Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Bromodomain containing protein | 0.0116 | 0.0581 | 0.1171 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0583 | 0.1174 |
Echinococcus multilocularis | phd:f box containing protein | 0.0045 | 0.0056 | 0.0056 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.02 | 0.1198 | 0.2413 |
Loa Loa (eye worm) | hypothetical protein | 0.0713 | 0.4966 | 1 |
Echinococcus granulosus | phd:f box containing protein | 0.0045 | 0.0056 | 0.0056 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0088 | 0.0378 | 0.0761 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0052 | 0.0108 | 0.0108 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0097 | 0.0195 |
Echinococcus multilocularis | peregrin | 0.0096 | 0.043 | 0.043 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0145 | 0.0791 | 0.0791 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0093 | 0.041 | 0.0825 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0052 | 0.0111 | 0.0224 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0349 | 0.2295 | 0.2295 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0318 | 0.0641 |
Schistosoma mansoni | patched 1 | 0.0294 | 0.1885 | 0.1885 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.1139 | 0.1139 |
Treponema pallidum | hypothetical protein | 0.0291 | 0.1869 | 0.4379 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0073 | 0.0264 | 0.0264 |
Entamoeba histolytica | DNA repair and recombination protein, putative | 0.0063 | 0.0193 | 0.0472 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0057 | 0.0147 | 0.0505 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0057 | 0.0147 | 0.0361 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.0713 | 0.4966 | 0.4966 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0335 | 0.2186 | 0.5359 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0052 | 0.0108 | 0.0108 |
Schistosoma mansoni | jumonji domain containing protein | 0.029 | 0.1859 | 0.1859 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0165 | 0.0938 | 0.0938 |
Echinococcus granulosus | muscleblind protein | 0.0303 | 0.1951 | 0.1951 |
Entamoeba histolytica | hypothetical protein | 0.0106 | 0.0507 | 0.1243 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0303 | 0.1951 | 0.1951 |
Echinococcus multilocularis | lamin dm0 | 0.0082 | 0.0329 | 0.0329 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0192 | 0.1139 | 0.2293 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0166 | 0.0951 | 0.1915 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0056 | 0.0113 |
Echinococcus multilocularis | tar DNA binding protein | 0.0192 | 0.1139 | 0.1139 |
Loa Loa (eye worm) | intermediate filament protein | 0.0082 | 0.0329 | 0.0663 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0145 | 0.0791 | 0.0791 |
Trypanosoma cruzi | DNA repair and recombination helicase protein PIF7, putative | 0.0063 | 0.0193 | 0.0388 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0173 | 0.0998 | 0.0998 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.02 | 0.1198 | 0.2413 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0052 | 0.0108 | 0.0108 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.041 | 0.041 |
Onchocerca volvulus | 0.0145 | 0.0791 | 0.217 | |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0088 | 0.0378 | 0.0378 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0335 | 0.2186 | 0.5359 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0294 | 0.1885 | 0.1885 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0592 | 0.4079 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0068 | 0.0231 | 0.0231 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0039 | 0.0019 | 0.0019 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0289 | 0.1854 | 0.9911 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0111 | 0.0272 |
Brugia malayi | Muscleblind-like protein | 0.0303 | 0.1951 | 0.3928 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1398 | 1 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0082 | 0.0329 | 0.0663 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.02 | 0.1198 | 0.1198 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0088 | 0.0378 | 0.745 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.1139 | 0.1139 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0592 | 0.4079 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0052 | 0.0108 | 0.0108 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0166 | 0.0951 | 0.0951 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.0713 | 0.4966 | 0.4966 |
Onchocerca volvulus | Alhambra homolog | 0.0088 | 0.0378 | 0.0229 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0145 | 0.0791 | 0.1592 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0294 | 0.1885 | 0.3796 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0045 | 0.0056 | 0.0113 |
