Detailed information for compound 553763

Basic information

Technical information
  • TDR Targets ID: 553763
  • Name: N-[bis(diethylamino)phosphanyl]-N-ethyl-ethan amine
  • MW: 247.36 | Formula: C12H30N3P
  • H donors: 0 H acceptors: 0 LogP: 2.83 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(P(N(CC)CC)N(CC)CC)CC
  • InChi: 1S/C12H30N3P/c1-7-13(8-2)16(14(9-3)10-4)15(11-5)12-6/h7-12H2,1-6H3
  • InChiKey: FDIOSTIIZGWENY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[bis(diethylamino)phosphino]-N-ethylethanamine
  • bis(diethylamino)phosphino-diethyl-amine
  • N-[bis(diethylamino)phosphanyl]-N-ethylethanamine
  • tris(diethylamino)phosphine
  • N-bis(diethylamino)phosphanyl-N-ethylethanamine
  • N-bis(diethylamino)phosphanyl-N-ethyl-ethanamine
  • bis(diethylamino)phosphanyl-diethyl-amine
  • 2283-11-6
  • 68574-03-8
  • 253189_ALDRICH
  • AI3-50916
  • Phosphorous triamide, hexaethyl-
  • EINECS 218-920-8
  • ZINC00391998
  • FR-0785
  • SBB008031
  • Hexaethylphosphorous triamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis dnaJ subfamily B 0.0433 0.883 0.8828
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0024 0.009
Schistosoma mansoni tar DNA-binding protein 0.0132 0.2611 0.2957
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0007 0.002 0.022
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0007 0.002 0.022
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0728 0.1355
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0133 0.2624 1
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0024 0.004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.6574 1
Mycobacterium tuberculosis Conserved protein 0.0041 0.0728 0.1355
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0024 0.004
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0847 0.1273
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.013 0.2559 0.8125
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0007 0.0024 0.0075
Echinococcus granulosus protein C ets 2 0.0012 0.0108 0.0088
Trypanosoma brucei kinesin, putative 0.002 0.0289 0.3106
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.6574 1
Loa Loa (eye worm) hypothetical protein 0.0007 0.0024 0.0034
Brugia malayi Muscleblind-like protein 0.0323 0.6562 1
Echinococcus multilocularis dna polymerase eta 0.0047 0.085 0.0831
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0263 0.2826
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0292 0.3137
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0007 0.002 0.0078
Trypanosoma brucei calpain-like protein, putative 0.002 0.0289 0.3106
Trypanosoma brucei DNA polymerase eta, putative 0.0047 0.085 0.9141
Brugia malayi tailless protein 0.0016 0.0191 0.0291
Trypanosoma brucei calpain-like protein, putative 0.002 0.0289 0.3106
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0025 0.0005
Leishmania major aldehyde dehydrogenase, putative 0.0007 0.002 0.0078
Brugia malayi Ets-domain containing protein 0.008 0.1517 0.2311
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0191 0.0216
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0011 0.00000000027283
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0007 0.002 0.0078
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0007 0.0024 0.001
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0007 0.002 0.0065
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.1209 0.1191
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0011 0.009 0.0969
Mycobacterium tuberculosis Probable reductase 0.0117 0.2289 0.4271
Brugia malayi TAR-binding protein 0.0132 0.2611 0.3979
Loa Loa (eye worm) hypothetical protein 0.0033 0.0552 0.0808
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0117 0.2289 0.4271
Onchocerca volvulus 0.0016 0.0191 0.2033
Loa Loa (eye worm) hypothetical protein 0.0017 0.023 0.0336
Brugia malayi beta-lactamase family protein 0.0041 0.0728 0.1109
Echinococcus multilocularis calpain 0.002 0.0289 0.0269
Brugia malayi calpain 5 0.002 0.0289 0.044
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0024 0.0036
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0765 0.8231
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0253 0.0233
Echinococcus granulosus ferritin 0.0027 0.0424 0.0404
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0253 0.0233
Echinococcus multilocularis neuropeptide s receptor 0.0489 1 1
Brugia malayi beta-lactamase family protein 0.0041 0.0728 0.1109
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0303 0.0283
Brugia malayi RNA, U transporter 1 0.009 0.1724 0.2627
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0728 0.2264
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0033 0.0552 0.0533
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0236 0.5356
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0303 0.3259
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0292 0.3137
Echinococcus multilocularis geminin 0.0188 0.3756 0.3743
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0728 0.2314
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0139 0.0211
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0236 0.036
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0072 0.1352 0.1335
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0007 0.002 0.0023
Onchocerca volvulus 0.0041 0.0728 0.8421
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0292 0.3137
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0292 0.0541
Loa Loa (eye worm) hypothetical protein 0.0323 0.6562 0.9603
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0303 0.1154
Schistosoma mansoni coup transcription factor 0.0033 0.0552 0.0625
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0033 0.0552 0.0841
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0033 0.0552 0.0808
Trichomonas vaginalis ran, putative 0.0023 0.0349 0.0514
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0303 0.1154
Schistosoma mansoni tar DNA-binding protein 0.0132 0.2611 0.2957
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.1142 0.4352
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.016 0.1725
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0292 0.3137
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0072 0.1352 0.1531
Brugia malayi nuclear receptor RXR 0.0017 0.023 0.035
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0007 0.002 0.022
Loa Loa (eye worm) hypothetical protein 0.0025 0.0396 0.0579
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0007 0.002 0.022
Schistosoma mansoni nuclear receptor 0.0016 0.0191 0.0216
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0033 0.0558 0.2127
Echinococcus multilocularis cpg binding protein 0.0032 0.0534 0.0514
Brugia malayi nuclear hormone receptor family member odr-7 0.0016 0.0191 0.0291
Loa Loa (eye worm) hypothetical protein 0.0068 0.128 0.1873
