Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Plasmodium falciparum | heat shock protein 90, putative | Starlite/ChEMBL | No references |
Homo sapiens | arachidonate 15-lipoxygenase, type B | Starlite/ChEMBL | No references |
Homo sapiens | autophagy related 4B, cysteine peptidase | Starlite/ChEMBL | No references |
Homo sapiens | geminin, DNA replication inhibitor | Starlite/ChEMBL | No references |
Homo sapiens | cytochrome P450, family 2, subfamily C, polypeptide 9 | Starlite/ChEMBL | No references |
Homo sapiens | androgen receptor | Starlite/ChEMBL | No references |
Homo sapiens | fatty acid synthase | Starlite/ChEMBL | No references |
Mus musculus | RAR-related orphan receptor gamma | Starlite/ChEMBL | No references |
Homo sapiens | lysine (K)-specific demethylase 4A | Starlite/ChEMBL | No references |
Homo sapiens | RAR-related orphan receptor C | Starlite/ChEMBL | No references |
Homo sapiens | arachidonate 15-lipoxygenase | Starlite/ChEMBL | No references |
Homo sapiens | phospholipase A2, group IB (pancreas) | Starlite/ChEMBL | No references |
Homo sapiens | heat shock protein 90kDa alpha (cytosolic), class A member 1 | Starlite/ChEMBL | No references |
Homo sapiens | huntingtin | Starlite/ChEMBL | No references |
Influenza A virus | Nonstructural protein 1 | Starlite/ChEMBL | No references |
Homo sapiens | cytochrome P450, family 2, subfamily C, polypeptide 19 | Starlite/ChEMBL | No references |
Homo sapiens | hydroxyprostaglandin dehydrogenase 15-(NAD) | Starlite/ChEMBL | No references |
Homo sapiens | hydroxysteroid (17-beta) dehydrogenase 10 | Starlite/ChEMBL | No references |
Homo sapiens | parathyroid hormone 1 receptor | Starlite/ChEMBL | No references |
Bacillus anthracis | Anthrax lethal factor | Starlite/ChEMBL | No references |
Homo sapiens | synuclein, alpha (non A4 component of amyloid precursor) | Starlite/ChEMBL | No references |
Homo sapiens | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | Starlite/ChEMBL | No references |
Homo sapiens | cytochrome P450, family 2, subfamily D, polypeptide 6 | Starlite/ChEMBL | No references |
Homo sapiens | glucagon-like peptide 1 receptor | Starlite/ChEMBL | No references |
Homo sapiens | TAR DNA binding protein | Starlite/ChEMBL | No references |
Homo sapiens | glycoprotein hormones, alpha polypeptide | Starlite/ChEMBL | No references |
Homo sapiens | SMAD family member 2 | Starlite/ChEMBL | No references |
Homo sapiens | nuclear factor, erythroid 2-like 2 | Starlite/ChEMBL | No references |
Homo sapiens | aldehyde dehydrogenase 1 family, member A1 | Starlite/ChEMBL | No references |
Human immunodeficiency virus 1 | Aberrant vpr protein | Starlite/ChEMBL | No references |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | heat shock protein 90, putative | 0.0055 | 0.0783 | 0.6092 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.2903 | 0.2894 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0035 | 0.039 | 0.1029 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0043 | 0.0537 | 0.0683 |
Leishmania major | importin beta-1 subunit, putative | 0.0027 | 0.0223 | 0.0937 |
Brugia malayi | hypothetical protein | 0.002 | 0.0097 | 0.029 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.0783 | 0.6092 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0043 | 0.0537 | 0.0683 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0071 | 0.1093 | 1 |
Schistosoma mansoni | endoplasmin | 0.0055 | 0.0783 | 0.1064 |
Echinococcus granulosus | Peptidase C54 | 0.0071 | 0.1093 | 0.1545 |
Brugia malayi | RNA binding protein | 0.0146 | 0.2555 | 0.8795 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0175 | 0.0562 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0024 | 0.0175 | 0.0146 |
Echinococcus multilocularis | heat shock protein 90 | 0.0047 | 0.0627 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0537 | 0.0525 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0082 | 0.1309 | 0.4486 |
Schistosoma mansoni | heat shock protein | 0.0055 | 0.0783 | 0.1064 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.021 | 0.3795 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0023 | 0.0144 | 0.0131 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0043 | 0.0537 | 0.1813 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0037 | 0.0421 | 0.0502 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.003 | 0.029 | 0.0959 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0043 | 0.0537 | 0.1813 |
Schistosoma mansoni | ran | 0.0024 | 0.0175 | 0.0122 |
Echinococcus granulosus | peregrin | 0.0035 | 0.039 | 0.0455 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.0535 | 0.068 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.012 | 0.2052 | 0.7057 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.002 | 0.0084 | 0.0222 |
Echinococcus granulosus | importin subunit beta 1 | 0.0033 | 0.0345 | 0.0384 |
Schistosoma mansoni | importin beta-1 | 0.0033 | 0.0345 | 0.0384 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.039 | 0.0732 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Entamoeba histolytica | Ran family GTPase | 0.0024 | 0.0175 | 0.0494 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0043 | 0.0537 | 0.0683 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0027 | 0.0223 | 0.1047 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Echinococcus multilocularis | tar DNA binding protein | 0.0146 | 0.2555 | 0.3811 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0048 | 0.0633 | 0.0831 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0022 | 0.0125 | 0.0792 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0447 | 0.0543 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.002 | 0.0097 | 0.029 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0037 | 0.0421 | 0.0502 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0029 | 0.0272 | 0.212 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0783 | 0.6092 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0032 | 0.0327 | 0.261 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0175 | 0.0494 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0065 | 0.0964 | 0.0952 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0073 | 0.1134 | 0.1609 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0077 | 0.1207 | 0.1722 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0033 | 0.0345 | 0.2053 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0043 | 0.0537 | 0.0525 |
