0143
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0024 0.0007 0.0138
Loa Loa (eye worm) C2 domain-containing protein 0.0093 0.0144 0.0249
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0093 0.0144 0.0144
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0114 0.0778
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0059 0.0401
Trypanosoma brucei rac serine-threonine kinase, putative 0.0759 0.1451 1
Brugia malayi Cation transporter family protein 0.0031 0.0023 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0308 0.2119
Mycobacterium ulcerans endonuclease IV 0.0076 0.0111 0.2257
Onchocerca volvulus Peroxidasin homolog 0.0052 0.0064 0.0214
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0042 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0104 0.0707
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0055
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.0018 0.0099
Schistosoma mansoni myelin transcription factor 1 myt1 0.0062 0.0083 0.0082
Loa Loa (eye worm) glutaminase 2 0.027 0.0491 0.0848
Echinococcus multilocularis geminin 0.0854 0.1639 0.1636
Trypanosoma cruzi target of rapamycin kinase 3 0.0078 0.0114 0.4692
Trichomonas vaginalis AGC family protein kinase 0.0754 0.1443 0.9944
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0064 0.0438
Echinococcus granulosus death domain containing protein 0.0032 0.0023 0.0022
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0098 0.0153 0.0149
Schistosoma mansoni steroid hormone receptor ad4bp 0.0048 0.0055 0.0054
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0243 0.0242
Brugia malayi Pre-SET motif family protein 0.0419 0.0785 0.1307
Leishmania major c2 domain protein, putative 0.0093 0.0144 0.4482
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0243 0.024
Onchocerca volvulus 0.0027 0.0014 0.0045
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0031 0.0023 0.0037
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0043 0.0046 0.0307
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0024 0.0007 0.0112
Entamoeba histolytica diacylglycerol kinase, putative 0.0548 0.1037 0.5852
Echinococcus granulosus protein kinase C gamma type 0.3263 0.6371 0.6371
Schistosoma mansoni synaptotagmin-like protein 0.0093 0.0144 0.0143
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0025 0.0011 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0032 0.0023 0.0019
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0022 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0104 0.0707
Trypanosoma cruzi cysteine peptidase, putative 0.0075 0.0108 0.446
Entamoeba histolytica PH domain containing protein kinase, putative 0.0022 0.0004 0.0018
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0049 0.0057 0.0094
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0049 0.0057 0.2274
Brugia malayi Latrophilin receptor protein 2 0.0095 0.0148 0.0246
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0023 0.0038
Entamoeba histolytica protein kinase, putative 0.0022 0.0004 0.0018
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0054 0.0068 0.0229
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0055 0.0092
Loa Loa (eye worm) nuclear receptor NHR-67 0.0023 0.0005 0.0009
Echinococcus granulosus muscleblind protein 0.0654 0.1245 0.1245
Schistosoma mansoni nAChR subunit 0.0031 0.0023 0.0022
Brugia malayi Ras association domain family 1 isoform A 0.0548 0.1037 0.1727
Echinococcus multilocularis dna polymerase eta 0.0056 0.007 0.0066
Trypanosoma brucei DNA polymerase eta, putative 0.0056 0.007 0.0459
Echinococcus multilocularis zinc finger protein 0.0025 0.0009 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0064 0.0438
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Brugia malayi conserved hypotetical protein 0.0023 0.0005 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0055 0.0054
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0057 0.2274
Brugia malayi chromobox protein homolog 3 0.005 0.0059 0.0098
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0005 0.0004
Echinococcus granulosus multiple C2 and transmembrane domain containing protein 0.0093 0.0144 0.0144
Trypanosoma brucei glucosidase, putative 0.0078 0.0114 0.0762
Leishmania major DNA polymerase kappa, putative 0.0062 0.0083 0.2532
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0114 0.0778
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0041 0.0038
Loa Loa (eye worm) hypothetical protein 0.0301 0.0552 0.0955
Brugia malayi Protein kinase domain containing protein 0.0754 0.1443 0.2405
Trichomonas vaginalis MYB3r3, putative 0.0047 0.0052 0.0355
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0031 0.0023 0.0037
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0023 0.0005 0.0002
Schistosoma mansoni smad1 5 8 and 0.0032 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0055 0.0096
