Detailed information for compound 55879

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 843.987 | Formula: C43H53N7O9S
  • H donors: 7 H acceptors: 8 LogP: 3.95 Rotable bonds: 28
    Rule of 5 violations (Lipinski): 3
  • SMILES: OC(=O)C[C@H](N(C(=O)[C@@H](NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)OC(C)(C)C)CCCCNC(=O)/C=C/c1cccs1)C)C(=O)N[C@H](C(=O)N)Cc1ccccc1
  • InChi: 1S/C43H53N7O9S/c1-43(2,3)59-42(58)49-34(24-28-26-46-31-17-9-8-16-30(28)31)39(55)47-32(18-10-11-21-45-36(51)20-19-29-15-12-22-60-29)41(57)50(4)35(25-37(52)53)40(56)48-33(38(44)54)23-27-13-6-5-7-14-27/h5-9,12-17,19-20,22,26,32-35,46H,10-11,18,21,23-25H2,1-4H3,(H2,44,54)(H,45,51)(H,47,55)(H,48,56)(H,49,58)(H,52,53)/b20-19+/t32-,33-,34?,35-/m0/s1
  • InChiKey: PFDXGRUVVNQAQW-AAYKEFHDSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cholecystokinin B receptor Starlite/ChEMBL References
Homo sapiens cholecystokinin A receptor References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132882 All targets in OG5_132882
Brugia malayi hypothetical protein Get druggable targets OG5_132882 All targets in OG5_132882
Brugia malayi sulfakinin receptor protein Get druggable targets OG5_132882 All targets in OG5_132882
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus rhodopsin orphan GPCR cholecystokinin A receptor 428 aa 373 aa 19.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0404 0.0888 0.0888
Brugia malayi Cytochrome P450 family protein 0.0083 0.0133 0.0144
Loa Loa (eye worm) cytochrome P450 family protein 0.0083 0.0133 0.0138
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0089 0.0089
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0076 0.0082
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Echinococcus granulosus nuclear receptor nhr 48 0.0065 0.0089 0.0089
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0042 0.0035 0.0177
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0076 0.0082
Echinococcus multilocularis peptidase Clp (S14 family) 0.0056 0.0068 0.0068
Brugia malayi neuropeptide F receptor 0.0534 0.1194 0.1289
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0138 0.0261 0.0281
Loa Loa (eye worm) pyruvate kinase 0.007 0.0101 0.0104
Schistosoma mansoni nAChR subunit 0.0036 0.0022 0.0022
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0111 0.0197 0.0678
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0125 0.0232 0.0232
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0047 0.0163
Brugia malayi jmjC domain containing protein 0.0068 0.0096 0.0103
Loa Loa (eye worm) hypothetical protein 0.0073 0.0108 0.0111
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0245 0.0514 0.0514
Entamoeba histolytica hypothetical protein 0.0118 0.0215 0.0645
Brugia malayi MH1 domain containing protein 0.0029 0.0005 0.0005
Echinococcus granulosus g protein coupled receptor 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0053 0.0061 0.006
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0038 0.1039
Echinococcus granulosus g protein coupled receptor 0.0534 0.1194 0.1194
Echinococcus granulosus histone lysine methyltransferase setb 0.013 0.0243 0.0243
Onchocerca volvulus Bile acid receptor homolog 0.0138 0.0261 0.1024
Schistosoma mansoni nAChR subunit 0.0036 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0053 0.0061 0.0303
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0113 0.0203 0.0605
Schistosoma mansoni twik family of potassium channels-related 0.0063 0.0084 0.0084
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0111 0.0197 0.5379
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0056 0.0068 0.0151
Loa Loa (eye worm) hypothetical protein 0.0037 0.0024 0.0021
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0029 0.0144
Echinococcus granulosus neuropeptide FF receptor 2 0.0534 0.1194 0.1194
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0042 0.0035 0.0177
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0042 0.0035 0.0177
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0042 0.0035 0.0079
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1261 0.2909 1
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0061 0.1655
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0048 0.0049 0.0049
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0027 0.0093
Echinococcus multilocularis neuropeptide receptor 0.0534 0.1194 0.1194
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0592 0.2036
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0036 0.0022 0.0024
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0042 0.0035 0.0038
Echinococcus multilocularis serotonin receptor 0.2487 0.5798 0.5798
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0138 0.0261 0.0281
Loa Loa (eye worm) TWK-7 protein 0.0063 0.0084 0.0086
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0111 0.0197 0.5379
Brugia malayi Calcitonin receptor-like protein seb-1 0.0105 0.0183 0.0198
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0534 0.1194 0.1194
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0042 0.0035 0.0177
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.0069 0.0075
Schistosoma mansoni cpg binding protein 0.0064 0.0088 0.0088
Schistosoma mansoni nAChR subunit 0.0036 0.0022 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0042 0.0035 0.0177
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0053 0.0061 0.0135
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0019 0.002
Echinococcus granulosus voltage gated potassium channel 0.0031 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0257 0.0542 0.0581
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.0137 0.3744
Loa Loa (eye worm) hypothetical protein 0.0054 0.0065 0.0064
Loa Loa (eye worm) glutaminase 0.088 0.201 0.2165
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0534 0.1194 0.1194
Onchocerca volvulus 0.0534 0.1194 0.5036
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0044 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0138 0.0261 0.0276
Echinococcus granulosus importin subunit beta 1 0.0059 0.0076 0.0076
Onchocerca volvulus 0.0065 0.0089 0.0288
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0068 0.0097 0.0097
Schistosoma mansoni lipoxygenase 0.0115 0.0207 0.0207
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0042 0.0035 0.0177
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0036 0.0022 0.0022
Schistosoma mansoni neuropeptide F-like receptor 0.0534 0.1194 0.1194
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.0061 0.0066
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Chlamydia trachomatis pyruvate kinase 0.007 0.0101 0.4723
Loa Loa (eye worm) transcription factor SMAD2 0.0772 0.1756 0.1891
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.0122 0.027
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0019 0.0019
Onchocerca volvulus 0.0063 0.0084 0.0267
Onchocerca volvulus 0.0068 0.0097 0.0322
Schistosoma mansoni ran 0.0044 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.1327 0.3064 0.3064
Echinococcus granulosus voltage dependent calcium channel 0.0073 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0943 0.2158 0.2326
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0027 0.0029
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0178 0.0355 0.0789
Echinococcus granulosus neuropeptide receptor A26 0.0534 0.1194 0.1194
Schistosoma mansoni ap endonuclease 0.0078 0.0121 0.0121
Onchocerca volvulus 0.0117 0.0213 0.0818
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Echinococcus granulosus RUN 0.0041 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0634 0.143 0.143
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0534 0.1194 0.1194
Onchocerca volvulus 0.0534 0.1194 0.5036
Echinococcus granulosus potassium channel subfamily K 8 0.0063 0.0084 0.0084
Loa Loa (eye worm) serotonin transporter b 0.028 0.0597 0.0639
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0044 0.0039 0.0135
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0115 0.0207 0.0207
Plasmodium falciparum flap endonuclease 1 0.0057 0.0071 0.1935
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.008 0.0081
Plasmodium falciparum potassium channel 0.0063 0.0084 0.2299
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0048 0.0049 0.0049
Onchocerca volvulus 0.0534 0.1194 0.5036
Loa Loa (eye worm) hypothetical protein 0.0138 0.0261 0.0276
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0031 0.001 0.001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0119 0.0217 0.1081
Mycobacterium ulcerans integral membrane protein 0.0037 0.0023 0.0113
Echinococcus granulosus rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0178 0.0355 0.0789
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0042 0.0035 0.0177
Loa Loa (eye worm) runx1 0.0118 0.0215 0.0227
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0019 0.002
Mycobacterium tuberculosis Conserved protein 0.0079 0.0122 0.027
Brugia malayi hypothetical protein 0.0534 0.1194 0.1289
Brugia malayi Serotonin receptor 0.0988 0.2264 0.2444
Toxoplasma gondii CAAX amino terminal protease family protein 0.0037 0.0023 0.0619
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0036 0.0022 0.0019
Echinococcus multilocularis pyruvate kinase 0.007 0.0101 0.0101
Schistosoma mansoni DNA polymerase eta 0.0049 0.0053 0.0053
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0039 0.0029 0.0065
Loa Loa (eye worm) nuclear receptor NHR-67 0.0065 0.0089 0.0091
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0069 0.0237
Echinococcus granulosus neuropeptides capa receptor 0.0534 0.1194 0.1194
Echinococcus multilocularis g protein coupled receptor 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Schistosoma mansoni amine GPCR 0.0534 0.1194 0.1194
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0138 0.0261 0.0261
Loa Loa (eye worm) MH2 domain-containing protein 0.0053 0.006 0.006
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0036 0.0022 0.0022
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0138 0.0261 0.0261
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0534 0.1194 0.1194
Schistosoma mansoni biogenic amine receptor 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.006 0.0077 0.0078
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0036 0.0022 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0042 0.0035 0.0079
Schistosoma mansoni nuclear hormone receptor 0.0138 0.0261 0.0261
Trichomonas vaginalis esterase, putative 0.0079 0.0122 0.0418
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0534 0.1194 0.1194
Trichomonas vaginalis glutaminase, putative 0.088 0.201 0.6908
Brugia malayi Pyruvate kinase, muscle isozyme 0.007 0.0101 0.0109
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0073 0.0109 0.0375
Brugia malayi nuclear hormone receptor family member nhr-6 0.0065 0.0089 0.0096
Brugia malayi acetyltransferase, GNAT family protein 0.016 0.0314 0.0339
Echinococcus granulosus biogenic amine 5HT receptor 0.2487 0.5798 0.5798
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0122 0.0418
Echinococcus multilocularis serotonin receptor 0.2487 0.5798 0.5798
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0534 0.1194 0.1194
Leishmania major sterol C-24 reductase, putative 0.0046 0.0045 0.0049
Brugia malayi ERG2 and Sigma1 receptor like protein 0.3957 0.9263 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0073 0.0108 0.0108
Brugia malayi glutaminase DH11.1 0.088 0.201 0.217
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0049 0.0052
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0534 0.1194 0.1194
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1261 0.2909 1
Brugia malayi G-protein coupled receptor 0.0534 0.1194 0.1289
Brugia malayi nuclear hormone receptor family member odr-7 0.0065 0.0089 0.0096
Brugia malayi cytochrome P450 0.0042 0.0035 0.0038
Brugia malayi CAAX amino terminal protease family protein 0.0177 0.0355 0.0383
Schistosoma mansoni inositol monophosphatase 0.0038 0.0027 0.0027
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0534 0.1194 0.1194
Brugia malayi hypothetical protein 0.0534 0.1194 0.1289
Brugia malayi RE15519p 0.0534 0.1194 0.1289
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0111 0.0197 0.0678
Echinococcus multilocularis neuropeptide s receptor 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0105 0.0183 0.0192
Entamoeba histolytica acyl-coA synthetase, putative 0.0053 0.0061 0.0138
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Schistosoma mansoni jumonji/arid domain-containing protein 0.0068 0.0096 0.0096
Trichomonas vaginalis pyruvate kinase, putative 0.007 0.0101 0.0347
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Brugia malayi Carboxylesterase family protein 0.0404 0.0888 0.0958
Echinococcus multilocularis rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0122 0.0122
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0534 0.1194 0.1194
Echinococcus multilocularis G protein coupled receptor 139 0.0534 0.1194 0.1194