Schistosoma mansoni | endoplasmin | 0.0055 | 0.0783 | 0.1064 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0023 | 0.0144 | 0.0453 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0027 | 0.0223 | 0.1047 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0038 | 0.0447 | 0.1501 |
Brugia malayi | intermediate filament protein | 0.003 | 0.0281 | 0.0928 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0052 | 0.0135 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0032 | 0.0327 | 0.261 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0043 | 0.0537 | 0.0525 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0023 | 0.0144 | 0.0073 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0023 | 0.0144 | 0.0073 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0033 | 0.0345 | 0.0908 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0032 | 0.0327 | 0.086 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0043 | 0.0537 | 0.0683 |
Schistosoma mansoni | lamin | 0.003 | 0.0281 | 0.0286 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.003 | 0.029 | 0.3177 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.0783 | 0.6092 |
Echinococcus multilocularis | heat shock protein 90 | 0.0055 | 0.0783 | 0.1064 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0043 | 0.0537 | 0.0525 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0077 | 0.1207 | 1 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.003 | 0.029 | 0.2282 |
Brugia malayi | Cytochrome P450 family protein | 0.0059 | 0.0853 | 0.2906 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0021 | 0.0122 | 0.0287 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0025 | 0.0183 | 0.1318 |
Onchocerca volvulus | 0.0028 | 0.0252 | 0.0156 | |
Schistosoma mansoni | polycystin 1-related | 0.0048 | 0.0633 | 0.0831 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0783 | 0.6092 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C54, putative | 0.0028 | 0.0245 | 0.114 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0029 | 0.0272 | 0.212 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0243 | 0.1122 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0057 | 0.0815 | 0.2776 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0074 | 0.1146 | 0.3921 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.002 | 0.0097 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.039 | 0.0378 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0043 | 0.0537 | 0.0683 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0243 | 0.0332 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0043 | 0.0537 | 0.0683 |
Onchocerca volvulus | 0.003 | 0.0281 | 0.0186 | |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0281 | 0.0269 |
Brugia malayi | jmjC domain containing protein | 0.0043 | 0.0535 | 0.1806 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0551 | 0.3956 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0115 | 0.1953 | 0.2878 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0073 | 0.1134 | 0.1609 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0074 | 0.1146 | 0.1627 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.2555 | 0.3811 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0043 | 0.0537 | 0.1813 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0048 | 0.0633 | 0.1391 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0038 | 0.0447 | 0.0434 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0043 | 0.0537 | 0.0445 |
Echinococcus granulosus | heat shock protein 90 | 0.0047 | 0.0627 | 0.0822 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0045 | 0.058 | 0.4897 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.3696 | 0.558 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0074 | 0.1146 | 0.1627 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0024 | 0.0175 | 0.0122 |
Brugia malayi | ecdysone receptor | 0.002 | 0.0097 | 0.029 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0144 | 0.2516 | 0.2506 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0032 | 0.0327 | 0.261 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0038 | 0.0447 | 0.0543 |
Echinococcus granulosus | heat shock protein 90 | 0.0055 | 0.0783 | 0.1064 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.0111 | 0.1871 | 0.1792 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0024 | 0.0175 | 0.0122 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0144 | 0.2516 | 0.2506 |
Echinococcus granulosus | snurportin 1 | 0.0351 | 0.6546 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.0281 | 0.0286 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0144 | 0.0453 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0024 | 0.0175 | 0.1344 |
Echinococcus granulosus | geminin | 0.0205 | 0.3696 | 0.558 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0043 | 0.0537 | 0.1813 |
Echinococcus multilocularis | geminin | 0.0205 | 0.3696 | 0.558 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0077 | 0.1207 | 0.1196 |
Echinococcus multilocularis | heat shock protein | 0.0055 | 0.0783 | 0.1064 |
Brugia malayi | Muscleblind-like protein | 0.0164 | 0.2903 | 1 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0175 | 0.0812 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.1207 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.0281 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0144 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.2052 | 0.2042 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0551 | 0.3956 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.2555 | 0.3811 |
Schistosoma mansoni | ran | 0.0024 | 0.0175 | 0.0122 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0023 | 0.0144 | 0.0453 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.002 | 0.0097 | 0.029 |
Brugia malayi | tailless protein | 0.002 | 0.0097 | 0.029 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0097 | 0.029 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0551 | 0.3956 |
Plasmodium falciparum | cysteine protease ATG4, putative | 0.0028 | 0.0245 | 0.0337 |
