Detailed information for compound 555482

Basic information

Technical information
  • TDR Targets ID: 555482
  • Name: (2S)-2-amino-6-[[(5S)-5-amino-6-hydroxy-6-oxo -hexyl]amino]hexanoic acid
  • MW: 275.345 | Formula: C12H25N3O4
  • H donors: 5 H acceptors: 4 LogP: -5.24 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: N[C@H](C(=O)O)CCCCNCCCC[C@@H](C(=O)O)N
  • InChi: 1S/C12H25N3O4/c13-9(11(16)17)5-1-3-7-15-8-4-2-6-10(14)12(18)19/h9-10,15H,1-8,13-14H2,(H,16,17)(H,18,19)/t9-,10-/m0/s1
  • InChiKey: HYLBTMZBXLEVCL-UWVGGRQHSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-amino-6-[[(5S)-5-amino-6-hydroxy-6-oxohexyl]amino]hexanoic acid
  • (2S)-2-azanyl-6-[[(5S)-5-azanyl-6-hydroxy-6-oxo-hexyl]amino]hexanoic acid
  • (2S)-2-amino-6-[[(5S)-5-amino-6-hydroxy-6-keto-hexyl]amino]hexanoic acid
  • lysinenorleucine
  • 25612-46-8
  • Lysylnorleucine
  • L-Lysine, N6-(5-amino-5-carboxypentyl)-, (S)-
  • Lys-nle

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0041 0.035 0.0825
Loa Loa (eye worm) hypothetical protein 0.0069 0.071 0.0908
Brugia malayi intermediate filament protein 0.0029 0.0197 0.0252
Onchocerca volvulus 0.0029 0.0197 0.0748
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0447 0.0635
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0044 0.0396 0.0531
Echinococcus granulosus lysine specific demethylase 5A 0.0099 0.1103 0.122
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.065 0.0831
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0331 0.0408
Echinococcus multilocularis dnaJ subfamily B 0.0398 0.4957 0.4955
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0029 0.0198 0.0194
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0019 0.0016
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0299 0.0382
Loa Loa (eye worm) DnaJ domain-containing protein 0.0062 0.0626 0.08
Entamoeba histolytica hypothetical protein 0.0038 0.0318 0.0625
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0224 0.022
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0041 0.035 0.0346
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0381 0.0376
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.0167 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0281 0.3446 0.6296
Loa Loa (eye worm) inositol-1 0.0039 0.0331 0.0423
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0324 0.4001 1
Brugia malayi hypothetical protein 0.0025 0.0141 0.0181
Plasmodium vivax DNA repair protein REV1, putative 0.0085 0.0923 0.6261
Loa Loa (eye worm) glutaminase 0.0557 0.7007 0.8962
Loa Loa (eye worm) glutathione reductase 0.0128 0.1472 0.1883
Echinococcus granulosus phd:f box containing protein 0.0026 0.0154 0.0166
Trypanosoma brucei unspecified product 0.0189 0.2264 0.4063
Echinococcus multilocularis dna polymerase eta 0.0433 0.5406 0.5404
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0067 0.0069
Entamoeba histolytica hypothetical protein 0.0025 0.0144 0.0091
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0396 0.0531
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.2085 0.2973
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.3269 0.4664
Plasmodium falciparum DNA repair protein REV1, putative 0.0085 0.0923 0.6261
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0078
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0661 0.0657
Echinococcus granulosus microtubule associated protein 2 0.0712 0.9008 1
Trypanosoma brucei DNA polymerase IV, putative 0.03 0.37 0.6776
Brugia malayi jmjC domain containing protein 0.0026 0.0154 0.0197
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0026 0.0154 0.0137
Echinococcus granulosus lamin dm0 0.0029 0.0197 0.0214
Giardia lamblia PHD finger protein 15 0.0031 0.0224 0.0329
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0141 0.094
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0219 0.0197
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0115 0.076
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0299 0.0348
Mycobacterium tuberculosis Conserved hypothetical protein 0.0274 0.3362 0.8333
Loa Loa (eye worm) hypothetical protein 0.0041 0.035 0.0448
Schistosoma mansoni DNA polymerase eta 0.0433 0.5406 0.5982
Loa Loa (eye worm) hypothetical protein 0.0031 0.0224 0.0287
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0607 0.0776
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.1034 0.1029
Echinococcus multilocularis MAM 0.0018 0.0061 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0085 0.0923 0.1527
Plasmodium falciparum glutathione reductase 0.0128 0.1472 1
Schistosoma mansoni intermediate filament proteins 0.0029 0.0197 0.017
Echinococcus multilocularis dna polymerase kappa 0.03 0.37 0.3697
Mycobacterium tuberculosis Probable reductase 0.0291 0.3582 0.8906
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0219 0.0365
