Detailed information for compound 557069

Basic information

Technical information
  • TDR Targets ID: 557069
  • Name: 1-methyltetrahydrothiophen-1-ium iodide
  • MW: 230.11 | Formula: C5H11IS
  • H donors: 0 H acceptors: 0 LogP: 2.24 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[S+]1CCCC1.[I-]
  • InChi: 1S/C5H11S.HI/c1-6-4-2-3-5-6;/h2-5H2,1H3;1H/q+1;/p-1
  • InChiKey: NCNHVXIIPFWKBR-UHFFFAOYSA-M  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-methylthiolan-1-ium iodide
  • 1-methylthiolanium iodide
  • 28608-92-6
  • Thiophenium, tetrahydro-1-methyl-, iodide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis glutathione reductase, putative 0.0026 0.0148 0.0231
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0406 0.0387
Loa Loa (eye worm) glutathione reductase 0.0076 0.0775 0.2027
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0174 0.2006 0.8837
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.016 0.0419
Echinococcus multilocularis neuroligin 0.0034 0.0247 0.0228
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0384 0.1003
Plasmodium falciparum thioredoxin reductase 0.0026 0.0148 0.0889
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.0148 0.5
Schistosoma mansoni aldehyde dehydrogenase 0.0182 0.2104 0.5139
Treponema pallidum NADH oxidase 0.0026 0.0148 0.5
Echinococcus granulosus neuroligin 0.0034 0.0247 0.041
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0034 0.0247 0.0606
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0026 0.0148 0.0614
Loa Loa (eye worm) hypothetical protein 0.0203 0.2373 0.6203
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0183 0.0403
Schistosoma mansoni neuroligin 3 (S09 family) 0.0034 0.0247 0.0561
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0384 0.1003
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0026 0.0148 0.0231
Brugia malayi Coelomocyte uptake defective protein 5 0.0194 0.2265 0.5919
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0384 0.0898
Giardia lamblia NADH oxidase lateral transfer candidate 0.0026 0.0148 1
Echinococcus granulosus carboxylesterase 5A 0.0203 0.2373 0.4244
Entamoeba histolytica hypothetical protein 0.0037 0.0276 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0026 0.0148 0.0889
Schistosoma mansoni hypothetical protein 0.0047 0.0406 0.0952
Echinococcus granulosus snurportin 1 0.0313 0.3754 0.6734
Loa Loa (eye worm) intermediate filament protein 0.0027 0.016 0.0419
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0114 0.1248
Echinococcus granulosus thioredoxin glutathione reductase 0.0077 0.0788 0.1386
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0193 0.225 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0148 0.1693
Brugia malayi Carboxylesterase family protein 0.0034 0.0247 0.0647
Loa Loa (eye worm) hypothetical protein 0.0034 0.0247 0.0647
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0019 0.006 0.0156
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0087 0.032
Echinococcus granulosus acetylcholinesterase 0.0203 0.2373 0.4244
Brugia malayi Pre-SET motif family protein 0.0029 0.0183 0.0479
Schistosoma mansoni importin beta-1 0.0029 0.0184 0.0405
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0148 0.1693
Onchocerca volvulus 0.0034 0.0247 0.0338
Schistosoma mansoni tar DNA-binding protein 0.0318 0.3826 0.9387
Brugia malayi Carboxylesterase family protein 0.0203 0.2373 0.6203
Schistosoma mansoni lamin 0.0027 0.016 0.0346
Echinococcus multilocularis geminin 0.0338 0.4074 0.4062
Schistosoma mansoni tar DNA-binding protein 0.0318 0.3826 0.9387
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0402
Brugia malayi Carboxylesterase family protein 0.0034 0.0247 0.0647
Entamoeba histolytica hypothetical protein 0.0037 0.0276 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0182 0.2104 0.2088
Loa Loa (eye worm) hypothetical protein 0.0034 0.0247 0.0647
Brugia malayi RNA recognition motif domain containing protein 0.0318 0.3826 1
Echinococcus multilocularis acetylcholinesterase 0.0203 0.2373 0.2358
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0026 0.0148 0.0889
Brugia malayi Carboxylesterase family protein 0.0034 0.0247 0.0647
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0174 0.2006 0.8837
Mycobacterium ulcerans aldehyde dehydrogenase 0.0182 0.2104 1
Echinococcus multilocularis GPCR, family 2 0.0047 0.0406 0.0387
