Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0014 | 0.0194 | 0.1455 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.1168 | 1 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0014 | 0.0194 | 0.0981 |
Echinococcus granulosus | tar DNA binding protein | 0.0126 | 0.51 | 0.7354 |
Onchocerca volvulus | 0.0049 | 0.1718 | 0.3513 | |
Loa Loa (eye worm) | RNA binding protein | 0.0126 | 0.51 | 0.51 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0379 | 0.2074 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0049 | 0.1718 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1734 | 0.25 |
Echinococcus granulosus | Smad4 | 0.0016 | 0.0271 | 0.0392 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0037 | 0.1173 | 0.6772 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0379 | 0.0379 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.1168 | 1 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0014 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0238 | 1 | 1 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.0999 | 0.5745 |
Schistosoma mansoni | Smad4 | 0.0016 | 0.0271 | 0.0392 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0271 | 0.0271 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0014 | 0.0194 | 0.0981 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1003 | 0.1446 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.1085 | 0.6251 |
Echinococcus multilocularis | 0.0011 | 0.0028 | 0.004 | |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.1168 | 0.6741 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1003 | 0.1446 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1173 | 0.1173 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.1003 | 0.1446 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0194 | 0.0981 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.1003 | 0.1446 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1734 | 0.25 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0194 | 0.0194 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0271 | 0.0392 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0014 | 0.0194 | 0.0194 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0194 | 0.0981 |
Onchocerca volvulus | 0.0014 | 0.0194 | 0.0396 | |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.1718 | 1 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0012 | 0.0106 | 0.046 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0379 | 0.2074 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0379 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0126 | 0.51 | 0.51 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0014 | 0.0194 | 0.0981 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0271 | 0.0271 |
Onchocerca volvulus | 0.0014 | 0.0194 | 0.0396 | |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.1003 | 0.1446 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0068 | 0.255 | 0.255 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0271 | 0.0271 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.1168 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.1003 | 0.1003 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0049 | 0.1718 | 1 |
Brugia malayi | cytochrome P450 | 0.0011 | 0.0028 | 0.0028 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.1718 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0016 | 0.0271 | 0.0392 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0014 | 0.0194 | 0.1455 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1173 | 0.1173 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.1085 | 0.6251 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.1085 | 0.6251 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.4119 | 0.4119 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0379 | 0.1887 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0049 | 0.1718 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1734 | 0.25 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1718 | 0.1718 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0016 | 0.0271 | 0.0392 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0379 | 0.1897 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0271 | 0.0392 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0379 | 0.1887 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0037 | 0.1173 | 0.5 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0014 | 0.0194 | 0.1455 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0016 | 0.0271 | 0.0271 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.1718 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0194 | 0.0194 |
Brugia malayi | TAR-binding protein | 0.0126 | 0.51 | 0.51 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0014 | 0.0194 | 0.1455 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0028 | 0.004 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.2676 | 0.386 |
Brugia malayi | Smad1 | 0.0016 | 0.0271 | 0.0271 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0014 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.1734 | 0.1734 |
Echinococcus multilocularis | Smad4 | 0.0016 | 0.0271 | 0.0392 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0194 | 0.1455 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.1718 | 0.1718 |
Echinococcus multilocularis | smad | 0.0016 | 0.0271 | 0.0392 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.4892 | 1 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0194 | 0.0981 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0379 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 | 0.0011 | 0.0028 | 0.0028 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0194 | 0.0194 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.0999 | 0.5745 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.1168 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0049 | 0.1718 | 1 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.1085 | 0.6251 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0194 | 0.1455 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0238 | 1 | 1 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0049 | 0.1718 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0049 | 0.1718 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0379 | 0.0546 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.1003 | 0.1446 |
Onchocerca volvulus | 0.0014 | 0.0194 | 0.0396 | |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0014 | 0.0194 | 0.0981 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0011 | 0.0028 | 0.0028 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0194 | 0.0981 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0104 | 0.4119 | 0.4119 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0379 | 0.3077 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1173 | 0.1173 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0037 | 0.1173 | 1 |