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0267 0.3269 0.4181
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0299 0.0552
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0044 0.0396 0.0531
Brugia malayi jmjC domain containing protein 0.0026 0.0154 0.0197
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0049 0.0459 0.1207
Echinococcus multilocularis phd:f box containing protein 0.0026 0.0154 0.0149
Echinococcus multilocularis L aminoadipate semialdehyde 0.0175 0.2079 0.2076
Schistosoma mansoni inositol monophosphatase 0.0039 0.0331 0.0319
Loa Loa (eye worm) hypothetical protein 0.0231 0.2798 0.3578
Loa Loa (eye worm) RNA binding protein 0.0065 0.0661 0.0845
Loa Loa (eye worm) thioredoxin reductase 0.0128 0.1472 0.1883
Brugia malayi RNA binding protein 0.0065 0.0661 0.0845
Echinococcus multilocularis peregrin 0.0031 0.0224 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.2348 0.4221
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.2085 0.2973
Trypanosoma brucei DNA polymerase IV, putative 0.03 0.37 0.6776
Schistosoma mansoni jumonji domain containing protein 0.0026 0.0154 0.0122
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.1082 0.2978
Trypanosoma brucei DNA polymerase kappa, putative 0.03 0.37 0.6776
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0067 0.0085
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0044 0.0396 0.2672
Schistosoma mansoni terminal deoxycytidyl transferase 0.0274 0.3362 0.3701
Echinococcus multilocularis jumonji domain containing 1A 0.0026 0.0154 0.0149
Echinococcus multilocularis JmjC domain containing protein 4 0.0026 0.0154 0.0149
Echinococcus granulosus L aminoadipate semialdehyde 0.0175 0.2079 0.2305
Brugia malayi glutaminase DH11.1 0.0557 0.7007 0.8962
Trypanosoma brucei DNA polymerase kappa, putative 0.03 0.37 0.6776
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0044 0.0396 0.0531
Echinococcus multilocularis lamin dm0 0.0029 0.0197 0.0193
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0044 0.0396 0.2672
Echinococcus multilocularis cpg binding protein 0.0064 0.0652 0.0647
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0224 0.02
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0459 0.0651
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0661 0.0688
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0291 0.3582 0.8874
Trichomonas vaginalis DNA polymerase eta, putative 0.03 0.37 0.5279
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0278 0.0288
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0033 0.0244 0.0312
Trypanosoma cruzi hypothetical protein, conserved 0.0231 0.2799 0.5072
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0274 0.3362 0.3359
Toxoplasma gondii thioredoxin reductase 0.0128 0.1472 0.4759
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1034 0.1103
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0044 0.0396 0.0985
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0396 0.0531
Echinococcus granulosus sodium:glucose cotransporter 2 0.0041 0.035 0.0384
Echinococcus multilocularis lysine specific demethylase 5A 0.0096 0.1059 0.1055
Plasmodium vivax JmjC domain containing protein 0.0026 0.0154 0.1027
Schistosoma mansoni phd/f-box containing protein 0.0026 0.0154 0.0122
Schistosoma mansoni inositol transporter 0.0041 0.035 0.0341
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0115 0.076
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0144 0.0203
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0085 0.0923 0.2833
Loa Loa (eye worm) jmjC domain-containing protein 0.0099 0.1103 0.1411
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.1103 0.1181
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0331 0.0408
Leishmania major DNA polymerase eta, putative 0.0244 0.2966 0.539
Loa Loa (eye worm) hypothetical protein 0.062 0.7819 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0299 0.2013
Brugia malayi jmjC domain containing protein 0.016 0.1884 0.2409
Trypanosoma cruzi trypanothione reductase, putative 0.0128 0.1472 0.2565
Brugia malayi Muscle positioning protein 4 0.0017 0.0045 0.0057
Brugia malayi jmjC domain containing protein 0.0026 0.0154 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.03 0.37 0.6776
Plasmodium falciparum glutathione reductase 0.0044 0.0396 0.2672
Onchocerca volvulus Alhambra homolog 0.0031 0.0224 0.088
Echinococcus granulosus JmjC domain containing protein 4 0.0026 0.0154 0.0166
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0661 0.0688
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0041 0.035 0.0346
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0299 0.0294
Giardia lamblia DNA damage repair protein 0.0085 0.0923 0.2425
Leishmania major DNA polymerase eta, putative 0.0433 0.5406 1
