Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | chromobox protein | 0.0076 | 0.1765 | 0.2347 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.014 | 0.4265 | 0.5 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0223 | 0.752 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0076 | 0.1765 | 0.2347 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0223 | 0.752 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0076 | 0.1765 | 0.2347 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0286 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0286 | 1 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0255 | 0.0339 |
Schistosoma mansoni | chromobox protein | 0.0076 | 0.1765 | 0.2347 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0286 | 1 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0038 | 0.0255 | 0.0339 |
Echinococcus granulosus | jumonji domain containing protein | 0.0043 | 0.0475 | 0.0632 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0286 | 1 | 1 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0043 | 0.0475 | 0.0632 |
Plasmodium falciparum | phd finger protein, putative | 0.0031 | 0 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0101 | 0.2759 | 0.9847 |
Trichomonas vaginalis | chromobox protein, putative | 0.0046 | 0.0583 | 0.0133 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0 | 0.5 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0286 | 1 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0286 | 1 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0286 | 1 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0286 | 1 | 0.5 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0046 | 0.0583 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0286 | 1 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0255 | 0.0339 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0286 | 1 | 1 |
Onchocerca volvulus | 0.0033 | 0.0096 | 0.1642 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0456 | 0.0607 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0223 | 0.752 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0076 | 0.1765 | 0.2347 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0064 | 0.1291 | 0.1717 |
Brugia malayi | Heterochromatin protein 1 | 0.0076 | 0.1765 | 0.6298 |
Echinococcus granulosus | chromobox protein 1 | 0.0076 | 0.1765 | 0.2347 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0038 | 0.0255 | 0.0339 |
Schistosoma mansoni | jumonji domain containing protein | 0.0081 | 0.1943 | 0.2584 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0101 | 0.2759 | 0.3669 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.014 | 0.4265 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0866 | 0.1152 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0096 | 0.0127 |
Brugia malayi | hypothetical protein | 0.0103 | 0.2802 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0076 | 0.1765 | 0.2347 |
Trichomonas vaginalis | chromobox protein, putative | 0.0076 | 0.1765 | 0.1371 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.014 | 0.4265 | 0.5 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0038 | 0.0255 | 0.0339 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0286 | 1 | 1 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.0223 | 0.752 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0076 | 0.1765 | 0.1371 |
Brugia malayi | chromobox protein homolog 3 | 0.0043 | 0.0456 | 0.1629 |
Trichomonas vaginalis | chromobox protein, putative | 0.0046 | 0.0583 | 0.0133 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.0456 | 0.7826 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.0255 | 0.0911 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0101 | 0.2759 | 0.3669 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.