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0011 0.00000000027283
Brugia malayi hypothetical protein 0.0078 0.1476 0.2249
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0016 0.0191 0.0291
Brugia malayi Fli-1 protein 0.0242 0.4872 0.7424
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0007 0.002 0.022
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0292 0.3137
Leishmania major DNA polymerase kappa, putative 0.002 0.0292 0.1111
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0217 0.0197
Schistosoma mansoni ferritin 0.0027 0.0424 0.048
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0007 0.002 0.0034
Loa Loa (eye worm) hypothetical protein 0.0033 0.0552 0.0808
Echinococcus multilocularis ecdysone induced protein 78C 0.0033 0.0552 0.0533
Schistosoma mansoni ferritin light chain 0.0027 0.0424 0.048
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0217 0.0317
Brugia malayi calpain family protein 1 0.0068 0.128 0.1951
Brugia malayi beta-lactamase 0.0041 0.0728 0.1109
Echinococcus multilocularis neuropeptide receptor A26 0.0489 1 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0303 0.3259
Plasmodium falciparum glutathione reductase 0.0051 0.093 1
Echinococcus granulosus cpg binding protein 0.0032 0.0534 0.0514
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0552 0.0841
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0025 0.0028
Echinococcus multilocularis expressed protein 0.0027 0.0424 0.0404
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0024 0.004
Trichomonas vaginalis esterase, putative 0.0041 0.0728 0.1091
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0552 0.0841
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0024 0.004
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0135 0.2668 0.2653
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.093 0.1732
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0847 0.3226
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0033 0.0552 0.0841
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0728 0.7828
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0016 0.0191 0.0216
Echinococcus multilocularis snurportin 1 0.0336 0.6834 0.6827
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0292 0.3137
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0033 0.0552 0.0841
Brugia malayi orphan nuclear receptor NR2E1 0.0016 0.0191 0.0291
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0007 0.0024 0.0075
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0016 0.0191 0.0216
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.1918 0.1902
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0292 0.0272
Loa Loa (eye worm) hypothetical protein 0.0033 0.0552 0.0808
Trypanosoma cruzi calpain cysteine peptidase, putative 0.002 0.0289 0.3106
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0007 0.002 0.0078
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0728 0.1091
Brugia malayi Ets-domain containing protein 0.008 0.1517 0.2311
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.6574 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0289 0.3106
Schistosoma mansoni zinc finger protein 0.0016 0.0191 0.0216
Echinococcus granulosus nuclear receptor nhr 48 0.0016 0.0191 0.0171
Plasmodium vivax glutathione reductase, putative 0.0051 0.093 1
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0292 0.3137
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0349 0.3754
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0552 0.0533
Loa Loa (eye worm) oxidoreductase 0.0007 0.0024 0.0034
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0158 0.3144 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0068 0.128 0.145
Loa Loa (eye worm) hypothetical protein 0.0041 0.0728 0.1065
Trypanosoma cruzi kinesin, putative 0.002 0.0289 0.3106
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0728 0.7828
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0217 0.0245
Echinococcus multilocularis muscleblind protein 0.0323 0.6562 0.6555
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0024 0.0034
Brugia malayi DNA-binding protein D-ETS-3 0.0012 0.0108 0.0164
Loa Loa (eye worm) D-ets-2 protein 0.0012 0.0108 0.0158
Loa Loa (eye worm) hypothetical protein 0.0025 0.0396 0.0579
Brugia malayi transcription factor E74 isoform 0.0012 0.0108 0.0164
Mycobacterium ulcerans lipase LipD 0.0041 0.0728 0.2314
Brugia malayi jmjC domain containing protein 0.0017 0.0217 0.033
Mycobacterium tuberculosis Probable oxidoreductase 0.013 0.2559 0.4775
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0236 0.5356
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0303 0.0283
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Loa Loa (eye worm) hypothetical protein 0.0007 0.0024 0.0034
Onchocerca volvulus 0.0041 0.0728 0.8421
Loa Loa (eye worm) hypothetical protein 0.0017 0.0217 0.0317
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0847 0.1273
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0007 0.0024 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0191 0.0171
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0117 0.2289 0.7261
Leishmania major importin beta-1 subunit, putative 0.0026 0.0398 0.1516
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0728 0.1091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0011 0.00000000027283
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Brugia malayi Steroid receptor seven-up type 2 0.0033 0.0552 0.0841
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0498 0.0729
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.1918 0.1902
Trypanosoma brucei unspecified product 0.002 0.0292 0.3137
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0292 0.0427
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.008 0.1517 0.222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0033 0.0552 0.0808
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0349 0.0511
Brugia malayi acetyltransferase, GNAT family protein 0.0161 0.3194 0.4867
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0024 0.0036
Loa Loa (eye worm) RNA binding protein 0.0132 0.2611 0.3821
Echinococcus granulosus FTZ F1 alpha 0.0033 0.0552 0.0533
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0024 0.0075
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0117 0.2289 0.4271
Onchocerca volvulus 0.0007 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.0108 0.0158
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0007 0.002 0.0031
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0236 0.2543
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0292 0.033
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.023 0.035
Loa Loa (eye worm) hypothetical protein 0.0033 0.0552 0.0808
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0303 0.0444
Echinococcus granulosus expressed protein 0.0027 0.0424 0.0404