Echinococcus multilocularis muscleblind protein 0.062 0.7819 0.7818
Trichomonas vaginalis glutaminase, putative 0.0557 0.7007 1
Schistosoma mansoni DNA polymerase IV / kappa 0.0085 0.0923 0.098
Echinococcus multilocularis serotonin receptor 0.0099 0.11 0.1096
Trypanosoma cruzi DNA polymerase kappa, putative 0.03 0.37 0.6776
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0291 0.3582 0.8906
Loa Loa (eye worm) hypothetical protein 0.0099 0.11 0.1407
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0044 0.0396 0.6044
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0459 0.3104
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.2348 0.4221
Trypanosoma brucei DNA polymerase kappa, putative 0.03 0.37 0.6776
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0299 0.0424
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0026 0.0154 0.0074
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0433 0.5406 0.6914
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.1082 0.1384
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0044 0.0396 0.0531
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0044 0.0396 0.0506
Echinococcus granulosus dna polymerase kappa 0.03 0.37 0.4105
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0197 0.0252
Echinococcus granulosus tar DNA binding protein 0.0065 0.0661 0.0729
Trypanosoma brucei DNA polymerase kappa, putative 0.03 0.37 0.6776
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0049 0.0459 0.0426
Schistosoma mansoni lamin 0.0029 0.0197 0.017
Schistosoma mansoni ap endonuclease 0.0037 0.0299 0.0284
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.3269 0.4664
Echinococcus multilocularis solute carrier family 5 0.0041 0.035 0.0346
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0299 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.0111 0.1261 0.2166
Toxoplasma gondii exonuclease III APE 0.0037 0.0299 0.0645
Trypanosoma brucei unspecified product 0.0189 0.2264 0.4063
Trichomonas vaginalis protein kinase inhibitor, putative 0.0062 0.0626 0.089
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0331 0.0326
Echinococcus granulosus dnaJ subfamily B 0.0398 0.4957 0.5501
Leishmania major DNA damage repair protein, putative 0.0085 0.0923 0.1527
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0197
Schistosoma mansoni hypothetical protein 0.0326 0.403 0.4447
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.1034 0.1322
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0299 0.0567
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.1034 0.1029
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0044 0.0396 0.0531
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0044 0.0396 0.0531
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0144 0.0203
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.1082 0.1828
Brugia malayi hypothetical protein 0.0038 0.0318 0.0406
Entamoeba histolytica hypothetical protein 0.0049 0.0459 0.106
Schistosoma mansoni ran 0.0022 0.0115 0.0078
Brugia malayi hypothetical protein 0.0016 0.0029 0.0037
Giardia lamblia NADH oxidase lateral transfer candidate 0.0044 0.0396 0.0843
Schistosoma mansoni inositol monophosphatase 0.0039 0.0331 0.0319
Echinococcus multilocularis serotonin receptor 0.0099 0.11 0.1096
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0324 0.4001 1
Giardia lamblia Kinase, PLK 0.0097 0.1082 0.2903
Schistosoma mansoni cpg binding protein 0.0064 0.0652 0.0677
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0331 0.0469
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0324 0.4001 1
Echinococcus granulosus dnaJ subfamily C 6 0.0062 0.0626 0.069
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0024 0.0031
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0299 0.0424
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0299 0.0348
Brugia malayi Sodium:solute symporter family protein 0.0041 0.035 0.0448
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.2085 0.2973
Plasmodium falciparum importin beta, putative 0.0031 0.0219 0.1468
Echinococcus granulosus geminin 0.018 0.2147 0.2379
Echinococcus multilocularis citrate lyase subunit beta protein 0.0027 0.0167 0.0163
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0331 0.0408
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.2085 0.2973
Mycobacterium ulcerans DNA polymerase IV 0.03 0.37 0.5165
Schistosoma mansoni cpg binding protein 0.0064 0.0652 0.0677
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0318 0.0313
Loa Loa (eye worm) hypothetical protein 0.0025 0.0141 0.0181
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0299 0.0382
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0381 0.0418
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0044 0.0396 0.2672