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0114 0.0104
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0026 0.0148 0.0316
Echinococcus granulosus muscleblind protein 0.0152 0.1726 0.3077
Trypanosoma cruzi trypanothione reductase, putative 0.0076 0.0775 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0026 0.0148 0.0614
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0203 0.2373 0.5804
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0174 0.2006 0.8837
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0197 0.2297 0.4107
Schistosoma mansoni tar DNA-binding protein 0.0318 0.3826 0.9387
Brugia malayi intermediate filament protein 0.0027 0.016 0.0419
Echinococcus granulosus geminin 0.0338 0.4074 0.7312
Brugia malayi Thioredoxin reductase 0.0076 0.0775 0.2027
Brugia malayi Carboxylesterase family protein 0.0034 0.0247 0.0647
Echinococcus multilocularis BC026374 protein (S09 family) 0.0034 0.0247 0.0228
Plasmodium falciparum importin beta, putative 0.0029 0.0184 0.1414
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0034 0.0247 0.0473
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0183 0.0403
Echinococcus granulosus para nitrobenzyl esterase 0.0034 0.0247 0.041
Trypanosoma cruzi trypanothione reductase, putative 0.0026 0.0148 0.1693
Loa Loa (eye worm) hypothetical protein 0.0047 0.0406 0.1061
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0276 0.0461
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0406 0.1061
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0026 0.0148 0.0889
Trypanosoma brucei trypanothione reductase 0.0076 0.0775 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0384 0.0365
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0114 0.0104
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0276 0.0256
Echinococcus multilocularis muscleblind protein 1 0.0152 0.1726 0.171
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0193 0.225 1
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0184 0.0164
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0182 0.2104 1
Echinococcus granulosus lamin 0.0027 0.016 0.0253
Leishmania major trypanothione reductase 0.0076 0.0775 0.3626
Mycobacterium ulcerans aldehyde dehydrogenase 0.0182 0.2104 1
Echinococcus multilocularis neuropeptide s receptor 0.0456 0.5565 0.5556
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0148 0.0614
Schistosoma mansoni mucolipin 0.0178 0.206 0.5031
Echinococcus granulosus mucolipin 3 0.0194 0.2265 0.4048
Mycobacterium tuberculosis Carboxylesterase LipT 0.0034 0.0247 0.0473
Echinococcus granulosus lamin dm0 0.0027 0.016 0.0253
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0184 0.0788
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.1683 0.4398
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0026 0.0148 0.0614
Loa Loa (eye worm) TAR-binding protein 0.0318 0.3826 1
Plasmodium falciparum glutathione reductase 0.0026 0.0148 0.0889
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0313 0.3754 0.9811
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0026 0.0148 0.1693
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0148 0.1693
Echinococcus multilocularis para nitrobenzyl esterase 0.0034 0.0247 0.0228
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0087 0.0883
Loa Loa (eye worm) hypothetical protein 0.0034 0.0247 0.0647
Schistosoma mansoni intermediate filament proteins 0.0027 0.016 0.0346
Schistosoma mansoni tar DNA-binding protein 0.0318 0.3826 0.9387
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0384 0.0898
Schistosoma mansoni hypothetical protein 0.0313 0.3754 0.9209
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0406 0.0696
Loa Loa (eye worm) hypothetical protein 0.0203 0.2373 0.6203
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0174 0.2006 0.8837
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0183 0.0403
Plasmodium vivax importin-beta 2, putative 0.0029 0.0184 0.1414
Loa Loa (eye worm) hypothetical protein 0.0298 0.3574 0.9342
Schistosoma mansoni ran 0.0022 0.0087 0.0164
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0148 0.1693
Onchocerca volvulus 0.0029 0.0183 0.009
Echinococcus multilocularis carboxylesterase 5A 0.0203 0.2373 0.2358
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0384 0.0656
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0184 0.2172
