Detailed information for compound 554559

Basic information

Technical information
  • TDR Targets ID: 554559
  • Name: ((4-Methyl-2-nitrophenyl)azo)-2-naphthol
  • MW: 307.303 | Formula: C17H13N3O3
  • H donors: 1 H acceptors: 3 LogP: 4.39 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(c(c1)[N+](=O)[O-])N/N=C\1/C(=O)C=Cc2c1cccc2
  • InChi: 1S/C17H13N3O3/c1-11-6-8-14(15(10-11)20(22)23)18-19-17-13-5-3-2-4-12(13)7-9-16(17)21/h2-10,18H,1H3/b19-17-
  • InChiKey: ATXLALDFCMZNHY-ZPHPHTNESA-N  


Substructure search Similarity search

Network

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Synonyms

  • (1Z)-1-[(4-methyl-2-nitro-phenyl)hydrazono]naphthalen-2-one
  • (1Z)-1-[(4-methyl-2-nitrophenyl)hydrazono]-2-naphthalenone
  • (1Z)-1-[(4-methyl-2-nitro-phenyl)hydrazinylidene]naphthalen-2-one
  • (1Z)-1-[(4-methyl-2-nitrophenyl)hydrazinylidene]naphthalen-2-one
  • 1-((2-Nitro-4-methylphenyl)azo)-2-naphthol
  • 1-((4-Methyl-2-nitrophenyl)azo)-2-naphthalenol
  • 1-(4-Methyl-2-nitrophenylazo)-2-naphthol
  • 1-(o-Nitro-p-tolylazo)-2-naphthol
  • 1-[(4-methyl-2-nitrophenyl)hydrazinylidene]naphthalen-2-one
  • 1-[(4-methyl-2-nitro-phenyl)hydrazono]naphthalen-2-one
  • 1-[(4-methyl-2-nitrophenyl)hydrazono]-2-naphthalenone
  • 1-[(4-methyl-2-nitro-phenyl)hydrazinylidene]naphthalen-2-one
  • 1-[(E)-(4-methyl-2-nitrophenyl)diazenyl]-2-naphthol
  • 12238-48-1
  • 12240-01-6
  • 12240-02-7
  • 2-Naphthalenol, 1-((4-methyl-2-nitrophenyl)azo)-
  • 2-Naphthalenol, 1-[(4-methyl-2-nitrophenyl)azo]-
  • 2425-85-6
  • 39310-30-0
  • Accosperse Toluidine Red XL
  • ADC Toluidine Red B
  • AI3-30760
  • Atlasol Spirit Red 3
  • Basoflex Red 361
  • C.I. 12120
  • C.I. Pigment Red 3 (8CI)
  • C.I. Pigment Red 3
  • C.I.12120
  • C.I.pigment Red 3
  • C.P. Toluidine Toner A-2989
  • C.P. Toluidine Toner A-2990
  • C.P. Toluidine Toner Dark RS-3340
  • C.P. Toluidine Toner Deep X-1865
  • C.P. Toluidine Toner Light RS-3140
  • C.P. Toluidine Toner RT-6101
  • C.P. Toluidine Toner RT-6104
  • C.P.Toluidine Toner A-2989
  • C.P.Toluidine Toner A-2990
  • C.P.Toluidine Toner Dark RS-3340
  • C.P.Toluidine Toner Deep X-1865
  • C.P.Toluidine Toner Light RS-3140
  • C.P.Toluidine Toner RT-6101
  • C.P.Toluidine Toner RT-6104
  • Calcotone Toluidine Red YP
  • Carnelio Helio Red
  • CCRIS 4013
  • Cerven pigment 3 [Czech]
  • Chromatex Red J
  • CI 12120
  • CI PIGMENT RED 3
  • CP Toluidine toner A-2989
  • D and C Red No. 35
  • Dainichi Permanent Red 4 R
  • Deep Fastona Red
  • Duplex Toluidine Red L 20-3140
  • EINECS 219-372-2
  • Eljon Fast Scarlet PV Extra
  • Eljon Fast Scarlet RN
  • Enialit Light Red RL
  • Fast Red A (VAN)
  • Fast Red A
  • Fast Red A (pigment)
  • Fast Red AB
  • Fast Red J
  • Fast Red JE
  • Fast Red R
  • Fastona Red B
  • Fastona Scarlet RL
  • Fastona Scarlet YS
  • Graphtol Red A-4RL
  • Hansa Red B
  • Hansa Red G
  • Hansa Scarlet RB
  • Hansa Scarlet RN
  • Hansa Scarlet RNC
  • Helio Fast Red BN
  • Helio Fast Red RL
  • Helio Fast Red RN
  • Helio Red RL
  • Helio Red Toner
  • Hispalit Fast Scarlet RN
  • HSDB 4357
  • Independence Red
  • Irgalite Fast Red P4R
  • Irgalite Fast Scarlet RND
  • Irgalite Red PV2
  • Irgalite Red RNPX
  • Irgalite Scarlet RB
  • Isol Fast Red HB
  • Isol Fast Red RN2B
  • Isol Fast Red RN2G
  • Isol Fast Red RNB
  • Isol Fast Red RNG
  • Isol Toluidine Red HB
  • Isol Toluidine Red RN2B
  • Isol Toluidine Red RN2G
  • Isol Toluidine Red RNB
  • Isol Toluidine Red RNG
  • Kromon Helio Fast Red
  • Kromon Helio Fast Red YS
  • Lake Red 4R
  • Lake Red 4RII
  • Lithol Fast Scarlet RN
  • Lutetia Fast Red 3R
  • Lutetia Fast Scarlet RF
  • Lutetia Fast Scarlet RJN
  • Monolite Fast Scarlet CA
  • Monolite Fast Scarlet GSA
  • Monolite Fast Scarlet RB
  • Monolite Fast Scarlet RBA
  • Monolite Fast Scarlet RN
  • Monolite Fast Scarlet RNA
  • Monolite Fast Scarlet RNV
  • Monolite Fast Scarlet RT
  • NCGC00164084-01
  • NCI-C60366
  • No. 2 Forthfast Scarlet
  • NSC 45193
  • NSC45193
  • Oralith Red P4R
  • Permanent Red 4R
  • Pigment Red 3
  • Pigment Red RL
  • Pigment Ruby
  • Pigment Scarlet
  • Pigment Scarlet B
  • Pigment Scarlet N