Leishmania major hypothetical protein, conserved 0.0231 0.2799 0.5072
Schistosoma mansoni hypothetical protein 0.0062 0.0626 0.0648
Giardia lamblia DINP protein human, muc B family 0.0281 0.3446 1
Echinococcus granulosus sodium:myo inositol cotransporter 0.0041 0.035 0.0384
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.3269 0.4664
Entamoeba histolytica hypothetical protein 0.0038 0.0318 0.0625
Trypanosoma brucei DNA polymerase IV, putative 0.0294 0.3616 0.6618
Trypanosoma cruzi DNA damage repair protein, putative 0.0085 0.0923 0.1527
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.015 0.0117
Brugia malayi Thioredoxin reductase 0.0128 0.1472 0.1883
Echinococcus multilocularis thioredoxin glutathione reductase 0.0129 0.1486 0.1482
Brugia malayi Bromodomain containing protein 0.0031 0.0224 0.0287
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0049 0.0459 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0026 0.0154 0.0074
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0175 0.2079 0.227
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.1307 0.418
Trypanosoma brucei DNA damage repair protein, putative 0.0085 0.0923 0.1527
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0299 0.0327
Brugia malayi Importin beta-1 subunit 0.0031 0.0219 0.028
Echinococcus multilocularis dnaJ subfamily C 6 0.0062 0.0626 0.0621
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0331 0.0239
Trypanosoma cruzi hypothetical protein, conserved 0.0085 0.0923 0.1527
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0141 0.005
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0044 0.0396 0.0531
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0299 0.0348
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0175 0.2079 0.266
Trypanosoma cruzi DNA polymerase kappa, putative 0.03 0.37 0.6776
Schistosoma mansoni ap endonuclease 0.0037 0.0299 0.0284
Trypanosoma brucei DNA polymerase kappa, putative 0.03 0.37 0.6776
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0661 0.0688
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0396 0.0531
Schistosoma mansoni hypothetical protein 0.0398 0.4957 0.5481
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0299 0.2013
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.1082 0.1828
Entamoeba histolytica hypothetical protein 0.0038 0.0318 0.0625
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0281 0.3446 0.6296
Echinococcus granulosus muscleblind protein 0.062 0.7819 0.868
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1034 0.1103
Echinococcus granulosus citrate lyase subunit beta protein 0.0027 0.0167 0.0181
Trypanosoma brucei hypothetical protein, conserved 0.0085 0.0923 0.1527
Trypanosoma brucei DNA polymerase kappa, putative 0.03 0.37 0.6776
Schistosoma mansoni hypothetical protein 0.0031 0.0224 0.02
Brugia malayi SEA domain containing protein 0.0017 0.0045 0.0057
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.1103 0.1181
Onchocerca volvulus 0.0029 0.0197 0.0748
Schistosoma mansoni hypothetical protein 0.0038 0.0318 0.0305
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0459 0.3104
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.3269 0.4664
Echinococcus granulosus biogenic amine 5HT receptor 0.0099 0.11 0.1217
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0044 0.0396 0.2672
Mycobacterium ulcerans DNA polymerase IV 0.03 0.37 0.5165
Trypanosoma brucei DNA polymerase kappa, putative 0.0111 0.1261 0.2166
Trypanosoma brucei chrX additional, unordered contigs 0.0085 0.0923 0.1527
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0318 0.0348
Plasmodium falciparum phd finger protein, putative 0.0031 0.0224 0.1506
Trypanosoma brucei DNA polymerase eta, putative 0.0433 0.5406 1
Echinococcus multilocularis muscleblind protein 1 0.062 0.7819 0.7818
Onchocerca volvulus 0.0018 0.0061 0.0081
Echinococcus granulosus lysine specific demethylase 6a 0.0026 0.0154 0.0166
Echinococcus granulosus MAM 0.0018 0.0061 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.03 0.37 0.6776
Trichomonas vaginalis ran, putative 0.0022 0.0115 0.0161
Plasmodium falciparum thioredoxin reductase 0.0044 0.0396 0.2672
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0244 0.2966 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0197 0.0252
Leishmania major hypothetical protein, conserved 0.0026 0.0154 0.0074
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0044 0.0396 0.0434
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0197 0.0252
Mycobacterium ulcerans hypothetical protein 0.0085 0.0923 0.1104
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.1082 0.1157
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0128 0.1472 0.3403
Schistosoma mansoni glutaminase 0.0557 0.7007 0.7768
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.1082 0.1541
