Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.1914 | 0.5 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.1426 | 0.219 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.3422 | 0.3422 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.3422 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.3422 | 0.5 |
Onchocerca volvulus | 0.0025 | 0.3422 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.6031 | 0.9266 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.3422 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.1426 | 0.219 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.1426 | 0.219 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.3422 | 0.3422 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.3422 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.3422 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.3422 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.1426 | 0.219 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1426 | 0.1426 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.3422 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.1426 | 0.219 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.3422 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.3422 | 0.3422 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.6031 | 0.6031 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.1914 | 0.1914 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.1914 | 0.139 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.3422 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.3422 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.1914 | 0.1914 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.3422 | 0.3422 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.1426 | 0.1426 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.3422 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.3422 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.6509 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.6031 | 0.6031 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.3422 | 0.3422 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.6509 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 1 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.3422 | 0.3422 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.1914 | 0.1914 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.6509 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.1426 | 0.219 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.1426 | 0.219 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.3422 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.1426 | 0.219 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.1914 | 0.1914 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.6509 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.3422 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.3422 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.1426 | 0.219 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.1914 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.6509 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.1914 | 0.1914 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.6509 | 1 |
Brugia malayi | hypothetical protein | 0.0039 | 0.6509 | 0.6509 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.6509 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.6509 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.1426 | 0.1426 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 1 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.1426 | 0.1426 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.1914 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.1426 | 0.219 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.