Brugia malayi | hypothetical protein | 0.0371 | 0.2456 | 0.4945 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0108 | 0.0218 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0052 | 0.0111 | 0.0111 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0045 | 0.0056 | 0.0113 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0592 | 0.4079 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0019 | 0.0037 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0264 | 0.0648 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0057 | 0.0147 | 0.0297 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0116 | 0.0579 | 0.0579 |
Echinococcus granulosus | zinc finger protein | 0.0059 | 0.0165 | 0.0165 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0073 | 0.0264 | 0.0264 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0045 | 0.0056 | 0.0056 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0052 | 0.0111 | 0.0111 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0082 | 0.0329 | 0.0663 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0264 | 0.0648 |
Trypanosoma cruzi | ISWI complex protein | 0.0046 | 0.0069 | 0.014 |
Brugia malayi | jmjC domain containing protein | 0.0173 | 0.0998 | 0.201 |
Schistosoma mansoni | alpha-glucosidase | 0.0143 | 0.0781 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.039 | 0.0785 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.0791 | 0.1592 |
Trypanosoma brucei | DNA repair and recombination helicase protein PIF7 | 0.0063 | 0.0193 | 0.0388 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0145 | 0.0791 | 0.0791 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0294 | 0.1885 | 0.1885 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0088 | 0.0378 | 0.0378 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0097 | 0.0195 |
Echinococcus multilocularis | protein patched | 0.0294 | 0.1885 | 0.1885 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.02 | 0.1198 | 0.2937 |
Schistosoma mansoni | phd/f-box containing protein | 0.0045 | 0.0056 | 0.0056 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0052 | 0.0111 | 0.0224 |
Echinococcus granulosus | tar DNA binding protein | 0.0192 | 0.1139 | 0.1139 |
Brugia malayi | hypothetical protein | 0.0073 | 0.0264 | 0.0532 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0045 | 0.0056 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0008 | 0.0015 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0111 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0959 | 0.1931 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0335 | 0.2186 | 0.5359 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0264 | 0.0648 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0181 | 0.1058 | 0.1058 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0045 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0097 | 0.0195 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0166 | 0.0951 | 0.0951 |
Onchocerca volvulus | Huntingtin homolog | 0.0371 | 0.2456 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0264 | 0.0264 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0044 | 0.005 | 0.0101 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0109 | 0.0529 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.0371 | 0.2456 | 0.4945 |
Brugia malayi | Bromodomain containing protein | 0.0096 | 0.043 | 0.0867 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0073 | 0.0264 | 0.0264 |
Schistosoma mansoni | zinc finger protein | 0.0046 | 0.0069 | 0.0069 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0057 | 0.0147 | 0.0505 |
Leishmania major | hypothetical protein, conserved | 0.0046 | 0.0069 | 0.014 |
Trypanosoma cruzi | DNA repair and recombination helicase protein PIF7, putative | 0.0063 | 0.0193 | 0.0388 |
Brugia malayi | jmjC domain containing protein | 0.0045 | 0.0056 | 0.0113 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0057 | 0.0147 | 0.0297 |
Toxoplasma gondii | exonuclease III APE | 0.0057 | 0.0147 | 0.2908 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0106 | 0.0507 | 0.1243 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.041 | 0.041 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0093 | 0.041 | 0.0825 |
Echinococcus granulosus | geminin | 0.0514 | 0.3501 | 0.3501 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0378 | 0.0761 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0592 | 0.4079 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0008 | 0.0015 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0068 | 0.0231 | 0.0231 |
Schistosoma mansoni | bromodomain containing protein | 0.0192 | 0.1137 | 0.1137 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0045 | 0.0056 | 0.0056 |
Brugia malayi | MAP kinase sur-1 | 0.0052 | 0.0111 | 0.0224 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0044 | 0.005 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.0636 | 0.128 |
Brugia malayi | intermediate filament protein | 0.0082 | 0.0329 | 0.0663 |
Echinococcus multilocularis | muscleblind protein | 0.0303 | 0.1951 | 0.1951 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.02 | 0.1198 | 0.1198 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.0193 | 0.0472 |
Onchocerca volvulus | Huntingtin homolog | 0.0371 | 0.2456 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0592 | 0.4079 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0052 | 0.0108 | 0.0108 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0106 | 0.0507 | 0.2488 |