Toxoplasma gondii ABC1 family protein 0.0079 0.0122 0.3317
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.013 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Echinococcus granulosus dro:myosuppressin receptor 0.0534 0.1194 0.1194
Schistosoma mansoni microtubule-associated protein tau 0.427 1 1
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0183 0.0367 1
Echinococcus granulosus pyruvate kinase 0.0036 0.0021 0.0021
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0119 0.0217 0.0235
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0063 0.0084 0.0091
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0078 0.0121 0.0131
Onchocerca volvulus 0.0534 0.1194 0.5036
Trichomonas vaginalis flap endonuclease-1, putative 0.0057 0.0071 0.0244
Echinococcus granulosus g-protein coupled receptor 0.0534 0.1194 0.1194
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0138 0.0261 0.0281
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0138 0.0261 0.0261
Echinococcus granulosus geminin 0.147 0.3401 0.3401
Onchocerca volvulus 0.0091 0.0151 0.0555
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.013 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Schistosoma mansoni twik family of potassium channels-related 0.0063 0.0084 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0138 0.0261 0.0281
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.1327 0.3064 0.3307
Loa Loa (eye worm) hypothetical protein 0.0175 0.0348 0.0371
Plasmodium falciparum potassium channel 0.0063 0.0084 0.2299
Brugia malayi hypothetical protein 0.0063 0.0084 0.0091
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0061 0.0303
Schistosoma mansoni neuropeptide F-like receptor 0.0534 0.1194 0.1194
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0091 0.0151 0.0151
Onchocerca volvulus 0.0048 0.0049 0.0113
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0245 0.0514 0.0514
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.09 0.2057 0.2216
Mycobacterium ulcerans thymidylate synthase 0.013 0.0242 0.1205
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0078 0.0121 0.0269
Trypanosoma cruzi C-14 sterol reductase, putative 0.0046 0.0045 0.0049
Echinococcus multilocularis acetylcholinesterase 0.0404 0.0888 0.0888
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0122 0.0418
Loa Loa (eye worm) hypothetical protein 0.0048 0.0049 0.0047
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0036 0.0022 0.0022
Leishmania major hypothetical protein, conserved 0.0063 0.0084 0.0091
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0138 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0063 0.0084 0.0084
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0048 0.0049 0.0049
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0183 0.0367 0.0396
Echinococcus multilocularis rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Brugia malayi Tachykinin-like peptides receptor 99D 0.0534 0.1194 0.1289
Onchocerca volvulus 0.0084 0.0135 0.0485
Schistosoma mansoni cpg binding protein 0.0064 0.0088 0.0088
Echinococcus multilocularis FTZ F1 alpha 0.0138 0.0261 0.0261
Echinococcus granulosus tm gpcr rhodopsin 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0073 0.0109 0.0112
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0069 0.0237
Schistosoma mansoni amine GPCR 0.0929 0.2127 0.2127
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0065 0.0089 0.0288
Entamoeba histolytica CAAX amino terminal protease family 0.0037 0.0023 0.0012
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0019 0.002
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0534 0.1194 0.1194
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0367 0.1261
Leishmania major importin beta-1 subunit, putative 0.0048 0.005 0.0054
Giardia lamblia Flap structure-specific endonuclease 0.0057 0.0071 0.0244
Onchocerca volvulus 0.0138 0.0261 0.1024
Mycobacterium ulcerans recombinase A 0.0118 0.0214 0.1063
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0036 0.0022 0.0024
Loa Loa (eye worm) hypothetical protein 0.0178 0.0356 0.0379
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0122 0.0418
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Echinococcus multilocularis microtubule associated protein 2 0.427 1 1
Schistosoma mansoni tar DNA-binding protein 0.007 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0054 0.0065 0.0064
Echinococcus multilocularis voltage dependent calcium channel 0.0125 0.0232 0.0232
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0042 0.0035 0.0038
Schistosoma mansoni zinc finger protein 0.0065 0.0089 0.0089
Onchocerca volvulus 0.028 0.0597 0.247
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0049 0.1322
Schistosoma mansoni hypothetical protein 0.0867 0.198 0.198
Loa Loa (eye worm) intermediate filament protein 0.0117 0.0213 0.0224
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0027 0.0029
Echinococcus granulosus hypothetical protein 0.0534 0.1194 0.1194
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0024 0.0054
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0534 0.1194 0.1289
Loa Loa (eye worm) hypothetical protein 0.0125 0.0232 0.0245
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0118 0.0214 1
Plasmodium vivax pyruvate kinase 2, putative 0.0036 0.0021 0.0568
Brugia malayi Nuclear hormone receptor E75 0.0065 0.0089 0.0096
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0068 0.0097 0.0097
Echinococcus granulosus G protein coupled receptor 139 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0068 0.0097 0.01
Onchocerca volvulus 0.0039 0.0029 0.0029
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0177 0.0355 0.0383
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0534 0.1194 0.1194
Mycobacterium leprae Conserved hypothetical protein 0.069 0.1563 1
Schistosoma mansoni nAChR subunit 0.0036 0.0022 0.0022
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.0122 0.0606
Toxoplasma gondii hypothetical protein 0.006 0.0077 0.2102
Brugia malayi Melatonin receptor type 1A 0.0534 0.1194 0.1289
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0138 0.0261 0.0276
Mycobacterium ulcerans glutaminase 0.088 0.201 1
Echinococcus multilocularis neuropeptides capa receptor 0.0534 0.1194 0.1194
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0038 0.0131
Brugia malayi Muscleblind-like protein 0.0175 0.0348 0.0376
Schistosoma mansoni hypothetical protein 0.0033 0.0014 0.0014
Echinococcus multilocularis sodium and chloride dependent glycine 0.0048 0.0049 0.0049
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0006 0.0154
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0048 0.0049 0.0049
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0048 0.0049 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0534 0.1194 0.1194
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0125 0.0232 0.0232
Toxoplasma gondii pyruvate kinase PyK1 0.007 0.0101 0.2751
Trypanosoma cruzi DNA repair protein, putative 0.0036 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.0068 0.0097 0.01
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0078 0.0121 0.0131
Brugia malayi Cation transporter family protein 0.0036 0.0022 0.0024
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0073 0.0109 0.0117
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0367 0.1261
Toxoplasma gondii exonuclease III APE 0.0078 0.0121 0.3295
Schistosoma mansoni biogenic amine (5HT) receptor 0.2487 0.5798 0.5798
Echinococcus granulosus thymidylate synthase 0.013 0.0242 0.0242
Trypanosoma cruzi DNA repair protein, putative 0.0036 0.0022 0.0023
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0102 0.0176 0.0176
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0048 0.0049 0.0049
Echinococcus multilocularis glycine receptor subunit beta 0.0036 0.0022 0.0022
Echinococcus multilocularis lamin b receptor 0.0046 0.0045 0.0045
Echinococcus granulosus neuropeptide Y receptor 0.0534 0.1194 0.1194
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0085 0.0137 0.6428
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Echinococcus multilocularis g protein coupled receptor 0.0534 0.1194 0.1194
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0534 0.1194 0.1194
Echinococcus granulosus rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.1819 0.4223 0.9384
Echinococcus granulosus rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Loa Loa (eye worm) dihydrofolate reductase 0.0053 0.0061 0.0061
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0036 0.0022 0.0024
Giardia lamblia Hypothetical protein 0.0177 0.0355 0.1219
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.0101 0.0338
Schistosoma mansoni hypothetical protein 0.0042 0.0035 0.0035
Leishmania major potassium channel subunit-like protein 0.0063 0.0084 0.0091
Brugia malayi orphan nuclear receptor NR2E1 0.0065 0.0089 0.0096
Loa Loa (eye worm) beta-lactamase 0.0079 0.0122 0.0126
Echinococcus multilocularis muscleblind protein 1 0.0175 0.0348 0.0348
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.005 0.0054
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0006 0.0154
Schistosoma mansoni alpha-1 adrenergic receptor 0.0534 0.1194 0.1194
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0183 0.0367 0.0396
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.1327 0.3064 1
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0048 0.0049 0.0052
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0102 0.0176 0.019
Entamoeba histolytica Ran family GTPase 0.0044 0.0039 0.0067
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0534 0.1194 0.1194
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0063 0.0084 0.0091
Loa Loa (eye worm) hypothetical protein 0.0079 0.0122 0.0126
Trypanosoma cruzi pyruvate kinase 2, putative 0.007 0.0101 0.0109
Loa Loa (eye worm) hypothetical protein 0.0138 0.0261 0.0276
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0088 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Trichomonas vaginalis spcc417.12 protein, putative 0.0068 0.0097 0.0334
Brugia malayi hypothetical protein 0.0534 0.1194 0.1289
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0178 0.0356 0.1108
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0063 0.0084 0.029
Schistosoma mansoni neuropeptide receptor 0.0534 0.1194 0.1194
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0042 0.0035 0.0177
Loa Loa (eye worm) hypothetical protein 0.0039 0.0029 0.0026
Leishmania major DNA polymerase eta, putative 0.0035 0.0018 0.002
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0031 0.001 0.0011
Schistosoma mansoni P2X receptor subunit 0.0069 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Loa Loa (eye worm) hypothetical protein 0.0072 0.0105 0.0108
Echinococcus multilocularis acetylcholinesterase 0.0404 0.0888 0.0888
Echinococcus multilocularis rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0079 0.0124 0.0615
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0102 0.0176 0.8237
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0183 0.0367 0.0396
Trypanosoma brucei DNA polymerase eta, putative 0.0049 0.0053 0.0057
Trypanosoma brucei pyruvate kinase 1, putative 0.007 0.0101 0.0109
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0111 0.0198 0.0209
Giardia lamblia Pyruvate kinase 0.0036 0.0021 0.0072
Brugia malayi Doublecortin family protein 0.0041 0.0033 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0122 0.0131
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0029 0.0031
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0019 0.0065
Onchocerca volvulus 0.013 0.0243 0.0949
Schistosoma mansoni cpg binding protein 0.0061 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.1327 0.3064 0.3064
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0063 0.0084 0.0086
Leishmania major hypothetical protein, conserved 0.0053 0.0061 0.0066
Brugia malayi Nuclear hormone receptor-like 1 0.0138 0.0261 0.0281
Treponema pallidum exodeoxyribonuclease (exoA) 0.0078 0.0121 0.0416
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Onchocerca volvulus 0.013 0.0242 0.0945
Loa Loa (eye worm) hypothetical protein 0.0049 0.0051 0.005
Brugia malayi Dopamine receptor protein 2 0.0534 0.1194 0.1289
Echinococcus multilocularis p2X purinoceptor 4 0.0069 0.01 0.01
Loa Loa (eye worm) DR-78 0.0065 0.0089 0.0091
Onchocerca volvulus 0.0534 0.1194 0.5036
Brugia malayi exodeoxyribonuclease III family protein 0.0078 0.0121 0.0131
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0069 0.0075
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Echinococcus granulosus ecdysone induced protein 78C 0.0138 0.0261 0.0261
Entamoeba histolytica CAAX amino terminal protease family 0.0037 0.0023 0.0012
Loa Loa (eye worm) hypothetical protein 0.0449 0.0994 0.1068
Brugia malayi Pre-SET motif family protein 0.09 0.2057 0.222
