Detailed information for compound 555963

Basic information

Technical information
  • TDR Targets ID: 555963
  • Name: benzene-1,4-diol; formaldehyde
  • MW: 140.137 | Formula: C7H8O3
  • H donors: 2 H acceptors: 3 LogP: 2.45 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(cc1)O.C=O
  • InChi: 1S/C6H6O2.CH2O/c7-5-1-2-6(8)4-3-5;1-2/h1-4,7-8H;1H2
  • InChiKey: UREVLELSVZQJTM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • benzene-1,4-diol; methanal
  • formaldehyde; hydroquinone
  • formaldehyde-hydroquinone polymer
  • 126858-74-0
  • 26353-95-7
  • Hydroquinone-formaldehyde polymer
  • FA-HQ
  • Formaldehyde, polymer with 1,4-benzenediol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0018 0.034 0.0268
Echinococcus granulosus sex peptide receptor 0.0018 0.034 0.0268
Brugia malayi Dopamine receptor 0.0018 0.034 0.0301
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus multilocularis dnaJ subfamily B 0.0422 1 1
Echinococcus granulosus g protein coupled receptor 0.0018 0.034 0.0268
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0018 0.034 0.0301
Echinococcus granulosus neuropeptide receptor 0.0018 0.034 0.0268
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0037 0.0787 0.0894
Echinococcus granulosus g-protein coupled receptor 0.0018 0.034 0.0268
Echinococcus granulosus tar DNA binding protein 0.0065 0.1463 0.1399
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0018 0.034 0.034
Schistosoma mansoni amine GPCR 0.0018 0.034 0.034
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0018 0.034 0.034
Brugia malayi G protein-coupled receptor F59B2.13 0.0018 0.034 0.0301
Echinococcus multilocularis sex peptide receptor 0.0018 0.034 0.0268
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.034 0.0268
Schistosoma mansoni biogenic amine receptor 0.0018 0.034 0.034
Schistosoma mansoni neuropeptide receptor 0.0018 0.034 0.034
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0074 0.0074
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.034 0.0268
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.034 0.0268
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0018 0.034 0.0301
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0018 0.034 0.034
Schistosoma mansoni hypothetical protein 0.0175 0.4083 0.4083
Brugia malayi sulfakinin receptor protein 0.0018 0.034 0.0301
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0018 0.034 0.0297
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0787 0.0787
Brugia malayi neuropeptide F receptor 0.0018 0.034 0.0301
Schistosoma mansoni opsin-like receptor 0.0018 0.034 0.034
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0787 0.0787
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Schistosoma mansoni hypothetical protein 0.0018 0.034 0.034
Loa Loa (eye worm) TYRA-2 protein 0.0018 0.034 0.0297
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.034 0.034
Echinococcus multilocularis tar DNA binding protein 0.0065 0.1463 0.1399
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.034 0.034
Schistosoma mansoni hypothetical protein 0.0018 0.034 0.034
Brugia malayi beta-lactamase family protein 0.0037 0.0787 0.0898
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.034 0.0268
Echinococcus granulosus neuropeptide receptor 0.0018 0.034 0.0268
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus multilocularis geminin 0.0175 0.4083 0.4039
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0018 0.034 0.034
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Brugia malayi hypothetical protein 0.0018 0.034 0.0301
Echinococcus multilocularis fmrfamide receptor 0.0018 0.034 0.0268
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0237 0.5579 0.7027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.034 0.034
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.034 0.0268
Schistosoma mansoni biogenic amine receptor 0.0018 0.034 0.034
Schistosoma mansoni hypothetical protein 0.0018 0.034 0.034
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Schistosoma mansoni cpg binding protein 0.0031 0.0648 0.0648
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Schistosoma mansoni tar DNA-binding protein 0.0065 0.1463 0.1463
Loa Loa (eye worm) hypothetical protein 0.0037 0.0787 0.0894
Echinococcus granulosus cpg binding protein 0.0031 0.0648 0.0578
Echinococcus granulosus orexin receptor type 2 0.0018 0.034 0.0268
Echinococcus granulosus hypothetical protein 0.0018 0.034 0.0268
Schistosoma mansoni amine GPCR 0.0018 0.034 0.034
Echinococcus granulosus neuropeptide s receptor 0.0018 0.034 0.0268
Brugia malayi larval opioid receptor 0.0018 0.034 0.0301
Echinococcus granulosus tachykinin peptides receptor 99D 0.0018 0.034 0.0268
Brugia malayi GnHR receptor homolog 0.0018 0.034 0.0301
Loa Loa (eye worm) hypothetical protein 0.0037 0.0787 0.0894
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0322 0.7607 1
Echinococcus multilocularis neuropeptide receptor 0.0018 0.034 0.0268
Brugia malayi ORL1-like opioid receptor 0.0018 0.034 0.0301
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0018 0.034 0.0297
Echinococcus granulosus 7TM GPCR rhodopsin 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.034 0.0268
Brugia malayi beta-lactamase family protein 0.0037 0.0787 0.0898
Schistosoma mansoni tar DNA-binding protein 0.0065 0.1463 0.1463
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.034 0.034
Schistosoma mansoni amine GPCR 0.0018 0.034 0.034
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0018 0.034 0.034
Brugia malayi Dopamine receptor protein 1 0.0018 0.034 0.0301
Echinococcus multilocularis thymidylate synthase 0.0322 0.7607 0.7589
Echinococcus granulosus g protein coupled receptor 0.0018 0.034 0.0268
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.034 0.0268
Brugia malayi hypothetical protein 0.0018 0.034 0.0301
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.034 0.0268
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.034 0.0268
Schistosoma mansoni opsin-like receptor 0.0018 0.034 0.034
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.034 0.0268
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0787 0.2078