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0231 0.2798 0.3072
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0141 0.0092
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0224 0.0384
Schistosoma mansoni cpg binding protein 0.0061 0.0607 0.0627
Schistosoma mansoni hypothetical protein 0.0018 0.0061 0.0019
Brugia malayi glutathione reductase 0.0128 0.1472 0.1883
Echinococcus granulosus importin subunit beta 1 0.0031 0.0219 0.0238
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0141 0.094
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0019 0.0016
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0115 0.0147
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.1082 0.1541
Brugia malayi Inositol-1 0.0039 0.0331 0.0423
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0291 0.3582 0.8906
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0049 0.0459 0.0761
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0224 0.0287
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.1082 0.1541
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0044 0.0396 0.0334
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0115 0.0147
Brugia malayi ImpB/MucB/SamB family protein 0.0274 0.3362 0.43
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0024 0.0031
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0219 0.0214
Leishmania major trypanothione reductase 0.0128 0.1472 0.2565
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.1082 0.5084
Schistosoma mansoni hypothetical protein 0.0018 0.0061 0.0019
Schistosoma mansoni phosphatidylserine receptor 0.0026 0.0154 0.0122
Trypanosoma brucei DNA damage repair protein, putative 0.0085 0.0923 0.1527
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0049 0.0459 0.1207
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0331 0.0408
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0019 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.3269 0.4664
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.2348 0.4221
Loa Loa (eye worm) hypothetical protein 0.0111 0.1261 0.1612
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.0167 0.0099
Echinococcus granulosus snurportin 1 0.0326 0.403 0.4471
Loa Loa (eye worm) hypothetical protein 0.0028 0.019 0.0244
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0661 0.0845
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0057
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0231 0.2798 0.3578
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0044 0.0396 0.0334
Plasmodium vivax importin-beta 2, putative 0.0031 0.0219 0.1468
Plasmodium vivax glutathione reductase, putative 0.0128 0.1472 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.03 0.37 0.5279
Mycobacterium leprae conserved hypothetical protein 0.0049 0.0459 0.0486
Brugia malayi DnaJ domain containing protein 0.0062 0.0626 0.08
Brugia malayi PHD-finger family protein 0.0031 0.0224 0.0287
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.3269 0.4664
Schistosoma mansoni inositol transporter 0.0041 0.035 0.0341
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0661 0.0845
Loa Loa (eye worm) hypothetical protein 0.062 0.7819 1
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0027 0.0167 0.0236
Plasmodium falciparum JmjC domain-containing protein, putative 0.0026 0.0154 0.1027
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0224 0.0384
Trypanosoma cruzi DNA polymerase kappa, putative 0.03 0.37 0.6776
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0291 0.3582 0.8906
Loa Loa (eye worm) hypothetical protein 0.0231 0.2798 0.3578
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0044 0.0396 0.0531
Treponema pallidum NADH oxidase 0.0044 0.0396 0.6044
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0267 0.3269 0.4181
Schistosoma mansoni protein phosphatase 2C 0.0026 0.0154 0.0122
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0044 0.0396 0.0531
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0144 0.0203
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0331 0.0469
Trypanosoma cruzi DNA polymerase kappa, putative 0.03 0.37 0.6776
Toxoplasma gondii NADPH-glutathione reductase 0.0044 0.0396 0.0985
Echinococcus multilocularis musashi 0.0029 0.0197 0.0193
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.2085 0.2973
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0224 0.1506
Echinococcus granulosus high affinity choline transporter 1 0.0369 0.4587 0.509
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0033 0.0244 0.0312
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0331 0.2004
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.016 0.1884 0.188
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.2085 0.2973
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0299 0.0343