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0138 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Echinococcus multilocularis g protein coupled receptor 0.0534 0.1194 0.1194
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Echinococcus multilocularis thioredoxin glutathione reductase 0.0079 0.0122 0.0122
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0125 0.0232 0.0232
Echinococcus granulosus neuropeptides capa receptor 0.0534 0.1194 0.1194
Schistosoma mansoni tar DNA-binding protein 0.007 0.0101 0.0101
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0137 0.3744
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0019 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.013 0.0243 0.0243
Echinococcus granulosus thyroid hormone receptor alpha 0.0065 0.0089 0.0089
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0138 0.0261 0.0261
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0036 0.0022 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0042 0.0035 0.0079
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0397 0.0873 0.2806
Toxoplasma gondii pyruvate kinase PyKII 0.0036 0.0021 0.0568
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.0137 0.0684
Leishmania major cytochrome p450-like protein 0.0042 0.0035 0.0038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1261 0.2909 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0079 0.0124 0.0128
Treponema pallidum sodium- and chloride- dependent transporter 0.028 0.0597 0.2052
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0119 0.0217 0.0217
Echinococcus granulosus p2X purinoceptor 4 0.0069 0.01 0.01
Schistosoma mansoni BC026374 protein (S09 family) 0.0068 0.0097 0.0097
Trypanosoma cruzi cytochrome P450, putative 0.0079 0.0124 0.0133
Mycobacterium ulcerans lipase LipD 0.0079 0.0122 0.0606
Onchocerca volvulus 0.0063 0.0084 0.0267
Loa Loa (eye worm) ACC-1 protein 0.0036 0.0022 0.0019
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0534 0.1194 0.1284
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0027 0.0027
Trichomonas vaginalis set domain proteins, putative 0.1024 0.2349 0.8074
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0063 0.0084 0.0187
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0036 0.0022 0.0022
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0178 0.0355 0.0789
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.0122 0.027
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Loa Loa (eye worm) hypothetical protein 0.3157 0.7378 0.7964
Schistosoma mansoni thyroid hormone receptor 0.0138 0.0261 0.0261
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0138 0.0261 0.0281
Echinococcus granulosus retinoic acid receptor rxr beta a 0.1635 0.3789 0.3789
Schistosoma mansoni steroid hormone receptor ad4bp 0.0138 0.0261 0.0261
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0134 0.0252 0.0252
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0245 0.0514 0.0514
Onchocerca volvulus 0.0534 0.1194 0.5036
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0036 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0039 0.0029 0.0026
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0063 0.0084 0.0091
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0068 0.0097 0.0216
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0049 0.0049
Schistosoma mansoni neuropeptide f receptor 76f 0.0534 0.1194 0.1194
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0042 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.0085 0.0137 0.0143
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0073 0.0109 0.0375
Loa Loa (eye worm) hypothetical protein 0.0091 0.0151 0.0158
Echinococcus multilocularis lamin dm0 0.0117 0.0213 0.0213
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0125 0.0232 0.0232
Schistosoma mansoni neuropeptide receptor 0.0534 0.1194 0.1194
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0138 0.0261 0.0276
Brugia malayi Cation transporter family protein 0.0036 0.0022 0.0024
Echinococcus granulosus glycine receptor subunit alpha 1 0.0036 0.0022 0.0022
Echinococcus granulosus sodium and chloride dependent glycine 0.0048 0.0049 0.0049
Brugia malayi hypothetical protein 0.0041 0.0033 0.0036
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0047 0.1291
Loa Loa (eye worm) hypothetical protein 0.0079 0.0122 0.0126
Loa Loa (eye worm) carboxylesterase 0.0068 0.0097 0.01
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0102 0.0176 0.0185
Brugia malayi steroid hormone receptor 0.0138 0.0261 0.0281
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0534 0.1194 0.1194
Schistosoma mansoni pyruvate kinase 0.007 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0053 0.006 0.006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0138 0.0261 0.0281
Echinococcus granulosus thioredoxin glutathione reductase 0.0079 0.0122 0.0122
Schistosoma mansoni adenoreceptor 0.0534 0.1194 0.1194
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0066 0.0071
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0042 0.0035 0.0079
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0592 0.2036
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0019 0.0019
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0053 0.0061 0.0355
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.1327 0.3064 0.3307
Toxoplasma gondii hypothetical protein 0.0037 0.0023 0.0619
Onchocerca volvulus 0.0534 0.1194 0.5036
Brugia malayi hypothetical protein 0.0534 0.1194 0.1289
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Trypanosoma brucei trypanothione reductase 0.0078 0.012 0.0129
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0138 0.0261 0.0261
Leishmania major GTP-binding protein, putative 0.0044 0.0039 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0138 0.0261 0.0276
Entamoeba histolytica hypothetical protein 0.0118 0.0215 0.0645
Onchocerca volvulus 0.0041 0.0033 0.0046
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0036 0.0022 0.0022
Echinococcus multilocularis lamin 0.0117 0.0213 0.0213
Schistosoma mansoni nAChR subunit 0.0036 0.0022 0.0022
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.0069 0.0069
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0245 0.0514 0.055
Schistosoma mansoni hypothetical protein 0.1349 0.3116 0.3116
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0122 0.3317
Echinococcus multilocularis neuropeptide Y receptor 0.0534 0.1194 0.1194
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.0122 0.027
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0138 0.0261 0.0281
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0065 0.0089 0.0089
Plasmodium vivax potassium channel, putative 0.0063 0.0084 0.2299
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0049 0.1322
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0111 0.0197 0.5379
Echinococcus granulosus flap endonuclease 1 0.0057 0.0071 0.0071
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0027 0.0029
Brugia malayi AKH receptor 0.0534 0.1194 0.1289
Echinococcus multilocularis small conductance calcium activated potassium 0.1349 0.3116 0.3116
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0019 0.0065
Brugia malayi AMP-binding enzyme family protein 0.0053 0.0061 0.0066
Brugia malayi hypothetical protein 0.0534 0.1194 0.1289
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0534 0.1194 0.1194
Toxoplasma gondii cytochrome p450 superfamily protein 0.0042 0.0035 0.0967
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Echinococcus multilocularis allatostatin A receptor 0.0534 0.1194 0.1194
Echinococcus granulosus Smad4 0.0053 0.006 0.006
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0063 0.0084 0.0091
Echinococcus granulosus carboxylesterase 5A 0.0404 0.0888 0.0888
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.0061 0.0061
Plasmodium falciparum glutathione reductase 0.0078 0.012 0.3269
Brugia malayi nuclear receptor NHR-88 0.0065 0.0089 0.0096
Schistosoma mansoni calcium-activated potassium channel 0.1349 0.3116 0.3116
Brugia malayi Serotonin receptor 0.0534 0.1194 0.1289
Toxoplasma gondii histone lysine methyltransferase SET1 0.0124 0.0229 0.6231
Onchocerca volvulus 0.0091 0.0151 0.0555
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0061 0.1655
Schistosoma mansoni nAChR subunit 0.0036 0.0022 0.0022
Onchocerca volvulus 0.0068 0.0097 0.0322
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0042 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.006 0.0077 0.0078
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0308 0.0308
Brugia malayi hypothetical protein 0.0041 0.0033 0.0036
Loa Loa (eye worm) hypothetical protein 0.0175 0.0348 0.0371
Schistosoma mansoni hypothetical protein 0.0534 0.1194 0.1194
Echinococcus granulosus biogenic amine 5HT receptor 0.094 0.2152 0.2152
Mycobacterium ulcerans hypothetical protein 0.0053 0.0061 0.0303
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0592 0.2036
Schistosoma mansoni amine GPCR 0.0534 0.1194 0.1194
Onchocerca volvulus 0.0068 0.0097 0.0322
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0534 0.1194 0.1284
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.0069 0.1883
Brugia malayi Thioredoxin reductase 0.0078 0.012 0.0129
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0178 0.0356 0.1108
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0197 0.0402 0.0893
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0122 0.0418
Onchocerca volvulus 0.0063 0.0084 0.0267
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0033 0.0033
Echinococcus granulosus tm gpcr rhodopsin 0.0534 0.1194 0.1194
Entamoeba histolytica hypothetical protein 0.0118 0.0215 0.0645
Echinococcus multilocularis neuropeptide receptor 0.0534 0.1194 0.1194
Schistosoma mansoni lozenge 0.0118 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0048 0.0049 0.0047
Schistosoma mansoni calcium-activated potassium channel 0.0063 0.0084 0.0084
Mycobacterium tuberculosis Probable oxidoreductase 0.0197 0.0402 0.0893
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Onchocerca volvulus 0.0079 0.0122 0.0427
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Trypanosoma cruzi C-14 sterol reductase, putative 0.0046 0.0045 0.0049
Brugia malayi hypothetical protein 0.0065 0.0089 0.0096
Echinococcus granulosus lamin dm0 0.0117 0.0213 0.0213
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0308 0.0328
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0042 0.0035 0.0177
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0019 0.0065
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0177 0.0355 0.0355
Echinococcus multilocularis dihydrofolate reductase 0.0053 0.0061 0.0061
Loa Loa (eye worm) TYRA-2 protein 0.0534 0.1194 0.1284
Mycobacterium ulcerans hypothetical protein 0.0079 0.0122 0.0606
Mycobacterium tuberculosis Probable integral membrane protein 0.0037 0.0023 0.005
Schistosoma mansoni calcium-activated potassium channel 0.0063 0.0084 0.0084
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0034 0.0016 0.0017
Loa Loa (eye worm) cytochrome P450 family protein 0.0079 0.0124 0.0128
Echinococcus multilocularis potassium channel subfamily K 8 0.0063 0.0084 0.0084
Brugia malayi beta-lactamase 0.0079 0.0122 0.0131
Loa Loa (eye worm) LGC-31 protein 0.0036 0.0022 0.0019
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0125 0.0232 0.0232
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0534 0.1194 0.1194
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0245 0.0514 0.0514
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0042 0.0035 0.0177
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0017 0.0076
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0115 0.0207 0.0207
Brugia malayi jmjC domain containing protein 0.0064 0.0088 0.0095
Schistosoma mansoni peptidase Clp (S14 family) 0.0085 0.0137 0.0137
Schistosoma mansoni retinoic acid receptor RXR 0.1635 0.3789 0.3789
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0033 0.0033
Echinococcus multilocularis dna polymerase eta 0.0049 0.0053 0.0053
Brugia malayi Cation transporter family protein 0.0036 0.0022 0.0024
Echinococcus multilocularis somatostatin receptor 0.0534 0.1194 0.1194
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0073 0.0109 0.0117
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0138 0.0261 0.0261
Loa Loa (eye worm) TAR-binding protein 0.007 0.0101 0.0104
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.016 0.0314 0.0314
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0014 0.0014
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0078 0.0121 0.0125
Echinococcus multilocularis 0.0042 0.0035 0.0035
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0036 0.0022 0.0024
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1771 0.4111 0.4111
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0138 0.0261 0.0276
Echinococcus multilocularis orexin receptor type 2 0.0534 0.1194 0.1194
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0065 0.0089 0.0089