Trypanosoma brucei | protein kinase, putative | 0.0052 | 0.0111 | 0.0224 |
Brugia malayi | TAR-binding protein | 0.0192 | 0.1139 | 0.2293 |
Loa Loa (eye worm) | hypothetical protein | 0.0303 | 0.1951 | 0.3928 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0294 | 0.1885 | 0.4621 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0109 | 0.0529 | 0.0529 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0052 | 0.0111 | 0.0224 |
Giardia lamblia | Rrm3p helicase | 0.0063 | 0.0193 | 0.0206 |
Plasmodium falciparum | phd finger protein, putative | 0.0088 | 0.0378 | 0.1775 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0592 | 0.4079 | 1 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0713 | 0.4966 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0088 | 0.0378 | 0.1775 |
Brugia malayi | jmjC domain containing protein | 0.0349 | 0.2295 | 0.4622 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.0713 | 0.4966 | 0.4966 |
Loa Loa (eye worm) | ICD-1 protein | 0.0106 | 0.0507 | 0.1021 |
Echinococcus granulosus | lamin dm0 | 0.0082 | 0.0329 | 0.0329 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0111 | 0.0272 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0045 | 0.0056 | 0.0056 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0294 | 0.1885 | 0.1885 |
Schistosoma mansoni | ap endonuclease | 0.0057 | 0.0147 | 0.0147 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0165 | 0.0938 | 0.0938 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0145 | 0.0791 | 0.0791 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0166 | 0.0951 | 0.1915 |
Schistosoma mansoni | hypothetical protein | 0.0514 | 0.3501 | 0.3501 |
Brugia malayi | jmjC domain containing protein | 0.0045 | 0.0056 | 0.0113 |
Schistosoma mansoni | hypothetical protein | 0.0309 | 0.1999 | 0.1999 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0045 | 0.0056 | 0.1103 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0052 | 0.0111 | 0.0111 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0057 | 0.0147 | 0.0297 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0057 | 0.0147 | 0.0297 |
Brugia malayi | Bromodomain containing protein | 0.0227 | 0.1398 | 0.2815 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0349 | 0.2295 | 0.2295 |
Loa Loa (eye worm) | hypothetical protein | 0.0294 | 0.1885 | 0.3796 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.1139 | 0.1139 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0057 | 0.0147 | 0.0147 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0264 | 0.0648 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.005 | 0.0098 | 0.0098 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.02 | 0.1198 | 0.1198 |
Schistosoma mansoni | lamin | 0.0082 | 0.0329 | 0.0329 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0815 | 0.5716 | 0.5716 |
Loa Loa (eye worm) | hypothetical protein | 0.0371 | 0.2456 | 0.4945 |
Leishmania major | PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative | 0.0063 | 0.0193 | 0.0388 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0145 | 0.0791 | 0.0791 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0479 | 0.3247 | 0.3247 |
Brugia malayi | RNA, U transporter 1 | 0.0082 | 0.0334 | 0.0672 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0111 | 0.0272 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.02 | 0.1198 | 0.2413 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0045 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 0.1303 | 0.2624 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.1139 | 0.1139 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0123 | 0.0632 | 0.0632 |
Giardia lamblia | PHD finger protein 15 | 0.0088 | 0.0378 | 0.0672 |
Trypanosoma cruzi | DNA repair and recombination helicase protein PIF6, putative | 0.0063 | 0.0193 | 0.0388 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0098 | 0.0446 | 0.0899 |
Plasmodium vivax | nicotinate-nucleotide adenylyltransferase, putative | 0.0291 | 0.1869 | 1 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0145 | 0.0791 | 0.0791 |
Schistosoma mansoni | zinc finger protein | 0.0059 | 0.0165 | 0.0165 |
Schistosoma mansoni | transcription factor btf3 | 0.0106 | 0.0507 | 0.0507 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0052 | 0.0111 | 0.0224 |
Echinococcus granulosus | transcription factor btf3 | 0.0106 | 0.0507 | 0.0507 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0045 | 0.0056 | 0.0113 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0294 | 0.1885 | 0.1885 |
Echinococcus granulosus | ATP dependent DNA helicase PIF1 | 0.0063 | 0.0193 | 0.0193 |
Schistosoma mansoni | alpha-glucosidase | 0.0143 | 0.0781 | 0.0781 |
Brugia malayi | mbt repeat family protein | 0.0145 | 0.0791 | 0.1592 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0592 | 0.4079 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.1139 | 0.1139 |
Echinococcus granulosus | peregrin | 0.0096 | 0.043 | 0.043 |