Schistosoma mansoni high-affinity choline transporter 0.0369 0.4587 0.5068
Onchocerca volvulus 0.0041 0.035 0.1497
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0274 0.3362 0.3729
Trichomonas vaginalis glutathione reductase, putative 0.0044 0.0396 0.0562
Trypanosoma brucei unspecified product 0.0294 0.3616 0.6618
Entamoeba histolytica deoxycytidyl transferase, putative 0.0274 0.3362 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0396 0.0531
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.016 0.1884 0.2087
Trypanosoma cruzi trypanothione reductase, putative 0.0044 0.0396 0.0531
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0299 0.0348
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0274 0.3362 0.43
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0318 0.0305
Schistosoma mansoni hypothetical protein 0.018 0.2147 0.2345
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0661 0.0688
Onchocerca volvulus 0.0061 0.0607 0.2756
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.0167 0.0099
Mycobacterium tuberculosis Probable oxidoreductase 0.0324 0.4001 1
Echinococcus multilocularis snurportin 1 0.0326 0.403 0.4027
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.2085 0.2973
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0331 0.0362
Brugia malayi Protein kinase domain containing protein 0.0018 0.0061 0.0078
Schistosoma mansoni jumonji domain containing protein 0.0139 0.1615 0.1752
Schistosoma mansoni microtubule-associated protein tau 0.0712 0.9008 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.1082 0.1828
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0078
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.1082 0.1384
Mycobacterium tuberculosis Probable dehydrogenase 0.0291 0.3582 0.8906
Brugia malayi hypothetical protein 0.0018 0.0061 0.0078
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.1082 0.1078
Echinococcus granulosus peregrin 0.0031 0.0224 0.0244
Echinococcus granulosus jumonji domain containing 1A 0.0026 0.0154 0.0166
Trypanosoma cruzi hypothetical protein, conserved 0.0231 0.2799 0.5072
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0141 0.005
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0194 0.0249
Echinococcus granulosus intermediate filament protein 0.0029 0.0197 0.0214
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.1082 0.1197
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.1082 0.1541
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.1082 0.1541
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0044 0.0396 0.0391
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.1034 0.1143
Trypanosoma brucei DNA polymerase kappa, putative 0.03 0.37 0.6776
Trypanosoma cruzi DNA damage repair protein, putative 0.0085 0.0923 0.1527
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0281 0.3446 0.8552
Brugia malayi Muscleblind-like protein 0.062 0.7819 1
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0661 0.0688
Trypanosoma brucei trypanothione reductase 0.0128 0.1472 0.2565
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0092 0.1007 0.3127
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1034 0.1103
Loa Loa (eye worm) hypothetical protein 0.0029 0.0197 0.0252
Echinococcus granulosus sodium:glucose cotransporter 0.0041 0.035 0.0384
Mycobacterium ulcerans glutaminase 0.0557 0.7007 1
Schistosoma mansoni sodium/solute symporter 0.0041 0.035 0.0341
Echinococcus multilocularis high affinity choline transporter 1 0.0369 0.4587 0.4585
Leishmania major importin beta-1 subunit, putative 0.0025 0.0144 0.0056
Loa Loa (eye worm) glutaminase 2 0.0557 0.7007 0.8962
Loa Loa (eye worm) hypothetical protein 0.0099 0.11 0.1407
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0274 0.3362 0.3701
Leishmania major DNA polymerase kappa, putative 0.0085 0.0923 0.1527
Onchocerca volvulus 0.0018 0.0061 0.0081
Echinococcus granulosus lamin 0.0029 0.0197 0.0214
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0057
Brugia malayi ImpB/MucB/SamB family protein 0.0433 0.5406 0.6914
Brugia malayi jmjC domain containing protein 0.0099 0.1103 0.1411
Echinococcus granulosus cpg binding protein 0.0064 0.0652 0.0719
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0026 0.0154 0.0074
Schistosoma mansoni biogenic amine (5HT) receptor 0.0099 0.11 0.1178
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0026 0.0154 0.0137
Brugia malayi polk-prov protein 0.0111 0.1261 0.1612
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0396 0.0531
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0044 0.0396 0.0392
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.0154 0.0197
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.0154 0.0197
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0141 0.094
