Detailed information for compound 555322

Basic information

Technical information
  • TDR Targets ID: 555322
  • Name: sodium 2-iodobenzoate
  • MW: 271.008 | Formula: C7H5INaO2
  • H donors: 0 H acceptors: 2 LogP: 2.75 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]C(=O)c1ccccc1I.[NaH+]
  • InChi: 1S/C7H5IO2.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4H,(H,9,10);/q;+1/p-1
  • InChiKey: XBMGRDWEYMVTOS-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

  • 2-iodobenzoic acid
  • 2532-17-4
  • BENZOIC ACID, o-IODO-, SODIUM SALT
  • Sodium o-iodobenzoate
  • o-Iodobenzoic acid sodium salt

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0034 0.0944 0.0924
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.1498 0.1479
Brugia malayi Calcitonin receptor-like protein seb-1 0.0107 0.3474 0.3422
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.1477 0.1409
Loa Loa (eye worm) hypothetical protein 0.0034 0.0944 0.0868
Schistosoma mansoni hypothetical protein 0.0034 0.0944 0.0924
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0294 1 1
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.0294 1 0.5
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0944 0.0871
Loa Loa (eye worm) hypothetical protein 0.0073 0.2303 0.2238
Brugia malayi hypothetical protein 0.024 0.8129 0.8114
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0777 0.0699
Plasmodium falciparum adenosylhomocysteinase 0.0294 1 0.5
Leishmania major S-adenosylhomocysteine hydrolase 0.0294 1 0.5
Schistosoma mansoni cpg binding protein 0.0029 0.0777 0.0757
Schistosoma mansoni survival motor neuron protein 0.0049 0.1477 0.1458
Brugia malayi CXXC zinc finger family protein 0.0029 0.0777 0.0703
Schistosoma mansoni hypothetical protein 0.0049 0.1477 0.1458
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.1498 0.1479
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.2254 0.2237
Echinococcus multilocularis geminin 0.0176 0.5878 0.5869
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0107 0.3474 0.3422
Echinococcus multilocularis adenosylhomocysteinase 0.0294 1 1
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.0294 1 0.5
Onchocerca volvulus Huntingtin homolog 0.0125 0.4102 1
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0294 1 0.5
Schistosoma mansoni hypothetical protein 0.0073 0.2303 0.2286
Schistosoma mansoni adenosylhomocysteinase 0.0182 0.6102 0.6093
Schistosoma mansoni adenosylhomocysteinase 0.0182 0.6102 0.6093
Echinococcus multilocularis cpg binding protein 0.0031 0.0834 0.0814
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0294 1 0.5
Schistosoma mansoni cpg binding protein 0.0031 0.0834 0.0814
Brugia malayi hypothetical protein 0.0125 0.4102 0.4055
Schistosoma mansoni hypothetical protein 0.0071 0.2254 0.2237
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0944 0.0924
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.0294 1 0.5
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.0294 1 0.5
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.1498 0.1479
Loa Loa (eye worm) adenosylhomocysteinase 0.0294 1 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.1498 0.1427
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.1498 0.1479
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.1903 0.1885
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0944 0.0924
Entamoeba histolytica adenosylhomocysteinase, putative 0.0294 1 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.1498 0.1479
Schistosoma mansoni adenosylhomocysteinase 0.0182 0.6102 0.6093
Schistosoma mansoni adenosylhomocysteinase 0.0182 0.6102 0.6093
Echinococcus granulosus geminin 0.0176 0.5878 0.5869
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.0294 1 0.5
Echinococcus granulosus survival motor neuron protein 1 0.024 0.8129 0.8125
Schistosoma mansoni adenosylhomocysteinase 0.0294 1 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0944 0.0868
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0083 0.0061
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.0294 1 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.3474 0.3419
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.1498 0.1479
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.1498 0.1479
Echinococcus multilocularis survival motor neuron protein 1 0.024 0.8129 0.8125
Echinococcus granulosus cpg binding protein 0.0031 0.0834 0.0814
Brugia malayi hypothetical protein 0.0071 0.2254 0.2193
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0092 0.2983 0.2983
Loa Loa (eye worm) hypothetical protein 0.0125 0.4102 0.4053
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0944 0.0871
Loa Loa (eye worm) hypothetical protein 0.0125 0.4102 0.4053
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0107 0.3474 0.3419
Schistosoma mansoni cpg binding protein 0.0031 0.0834 0.0814
Loa Loa (eye worm) hypothetical protein 0.024 0.8129 0.8114
Onchocerca volvulus 0.0049 0.1477 0.2106
Schistosoma mansoni hypothetical protein 0.0034 0.0944 0.0924
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0944 0.0924
Schistosoma mansoni hypothetical protein 0.0176 0.5878 0.5869
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0294 1 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.1498 0.143
Onchocerca volvulus Huntingtin homolog 0.0125 0.4102 1
Echinococcus granulosus adenosylhomocysteinase 0.0294 1 1
Toxoplasma gondii adenosylhomocysteinase, putative 0.0294 1 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.2254 0.2237
Echinococcus multilocularis GPCR, family 2 0.0034 0.0944 0.0924
Schistosoma mansoni hypothetical protein 0.0034 0.0944 0.0924
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.2254 0.2237
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0083 0.0061
Echinococcus granulosus GPCR family 2 0.0034 0.0944 0.0924
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.2303 0.2241
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0944 0.0924
Schistosoma mansoni hypothetical protein 0.0176 0.5878 0.5869

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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