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0308 0.0308
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0036 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.0039 0.0029 0.0026
Plasmodium vivax flap endonuclease 1, putative 0.0057 0.0071 0.1935
Loa Loa (eye worm) CYP4Cod1 0.0079 0.0124 0.0128
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0042 0.0035 0.0079
Echinococcus multilocularis muscleblind protein 0.0175 0.0348 0.0348
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0033 0.0033
Plasmodium vivax pyruvate kinase, putative 0.007 0.0101 0.2751
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0138 0.0261 0.0261
Echinococcus multilocularis neuropeptides capa receptor 0.0534 0.1194 0.1194
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.007 0.0101 0.0224
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0122 0.0131
Loa Loa (eye worm) hypothetical protein 0.0943 0.2158 0.2326
Loa Loa (eye worm) hypothetical protein 0.0257 0.0542 0.0581
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0036 0.0022 0.0022
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0035 0.002 0.0043
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1552 0.3596 0.3596
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0138 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Schistosoma mansoni hypothetical protein 0.0534 0.1194 0.1194
Echinococcus granulosus rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.016 0.0314 0.0314
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0019 0.0065
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0036 0.0022 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.2487 0.5798 0.6257
Brugia malayi AMP-binding enzyme family protein 0.0053 0.0061 0.0066
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0088 0.0144 0.015
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.1327 0.3064 0.3307
Echinococcus multilocularis calcium activated potassium channel variant 0.0063 0.0084 0.0084
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0088 0.0144 0.0144
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0534 0.1194 0.5036
Echinococcus granulosus p2X purinoceptor 4 0.0069 0.01 0.01
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0036 0.0022 0.0022
Toxoplasma gondii hypothetical protein 0.0048 0.0049 0.1322
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0049 0.0052
Mycobacterium tuberculosis Hypothetical protein 0.0062 0.0082 0.0182
Trypanosoma cruzi hypothetical protein, conserved 0.0063 0.0084 0.0091
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0061 0.1655
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.0061 0.0138
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.013 0.0242 0.0538
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0056 0.0068 0.0151
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0135 0.0135
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0534 0.1194 0.1194
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0027 0.0134
Echinococcus granulosus glycine receptor subunit alpha 1 0.0036 0.0022 0.0022
Echinococcus multilocularis pyruvate kinase 0.0055 0.0066 0.0066
Schistosoma mansoni P2X receptor subunit 0.0069 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0061 0.0081 0.0082
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0078 0.012 0.0267
Plasmodium vivax potassium channel, putative 0.0063 0.0084 0.2299
Loa Loa (eye worm) Smad1 0.0053 0.006 0.006
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0042 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Loa Loa (eye worm) calcium channel 0.0125 0.0232 0.0245
Echinococcus multilocularis survival motor neuron protein 1 0.0269 0.0571 0.0571
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0036 0.0022 0.0022
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0078 0.0121 0.0416
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0105 0.0183 0.0198
Loa Loa (eye worm) hypothetical protein 0.0073 0.0108 0.0111
Onchocerca volvulus 0.0534 0.1194 0.5036
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.0061 0.0303
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0036 0.0022 0.0019
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0041 0.0033 0.003
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Echinococcus multilocularis RUN 0.0041 0.0033 0.0033
Chlamydia trachomatis recombinase RecA 0.0118 0.0214 1
Loa Loa (eye worm) hypothetical protein 0.028 0.0597 0.0639
Loa Loa (eye worm) hypothetical protein 0.0178 0.0356 0.0379
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0049 0.0049
Echinococcus granulosus pyruvate kinase 0.0036 0.0021 0.0021
Echinococcus multilocularis neuroligin 0.0068 0.0097 0.0097
Brugia malayi Carboxylesterase family protein 0.0068 0.0097 0.0105
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0135 0.0146
Schistosoma mansoni alpha-glucosidase 0.0136 0.0256 0.0256
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0073 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0138 0.0261 0.0281
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0065 0.0089 0.0089
Schistosoma mansoni sodium-dependent amino acid transporter 0.0048 0.0049 0.0049
Brugia malayi hypothetical protein 0.1046 0.2403 0.2594
Mycobacterium tuberculosis Probable dehydrogenase 0.0178 0.0355 0.0789
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0063 0.0084 0.0091
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0534 0.1194 0.1289
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0063 0.0084 0.0091
Loa Loa (eye worm) hypothetical protein 0.028 0.0597 0.0639
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0057 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0534 0.1194 0.1284
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Loa Loa (eye worm) hypothetical protein 0.0091 0.0151 0.0158
Echinococcus granulosus Nuclear hormone receptor HR96 0.0065 0.0089 0.0089
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0616 0.1389 0.3086
Loa Loa (eye worm) hypothetical protein 0.0404 0.0888 0.0953
Schistosoma mansoni biogenic amine receptor 0.0534 0.1194 0.1194
Onchocerca volvulus 0.0534 0.1194 0.5036
Loa Loa (eye worm) hypothetical protein 0.0138 0.0261 0.0276
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0048 0.0049 0.0047
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0078 0.0121 0.0335
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0036 0.0022 0.0022
Leishmania major trypanothione reductase 0.0078 0.012 0.0129
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0039 0.0042
Brugia malayi hypothetical protein 0.0073 0.0108 0.0116
Schistosoma mansoni amine GPCR 0.0534 0.1194 0.1194
Brugia malayi hypothetical protein 0.0034 0.0017 0.0018
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0534 0.1194 0.1194
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0534 0.1194 0.1194
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0138 0.0261 0.0276
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0049 0.0049
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0065 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.1046 0.2403 0.259
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0057 0.007 0.007
Schistosoma mansoni gliotactin 0.0068 0.0097 0.0097
Trypanosoma cruzi sterol C-24 reductase, putative 0.0046 0.0045 0.0049
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0042 0.0035 0.0177
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0076 0.208
Schistosoma mansoni acetylcholinesterase 0.0068 0.0097 0.0097
Brugia malayi PAS domain containing protein 0.0053 0.0061 0.0066
Mycobacterium ulcerans ion transport protein 0.0063 0.0084 0.042
Brugia malayi putative neuropeptide receptor NPR1 0.0534 0.1194 0.1289
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0119 0.0217 0.0235
Echinococcus multilocularis fmrfamide receptor 0.0534 0.1194 0.1194
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0014 0.0014
Echinococcus multilocularis thymidylate synthase 0.013 0.0242 0.0242
Brugia malayi Smad1 0.0053 0.006 0.0065
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0036 0.0022 0.0022
Leishmania major cytochrome p450-like protein 0.0079 0.0124 0.0133
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.0122 0.0122
Brugia malayi MH1 domain containing protein 0.0053 0.006 0.0065
Echinococcus multilocularis G-protein coupled receptor, putative 0.0534 0.1194 0.1194
Loa Loa (eye worm) pyruvate kinase-PB 0.0049 0.0051 0.005
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0044 0.0039 0.0042
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.0122 0.027
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0063 0.0084 0.0091
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Brugia malayi hypothetical protein 0.0534 0.1194 0.1289
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0037 0.0023 0.005
Echinococcus multilocularis potassium channel subfamily K 0.0063 0.0084 0.0084
Schistosoma mansoni sodium/chloride dependent transporter 0.028 0.0597 0.0597
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0042 0.0035 0.0177
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0125 0.0232 0.025
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1261 0.2909 1
Schistosoma mansoni opsin-like receptor 0.0534 0.1194 0.1194
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0138 0.0261 0.0281
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0038 0.0063
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0111 0.0197 0.0678
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Echinococcus granulosus fmrfamide receptor 0.0534 0.1194 0.1194
Chlamydia trachomatis dihydrofolate reductase 0.0053 0.0061 0.2859
Brugia malayi nuclear receptor RXR 0.0065 0.0089 0.0096
Echinococcus granulosus g protein coupled receptor 0.0534 0.1194 0.1194
Brugia malayi Intermediate filament tail domain containing protein 0.0117 0.0213 0.0229
Schistosoma mansoni tar DNA-binding protein 0.007 0.0101 0.0101
Onchocerca volvulus 0.0063 0.0084 0.0267
Loa Loa (eye worm) hypothetical protein 0.1349 0.3116 0.336
Onchocerca volvulus 0.0534 0.1194 0.5036
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0042 0.0035 0.0079
Schistosoma mansoni neuropeptide receptor 0.0534 0.1194 0.1194
Schistosoma mansoni twik family of potassium channels-related 0.0063 0.0084 0.0084
Brugia malayi intermediate filament protein 0.0117 0.0213 0.0229
Trypanosoma cruzi cytochrome P450, putative 0.0079 0.0124 0.0133
Mycobacterium leprae Probable lipase LipE 0.0079 0.0122 0.0745
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0119 0.0217 0.1081
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0036 0.0022 0.0019
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0119 0.0217 0.0217
Schistosoma mansoni pyruvate kinase 0.007 0.0101 0.0101
Plasmodium vivax SET domain protein, putative 0.013 0.0243 0.6627
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0053 0.006 0.006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1261 0.2909 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0534 0.1194 0.1289
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0068 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0073 0.0108 0.0111
Brugia malayi G protein-coupled receptor 0.0534 0.1194 0.1289
Trypanosoma brucei pyruvate kinase 1 0.007 0.0101 0.0109
Onchocerca volvulus 0.0063 0.0084 0.0267
Echinococcus multilocularis neuropeptide Y receptor 0.0534 0.1194 0.1194
Brugia malayi G-protein coupled receptor 0.0534 0.1194 0.1289
Brugia malayi beta-lactamase family protein 0.0079 0.0122 0.0131
Echinococcus granulosus potassium channel subfamily K 0.0063 0.0084 0.0084
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0033 0.0897
Onchocerca volvulus 0.0457 0.1014 0.4264
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0033 0.0033
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0064 0.0088 0.0088
Echinococcus multilocularis pyruvate kinase 0.007 0.0101 0.0101
Onchocerca volvulus 0.0534 0.1194 0.5036
Echinococcus granulosus serotonin transporter 0.028 0.0597 0.0597
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Brugia malayi hypothetical protein 0.0257 0.0542 0.0586
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0091 0.0151 0.0151
Brugia malayi Carboxylesterase family protein 0.0068 0.0097 0.0105
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0534 0.1194 0.1194
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0061 0.0066
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0037 0.0023 0.005
Loa Loa (eye worm) hypothetical protein 0.0117 0.0213 0.0224
Echinococcus multilocularis sodium and chloride dependent glycine 0.0048 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0041 0.0033 0.003
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0042 0.0035 0.0038
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Schistosoma mansoni hypothetical protein 0.147 0.3401 0.3401
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0073 0.0108 0.0111
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Loa Loa (eye worm) carboxylesterase 0.0068 0.0097 0.01