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0331 0.0666
Trypanosoma brucei hypothetical protein, conserved 0.0231 0.2799 0.5072
Echinococcus multilocularis geminin 0.018 0.2147 0.2143
Trypanosoma cruzi DNA polymerase eta, putative 0.0244 0.2966 0.539
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0044 0.0396 0.0595
Entamoeba histolytica hypothetical protein 0.0038 0.0318 0.0625
Brugia malayi CXXC zinc finger family protein 0.0061 0.0607 0.0776
Brugia malayi TAR-binding protein 0.0065 0.0661 0.0845
Brugia malayi RNA, U transporter 1 0.0087 0.0945 0.1209
Echinococcus granulosus dna polymerase eta 0.0433 0.5406 0.5999
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0029 0.0198 0.0215
Schistosoma mansoni lamin 0.0029 0.0197 0.017
Echinococcus multilocularis lysine specific demethylase 6a 0.0026 0.0154 0.0149
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0115 0.011
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0044 0.0396 0.0531
Loa Loa (eye worm) hypothetical protein 0.0369 0.4587 0.5867
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0129 0.1484 0.1606
Loa Loa (eye worm) hypothetical protein 0.0026 0.0154 0.0197
Schistosoma mansoni ran 0.0022 0.0115 0.0078
Onchocerca volvulus 0.0175 0.2079 0.9974
Loa Loa (eye worm) DOMON domain-containing protein 0.0017 0.0045 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.2206 0.3147
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0331 0.0469
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0049 0.0459 0.0426
Trypanosoma cruzi DNA polymerase eta, putative 0.0433 0.5406 1
Echinococcus multilocularis lamin 0.0029 0.0197 0.0193
Loa Loa (eye worm) hypothetical protein 0.0031 0.0219 0.028
Schistosoma mansoni kinase 0.005 0.0464 0.0467
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0331 0.0758
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0049 0.0459 1
Echinococcus multilocularis microtubule associated protein 2 0.0712 0.9008 0.9007
Trypanosoma brucei hypothetical protein, conserved 0.0085 0.0923 0.1527
Loa Loa (eye worm) hypothetical protein 0.0175 0.2079 0.266
Trichomonas vaginalis mercuric reductase, putative 0.0044 0.0396 0.0562
Leishmania major phosphopantetheinyl transferase-like protein 0.0049 0.0459 0.0651
Leishmania major hypothetical protein, conserved 0.0025 0.0141 0.005
Plasmodium falciparum thioredoxin reductase 0.0128 0.1472 1
Loa Loa (eye worm) TK/ALK protein kinase 0.0018 0.0061 0.0078
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0044 0.0396 0.0334
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0144 0.0056
Echinococcus granulosus thioredoxin glutathione reductase 0.0129 0.1486 0.1645
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0041 0.035 0.0384
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.2206 0.3147
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.1034 0.1143
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0326 0.403 0.5154
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0115 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.1082 0.1541
Onchocerca volvulus Glucosylceramidase homolog 0.0175 0.2085 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0078
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0447 0.0635
Schistosoma mansoni importin beta-1 0.0031 0.0219 0.0194
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.1034 0.1322
Brugia malayi GH02984p 0.0369 0.4587 0.5867
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0141 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.1082 0.1541
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0661 0.0845
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0396 0.0531
Echinococcus granulosus solute carrier family 5 0.0041 0.035 0.0384
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0019 0.0015
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0219 0.0197
Leishmania major DNA polymerase kappa, putative 0.0281 0.3446 0.6296
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0044 0.0396 0.6044
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0291 0.3582 0.8906
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0224 0.0244
Plasmodium vivax thioredoxin reductase, putative 0.0128 0.1472 1
Trypanosoma brucei polo-like protein kinase 0.0097 0.1082 0.1828
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0041 0.035 0.0346
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.0154 0.0197
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0026 0.0154 0.0122
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0049 0.0459 1
Brugia malayi jmjC domain containing protein 0.0026 0.0154 0.0197
Schistosoma mansoni hypothetical protein 0.018 0.2147 0.2345

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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