Entamoeba histolytica hypothetical protein 0.0023 0.0005 0.0028
Loa Loa (eye worm) hypothetical protein 0.0054 0.0068 0.0117
Loa Loa (eye worm) hypothetical protein 0.0112 0.0181 0.0314
Leishmania major copine i-like protein 0.0093 0.0144 0.4482
Loa Loa (eye worm) hypothetical protein 0.0146 0.0248 0.043
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0137 0.0136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0108 0.0722
Brugia malayi hypothetical protein 0.0241 0.0434 0.0723
Echinococcus granulosus glycine receptor subunit alpha 1 0.0031 0.0023 0.0022
Loa Loa (eye worm) mbt repeat family protein 0.0054 0.0068 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0113 0.0775
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.0018 0.0117
Echinococcus granulosus ecdysone induced protein 78C 0.0048 0.0055 0.0055
Brugia malayi calpain 5 0.0093 0.0144 0.024
Entamoeba histolytica hypothetical protein 0.0339 0.0626 0.3534
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0358 0.0663 1
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0054 0.0068 0.0067
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0098 0.0153 0.636
Trypanosoma brucei DNA polymerase IV, putative 0.0076 0.0109 0.073
Schistosoma mansoni chromobox protein 0.0023 0.0005 0.0004
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0082 0.0122 0.0118
Loa Loa (eye worm) hypothetical protein 0.0041 0.0042 0.0072
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0229 0.0228
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0463 0.3187
Echinococcus multilocularis calcium transporting atpase 0.0025 0.0009 0.0005
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0022 0.0781
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0012 0.0078
Onchocerca volvulus 0.0129 0.0214 0.0723
Echinococcus multilocularis sodium channel protein 0.0152 0.0259 0.0255
Brugia malayi CXXC zinc finger family protein 0.009 0.0138 0.0229
Echinococcus granulosus otoferlin 0.0093 0.0144 0.0144
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0027 0.0013 0.0067
Plasmodium vivax heterochromatin protein 1, putative 0.0023 0.0005 0.0077
Schistosoma mansoni cytochrome P450 0.0024 0.0007 0.0006
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0025 0.0009 0.0059
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0022 0.0781
Leishmania major hypothetical protein, conserved 0.0093 0.0144 0.4482
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0036 0.0032 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0025 0.0167
Echinococcus multilocularis peroxidasin 0.0052 0.0064 0.006
Loa Loa (eye worm) phosphatidylinositol 3 0.0098 0.0153 0.0264
Treponema pallidum NADH oxidase 0.0049 0.0057 0.5
Echinococcus multilocularis N chimaerin 0.055 0.1042 0.1038
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0059 0.0401
Schistosoma mansoni unc-13 (munc13) 0.0645 0.1227 0.1227
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0023 0.0037
Echinococcus granulosus extended synaptotagmin 2 0.0093 0.0144 0.0144
Entamoeba histolytica C2 domain containing protein 0.0093 0.0144 0.0812
Trypanosoma cruzi synaptotagmin, putative 0.0093 0.0144 0.5998
Brugia malayi steroid hormone receptor 0.0048 0.0055 0.0092
Onchocerca volvulus 0.0477 0.0898 0.3041
Trichomonas vaginalis pc-MYB2, putative 0.0047 0.0052 0.0355
Onchocerca volvulus 0.0093 0.0144 0.0487
Onchocerca volvulus 0.0641 0.122 0.4131
Leishmania major hypothetical protein, conserved 0.01 0.0157 0.4895
Echinococcus granulosus tar DNA binding protein 0.0201 0.0355 0.0355
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0029 0.005
Toxoplasma gondii aldehyde dehydrogenase 0.0181 0.0317 0.2191
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Schistosoma mansoni glutaminase 0.027 0.0491 0.049
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0062 0.0083 0.0082
Onchocerca volvulus 0.0112 0.0181 0.0613
Trichomonas vaginalis MYB72, putative 0.0047 0.0052 0.0355
Echinococcus multilocularis musashi 0.0027 0.0014 0.001
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0025 0.0009 0.004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0005 0.0031
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0005 0.0028
Trichomonas vaginalis cation-transporting ATPase, putative 0.0025 0.0009 0.0059
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.003 0.0019 0.0019
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0093 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0641 0.122 0.122
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0024 0.0007 0.0138
Loa Loa (eye worm) hypothetical protein 0.0241 0.0434 0.0751
Trichomonas vaginalis splicing factor 3A subunit, putative 0.0093 0.0144 0.0987
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0079 0.0116 0.0114
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0014 0.0024