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0088 0.0144 0.0155
Echinococcus multilocularis pyruvate kinase 0.0036 0.0021 0.0021
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0124 0.0229 0.0229
Echinococcus granulosus alpha 1A adrenergic receptor 0.0534 0.1194 0.1194
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0065 0.0089 0.0096
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1261 0.2909 0.9494
Brugia malayi nuclear receptor RXR 0.0073 0.0108 0.0116
Echinococcus granulosus neuropeptide receptor 0.0534 0.1194 0.1194
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0036 0.0022 0.0022
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0069 0.0075
Loa Loa (eye worm) MH2 domain-containing protein 0.0772 0.1756 0.1891
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0502 0.1121 0.249
Echinococcus multilocularis nAChR subunit 0.0036 0.0022 0.0022
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0065 0.0089 0.0288
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0534 0.1194 0.1194
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0061 0.1655
Schistosoma mansoni glutaminase 0.088 0.201 0.201
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0042 0.0035 0.0079
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0042 0.0035 0.0079
Echinococcus granulosus GPCR family 2 0.0033 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0077 0.0119 0.0123
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.0069 0.0069
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0042 0.0035 0.0177
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0057 0.0071 0.0077
Loa Loa (eye worm) hypothetical protein 0.3957 0.9263 1
Echinococcus granulosus CAAX prenyl protease 2 0.0177 0.0355 0.0355
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0042 0.0035 0.0177
Brugia malayi hypothetical protein 0.0063 0.0084 0.0091
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0049 0.0049
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0102 0.0176 0.0605
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0534 0.1194 0.1194
Brugia malayi MAP kinase sur-1 0.0056 0.0069 0.0075
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0027 0.126
Schistosoma mansoni amine GPCR 0.0534 0.1194 0.1194
Schistosoma mansoni hypothetical protein 0.0041 0.0033 0.0033
Echinococcus granulosus peptidase Clp S14 family 0.0056 0.0068 0.0068
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.001 0.001
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0138 0.0261 0.0261
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0042 0.0035 0.0038
Echinococcus granulosus lamin b receptor 0.0046 0.0045 0.0045
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0042 0.0035 0.0177
Brugia malayi ORL1-like opioid receptor 0.0534 0.1194 0.1289
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0036 0.0022 0.0024
Echinococcus multilocularis nuclear receptor nhr 48 0.0065 0.0089 0.0089
Echinococcus granulosus pyruvate kinase 0.007 0.0101 0.0101
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0534 0.1194 0.1194
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0634 0.143 0.1539
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0367 0.1261
Brugia malayi conserved hypotetical protein 0.0065 0.0089 0.0096
Echinococcus granulosus muscleblind protein 0.0175 0.0348 0.0348
Loa Loa (eye worm) hypothetical protein 0.0039 0.0029 0.0026
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0031 0.001 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.013 0.0243 0.0243
Schistosoma mansoni hypothetical protein 0.0033 0.0014 0.0014
Echinococcus granulosus lysine specific demethylase 5A 0.0068 0.0096 0.0096
Trypanosoma cruzi ion transport protein, putative 0.0063 0.0084 0.0091
Echinococcus granulosus Nuclear hormone receptor HR96 0.0065 0.0089 0.0089
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0014 0.0014
Echinococcus granulosus glycine receptor subunit alpha 1 0.0036 0.0022 0.0022
Brugia malayi hypothetical protein 0.0943 0.2158 0.233
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0068 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Echinococcus granulosus FTZ F1 alpha 0.0138 0.0261 0.0261
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0616 0.1389 0.691
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0138 0.0261 0.0276
Mycobacterium tuberculosis Conserved protein 0.0079 0.0122 0.027
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0367 0.1261
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0534 0.1194 0.1284
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Echinococcus granulosus smad 0.0053 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0053 0.0061 0.006
Echinococcus granulosus transcription factor Dp 1 0.0768 0.1747 0.1747
Echinococcus granulosus peptide allatostatin:somatostatin 0.0534 0.1194 0.1194
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0036 0.0022 0.0022
Echinococcus granulosus pyruvate kinase 0.0036 0.0021 0.0021
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0033 0.0033
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0027 0.0027
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0579 0.1302 0.1401
Brugia malayi Carboxylesterase family protein 0.0068 0.0097 0.0105
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0278 0.0592 0.0635
Loa Loa (eye worm) hypothetical protein 0.0049 0.0053 0.0052
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0057 0.0071 0.0077
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0036 0.0022 0.0022
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0178 0.0355 0.2244
Brugia malayi tailless protein 0.0065 0.0089 0.0096
Onchocerca volvulus 0.0063 0.0084 0.0267
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.0069 0.0069
Schistosoma mansoni smad1 5 8 and 0.0053 0.006 0.006
Brugia malayi hypothetical protein 0.0534 0.1194 0.1289
Echinococcus granulosus lamin 0.0117 0.0213 0.0213
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0183 0.0367 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0056 0.0068 0.0401
Echinococcus multilocularis CAAX prenyl protease 2 0.0177 0.0355 0.0355
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0036 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.0069 0.0075
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0073 0.0108 0.0108
Loa Loa (eye worm) thymidylate synthase 0.013 0.0242 0.0256
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0019 0.0015
Loa Loa (eye worm) hypothetical protein 0.0048 0.0049 0.0047
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0036 0.0022 0.0022
Echinococcus multilocularis p2X purinoceptor 4 0.0069 0.01 0.01
Echinococcus multilocularis tar DNA binding protein 0.007 0.0101 0.0101
Schistosoma mansoni nuclear receptor 0.0065 0.0089 0.0089
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0534 0.1194 0.1284
Echinococcus multilocularis dnaJ subfamily B 0.0867 0.198 0.198
Mycobacterium ulcerans hypothetical protein 0.0037 0.0023 0.0113
Brugia malayi Nuclear hormone receptor E75 0.0065 0.0089 0.0096
Brugia malayi MH2 domain containing protein 0.0772 0.1756 0.1895
Onchocerca volvulus 0.0053 0.0061 0.0166
Brugia malayi TAR-binding protein 0.007 0.0101 0.0109
Schistosoma mansoni twik family of potassium channels-related 0.0063 0.0084 0.0084
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0137 0.026 0.0894
Echinococcus multilocularis cpg binding protein 0.0064 0.0088 0.0088
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0197 0.0402 0.0893
Echinococcus granulosus intermediate filament protein 0.0117 0.0213 0.0213
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.039 0.1341
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0616 0.1389 0.888
Schistosoma mansoni RAR-like nuclear receptor 0.0138 0.0261 0.0261
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0078 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Onchocerca volvulus 0.0534 0.1194 0.5036
Trypanosoma brucei C-8 sterol isomerase, putative 0.3957 0.9263 1
Echinococcus granulosus tm gpcr rhodopsin 0.1552 0.3596 0.3596
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0138 0.0261 0.0261
Entamoeba histolytica pyruvate kinase, putative 0.0049 0.0051 0.0106
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0135 0.0135
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0078 0.0121 0.5657
Echinococcus granulosus dihydrofolate reductase 0.0053 0.0061 0.0061
Trichomonas vaginalis ap endonuclease, putative 0.0078 0.0121 0.0416
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.0069 0.0075
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0023 0.005
Mycobacterium ulcerans hypothetical protein 0.0037 0.0023 0.0113
Brugia malayi glutathione reductase 0.0078 0.012 0.0129
Plasmodium vivax thioredoxin reductase, putative 0.0078 0.012 0.3269
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0105 0.0183 0.0192
Toxoplasma gondii ion channel protein 0.0063 0.0084 0.2299
Schistosoma mansoni hypothetical protein 0.0055 0.0066 0.0066
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0036 0.0022 0.0024
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.0122 0.0131
Brugia malayi hypoxia-induced factor 1 0.0164 0.0323 0.0349
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0014 0.001
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0014 0.0016
Brugia malayi glucose-6-phosphate dehydrogenase 0.0102 0.0176 0.019
Loa Loa (eye worm) hypothetical protein 0.0079 0.0122 0.0126
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0063 0.0084 0.0215
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0049 0.0049
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0078 0.0121 0.3295
Schistosoma mansoni dihydrofolate reductase 0.0053 0.0061 0.0061
Echinococcus granulosus small conductance calcium activated potassium 0.1349 0.3116 0.3116
Entamoeba histolytica CAAX prenyl protease family 0.0177 0.0355 0.1103
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0138 0.0261 0.0281
Loa Loa (eye worm) voltage-dependent calcium channel 0.0073 0.0109 0.0112
Loa Loa (eye worm) hypothetical protein 0.0073 0.0108 0.0111
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0024 0.0054
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0111 0.0197 0.0678
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Schistosoma mansoni alpha glucosidase 0.0035 0.0019 0.0019
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.0122 0.027
Echinococcus granulosus 7TM GPCR rhodopsin 0.0534 0.1194 0.1194
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0534 0.1194 0.1194
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0053 0.0061 0.0356
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0027 0.0093
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Onchocerca volvulus 0.0534 0.1194 0.5036
Brugia malayi larval opioid receptor 0.0534 0.1194 0.1289
Loa Loa (eye worm) hypothetical protein 0.0068 0.0097 0.01
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Loa Loa (eye worm) G-protein coupled receptor 0.0534 0.1194 0.1284
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0053 0.0061 0.0303
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0245 0.0514 0.0514
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Brugia malayi hypothetical protein 0.0534 0.1194 0.1289
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.0122 0.0122
Brugia malayi Flap endonuclease-1 0.0057 0.0071 0.0077
Schistosoma mansoni opsin-like receptor 0.0534 0.1194 0.1194
Brugia malayi follicle stimulating hormone receptor 0.0534 0.1194 0.1289
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0042 0.0035 0.0038
Schistosoma mansoni transcription factor LCR-F1 0.0118 0.0215 0.0215
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0033 0.003
Echinococcus granulosus glycine receptor subunit beta 0.0036 0.0022 0.0022
Toxoplasma gondii hypothetical protein 0.0029 0.0006 0.0154
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0036 0.0022 0.0024
Brugia malayi excitatory GABA receptor EXP-1A 0.0036 0.0022 0.0024
Echinococcus multilocularis flap endonuclease 1 0.0057 0.0071 0.0071
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0592 0.2036
Treponema pallidum hypothetical protein 0.0037 0.0023 0.0078
Loa Loa (eye worm) hypothetical protein 0.007 0.0101 0.0104
Echinococcus granulosus voltage dependent calcium channel 0.0125 0.0232 0.0232
Mycobacterium ulcerans beta-lactamase 0.0079 0.0122 0.0606
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0197 0.0402 0.2544
Schistosoma mansoni P2X receptor subunit 0.0069 0.01 0.01
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0367 0.1261
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.0069 0.0237
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0073 0.0108 0.0108
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0105 0.0113
Brugia malayi beta-lactamase family protein 0.0079 0.0122 0.0131
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0138 0.0261 0.1024