  • Pigment Scarlet R
  • Pigment Scarlet [Russian]
  • Polymo Red FGN
  • Recolite Fast Red RBL
  • Recolite Fast Red RL
  • Recolite Fast Red RYL
  • Recolite Fast Red BL
  • Sanyo Scarlet Pure
  • Sanyo Scarlet Pure No. 1000
  • Scarlet Pigment RN
  • Segnale Light Red 2B
  • Segnale Light Red B
  • Segnale Light Red BR
  • Segnale Light Red C4R
  • Segnale Light Red RL
  • Siegle Red 1
  • Siegle Red B
  • Siegle Red BB
  • Silogomma Red RLL
  • Silosol Red RBN
  • Silosol Red RN
  • Siloton Red BRLL
  • Siloton Red RLL
  • Symuler Fast Scarlet 4R
  • Syton Fast Scarlet RB
  • Syton Fast Scarlet RD
  • Syton Fast Scarlet RN
  • Tertropigment Red HAB
  • Tertropigment Scarlet LRN
  • toluidine red
  • Toluidine Red 10451
  • Toluidine Red 3B
  • Toluidine Red 4R
  • Toluidine Red BFB
  • Toluidine Red BFGG
  • Toluidine Red D 28-3930
  • Toluidine Red Light
  • Toluidine Red M 20-3785
  • Toluidine Red R
  • Toluidine Red RT-115
  • Toluidine Red Toner
  • Toluidine Red XL 20-3050
  • Toluidine Toner
  • Toluidine Toner Dark 5040
  • Toluidine Toner HR X-2700
  • Toluidine Toner HR X-2741
  • Toluidine Toner Keep HR X-2742
  • Toluidine Toner L20-3300
  • Toluidine Toner RT-252
  • Toluidine Toner L 20-3300
  • Versal Scarlet PRNL
  • Versal Scarlet RNL
  • Vulcafor Scarlet A
  • ZINC03861455
  • [(4-Methyl-2-nitrophenyl)azo]-2-naphthol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0373 0.7227 0.5
Loa Loa (eye worm) hypothetical protein 0.0037 0.0113 0.0594
Schistosoma mansoni hypothetical protein 0.0069 0.0783 1
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0113 0.5
Brugia malayi beta-lactamase family protein 0.0037 0.0113 0.0594
Brugia malayi MH2 domain containing protein 0.0121 0.1893 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0113 0.0594
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.1893 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0113 0.0594
Onchocerca volvulus 0.0037 0.0113 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0113 0.5
Loa Loa (eye worm) hypothetical protein 0.0101 0.1457 0.7695
Plasmodium falciparum enoyl-acyl carrier reductase 0.0373 0.7227 0.5
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0113 0.0113
Onchocerca volvulus 0.0037 0.0113 0.5
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0113 0.0594
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0113 0.1438
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0373 0.7227 0.5
Loa Loa (eye worm) beta-lactamase 0.0037 0.0113 0.0594
Loa Loa (eye worm) hypothetical protein 0.0069 0.0783 0.4133
Loa Loa (eye worm) hypothetical protein 0.0037 0.0113 0.0594
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.1893 1
Leishmania major hypothetical protein, conserved 0.0037 0.0113 0.5
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0373 0.7227 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.1457 0.7695
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0373 0.7227 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0504 1 1
Trichomonas vaginalis hypothetical protein 0.0373 0.7227 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0113 0.0113
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0373 0.7227 1
Brugia malayi beta-lactamase 0.0037 0.0113 0.0594
Loa Loa (eye worm) hypothetical protein 0.0037 0.0113 0.0594
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0113 0.5
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0113 0.1438
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0237 0.4353 0.596
Loa Loa (eye worm) hypothetical protein 0.0037 0.0113 0.0594
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0373 0.7227 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.1457 0.7695
Loa Loa (eye worm) hypothetical protein 0.0037 0.0113 0.0594
Brugia malayi beta-lactamase family protein 0.0037 0.0113 0.0594
Onchocerca volvulus 0.0037 0.0113 0.5
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0373 0.7227 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.1457 0.7695
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0783 0.4133

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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