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0406 0.1061
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0087 0.0227
Mycobacterium ulcerans aldehyde dehydrogenase 0.0182 0.2104 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0174 0.2006 0.8837
Onchocerca volvulus 0.0034 0.0247 0.0338
Brugia malayi TAR-binding protein 0.0318 0.3826 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.016 0.0419
Schistosoma mansoni hypothetical protein 0.0047 0.0406 0.0952
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0384 0.0898
Brugia malayi Pre-SET motif family protein 0.0204 0.2382 0.6226
Loa Loa (eye worm) hypothetical protein 0.0034 0.0247 0.0647
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0148 0.1693
Trichomonas vaginalis mercuric reductase, putative 0.0026 0.0148 0.0231
Onchocerca volvulus 0.0034 0.0247 0.0338
Entamoeba histolytica hypothetical protein 0.0024 0.0114 0.1462
Brugia malayi Importin beta-1 subunit 0.0029 0.0184 0.0481
Schistosoma mansoni hypothetical protein 0.0047 0.0406 0.0952
Loa Loa (eye worm) hypothetical protein 0.0034 0.0247 0.0647
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0318 0.3826 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0026 0.0148 0.5
Echinococcus multilocularis neuropeptide receptor A26 0.0456 0.5565 0.5556
Echinococcus multilocularis lamin dm0 0.0027 0.016 0.014
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0087 0.0883
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0384 0.0365
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0026 0.0148 0.0128
Schistosoma mansoni lamin 0.0027 0.016 0.0346
Loa Loa (eye worm) hypothetical protein 0.0152 0.1726 0.4512
Loa Loa (eye worm) carboxylesterase 0.0034 0.0247 0.0647
Loa Loa (eye worm) RNA binding protein 0.0318 0.3826 1
Trichomonas vaginalis set domain proteins, putative 0.0232 0.2737 1
Echinococcus multilocularis snurportin 1 0.0313 0.3754 0.3741
Onchocerca volvulus 0.0034 0.0247 0.0338
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0148 0.1693
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.017 0.027
Schistosoma mansoni gliotactin 0.0034 0.0247 0.0561
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0148 0.0614
Echinococcus multilocularis muscleblind protein 0.0152 0.1726 0.171
Schistosoma mansoni hypothetical protein 0.0338 0.4074 1
Echinococcus granulosus intermediate filament protein 0.0027 0.016 0.0253
Echinococcus multilocularis mucolipin 3 0.0194 0.2265 0.2249
Echinococcus multilocularis tar DNA binding protein 0.0318 0.3826 0.3814
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0184 0.2172
Loa Loa (eye worm) thioredoxin reductase 0.0076 0.0775 0.2027
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0406 0.1061
Plasmodium falciparum thioredoxin reductase 0.0076 0.0775 1
Leishmania major GTP-binding protein, putative 0.0022 0.0087 0.032
Mycobacterium ulcerans carboxylesterase, LipT 0.0034 0.0247 0.0509
Loa Loa (eye worm) hypothetical protein 0.0034 0.0247 0.0647
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.1683 0.4398
Echinococcus multilocularis acetylcholinesterase 0.0203 0.2373 0.2358
Brugia malayi hypothetical protein 0.0037 0.0276 0.0721
Loa Loa (eye worm) carboxylesterase 0.0203 0.2373 0.6203
Toxoplasma gondii NADPH-glutathione reductase 0.0026 0.0148 0.0614
Echinococcus granulosus GPCR family 2 0.0047 0.0406 0.0696
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0148 0.1693
Onchocerca volvulus 0.0232 0.2737 1
Entamoeba histolytica hypothetical protein 0.0037 0.0276 1
Entamoeba histolytica hypothetical protein 0.0037 0.0276 1
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0276 0.0631
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.1092 0.2854
Toxoplasma gondii aldehyde dehydrogenase 0.0182 0.2104 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.1092 0.2854
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0034 0.0247 0.0561
Loa Loa (eye worm) hypothetical protein 0.0029 0.0184 0.0481
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0183 0.0403
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0183 0.0784
Loa Loa (eye worm) hypothetical protein 0.0034 0.0247 0.0647
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0183 0.0295
Mycobacterium tuberculosis Probable reductase 0.0174 0.2006 0.8837
Echinococcus granulosus neuropeptide s receptor 0.0456 0.5565 1