Echinococcus multilocularis | musashi | 0.0082 | 0.0329 | 0.0329 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0106 | 0.0507 | 0.1243 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.02 | 0.1198 | 0.2413 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0057 | 0.0147 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0303 | 0.1951 | 0.3928 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0057 | 0.0147 | 0.0297 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0592 | 0.4079 | 1 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0713 | 0.4966 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0088 | 0.0378 | 0.0378 |
Leishmania major | hypothetical protein, conserved | 0.0045 | 0.0056 | 0.0113 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0106 | 0.0507 | 0.1021 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0052 | 0.0108 | 0.0108 |
Echinococcus multilocularis | snurportin 1 | 0.0309 | 0.1999 | 0.1999 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0678 | 0.1365 |
Schistosoma mansoni | jumonji domain containing protein | 0.0045 | 0.0056 | 0.0056 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0188 | 0.0188 |
Brugia malayi | MH2 domain containing protein | 0.0242 | 0.1506 | 0.3032 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0116 | 0.0579 | 0.0579 |
Schistosoma mansoni | lamin | 0.0082 | 0.0329 | 0.0329 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0294 | 0.1885 | 0.1885 |
Mycobacterium leprae | PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC | 0.0291 | 0.1869 | 1 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.0713 | 0.4966 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.041 | 0.041 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0106 | 0.0507 | 0.1243 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0045 | 0.0056 | 0.0113 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0592 | 0.4079 | 1 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0057 | 0.0147 | 0.0092 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0039 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0309 | 0.1999 | 0.4025 |
Echinococcus granulosus | intermediate filament protein | 0.0082 | 0.0329 | 0.0329 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0088 | 0.0378 | 0.745 |
Brugia malayi | jmjC domain containing protein | 0.0045 | 0.0056 | 0.0113 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0057 | 0.0147 | 0.0361 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0173 | 0.0998 | 0.0998 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0335 | 0.2186 | 0.5229 |
Echinococcus multilocularis | ATP dependent DNA helicase PIF1 | 0.0063 | 0.0193 | 0.0193 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0182 | 0.1069 | 0.2152 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0106 | 0.0507 | 0.2488 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0052 | 0.0111 | 0.0224 |
Brugia malayi | mbt repeat family protein | 0.0145 | 0.0791 | 0.1592 |
Mycobacterium tuberculosis | Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic | 0.0291 | 0.1869 | 1 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0052 | 0.0108 | 0.0108 |
Brugia malayi | CHE-14 protein | 0.0294 | 0.1885 | 0.3796 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0329 | 0.0663 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0057 | 0.0147 | 0.0297 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.005 | 0.0098 | 0.0098 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0581 | 0.3997 | 0.3997 |
Echinococcus multilocularis | zinc finger protein | 0.0059 | 0.0165 | 0.0165 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.041 | 0.041 |
Onchocerca volvulus | 0.0096 | 0.0436 | 0.0501 | |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0173 | 0.0998 | 0.201 |
Loa Loa (eye worm) | hypothetical protein | 0.0479 | 0.3247 | 0.6537 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0106 | 0.0507 | 0.1243 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0165 | 0.0938 | 0.0938 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0052 | 0.0111 | 0.0111 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0097 | 0.0195 |
Loa Loa (eye worm) | TAR-binding protein | 0.0192 | 0.1139 | 0.2293 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.041 | 0.041 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0052 | 0.0111 | 0.0111 |
Trypanosoma brucei | DNA repair and recombination helicase protein PIF6 | 0.0063 | 0.0193 | 0.0388 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0145 | 0.0791 | 0.217 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0193 | 0.0193 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0045 | 0.0056 | 0.0113 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1398 | 1 | 1 |
Brugia malayi | PHD-finger family protein | 0.0088 | 0.0378 | 0.0761 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0173 | 0.0998 | 0.0998 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0063 | 0.0188 | 0.0379 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0063 | 0.0193 | 0.0472 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0045 | 0.0056 | 0.0056 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0592 | 0.4079 | 1 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0165 | 0.0938 | 0.1888 |
Echinococcus multilocularis | geminin | 0.0514 | 0.3501 | 0.3501 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0167 | 0.0955 | 0.0955 |