Schistosoma mansoni calpain-7 (C02 family) 0.0024 0.0356 0.0403
Schistosoma mansoni apoferritin-2 0.0027 0.0424 0.048
Brugia malayi nuclear receptor RXR 0.0016 0.0191 0.0291
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.1209 0.137
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Echinococcus multilocularis ferritin 0.0027 0.0424 0.0404
Echinococcus granulosus tar DNA binding protein 0.0132 0.2611 0.2596
Plasmodium falciparum thioredoxin reductase 0.0018 0.0236 0.2543
Onchocerca volvulus 0.0033 0.0552 0.6332
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0217 0.0317
Schistosoma mansoni ran 0.0023 0.0349 0.0395
Echinococcus multilocularis ETS transcription factor Elf 5 0.0012 0.0108 0.0088
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.013 0.2559 0.4775
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0728 0.1355
Loa Loa (eye worm) calpain family protein 1 0.0048 0.086 0.1259
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.1918 0.2807
Echinococcus granulosus GA binding protein alpha chain 0.008 0.1517 0.1499
Schistosoma mansoni cpg binding protein 0.0032 0.0534 0.0605
Loa Loa (eye worm) hypothetical protein 0.0019 0.0263 0.0384
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0236 0.0901
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0033 0.0552 0.0625
Loa Loa (eye worm) calpain 5 0.002 0.0289 0.0423
Loa Loa (eye worm) hypothetical protein 0.0007 0.002 0.003
Loa Loa (eye worm) nuclear receptor NHR-67 0.0016 0.0191 0.028
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.1918 0.1902
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0303 0.0462
Brugia malayi hypothetical protein 0.0016 0.0191 0.0291
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0033 0.0552 0.0808
Schistosoma mansoni nuclear receptor 0.0016 0.0191 0.0216
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0024 0.0075
Entamoeba histolytica recQ family DNA helicase 0.0011 0.009 0.0106
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0396 0.0736
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.002 0.0023
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0521 0.5607
Onchocerca volvulus 0.0007 0.0024 0.0038
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0033 0.0552 0.0533
Schistosoma mansoni apoferritin-2 0.0027 0.0424 0.048
Leishmania major aldehyde dehydrogenase, putative 0.0007 0.002 0.0078
Echinococcus multilocularis ETS transcription factor Elf 1 0.0012 0.0108 0.0088
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0217 0.0245
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0396 0.1202
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0236 0.2543
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0558 0.6004
Brugia malayi jmjC domain containing protein 0.0017 0.0217 0.033
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0552 0.0841
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0082 0.0311
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.002 0.0289 0.3106
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0191 0.0216
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.093 1
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0007 0.002 0.0078
Mycobacterium ulcerans hypothetical protein 0.0025 0.0396 0.1259
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0011 0.00000000027283
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0292 0.1111
Giardia lamblia Fructose-bisphosphate aldolase 0.0324 0.6574 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0241 0.0447
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0324 0.6574 1
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0728 0.1091
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0847 0.3226
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0552 0.0533
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0191 0.0291
Brugia malayi RNA recognition motif domain containing protein 0.0132 0.2611 0.3979
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0011 0.00000000027283
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.0236 0.0752
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0012 0.0108 0.0158
Schistosoma mansoni transcription factor LCR-F1 0.0078 0.1476 0.1671
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0292 0.3137
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0016 0.0191 0.028
Brugia malayi nuclear receptor NHR-88 0.0016 0.0191 0.0291
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.6574 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0007 0.002 0.0034
Brugia malayi ImpB/MucB/SamB family protein 0.0047 0.085 0.1295
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.0303 0.0443
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.023 0.026
Loa Loa (eye worm) acetyltransferase 0.0161 0.3194 0.4674
Schistosoma mansoni importin beta-1 0.0031 0.0521 0.059
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0396 0.1259
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.009 0.0343
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0289 0.3106
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.0236 0.0343
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0396 0.0603
Schistosoma mansoni tar DNA-binding protein 0.0132 0.2611 0.2957
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0236 0.0901
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.1918 0.2173
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0728 0.1065
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0217 0.0245
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0007 0.002 0.0065
Echinococcus multilocularis protein C ets 2 0.0012 0.0108 0.0088
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0236 0.0216
Loa Loa (eye worm) TAR-binding protein 0.0132 0.2611 0.3821
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0349 0.3754
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0033 0.0552 0.0533
Brugia malayi calpain 7 0.002 0.0289 0.044
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0024 0.0036
Mycobacterium tuberculosis Conserved protein 0.0041 0.0728 0.1355
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0072 0.1352 0.1531
Brugia malayi glutathione reductase 0.0051 0.093 0.1416
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0007 0.002 0.022
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.0236 0.0343
Loa Loa (eye worm) hypothetical protein 0.0019 0.0263 0.0384
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0292 0.3137
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0191 0.0171
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0024 0.0075
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0007 0.002 0.0065
Mycobacterium ulcerans bacterioferritin BfrA 0.0027 0.0424 0.1347
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0552 0.0841
Loa Loa (eye worm) hypothetical protein 0.0017 0.023 0.0336
Loa Loa (eye worm) beta-lactamase 0.0041 0.0728 0.1065