Brugia malayi | nuclear receptor NHR-67 | 0.002 | 0.0097 | 0.029 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0021 | 0.0122 | 0.0763 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0028 | 0.0252 | 0.1934 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0047 | 0.0627 | 0.4656 |
Trichomonas vaginalis | heat shock protein, putative | 0.0052 | 0.0717 | 0.6127 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0537 | 0.0525 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.0122 | 0.0039 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0243 | 0.0332 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0043 | 0.0537 | 0.0683 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0243 | 0.1122 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0045 | 0.0574 | 0.074 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0043 | 0.0537 | 0.0683 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0043 | 0.0537 | 0.0683 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0043 | 0.0537 | 0.1813 |
Schistosoma mansoni | rab6-interacting | 0.0048 | 0.0633 | 0.0831 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0071 | 0.1093 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.004 | 0.0487 | 0.3762 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0071 | 0.1093 | 1 |
Trypanosoma cruzi | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0028 | 0.0245 | 0.114 |
Schistosoma mansoni | lamin | 0.003 | 0.0281 | 0.0286 |
Brugia malayi | Phospholipase A2 family protein | 0.0111 | 0.1871 | 0.643 |
Echinococcus multilocularis | peregrin | 0.0035 | 0.039 | 0.0455 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0055 | 0.0783 | 0.2064 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0048 | 0.0633 | 0.0831 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.1207 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.002 | 0.0097 | 0.0084 |
Mycobacterium ulcerans | polyketide synthase | 0.003 | 0.029 | 0.1884 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0551 | 0.3956 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0345 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Echinococcus granulosus | tar DNA binding protein | 0.0146 | 0.2555 | 0.3811 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0043 | 0.0537 | 0.0683 |
Brugia malayi | jmjC domain containing protein | 0.0115 | 0.1953 | 0.6714 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0043 | 0.0537 | 0.0683 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.003 | 0.029 | 0.1884 |
Brugia malayi | nuclear receptor RXR | 0.002 | 0.0097 | 0.029 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0038 | 0.0447 | 0.0543 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0043 | 0.0537 | 0.0683 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0447 | 0.0543 |
Trypanosoma cruzi | heat shock protein, putative | 0.0037 | 0.0421 | 0.2755 |
Plasmodium vivax | importin-beta 2, putative | 0.0033 | 0.0345 | 0.0607 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.0281 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1093 | 0.1081 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0271 | 0.0258 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0043 | 0.0537 | 0.0683 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0122 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0689 | 0.0677 |
Brugia malayi | hypothetical protein | 0.0043 | 0.0551 | 0.1862 |
Schistosoma mansoni | thyroid hormone receptor | 0.0043 | 0.0537 | 0.0683 |
Onchocerca volvulus | Huntingtin homolog | 0.0148 | 0.259 | 0.2517 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0038 | 0.0447 | 0.0543 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.0783 | 0.6092 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0035 | 0.039 | 0.1029 |
Echinococcus granulosus | cysteine protease atg4b | 0.0071 | 0.1093 | 0.1545 |
Mycobacterium ulcerans | thioesterase | 0.0025 | 0.0192 | 0.0957 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0243 | 0.0642 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0077 | 0.1207 | 1 |
Loa Loa (eye worm) | endoplasmin | 0.0055 | 0.0783 | 0.0771 |
Plasmodium falciparum | phd finger protein, putative | 0.0035 | 0.039 | 0.0732 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0055 | 0.0783 | 0.6092 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0055 | 0.0783 | 0.6092 |
Brugia malayi | hypothetical protein | 0.0048 | 0.0633 | 0.2144 |
Onchocerca volvulus | 0.003 | 0.0281 | 0.0186 | |
Plasmodium falciparum | heat shock protein 90, putative | 0.0032 | 0.0331 | 0.057 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0043 | 0.0535 | 0.068 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0537 | 0.0525 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.002 | 0.0097 | 0.029 |
Plasmodium vivax | heat shock protein 90, putative | 0.0037 | 0.0421 | 0.0814 |
Echinococcus granulosus | RUN | 0.0048 | 0.0633 | 0.0831 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0032 | 0.0327 | 0.2229 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0032 | 0.0327 | 0.3759 |
Trichomonas vaginalis | heat shock protein, putative | 0.0047 | 0.0627 | 0.5204 |
Schistosoma mansoni | heat shock protein | 0.0055 | 0.0783 | 0.1064 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0048 | 0.0633 | 0.0831 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0043 | 0.0537 | 0.0525 |
Plasmodium falciparum | importin beta, putative | 0.0033 | 0.0345 | 0.0607 |
Echinococcus multilocularis | snurportin 1 | 0.0351 | 0.6546 | 1 |
Plasmodium falciparum | heat shock protein 90, putative | 0.021 | 0.3795 | 1 |
Brugia malayi | PHD-finger family protein | 0.0035 | 0.039 | 0.1306 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0045 | 0.058 | 0.4897 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0043 | 0.0537 | 0.1813 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0074 | 0.1146 | 1 |
Leishmania major | GTP-binding protein, putative | 0.0024 | 0.0175 | 0.0494 |
Loa Loa (eye worm) | doublecortin family protein | 0.0048 | 0.0633 | 0.062 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0073 | 0.1122 | 0.111 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.1309 | 0.188 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.2555 | 0.3811 |
Toxoplasma gondii | autophagy-related cysteine peptidase atg4, putative | 0.0028 | 0.0245 | 0.0647 |
Trichomonas vaginalis | heat shock protein, putative | 0.0052 | 0.0717 | 0.6127 |