Schistosoma mansoni neuropeptide receptor 0.0018 0.034 0.034
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.034 0.0297
Echinococcus multilocularis g protein coupled receptor 0.0018 0.034 0.0268
Schistosoma mansoni tar DNA-binding protein 0.0065 0.1463 0.1463
Echinococcus multilocularis g protein coupled receptor 0.0018 0.034 0.0268
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.034 0.034
Schistosoma mansoni myosin xvIII 0.0018 0.034 0.034
Brugia malayi Tachykinin-like peptides receptor 99D 0.0018 0.034 0.0301
Echinococcus granulosus dro:myosuppressin receptor 0.0018 0.034 0.0268
Echinococcus granulosus 7tm_1 domain containing protein 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0037 0.0787 0.0894
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus multilocularis orexin receptor type 2 0.0018 0.034 0.0268
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.034 0.0297
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.034 0.034
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.1463 0.1799
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0322 0.7607 1
Brugia malayi follicle stimulating hormone receptor 0.0018 0.034 0.0301
Schistosoma mansoni tar DNA-binding protein 0.0065 0.1463 0.1463
Brugia malayi neuropeptide F receptor 0.0018 0.034 0.0301
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Mycobacterium ulcerans thymidylate synthase 0.0322 0.7607 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0018 0.034 0.0297
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0787 0.0718
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.034 0.0268
Loa Loa (eye worm) thymidylate synthase 0.0322 0.7607 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.034 0.034
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.034 0.034
Onchocerca volvulus 0.003 0.0608 0.0368
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0153 0.3565 0.4074
Schistosoma mansoni tar DNA-binding protein 0.0065 0.1463 0.1463
Echinococcus multilocularis g protein coupled receptor 0.0018 0.034 0.0268
Schistosoma mansoni cpg binding protein 0.003 0.0608 0.0608
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.034 0.034
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0787 0.0894
Brugia malayi G-protein coupled receptor 0.0018 0.034 0.0301
Brugia malayi hypothetical protein 0.0018 0.034 0.0301
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0787 0.2078
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.034 0.0268
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0018 0.034 0.0268
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.034 0.0268
Brugia malayi G-protein coupled receptor 0.0018 0.034 0.0301
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus granulosus alpha 1A adrenergic receptor 0.0018 0.034 0.0268
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0787 0.0898
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.034 0.0268
Brugia malayi RNA binding protein 0.0065 0.1463 0.1799
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.034 0.034
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.034 0.0268
Schistosoma mansoni growth hormone secretagogue receptor 0.0018 0.034 0.034
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0018 0.034 0.0297
Echinococcus granulosus allatostatin A receptor 0.0018 0.034 0.0268
Onchocerca volvulus 0.0037 0.0787 0.0616
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0018 0.034 0.034
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.034 0.0268
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0787 0.0718
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus granulosus somatostatin receptor 0.0018 0.034 0.0268
Brugia malayi hypothetical protein 0.0018 0.034 0.0301
Echinococcus granulosus neuropeptide receptor A26 0.0018 0.034 0.0268
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.034 0.0268
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0322 0.7607 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0322 0.7607 0.5
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0018 0.034 0.034
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus granulosus G protein coupled receptor 139 0.0018 0.034 0.0268
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0322 0.7607 1
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0322 0.7607 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.034 0.0268
Onchocerca volvulus 0.0037 0.0787 0.0616
Echinococcus granulosus g protein coupled receptor 0.0018 0.034 0.0268
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0787 0.2078
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.034 0.0268
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.034 0.034
Brugia malayi hypothetical protein 0.0018 0.034 0.0301
Schistosoma mansoni neuropeptide f receptor 76f 0.0018 0.034 0.034
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0322 0.7607 1
Schistosoma mansoni biogenic amine receptor 0.0018 0.034 0.034
Brugia malayi hypothetical protein 0.0153 0.3565 0.4606
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Schistosoma mansoni hypothetical protein 0.0422 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.034 0.0268
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.034 0.0268
Echinococcus granulosus geminin 0.0175 0.4083 0.4039
Brugia malayi putative neuropeptide receptor NPR1 0.0018 0.034 0.0301
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.034 0.0268
Echinococcus multilocularis neuropeptide receptor 0.0018 0.034 0.0268
Brugia malayi Melatonin receptor type 1A 0.0018 0.034 0.0301
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0018 0.034 0.0301
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Schistosoma mansoni adenoreceptor 0.0018 0.034 0.034
Echinococcus multilocularis serotonin receptor 0.0018 0.034 0.0268
Schistosoma mansoni histamine h1 receptor 0.0018 0.034 0.034
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.034 0.0268
Brugia malayi beta-lactamase 0.0037 0.0787 0.0898
Brugia malayi Dopamine receptor protein 2 0.0018 0.034 0.0301
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus multilocularis neuropeptide receptor A26 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.034 0.0268