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Trypanosoma cruzi cytoskeleton associated protein, putative 0.0093 0.0144 0.5998
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0148 0.0148
Echinococcus multilocularis chromobox protein 1 0.008 0.0119 0.0115
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0031 0.0027
Echinococcus multilocularis neuropeptide s receptor 0.1448 0.2806 0.2804
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.0122 0.0819
Schistosoma mansoni netrin receptor unc5 0.0032 0.0023 0.0022
Brugia malayi protein kinase C3,putative 0.0565 0.1071 0.1785
Loa Loa (eye worm) glutathione reductase 0.0141 0.0238 0.0412
Schistosoma mansoni hypothetical protein 0.0206 0.0365 0.0364
Brugia malayi flavodoxin family protein 0.0027 0.0013 0.0021
Entamoeba histolytica protein kinase, putative 0.0022 0.0004 0.0018
Schistosoma mansoni ATPase 0.0036 0.0032 0.0031
Brugia malayi bZIP transcription factor family protein 0.0164 0.0283 0.0471
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0358 0.0663 1
Onchocerca volvulus 0.0093 0.0144 0.0487
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0095
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0015 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0082 0.0122 0.506
Loa Loa (eye worm) hypothetical protein 0.0087 0.0132 0.0229
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0049 0.0048
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0029 0.1079
Loa Loa (eye worm) synaptotagmin-1 0.0093 0.0144 0.0249
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0022 0.0004 0.0018
Loa Loa (eye worm) hypothetical protein 0.2071 0.4028 0.6967
Leishmania major cytochrome p450-like protein 0.0032 0.0024 0.0659
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Plasmodium falciparum thioredoxin reductase 0.0049 0.0057 0.2274
Echinococcus multilocularis neural cell expressed, developmentally 0.0093 0.0144 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0024 0.0007 0.0102
Brugia malayi nuclear receptor NHR-88 0.0023 0.0005 0.0008
Plasmodium falciparum ferlin, putative 0.0093 0.0144 0.5998
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Brugia malayi nuclear receptor RXR 0.0025 0.0011 0.0017
Trypanosoma brucei DNA polymerase IV, putative 0.0082 0.0122 0.0819
Trichomonas vaginalis Proline-rich protein, putative 0.0093 0.0144 0.0987
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0057 0.1699
Schistosoma mansoni hypothetical protein 0.0041 0.0042 0.0041
Entamoeba histolytica PH domain containing protein kinase, putative 0.0022 0.0004 0.0018
Loa Loa (eye worm) hypothetical protein 0.0087 0.0132 0.0229
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0078 0.0114 0.0641
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0025 0.0167
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0754 0.1443 0.2496
Schistosoma mansoni DNA polymerase eta 0.0056 0.007 0.0069
Loa Loa (eye worm) AGC/PKN protein kinase 0.0754 0.1443 0.2496
Mycobacterium ulcerans aldehyde dehydrogenase 0.0181 0.0317 0.6463
Loa Loa (eye worm) FAD binding domain-containing protein 0.0027 0.0013 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0108 0.0722
Mycobacterium tuberculosis Conserved hypothetical protein 0.0056 0.007 0.1052
Trypanosoma cruzi cruzipain precursor, putative 0.0075 0.0108 0.446
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0025 0.0009 0.0059
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0022 0.0781
Schistosoma mansoni unc-13 (munc13) 0.0093 0.0144 0.0143
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0024 0.0007 0.0138
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.5019 0.9821 0.9821
Loa Loa (eye worm) thioredoxin reductase 0.0141 0.0238 0.0412
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0064 0.0438
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.0122 0.0819
Trypanosoma cruzi hypothetical protein, conserved 0.0093 0.0144 0.5998
Schistosoma mansoni protein kinase C mu 0.0688 0.1312 0.1311
Plasmodium falciparum ataxin-2 like protein, putative 0.01 0.0157 0.6551
Entamoeba histolytica hypothetical protein, conserved 0.0093 0.0144 0.0812
Schistosoma mansoni hypothetical protein 0.01 0.0157 0.0156
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Schistosoma mansoni hypothetical protein 0.0093 0.0144 0.0143
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0057 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0005 0.0031
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0023 0.0005 0.0004
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0049 0.0045
Loa Loa (eye worm) steroid hormone receptor 0.0048 0.0055 0.0096
Entamoeba histolytica deoxycytidyl transferase, putative 0.0056 0.007 0.0393
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0151 0.015
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0047 0.0052 0.0294
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0025 0.0011 0.001