Brugia malayi | Importin beta-1 subunit | 0.0033 | 0.0345 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0043 | 0.0551 | 0.0705 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Brugia malayi | Endoplasmin precursor | 0.0055 | 0.0783 | 0.2665 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0144 | 0.0131 |
Echinococcus multilocularis | RUN | 0.0048 | 0.0633 | 0.0831 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0115 | 0.1953 | 0.2878 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0043 | 0.0537 | 0.0683 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0144 | 0.0453 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0043 | 0.0537 | 0.0683 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0175 | 0.0494 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0175 | 0.0163 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0447 | 0.0543 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0021 | 0.0121 | 0.0319 |
Schistosoma mansoni | nuclear hormone receptor | 0.0043 | 0.0537 | 0.0683 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.003 | 0.029 | 0.1884 |
Brugia malayi | nuclear hormone receptor | 0.0043 | 0.0537 | 0.1813 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.003 | 0.029 | 0.3177 |
Trichomonas vaginalis | heat shock protein, putative | 0.0055 | 0.0783 | 0.681 |
Brugia malayi | heat shock protein 90 | 0.0055 | 0.0783 | 0.2665 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0028 | 0.0252 | 0.0239 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0043 | 0.0537 | 0.0683 |
Loa Loa (eye worm) | TAR-binding protein | 0.0146 | 0.2555 | 0.2545 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.1207 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0023 | 0.0144 | 0.0073 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.0122 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0537 | 0.0525 |
Onchocerca volvulus | 0.0043 | 0.0537 | 0.0445 | |
Echinococcus granulosus | muscleblind protein | 0.0164 | 0.2903 | 0.4351 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0043 | 0.0537 | 0.1813 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0033 | 0.0345 | 0.2053 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0073 | 0.1134 | 0.9892 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0043 | 0.0537 | 0.1813 |
Schistosoma mansoni | family C54 unassigned peptidase (C54 family) | 0.0071 | 0.1093 | 0.1545 |
Mycobacterium ulcerans | polyketide synthase | 0.0032 | 0.0327 | 0.2229 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0043 | 0.0537 | 0.0525 |
Leishmania major | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0071 | 0.1093 | 0.8947 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0048 | 0.0633 | 0.0831 |
Plasmodium falciparum | endoplasmin, putative | 0.004 | 0.0487 | 0.0995 |
Entamoeba histolytica | peptidase, C54 family | 0.0028 | 0.0245 | 0.114 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0537 | 0.0525 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0052 | 0.0717 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0537 | 0.0525 |
Plasmodium vivax | endoplasmin, putative | 0.0055 | 0.0783 | 0.1801 |
Treponema pallidum | heat shock protein 90 | 0.0052 | 0.0717 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0881 | 0.0869 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0032 | 0.0019 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0043 | 0.0537 | 0.0683 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0043 | 0.0537 | 0.0445 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0055 | 0.0783 | 0.6092 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0025 | 0.0192 | 0.1613 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0073 | 0.1134 | 0.1609 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0144 | 0.0131 |
Entamoeba histolytica | peptidase, C54 family | 0.0028 | 0.0245 | 0.114 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.002 | 0.0097 | 0.029 |
Echinococcus granulosus | heat shock protein | 0.0055 | 0.0783 | 0.1064 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.2555 | 0.3811 |
Schistosoma mansoni | heat shock protein | 0.0037 | 0.0421 | 0.0502 |
Entamoeba histolytica | peptidase, C54 family | 0.0028 | 0.0245 | 0.114 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0783 | 0.6092 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0447 | 0.0434 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0447 | 0.0543 |
Echinococcus multilocularis | GPCR, family 2 | 0.0038 | 0.0447 | 0.0543 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0043 | 0.0537 | 0.0683 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C54, putative | 0.0028 | 0.0245 | 0.114 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.0281 | 0.0269 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0243 | 0.0797 |
Schistosoma mansoni | hypothetical protein | 0.0351 | 0.6546 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0048 | 0.0633 | 0.0831 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.012 | 0.2052 | 0.2042 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0045 | 0.0574 | 0.074 |
Giardia lamblia | Grp94/Hsp90 | 0.0052 | 0.0717 | 0.8997 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0037 | 0.0421 | 0.2755 |
Schistosoma mansoni | rab6-interacting | 0.0048 | 0.0633 | 0.0831 |
Trichomonas vaginalis | endoplasmin, putative | 0.004 | 0.0487 | 0.3762 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0074 | 0.1146 | 0.1627 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0073 | 0.1134 | 0.1609 |
Onchocerca volvulus | 0.0052 | 0.0724 | 0.0634 | |
Schistosoma mansoni | lipoxygenase | 0.0123 | 0.2111 | 0.3123 |
Brugia malayi | Peptidase family C54 containing protein | 0.0071 | 0.1093 | 0.3737 |
Echinococcus granulosus | lamin | 0.003 | 0.0281 | 0.0286 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.003 | 0.029 | 0.2282 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0223 | 0.0937 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0551 | 0.0705 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0164 | 0.2903 | 0.4351 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0146 | 0.2555 | 0.8795 |