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0085 0.0137 0.0137
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0118 0.0215 0.0215
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0053 0.0061 0.0304
Brugia malayi Pyruvate kinase, M2 isozyme 0.007 0.0101 0.0109
Loa Loa (eye worm) hypothetical protein 0.0073 0.0108 0.0111
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.0137 0.0684
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.1562 0.3618 0.3618
Loa Loa (eye worm) hypothetical protein 0.0048 0.0049 0.0047
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0062 0.0082 0.0088
Echinococcus multilocularis pyruvate kinase 0.0036 0.0021 0.0021
Brugia malayi Nuclear hormone receptor-like 1 0.0073 0.0108 0.0116
Brugia malayi MH2 domain containing protein 0.0053 0.006 0.0065
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Echinococcus granulosus sodium and chloride dependent glycine 0.0048 0.0049 0.0049
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0027 0.0093
Schistosoma mansoni lipoxygenase 0.0041 0.0033 0.0033
Echinococcus granulosus histone acetyltransferase KAT2B 0.0156 0.0303 0.0303
Echinococcus multilocularis serotonin transporter 0.028 0.0597 0.0597
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0076 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.039 0.1341
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0036 0.0022 0.0022
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0137 0.026 0.0894
Loa Loa (eye worm) TWK-28 protein 0.0063 0.0084 0.0086
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0177 0.0355 0.0383
Brugia malayi Cytochrome P450 family protein 0.0042 0.0035 0.0038
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0063 0.0084 0.0084
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0036 0.0022 0.0022
Echinococcus granulosus snurportin 1 0.0634 0.143 0.143
Echinococcus granulosus somatostatin receptor 0.0534 0.1194 0.1194
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0053 0.0061 0.0355
Onchocerca volvulus 0.0068 0.0097 0.0322
Brugia malayi Steroid receptor seven-up type 2 0.0138 0.0261 0.0281
Giardia lamblia Fructose-bisphosphate aldolase 0.1261 0.2909 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0039 0.0042
Onchocerca volvulus 0.0943 0.2158 0.918
Brugia malayi hypothetical protein 0.0269 0.0571 0.0616
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.0069 0.0075
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0101 0.0109
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0042 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.0039 0.0029 0.0026
Brugia malayi Trypsin family protein 0.0091 0.0151 0.0164
Schistosoma mansoni tar DNA-binding protein 0.007 0.0101 0.0101
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1936 0.4501 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0053 0.006 0.006
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0036 0.0022 0.0024
Echinococcus multilocularis carboxylesterase 5A 0.0404 0.0888 0.0888
Schistosoma mansoni voltage-gated potassium channel 0.0095 0.0161 0.0161
Brugia malayi GnHR receptor homolog 0.0534 0.1194 0.1289
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.0061 0.0066
Schistosoma mansoni rab6-interacting 0.0041 0.0033 0.0033
Trypanosoma brucei cytochrome P450, putative 0.0079 0.0124 0.0133
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0534 0.1194 0.1289
Loa Loa (eye worm) hypothetical protein 0.0048 0.0049 0.0047
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.0137 0.6428
Brugia malayi ImpB/MucB/SamB family protein 0.0049 0.0053 0.0057
Echinococcus multilocularis ecdysone induced protein 78C 0.0138 0.0261 0.0261
Loa Loa (eye worm) inositol-1 0.0038 0.0027 0.0024
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0036 0.0022 0.0024
Loa Loa (eye worm) thioredoxin reductase 0.0078 0.012 0.0124
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0065 0.0089 0.0091
Echinococcus multilocularis lysine specific demethylase 5A 0.0064 0.0088 0.0088
Echinococcus granulosus twik family of potassium channels 0.0063 0.0084 0.0084
Schistosoma mansoni inositol monophosphatase 0.0038 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0102 0.0176 0.0176
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1261 0.2909 1
Plasmodium vivax amine transporter, putative 0.0048 0.0049 0.1322
Loa Loa (eye worm) flap endonuclease-1 0.0057 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Schistosoma mansoni biogenic amine (5HT) receptor 0.094 0.2152 0.2152
Loa Loa (eye worm) solute carrier family 6 member 4 0.028 0.0597 0.0639
Echinococcus multilocularis pyruvate kinase 0.0036 0.0021 0.0021
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0017 0.0039
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0044 0.0039 0.1073
Entamoeba histolytica Flap nuclease, putative 0.0057 0.0071 0.0171
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0019 0.0065
Onchocerca volvulus Huntingtin homolog 0.0257 0.0542 0.2236
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0063 0.0084 0.0086
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.0061 0.0138
Echinococcus granulosus cpg binding protein 0.0064 0.0088 0.0088
Loa Loa (eye worm) acetyltransferase 0.016 0.0314 0.0334
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0177 0.0355 0.0378
Mycobacterium ulcerans carboxylesterase, LipT 0.0068 0.0097 0.0483
Loa Loa (eye worm) pyruvate kinase 0.007 0.0101 0.0104
Echinococcus multilocularis smad 0.0053 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0079 0.0122 0.0126
Loa Loa (eye worm) hypothetical protein 0.0059 0.0076 0.0077
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.013 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.2487 0.5798 0.6257
Trypanosoma cruzi hypothetical protein, conserved 0.0063 0.0084 0.0091
Loa Loa (eye worm) acetylcholinesterase 1 0.0404 0.0888 0.0953
Leishmania major DNA polymerase eta, putative 0.0049 0.0053 0.0057
Onchocerca volvulus 0.0065 0.0089 0.0288
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0102 0.0176 0.019
Echinococcus multilocularis para nitrobenzyl esterase 0.0068 0.0097 0.0097
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0048 0.0049 0.0049
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0125 0.0232 0.0232
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0065 0.0089 0.0089
Schistosoma mansoni hypothetical protein 0.0033 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.2022 0.4704 0.5075
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0018 0.0496
Echinococcus multilocularis Protein lozenge 0.0118 0.0215 0.0215
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0063 0.0084 0.0091
Echinococcus multilocularis musashi 0.0117 0.0213 0.0213
Brugia malayi ecdysone receptor 0.0065 0.0089 0.0096
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Mycobacterium tuberculosis Carboxylesterase LipT 0.0068 0.0097 0.0216
Echinococcus multilocularis biogenic amine (5HT) receptor 0.094 0.2152 0.2152
Brugia malayi hypothetical protein 0.0062 0.0082 0.0088
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0063 0.0084 0.0091
Onchocerca volvulus 0.0534 0.1194 0.5036
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0036 0.0022 0.0022
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0137 0.0472
Mycobacterium tuberculosis Conserved protein 0.0079 0.0122 0.027
Toxoplasma gondii ion channel protein 0.0063 0.0084 0.2299
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.0122 0.0126
Echinococcus multilocularis transcription factor Dp 1 0.0768 0.1747 0.1747
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0036 0.0022 0.0022
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0066 0.0093 0.2532
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0125 0.0232 0.0232
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.028 0.0597 0.0597
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0138 0.0261 0.0261
Echinococcus granulosus BC026374 protein S09 family 0.0068 0.0097 0.0097
Brugia malayi hypothetical protein 0.0118 0.0215 0.0232
Schistosoma mansoni jumonji/arid domain-containing protein 0.0068 0.0096 0.0096
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0534 0.1194 0.1194
Schistosoma mansoni survival motor neuron protein 0.0055 0.0066 0.0066
Schistosoma mansoni flap endonuclease-1 0.0052 0.0058 0.0058
Loa Loa (eye worm) glutathione reductase 0.0078 0.012 0.0124
Brugia malayi MH1 domain containing protein 0.0029 0.0005 0.0005
Onchocerca volvulus 0.0534 0.1194 0.5036
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.0069 0.0069
Echinococcus multilocularis potassium channel subfamily K 8 0.0063 0.0084 0.0084
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0117 0.0213 0.0224
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0138 0.0261 0.0261
Brugia malayi Cytochrome P450 family protein 0.0079 0.0124 0.0133
Trypanosoma brucei C-14 sterol reductase, putative 0.0046 0.0045 0.0049
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0245 0.0514 0.0555
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0029 0.0029
Brugia malayi hypothetical protein 0.0053 0.0061 0.0066
Echinococcus multilocularis sex peptide receptor 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Loa Loa (eye worm) hypothetical protein 0.0404 0.0888 0.0953
Loa Loa (eye worm) hypothetical protein 0.028 0.0597 0.0639
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.1327 0.3064 0.3307
Echinococcus granulosus mothers against decapentaplegic 5 0.0053 0.006 0.006
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0044 0.0039 0.1073
Echinococcus granulosus glycine receptor subunit beta 0.0036 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0646 0.1458 0.157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0138 0.0261 0.0276
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0036 0.0022 0.0024
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0063 0.0084 0.0091
Brugia malayi nuclear hormone receptor 0.0138 0.0261 0.0281
Leishmania major hypothetical protein, conserved 0.0079 0.0122 0.0131
Giardia lamblia DNA repair protein RAD52 0.0397 0.0873 0.3002
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0063 0.0084 0.0091
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0039 0.0029 0.0147
Loa Loa (eye worm) hypothetical protein 0.0138 0.0261 0.0276
Brugia malayi hypothetical protein 0.0048 0.0049 0.0052
Echinococcus granulosus serotonin receptor 0.0534 0.1194 0.1194
Onchocerca volvulus 0.0061 0.008 0.0248
Brugia malayi hypothetical protein 0.0534 0.1194 0.1289
Schistosoma mansoni myosin xvIII 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0269 0.0571 0.0611
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Toxoplasma gondii thioredoxin reductase 0.0078 0.012 0.3269
Brugia malayi ecdysteroid receptor 0.0138 0.0261 0.0281
Loa Loa (eye worm) hypothetical protein 0.0068 0.0097 0.01
Echinococcus granulosus cytochrome P450 2K1 0.0042 0.0035 0.0035
Onchocerca volvulus 0.1024 0.2349 1
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0069 0.0237
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0138 0.0261 0.0261
Schistosoma mansoni hypothetical protein 0.0534 0.1194 0.1194
Loa Loa (eye worm) neuropeptide F receptor 0.0534 0.1194 0.1284
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0036 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0036 0.0022 0.0024
Treponema pallidum recombinase A 0.0118 0.0214 0.0735
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0063 0.0084 0.0091
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0042 0.0035 0.0177
Echinococcus granulosus acetylcholinesterase 0.0404 0.0888 0.0888
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0122 0.0131
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0183 0.0367 1
Leishmania major cytochrome p450-like protein 0.0042 0.0035 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0053 0.0061 0.0066
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0138 0.0261 0.0261
Loa Loa (eye worm) cytochrome P450 0.0042 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0048 0.0049 0.0047
Echinococcus granulosus neuroligin 0.0068 0.0097 0.0097
Trichomonas vaginalis ran, putative 0.0044 0.0039 0.0135
Schistosoma mansoni voltage-gated cation channel 0.0125 0.0232 0.0232
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1261 0.2909 1
Loa Loa (eye worm) steroid hormone receptor 0.0138 0.0261 0.0276
Schistosoma mansoni P2X receptor subunit 0.0069 0.01 0.01
Brugia malayi dihydrofolate reductase family protein 0.0053 0.0061 0.0066
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Brugia malayi hypothetical protein 0.0065 0.0089 0.0096
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Echinococcus granulosus para nitrobenzyl esterase 0.0068 0.0097 0.0097
Leishmania major pyruvate kinase 0.007 0.0101 0.0109
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0592 0.2036
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Schistosoma mansoni intermediate filament proteins 0.0117 0.0213 0.0213