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0103 0.0163 0.0162
Brugia malayi Smad1 0.0032 0.0024 0.0039
Loa Loa (eye worm) hypothetical protein 0.0674 0.1286 0.2223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0104 0.0707
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0027 0.0013 0.0411
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.002 0.0016
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0025 0.0009 0.0057
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0025 0.0009 0.0059
Echinococcus granulosus chromobox protein 1 0.008 0.0119 0.0118
Loa Loa (eye worm) hypothetical protein 0.0047 0.0054 0.0093
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0056 0.0055
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.0148 0.0256
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0011 0.001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0046 0.0307
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0098 0.0153 0.4752
Entamoeba histolytica C2 domain containing protein 0.0093 0.0144 0.0812
Echinococcus granulosus myotubularin protein 13 0.0552 0.1045 0.1044
Trichomonas vaginalis cation-transporting ATPase, putative 0.0036 0.0032 0.0213
Brugia malayi PAS domain containing protein 0.0048 0.0056 0.0093
Brugia malayi hypothetical protein 0.0064 0.0088 0.0145
Schistosoma mansoni serine/threonine protein kinase 0.0754 0.1443 0.1442
Brugia malayi ecdysone receptor 0.0023 0.0005 0.0008
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0025 0.0009 0.0051
Brugia malayi mbt repeat family protein 0.0054 0.0068 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0005 0.0031
Onchocerca volvulus Chorion peroxidase homolog 0.0052 0.0064 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0085 0.0582
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0022 0.0004 0.0016
Schistosoma mansoni rabphilin-3a 0.0093 0.0144 0.0143
Plasmodium falciparum heterochromatin protein 1 0.0023 0.0005 0.0077
Brugia malayi orphan nuclear receptor NR2E1 0.0023 0.0005 0.0008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0048 0.0055 0.0054
Schistosoma mansoni hypothetical protein 0.0339 0.0626 0.0625
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0754 0.1443 0.144
Onchocerca volvulus 0.0036 0.0031 0.0105
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0025 0.0009 0.0016
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0029 0.0161
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0098 0.0153 0.0152
Onchocerca volvulus 0.0093 0.0144 0.0487
Brugia malayi glutaminase DH11.1 0.027 0.0491 0.0817
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0688 0.1312 0.2269
Loa Loa (eye worm) hypothetical protein 0.0159 0.0274 0.0474
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.0005 0.0017
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0027 0.0013 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0049 0.0314
Loa Loa (eye worm) hypothetical protein 0.0548 0.1037 0.1793
Echinococcus granulosus protein kinase c eta type 0.0548 0.1037 0.1036
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Echinococcus granulosus mothers against decapentaplegic 5 0.0032 0.0024 0.0023
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0023 0.0005 0.0005
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0049 0.0057 0.1699
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0031 0.0023 0.0019
Echinococcus multilocularis Protein kinase C, brain isozyme 0.3811 0.7447 0.7446
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.0148 0.0148
Giardia lamblia Myb 1-like protein 0.0047 0.0053 0.2488
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0031 0.0023 0.0019
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0043 0.0046 0.0307
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0082 0.0122 0.0836
Brugia malayi nuclear hormone receptor family member odr-7 0.0023 0.0005 0.0008
Trichomonas vaginalis maltase-glucoamylase, putative 0.0029 0.0018 0.0117
Loa Loa (eye worm) hypothetical protein 0.0095 0.0148 0.0256
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0098 0.0153 0.0254
Echinococcus multilocularis tumor protein p63 0.0691 0.1317 0.1314
Trypanosoma cruzi DNA polymerase eta, putative 0.0056 0.007 0.2837
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0322 0.0593 0.8936
Brugia malayi Blistered cuticle protein 3 0.0052 0.0064 0.0105
Trichomonas vaginalis maltase-glucoamylase, putative 0.0078 0.0114 0.0778
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0011 0.0017
Onchocerca volvulus 0.067 0.1277 0.4326
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0022 0.0038
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0031 0.0023 0.0037
Loa Loa (eye worm) LGC-31 protein 0.0031 0.0023 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0093 0.0144 0.5998