Brugia malayi | Bromodomain containing protein | 0.0035 | 0.039 | 0.1306 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0037 | 0.0421 | 0.1109 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0043 | 0.0537 | 0.0445 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0146 | 0.2555 | 0.2545 |
Brugia malayi | Nuclear hormone receptor E75 | 0.002 | 0.0097 | 0.029 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.259 | 0.258 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.002 | 0.0097 | 0.0084 |
Brugia malayi | steroid hormone receptor | 0.0043 | 0.0537 | 0.1813 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0055 | 0.0783 | 0.6092 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0023 | 0.0144 | 0.0073 |
Echinococcus multilocularis | lamin | 0.003 | 0.0281 | 0.0286 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0073 | 0.1134 | 0.9886 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0049 | 0.0659 | 0.0873 |
Entamoeba histolytica | 90 kDa heat shock protein, putative | 0.0037 | 0.0421 | 0.2755 |
Echinococcus multilocularis | muscleblind protein | 0.0164 | 0.2903 | 0.4351 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0043 | 0.0551 | 0.0705 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0048 | 0.0633 | 0.0831 |
Giardia lamblia | PHD finger protein 15 | 0.0035 | 0.039 | 0.4064 |
Brugia malayi | Doublecortin family protein | 0.0048 | 0.0633 | 0.2144 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0043 | 0.0551 | 0.0705 |
Plasmodium vivax | heat shock protein, putative | 0.021 | 0.3795 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0209 | 0.3783 | 0.5715 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0073 | 0.1134 | 0.9886 |
Brugia malayi | nuclear receptor RXR | 0.0023 | 0.0144 | 0.0453 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0071 | 0.1093 | 1 |
Trichomonas vaginalis | importin beta-1, putative | 0.0027 | 0.0223 | 0.1047 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0209 | 0.3783 | 0.5715 |
Onchocerca volvulus | 0.0048 | 0.0633 | 0.0541 | |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0043 | 0.0537 | 0.1813 |
Echinococcus multilocularis | Peptidase C54 | 0.0071 | 0.1093 | 0.1545 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.0281 | 0.0269 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0073 | 0.1134 | 0.2989 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0055 | 0.0783 | 0.0771 |
Brugia malayi | hypothetical protein | 0.002 | 0.0097 | 0.029 |
Brugia malayi | MH2 domain containing protein | 0.0144 | 0.2516 | 0.8662 |
Brugia malayi | Hsp90 protein | 0.0037 | 0.0421 | 0.1411 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0077 | 0.1207 | 0.1722 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0043 | 0.0537 | 0.0683 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0043 | 0.0537 | 0.0525 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0097 | 0.029 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0045 | 0.058 | 0.4634 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0038 | 0.0447 | 0.0543 |
Schistosoma mansoni | thyroid hormone receptor | 0.0043 | 0.0537 | 0.0683 |
Mycobacterium ulcerans | thioesterase TesA | 0.0025 | 0.0192 | 0.0957 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0035 | 0.039 | 0.0378 |
Brugia malayi | Nuclear hormone receptor E75 | 0.002 | 0.0097 | 0.029 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0035 | 0.039 | 0.0455 |
Loa Loa (eye worm) | DR-78 | 0.002 | 0.0097 | 0.0084 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.039 | 0.0455 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0243 | 0.1122 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0037 | 0.0421 | 0.0327 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0043 | 0.0537 | 0.0525 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.0281 | 0.0928 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0043 | 0.0537 | 0.1813 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0144 | 0.0131 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0073 | 0.1134 | 0.9886 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0043 | 0.0537 | 0.1813 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0209 | 0.3783 | 0.5715 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.003 | 0.029 | 0.2282 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0351 | 0.6546 | 0.6542 |
Loa Loa (eye worm) | RNA binding protein | 0.0146 | 0.2555 | 0.2545 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0073 | 0.1134 | 0.9325 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0074 | 0.1146 | 1 |
Echinococcus granulosus | endoplasmin | 0.0052 | 0.0717 | 0.0961 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0243 | 0.1122 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0783 | 0.6092 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0783 | 0.6092 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0074 | 0.1146 | 0.9436 |
Schistosoma mansoni | loxhd1 | 0.0048 | 0.0633 | 0.0831 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.0528 | 1 | 1 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0024 | 0.0175 | 0.0797 |
Entamoeba histolytica | peptidase, C54 family | 0.0071 | 0.1093 | 0.8947 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Echinococcus granulosus | FTZ F1 alpha | 0.0043 | 0.0537 | 0.0683 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.0281 | 0.0286 |
Leishmania major | heat shock protein, putative | 0.0037 | 0.0421 | 0.2755 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0783 | 0.6092 |
Trypanosoma cruzi | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0071 | 0.1093 | 0.8947 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0043 | 0.0537 | 0.0683 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0144 | 0.0131 |
Brugia malayi | conserved hypotetical protein | 0.002 | 0.0097 | 0.029 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0052 | 0.0717 | 1 |
Brugia malayi | hypothetical protein | 0.0048 | 0.0633 | 0.2144 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0633 | 0.062 |
Onchocerca volvulus | Alhambra homolog | 0.0035 | 0.039 | 0.0297 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0055 | 0.0783 | 0.2064 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0054 | 0.0761 | 0.0671 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0038 | 0.0447 | 0.1501 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0537 | 0.0525 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0024 | 0.0175 | 0.0797 |