Onchocerca volvulus | 0.0014 | 0.0194 | 0.0396 | |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0028 | 0.0028 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0049 | 0.1718 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.1003 | 0.1003 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0049 | 0.1718 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1003 | 0.1003 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0271 | 0.0271 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0016 | 0.0271 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1718 | 0.1718 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.1003 | 0.1003 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.4892 | 0.4892 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0379 | 0.1897 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1734 | 0.25 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.4892 | 0.4892 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0379 | 0.3077 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0194 | 0.0981 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.2676 | 0.2676 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0014 | 0.0194 | 0.0981 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.4892 | 1 |
Loa Loa (eye worm) | Smad1 | 0.0016 | 0.0271 | 0.0271 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0194 | 0.0194 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0194 | 0.0981 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0011 | 0.0028 | 0.0028 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.1168 | 0.1684 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0014 | 0.0194 | 0.0981 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.1003 | 0.1446 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0016 | 0.0271 | 0.0392 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0014 | 0.0194 | 0.0981 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0014 | 0.0194 | 0.028 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.1168 | 1 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0014 | 0.0194 | 0.0981 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0379 | 0.0546 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0379 | 0.3077 |
Brugia malayi | hypothetical protein | 0.0122 | 0.4892 | 0.4892 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1003 | 0.1446 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0194 | 0.0194 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.1168 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1003 | 0.1446 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0037 | 0.1173 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0014 | 0.0194 | 0.0194 |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0028 | 0.0028 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0194 | 0.0194 |
Echinococcus granulosus | geminin | 0.0168 | 0.6934 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.6934 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.51 | 0.7354 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.51 | 0.7354 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0014 | 0.0194 | 0.1455 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.1168 | 1 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.1168 | 0.6741 |
Brugia malayi | RNA binding protein | 0.0126 | 0.51 | 0.51 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0014 | 0.0194 | 0.028 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.1718 | 1 |
Echinococcus granulosus | smad | 0.0016 | 0.0271 | 0.0392 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.1003 | 0.1446 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.1168 | 0.1684 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.1168 | 0.1684 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.1168 | 0.6387 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0049 | 0.1718 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1173 | 0.1173 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0014 | 0.0194 | 0.0981 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.1168 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.2676 | 0.2676 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.51 | 0.7354 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.1168 | 0.1684 |
Mycobacterium ulcerans | hypothetical protein | 0.0049 | 0.1718 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0194 | 0.0981 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0379 | 0.0546 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0104 | 0.4119 | 0.4119 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1734 | 0.25 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0049 | 0.1718 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0014 | 0.0194 | 0.0194 |
Schistosoma mansoni | smad | 0.0016 | 0.0271 | 0.0392 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0194 | 0.0981 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0014 | 0.0194 | 0.028 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0194 | 0.0981 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0011 | 0.0028 | 0.0028 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.51 | 0.7354 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0037 | 0.1173 | 0.6772 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0379 | 0.3077 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0271 | 0.0392 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1734 | 0.25 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0014 | 0.0194 | 0.0981 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0014 | 0.0194 | 0.0981 |
Brugia malayi | Inositol-1 | 0.0037 | 0.1168 | 0.1168 |
Toxoplasma gondii | propionate-CoA ligase | 0.0014 | 0.0194 | 0.1455 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0194 | 0.1455 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0014 | 0.0194 | 0.0981 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.1718 | 0.1718 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0011 | 0.0028 | 0.004 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0379 | 0.0546 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.1718 | 0.1718 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.1734 | 0.1734 |
Echinococcus multilocularis | geminin | 0.0168 | 0.6934 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.1718 | 1 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0014 | 0.0194 | 0.0981 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1734 | 0.25 |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0028 | 0.0028 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.1718 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0126 | 0.51 | 0.7354 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.51 | 0.7354 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0379 | 0.0379 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0379 | 0.1212 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0379 | 0.2074 |
Schistosoma mansoni | cytochrome P450 | 0.0011 | 0.0028 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1718 | 0.1718 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0126 | 0.51 | 0.51 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0016 | 0.0271 | 0.0392 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.1168 | 0.1168 |
Brugia malayi | Cytochrome P450 family protein | 0.0068 | 0.255 | 0.255 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0049 | 0.1718 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0126 | 0.51 | 0.51 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.6934 | 1 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0016 | 0.0271 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1173 | 0.1173 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0104 | 0.4119 | 0.4119 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.