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0047 0.0299
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.003 0.002 0.0711
Brugia malayi nuclear hormone receptor family member nhr-6 0.0023 0.0005 0.0008
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0322 0.0593 0.8936
Echinococcus multilocularis dna polymerase kappa 0.0082 0.0122 0.0119
Brugia malayi Protein kinase domain containing protein 0.0759 0.1451 0.2418
Loa Loa (eye worm) RNA binding protein 0.0201 0.0355 0.0614
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0093 0.0144 0.0144
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0301 0.0552 0.092
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0056 0.007 0.0069
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0024 0.0007 0.0138
Mycobacterium leprae putative cytochrome p450 0.0024 0.0007 0.0102
Echinococcus granulosus histone acetyltransferase MYST2 0.0062 0.0083 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0144 0.0987
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0055 0.0092
Brugia malayi Bromodomain containing protein 0.0079 0.0117 0.0194
Loa Loa (eye worm) hypothetical protein 0.1523 0.2953 0.5107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0064 0.0436
Echinococcus multilocularis nAChR subunit 0.0031 0.0023 0.0019
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0031 0.0023 0.0022
Entamoeba histolytica protein kinase, putative 0.0754 0.1443 0.8146
Entamoeba histolytica hypothetical protein 0.0022 0.0004 0.0018
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0548 0.1037 0.1793
Brugia malayi Peroxidasin 0.0052 0.0064 0.0105
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0024 0.0008 0.0044
Brugia malayi STAT protein, DNA binding domain containing protein 0.0131 0.0219 0.0364
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0754 0.1443 0.2496
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0025 0.0009 0.0008
Echinococcus multilocularis protein dispatched 1 0.0047 0.0053 0.0049
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0018 0.0117
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0057 0.0368
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0191 0.0189
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Leishmania major hypothetical protein, conserved 0.0093 0.0144 0.4482
Loa Loa (eye worm) animal heme peroxidase 0.0052 0.0064 0.011
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0025 0.0009 0.0187
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Echinococcus multilocularis serine:threonine protein kinase N2 0.0754 0.1443 0.144
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0025 0.0009 0.0051
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0023 0.0037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0046 0.0307
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0039
Brugia malayi p70 ribosomal S6 kinase beta 0.0754 0.1443 0.2405
Loa Loa (eye worm) MBCTL1 0.0062 0.0083 0.0143
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.0005 0.0005
Leishmania major phospholipase c-like protein 0.0093 0.0144 0.4482
Trichomonas vaginalis PIKK family atypical protein kinase 0.0083 0.0125 0.0852
Loa Loa (eye worm) hypothetical protein 0.0103 0.0163 0.0282
Onchocerca volvulus Huntingtin homolog 0.0241 0.0434 0.1469
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0023 0.0005 0.0004
Schistosoma mansoni rac gtpase activating protein 0.0548 0.1037 0.1036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0055 0.0052
Brugia malayi Protein kinase domain containing protein 0.0565 0.1071 0.1785
Echinococcus multilocularis lysosomal alpha glucosidase 0.0351 0.065 0.0647
Brugia malayi MH2 domain containing protein 0.0032 0.0024 0.0039
Toxoplasma gondii Elicitor-responsive protein, putative 0.0093 0.0144 0.0991
Entamoeba histolytica hypothetical protein 0.0093 0.0144 0.0812
Brugia malayi C2 domain containing protein 0.0093 0.0144 0.024
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0055 0.0055
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0046 0.0307
Plasmodium falciparum thioredoxin reductase 0.0141 0.0238 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0082 0.0122 0.506
Brugia malayi Associated with TFs and helicases family protein 0.0023 0.0005 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0025 0.0167
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0442 0.0828 0.1433
Loa Loa (eye worm) cytochrome P450 family protein 0.0068 0.0094 0.0163
Echinococcus granulosus synaptotagmin 0.0093 0.0144 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0083 0.0548
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0031 0.0028
Echinococcus granulosus dnaJ subfamily B 0.1282 0.248 0.248
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0117 0.0191 0.0329
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0117 0.0191 0.7975