Brugia malayi | TAR-binding protein | 0.0146 | 0.2555 | 0.8795 |
Trypanosoma brucei | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0071 | 0.1093 | 0.8947 |
Plasmodium vivax | heat shock protein 86, putative | 0.0055 | 0.0783 | 0.1801 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.003 | 0.029 | 0.1884 |
Brugia malayi | RNA, U transporter 1 | 0.0093 | 0.1526 | 0.5237 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0043 | 0.0537 | 0.0683 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.259 | 0.258 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0048 | 0.0633 | 0.1391 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1309 | 0.1298 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0783 | 0.6092 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0783 | 0.6092 |
Schistosoma mansoni | family C54 unassigned peptidase (C54 family) | 0.0071 | 0.1093 | 0.1545 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0633 | 0.0831 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.003 | 0.029 | 0.1884 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.3696 | 0.558 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0043 | 0.0535 | 0.0523 |
Trichomonas vaginalis | ran, putative | 0.0024 | 0.0175 | 0.0553 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0047 | 0.0627 | 0.4656 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0043 | 0.0537 | 0.0683 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0052 | 0.0717 | 0.6129 |
Loa Loa (eye worm) | fatty acid synthase | 0.003 | 0.0282 | 0.027 |
Plasmodium falciparum | heat shock protein 90 | 0.0055 | 0.0783 | 0.1801 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0043 | 0.0537 | 0.1813 |
Onchocerca volvulus | Huntingtin homolog | 0.0148 | 0.259 | 0.2517 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0032 | 0.0327 | 0.2229 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0043 | 0.0537 | 0.0683 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0035 | 0.039 | 0.0455 |
Toxoplasma gondii | exonuclease III APE | 0.0021 | 0.0122 | 0.0321 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0047 | 0.0627 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Onchocerca volvulus | 0.0048 | 0.0633 | 0.0541 | |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0071 | 0.1093 | 1 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0077 | 0.1207 | 0.1722 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.0122 | 0.0376 |
Brugia malayi | ecdysteroid receptor | 0.0043 | 0.0537 | 0.1813 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0043 | 0.0537 | 0.0683 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.012 | 0.2052 | 0.7057 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0043 | 0.0537 | 0.1813 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0055 | 0.0783 | 0.6092 |
Brugia malayi | hypothetical protein | 0.0148 | 0.259 | 0.8917 |
Brugia malayi | nuclear receptor NHR-88 | 0.0043 | 0.0537 | 0.1813 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0043 | 0.0537 | 0.0683 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0045 | 0.058 | 0.7815 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0047 | 0.0627 | 0.7642 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0052 | 0.0717 | 0.5481 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0037 | 0.0421 | 0.0408 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0023 | 0.0156 | 0.0312 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0024 | 0.0175 | 0.0462 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0243 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0633 | 0.062 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0032 | 0.0327 | 0.3759 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0059 | 0.0853 | 0.0841 |
Leishmania major | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0028 | 0.0245 | 0.114 |
Echinococcus multilocularis | cysteine protease atg4b | 0.0071 | 0.1093 | 0.1545 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0175 | 0.0146 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0043 | 0.0537 | 0.0525 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0035 | 0.039 | 0.0455 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0043 | 0.0537 | 0.1813 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0175 | 0.0494 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.0122 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0243 | 0.0231 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0097 | 0.0084 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Echinococcus multilocularis | endoplasmin | 0.0052 | 0.0717 | 0.0961 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0033 | 0.0345 | 0.0384 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0043 | 0.0537 | 0.1813 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0077 | 0.1207 | 0.4133 |
Echinococcus granulosus | GPCR family 2 | 0.0038 | 0.0447 | 0.0543 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.0535 | 0.068 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0032 | 0.0327 | 0.3759 |
Schistosoma mansoni | coup transcription factor | 0.0043 | 0.0537 | 0.0683 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0074 | 0.1146 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.0049 | 0.0659 | 0.0873 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.2903 | 0.2894 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0043 | 0.0535 | 0.068 |
Entamoeba histolytica | peptidase, C54 family | 0.0028 | 0.0245 | 0.114 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0025 | 0.0192 | 0.14 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0055 | 0.0783 | 0.6092 |
Schistosoma mansoni | autophagin-1 (C54 family) | 0.0071 | 0.1093 | 0.1545 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0052 | 0.0717 | 0.5929 |
Trichomonas vaginalis | heat shock protein, putative | 0.0032 | 0.0331 | 0.2156 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0043 | 0.0537 | 0.0683 |
Echinococcus multilocularis | musashi | 0.003 | 0.0281 | 0.0286 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0122 | 0.0039 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0027 | 0.0223 | 0.0937 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0783 | 0.6092 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.1871 | 0.1861 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.2555 | 0.3811 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0043 | 0.0537 | 0.1813 |