Onchocerca volvulus 0.0079 0.0122 0.0427
Echinococcus granulosus sex peptide receptor 0.0534 0.1194 0.1194
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0063 0.0084 0.0084
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0048 0.0049 0.227
Mycobacterium leprae putative cytochrome p450 0.0042 0.0035 0.0192
Schistosoma mansoni nuclear receptor nhr-48 0.0065 0.0089 0.0089
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0245 0.0514 0.0514
Echinococcus multilocularis BC026374 protein (S09 family) 0.0068 0.0097 0.0097
Entamoeba histolytica hypothetical protein 0.0048 0.005 0.0102
Schistosoma mansoni hypothetical protein 0.0033 0.0014 0.0014
Toxoplasma gondii hypothetical protein 0.0037 0.0023 0.0619
Brugia malayi thymidylate synthase 0.013 0.0242 0.0261
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Schistosoma mansoni importin beta-1 0.0059 0.0076 0.0076
Schistosoma mansoni histamine h1 receptor 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Schistosoma mansoni hypothetical protein 0.0534 0.1194 0.1194
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0138 0.0261 0.0261
Onchocerca volvulus Huntingtin homolog 0.0257 0.0542 0.2236
Brugia malayi Probable ClpP-like protease 0.0085 0.0137 0.0148
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0085 0.0137 0.3744
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0042 0.0035 0.0177
Schistosoma mansoni loxhd1 0.0041 0.0033 0.0033
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0308 0.0333
Loa Loa (eye worm) G-protein coupled receptor 0.0534 0.1194 0.1284
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.1327 0.3064 0.3064
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0534 0.1194 0.1194
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0006 0.0019
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0048 0.0049 0.0049
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0066 0.0093 0.0462
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0178 0.0355 0.0789
Plasmodium vivax importin-beta 2, putative 0.0059 0.0076 0.208
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0057 0.0071 0.0077
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0138 0.0261 0.0276
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0085 0.0137 0.0846
Loa Loa (eye worm) pyruvate kinase 0.007 0.0101 0.0104
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.0061 0.0066
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0177 0.0355 0.0383
Brugia malayi cytoplasmic intermediate filament protein 0.0063 0.0084 0.0091
Loa Loa (eye worm) hypothetical protein 0.0057 0.007 0.007
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0027 0.0734
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0064 0.0088 0.0088
Brugia malayi Dihydrofolate reductase 0.0053 0.0061 0.0066
Schistosoma mansoni ran 0.0044 0.0039 0.0039
Brugia malayi Cytochrome P450 family protein 0.0079 0.0124 0.0133
Onchocerca volvulus 0.0063 0.0084 0.0267
Onchocerca volvulus 0.0048 0.0049 0.0113
Leishmania major C-8 sterol isomerase-like protein 0.3957 0.9263 1
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0033 0.0897
Onchocerca volvulus Protein ultraspiracle homolog 0.0138 0.0261 0.1024
Echinococcus granulosus survival motor neuron protein 1 0.0269 0.0571 0.0571
Echinococcus multilocularis glycine receptor subunit beta 0.0036 0.0022 0.0022
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.0122 0.0606
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0019 0.0515
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1261 0.2909 1
Schistosoma mansoni jumonji domain containing protein 0.0064 0.0088 0.0088
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.0137 0.3744
Schistosoma mansoni twik family of potassium channels-related 0.0063 0.0084 0.0084
Schistosoma mansoni Smad4 0.0053 0.006 0.006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0068 0.0097 0.0097
Echinococcus multilocularis thyroid hormone receptor alpha 0.0138 0.0261 0.0261
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.1327 0.3064 0.3307
Onchocerca volvulus Neuropeptide F receptor homolog 0.0534 0.1194 0.5036
Echinococcus granulosus dnaJ subfamily B 0.0867 0.198 0.198
Loa Loa (eye worm) carboxylesterase 0.0404 0.0888 0.0953
Giardia lamblia Hypothetical protein 0.0063 0.0084 0.029
Toxoplasma gondii hypothetical protein 0.0048 0.0049 0.1322
Echinococcus multilocularis rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Brugia malayi Dopamine receptor 0.0534 0.1194 0.1289
Echinococcus granulosus rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0534 0.1194 0.1194
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0534 0.1194 0.1194
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0061 0.0066
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0089 0.0089
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.0122 0.027
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0042 0.0035 0.0079
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0122 0.0418
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0019 0.0065
Brugia malayi CXXC zinc finger family protein 0.0061 0.008 0.0086
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Onchocerca volvulus 0.0068 0.0097 0.0322
Plasmodium falciparum acyl-CoA synthetase 0.0039 0.0029 0.0803
Plasmodium vivax protease, putative 0.0037 0.0023 0.0619
Schistosoma mansoni smad 0.0053 0.006 0.006
Echinococcus multilocularis geminin 0.147 0.3401 0.3401
Onchocerca volvulus 0.0117 0.0213 0.0818
Onchocerca volvulus 0.0041 0.0033 0.0046
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0063 0.0084 0.0084
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0042 0.0035 0.0177
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0057 0.0071 0.1935
Echinococcus multilocularis p2X purinoceptor 4 0.0069 0.01 0.01
Echinococcus multilocularis neuropeptide FF receptor 2 0.0534 0.1194 0.1194
Trypanosoma cruzi pyruvate kinase 2, putative 0.007 0.0101 0.0109
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0534 0.1194 0.1194
Echinococcus granulosus orexin receptor type 2 0.0534 0.1194 0.1194
Echinococcus multilocularis mothers against decapentaplegic 5 0.0053 0.006 0.006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0024 0.0054
Brugia malayi G protein-coupled receptor F59B2.13 0.0534 0.1194 0.1289
Echinococcus multilocularis snurportin 1 0.0634 0.143 0.143
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0036 0.0022 0.0022
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0078 0.0121 0.0131
Onchocerca volvulus 0.0534 0.1194 0.5036
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0063 0.0084 0.0086
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.0069 0.0075
Loa Loa (eye worm) hypothetical protein 0.0053 0.0061 0.006
Echinococcus multilocularis dro:myosuppressin receptor 0.0534 0.1194 0.1194
Schistosoma mansoni biogenic amine receptor 0.0534 0.1194 0.1194
Echinococcus granulosus potassium channel subfamily K 8 0.0063 0.0084 0.0084
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0078 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0068 0.0097 0.01
Loa Loa (eye worm) hypothetical protein 0.0068 0.0097 0.01
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.013 0.0242 0.0242
Schistosoma mansoni polycystin 1-related 0.0041 0.0033 0.0033
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0138 0.0261 0.0261
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0063 0.0084 0.0091
Loa Loa (eye worm) hypoxia-induced factor 1 0.0164 0.0323 0.0344
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0367 0.1261
Entamoeba histolytica hypothetical protein 0.0118 0.0215 0.0645
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0138 0.0261 0.0281
Trichomonas vaginalis importin beta-1, putative 0.0048 0.005 0.0171
Echinococcus granulosus tachykinin peptides receptor 99D 0.0534 0.1194 0.1194
Schistosoma mansoni neuroligin 3 (S09 family) 0.0068 0.0097 0.0097
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0079 0.0122 0.0126
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0049 0.1322
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Brugia malayi putative neuropeptide receptor 0.0534 0.1194 0.1289
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0069 0.0069
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0308 0.0308
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0534 0.1194 0.1194
Echinococcus multilocularis voltage gated potassium channel 0.0031 0.001 0.001
Echinococcus granulosus pyruvate kinase 0.007 0.0101 0.0101
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0125 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0078 0.0121 0.0131
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0592 0.2036
Leishmania major ion transport protein-like protein 0.0063 0.0084 0.0091
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.0122 0.027
Entamoeba histolytica hypothetical protein 0.0113 0.0203 0.0605
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0063 0.0084 0.0091
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.005 0.0171
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0044 0.0039 0.0042
Echinococcus granulosus neuropeptide s receptor 0.0534 0.1194 0.1194
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0063 0.0084 0.0091
Trypanosoma cruzi trypanothione reductase, putative 0.0078 0.012 0.0129
Chlamydia trachomatis hypothetical protein 0.0037 0.0023 0.1062
Schistosoma mansoni nAChR subunit 0.0036 0.0022 0.0022
Schistosoma mansoni rab6-interacting 0.0041 0.0033 0.0033
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0049 0.0049
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0042 0.0035 0.0079
Loa Loa (eye worm) neuropeptide F receptor 0.0534 0.1194 0.1284
Echinococcus granulosus single minded 2 0.0047 0.0046 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.0061 0.0303
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0065 0.0089 0.0089
Brugia malayi RNA, U transporter 1 0.0169 0.0334 0.0361
Loa Loa (eye worm) hypothetical protein 0.0053 0.0061 0.006
Mycobacterium ulcerans transmembrane cation transporter 0.0063 0.0084 0.042
Brugia malayi hypothetical protein 0.0073 0.0108 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0082 0.0281
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0534 0.1194 0.1194
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.0069 0.0069
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0036 0.0022 0.0019
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0042 0.0035 0.0177
Loa Loa (eye worm) hypothetical protein 0.0138 0.0261 0.0276
Schistosoma mansoni alpha-glucosidase 0.0136 0.0256 0.0256
Mycobacterium leprae Conserved hypothetical protein 0.0042 0.0035 0.0192
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0019 0.0065
Plasmodium falciparum protease, putative 0.0037 0.0023 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0031 0.001 0.0006
Leishmania major calcium/potassium channel (CAKC), putative 0.0063 0.0084 0.0091
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0078 0.0121 0.3295
Schistosoma mansoni cytochrome P450 0.0042 0.0035 0.0035
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0033 0.0033
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.0137 0.6428
Brugia malayi Carboxylesterase family protein 0.0404 0.0888 0.0958
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0036 0.0022 0.0024
Onchocerca volvulus 0.0048 0.0049 0.0113
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0036 0.0022 0.0019
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Onchocerca volvulus 0.0534 0.1194 0.5036
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0053 0.0061 0.0136
Brugia malayi Nuclear hormone receptor-like 1 0.0073 0.0108 0.0116
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0101 0.0104
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0063 0.0084 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0138 0.0261 0.0281
Schistosoma mansoni lamin 0.0117 0.0213 0.0213
Echinococcus multilocularis voltage dependent calcium channel 0.0125 0.0232 0.0232
Trypanosoma cruzi sterol C-24 reductase, putative 0.0046 0.0045 0.0049
Brugia malayi neuropeptide F receptor 0.0534 0.1194 0.1289
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0063 0.0084 0.0091
Mycobacterium tuberculosis Probable reductase 0.0178 0.0355 0.0789
Echinococcus granulosus calcium activated potassium channel variant 0.0063 0.0084 0.0084
Schistosoma mansoni growth hormone secretagogue receptor 0.0534 0.1194 0.1194
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0063 0.0084 0.0091
Brugia malayi photoreceptor-specific nuclear receptor 0.0138 0.0261 0.0281
Trypanosoma cruzi DNA polymerase eta, putative 0.0049 0.0053 0.0057
Schistosoma mansoni smad1 5 8 and 0.0053 0.006 0.006
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0085 0.0137 0.0137
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0048 0.0049 0.0049
Echinococcus granulosus nAChR subunit 0.0036 0.0022 0.0022
Trypanosoma brucei glucosidase, putative 0.0035 0.0019 0.002