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0024 0.0007 0.0102
Schistosoma mansoni hypothetical protein 0.0039 0.0038 0.0037
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0243 0.0242
Plasmodium falciparum ataxin-2 like protein, putative 0.01 0.0157 0.6551
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0031
Brugia malayi Cation transporter family protein 0.0031 0.0023 0.0037
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0093 0.0144 0.0249
Echinococcus multilocularis serine:threonine protein kinase 38 0.0754 0.1443 0.144
Entamoeba histolytica protein kinase, putative 0.0022 0.0004 0.0018
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0093 0.0144 0.0141
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0005 0.0077
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0057 0.2274
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Trypanosoma brucei hypothetical protein, conserved 0.0093 0.0144 0.0971
Schistosoma mansoni hypothetical protein 0.0024 0.0007 0.0006
Plasmodium vivax thioredoxin reductase, putative 0.0141 0.0238 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0049 0.0057 0.0368
Plasmodium vivax ferlin, putative 0.0093 0.0144 0.5998
Giardia lamblia Kinase, CMGC MAPK 0.0117 0.0191 1
Echinococcus granulosus synaptotagmin 0.0093 0.0144 0.0144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0075 0.0514
Entamoeba histolytica protein kinase, putative 0.0022 0.0004 0.0018
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0007 0.015
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0355 0.0354
Trichomonas vaginalis ion channel nompc, putative 0.0093 0.0144 0.0987
Schistosoma mansoni peroxidasin 0.0052 0.0064 0.0063
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0117 0.0191 0.7975
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0025 0.0167
Onchocerca volvulus Dual oxidase homolog 0.0052 0.0064 0.0214
Entamoeba histolytica PH domain containing protein kinase, putative 0.0022 0.0004 0.0018
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.2526 0.4924 0.8516
Schistosoma mansoni nedd-4-like E3 ubiquitin-protein ligase 0.0093 0.0144 0.0143
Loa Loa (eye worm) hypothetical protein 0.0048 0.0055 0.0096
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0754 0.1443 0.1443
Leishmania major DNA polymerase eta, putative 0.0056 0.007 0.212
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0093 0.0144 0.5998
Schistosoma mansoni caspase-7 (C14 family) 0.0059 0.0076 0.0075
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0215 0.0383 0.0382
Onchocerca volvulus 0.0052 0.0064 0.0214
Entamoeba histolytica DENN domain protein 0.0093 0.0144 0.0812
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0024 0.0007 0.0138
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0023 0.0005 0.0002
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0005 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0024 0.0007 0.0102
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.2416 0.4706 0.4704
Echinococcus multilocularis Protein lozenge 0.0055 0.007 0.0066
Trichomonas vaginalis AGC family protein kinase 0.0022 0.0004 0.0018
Echinococcus granulosus NEDD4 E3 ubiquitin protein ligase WWP1 0.0093 0.0144 0.0144
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0024 0.0159
Echinococcus multilocularis histone acetyltransferase MYST2 0.0062 0.0083 0.0079
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0029 0.0175
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0048 0.0055 0.0054
Onchocerca volvulus 0.0101 0.0159 0.0539
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0024 0.0007 0.0138
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0047 0.0052 0.0355
Schistosoma mansoni nAChR subunit 0.0031 0.0023 0.0022
Brugia malayi hypothetical protein 0.0112 0.0182 0.0302
Leishmania major cytochrome p450-like protein 0.0024 0.0007 0.0112
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0024 0.0007 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0754 0.1443 0.1442
Trichomonas vaginalis MYB, putative 0.0047 0.0053 0.0358
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0053 0.0065 0.0219
Entamoeba histolytica hypothetical protein 0.0022 0.0004 0.0018
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0047 0.0052 0.0294
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0093 0.0144 0.014
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0025 0.0921
Chlamydia trachomatis endonuclease IV 0.0076 0.0111 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0062 0.0083 0.0079
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0148 0.0835
Echinococcus multilocularis synaptotagmin protein 4 0.0093 0.0144 0.0141
Trypanosoma brucei cAMP binding protein, putative 0.0093 0.0144 0.0971
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Echinococcus multilocularis Smad4 0.0032 0.0024 0.002