Schistosoma mansoni | jumonji domain containing protein | 0.0092 | 0.1491 | 0.2162 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0055 | 0.0783 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0537 | 0.0525 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0252 | 0.0825 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
AC50 (functional) | = 3.066 uM | PUBCHEM_BIOASSAY: Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504596] | ChEMBL. | No reference |
AC50 (functional) | = 4.112 uM | PUBCHEM_BIOASSAY: HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504596] | ChEMBL. | No reference |
GI50 (functional) | -5.502 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.417 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.298 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.176 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.169 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.14 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.104 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.063 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.978 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.848 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.753 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
IC50 (functional) | 3.52 uM | PubChem BioAssay. Dose response confirmation of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a kinetic, fluorescence intensity assay. (Class of assay: confirmatory) | ChEMBL. | No reference |
IC50 (functional) | 3.55 uM | PubChem BioAssay. Dose response confirmation of uHTS inhibitor hits of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay. (Class of assay: confirmatory) | ChEMBL. | No reference |
IC50 (functional) | = 11 uM | PUBCHEM_BIOASSAY: Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504462, AID504475] | ChEMBL. | No reference |
IC50 (functional) | = 15.2 uM | PUBCHEM_BIOASSAY: Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504462, AID504475] | ChEMBL. | No reference |
IC50 (functional) | = 20.5 uM | Antimalarial activity against chloroquine-resistant Plasmodium falciparum D6 by [3H]hypoxanthine uptake | ChEMBL. | 19191586 |
IC50 (functional) | = 21.5 uM | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum W2 by [3H]hypoxanthine uptake | ChEMBL. | 19191586 |
IC50 (binding) | = 38.5 uM | Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-dUTP incorporation into DNA strand by rapid plate assay | ChEMBL. | 21438571 |
Potency (ADMET) | = 0.0794 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19. (Class of assay: confirmatory) [Related pubchem assays: 410 ] | ChEMBL. | No reference |
Potency (ADMET) | = 0.3981 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9. (Class of assay: confirmatory) [Related pubchem assays: 885, 884, 410 ] | ChEMBL. | No reference |
Potency (functional) | 0.631 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of glucocorticoid receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 1.122 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 1.2589 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 2.5119 um | PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 2.5119 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] | ChEMBL. | No reference |
Potency (functional) | = 3.1623 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (ADMET) | = 3.1623 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6. (Class of assay: confirmatory) [Related pubchem assays: 410 ] | ChEMBL. | No reference |
Potency (functional) | = 3.9811 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] | ChEMBL. | No reference |
Potency (functional) | = 3.9811 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 3.9811 uM | PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 4.7304 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 5.0119 um | PUBCHEM_BIOASSAY: qHTS Assay for Anthrax Lethal Toxin Internalization. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 5.0119 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] | ChEMBL. | No reference |
Potency (functional) | 5.6234 uM | PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 6.9031 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 7.0795 uM | PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 7.4993 uM | PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 8.9125 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] | ChEMBL. | No reference |
Potency (functional) | 9.4411 uM | PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 10 uM | PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 10 uM | PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 10.6822 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 11.2202 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] | ChEMBL. | No reference |
Potency (functional) | 12.5893 uM | PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 13.4591 uM | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] | ChEMBL. | No reference |
Potency (functional) | 14.9601 uM | PubChem BioAssay. qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 15.1014 uM | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] | ChEMBL. | No reference |
Potency (functional) | = 15.8489 um | PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] | ChEMBL. | No reference |
Potency (functional) | 15.8489 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2312, AID2537, AID2702] | ChEMBL. | No reference |
Potency (functional) | 15.8489 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] | ChEMBL. | No reference |
Potency (functional) | 17.7828 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] | ChEMBL. | No reference |