Echinococcus multilocularis thyroid hormone receptor alpha 0.0168 0.3352 0.3338
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0396 0.0603
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0396 0.0736
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0263 0.2826
Schistosoma mansoni thyroid hormone receptor 0.0168 0.3352 0.3796
Onchocerca volvulus 0.003 0.0498 0.5687
Entamoeba histolytica hypothetical protein 0.0026 0.0398 0.0576
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0007 0.002 0.0065
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0303 0.0444
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0061 0.0093
Loa Loa (eye worm) hypothetical protein 0.0017 0.023 0.0336
Loa Loa (eye worm) calpain family protein 1 0.0068 0.128 0.1873
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.1918 0.1902
Loa Loa (eye worm) hypothetical protein 0.0041 0.0728 0.1065
Echinococcus granulosus calpain A 0.002 0.0289 0.0269
Echinococcus granulosus neuropeptide receptor A26 0.0489 1 1
Echinococcus multilocularis dna polymerase kappa 0.002 0.0292 0.0272
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0007 0.002 0.0034
Giardia lamblia DINP protein human, muc B family 0.002 0.0292 0.0444
Entamoeba histolytica Ran family GTPase 0.0023 0.0349 0.0501
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0289 0.3106
Treponema pallidum NADH oxidase 0.0018 0.0236 0.033
Schistosoma mansoni DNA helicase recq5 0.0021 0.0303 0.0343
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0236 0.2543
Brugia malayi ecdysone receptor 0.0016 0.0191 0.0291
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0396 0.1259
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0117 0.2289 0.4271
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0007 0.002 0.0078
Schistosoma mansoni ran 0.0023 0.0349 0.0395
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.6574 1
Echinococcus granulosus phd:f box containing protein 0.0017 0.0217 0.0197
Trypanosoma brucei unspecified product 0.0014 0.016 0.1725
Echinococcus granulosus histone acetyltransferase KAT2B 0.0156 0.3101 0.3086
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0349 0.3754
Schistosoma mansoni tar DNA-binding protein 0.0132 0.2611 0.2957
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0007 0.002 0.022
Leishmania major acetyl-CoA synthetase, putative 0.0007 0.0024 0.009
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0217 0.0826
Plasmodium vivax importin-beta 2, putative 0.0031 0.0521 0.5607
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0024 0.0036
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0024 0.0019
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0303 0.0462
Brugia malayi Aldehyde dehydrogenase protein 4 0.0007 0.002 0.0031
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0007 0.002 0.003
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0033 0.0552 0.0841
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0236 0.2543
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0063 0.0093
Schistosoma mansoni elf1 0.0012 0.0108 0.0122
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0303 0.0283
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0396 0.1259
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0007 0.002 0.022
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0024 0.0075
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0303 0.0431
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0024 0.0253
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.023 0.021
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.0236 0.0438
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0024 0.0027
Brugia malayi hypothetical protein 0.0017 0.023 0.035
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0521 0.5607
Echinococcus granulosus calpain 7 C02 family 0.002 0.0289 0.0269
Schistosoma mansoni tar DNA-binding protein 0.0132 0.2611 0.2957
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0024 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0728 0.7828
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0007 0.002 0.022
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0324 0.6574 1
Echinococcus granulosus ETS transcription factor Elf 2 0.0012 0.0108 0.0088
Loa Loa (eye worm) hypothetical protein 0.0068 0.128 0.1873
Loa Loa (eye worm) ets-domain-containing protein 0.0012 0.0108 0.0158
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0236 0.2543
Loa Loa (eye worm) hypothetical protein 0.0017 0.0217 0.0317
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0336 0.6834 1
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0292 0.0927
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0007 0.002 0.022
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0007 0.002 0.0014
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.002 0.0023
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0303 0.0444
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0007 0.002 0.0065
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.023 0.026
Brugia malayi RNA binding protein 0.0132 0.2611 0.3979
Schistosoma mansoni calpain-7 (C02 family) 0.0024 0.0356 0.0403
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0024 0.0036
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0007 0.0024 0.0005
Mycobacterium ulcerans hypothetical protein 0.0041 0.0728 0.2314
Schistosoma mansoni retinoic acid receptor RXR 0.0033 0.0552 0.0625
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0024 0.004
Echinococcus multilocularis ets variant gene 4 0.0012 0.0108 0.0088
Leishmania major kinesin, putative 0.002 0.0289 0.11
Brugia malayi steroid hormone receptor 0.0033 0.0552 0.0841
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0728 0.1091
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0292 0.3137
Brugia malayi nuclear receptor NHR-67 0.0016 0.0191 0.0291
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0292 0.0927
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0033 0.0552 0.0533
Echinococcus granulosus ETS transcription factor Elf 1 0.0012 0.0108 0.0088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.1918 0.2173
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0007 0.002 0.022
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.009 0.0969
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0072 0.1352 0.1335
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0217 0.0197
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0728 0.0824
Brugia malayi calpain family protein 1 0.0068 0.128 0.1951
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0016 0.0191 0.0171
Loa Loa (eye worm) hypothetical protein 0.0041 0.0728 0.1065
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0217 0.0197
Entamoeba histolytica hypothetical protein 0.0078 0.1476 0.2221
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0191 0.0291