Loa Loa (eye worm) | RNA binding protein | 0.0192 | 0.1139 | 0.2293 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0592 | 0.4079 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.039 | 0.0785 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0052 | 0.0111 | 0.0224 |
Leishmania major | PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative | 0.0063 | 0.0193 | 0.0388 |
Echinococcus granulosus | lamin | 0.0082 | 0.0329 | 0.0329 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0052 | 0.0111 | 0.219 |
Schistosoma mansoni | protein phosphatase 2C | 0.0045 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0056 | 0.0113 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0192 | 0.1139 | 0.2293 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.02 | 0.1198 | 0.2413 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0181 | 0.1058 | 0.1058 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0052 | 0.0111 | 0.0224 |
Brugia malayi | beta-NAC-like protein | 0.0106 | 0.0507 | 0.1021 |
Echinococcus granulosus | jumonji domain containing protein | 0.0123 | 0.0632 | 0.0632 |
Schistosoma mansoni | ap endonuclease | 0.0057 | 0.0147 | 0.0147 |
Brugia malayi | PHD-finger family protein | 0.0075 | 0.0283 | 0.057 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0106 | 0.0507 | 0.1021 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0592 | 0.4079 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0581 | 0.3997 | 0.3997 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.0713 | 0.4966 | 1 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0106 | 0.0507 | 0.1021 |
Brugia malayi | hypothetical protein | 0.009 | 0.039 | 0.0785 |
Mycobacterium ulcerans | bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein | 0.0291 | 0.1869 | 0.3573 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.041 | 0.041 |
Trypanosoma brucei | ISWI complex protein | 0.0046 | 0.0069 | 0.014 |
Trypanosoma cruzi | ISWI complex protein | 0.0046 | 0.0069 | 0.014 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0713 | 0.4966 | 1 |
Echinococcus granulosus | snurportin 1 | 0.0309 | 0.1999 | 0.1999 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0088 | 0.0378 | 0.0378 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0713 | 0.4966 | 1 |
Plasmodium falciparum | nicotinamide/nicotinic acid mononucleotide adenylyltransferase | 0.0291 | 0.1869 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0082 | 0.0329 | 0.0329 |
Schistosoma mansoni | eyes absent homolog | 0.009 | 0.039 | 0.039 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0145 | 0.0791 | 0.0791 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.041 | 0.041 |
Schistosoma mansoni | survival motor neuron protein | 0.0098 | 0.0446 | 0.0446 |
Toxoplasma gondii | NAC domain-containing protein | 0.0106 | 0.0507 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0446 | 0.0446 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0052 | 0.0108 | 0.0108 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.02 | 0.1198 | 0.2413 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0045 | 0.0056 | 0.1103 |
Schistosoma mansoni | hypothetical protein | 0.089 | 0.6268 | 0.6268 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0165 | 0.0938 | 0.0938 |
Leishmania major | basic transcription factor 3a, putative | 0.0106 | 0.0507 | 0.1021 |
Onchocerca volvulus | 0.0098 | 0.0446 | 0.0551 | |
Echinococcus multilocularis | protein dispatched 1 | 0.0294 | 0.1885 | 0.1885 |
Echinococcus multilocularis | transcription factor btf3 | 0.0106 | 0.0507 | 0.0507 |
Brugia malayi | RNA binding protein | 0.0192 | 0.1139 | 0.2293 |
Echinococcus multilocularis | lamin | 0.0082 | 0.0329 | 0.0329 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0068 | 0.0231 | 0.0231 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0479 | 0.3247 | 0.3247 |
Brugia malayi | hypothetical protein | 0.0479 | 0.3247 | 0.6537 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.0938 | 0.1888 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0057 | 0.0147 | 0.0361 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0045 | 0.0056 | 0.0056 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0045 | 0.0056 | 0.0056 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0289 | 0.1854 | 0.3541 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0057 | 0.0147 | 0.0147 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0242 | 0.1506 | 0.3032 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0294 | 0.1885 | 0.1885 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0242 | 0.1506 | 0.3032 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0165 | 0.0938 | 0.0938 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0054 | 0.0122 | 0.0246 |
Loa Loa (eye worm) | MBCTL1 | 0.0165 | 0.0938 | 0.1888 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0166 | 0.0951 | 0.0951 |
Brugia malayi | jmjC domain containing protein | 0.0045 | 0.0056 | 0.0113 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0052 | 0.0111 | 0.0224 |
Schistosoma mansoni | hypothetical protein | 0.0514 | 0.3501 | 0.3501 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.