Potency (functional) | 17.7828 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of glucocorticoid receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 19.9526 um | PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 20.5962 uM | PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 22.3872 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of retinoid X receptor alpha signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 22.3872 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of farnesoid X receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 23.9145 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 24.287 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 24.4932 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 25.1189 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 25.1189 uM | PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 26.6011 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 26.6032 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 26.6795 uM | PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 26.8325 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 26.8325 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 28.1838 uM | PubChem BioAssay. qHTS assay for small molecule activators of the p53 signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 29.0929 uM | PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 29.0929 uM | PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 29.8493 uM | PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (ADMET) | = 31.6228 um | PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] | ChEMBL. | No reference |
Potency (ADMET) | = 31.6228 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] | ChEMBL. | No reference |
Potency (functional) | 31.6228 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of estrogen receptor alpha signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 31.6228 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of farnesoid X receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 31.6228 uM | PUBCHEM_BIOASSAY: qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 31.6228 um | PUBCHEM_BIOASSAY: MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Live Cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 31.6228 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-005. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 31.6228 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-008. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 31.6228 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-012. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 31.6228 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP1-003 - Assay at 40 hr. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 35.4813 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 35.4813 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of androgen receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 35.4813 uM | PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 35.4813 uM | PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 2 (EPAC2): primary screen. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for Identification of Small Molecule Inducers of Hypoxia Response. (Class of assay: confirmatory) [Related pubchem assays: 914 (Primary screen.), 915 (Primary screen.)] | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 39.8107 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of thyroid hormone receptor beta signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-009. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-020. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-002. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-017. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-021. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-010. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-018. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-007. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-014. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-019. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-024. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-006. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP1-003 - Assay at 24 hr. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 43.5558 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 43.5558 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 44.6684 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor delta signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 50.1187 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of androgen receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 50.1187 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 50.1187 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of estrogen receptor alpha signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-011. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-022. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-026. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-015. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-016. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-023. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: MultiTox-Fluor Cytotoxicity Assay - LYMP1-001 - Live Cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-025. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP1-002 - Assay at 40 hr. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-004. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-001. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-013. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-003. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 50.1187 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP1-002 - Assay at 16 hr. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 54.8335 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 56.2341 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | ChEMBL. | No reference |
Potency (functional) | 56.2341 uM | PUBCHEM_BIOASSAY: Inhibitors of USP1/UAF1: Pilot qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504878] | ChEMBL. | No reference |
Potency (functional) | 61.5242 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 63.0957 uM | PubChem BioAssay. qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 68.4501 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 74.978 uM | PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 100 uM | PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) | ChEMBL. | No reference |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | ||
Plasmodium falciparum | ChEMBL23 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.