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.2624 0.8347
Mycobacterium leprae Probable lipase LipE 0.0041 0.0728 0.2264
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0024 0.0253
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.0236 0.0752
Brugia malayi jmjC domain containing protein 0.0065 0.1209 0.1843
Mycobacterium tuberculosis Probable dehydrogenase 0.0117 0.2289 0.4271
Loa Loa (eye worm) hypothetical protein 0.0033 0.0552 0.0808
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.0236 0.0752
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0292 0.3137
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0007 0.002 0.0078
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0552 0.0841
Toxoplasma gondii thioredoxin reductase 0.0051 0.093 0.3542
Onchocerca volvulus 0.0007 0.0024 0.0038
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0728 0.1355
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0027 0.0424 0.0787
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0217 0.0826
Schistosoma mansoni ferritin light chain 0.0027 0.0424 0.048
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.0303 0.0461
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0728 0.0709
Loa Loa (eye worm) hypothetical protein 0.0323 0.6562 0.9603
Brugia malayi conserved hypotetical protein 0.0016 0.0191 0.0291
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0552 0.0533
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0007 0.002 0.0065
Loa Loa (eye worm) calpain 0.002 0.0289 0.0423
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0024 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0303 0.0443
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0007 0.002 0.0065
Trypanosoma brucei trypanothione reductase 0.0051 0.093 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0033 0.0552 0.0533
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0292 0.3137
Onchocerca volvulus Bile acid receptor homolog 0.0033 0.0552 0.6332
Entamoeba histolytica calpain large subunit domain III containing protein 0.002 0.0289 0.0409
Echinococcus granulosus calpain A 0.0072 0.1352 0.1335
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.1918 0.2173
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0007 0.0024 0.0253
Schistosoma mansoni ferritin 0.0027 0.0424 0.048
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0396 0.1259
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0265 0.5356 1
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0024 0.004
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0521 0.0502
Schistosoma mansoni jumonji domain containing protein 0.0063 0.1174 0.1329
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0139 0.0211
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0217 0.0197
Loa Loa (eye worm) hypothetical protein 0.0068 0.1278 0.187
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0033 0.0552 0.0625
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0398 0.0589
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0117 0.2289 0.4271
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0033 0.0552 0.0841
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0396 0.1259
Echinococcus granulosus geminin 0.0188 0.3756 0.3743
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.1209 0.137
Schistosoma mansoni hypothetical protein 0.0188 0.3756 0.4254
Entamoeba histolytica hypothetical protein 0.0078 0.1476 0.2221
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0552 0.0625
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0041 0.0728 0.1065
Echinococcus multilocularis tar DNA binding protein 0.0132 0.2611 0.2596
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0349 0.133
Brugia malayi jmjC domain containing protein 0.0063 0.1174 0.1788
Loa Loa (eye worm) hypothetical protein 0.0011 0.009 0.0132
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0289 0.3106
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0292 0.3137
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0847 0.9108
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0728 0.7828
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0728 0.1355
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0007 0.002 0.022
Plasmodium vivax calpain, putative 0.002 0.0289 0.3106
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0728 0.1355
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0236 0.0901
Brugia malayi CXXC zinc finger family protein 0.003 0.0498 0.0759
Schistosoma mansoni cpg binding protein 0.0032 0.0534 0.0605
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0132 0.2611 0.3821
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0007 0.0024 0.0253
Schistosoma mansoni ets 0.0012 0.0108 0.0122
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0241 0.0447
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0007 0.0024 0.001
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.009 0.0969
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0236 0.2543
Schistosoma mansoni calpain (C02 family) 0.002 0.0289 0.0327
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0007 0.002 0.0031
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0236 0.0901
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0765 0.1136
Brugia malayi Importin beta-1 subunit 0.0031 0.0521 0.0794
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0024 0.004
Plasmodium vivax acetyl-CoA synthetase, putative 0.0007 0.0024 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0033 0.0552 0.0841
Schistosoma mansoni Mername-AA248 (C02 family) 0.002 0.0289 0.0327
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0033 0.0552 0.0625
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0007 0.002 0.022
Loa Loa (eye worm) hypothetical protein 0.0041 0.0728 0.1065
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0007 0.002 0.0034
Echinococcus multilocularis hypothetical protein 0.002 0.0289 0.0269
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0292 0.0444
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0303 0.3259
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0292 0.3137
Brugia malayi nuclear hormone receptor family member nhr-6 0.0016 0.0191 0.0291
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0012 0.0108 0.0122
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.6574 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0728 0.0824
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0024 0.0075
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0236 0.2543
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0063 0.0043
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0263 0.0487
Loa Loa (eye worm) hypothetical protein 0.0017 0.023 0.0336
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.1174 0.1155
Loa Loa (eye worm) hypothetical protein 0.0012 0.0108 0.0158