Trichomonas vaginalis spcc417.12 protein, putative 0.0034 0.0247 0.0606
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0183 0.0164
Plasmodium vivax thioredoxin reductase, putative 0.0076 0.0775 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0019 0.006 0.0156
Plasmodium falciparum glutathione reductase 0.0076 0.0775 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0182 0.2104 0.3758
Echinococcus granulosus acetylcholinesterase 0.0203 0.2373 0.4244
Brugia malayi RNA, U transporter 1 0.0083 0.0864 0.2259
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0087 0.0067
Echinococcus granulosus neuropeptide receptor A26 0.0456 0.5565 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.0148 0.5
Brugia malayi glutathione reductase 0.0076 0.0775 0.2027
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0026 0.0148 0.0889
Loa Loa (eye worm) mucolipin 1 0.0194 0.2265 0.5919
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.2382 0.6226
Schistosoma mansoni hypothetical protein 0.0037 0.0276 0.0631
Schistosoma mansoni ran 0.0022 0.0087 0.0164
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0034 0.0247 0.0473
Loa Loa (eye worm) hypothetical protein 0.0152 0.1726 0.4512
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0183 0.0164
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0182 0.2104 0.9303
Loa Loa (eye worm) hypothetical protein 0.0029 0.0183 0.0479
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0034 0.0247 0.0561
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0087 0.0227
Plasmodium vivax glutathione reductase, putative 0.0076 0.0775 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0148 0.1693
Brugia malayi Carboxylesterase family protein 0.0203 0.2373 0.6203
Echinococcus granulosus BC026374 protein S09 family 0.0034 0.0247 0.041
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0114 0.0104
Loa Loa (eye worm) acetylcholinesterase 1 0.0203 0.2373 0.6203
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0087 0.012
Echinococcus multilocularis musashi 0.0027 0.016 0.014
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0034 0.0247 0.0228
Schistosoma mansoni hypothetical protein 0.0047 0.0406 0.0952
Echinococcus multilocularis thioredoxin glutathione reductase 0.0077 0.0788 0.077
Schistosoma mansoni hypothetical protein 0.0338 0.4074 1
Brugia malayi RNA binding protein 0.0318 0.3826 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0193 0.225 1
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0034 0.0247 0.041
Schistosoma mansoni mucolipin 0.0194 0.2265 0.5536
Onchocerca volvulus 0.0034 0.0247 0.0338
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.016 0.0419
Echinococcus granulosus importin subunit beta 1 0.0029 0.0184 0.0296
Schistosoma mansoni tar DNA-binding protein 0.0318 0.3826 0.9387
Toxoplasma gondii thioredoxin reductase 0.0076 0.0775 0.3626
Loa Loa (eye worm) carboxylesterase 0.0034 0.0247 0.0647
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0034 0.0247 0.0561
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0026 0.0148 0.0387
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0076 0.0775 0.2985
Schistosoma mansoni BC026374 protein (S09 family) 0.0034 0.0247 0.0561
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0148 0.1693
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0298 0.3574 0.9342
Schistosoma mansoni acetylcholinesterase 0.0034 0.0247 0.0561
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0384 0.0656
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0197 0.2297 0.2282
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0087 0.0883
Echinococcus multilocularis lamin 0.0027 0.016 0.014
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0026 0.0148 0.1693
Mycobacterium tuberculosis Probable oxidoreductase 0.0193 0.225 1
Brugia malayi hypothetical protein 0.0034 0.0247 0.0647
Schistosoma mansoni hypothetical protein 0.0101 0.1092 0.2644
Leishmania major importin beta-1 subunit, putative 0.0024 0.0114 0.0453
Plasmodium vivax SET domain protein, putative 0.0029 0.0183 0.1403
Echinococcus granulosus tar DNA binding protein 0.0318 0.3826 0.6864
Brugia malayi Muscleblind-like protein 0.0152 0.1726 0.4512
Schistosoma mansoni aldehyde dehydrogenase 0.0182 0.2104 0.5139
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0148 0.1693

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.