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Echinococcus multilocularis unc 13 (munc13) 0.0641 0.122 0.1217
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.003 0.002 0.0711
Trichomonas vaginalis Heterochromatin protein, putative 0.0023 0.0005 0.0031
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.0069
Schistosoma mansoni vav2 0.0554 0.105 0.1049
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0032 0.0023 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0759 0.1451 1
Trichomonas vaginalis synaptotagmin, putative 0.0093 0.0144 0.0987
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0027 0.0013 0.0411
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0048 0.0055 0.0092
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0049 0.0057 0.2274
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0064 0.0436
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0025 0.0009 0.025
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0082 0.0122 0.0202
Brugia malayi FAD binding domain containing protein 0.0027 0.0013 0.0021
Toxoplasma gondii hypothetical protein 0.0093 0.0144 0.0991
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0025 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0005 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0093 0.0144 0.5998
Onchocerca volvulus Cell death protein 3 homolog 0.0059 0.0076 0.0257
Schistosoma mansoni hypothetical protein 0.0331 0.0611 0.061
Echinococcus granulosus tumor protein p63 0.0691 0.1317 0.1317
Schistosoma mansoni ATPase 0.0036 0.0032 0.0031
Leishmania major cytochrome P450 reductase, putative 0.0024 0.0007 0.0117
Plasmodium falciparum glutathione reductase 0.0049 0.0057 0.2274
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0031 0.0023 0.0039
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0148 0.0246
Loa Loa (eye worm) helicase 0.0023 0.0005 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0055 0.0092
Brugia malayi Cytochrome P450 family protein 0.0024 0.0007 0.0011
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.01 0.0157 0.0156
Schistosoma mansoni otoferlin 0.0093 0.0144 0.0143
Trypanosoma brucei hypothetical protein, conserved 0.0093 0.0144 0.0971
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0047 0.0052 0.0294
Brugia malayi M-phase phosphoprotein, mpp8 0.0112 0.0181 0.0302
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0023 0.0005 0.0005
Trichomonas vaginalis synaptotagmin, putative 0.0093 0.0144 0.0987
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0117 0.0191 0.7975
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0029 0.1079
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0027 0.0013 0.001
Brugia malayi protein kinase C II. 0.2295 0.447 0.745
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0113 0.0775
Trichomonas vaginalis copine, putative 0.0093 0.0144 0.0987
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0018 0.0117
Echinococcus granulosus glycine receptor subunit alpha 1 0.0031 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0009
Schistosoma mansoni alpha glucosidase 0.0078 0.0114 0.0113
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0047 0.0052 0.0355
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0022 0.0143
Schistosoma mansoni serine/threonine protein kinase 0.0754 0.1443 0.1442
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0103 0.0163 0.0162
Entamoeba histolytica protein kinase, putative 0.0759 0.1451 0.8192
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0079 0.0116 0.0114
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0078 0.0114 0.0641
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0179
Echinococcus granulosus protein piccolo 0.0093 0.0144 0.0144
Trichomonas vaginalis synaptotagmin, putative 0.0093 0.0144 0.0987
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Schistosoma mansoni copine 0.0093 0.0144 0.0143
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0078 0.0114 0.0759
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0047 0.0299
Brugia malayi Heterochromatin protein 1 0.008 0.0119 0.0197
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0098 0.0153 0.4752
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0108 0.0722
Echinococcus granulosus myoferlin 0.0093 0.0144 0.0144
Plasmodium vivax ataxin-2 like protein, putative 0.01 0.0157 0.6551
Echinococcus multilocularis 0.0093 0.0144 0.0141
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0111 0.4584
Echinococcus granulosus lamin 0.0027 0.0014 0.0013
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.003 0.002 0.0711
Brugia malayi SET domain containing protein 0.0027 0.0014 0.0022
Schistosoma mansoni coup transcription factor 0.0048 0.0055 0.0054
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0024 0.0042
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0036 0.0031 0.0052
Mycobacterium ulcerans DNA polymerase IV 0.0082 0.0122 0.2485