Treponema pallidum fructose-bisphosphate aldolase 0.0324 0.6574 1
Brugia malayi nuclear hormone receptor 0.0016 0.0191 0.0291
Loa Loa (eye worm) hypothetical protein 0.0017 0.023 0.0336
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0007 0.002 0.022
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0007 0.002 0.0034
Brugia malayi nuclear hormone receptor 0.0033 0.0552 0.0841
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0349 0.0531
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0024 0.0075
Echinococcus granulosus dna polymerase kappa 0.002 0.0292 0.0272
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0007 0.0024 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0292 0.3137
Entamoeba histolytica hypothetical protein 0.0078 0.1476 0.2221
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0289 0.3106
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.1174 0.1155
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0398 0.0589
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.6574 1
Schistosoma mansoni calpain C (C02 family) 0.002 0.0289 0.0327
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0236 0.0901
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0303 0.1154
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0292 0.0272
Brugia malayi hypothetical protein 0.0017 0.023 0.035
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.2624 0.2972
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0289 0.3106
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0236 0.0216
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0236 0.2543
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0236 0.2543
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0217 0.0197
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.0303 0.3259
Echinococcus granulosus dna polymerase eta 0.0047 0.085 0.0831
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0728 0.1091
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0191 0.0171
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0024 0.004
Echinococcus granulosus ETS transcription factor Elf 2 0.0012 0.0108 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.016 0.1725
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0024 0.0036
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0016 0.0191 0.0171
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.093 0.0911
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0033 0.0552 0.0533
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0349 0.0329
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0007 0.002 0.0065
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0396 0.1259
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0217 0.0197
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.001 0.0082 0.0879
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.2624 0.8347
Leishmania major acetyl-CoA synthetase, putative 0.0007 0.0024 0.009
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0217 0.2331
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0396 0.1509
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0033 0.0552 0.0808
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0396 0.0603
Echinococcus granulosus ETS domain containing protein Elk 1 0.0012 0.0108 0.0088
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0241 0.0447
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0236 0.2543
Leishmania major DNA polymerase eta, putative 0.0047 0.085 0.3238
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.009 0.0102
Schistosoma mansoni hypothetical protein 0.0336 0.6834 0.7739
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0133 0.2624 0.4898
Trypanosoma brucei antigen, putative 0.002 0.0289 0.3106
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0303 0.0283
Loa Loa (eye worm) hypothetical protein 0.0019 0.0263 0.0384
Entamoeba histolytica recQ family helicase, putative 0.001 0.0082 0.0093
Schistosoma mansoni hypothetical protein 0.0007 0.002 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0033 0.0552 0.0841
Echinococcus granulosus dnaJ subfamily B 0.0433 0.883 0.8828
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0236 0.2543
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0349 0.0532
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0191 0.2033
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0063 0.0043
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0236 0.2543
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0191 0.2033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0241 0.0447
Schistosoma mansoni ets-related 0.0012 0.0108 0.0122
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0191 0.0171
Leishmania major aldehyde dehydrogenase, putative 0.0007 0.002 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0552 0.0841
Treponema pallidum ATP-dependent DNA helicase 0.0011 0.009 0.0106
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0289 0.3106
Schistosoma mansoni hypothetical protein 0.0135 0.2668 0.3022
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0024 0.004
Schistosoma mansoni DNA helicase recq1 0.0021 0.0303 0.0343
Loa Loa (eye worm) fli-1 protein 0.0242 0.4872 0.7129
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0007 0.002 0.0034
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.002 0.0289 0.11
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.002 0.0289 0.11
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0765 0.1164
Schistosoma mansoni hypothetical protein 0.0012 0.0108 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0292 0.3137
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0012 0.0108 0.0088
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0303 0.0283
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.085 0.9141
Loa Loa (eye worm) steroid hormone receptor 0.0033 0.0552 0.0808
Giardia lamblia Alcohol dehydrogenase 0.0007 0.002 0.0031
Leishmania major trypanothione reductase 0.0051 0.093 0.3542
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0007 0.002 0.0034
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0191 0.0171
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0263 0.0836
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0728 0.1109
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0292 0.0427
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0007 0.0024 0.0075
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.002 0.0023
Brugia malayi nuclear receptor NHR-88 0.0033 0.0552 0.0841
Echinococcus granulosus calpain 0.002 0.0289 0.0269
Trypanosoma brucei calpain-like protein, putative 0.002 0.0289 0.3106
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0027 0.0424 0.1291
Echinococcus multilocularis ewsr:fli fusion protein type 0.0012 0.0108 0.0088
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0078 0.1476 0.1458