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0027 0.0029
Onchocerca volvulus 0.0079 0.0122 0.0427
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0118 0.0214 0.1336
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0534 0.1194 0.1194
Brugia malayi nuclear receptor NHR-88 0.0138 0.0261 0.0281
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0278 0.0592 0.064
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0049 0.1322
Onchocerca volvulus 0.0063 0.0084 0.0267
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0047 0.0047
Trypanosoma brucei protein kinase, putative 0.0056 0.0069 0.0075
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Brugia malayi sulfakinin receptor protein 0.1046 0.2403 0.2594
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0061 0.0135
Giardia lamblia Pyruvate kinase 0.007 0.0101 0.0347
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0068 0.0097 0.0334
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0119 0.0217 0.0483
Schistosoma mansoni hypothetical protein 0.0072 0.0105 0.0105
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0089 0.0089
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0367 0.1261
Echinococcus granulosus neuropeptide receptor 0.0534 0.1194 0.1194
Echinococcus granulosus allatostatin A receptor 0.0534 0.1194 0.1194
Schistosoma mansoni thyroid hormone receptor 0.0138 0.0261 0.0261
Echinococcus multilocularis twik family of potassium channels 0.0063 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0039 0.0029 0.1379
Leishmania major hypothetical protein, conserved 0.0063 0.0084 0.0091
Schistosoma mansoni tar DNA-binding protein 0.007 0.0101 0.0101
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0042 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Mycobacterium leprae Probable pyruvate kinase PykA 0.007 0.0101 0.0612
Plasmodium falciparum thioredoxin reductase 0.0078 0.012 0.3269
Echinococcus multilocularis g-protein coupled receptor 0.0534 0.1194 0.1194
Schistosoma mansoni nuclear receptor 0.0065 0.0089 0.0089
Schistosoma mansoni neuropeptide receptor 0.0534 0.1194 0.1194
Echinococcus granulosus GTP binding nuclear protein Ran 0.0044 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0534 0.1194 0.1289
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Plasmodium falciparum amino acid transporter, putative 0.0048 0.0049 0.1322
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0063 0.0084 0.0091
Trypanosoma brucei CAAX amino terminal protease, putative 0.0177 0.0355 0.0383
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0068 0.0097 0.0216
Schistosoma mansoni twik family of potassium channels-related 0.0063 0.0084 0.0084
Brugia malayi Carboxylesterase family protein 0.0068 0.0097 0.0105
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0042 0.0035 0.0079
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0063 0.0084 0.0091
Schistosoma mansoni twik family of potassium channels-related 0.0063 0.0084 0.0084
Echinococcus multilocularis GPCR, family 2 0.0033 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Loa Loa (eye worm) hypothetical protein 0.0138 0.0261 0.0276
Loa Loa (eye worm) hypothetical protein 0.0065 0.0089 0.0091
Brugia malayi nuclear receptor NHR-67 0.0065 0.0089 0.0096
Loa Loa (eye worm) ACC-1 protein 0.0036 0.0022 0.0019
Loa Loa (eye worm) glutaminase 2 0.088 0.201 0.2165
Leishmania major pyruvate kinase 0.007 0.0101 0.0109
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Treponema pallidum fructose-bisphosphate aldolase 0.1261 0.2909 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0097 0.01
Schistosoma mansoni single-minded 0.0053 0.0061 0.0061
Plasmodium vivax acyl-CoA synthetase, putative 0.0039 0.0029 0.0803
Brugia malayi hypothetical protein 0.0068 0.0097 0.0105
Onchocerca volvulus 0.0055 0.0066 0.0187
Trypanosoma cruzi ion transport protein, putative 0.0063 0.0084 0.0091
Mycobacterium ulcerans pyruvate kinase 0.007 0.0101 0.0502
Echinococcus multilocularis fmrfamide receptor 0.0534 0.1194 0.1194
Leishmania major C-14 sterol reductase, putative 0.0046 0.0045 0.0049
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1261 0.2909 0.9494
Echinococcus granulosus tar DNA binding protein 0.007 0.0101 0.0101
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0063 0.0084 0.0091
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0048 0.0049 0.0047
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0102 0.0176 0.0876
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0036 0.0022 0.0019
Brugia malayi Pre-SET motif family protein 0.013 0.0243 0.0263
Brugia malayi Dopamine receptor protein 1 0.3157 0.7378 0.7965
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0036 0.0022 0.0022
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0534 0.1194 0.1194
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0069 0.0237
Schistosoma mansoni Lamin B receptor (ERG24) 0.0046 0.0045 0.0045
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0036 0.0022 0.0024
Echinococcus multilocularis neuropeptide receptor A26 0.0534 0.1194 0.1194
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0138 0.0261 0.0281
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0534 0.1194 0.1194
Echinococcus granulosus 7tm_1 domain containing protein 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Brugia malayi hypothetical protein 0.0178 0.0356 0.0384
Schistosoma mansoni sodium/chloride dependent transporter 0.0048 0.005 0.005
Loa Loa (eye worm) nuclear hormone receptor 0.0065 0.0089 0.0091
Trypanosoma cruzi C-8 sterol isomerase, putative 0.3957 0.9263 1
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0042 0.0035 0.0079
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.1327 0.3064 0.3304
Loa Loa (eye worm) hypothetical protein 0.0115 0.0207 0.0219
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.0086
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.013 0.0243 0.0243
Loa Loa (eye worm) RNA binding protein 0.007 0.0101 0.0104
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0245 0.0514 0.0514
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0042 0.0035 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0122 0.0745
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.005 0.0171
Schistosoma mansoni coup transcription factor 0.0138 0.0261 0.0261
Schistosoma mansoni hypothetical protein 0.0118 0.0215 0.0215
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0053 0.0061 0.0303
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0044 0.0039 0.1073
Loa Loa (eye worm) uncoordinated protein 58 0.0063 0.0084 0.0086
Toxoplasma gondii transporter, cation channel family protein 0.0073 0.0109 0.2965
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0125 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0084 0.0135 0.0141
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0019 0.0065
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.013 0.0242 0.1519
Schistosoma mansoni lamin 0.0117 0.0213 0.0213
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0063 0.0084 0.0091
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0534 0.1194 0.1194
Schistosoma mansoni smad1 5 8 and 0.0053 0.006 0.006
Brugia malayi Importin beta-1 subunit 0.0059 0.0076 0.0082
Loa Loa (eye worm) norepinephrine transporter 0.028 0.0597 0.0639
Schistosoma mansoni calcium-activated potassium channel 0.1225 0.2824 0.2824
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0102 0.0176 0.0176
Schistosoma mansoni pyruvate kinase 0.0036 0.0021 0.0021
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.0101 0.0338
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Schistosoma mansoni hypothetical protein 0.147 0.3401 0.3401
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0177 0.0355 0.0355
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0024 0.0054
Brugia malayi Sodium:neurotransmitter symporter family protein 0.028 0.0597 0.0644
Loa Loa (eye worm) hypothetical protein 0.013 0.0243 0.0257
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0534 0.1194 0.1194
Schistosoma mansoni voltage-gated potassium channel 0.0095 0.0161 0.0161
Echinococcus granulosus neuropeptide Y receptor 0.0534 0.1194 0.1194
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.013 0.0243 0.6627
Loa Loa (eye worm) jmjC domain-containing protein 0.0068 0.0096 0.0098
Onchocerca volvulus 0.0085 0.0137 0.0495
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0061 0.0066
Loa Loa (eye worm) hypothetical protein 0.0048 0.0049 0.0047
Brugia malayi Inositol-1 0.0038 0.0027 0.0029
Echinococcus granulosus acetylcholinesterase 0.0404 0.0888 0.0888
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0042 0.0035 0.0079
Brugia malayi MH2 domain containing protein 0.0053 0.006 0.0065
Schistosoma mansoni twik family of potassium channels-related 0.0063 0.0084 0.0084
Plasmodium falciparum pyruvate kinase 2 0.0036 0.0021 0.0568
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0042 0.0035 0.0079
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0078 0.0121 0.0602
Brugia malayi RNA binding protein 0.007 0.0101 0.0109
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0047 0.0163
Plasmodium falciparum pyruvate kinase 0.007 0.0101 0.2751
Echinococcus granulosus twik family of potassium channels 0.0063 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0079 0.0122 0.0126
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0047 0.1291
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0049 0.0052
Echinococcus granulosus TGF beta signal transducer SmadC 0.0053 0.006 0.006
Echinococcus multilocularis Smad4 0.0053 0.006 0.006
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0044 0.0039 0.0037
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0047 0.1291
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0118 0.0215 0.0215
Brugia malayi MH1 domain containing protein 0.0053 0.006 0.0065
Onchocerca volvulus Glucosylceramidase homolog 0.0183 0.0367 0.1481
Loa Loa (eye worm) melatonin receptor type 1A 0.0534 0.1194 0.1284
Schistosoma mansoni sodium/chloride dependent transporter 0.0048 0.0049 0.0049
Schistosoma mansoni ap endonuclease 0.0078 0.0121 0.0121
Plasmodium vivax glutathione reductase, putative 0.0078 0.012 0.3269
Echinococcus granulosus dna polymerase eta 0.0049 0.0053 0.0053
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0033 0.0014 0.0015
Plasmodium falciparum transporter, putative 0.0048 0.0049 0.1322
Loa Loa (eye worm) hypothetical protein 0.0534 0.1194 0.1284
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.0101 0.0338
Echinococcus multilocularis rhodopsin orphan GPCR 0.0534 0.1194 0.1194
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0102 0.0176 0.019
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0042 0.0035 0.0177
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0019 0.0065
Echinococcus granulosus p2X purinoceptor 4 0.0069 0.01 0.01
Trichomonas vaginalis pyruvate kinase, putative 0.007 0.0101 0.0347
Echinococcus multilocularis twik family of potassium channels 0.0063 0.0084 0.0084
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0119 0.0217 0.0217
Trichomonas vaginalis ap endonuclease, putative 0.0078 0.0121 0.0416
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.0061 0.0303
Trypanosoma brucei calcium-activated potassium channel, putative 0.0063 0.0084 0.0091
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0019
Schistosoma mansoni opsin-like receptor 0.0534 0.1194 0.1194
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0177 0.0355 0.1219
Plasmodium falciparum importin beta, putative 0.0059 0.0076 0.208
Schistosoma mansoni hypothetical protein 0.0063 0.0084 0.0084
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0036 0.0022 0.0024
Brugia malayi nuclear hormone receptor 0.0065 0.0089 0.0096
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0063 0.0084 0.0091

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 12 nM kg-1 Compound was evaluated for Appetite suppression, based on intake of liquid diet by food-deprived rats for 1 h following intraperitoneal injection ChEMBL. 8201591
Hydrolysis (functional) = 95 % Percent maximal stimulation of phosphatidylinositol hydrolysis in guinea pig pancreatic acini (CCK-A receptors) relative to CCK-8 ChEMBL. 8201591
Hydrolysis (functional) = 95 % Percent maximal stimulation of phosphatidylinositol hydrolysis in guinea pig pancreatic acini (CCK-A receptors) relative to CCK-8 ChEMBL. 8201591
IC50 (binding) = 35 nM In vitro inhibition of [125I]-CCK-8 binding to guinea pig pancreas ChEMBL. 8201591
IC50 (binding) = 35 nM In vitro inhibition of [125I]-CCK-8 binding to guinea pig pancreas ChEMBL. 8201591
IC50 (binding) = 4577 nM In vitro binding for inhibition of [125I]- Bolton-Hunter-CCK-8 binding in guinea pig cortex ChEMBL. 8201591
IC50 (binding) = 4577 nM In vitro binding for inhibition of [125I]- Bolton-Hunter-CCK-8 binding in guinea pig cortex ChEMBL. 8201591

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.