Mycobacterium leprae Conserved hypothetical protein 0.0024 0.0007 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0048 0.0055 0.0096
Echinococcus multilocularis Ankyrin 0.0032 0.0023 0.0019
Loa Loa (eye worm) hypothetical protein 0.0093 0.0144 0.0249
Loa Loa (eye worm) hypothetical protein 0.2277 0.4435 0.767

Activities

Activity type Activity value Assay description Source Reference
Diuretic effect (functional) = 2 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (K+) at a time period of 0-5 hr for dose 9 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 3 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (K+) at a time period of 0-5 hr for dose 3 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 4 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (K+) at a time period of 0-5 hr for dose 27 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 7 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (K+) at a time period of 0-5 hr for dose 81 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 17 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Na+) at a time period of 0-5 hr for dose 3 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 28 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Cl-) at a time period of 0-5 hr for dose 3 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 39 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Cl-) at a time period of 0-5 hr for dose 9 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 49 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Cl-) at a time period of 0-5 hr for dose 27 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 79 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Na+) at a time period of 0-5 hr for dose 9 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 89 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (K+) at a time period of 0-24 hr for dose 27 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 92 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (K+) at a time period of 0-24 hr for dose 9 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 95 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Cl-) at a time period of 0-5 hr for dose 81 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 96 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (K+) at a time period of 0-24 hr for dose 81 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 104 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Na+) at a time period of 0-5 hr for dose 27 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 135 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Na+) at a time period of 0-5 hr for dose 81 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 139 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (K+) at a time period of 0-24 hr for dose 3 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 203 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Cl-) at a time period of 0-24 hr for dose 3 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 204 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Cl-) at a time period of 0-24 hr for dose 9 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 277 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Cl-) at a time period of 0-24 hr for dose 27 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 281 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Na+) at a time period of 0-24 hr for dose 3 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 296 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Na+) at a time period of 0-24 hr for dose 9 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 326 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Cl-) at a time period of 0-24 hr for dose 81 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 389 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Na+) at a time period of 0-24 hr for dose 27 mg/kg ChEMBL. 3735322
Diuretic effect (functional) = 433 Compound was evaluated for diuretic activity determined by the ability to induce electrolytic excretion (Na+) at a time period of 0-24 hr for dose 81 mg/kg ChEMBL. 3735322
Urine volume (functional) = 25 ml Urine volumes in Sprague-Dawley rats was determined at time period of 0-5 hours at 3 mg/kg ChEMBL. 3735322
Urine volume (functional) = 25 ml Urine volumes in Sprague-Dawley rats was determined at time period of 0-5 hours at 9 mg/kg ChEMBL. 3735322
Urine volume (functional) = 27 ml Urine volumes in Sprague-Dawley rats was determined at time period of 0-5 hours at 27 mg/kg ChEMBL. 3735322
Urine volume (functional) = 29 ml Urine volumes in Sprague-Dawley rats was determined at time period of 0-5 hours at 81 mg/kg ChEMBL. 3735322

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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