Plasmodium falciparum glutathione reductase 0.0018 0.0236 0.2543
Schistosoma mansoni hypothetical protein 0.0188 0.3756 0.4254
Brugia malayi Thioredoxin reductase 0.0051 0.093 0.1416
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0161 0.3194 0.318
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0033 0.0552 0.0625
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0349 0.0329
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0396 0.1509
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0236 0.2543
Loa Loa (eye worm) hypothetical protein 0.0017 0.0217 0.0317
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0728 0.0709
Echinococcus granulosus ewsr:fli fusion protein type 0.0012 0.0108 0.0088
Toxoplasma gondii aldehyde dehydrogenase 0.0133 0.2624 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.086 0.1259
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0078 0.1476 0.1458
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0396 0.0573
Brugia malayi jmjC domain containing protein 0.0017 0.0217 0.033
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0007 0.002 0.0065
Echinococcus granulosus muscleblind protein 0.0323 0.6562 0.6555
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0728 0.1355
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0292 0.0427
Onchocerca volvulus 0.0016 0.0191 0.2033
Toxoplasma gondii propionate-CoA ligase 0.0007 0.0024 0.009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0007 0.002 0.0065
Schistosoma mansoni ets-related 0.0242 0.4872 0.5518
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0728 0.2314
Echinococcus granulosus thyroid hormone receptor alpha 0.0016 0.0191 0.0171
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0007 0.0024 0.0075
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0007 0.0024 0.009
Mycobacterium ulcerans beta-lactamase 0.0041 0.0728 0.2314
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0847 0.0828
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0289 0.3106
Echinococcus granulosus ecdysone induced protein 78C 0.0033 0.0552 0.0533
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0396 0.1259
Loa Loa (eye worm) hypothetical protein 0.0019 0.0263 0.0384
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0217 0.2331
Loa Loa (eye worm) hypothetical protein 0.0007 0.002 0.003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.1203 0.1363
Loa Loa (eye worm) hypothetical protein 0.0033 0.0552 0.0808
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0133 0.2624 0.2609
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0025 0.0005
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0521 0.1986
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.023 0.0336
Loa Loa (eye worm) RecQ helicase 0.0021 0.0303 0.0443
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0007 0.002 0.0065
Leishmania major hypothetical protein, conserved 0.0041 0.0728 0.2772
Schistosoma mansoni hypothetical protein 0.0433 0.883 1
Onchocerca volvulus 0.0041 0.0728 0.8421
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Loa Loa (eye worm) hypothetical protein 0.0047 0.085 0.1243
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0161 0.3194 0.3617
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0236 0.0268
Echinococcus granulosus importin subunit beta 1 0.0031 0.0521 0.0502
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0024 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.009 0.0132
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0024 0.004
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0396 0.1202
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0133 0.2624 0.2609
Plasmodium vivax JmjC domain containing protein 0.0017 0.0217 0.2331
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0033 0.0552 0.0808
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0236 0.2543
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.023 0.035
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Loa Loa (eye worm) hypothetical protein 0.0033 0.0552 0.0808
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0217 0.0197
Echinococcus granulosus ETS transcription factor Elf 5 0.0012 0.0108 0.0088
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0024 0.0019
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0398 0.428
Schistosoma mansoni gabp alpha 0.008 0.1517 0.1718
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0007 0.002 0.0065
Echinococcus multilocularis FTZ F1 alpha 0.0033 0.0552 0.0533
Onchocerca volvulus Protein ultraspiracle homolog 0.0033 0.0552 0.6332
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0025 0.0005
Brugia malayi hypothetical protein 0.0016 0.0191 0.0291
Mycobacterium ulcerans bacterioferritin BfrB 0.0027 0.0424 0.1347
Loa Loa (eye worm) glutathione reductase 0.0051 0.093 0.136
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.002 0.0289 0.11
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.1174 0.1155
Loa Loa (eye worm) nuclear hormone receptor 0.0016 0.0191 0.028
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.016 0.1725
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0007 0.002 0.0065
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0217 0.0245
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0007 0.002 0.0065
Schistosoma mansoni ferritin 0.0027 0.0424 0.048
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0396 0.1509
Schistosoma mansoni steroid hormone receptor ad4bp 0.0033 0.0552 0.0625
Leishmania major GTP-binding protein, putative 0.0023 0.0349 0.133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0011 0.00000000027283
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0236 0.0901
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0033 0.0552 0.0808
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0024 0.004
Brugia malayi jmjC domain containing protein 0.0017 0.0217 0.033
Leishmania major hypothetical protein, conserved 0.0017 0.0217 0.0826
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0027 0.0424 0.0787
Loa Loa (eye worm) hypothetical protein 0.0016 0.0191 0.028
Schistosoma mansoni DNA polymerase eta 0.0047 0.085 0.0962
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0082 0.0092
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0025 0.0005
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0033 0.0552 0.0533
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0024 0.0075
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0024 0.0253
Brugia malayi aldehyde dehydrogenase 0.0007 0.002 0.0031
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0024 0.0253
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.1209 0.177
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0292 0.0541
Echinococcus multilocularis calpain A 0.0072 0.1352 0.1335
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0135 0.2668 0.2653