Schistosoma mansoni amine GPCR 0.0018 0.034 0.034
Echinococcus multilocularis allatostatin A receptor 0.0018 0.034 0.0268
Brugia malayi hypothetical protein 0.0018 0.034 0.0301
Brugia malayi RE15519p 0.0018 0.034 0.0301
Echinococcus granulosus serotonin receptor 0.0018 0.034 0.0268
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0322 0.7607 0.7607
Onchocerca volvulus 0.0322 0.7607 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.034 0.034
Schistosoma mansoni alpha-1 adrenergic receptor 0.0018 0.034 0.034
Echinococcus multilocularis cpg binding protein 0.0031 0.0648 0.0578
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Brugia malayi thymidylate synthase 0.0322 0.7607 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.034 0.034
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.034 0.0297
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.034 0.0268
Brugia malayi G protein-coupled receptor 0.0018 0.034 0.0301
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.034 0.034
Brugia malayi hypothetical protein 0.0018 0.034 0.0301
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0018 0.034 0.0268
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0787 0.2078
Schistosoma mansoni neuropeptide receptor 0.0018 0.034 0.034
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.034 0.0268
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0118 0.0044
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Brugia malayi hypothetical protein 0.0018 0.034 0.0301
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Brugia malayi TAR-binding protein 0.0065 0.1463 0.1799
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.034 0.0268
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.034 0.0268
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.034 0.034
Schistosoma mansoni hypothetical protein 0.0018 0.034 0.034
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0018 0.034 0.0301
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0018 0.034 0.0301
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Loa Loa (eye worm) melatonin receptor type 1A 0.0018 0.034 0.0297
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.034 0.0268
Trichomonas vaginalis esterase, putative 0.0037 0.0787 0.2078
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Brugia malayi hypothetical protein 0.0018 0.034 0.0301
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.034 0.034
Brugia malayi putative neuropeptide receptor 0.0018 0.034 0.0301
Brugia malayi hypothetical protein 0.0018 0.034 0.0301
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.034 0.0268
Schistosoma mansoni hypothetical protein 0.0175 0.4083 0.4083
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0018 0.034 0.0268
Brugia malayi Serotonin receptor 0.0018 0.034 0.0301
Echinococcus granulosus fmrfamide receptor 0.0018 0.034 0.0268
Echinococcus multilocularis somatostatin receptor 0.0018 0.034 0.0268
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0018 0.034 0.0297
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Loa Loa (eye worm) TAR-binding protein 0.0065 0.1463 0.1796
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0608 0.0654
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.034 0.0268
Echinococcus multilocularis fmrfamide receptor 0.0018 0.034 0.0268
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.1403 0.1403
Loa Loa (eye worm) hypothetical protein 0.0037 0.0787 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0153 0.3565 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.034 0.0268
Echinococcus granulosus peptide allatostatin:somatostatin 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Brugia malayi CXXC zinc finger family protein 0.003 0.0608 0.0658
Echinococcus granulosus thymidylate synthase 0.0322 0.7607 0.7589
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Brugia malayi AKH receptor 0.0018 0.034 0.0301
Brugia malayi Serotonin receptor 0.0018 0.034 0.0301
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.034 0.034
Loa Loa (eye worm) RNA binding protein 0.0065 0.1463 0.1796
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.034 0.0268
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.034 0.0268
Schistosoma mansoni opsin-like receptor 0.0018 0.034 0.034
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Schistosoma mansoni amine GPCR 0.0018 0.034 0.034
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0322 0.7607 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.1463 0.1796
Echinococcus multilocularis neuropeptide s receptor 0.0018 0.034 0.0268
Onchocerca volvulus 0.0037 0.0787 0.0616
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0118 0.0044
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0037 0.0787 0.0894
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Schistosoma mansoni cpg binding protein 0.0031 0.0648 0.0648
Echinococcus granulosus neuropeptide FF receptor 2 0.0018 0.034 0.0268
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0018 0.034 0.034
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0787 0.2078
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.1242 0.0667
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.034 0.0297
Echinococcus multilocularis serotonin receptor 0.0018 0.034 0.0268
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.034 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.034 0.0297
Mycobacterium tuberculosis Hypothetical protein 0.0153 0.3565 0.4074
Loa Loa (eye worm) beta-lactamase 0.0037 0.0787 0.0894
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.034 0.034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.034 0.0268
Schistosoma mansoni neuropeptide receptor 0.0018 0.034 0.034
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.034 0.0268
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.034 0.0268
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.034 0.0268
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.034 0.0268

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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