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0552 0.0625
Loa Loa (eye worm) DR-78 0.0016 0.0191 0.028
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0007 0.0024 0.0075
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0217 0.0245
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.2624 0.8347
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0033 0.0552 0.0625
Mycobacterium ulcerans acetyl-CoA synthetase 0.0007 0.0024 0.0075
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0292 0.3137
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0349 0.3754
Plasmodium falciparum importin beta, putative 0.0031 0.0521 0.5607
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0007 0.002 0.0034
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0552 0.0533
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0024 0.0075
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0007 0.002 0.0034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0011 0.00000000027283
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0303 0.0462
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0728 0.1355
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0217 0.0317
Brugia malayi Ets-domain containing protein 0.0012 0.0108 0.0164
Loa Loa (eye worm) hypothetical protein 0.0041 0.0728 0.1065
Loa Loa (eye worm) hypothetical protein 0.0019 0.0263 0.0384
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.093 1
Toxoplasma gondii ABC1 family protein 0.0041 0.0728 0.2772
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0007 0.002 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0011 0.00000000027283
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0552 0.0841
Onchocerca volvulus 0.0048 0.086 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0033 0.0552 0.6332
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0398 0.0589
Leishmania major DNA polymerase eta, putative 0.0033 0.0558 0.2127
Echinococcus multilocularis muscleblind protein 1 0.0323 0.6562 0.6555
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0263 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0396 0.0579
Echinococcus granulosus bloom syndrome protein 0.0021 0.0303 0.0283
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0217 0.2331
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0007 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0031 0.0521 0.0763
Trypanosoma cruzi kinesin, putative 0.002 0.0289 0.3106
Echinococcus multilocularis ETS transcription factor Elf 2 0.0012 0.0108 0.0088
Schistosoma mansoni thyroid hormone receptor 0.0168 0.3352 0.3796
Schistosoma mansoni hypothetical protein 0.0012 0.0108 0.0122
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0027 0.0424 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.6574 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0292 0.0414
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.093 0.136
Echinococcus multilocularis ETS transcription factor Elf 2 0.0012 0.0108 0.0088
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.002 0.0289 0.3106
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0292 0.033
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.023 0.021
Loa Loa (eye worm) hypothetical protein 0.0033 0.0552 0.0808
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0191 0.0171
Schistosoma mansoni hypothetical protein 0.0078 0.1476 0.1671
Trypanosoma brucei unspecified product 0.0014 0.016 0.1725
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0158 0.3144 1
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0007 0.0024 0.0075
Brugia malayi ecdysteroid receptor 0.0033 0.0552 0.0841
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0033 0.0552 0.0533
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0024 0.0253
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0033 0.0552 0.0808
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0033 0.0552 0.0533
Echinococcus multilocularis GA binding protein alpha chain 0.008 0.1517 0.1499
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.013 0.2559 0.4775
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0158 0.3144 0.5869
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0007 0.0024 0.009
Schistosoma mansoni RAR-like nuclear receptor 0.0033 0.0552 0.0625
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0396 0.0573
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0007 0.002 0.022
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.093 0.0911
Mycobacterium tuberculosis Conserved protein 0.0041 0.0728 0.1355
Schistosoma mansoni cpg binding protein 0.003 0.0498 0.0564
Echinococcus multilocularis calpain 7 (C02 family) 0.002 0.0289 0.0269
Onchocerca volvulus 0.0007 0.0024 0.0038
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0236 0.2543
Schistosoma mansoni ferritin 0.0027 0.0424 0.048
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0007 0.0024 0.0075
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0289 0.3106
Schistosoma mansoni nuclear receptor nhr-48 0.0016 0.0191 0.0216
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.1918 0.2923
Echinococcus granulosus snurportin 1 0.0336 0.6834 0.6827
Giardia lamblia NADH oxidase lateral transfer candidate 0.0018 0.0236 0.036
Onchocerca volvulus 0.0025 0.0396 0.4472
Echinococcus multilocularis calpain family protein 1, d 0.0048 0.086 0.0841
Loa Loa (eye worm) hypothetical protein 0.0048 0.086 0.1259
Treponema pallidum bacterioferrin (TpF1) 0.0027 0.0424 0.0615
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0396 0.0573
Echinococcus multilocularis nuclear receptor nhr 48 0.0016 0.0191 0.0171
Brugia malayi photoreceptor-specific nuclear receptor 0.0033 0.0552 0.0841
Echinococcus multilocularis calpain 5 0.002 0.0289 0.0269
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0016 0.0191 0.0171
Plasmodium falciparum thioredoxin reductase 0.0051 0.093 1
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0007 0.002 0.022
Trichomonas vaginalis ferritin, putative 0.0027 0.0424 0.0628
Entamoeba histolytica hypothetical protein 0.0078 0.1476 0.2221
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0217 0.2331
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0349 0.3754
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0007 0.002 0.022
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.2624 0.2972
Entamoeba histolytica protein kinase, putative 0.002 0.0289 0.0409
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0236 0.2543
Loa Loa (eye worm) aldehyde dehydrogenase 0.0007 0.002 0.003
Trypanosoma brucei calpain-like protein, putative 0.002 0.0289 0.3106
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0236 0.2543
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0012 0.0108 0.0158
Echinococcus granulosus calpain 5 0.002 0.0289 0.0269

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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